Rank | Gene Set | Z-score |
---|---|---|
1 | lymph vessel development (GO:0001945) | 7.06083176 |
2 | endothelium development (GO:0003158) | 6.47098412 |
3 | vascular endothelial growth factor signaling pathway (GO:0038084) | 6.40905753 |
4 | positive regulation of vasculogenesis (GO:2001214) | 5.01630289 |
5 | endothelial cell morphogenesis (GO:0001886) | 4.96844241 |
6 | lymphangiogenesis (GO:0001946) | 4.80277713 |
7 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 4.71045943 |
8 | regulation of vasculogenesis (GO:2001212) | 4.68011121 |
9 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 4.64193597 |
10 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 4.53563402 |
11 | surfactant homeostasis (GO:0043129) | 4.52570057 |
12 | endodermal cell differentiation (GO:0035987) | 4.40796511 |
13 | melanin biosynthetic process (GO:0042438) | 4.31633502 |
14 | patterning of blood vessels (GO:0001569) | 4.31457845 |
15 | basement membrane organization (GO:0071711) | 4.30722728 |
16 | sprouting angiogenesis (GO:0002040) | 4.27766509 |
17 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 4.26432019 |
18 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.17053858 |
19 | cell migration involved in sprouting angiogenesis (GO:0002042) | 4.07590094 |
20 | blood vessel endothelial cell migration (GO:0043534) | 3.95481510 |
21 | endothelial cell differentiation (GO:0045446) | 3.88884867 |
22 | melanin metabolic process (GO:0006582) | 3.88869708 |
23 | blood vessel maturation (GO:0001955) | 3.61041451 |
24 | chemical homeostasis within a tissue (GO:0048875) | 3.59614404 |
25 | artery development (GO:0060840) | 3.49608786 |
26 | regulation of endothelial cell differentiation (GO:0045601) | 3.49273254 |
27 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 3.41665489 |
28 | endothelial tube morphogenesis (GO:0061154) | 3.37260235 |
29 | morphogenesis of an endothelium (GO:0003159) | 3.37260235 |
30 | secondary metabolite biosynthetic process (GO:0044550) | 3.33391220 |
31 | hemidesmosome assembly (GO:0031581) | 3.26829777 |
32 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.26148400 |
33 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.24534668 |
34 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.20325047 |
35 | Notch signaling involved in heart development (GO:0061314) | 3.17154985 |
36 | gap junction assembly (GO:0016264) | 3.13409732 |
37 | coronary vasculature morphogenesis (GO:0060977) | 3.13275148 |
38 | protein localization to endosome (GO:0036010) | 3.13175662 |
39 | hippo signaling (GO:0035329) | 3.11957975 |
40 | wound healing, spreading of cells (GO:0044319) | 3.11792237 |
41 | positive regulation of endothelial cell migration (GO:0010595) | 3.10553739 |
42 | positive regulation of protein autophosphorylation (GO:0031954) | 3.10277002 |
43 | regulation of metalloenzyme activity (GO:0048552) | 3.10129490 |
44 | keratan sulfate catabolic process (GO:0042340) | 3.05858530 |
45 | substrate-dependent cell migration (GO:0006929) | 3.02964939 |
46 | hyaluronan catabolic process (GO:0030214) | 3.00753126 |
47 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.99777907 |
48 | positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862) | 2.99627041 |
49 | ovulation from ovarian follicle (GO:0001542) | 2.98444511 |
50 | regulation of transforming growth factor beta1 production (GO:0032908) | 2.98279298 |
51 | regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) | 2.97433928 |
52 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.97012644 |
53 | cell adhesion mediated by integrin (GO:0033627) | 2.96885660 |
54 | chondrocyte proliferation (GO:0035988) | 2.93597424 |
55 | renal filtration (GO:0097205) | 2.93285201 |
56 | mRNA transcription (GO:0009299) | 2.92520922 |
57 | axon extension involved in axon guidance (GO:0048846) | 2.90244306 |
58 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.90244306 |
59 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.88830832 |
60 | cellular response to vitamin D (GO:0071305) | 2.88601593 |
61 | pericardium development (GO:0060039) | 2.87096642 |
62 | embryonic heart tube development (GO:0035050) | 2.86242779 |
63 | blood vessel remodeling (GO:0001974) | 2.84597409 |
64 | endothelial cell migration (GO:0043542) | 2.84502280 |
65 | cellular response to vitamin (GO:0071295) | 2.83201120 |
66 | glomerular filtration (GO:0003094) | 2.82851551 |
67 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.82446154 |
68 | vasculogenesis (GO:0001570) | 2.82433629 |
69 | positive regulation of focal adhesion assembly (GO:0051894) | 2.80599468 |
70 | positive regulation of cell junction assembly (GO:1901890) | 2.80599468 |
71 | glomerular visceral epithelial cell development (GO:0072015) | 2.80195316 |
72 | adhesion of symbiont to host (GO:0044406) | 2.76485470 |
73 | Rap protein signal transduction (GO:0032486) | 2.76437360 |
74 | semaphorin-plexin signaling pathway (GO:0071526) | 2.76071394 |
75 | embryonic foregut morphogenesis (GO:0048617) | 2.75994199 |
76 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 2.75476721 |
77 | blood vessel morphogenesis (GO:0048514) | 2.73935611 |
78 | positive regulation of odontogenesis (GO:0042482) | 2.73863452 |
79 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.73788645 |
80 | response to fluid shear stress (GO:0034405) | 2.72904804 |
81 | protein targeting to plasma membrane (GO:0072661) | 2.72362031 |
82 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.72294809 |
83 | negative regulation of activin receptor signaling pathway (GO:0032926) | 2.72055422 |
84 | positive regulation of adherens junction organization (GO:1903393) | 2.71126495 |
85 | establishment of endothelial barrier (GO:0061028) | 2.70075384 |
86 | exocrine pancreas development (GO:0031017) | 2.69907515 |
87 | cell migration involved in heart development (GO:0060973) | 2.68727809 |
88 | negative regulation of BMP signaling pathway (GO:0030514) | 2.68342287 |
89 | collagen fibril organization (GO:0030199) | 2.67722781 |
90 | transcytosis (GO:0045056) | 2.67255144 |
91 | regulation of pathway-restricted SMAD protein phosphorylation (GO:0060393) | 2.66620473 |
92 | regulation of cardioblast differentiation (GO:0051890) | 2.66005563 |
93 | negative regulation of vascular permeability (GO:0043116) | 2.65662965 |
94 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.65395416 |
95 | regulation of endothelial cell migration (GO:0010594) | 2.65375042 |
96 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.64829467 |
97 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.64602909 |
98 | anterior/posterior axis specification, embryo (GO:0008595) | 2.62493447 |
99 | extracellular negative regulation of signal transduction (GO:1900116) | 2.61788475 |
100 | extracellular regulation of signal transduction (GO:1900115) | 2.61788475 |
101 | decidualization (GO:0046697) | 2.61330547 |
102 | negative regulation of Rho protein signal transduction (GO:0035024) | 2.61041138 |
103 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.60576532 |
104 | positive regulation of epithelial cell migration (GO:0010634) | 2.60321803 |
105 | endothelial cell proliferation (GO:0001935) | 2.60055360 |
106 | heart trabecula formation (GO:0060347) | 2.59652244 |
107 | smooth muscle tissue development (GO:0048745) | 2.59613404 |
108 | radial glial cell differentiation (GO:0060019) | 2.58913868 |
109 | venous blood vessel morphogenesis (GO:0048845) | 2.58808554 |
110 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.58571158 |
111 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 2.57991623 |
112 | collagen metabolic process (GO:0032963) | 2.57535935 |
113 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 2.55414872 |
114 | response to hepatocyte growth factor (GO:0035728) | 2.55414872 |
115 | lung vasculature development (GO:0060426) | 2.54918881 |
116 | extracellular matrix disassembly (GO:0022617) | 2.53598010 |
117 | activin receptor signaling pathway (GO:0032924) | 2.53075916 |
118 | neural crest cell development (GO:0014032) | 2.52956672 |
119 | protein localization to cell surface (GO:0034394) | 2.51197604 |
120 | collagen catabolic process (GO:0030574) | 2.51050310 |
121 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.50041888 |
122 | wound healing, spreading of epidermal cells (GO:0035313) | 2.49277057 |
123 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.48898230 |
124 | positive regulation of endothelial cell proliferation (GO:0001938) | 2.48534463 |
125 | mesenchymal cell development (GO:0014031) | 2.48330451 |
126 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.48278579 |
127 | regulation of establishment of cell polarity (GO:2000114) | 2.47608348 |
128 | cell-substrate junction assembly (GO:0007044) | 2.47014263 |
129 | apoptotic cell clearance (GO:0043277) | 2.46738626 |
130 | membrane raft organization (GO:0031579) | 2.46537829 |
131 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.45871476 |
132 | regulation of protein autophosphorylation (GO:0031952) | 2.45782881 |
133 | angiogenesis involved in wound healing (GO:0060055) | 2.45167119 |
134 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.44950176 |
135 | adherens junction assembly (GO:0034333) | 2.44775702 |
136 | regulation of epithelial cell migration (GO:0010632) | 2.44688568 |
137 | virion attachment to host cell (GO:0019062) | 2.43671863 |
138 | adhesion of symbiont to host cell (GO:0044650) | 2.43671863 |
139 | nodal signaling pathway (GO:0038092) | 2.43441827 |
140 | artery morphogenesis (GO:0048844) | 2.43108140 |
141 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.42522734 |
142 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.42105529 |
143 | positive regulation of osteoblast proliferation (GO:0033690) | 2.42098634 |
144 | phospholipid scrambling (GO:0017121) | 2.41519900 |
145 | plasma membrane repair (GO:0001778) | 2.41386556 |
146 | L-serine transport (GO:0015825) | 2.41357875 |
147 | skin morphogenesis (GO:0043589) | 2.40757634 |
148 | vitamin transmembrane transport (GO:0035461) | 2.40749564 |
149 | regulation of endothelial cell apoptotic process (GO:2000351) | 2.40358764 |
150 | germ cell migration (GO:0008354) | 2.40252664 |
151 | glomerular epithelial cell development (GO:0072310) | 2.40010146 |
152 | regulation of chemokine biosynthetic process (GO:0045073) | 2.39126157 |
153 | phagocytosis, recognition (GO:0006910) | 2.38891617 |
154 | negative regulation of catenin import into nucleus (GO:0035414) | 2.38868208 |
155 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.37756974 |
156 | positive regulation of p38MAPK cascade (GO:1900745) | 2.37239198 |
157 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.36970732 |
158 | regulation of axon guidance (GO:1902667) | 2.36584485 |
159 | mesodermal cell differentiation (GO:0048333) | 2.36282582 |
160 | regulation of mesoderm development (GO:2000380) | 2.36232886 |
161 | lung lobe morphogenesis (GO:0060463) | 2.36023086 |
162 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.35847627 |
163 | positive regulation of hormone biosynthetic process (GO:0046886) | 2.35524679 |
164 | heart trabecula morphogenesis (GO:0061384) | 2.35497101 |
165 | negative regulation of cell fate specification (GO:0009996) | 2.34985251 |
166 | trabecula morphogenesis (GO:0061383) | 2.34884550 |
167 | layer formation in cerebral cortex (GO:0021819) | 2.34362525 |
168 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 2.32386266 |
169 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.32047899 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.41321500 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.94758102 |
3 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.07832352 |
4 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.92050485 |
5 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.85324253 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.76661199 |
7 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.38181157 |
8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.36298059 |
9 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.28733685 |
10 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.24307329 |
11 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.23999460 |
12 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.16211152 |
13 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.04137249 |
14 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.97930167 |
15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.94831734 |
16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.94508729 |
17 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.93166315 |
18 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.87614702 |
19 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.86501829 |
20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.84892244 |
21 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.76458327 |
22 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.76458327 |
23 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.76458327 |
24 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.75526019 |
25 | CJUN_26792858_Chip-Seq_BT549_Human | 1.73098013 |
26 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.70239237 |
27 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.67243395 |
28 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.66650257 |
29 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.66254910 |
30 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.65924715 |
31 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.62599307 |
32 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.58430102 |
33 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.58309243 |
34 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56250396 |
35 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.54694339 |
36 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.54082597 |
37 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.53977307 |
38 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.52187916 |
39 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.51788517 |
40 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.50218620 |
41 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.49203063 |
42 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.48626636 |
43 | TP53_16413492_ChIP-PET_HCT116_Human | 1.48150410 |
44 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.44001872 |
45 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.43731711 |
46 | RXR_22108803_ChIP-Seq_LS180_Human | 1.43045508 |
47 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.39954808 |
48 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.39814413 |
49 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.39269884 |
50 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.38808152 |
51 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.38548246 |
52 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.38548246 |
53 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.37237089 |
54 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.36870490 |
55 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.36337539 |
56 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.35749381 |
57 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.35749381 |
58 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.35693005 |
59 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.35273941 |
60 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.32285649 |
61 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.32090621 |
62 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.31123694 |
63 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.31034002 |
64 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.31034002 |
65 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.30650956 |
66 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.29755318 |
67 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.29668417 |
68 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.28242553 |
69 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.26887684 |
70 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.26630436 |
71 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26393745 |
72 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.25120226 |
73 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.25101446 |
74 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24038767 |
75 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.23856651 |
76 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.21553943 |
77 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.20568852 |
78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.18125732 |
79 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.17580996 |
80 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.16187631 |
81 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.16187631 |
82 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.15976344 |
83 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.15565072 |
84 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15020656 |
85 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.14433501 |
86 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.14425712 |
87 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.13827942 |
88 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.13717221 |
89 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.13160316 |
90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12313693 |
91 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.11706930 |
92 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.11227255 |
93 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.07840699 |
94 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.06992972 |
95 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.06640945 |
96 | KDM2B_26808549_Chip-Seq_K562_Human | 1.05475442 |
97 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.05358281 |
98 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.05197074 |
99 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.04936197 |
100 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03929955 |
101 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.03817178 |
102 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.03324987 |
103 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.02782803 |
104 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.01890156 |
105 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.00797669 |
106 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.00649631 |
107 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.00493658 |
108 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.99918159 |
109 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99635019 |
110 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.99617658 |
111 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98654714 |
112 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.98557492 |
113 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98313740 |
114 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98237289 |
115 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.98156909 |
116 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.97908950 |
117 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97879700 |
118 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.97854522 |
119 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.97818039 |
120 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.97522087 |
121 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.97342083 |
122 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.97258909 |
123 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.96726942 |
124 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.96312909 |
125 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.95999027 |
126 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95996932 |
127 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.95976183 |
128 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95915285 |
129 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.95619299 |
130 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.95493470 |
131 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.94973657 |
132 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.94795495 |
133 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.94721628 |
134 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.94516955 |
135 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.94355275 |
136 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.94225880 |
137 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.93382319 |
138 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.93147057 |
139 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.92525587 |
140 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.90446748 |
141 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.90313041 |
142 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.89658683 |
143 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.88582677 |
144 | VDR_22108803_ChIP-Seq_LS180_Human | 0.88211522 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010368_abnormal_lymphatic_system | 5.67031242 |
2 | MP0001879_abnormal_lymphatic_vessel | 4.73337512 |
3 | MP0004272_abnormal_basement_membrane | 4.72377750 |
4 | MP0005167_abnormal_blood-brain_barrier | 3.89927052 |
5 | MP0005171_absent_coat_pigmentation | 3.59908506 |
6 | MP0003705_abnormal_hypodermis_morpholog | 3.09679829 |
7 | MP0000372_irregular_coat_pigmentation | 3.03733865 |
8 | MP0005623_abnormal_meninges_morphology | 2.92689115 |
9 | MP0003279_aneurysm | 2.47594200 |
10 | MP0003566_abnormal_cell_adhesion | 2.31756712 |
11 | MP0006054_spinal_hemorrhage | 2.31193444 |
12 | MP0008438_abnormal_cutaneous_collagen | 2.28231256 |
13 | MP0002254_reproductive_system_inflammat | 2.17090866 |
14 | MP0003828_pulmonary_edema | 2.04717301 |
15 | MP0006138_congestive_heart_failure | 2.02010375 |
16 | MP0004084_abnormal_cardiac_muscle | 1.99650688 |
17 | MP0003300_gastrointestinal_ulcer | 1.79337901 |
18 | MP0001958_emphysema | 1.78711599 |
19 | MP0003091_abnormal_cell_migration | 1.78289249 |
20 | MP0003890_abnormal_embryonic-extraembry | 1.77559340 |
21 | MP0005408_hypopigmentation | 1.77330086 |
22 | MP0009384_cardiac_valve_regurgitation | 1.71161555 |
23 | MP0000767_abnormal_smooth_muscle | 1.70732792 |
24 | MP0001542_abnormal_bone_strength | 1.68597412 |
25 | MP0004484_altered_response_of | 1.68111952 |
26 | MP0000733_abnormal_muscle_development | 1.66291541 |
27 | MP0005275_abnormal_skin_tensile | 1.63821859 |
28 | MP0010234_abnormal_vibrissa_follicle | 1.62288184 |
29 | MP0002877_abnormal_melanocyte_morpholog | 1.52961526 |
30 | MP0002009_preneoplasia | 1.49216930 |
31 | MP0003195_calcinosis | 1.47725274 |
32 | MP0002925_abnormal_cardiovascular_devel | 1.47464038 |
33 | MP0002295_abnormal_pulmonary_circulatio | 1.43198185 |
34 | MP0005165_increased_susceptibility_to | 1.40234038 |
35 | MP0005367_renal/urinary_system_phenotyp | 1.37096536 |
36 | MP0000516_abnormal_urinary_system | 1.37096536 |
37 | MP0005084_abnormal_gallbladder_morpholo | 1.36917422 |
38 | MP0000013_abnormal_adipose_tissue | 1.34690671 |
39 | MP0002128_abnormal_blood_circulation | 1.31772465 |
40 | MP0010352_gastrointestinal_tract_polyps | 1.31334324 |
41 | MP0008004_abnormal_stomach_pH | 1.29197883 |
42 | MP0005257_abnormal_intraocular_pressure | 1.27622549 |
43 | MP0005248_abnormal_Harderian_gland | 1.25093767 |
44 | MP0001915_intracranial_hemorrhage | 1.25032196 |
45 | MP0000465_gastrointestinal_hemorrhage | 1.24790666 |
46 | MP0005595_abnormal_vascular_smooth | 1.22111715 |
47 | MP0003191_abnormal_cellular_cholesterol | 1.22008203 |
48 | MP0003878_abnormal_ear_physiology | 1.17681301 |
49 | MP0005377_hearing/vestibular/ear_phenot | 1.17681301 |
50 | MP0002998_abnormal_bone_remodeling | 1.16271030 |
51 | MP0010678_abnormal_skin_adnexa | 1.14982742 |
52 | MP0003724_increased_susceptibility_to | 1.14630586 |
53 | MP0001614_abnormal_blood_vessel | 1.14555658 |
54 | MP0003943_abnormal_hepatobiliary_system | 1.14526973 |
55 | MP0001346_abnormal_lacrimal_gland | 1.13796886 |
56 | MP0008775_abnormal_heart_ventricle | 1.13719743 |
57 | MP0005023_abnormal_wound_healing | 1.13322820 |
58 | MP0003941_abnormal_skin_development | 1.13307111 |
59 | MP0002127_abnormal_cardiovascular_syste | 1.11979915 |
60 | MP0005503_abnormal_tendon_morphology | 1.11946423 |
61 | MP0010630_abnormal_cardiac_muscle | 1.11406314 |
62 | MP0002933_joint_inflammation | 1.10011578 |
63 | MP0003045_fibrosis | 1.08495172 |
64 | MP0000569_abnormal_digit_pigmentation | 1.07497462 |
65 | MP0003448_altered_tumor_morphology | 1.06964439 |
66 | MP0000249_abnormal_blood_vessel | 1.05810246 |
67 | MP0002108_abnormal_muscle_morphology | 1.04959184 |
68 | MP0004883_abnormal_blood_vessel | 1.04443711 |
69 | MP0005409_darkened_coat_color | 1.03991749 |
70 | MP0009278_abnormal_bone_marrow | 1.03230949 |
71 | MP0002138_abnormal_hepatobiliary_system | 1.02918956 |
72 | MP0002168_other_aberrant_phenotype | 1.01888339 |
73 | MP0005385_cardiovascular_system_phenoty | 1.00409709 |
74 | MP0001544_abnormal_cardiovascular_syste | 1.00409709 |
75 | MP0003453_abnormal_keratinocyte_physiol | 0.97879974 |
76 | MP0002972_abnormal_cardiac_muscle | 0.97861258 |
77 | MP0000383_abnormal_hair_follicle | 0.97384640 |
78 | MP0003935_abnormal_craniofacial_develop | 0.97091105 |
79 | MP0005164_abnormal_response_to | 0.95043091 |
80 | MP0002896_abnormal_bone_mineralization | 0.94743145 |
81 | MP0002098_abnormal_vibrissa_morphology | 0.94134628 |
82 | MP0001849_ear_inflammation | 0.94118149 |
83 | MP0003303_peritoneal_inflammation | 0.92874323 |
84 | MP0000537_abnormal_urethra_morphology | 0.92574006 |
85 | MP0000371_diluted_coat_color | 0.91962222 |
86 | MP0001533_abnormal_skeleton_physiology | 0.90994861 |
87 | MP0001784_abnormal_fluid_regulation | 0.89187194 |
88 | MP0000751_myopathy | 0.88720047 |
89 | MP0003385_abnormal_body_wall | 0.88446964 |
90 | MP0010030_abnormal_orbit_morphology | 0.87334219 |
91 | MP0004215_abnormal_myocardial_fiber | 0.87131847 |
92 | MP0000266_abnormal_heart_morphology | 0.87018528 |
93 | MP0005330_cardiomyopathy | 0.86575576 |
94 | MP0003950_abnormal_plasma_membrane | 0.86273659 |
95 | MP0002166_altered_tumor_susceptibility | 0.86133041 |
96 | MP0002086_abnormal_extraembryonic_tissu | 0.85480770 |
97 | MP0000749_muscle_degeneration | 0.84991999 |
98 | MP0005508_abnormal_skeleton_morphology | 0.83014213 |
99 | MP0000343_altered_response_to | 0.82123785 |
100 | MP0005388_respiratory_system_phenotype | 0.82007654 |
101 | MP0002133_abnormal_respiratory_system | 0.82007654 |
102 | MP0000377_abnormal_hair_follicle | 0.81672836 |
103 | MP0010386_abnormal_urinary_bladder | 0.80680902 |
104 | MP0004808_abnormal_hematopoietic_stem | 0.79200630 |
105 | MP0005395_other_phenotype | 0.78258487 |
106 | MP0002332_abnormal_exercise_endurance | 0.78075664 |
107 | MP0005390_skeleton_phenotype | 0.76652758 |
108 | MP0005620_abnormal_muscle_contractility | 0.76591824 |
109 | MP0009840_abnormal_foam_cell | 0.76238304 |
110 | MP0009780_abnormal_chondrocyte_physiolo | 0.76197908 |
111 | MP0005197_abnormal_uvea_morphology | 0.74689663 |
112 | MP0000003_abnormal_adipose_tissue | 0.74473371 |
113 | MP0000762_abnormal_tongue_morphology | 0.73643568 |
114 | MP0009697_abnormal_copulation | 0.73021882 |
115 | MP0001243_abnormal_dermal_layer | 0.72843792 |
116 | MP0003795_abnormal_bone_structure | 0.72474669 |
117 | MP0010307_abnormal_tumor_latency | 0.71983917 |
118 | MP0006082_CNS_inflammation | 0.70079817 |
119 | MP0005083_abnormal_biliary_tract | 0.69684697 |
120 | MP0004085_abnormal_heartbeat | 0.68605050 |
121 | MP0003122_maternal_imprinting | 0.68544699 |
122 | MP0001191_abnormal_skin_condition | 0.67818602 |
123 | MP0004510_myositis | 0.67266960 |
124 | MP0002115_abnormal_skeleton_extremities | 0.66859041 |
125 | MP0001216_abnormal_epidermal_layer | 0.66654831 |
126 | MP0004036_abnormal_muscle_relaxation | 0.66344381 |
127 | MP0009250_abnormal_appendicular_skeleto | 0.65823141 |
128 | MP0001661_extended_life_span | 0.64777445 |
129 | MP0002060_abnormal_skin_morphology | 0.64168360 |
130 | MP0005187_abnormal_penis_morphology | 0.64060766 |
131 | MP0002090_abnormal_vision | 0.63480845 |
132 | MP0008007_abnormal_cellular_replicative | 0.61343510 |
133 | MP0000579_abnormal_nail_morphology | 0.61302884 |
134 | MP0002148_abnormal_hypersensitivity_rea | 0.59951796 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cerebral aneurysm (HP:0004944) | 4.17056688 |
2 | Aortic aneurysm (HP:0004942) | 3.92084153 |
3 | Premature rupture of membranes (HP:0001788) | 3.77509280 |
4 | Protrusio acetabuli (HP:0003179) | 3.73059677 |
5 | Hematochezia (HP:0002573) | 3.54889319 |
6 | Subacute progressive viral hepatitis (HP:0006572) | 3.47780963 |
7 | Polycythemia (HP:0001901) | 3.44402987 |
8 | Vascular tortuosity (HP:0004948) | 3.14692285 |
9 | Myocardial infarction (HP:0001658) | 3.13869505 |
10 | Arterial tortuosity (HP:0005116) | 3.13498873 |
11 | Aortic dissection (HP:0002647) | 3.13420690 |
12 | Shallow orbits (HP:0000586) | 3.12034331 |
13 | Atrophic scars (HP:0001075) | 2.97819227 |
14 | Hypoplasia of the iris (HP:0007676) | 2.93951705 |
15 | Broad metatarsal (HP:0001783) | 2.78766262 |
16 | Cardiovascular calcification (HP:0011915) | 2.72260601 |
17 | Enlarged penis (HP:0000040) | 2.67770309 |
18 | Asymmetric septal hypertrophy (HP:0001670) | 2.61055356 |
19 | Onycholysis (HP:0001806) | 2.60058684 |
20 | Mutism (HP:0002300) | 2.57729726 |
21 | Short 4th metacarpal (HP:0010044) | 2.57157499 |
22 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.57157499 |
23 | Aneurysm (HP:0002617) | 2.54600258 |
24 | Spinal rigidity (HP:0003306) | 2.48144400 |
25 | Blue sclerae (HP:0000592) | 2.47755879 |
26 | Abnormality of glycolipid metabolism (HP:0010969) | 2.46561275 |
27 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.46561275 |
28 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.46561275 |
29 | Stenosis of the external auditory canal (HP:0000402) | 2.45027628 |
30 | * Esophageal varix (HP:0002040) | 2.42992986 |
31 | Dilatation of the ascending aorta (HP:0005111) | 2.41368487 |
32 | Milia (HP:0001056) | 2.41349175 |
33 | Aplasia cutis congenita (HP:0001057) | 2.39298364 |
34 | Type 1 muscle fiber predominance (HP:0003803) | 2.37798236 |
35 | Overgrowth (HP:0001548) | 2.37304919 |
36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.36991806 |
37 | Facial diplegia (HP:0001349) | 2.36155628 |
38 | Lymphangioma (HP:0100764) | 2.27932286 |
39 | Abnormality of the right ventricle (HP:0001707) | 2.25273593 |
40 | Short hallux (HP:0010109) | 2.22793596 |
41 | Mitral valve prolapse (HP:0001634) | 2.22690093 |
42 | Natal tooth (HP:0000695) | 2.21348601 |
43 | Vascular calcification (HP:0004934) | 2.19545096 |
44 | Scapular winging (HP:0003691) | 2.17034368 |
45 | Follicular hyperkeratosis (HP:0007502) | 2.16293736 |
46 | Capillary hemangiomas (HP:0005306) | 2.13733043 |
47 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.13284608 |
48 | Aplasia of the phalanges of the hand (HP:0009802) | 2.13284608 |
49 | Aplasia involving bones of the extremities (HP:0009825) | 2.13284608 |
50 | * Adactyly (HP:0009776) | 2.11747828 |
51 | Hypophosphatemic rickets (HP:0004912) | 2.09402658 |
52 | Increased connective tissue (HP:0009025) | 2.08654582 |
53 | Plantar hyperkeratosis (HP:0007556) | 2.07421402 |
54 | Blue irides (HP:0000635) | 2.05904906 |
55 | Metaphyseal dysplasia (HP:0100255) | 2.04943551 |
56 | Hypopigmentation of the fundus (HP:0007894) | 2.04924284 |
57 | Popliteal pterygium (HP:0009756) | 2.04013866 |
58 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.02366095 |
59 | Increased density of long bones (HP:0006392) | 2.01800334 |
60 | Conjunctival telangiectasia (HP:0000524) | 2.01460109 |
61 | Asymmetry of the thorax (HP:0001555) | 2.01402909 |
62 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.00855738 |
63 | Fragile nails (HP:0001808) | 2.00345691 |
64 | Absent frontal sinuses (HP:0002688) | 1.99844056 |
65 | Right ventricular cardiomyopathy (HP:0011663) | 1.98369599 |
66 | Venous abnormality (HP:0002624) | 1.97103493 |
67 | Vertebral compression fractures (HP:0002953) | 1.96391629 |
68 | Abnormality of the acetabulum (HP:0003170) | 1.96125005 |
69 | Abnormality of the calf musculature (HP:0001430) | 1.94119048 |
70 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.94112672 |
71 | Venous insufficiency (HP:0005293) | 1.92332285 |
72 | Advanced eruption of teeth (HP:0006288) | 1.91413838 |
73 | Tetraparesis (HP:0002273) | 1.90752845 |
74 | Bronchomalacia (HP:0002780) | 1.90670821 |
75 | Knee flexion contracture (HP:0006380) | 1.90337335 |
76 | Increased variability in muscle fiber diameter (HP:0003557) | 1.88541081 |
77 | Visceral angiomatosis (HP:0100761) | 1.88451662 |
78 | Bladder carcinoma (HP:0002862) | 1.87810428 |
79 | Bladder neoplasm (HP:0009725) | 1.87810428 |
80 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.87738008 |
81 | Nemaline bodies (HP:0003798) | 1.87524720 |
82 | Hyporeflexia of lower limbs (HP:0002600) | 1.87475562 |
83 | Abnormality of Sharpey fibers (HP:0100685) | 1.86681164 |
84 | Thick nail (HP:0001805) | 1.85810916 |
85 | Wormian bones (HP:0002645) | 1.84070569 |
86 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.83211032 |
87 | Single umbilical artery (HP:0001195) | 1.83211032 |
88 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.83211032 |
89 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.83079603 |
90 | Camptodactyly of toe (HP:0001836) | 1.82840770 |
91 | Spontaneous hematomas (HP:0007420) | 1.82453439 |
92 | Hemiplegia (HP:0002301) | 1.82241790 |
93 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.81964944 |
94 | Elbow flexion contracture (HP:0002987) | 1.81728812 |
95 | Wrist flexion contracture (HP:0001239) | 1.81615482 |
96 | Hemangiomatosis (HP:0007461) | 1.80713833 |
97 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.80447320 |
98 | Leiomyosarcoma (HP:0100243) | 1.80247945 |
99 | Uterine leiomyosarcoma (HP:0002891) | 1.80247945 |
100 | Abnormality of the nasal septum (HP:0000419) | 1.80091242 |
101 | Ovoid vertebral bodies (HP:0003300) | 1.79501254 |
102 | Buphthalmos (HP:0000557) | 1.79383747 |
103 | Micronodular cirrhosis (HP:0001413) | 1.76709764 |
104 | Ankyloglossia (HP:0010296) | 1.76147449 |
105 | Abnormality of the 4th metacarpal (HP:0010012) | 1.76015236 |
106 | Cervical subluxation (HP:0003308) | 1.75945665 |
107 | Lipoatrophy (HP:0100578) | 1.75583788 |
108 | Distal lower limb muscle weakness (HP:0009053) | 1.75344939 |
109 | Bladder diverticulum (HP:0000015) | 1.75033670 |
110 | Atrioventricular block (HP:0001678) | 1.74944295 |
111 | Nuclear cataract (HP:0100018) | 1.74092538 |
112 | Spinal cord lesions (HP:0100561) | 1.73965919 |
113 | Syringomyelia (HP:0003396) | 1.73965919 |
114 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.73413480 |
115 | Dysostosis multiplex (HP:0000943) | 1.72901861 |
116 | Hypoalphalipoproteinemia (HP:0003233) | 1.72723484 |
117 | Sudden death (HP:0001699) | 1.72678715 |
118 | Genu recurvatum (HP:0002816) | 1.72446805 |
119 | Mucopolysacchariduria (HP:0008155) | 1.72311535 |
120 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.72311535 |
121 | Pulmonic stenosis (HP:0001642) | 1.71900484 |
122 | Hydroureter (HP:0000072) | 1.71288366 |
123 | Rectal prolapse (HP:0002035) | 1.71279849 |
124 | Ankle contracture (HP:0006466) | 1.71133966 |
125 | Striae distensae (HP:0001065) | 1.70965940 |
126 | Metaphyseal irregularity (HP:0003025) | 1.70955791 |
127 | Aortic valve stenosis (HP:0001650) | 1.70609216 |
128 | Alopecia of scalp (HP:0002293) | 1.70221884 |
129 | Spondylolisthesis (HP:0003302) | 1.70127979 |
130 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.69461903 |
131 | Femoral bowing (HP:0002980) | 1.69423319 |
132 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.69298050 |
133 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.69298050 |
134 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.69298050 |
135 | Cerebral hemorrhage (HP:0001342) | 1.68858562 |
136 | Muscle fiber splitting (HP:0003555) | 1.68353729 |
137 | Joint stiffness (HP:0001387) | 1.68285030 |
138 | Abnormality of proline metabolism (HP:0010907) | 1.68237477 |
139 | Hydroxyprolinuria (HP:0003080) | 1.68237477 |
140 | Short middle phalanx of the 5th finger (HP:0004220) | 1.67537473 |
141 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.67280425 |
142 | Confusion (HP:0001289) | 1.66583247 |
143 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.66205462 |
144 | Osteolytic defects of the hand bones (HP:0009699) | 1.66205462 |
145 | Fragile skin (HP:0001030) | 1.65803856 |
146 | Acanthosis nigricans (HP:0000956) | 1.65272655 |
147 | Focal segmental glomerulosclerosis (HP:0000097) | 1.64987564 |
148 | Difficulty running (HP:0009046) | 1.64959934 |
149 | Bicuspid aortic valve (HP:0001647) | 1.64037668 |
150 | Abnormality of the peritoneum (HP:0002585) | 1.63516608 |
151 | * Portal hypertension (HP:0001409) | 1.62931816 |
152 | * Skull defect (HP:0001362) | 1.60989230 |
153 | Hyperextensible skin (HP:0000974) | 1.60398500 |
154 | Broad ribs (HP:0000885) | 1.59560501 |
155 | Limited hip movement (HP:0008800) | 1.59039678 |
156 | Hypoplastic ischia (HP:0003175) | 1.57130565 |
157 | Nonimmune hydrops fetalis (HP:0001790) | 1.56710069 |
158 | Soft skin (HP:0000977) | 1.56084909 |
159 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.56027430 |
160 | * Absent toe (HP:0010760) | 1.55095571 |
161 | Narrow palate (HP:0000189) | 1.54680011 |
162 | Growth hormone excess (HP:0000845) | 1.54573372 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 6.40558288 |
2 | KDR | 6.27793607 |
3 | TGFBR2 | 2.96589771 |
4 | ACVR1B | 2.77150560 |
5 | ERBB4 | 2.73543811 |
6 | MST1R | 2.63804790 |
7 | MYLK | 2.62625551 |
8 | LATS1 | 2.53633597 |
9 | TRIB3 | 2.35256769 |
10 | INSRR | 2.28763964 |
11 | RIPK1 | 2.18844536 |
12 | EIF2AK3 | 2.16088334 |
13 | FLT3 | 2.01226245 |
14 | PTK2B | 2.00384595 |
15 | DMPK | 1.96884124 |
16 | NUAK1 | 1.93685851 |
17 | PDK2 | 1.76819592 |
18 | MST4 | 1.70352082 |
19 | PDGFRA | 1.67779183 |
20 | BRSK2 | 1.67675059 |
21 | IRAK3 | 1.67591367 |
22 | FER | 1.67234012 |
23 | EPHB2 | 1.64823132 |
24 | BMX | 1.60343324 |
25 | TTN | 1.57033117 |
26 | MARK3 | 1.55568316 |
27 | FGFR2 | 1.50497073 |
28 | TGFBR1 | 1.48487470 |
29 | DDR2 | 1.46002730 |
30 | MELK | 1.40262975 |
31 | LRRK2 | 1.38020846 |
32 | MET | 1.35496528 |
33 | MOS | 1.33485553 |
34 | GRK7 | 1.33200600 |
35 | PRKG2 | 1.33137690 |
36 | PTK6 | 1.27445694 |
37 | MAP3K14 | 1.25760422 |
38 | TSSK6 | 1.24916246 |
39 | PTK2 | 1.20890366 |
40 | PBK | 1.20641736 |
41 | CAMK1D | 1.20158180 |
42 | FGFR3 | 1.18724534 |
43 | BMPR1B | 1.15992370 |
44 | AKT3 | 1.15220135 |
45 | STK10 | 1.14966785 |
46 | TRIM28 | 1.14399307 |
47 | CAMK1G | 1.11451598 |
48 | MKNK2 | 1.10435865 |
49 | PKN2 | 1.07722893 |
50 | MAPK12 | 0.99526945 |
51 | CDK6 | 0.97492341 |
52 | PAK4 | 0.96645581 |
53 | FRK | 0.96598162 |
54 | EPHA4 | 0.95265887 |
55 | NTRK1 | 0.94665278 |
56 | ITK | 0.91897952 |
57 | FGFR1 | 0.90052519 |
58 | STK3 | 0.89336412 |
59 | PRKD3 | 0.88715262 |
60 | IGF1R | 0.82919399 |
61 | MUSK | 0.82728042 |
62 | PIK3CG | 0.82683820 |
63 | TAF1 | 0.81369281 |
64 | MAPK7 | 0.80331061 |
65 | NLK | 0.80217394 |
66 | STK38L | 0.79668660 |
67 | PDGFRB | 0.77020392 |
68 | PRKAA2 | 0.77016217 |
69 | LATS2 | 0.75457142 |
70 | PRKD1 | 0.74582236 |
71 | INSR | 0.74442871 |
72 | OBSCN | 0.73269586 |
73 | PRKCH | 0.73102786 |
74 | NEK2 | 0.72574476 |
75 | MAP3K12 | 0.69693556 |
76 | ADRBK1 | 0.68872678 |
77 | NEK9 | 0.67270743 |
78 | SIK1 | 0.66426837 |
79 | MAP3K6 | 0.64658907 |
80 | PAK2 | 0.63196498 |
81 | SGK3 | 0.62070112 |
82 | BRD4 | 0.61430830 |
83 | TBK1 | 0.61169786 |
84 | EGFR | 0.60973554 |
85 | PAK3 | 0.59660853 |
86 | CDK12 | 0.58950130 |
87 | CDC42BPA | 0.58477372 |
88 | MTOR | 0.57730109 |
89 | RET | 0.57590652 |
90 | NEK1 | 0.57263246 |
91 | LMTK2 | 0.57007415 |
92 | ZAK | 0.56473136 |
93 | ABL2 | 0.55261731 |
94 | SGK2 | 0.52683162 |
95 | PIK3CA | 0.52326428 |
96 | SRC | 0.51492792 |
97 | FGFR4 | 0.51195431 |
98 | SCYL2 | 0.51058042 |
99 | PDPK1 | 0.50910000 |
100 | MAP2K1 | 0.50635137 |
101 | GSK3A | 0.49929416 |
102 | GRK1 | 0.49258199 |
103 | EIF2AK2 | 0.49196421 |
104 | MAP3K2 | 0.49059141 |
105 | JAK1 | 0.48653610 |
106 | TAOK1 | 0.47898189 |
107 | CLK1 | 0.47315096 |
108 | CAMKK1 | 0.46032659 |
109 | STK39 | 0.45752876 |
110 | PRKCE | 0.45467027 |
111 | ROCK2 | 0.45344986 |
112 | JAK3 | 0.45282925 |
113 | PLK3 | 0.45058843 |
114 | MAP3K3 | 0.44940935 |
115 | ALK | 0.44063453 |
116 | MAPKAPK3 | 0.43644306 |
117 | ROCK1 | 0.43452191 |
118 | ABL1 | 0.43379978 |
119 | MKNK1 | 0.42053676 |
120 | ERN1 | 0.41000868 |
121 | EPHA3 | 0.40591087 |
122 | EPHB1 | 0.39419156 |
123 | NTRK2 | 0.39127234 |
124 | EPHA2 | 0.38918847 |
125 | AKT2 | 0.38381221 |
126 | STK24 | 0.37226484 |
127 | PIM2 | 0.36706340 |
128 | TYRO3 | 0.36538706 |
129 | TNIK | 0.36382969 |
130 | MAP3K7 | 0.35737198 |
131 | PLK2 | 0.35166032 |
132 | ARAF | 0.35158148 |
133 | MAP2K2 | 0.34949000 |
134 | CSNK1G1 | 0.34810629 |
135 | ZAP70 | 0.34284313 |
136 | CHUK | 0.34106009 |
137 | SIK3 | 0.33517794 |
138 | TRPM7 | 0.33221040 |
139 | FES | 0.33206544 |
140 | TEC | 0.32962293 |
141 | PRKD2 | 0.31205792 |
142 | CSK | 0.30914976 |
143 | KSR2 | 0.30693626 |
144 | MAPK15 | 0.28799845 |
145 | PRKCQ | 0.28288490 |
146 | MARK2 | 0.27369985 |
147 | RPS6KA4 | 0.27124265 |
148 | ERBB3 | 0.26913781 |
149 | MAP3K1 | 0.25375191 |
150 | MAP2K3 | 0.25146663 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Adherens junction_Homo sapiens_hsa04520 | 2.88775547 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.65121573 |
3 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.29171334 |
4 | Focal adhesion_Homo sapiens_hsa04510 | 2.14579029 |
5 | Lysosome_Homo sapiens_hsa04142 | 1.81536735 |
6 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.73355913 |
7 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.70186205 |
8 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.68115038 |
9 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.67619807 |
10 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.67065496 |
11 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.64045646 |
12 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.61980247 |
13 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.59430793 |
14 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.59410750 |
15 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.56575410 |
16 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.52325638 |
17 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.47233799 |
18 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.40043589 |
19 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.39478766 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.39276796 |
21 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.38979092 |
22 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.38205528 |
23 | Melanogenesis_Homo sapiens_hsa04916 | 1.34042391 |
24 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.25651125 |
25 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.22363634 |
26 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.21794631 |
27 | Amoebiasis_Homo sapiens_hsa05146 | 1.21153501 |
28 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.18383724 |
29 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.15895398 |
30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.15624867 |
31 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.14608826 |
32 | Platelet activation_Homo sapiens_hsa04611 | 1.13534959 |
33 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.12918879 |
34 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.12402956 |
35 | Tight junction_Homo sapiens_hsa04530 | 1.12314893 |
36 | Axon guidance_Homo sapiens_hsa04360 | 1.12271014 |
37 | Glioma_Homo sapiens_hsa05214 | 1.11868546 |
38 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.11486136 |
39 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.11202022 |
40 | Other glycan degradation_Homo sapiens_hsa00511 | 1.10810488 |
41 | Pertussis_Homo sapiens_hsa05133 | 1.09958562 |
42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.08432532 |
43 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.08344422 |
44 | Ras signaling pathway_Homo sapiens_hsa04014 | 1.08135922 |
45 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.08128422 |
46 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.06735700 |
47 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.06473391 |
48 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06046686 |
49 | Legionellosis_Homo sapiens_hsa05134 | 1.04901875 |
50 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.04753159 |
51 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.02884345 |
52 | Prostate cancer_Homo sapiens_hsa05215 | 1.02353073 |
53 | Melanoma_Homo sapiens_hsa05218 | 1.00483828 |
54 | Pathways in cancer_Homo sapiens_hsa05200 | 0.99856267 |
55 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.99671992 |
56 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.99102458 |
57 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.98890000 |
58 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.98761963 |
59 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.96030862 |
60 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.95927218 |
61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.94103070 |
62 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.94081672 |
63 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.94011461 |
64 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.93642827 |
65 | Bile secretion_Homo sapiens_hsa04976 | 0.93251434 |
66 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.92156988 |
67 | Gap junction_Homo sapiens_hsa04540 | 0.92136157 |
68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92085896 |
69 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.90039782 |
70 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.88912547 |
71 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.88591039 |
72 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.87550171 |
73 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85836588 |
74 | Endocytosis_Homo sapiens_hsa04144 | 0.85774991 |
75 | Salivary secretion_Homo sapiens_hsa04970 | 0.84502422 |
76 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.83153006 |
77 | Viral myocarditis_Homo sapiens_hsa05416 | 0.81944331 |
78 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.81812969 |
79 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.81497900 |
80 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.80628658 |
81 | Long-term depression_Homo sapiens_hsa04730 | 0.80594744 |
82 | Renin secretion_Homo sapiens_hsa04924 | 0.79816147 |
83 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.79301285 |
84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.78504293 |
85 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77425787 |
86 | Circadian rhythm_Homo sapiens_hsa04710 | 0.77262147 |
87 | Insulin resistance_Homo sapiens_hsa04931 | 0.76667128 |
88 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.76525660 |
89 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.76155302 |
90 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.75981276 |
91 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.75290062 |
92 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.74827871 |
93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.74320202 |
94 | Long-term potentiation_Homo sapiens_hsa04720 | 0.72682933 |
95 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.72630664 |
96 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.72548741 |
97 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.72449746 |
98 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.71530010 |
99 | Mineral absorption_Homo sapiens_hsa04978 | 0.71527107 |
100 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.69631923 |
101 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.69273476 |
102 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.67686448 |
103 | Bladder cancer_Homo sapiens_hsa05219 | 0.66676966 |
104 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.66071257 |
105 | Endometrial cancer_Homo sapiens_hsa05213 | 0.65670271 |
106 | Thyroid cancer_Homo sapiens_hsa05216 | 0.64492434 |
107 | Insulin secretion_Homo sapiens_hsa04911 | 0.64377775 |
108 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.63121548 |
109 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.63029430 |
110 | Circadian entrainment_Homo sapiens_hsa04713 | 0.62768780 |
111 | Measles_Homo sapiens_hsa05162 | 0.62714571 |
112 | Phagosome_Homo sapiens_hsa04145 | 0.62389153 |
113 | Shigellosis_Homo sapiens_hsa05131 | 0.62123862 |
114 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61991747 |
115 | Malaria_Homo sapiens_hsa05144 | 0.61702576 |
116 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.60149390 |
117 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.59308720 |
118 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.58968002 |
119 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58403399 |
120 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57997669 |
121 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.56630818 |
122 | Salmonella infection_Homo sapiens_hsa05132 | 0.56496100 |
123 | HTLV-I infection_Homo sapiens_hsa05166 | 0.56397467 |
124 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.55904906 |
125 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.55405632 |
126 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.54708668 |
127 | Hepatitis C_Homo sapiens_hsa05160 | 0.53393220 |
128 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51343060 |
129 | Basal transcription factors_Homo sapiens_hsa03022 | 0.50881594 |
130 | Influenza A_Homo sapiens_hsa05164 | 0.49781513 |
131 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.47644099 |
132 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.46600719 |
133 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44266865 |
134 | Apoptosis_Homo sapiens_hsa04210 | 0.43512731 |
135 | Tuberculosis_Homo sapiens_hsa05152 | 0.41722044 |
136 | Hepatitis B_Homo sapiens_hsa05161 | 0.40075455 |
137 | Leishmaniasis_Homo sapiens_hsa05140 | 0.39923755 |
138 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.38514477 |