Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 5.65220763 |
2 | mitotic sister chromatid cohesion (GO:0007064) | 5.34024110 |
3 | nuclear pore organization (GO:0006999) | 5.01629018 |
4 | pre-miRNA processing (GO:0031054) | 4.39184711 |
5 | pore complex assembly (GO:0046931) | 4.27576285 |
6 | piRNA metabolic process (GO:0034587) | 4.24320697 |
7 | regulation of histone H3-K27 methylation (GO:0061085) | 4.16170523 |
8 | gene silencing by RNA (GO:0031047) | 4.03638028 |
9 | regulation of RNA export from nucleus (GO:0046831) | 4.01051235 |
10 | negative regulation of histone methylation (GO:0031061) | 3.99877835 |
11 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.95685610 |
12 | regulation of histone H3-K9 methylation (GO:0051570) | 3.94842909 |
13 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.67504774 |
14 | synaptonemal complex assembly (GO:0007130) | 3.66513220 |
15 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.64732488 |
16 | gene silencing (GO:0016458) | 3.59067559 |
17 | heterochromatin organization (GO:0070828) | 3.58029013 |
18 | histone H3-K9 methylation (GO:0051567) | 3.52697739 |
19 | male meiosis (GO:0007140) | 3.50749628 |
20 | histone lysine demethylation (GO:0070076) | 3.49622586 |
21 | histone H3-K4 trimethylation (GO:0080182) | 3.49172535 |
22 | histone H3-K4 methylation (GO:0051568) | 3.47534110 |
23 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.47509057 |
24 | mitotic chromosome condensation (GO:0007076) | 3.46032775 |
25 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.44099698 |
26 | mitotic nuclear envelope disassembly (GO:0007077) | 3.43972040 |
27 | sister chromatid segregation (GO:0000819) | 3.38939325 |
28 | synaptonemal complex organization (GO:0070193) | 3.37333873 |
29 | protein localization to chromosome, centromeric region (GO:0071459) | 3.37270279 |
30 | peptidyl-lysine dimethylation (GO:0018027) | 3.34598979 |
31 | protein-DNA complex disassembly (GO:0032986) | 3.31622040 |
32 | nucleosome disassembly (GO:0006337) | 3.31622040 |
33 | stress granule assembly (GO:0034063) | 3.31228147 |
34 | histone demethylation (GO:0016577) | 3.29311304 |
35 | RNA stabilization (GO:0043489) | 3.28800591 |
36 | mRNA stabilization (GO:0048255) | 3.28800591 |
37 | nuclear envelope disassembly (GO:0051081) | 3.25189542 |
38 | membrane disassembly (GO:0030397) | 3.25189542 |
39 | translesion synthesis (GO:0019985) | 3.25075252 |
40 | DNA unwinding involved in DNA replication (GO:0006268) | 3.21090481 |
41 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.20484569 |
42 | protein localization to kinetochore (GO:0034501) | 3.20184236 |
43 | histone H3-K9 modification (GO:0061647) | 3.18132094 |
44 | dosage compensation (GO:0007549) | 3.17627530 |
45 | adherens junction assembly (GO:0034333) | 3.16554487 |
46 | positive regulation of histone deacetylation (GO:0031065) | 3.11821000 |
47 | DNA alkylation (GO:0006305) | 3.10353007 |
48 | DNA methylation (GO:0006306) | 3.10353007 |
49 | sister chromatid cohesion (GO:0007062) | 3.09956293 |
50 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.09603762 |
51 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.09603762 |
52 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.09603762 |
53 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.09395373 |
54 | regulation of sister chromatid cohesion (GO:0007063) | 3.09198204 |
55 | chromatin assembly (GO:0031497) | 3.09187696 |
56 | mitotic sister chromatid segregation (GO:0000070) | 3.09062172 |
57 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.07134546 |
58 | histone lysine methylation (GO:0034968) | 3.06958486 |
59 | peptidyl-lysine trimethylation (GO:0018023) | 3.06874533 |
60 | embryonic camera-type eye morphogenesis (GO:0048596) | 3.06500540 |
61 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.06374865 |
62 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.06287411 |
63 | DNA duplex unwinding (GO:0032508) | 3.05534772 |
64 | regulation of centriole replication (GO:0046599) | 3.05430448 |
65 | NLS-bearing protein import into nucleus (GO:0006607) | 3.03660761 |
66 | DNA geometric change (GO:0032392) | 3.03580510 |
67 | positive regulation of gene expression, epigenetic (GO:0045815) | 3.03309012 |
68 | focal adhesion assembly (GO:0048041) | 2.99057430 |
69 | cell-substrate adherens junction assembly (GO:0007045) | 2.99057430 |
70 | neural tube development (GO:0021915) | 2.97621661 |
71 | DNA packaging (GO:0006323) | 2.97075252 |
72 | chromosome condensation (GO:0030261) | 2.96026219 |
73 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 2.93892996 |
74 | regulation of DNA endoreduplication (GO:0032875) | 2.91977285 |
75 | regulation of chromatin binding (GO:0035561) | 2.90999544 |
76 | histone H3-K36 demethylation (GO:0070544) | 2.90653837 |
77 | DNA methylation involved in gamete generation (GO:0043046) | 2.90613832 |
78 | positive regulation of chromosome segregation (GO:0051984) | 2.87413826 |
79 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.87050859 |
80 | protein dealkylation (GO:0008214) | 2.86889120 |
81 | protein demethylation (GO:0006482) | 2.86889120 |
82 | regulation of histone methylation (GO:0031060) | 2.86585035 |
83 | camera-type eye morphogenesis (GO:0048593) | 2.85537369 |
84 | chromatin silencing (GO:0006342) | 2.85536334 |
85 | DNA conformation change (GO:0071103) | 2.84572068 |
86 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.82909976 |
87 | chromosome organization involved in meiosis (GO:0070192) | 2.82243483 |
88 | regulation of meiosis I (GO:0060631) | 2.80144518 |
89 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.79913322 |
90 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.79665145 |
91 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.79190136 |
92 | embryonic eye morphogenesis (GO:0048048) | 2.78496515 |
93 | histone deubiquitination (GO:0016578) | 2.77904590 |
94 | meiotic chromosome segregation (GO:0045132) | 2.77642797 |
95 | semaphorin-plexin signaling pathway (GO:0071526) | 2.76386507 |
96 | establishment of spindle orientation (GO:0051294) | 2.74782631 |
97 | meiotic nuclear division (GO:0007126) | 2.74469408 |
98 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.74179288 |
99 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.74179288 |
100 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.73940158 |
101 | protein localization to chromosome (GO:0034502) | 2.73765696 |
102 | eye morphogenesis (GO:0048592) | 2.73723242 |
103 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.73614259 |
104 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.72662733 |
105 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.72662733 |
106 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.72060546 |
107 | peptidyl-lysine methylation (GO:0018022) | 2.71397324 |
108 | corticosteroid receptor signaling pathway (GO:0031958) | 2.70905612 |
109 | histone H4-K12 acetylation (GO:0043983) | 2.70831406 |
110 | response to epidermal growth factor (GO:0070849) | 2.70798597 |
111 | regulation of DNA damage checkpoint (GO:2000001) | 2.70464681 |
112 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.69441221 |
113 | negative regulation of histone modification (GO:0031057) | 2.69420524 |
114 | histone H4-K16 acetylation (GO:0043984) | 2.69213974 |
115 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.68786092 |
116 | establishment of spindle localization (GO:0051293) | 2.68246954 |
117 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.68068238 |
118 | negative regulation of DNA repair (GO:0045738) | 2.68028480 |
119 | regulation of mitotic spindle organization (GO:0060236) | 2.67865562 |
120 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.67361001 |
121 | histone mRNA catabolic process (GO:0071044) | 2.67307304 |
122 | histone methylation (GO:0016571) | 2.66105363 |
123 | convergent extension (GO:0060026) | 2.64981020 |
124 | histone H3-K9 demethylation (GO:0033169) | 2.64815591 |
125 | regulation of histone H3-K4 methylation (GO:0051569) | 2.64811904 |
126 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.64744137 |
127 | nuclear envelope organization (GO:0006998) | 2.64596108 |
128 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.64146227 |
129 | negative regulation of mRNA metabolic process (GO:1903312) | 2.63627055 |
130 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.63380254 |
131 | positive thymic T cell selection (GO:0045059) | 2.62333124 |
132 | DNA topological change (GO:0006265) | 2.59753575 |
133 | mannose metabolic process (GO:0006013) | 2.59542180 |
134 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.59044346 |
135 | paraxial mesoderm development (GO:0048339) | 2.57651294 |
136 | peptidyl-threonine phosphorylation (GO:0018107) | 2.57209977 |
137 | positive regulation by host of viral transcription (GO:0043923) | 2.53430208 |
138 | N-terminal protein amino acid acetylation (GO:0006474) | 2.52084534 |
139 | DNA synthesis involved in DNA repair (GO:0000731) | 2.51788812 |
140 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.51633836 |
141 | apoptotic process involved in morphogenesis (GO:0060561) | 2.49690873 |
142 | establishment of mitotic spindle localization (GO:0040001) | 2.49310706 |
143 | cell-substrate junction assembly (GO:0007044) | 2.45455616 |
144 | negative regulation of myotube differentiation (GO:0010832) | 2.45252188 |
145 | protein export from nucleus (GO:0006611) | 2.45050634 |
146 | peptidyl-threonine modification (GO:0018210) | 2.44355223 |
147 | coronary vasculature morphogenesis (GO:0060977) | 2.43827108 |
148 | heart morphogenesis (GO:0003007) | 2.43406477 |
149 | establishment of mitotic spindle orientation (GO:0000132) | 2.40617114 |
150 | establishment of nucleus localization (GO:0040023) | 2.40425682 |
151 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.39080464 |
152 | regulation of ARF GTPase activity (GO:0032312) | 2.38955857 |
153 | embryonic process involved in female pregnancy (GO:0060136) | 2.38820914 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.92025870 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.84270250 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.14887351 |
4 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.82545722 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 3.78948681 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.25868873 |
7 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.90628482 |
8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.70589402 |
9 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.61046969 |
10 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.56755542 |
11 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.56666740 |
12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.43106078 |
13 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.39214807 |
14 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.34575563 |
15 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.29654053 |
16 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.26001826 |
17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.18163833 |
18 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.17122975 |
19 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.17116141 |
20 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.10063329 |
21 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.05692310 |
22 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.04774592 |
23 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.04187928 |
24 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.97720816 |
25 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.97243740 |
26 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.93354424 |
27 | UTX_26944678_Chip-Seq_JUKART_Human | 1.91438256 |
28 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.89860932 |
29 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.81797398 |
30 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.80413192 |
31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.78362112 |
32 | MAF_26560356_Chip-Seq_TH1_Human | 1.78283694 |
33 | MYB_26560356_Chip-Seq_TH1_Human | 1.73268267 |
34 | MYB_26560356_Chip-Seq_TH2_Human | 1.71698853 |
35 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.70395432 |
36 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.68744617 |
37 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.67083026 |
38 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.61303010 |
39 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.59282093 |
40 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.58060918 |
41 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56588359 |
42 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.55029580 |
43 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.52659029 |
44 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.49824628 |
45 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.47429267 |
46 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.46383537 |
47 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.42527038 |
48 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.41963122 |
49 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.41963122 |
50 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.41963122 |
51 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.39948848 |
52 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.39414552 |
53 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.37657647 |
54 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.34440197 |
55 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.34083114 |
56 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.32702390 |
57 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.32522955 |
58 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.29360841 |
59 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.29240962 |
60 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.28648242 |
61 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.26734866 |
62 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.26295080 |
63 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.26270179 |
64 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.25566887 |
65 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.25040705 |
66 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.24651688 |
67 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.24177331 |
68 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.23973291 |
69 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.23148945 |
70 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.21976766 |
71 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.21815582 |
72 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.21627988 |
73 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.21340632 |
74 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.20890229 |
75 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.20770713 |
76 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.19907856 |
77 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19391452 |
78 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.17969293 |
79 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.17482363 |
80 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.16439008 |
81 | MAF_26560356_Chip-Seq_TH2_Human | 1.16107188 |
82 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.14771356 |
83 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.13324185 |
84 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.12669947 |
85 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.11554543 |
86 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.11549132 |
87 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.11516415 |
88 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.11193321 |
89 | SPI1_23127762_ChIP-Seq_K562_Human | 1.09241654 |
90 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.08768470 |
91 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06179527 |
92 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.05803358 |
93 | * SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.05615761 |
94 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.04352319 |
95 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.03996682 |
96 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02982906 |
97 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.02744549 |
98 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01687895 |
99 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.00294237 |
100 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.00064163 |
101 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.99984674 |
102 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.99257524 |
103 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.99093870 |
104 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.98903933 |
105 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.98449482 |
106 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.98045789 |
107 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.96163481 |
108 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.93177401 |
109 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.92987797 |
110 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.92026063 |
111 | P68_20966046_ChIP-Seq_HELA_Human | 0.91823008 |
112 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.91623639 |
113 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91565214 |
114 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.91524724 |
115 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.91398455 |
116 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.90014794 |
117 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 0.89241171 |
118 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.89016534 |
119 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88780560 |
120 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.88548135 |
121 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.88254590 |
122 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.88250736 |
123 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.87973786 |
124 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.87277407 |
125 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.85608506 |
126 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85596016 |
127 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.85315667 |
128 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84979676 |
129 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.84584774 |
130 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.84522403 |
131 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.83574735 |
132 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.81682132 |
133 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.80872909 |
134 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.80540557 |
135 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.80486085 |
136 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.79520254 |
137 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.79149428 |
138 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.78237841 |
139 | * KDM2B_26808549_Chip-Seq_K562_Human | 0.76711827 |
140 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76410980 |
141 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.76159497 |
142 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.76066296 |
143 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.75725033 |
144 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.75016591 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008877_abnormal_DNA_methylation | 4.03353146 |
2 | MP0000569_abnormal_digit_pigmentation | 3.47890695 |
3 | MP0010094_abnormal_chromosome_stability | 3.02443471 |
4 | MP0005409_darkened_coat_color | 3.00150698 |
5 | MP0008057_abnormal_DNA_replication | 2.98317910 |
6 | MP0003111_abnormal_nucleus_morphology | 2.93633674 |
7 | MP0005076_abnormal_cell_differentiation | 2.92694957 |
8 | MP0010352_gastrointestinal_tract_polyps | 2.62517089 |
9 | MP0003077_abnormal_cell_cycle | 2.51671564 |
10 | MP0002396_abnormal_hematopoietic_system | 2.51400561 |
11 | MP0005410_abnormal_fertilization | 2.42025969 |
12 | MP0002009_preneoplasia | 2.33105644 |
13 | MP0010307_abnormal_tumor_latency | 2.30660120 |
14 | MP0002249_abnormal_larynx_morphology | 2.28785947 |
15 | * MP0004808_abnormal_hematopoietic_stem | 2.20819835 |
16 | MP0003787_abnormal_imprinting | 2.07292274 |
17 | MP0000566_synostosis | 1.96976950 |
18 | MP0002653_abnormal_ependyma_morphology | 1.90908026 |
19 | MP0003693_abnormal_embryo_hatching | 1.90113001 |
20 | MP0010030_abnormal_orbit_morphology | 1.85811983 |
21 | MP0001929_abnormal_gametogenesis | 1.84775270 |
22 | MP0003300_gastrointestinal_ulcer | 1.84689460 |
23 | MP0003763_abnormal_thymus_physiology | 1.83254309 |
24 | MP0004957_abnormal_blastocyst_morpholog | 1.79641042 |
25 | MP0008058_abnormal_DNA_repair | 1.78676875 |
26 | MP0000350_abnormal_cell_proliferation | 1.76519307 |
27 | MP0008007_abnormal_cellular_replicative | 1.75091566 |
28 | MP0004185_abnormal_adipocyte_glucose | 1.73590443 |
29 | * MP0001730_embryonic_growth_arrest | 1.72850993 |
30 | MP0004233_abnormal_muscle_weight | 1.72846328 |
31 | * MP0009278_abnormal_bone_marrow | 1.72786879 |
32 | MP0003121_genomic_imprinting | 1.69982596 |
33 | MP0000703_abnormal_thymus_morphology | 1.68670443 |
34 | MP0002210_abnormal_sex_determination | 1.66645310 |
35 | MP0001348_abnormal_lacrimal_gland | 1.63828629 |
36 | MP0000537_abnormal_urethra_morphology | 1.61901946 |
37 | MP0004197_abnormal_fetal_growth/weight/ | 1.59044806 |
38 | MP0008961_abnormal_basal_metabolism | 1.56514669 |
39 | MP0005380_embryogenesis_phenotype | 1.55851856 |
40 | MP0001672_abnormal_embryogenesis/_devel | 1.55851856 |
41 | MP0003698_abnormal_male_reproductive | 1.55460910 |
42 | * MP0002398_abnormal_bone_marrow | 1.53765062 |
43 | MP0003984_embryonic_growth_retardation | 1.53480883 |
44 | MP0002084_abnormal_developmental_patter | 1.52640822 |
45 | MP0002088_abnormal_embryonic_growth/wei | 1.50650156 |
46 | MP0003303_peritoneal_inflammation | 1.49385894 |
47 | MP0002089_abnormal_postnatal_growth/wei | 1.46343841 |
48 | MP0003705_abnormal_hypodermis_morpholog | 1.45734754 |
49 | * MP0001545_abnormal_hematopoietic_system | 1.44277709 |
50 | * MP0005397_hematopoietic_system_phenotyp | 1.44277709 |
51 | MP0002086_abnormal_extraembryonic_tissu | 1.42952356 |
52 | MP0002166_altered_tumor_susceptibility | 1.42233213 |
53 | MP0004858_abnormal_nervous_system | 1.42097684 |
54 | MP0001145_abnormal_male_reproductive | 1.38701974 |
55 | MP0000678_abnormal_parathyroid_gland | 1.37469655 |
56 | * MP0002085_abnormal_embryonic_tissue | 1.36527305 |
57 | MP0001697_abnormal_embryo_size | 1.36380767 |
58 | MP0003942_abnormal_urinary_system | 1.35945643 |
59 | MP0000733_abnormal_muscle_development | 1.30012553 |
60 | MP0001800_abnormal_humoral_immune | 1.27605332 |
61 | MP0002116_abnormal_craniofacial_bone | 1.25774208 |
62 | MP0000685_abnormal_immune_system | 1.25463941 |
63 | MP0003890_abnormal_embryonic-extraembry | 1.24208930 |
64 | * MP0003861_abnormal_nervous_system | 1.23172079 |
65 | MP0001873_stomach_inflammation | 1.22474106 |
66 | MP0008995_early_reproductive_senescence | 1.22052100 |
67 | MP0003385_abnormal_body_wall | 1.21020832 |
68 | MP0001849_ear_inflammation | 1.20534155 |
69 | MP0010630_abnormal_cardiac_muscle | 1.20459679 |
70 | MP0000653_abnormal_sex_gland | 1.20242144 |
71 | MP0003453_abnormal_keratinocyte_physiol | 1.19193005 |
72 | MP0000490_abnormal_crypts_of | 1.18343835 |
73 | MP0001915_intracranial_hemorrhage | 1.17642343 |
74 | MP0002722_abnormal_immune_system | 1.16965711 |
75 | * MP0002080_prenatal_lethality | 1.15932996 |
76 | MP0002019_abnormal_tumor_incidence | 1.14328157 |
77 | MP0005666_abnormal_adipose_tissue | 1.14021619 |
78 | MP0002006_tumorigenesis | 1.13352087 |
79 | MP0000313_abnormal_cell_death | 1.12854989 |
80 | MP0003283_abnormal_digestive_organ | 1.12049538 |
81 | MP0003115_abnormal_respiratory_system | 1.11717593 |
82 | MP0003045_fibrosis | 1.11231213 |
83 | MP0003123_paternal_imprinting | 1.11105495 |
84 | MP0000689_abnormal_spleen_morphology | 1.10200061 |
85 | MP0000716_abnormal_immune_system | 1.06893250 |
86 | MP0002114_abnormal_axial_skeleton | 1.03405407 |
87 | MP0001299_abnormal_eye_distance/ | 1.02106748 |
88 | MP0002796_impaired_skin_barrier | 1.01325722 |
89 | MP0009703_decreased_birth_body | 1.00145526 |
90 | MP0005174_abnormal_tail_pigmentation | 0.99649663 |
91 | MP0002925_abnormal_cardiovascular_devel | 0.98862041 |
92 | MP0000534_abnormal_ureter_morphology | 0.98397516 |
93 | MP0002161_abnormal_fertility/fecundity | 0.97946190 |
94 | MP0001293_anophthalmia | 0.97308327 |
95 | * MP0002429_abnormal_blood_cell | 0.96942467 |
96 | MP0002405_respiratory_system_inflammati | 0.96666627 |
97 | MP0002877_abnormal_melanocyte_morpholog | 0.95365843 |
98 | MP0004264_abnormal_extraembryonic_tissu | 0.95286206 |
99 | MP0000579_abnormal_nail_morphology | 0.95275066 |
100 | MP0002420_abnormal_adaptive_immunity | 0.95129807 |
101 | MP0009053_abnormal_anal_canal | 0.94674949 |
102 | MP0002081_perinatal_lethality | 0.94531951 |
103 | MP0001819_abnormal_immune_cell | 0.93556662 |
104 | MP0003935_abnormal_craniofacial_develop | 0.93313482 |
105 | MP0005451_abnormal_body_composition | 0.93193220 |
106 | MP0002452_abnormal_antigen_presenting | 0.93100628 |
107 | MP0001835_abnormal_antigen_presentation | 0.92624059 |
108 | MP0002092_abnormal_eye_morphology | 0.91360731 |
109 | MP0001790_abnormal_immune_system | 0.91120039 |
110 | MP0005387_immune_system_phenotype | 0.91120039 |
111 | MP0003937_abnormal_limbs/digits/tail_de | 0.90929053 |
112 | MP0009672_abnormal_birth_weight | 0.89631183 |
113 | MP0003755_abnormal_palate_morphology | 0.88225543 |
114 | MP0001346_abnormal_lacrimal_gland | 0.87450153 |
115 | MP0003786_premature_aging | 0.86828811 |
116 | MP0005257_abnormal_intraocular_pressure | 0.86655247 |
117 | MP0000428_abnormal_craniofacial_morphol | 0.86118224 |
118 | MP0005375_adipose_tissue_phenotype | 0.85155489 |
119 | MP0002723_abnormal_immune_serum | 0.84347634 |
120 | MP0003943_abnormal_hepatobiliary_system | 0.83386245 |
121 | MP0000383_abnormal_hair_follicle | 0.83259699 |
122 | MP0004381_abnormal_hair_follicle | 0.82810037 |
123 | MP0003566_abnormal_cell_adhesion | 0.82183345 |
124 | MP0005671_abnormal_response_to | 0.82168765 |
125 | MP0005621_abnormal_cell_physiology | 0.81525026 |
126 | MP0005623_abnormal_meninges_morphology | 0.81137791 |
127 | MP0004947_skin_inflammation | 0.81118778 |
128 | MP0005384_cellular_phenotype | 0.80725953 |
129 | MP0003866_abnormal_defecation | 0.79682027 |
130 | MP0000462_abnormal_digestive_system | 0.79383121 |
131 | MP0000266_abnormal_heart_morphology | 0.79129708 |
132 | MP0008932_abnormal_embryonic_tissue | 0.78913647 |
133 | MP0003091_abnormal_cell_migration | 0.77881447 |
134 | MP0002108_abnormal_muscle_morphology | 0.77735533 |
135 | MP0000432_abnormal_head_morphology | 0.77326723 |
136 | MP0001286_abnormal_eye_development | 0.76530978 |
137 | MP0002060_abnormal_skin_morphology | 0.76368180 |
138 | MP0010368_abnormal_lymphatic_system | 0.76086725 |
139 | MP0002928_abnormal_bile_duct | 0.75654371 |
140 | MP0006138_congestive_heart_failure | 0.75357209 |
141 | MP0004087_abnormal_muscle_fiber | 0.74117696 |
142 | MP0001784_abnormal_fluid_regulation | 0.73830544 |
143 | MP0002697_abnormal_eye_size | 0.73599350 |
144 | MP0002932_abnormal_joint_morphology | 0.73562412 |
145 | MP0006292_abnormal_olfactory_placode | 0.73136889 |
146 | MP0010155_abnormal_intestine_physiology | 0.72536258 |
147 | MP0000759_abnormal_skeletal_muscle | 0.71374625 |
148 | MP0002970_abnormal_white_adipose | 0.71133540 |
149 | MP0001340_abnormal_eyelid_morphology | 0.70862011 |
150 | MP0009931_abnormal_skin_appearance | 0.70840402 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of the fingertips (HP:0001211) | 4.37478218 |
2 | Obstructive sleep apnea (HP:0002870) | 4.08619257 |
3 | Volvulus (HP:0002580) | 3.41102999 |
4 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.21242563 |
5 | Short 4th metacarpal (HP:0010044) | 3.21242563 |
6 | Heterotopia (HP:0002282) | 3.08266316 |
7 | Broad face (HP:0000283) | 3.07591133 |
8 | Hyperacusis (HP:0010780) | 3.05414451 |
9 | Long eyelashes (HP:0000527) | 2.92983536 |
10 | Increased nuchal translucency (HP:0010880) | 2.81575986 |
11 | Nasal polyposis (HP:0100582) | 2.73792041 |
12 | Shallow orbits (HP:0000586) | 2.71631444 |
13 | Prominent nose (HP:0000448) | 2.69690029 |
14 | Flat acetabular roof (HP:0003180) | 2.63340494 |
15 | Ectopic kidney (HP:0000086) | 2.62056041 |
16 | Trigonocephaly (HP:0000243) | 2.59753645 |
17 | Vertebral arch anomaly (HP:0008438) | 2.51679315 |
18 | Disproportionate tall stature (HP:0001519) | 2.51298238 |
19 | Macroorchidism (HP:0000053) | 2.49147517 |
20 | Renovascular hypertension (HP:0100817) | 2.47597897 |
21 | High pitched voice (HP:0001620) | 2.43396881 |
22 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.42733582 |
23 | Abnormality of the aortic arch (HP:0012303) | 2.40187214 |
24 | Ependymoma (HP:0002888) | 2.38263539 |
25 | Dysmetric saccades (HP:0000641) | 2.37867152 |
26 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.31580347 |
27 | Ulnar bowing (HP:0003031) | 2.31296806 |
28 | Abnormality of the astrocytes (HP:0100707) | 2.29321726 |
29 | Astrocytoma (HP:0009592) | 2.29321726 |
30 | Truncal obesity (HP:0001956) | 2.27853396 |
31 | Absent frontal sinuses (HP:0002688) | 2.27758543 |
32 | Elfin facies (HP:0004428) | 2.27548776 |
33 | Abnormality of the 4th metacarpal (HP:0010012) | 2.25528829 |
34 | High anterior hairline (HP:0009890) | 2.24906400 |
35 | Broad palm (HP:0001169) | 2.23356775 |
36 | Urethral obstruction (HP:0000796) | 2.21898095 |
37 | Chromsome breakage (HP:0040012) | 2.18692896 |
38 | Obsessive-compulsive behavior (HP:0000722) | 2.17962550 |
39 | Abnormality of the nasal mucosa (HP:0000433) | 2.17638164 |
40 | Recurrent bronchitis (HP:0002837) | 2.17088514 |
41 | Proximal placement of thumb (HP:0009623) | 2.16557779 |
42 | Acute myeloid leukemia (HP:0004808) | 2.15093335 |
43 | Neoplasm of the oral cavity (HP:0100649) | 2.14577405 |
44 | Medulloblastoma (HP:0002885) | 2.13929289 |
45 | Narrow palate (HP:0000189) | 2.12933413 |
46 | Deviation of the thumb (HP:0009603) | 2.11674657 |
47 | Renal duplication (HP:0000075) | 2.10540616 |
48 | Cerebral aneurysm (HP:0004944) | 2.09731367 |
49 | Long palpebral fissure (HP:0000637) | 2.08838226 |
50 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.06761164 |
51 | Absent/shortened dynein arms (HP:0200106) | 2.06761164 |
52 | Abnormality of the lower motor neuron (HP:0002366) | 2.06709251 |
53 | Mitral valve prolapse (HP:0001634) | 2.06434937 |
54 | Pointed chin (HP:0000307) | 2.05695434 |
55 | Impulsivity (HP:0100710) | 2.04920387 |
56 | Abnormality of the columella (HP:0009929) | 2.04485857 |
57 | Sandal gap (HP:0001852) | 2.03729914 |
58 | Anal stenosis (HP:0002025) | 2.01673574 |
59 | Ankyloglossia (HP:0010296) | 2.00155442 |
60 | Overriding aorta (HP:0002623) | 1.99239080 |
61 | Persistence of primary teeth (HP:0006335) | 1.98406391 |
62 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.94741666 |
63 | Bronchomalacia (HP:0002780) | 1.94053322 |
64 | Patellar dislocation (HP:0002999) | 1.93856259 |
65 | Broad finger (HP:0001500) | 1.92974651 |
66 | Limited elbow extension (HP:0001377) | 1.92640210 |
67 | Arnold-Chiari malformation (HP:0002308) | 1.90958424 |
68 | Selective tooth agenesis (HP:0001592) | 1.90755733 |
69 | Glioma (HP:0009733) | 1.90274470 |
70 | Sparse lateral eyebrow (HP:0005338) | 1.89610611 |
71 | Recurrent viral infections (HP:0004429) | 1.89265860 |
72 | Deep palmar crease (HP:0006191) | 1.89070090 |
73 | Supernumerary ribs (HP:0005815) | 1.88449349 |
74 | Cutis marmorata (HP:0000965) | 1.87751644 |
75 | Basal cell carcinoma (HP:0002671) | 1.86827966 |
76 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.86431315 |
77 | T lymphocytopenia (HP:0005403) | 1.86050992 |
78 | Turricephaly (HP:0000262) | 1.85685415 |
79 | Abnormality of the carotid arteries (HP:0005344) | 1.84984276 |
80 | Bowel diverticulosis (HP:0005222) | 1.84814887 |
81 | Thin ribs (HP:0000883) | 1.84792997 |
82 | Bowel incontinence (HP:0002607) | 1.83346457 |
83 | Increased density of long bones (HP:0006392) | 1.83173788 |
84 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.82523349 |
85 | Deep philtrum (HP:0002002) | 1.81762998 |
86 | Low anterior hairline (HP:0000294) | 1.81427438 |
87 | Advanced eruption of teeth (HP:0006288) | 1.81333516 |
88 | Skull defect (HP:0001362) | 1.80332761 |
89 | Asymmetry of the thorax (HP:0001555) | 1.80273858 |
90 | Protrusio acetabuli (HP:0003179) | 1.79961931 |
91 | Short phalanx of the thumb (HP:0009660) | 1.78995360 |
92 | Genetic anticipation (HP:0003743) | 1.78800622 |
93 | Recurrent otitis media (HP:0000403) | 1.78785526 |
94 | Precocious puberty (HP:0000826) | 1.78620886 |
95 | Spinal cord lesions (HP:0100561) | 1.78196505 |
96 | Syringomyelia (HP:0003396) | 1.78196505 |
97 | Abnormality of the parietal bone (HP:0002696) | 1.78109831 |
98 | Abnormality of chromosome stability (HP:0003220) | 1.77964918 |
99 | Bronchitis (HP:0012387) | 1.76142180 |
100 | Cafe-au-lait spot (HP:0000957) | 1.75262217 |
101 | Dislocated radial head (HP:0003083) | 1.75138500 |
102 | Broad distal phalanx of finger (HP:0009836) | 1.74555610 |
103 | Spina bifida occulta (HP:0003298) | 1.74458514 |
104 | Abnormality of the thoracic spine (HP:0100711) | 1.73755903 |
105 | Germ cell neoplasia (HP:0100728) | 1.72719595 |
106 | Broad thumb (HP:0011304) | 1.72086937 |
107 | Neoplasm of striated muscle (HP:0009728) | 1.71294151 |
108 | Acute lymphatic leukemia (HP:0006721) | 1.69896599 |
109 | Papillary thyroid carcinoma (HP:0002895) | 1.69864011 |
110 | Abnormality of the humeroradial joint (HP:0100744) | 1.69404901 |
111 | Distal upper limb amyotrophy (HP:0007149) | 1.68078393 |
112 | Upper limb amyotrophy (HP:0009129) | 1.68078393 |
113 | Natal tooth (HP:0000695) | 1.68036295 |
114 | Abnormality of the radial head (HP:0003995) | 1.68031258 |
115 | Flat cornea (HP:0007720) | 1.68007955 |
116 | Abnormality involving the epiphyses of the upper limbs (HP:0003839) | 1.67467418 |
117 | Mitral regurgitation (HP:0001653) | 1.66985463 |
118 | Skin tags (HP:0010609) | 1.66529690 |
119 | Myelodysplasia (HP:0002863) | 1.65839914 |
120 | Laryngomalacia (HP:0001601) | 1.65611262 |
121 | Broad phalanx (HP:0006009) | 1.65569871 |
122 | Abnormal vertebral ossification (HP:0100569) | 1.65185581 |
123 | Abnormality of the intervertebral disk (HP:0005108) | 1.64848059 |
124 | Abnormality of oral frenula (HP:0000190) | 1.63925411 |
125 | Abnormality of T cell number (HP:0011839) | 1.63600005 |
126 | Abnormality of the epiphyses of the hand (HP:0005924) | 1.63206260 |
127 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.61865230 |
128 | Gastrointestinal carcinoma (HP:0002672) | 1.61865230 |
129 | Megalocornea (HP:0000485) | 1.61701110 |
130 | Abnormal large intestine physiology (HP:0012700) | 1.61503743 |
131 | Insomnia (HP:0100785) | 1.61417642 |
132 | Abnormal number of incisors (HP:0011064) | 1.60667735 |
133 | Hypoplasia of the maxilla (HP:0000327) | 1.60628070 |
134 | Broad long bones (HP:0005622) | 1.60454706 |
135 | Facial hemangioma (HP:0000329) | 1.60107006 |
136 | Joint laxity (HP:0001388) | 1.59867223 |
137 | Lip pit (HP:0100267) | 1.59460035 |
138 | Thick eyebrow (HP:0000574) | 1.58608603 |
139 | Abnormality of the calcaneus (HP:0008364) | 1.57625189 |
140 | Broad metatarsal (HP:0001783) | 1.57441866 |
141 | Self-mutilation (HP:0000742) | 1.55840817 |
142 | Annular pancreas (HP:0001734) | 1.54807356 |
143 | Depressed nasal tip (HP:0000437) | 1.54746416 |
144 | Bronchiectasis (HP:0002110) | 1.54661811 |
145 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.54567126 |
146 | Amyotrophic lateral sclerosis (HP:0007354) | 1.54060845 |
147 | Tracheomalacia (HP:0002779) | 1.53190045 |
148 | Attention deficit hyperactivity disorder (HP:0007018) | 1.53145164 |
149 | Smooth philtrum (HP:0000319) | 1.53108221 |
150 | Abnormality of incisor morphology (HP:0011063) | 1.52750106 |
151 | Gastrointestinal inflammation (HP:0004386) | 1.51525070 |
152 | Sacral dimple (HP:0000960) | 1.50252415 |
153 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.50036059 |
154 | Aortic aneurysm (HP:0004942) | 1.49907642 |
155 | Hypoplastic labia majora (HP:0000059) | 1.49803283 |
156 | Broad phalanges of the hand (HP:0009768) | 1.49484551 |
157 | Overlapping toe (HP:0001845) | 1.48703313 |
158 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.48570182 |
159 | Bicuspid aortic valve (HP:0001647) | 1.48313783 |
160 | Abnormality of chromosome segregation (HP:0002916) | 1.48173057 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 5.71188784 |
2 | EEF2K | 3.70538243 |
3 | SMG1 | 3.40502929 |
4 | MAP3K10 | 3.29338659 |
5 | CDC7 | 3.14784526 |
6 | ICK | 3.00424365 |
7 | NEK2 | 2.86682334 |
8 | BRD4 | 2.77918391 |
9 | CAMK1G | 2.48781717 |
10 | PRPF4B | 2.45883840 |
11 | CAMK1D | 2.38793594 |
12 | MAP4K1 | 2.10675970 |
13 | SIK2 | 1.69899182 |
14 | TRIB3 | 1.64977920 |
15 | LATS1 | 1.63003529 |
16 | STK10 | 1.61657740 |
17 | MTOR | 1.60717134 |
18 | ATR | 1.60234808 |
19 | STK3 | 1.57753428 |
20 | PKN2 | 1.54354045 |
21 | CDK9 | 1.49143004 |
22 | CDK4 | 1.43314156 |
23 | TTK | 1.40191682 |
24 | PRKD3 | 1.37789233 |
25 | PASK | 1.31024067 |
26 | CHEK1 | 1.28734424 |
27 | CDK6 | 1.22769857 |
28 | MAP3K13 | 1.19734540 |
29 | FGFR3 | 1.17730719 |
30 | PTK6 | 1.13705664 |
31 | TYRO3 | 1.10617851 |
32 | JAK3 | 1.09030995 |
33 | ATM | 1.08350591 |
34 | PNCK | 1.01069134 |
35 | STK4 | 1.00111193 |
36 | CDK7 | 0.98545852 |
37 | CHEK2 | 0.98308177 |
38 | RPS6KB2 | 0.97680829 |
39 | SIK1 | 0.95432657 |
40 | LATS2 | 0.94987968 |
41 | ALK | 0.93993703 |
42 | ERN1 | 0.93959546 |
43 | MAP3K9 | 0.92650045 |
44 | RIPK1 | 0.90528912 |
45 | PDK3 | 0.88284530 |
46 | PDK4 | 0.88284530 |
47 | FGFR4 | 0.86427540 |
48 | MELK | 0.86123016 |
49 | CDK2 | 0.85755909 |
50 | CHUK | 0.84119991 |
51 | PIM1 | 0.81616476 |
52 | RPS6KA4 | 0.80334586 |
53 | TYK2 | 0.78798948 |
54 | FGFR2 | 0.76525590 |
55 | PDGFRB | 0.75074262 |
56 | KSR2 | 0.74033716 |
57 | PDGFRA | 0.73820780 |
58 | MAP3K8 | 0.72920225 |
59 | BTK | 0.70940916 |
60 | WEE1 | 0.70774383 |
61 | PLK1 | 0.70359545 |
62 | RPS6KA2 | 0.69947188 |
63 | NLK | 0.69002089 |
64 | TTN | 0.68560245 |
65 | AURKB | 0.68342923 |
66 | GRK6 | 0.67941084 |
67 | MAP3K7 | 0.67852157 |
68 | JAK1 | 0.67222512 |
69 | CSF1R | 0.65757937 |
70 | MAPK10 | 0.65237408 |
71 | BRSK1 | 0.64537095 |
72 | RPS6KC1 | 0.64321677 |
73 | RPS6KL1 | 0.64321677 |
74 | MARK2 | 0.64172956 |
75 | BRSK2 | 0.64091704 |
76 | TESK1 | 0.63384545 |
77 | TAOK1 | 0.63066943 |
78 | SGK2 | 0.62906148 |
79 | * CDK1 | 0.61636762 |
80 | ITK | 0.61601746 |
81 | WNK1 | 0.61418936 |
82 | TAOK3 | 0.61006751 |
83 | SGK3 | 0.60918107 |
84 | ZAP70 | 0.60866006 |
85 | PTK2 | 0.60385661 |
86 | MAPK11 | 0.59558173 |
87 | HCK | 0.59185728 |
88 | CAMKK1 | 0.58978789 |
89 | CLK1 | 0.57785316 |
90 | TXK | 0.57301625 |
91 | DYRK1B | 0.55115538 |
92 | MAP3K4 | 0.55102374 |
93 | CDK3 | 0.55067286 |
94 | AKT3 | 0.55050327 |
95 | CAMK4 | 0.54917656 |
96 | EPHB1 | 0.54375167 |
97 | PAK2 | 0.54069944 |
98 | DYRK3 | 0.53919532 |
99 | * MAPK14 | 0.52755946 |
100 | CSK | 0.51611277 |
101 | HIPK2 | 0.50346822 |
102 | STK38 | 0.49789029 |
103 | PRKCH | 0.49707833 |
104 | PRKDC | 0.48849510 |
105 | PRKD2 | 0.48756896 |
106 | CSNK1D | 0.48081883 |
107 | GSK3B | 0.47668520 |
108 | FGFR1 | 0.47660528 |
109 | MET | 0.47500761 |
110 | MKNK2 | 0.47282925 |
111 | NEK9 | 0.47195682 |
112 | RPS6KA6 | 0.47167476 |
113 | TGFBR1 | 0.46030820 |
114 | MAPK1 | 0.45137489 |
115 | LRRK2 | 0.44940149 |
116 | MARK3 | 0.44866102 |
117 | SGK494 | 0.44491725 |
118 | SGK223 | 0.44491725 |
119 | RET | 0.44241291 |
120 | DMPK | 0.44161614 |
121 | MAPK8 | 0.43683213 |
122 | AKT1 | 0.43489523 |
123 | CDC42BPA | 0.42837717 |
124 | BMX | 0.41062538 |
125 | PAK4 | 0.40527476 |
126 | RPS6KA1 | 0.39899389 |
127 | PRKAA1 | 0.39658645 |
128 | MKNK1 | 0.39465869 |
129 | PLK4 | 0.39458821 |
130 | LCK | 0.38822596 |
131 | MAP2K3 | 0.38407592 |
132 | MAPK15 | 0.37990560 |
133 | NTRK1 | 0.37189950 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cell cycle_Homo sapiens_hsa04110 | 2.06310130 |
2 | Lysine degradation_Homo sapiens_hsa00310 | 1.99653488 |
3 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.99173529 |
4 | DNA replication_Homo sapiens_hsa03030 | 1.95665756 |
5 | RNA transport_Homo sapiens_hsa03013 | 1.79031875 |
6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77519534 |
7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.69226305 |
8 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.68803211 |
9 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.67586444 |
10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.66536893 |
11 | Mismatch repair_Homo sapiens_hsa03430 | 1.63438388 |
12 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.55416691 |
13 | Spliceosome_Homo sapiens_hsa03040 | 1.53660493 |
14 | Base excision repair_Homo sapiens_hsa03410 | 1.52902679 |
15 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.46816837 |
16 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.45902846 |
17 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.45877252 |
18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.45689872 |
19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.39749860 |
20 | Homologous recombination_Homo sapiens_hsa03440 | 1.35643912 |
21 | HTLV-I infection_Homo sapiens_hsa05166 | 1.35277243 |
22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.33507960 |
23 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.32242554 |
24 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.30096965 |
25 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.29864438 |
26 | Colorectal cancer_Homo sapiens_hsa05210 | 1.28862031 |
27 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.28304109 |
28 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.27224692 |
29 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.26661930 |
30 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.25790476 |
31 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.23303807 |
32 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.22196804 |
33 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.21781809 |
34 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.20362636 |
35 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.17723191 |
36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16185748 |
37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.15657401 |
38 | RNA degradation_Homo sapiens_hsa03018 | 1.13851281 |
39 | Measles_Homo sapiens_hsa05162 | 1.12905347 |
40 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.12613716 |
41 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.12336616 |
42 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.12180361 |
43 | Hepatitis B_Homo sapiens_hsa05161 | 1.11423819 |
44 | Long-term potentiation_Homo sapiens_hsa04720 | 1.10690635 |
45 | Viral myocarditis_Homo sapiens_hsa05416 | 1.10318381 |
46 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.09413115 |
47 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.08653204 |
48 | Bladder cancer_Homo sapiens_hsa05219 | 1.08337044 |
49 | Melanogenesis_Homo sapiens_hsa04916 | 1.04567099 |
50 | Adherens junction_Homo sapiens_hsa04520 | 1.03305641 |
51 | Endometrial cancer_Homo sapiens_hsa05213 | 1.02466397 |
52 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.02332368 |
53 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.98366035 |
54 | Influenza A_Homo sapiens_hsa05164 | 0.97957137 |
55 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.97247440 |
56 | Prostate cancer_Homo sapiens_hsa05215 | 0.96733343 |
57 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.96178909 |
58 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.95405050 |
59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.95227376 |
60 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.94381464 |
61 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.94105845 |
62 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.90551986 |
63 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.88438737 |
64 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.87808426 |
65 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.87048052 |
66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.86173719 |
67 | Apoptosis_Homo sapiens_hsa04210 | 0.86023621 |
68 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.85726154 |
69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.85429934 |
70 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.83866699 |
71 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.83506828 |
72 | Axon guidance_Homo sapiens_hsa04360 | 0.82397393 |
73 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.82008414 |
74 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.81723643 |
75 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.80709264 |
76 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.80583925 |
77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.79903999 |
78 | Leishmaniasis_Homo sapiens_hsa05140 | 0.79521598 |
79 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.79441766 |
80 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.79240238 |
81 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.79012689 |
82 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.78330033 |
83 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.78178861 |
84 | Glioma_Homo sapiens_hsa05214 | 0.77190417 |
85 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.76939009 |
86 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.76275109 |
87 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.75993949 |
88 | Insulin resistance_Homo sapiens_hsa04931 | 0.75175923 |
89 | Gap junction_Homo sapiens_hsa04540 | 0.75157523 |
90 | Pathways in cancer_Homo sapiens_hsa05200 | 0.74502415 |
91 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.74046781 |
92 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.71493570 |
93 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.70822849 |
94 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.70325940 |
95 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.69857034 |
96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.69557230 |
97 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.68878237 |
98 | Melanoma_Homo sapiens_hsa05218 | 0.68778488 |
99 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.68381500 |
100 | Prion diseases_Homo sapiens_hsa05020 | 0.68188606 |
101 | Platelet activation_Homo sapiens_hsa04611 | 0.67135876 |
102 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.66733293 |
103 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.66562994 |
104 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.66178677 |
105 | Amoebiasis_Homo sapiens_hsa05146 | 0.66046719 |
106 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.65962950 |
107 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.65119646 |
108 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.64435891 |
109 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63805785 |
110 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.63424536 |
111 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.63152140 |
112 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62859044 |
113 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.62771729 |
114 | Tight junction_Homo sapiens_hsa04530 | 0.62392058 |
115 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.61828256 |
116 | Hepatitis C_Homo sapiens_hsa05160 | 0.61642876 |
117 | Focal adhesion_Homo sapiens_hsa04510 | 0.59803724 |
118 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.59327562 |
119 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.59249649 |
120 | Shigellosis_Homo sapiens_hsa05131 | 0.58909115 |
121 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58750224 |
122 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57943530 |
123 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.57832261 |
124 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.57571827 |
125 | Thyroid cancer_Homo sapiens_hsa05216 | 0.57461040 |
126 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.57341536 |
127 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.55979232 |
128 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.55961777 |
129 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.54737892 |
130 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51720323 |
131 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.51523518 |
132 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.50831344 |
133 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50437322 |
134 | Long-term depression_Homo sapiens_hsa04730 | 0.49609777 |