EPC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)5.25472777
2regulation of RNA export from nucleus (GO:0046831)5.16934600
3regulation of nucleobase-containing compound transport (GO:0032239)4.47602847
4cytoplasmic mRNA processing body assembly (GO:0033962)4.33140868
5pre-miRNA processing (GO:0031054)4.09357506
6monoubiquitinated protein deubiquitination (GO:0035520)4.07122098
7positive regulation of gamma-delta T cell activation (GO:0046645)4.05874436
8positive regulation of mitotic sister chromatid separation (GO:1901970)4.03744149
9positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.03744149
10positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.03744149
11nuclear pore complex assembly (GO:0051292)3.88221197
12negative regulation of erythrocyte differentiation (GO:0045647)3.70636726
13nuclear pore organization (GO:0006999)3.64309400
14regulation of sister chromatid cohesion (GO:0007063)3.60328967
15glucocorticoid receptor signaling pathway (GO:0042921)3.57720374
16negative regulation of histone methylation (GO:0031061)3.42341982
17mitotic chromosome condensation (GO:0007076)3.39951696
18corticosteroid receptor signaling pathway (GO:0031958)3.39337037
19stress granule assembly (GO:0034063)3.38004369
20phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.29107632
21positive regulation of chromosome segregation (GO:0051984)3.25349481
22embryonic process involved in female pregnancy (GO:0060136)3.19666408
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.19397444
24positive regulation by organism of defense response of other organism involved in symbiotic interact3.19397444
25modulation by symbiont of host immune response (GO:0052553)3.19397444
26positive regulation by symbiont of host defense response (GO:0052509)3.19397444
27modulation by symbiont of host defense response (GO:0052031)3.19397444
28modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.19397444
29regulation of gamma-delta T cell differentiation (GO:0045586)3.18498492
30regulation of gamma-delta T cell activation (GO:0046643)3.18459283
31histone H2A monoubiquitination (GO:0035518)3.18089936
32gonadal mesoderm development (GO:0007506)3.17167646
33positive T cell selection (GO:0043368)3.14028203
34nerve growth factor signaling pathway (GO:0038180)3.13657315
35cellular response to ethanol (GO:0071361)3.11800288
36regulation of histone H3-K27 methylation (GO:0061085)3.10679556
37sister chromatid segregation (GO:0000819)3.08657780
38regulation of histone H3-K9 methylation (GO:0051570)3.08040480
39regulation of spindle organization (GO:0090224)3.00130559
40positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.99419598
41detection of molecule of bacterial origin (GO:0032490)2.99014722
42response to muramyl dipeptide (GO:0032495)2.98616207
43L-fucose catabolic process (GO:0042355)2.95854034
44fucose catabolic process (GO:0019317)2.95854034
45L-fucose metabolic process (GO:0042354)2.95854034
46cellular extravasation (GO:0045123)2.93413433
47B cell receptor signaling pathway (GO:0050853)2.92788583
48regulation of B cell receptor signaling pathway (GO:0050855)2.88899293
49sister chromatid cohesion (GO:0007062)2.85515517
50histone H3-K4 methylation (GO:0051568)2.84955156
51positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.80625030
52protein localization to kinetochore (GO:0034501)2.80132767
53mRNA splice site selection (GO:0006376)2.79756783
54cerebellar Purkinje cell differentiation (GO:0021702)2.79480787
55regulation of mitotic spindle organization (GO:0060236)2.78462262
56pore complex assembly (GO:0046931)2.75954220
57macrophage activation involved in immune response (GO:0002281)2.75922867
58histone H3-K9 demethylation (GO:0033169)2.75297521
59histone H3-K9 methylation (GO:0051567)2.75282586
60definitive hemopoiesis (GO:0060216)2.73083080
61positive regulation of mRNA processing (GO:0050685)2.71952314
62NLS-bearing protein import into nucleus (GO:0006607)2.71181269
63regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.70395554
64negative T cell selection (GO:0043383)2.67288432
65negative thymic T cell selection (GO:0045060)2.66667218
66histone H4-K16 acetylation (GO:0043984)2.64785993
67protein localization to chromosome, centromeric region (GO:0071459)2.63768915
68protein localization to chromosome (GO:0034502)2.63643310
69histone lysine demethylation (GO:0070076)2.63509380
70peptidyl-threonine phosphorylation (GO:0018107)2.62815282
71regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.62733499
72positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.62733499
73establishment of nucleus localization (GO:0040023)2.61760968
74regulation of DNA endoreduplication (GO:0032875)2.61697977
75positive regulation by host of viral transcription (GO:0043923)2.61126924
76regulation of ARF protein signal transduction (GO:0032012)2.60679450
77positive regulation of RNA splicing (GO:0033120)2.59579613
78mitotic metaphase plate congression (GO:0007080)2.58914180
79histone H3-K4 trimethylation (GO:0080182)2.57185429
80negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.56767600
81negative regulation of translation, ncRNA-mediated (GO:0040033)2.56767600
82regulation of translation, ncRNA-mediated (GO:0045974)2.56767600
83regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.56414159
84positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.56414159
85positive regulation of Rap GTPase activity (GO:0032854)2.55457808
86germinal center formation (GO:0002467)2.55334536
87histone H3-K9 modification (GO:0061647)2.54657711
88histone H3-K36 demethylation (GO:0070544)2.54275273
89alternative mRNA splicing, via spliceosome (GO:0000380)2.51444979
90mitotic sister chromatid segregation (GO:0000070)2.51310076
91positive thymic T cell selection (GO:0045059)2.50475671
92regulation of telomere maintenance (GO:0032204)2.50109722
93embryonic retina morphogenesis in camera-type eye (GO:0060059)2.49734995
94negative regulation of DNA-dependent DNA replication (GO:2000104)2.49368626
95layer formation in cerebral cortex (GO:0021819)2.46998402
96SMAD protein complex assembly (GO:0007183)2.45918622
97T cell selection (GO:0045058)2.45578955
98positive regulation of granulocyte differentiation (GO:0030854)2.45034435
99positive regulation of mRNA metabolic process (GO:1903313)2.44928573
100peptidyl-threonine modification (GO:0018210)2.44524594
101negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.42820114
102negative regulation of cell killing (GO:0031342)2.42820114
103regulation of telomere maintenance via telomerase (GO:0032210)2.41881493
104histone demethylation (GO:0016577)2.41733425
105glucosamine-containing compound catabolic process (GO:1901072)2.40497984
106hippo signaling (GO:0035329)2.40068447
107regulation of Rap GTPase activity (GO:0032317)2.38590661
108nuclear envelope disassembly (GO:0051081)2.38497001
109membrane disassembly (GO:0030397)2.38497001
110metaphase plate congression (GO:0051310)2.38122629
111interkinetic nuclear migration (GO:0022027)2.37758229
112negative regulation of histone modification (GO:0031057)2.37027674
113mitotic nuclear envelope disassembly (GO:0007077)2.36967845
114RNA stabilization (GO:0043489)2.36644409
115mRNA stabilization (GO:0048255)2.36644409
116N-terminal protein amino acid acetylation (GO:0006474)2.36291204
117response to peptidoglycan (GO:0032494)2.35691486
118myeloid leukocyte mediated immunity (GO:0002444)2.35622700
119regulation of interferon-beta biosynthetic process (GO:0045357)2.35457832
120antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.35386873
121peptidyl-lysine trimethylation (GO:0018023)2.35052491
122nucleus localization (GO:0051647)2.34408564
123negative regulation of glial cell proliferation (GO:0060253)2.34300241
124positive regulation of translational initiation (GO:0045948)2.33918915
125histone lysine methylation (GO:0034968)2.33616884
126response to interleukin-15 (GO:0070672)2.33206153
127regulation of clathrin-mediated endocytosis (GO:2000369)2.32942476
128regulation of NFAT protein import into nucleus (GO:0051532)2.32724799
129leukocyte aggregation (GO:0070486)2.32280332
130negative regulation of fibroblast apoptotic process (GO:2000270)2.31559385
131microglial cell activation (GO:0001774)2.31226278
132regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.31009009
133neutrophil mediated immunity (GO:0002446)2.30701061
134regulation of mRNA splicing, via spliceosome (GO:0048024)2.30661024
135positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.30118810
136response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.29019569
137response to host immune response (GO:0052572)2.29019569
138dosage compensation (GO:0007549)2.28802889
139response to nerve growth factor (GO:1990089)2.28328617
140cellular response to nerve growth factor stimulus (GO:1990090)2.28328617
141negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.28238519
142DNA duplex unwinding (GO:0032508)2.27897324
143positive regulation of DNA-templated transcription, initiation (GO:2000144)2.27792003
144positive regulation of histone H3-K4 methylation (GO:0051571)2.26878940
145regulation of mRNA processing (GO:0050684)2.26712331
146DNA geometric change (GO:0032392)2.26508671
147regulation of mRNA 3-end processing (GO:0031440)2.25761048
148regulation of cAMP-dependent protein kinase activity (GO:2000479)2.25607190
149antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.25536684
150response to laminar fluid shear stress (GO:0034616)2.25467017
151T cell migration (GO:0072678)2.25106271
152protein dealkylation (GO:0008214)2.24352376
153protein demethylation (GO:0006482)2.24352376
154positive regulation of mRNA 3-end processing (GO:0031442)2.24105790
155mitotic cytokinesis (GO:0000281)2.23018438
156response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.22892690
157response to host (GO:0075136)2.22892690
158response to host defenses (GO:0052200)2.22892690
159regulation of granulocyte differentiation (GO:0030852)2.22633976
160regulation of interleukin-12 biosynthetic process (GO:0045075)2.21740380
161DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.21675143
162microtubule depolymerization (GO:0007019)2.21397449
163embryonic camera-type eye morphogenesis (GO:0048596)2.20065261
164regulation of histone methylation (GO:0031060)2.19284490
165centrosome localization (GO:0051642)2.19002963
166antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.18795457
167Rap protein signal transduction (GO:0032486)2.18068651
168negative regulation of myotube differentiation (GO:0010832)2.16240741
169negative regulation of T cell mediated immunity (GO:0002710)2.15811975
170B cell homeostasis (GO:0001782)2.15475785
171macrophage activation (GO:0042116)2.15390876
172negative regulation of lymphocyte mediated immunity (GO:0002707)2.14593180
173regulation of necroptotic process (GO:0060544)2.13794641
174thymic T cell selection (GO:0045061)2.13200477

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.96287351
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.98740644
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.29395039
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.61972240
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.28931924
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.76572293
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.74041637
8KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.73763681
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.58379013
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53287944
11VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.48560561
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.46336731
13TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.40333509
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.26150578
15EZH2_22144423_ChIP-Seq_EOC_Human2.22253730
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.21936219
17RUNX_20019798_ChIP-Seq_JUKART_Human2.18226961
18SCL_19346495_ChIP-Seq_HPC-7_Human2.10265579
19GATA1_22025678_ChIP-Seq_K562_Human2.06779280
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.04504021
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.04402501
22SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.85030113
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.84973879
24FUS_26573619_Chip-Seq_HEK293_Human1.79558418
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.77897703
26MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.74934216
27* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.73108324
28PKCTHETA_26484144_Chip-Seq_BREAST_Human1.73047714
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.72889070
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.71851166
31IRF8_27001747_Chip-Seq_BMDM_Mouse1.70666911
32TP53_16413492_ChIP-PET_HCT116_Human1.69810865
33VDR_24787735_ChIP-Seq_THP-1_Human1.66573856
34EWS_26573619_Chip-Seq_HEK293_Human1.66135957
35Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.64066769
36KDM2B_26808549_Chip-Seq_SUP-B15_Human1.62828844
37FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.58735524
38KDM2B_26808549_Chip-Seq_DND41_Human1.55659646
39ZNF217_24962896_ChIP-Seq_MCF-7_Human1.55146209
40DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.52167758
41RBPJ_22232070_ChIP-Seq_NCS_Mouse1.50195886
42ZNF274_21170338_ChIP-Seq_K562_Hela1.48594261
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.48579298
44STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.48518254
45GBX2_23144817_ChIP-Seq_PC3_Human1.47313908
46MYB_26560356_Chip-Seq_TH2_Human1.46238666
47KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.45505745
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43881063
49KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.43003360
50KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.43003360
51KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.43003360
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.40644494
53HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.39285200
54BRD4_27068464_Chip-Seq_AML-cells_Mouse1.36792384
55VDR_24763502_ChIP-Seq_THP-1_Human1.35970123
56AR_21572438_ChIP-Seq_LNCaP_Human1.35092252
57SPI1_23127762_ChIP-Seq_K562_Human1.34960626
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.33439861
59WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.33359169
60IRF8_22096565_ChIP-ChIP_GC-B_Human1.32980162
61TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.32482472
62ZFP281_27345836_Chip-Seq_ESCs_Mouse1.32175085
63MYB_26560356_Chip-Seq_TH1_Human1.32074886
64IGF1R_20145208_ChIP-Seq_DFB_Human1.32068657
65PU_27001747_Chip-Seq_BMDM_Mouse1.31177354
66TCF4_18268006_ChIP-ChIP_LS174T_Human1.29925336
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29740208
68FOXO3_23340844_ChIP-Seq_DLD1_Human1.28108904
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.26192125
70PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.25471017
71* KDM2B_26808549_Chip-Seq_K562_Human1.24225816
72FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.20832028
73TBX3_20139965_ChIP-Seq_ESCs_Mouse1.20431803
74STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.19945222
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.19792788
76KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.18733823
77TBX3_20139965_ChIP-Seq_MESCs_Mouse1.18078313
78CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17255876
79ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.16578078
80* STAT3_23295773_ChIP-Seq_U87_Human1.15615151
81YAP1_20516196_ChIP-Seq_MESCs_Mouse1.15226218
82* SMAD4_21799915_ChIP-Seq_A2780_Human1.14000820
83CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13746681
84ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.13246627
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.12637778
86VDR_21846776_ChIP-Seq_THP-1_Human1.12563770
87* BRD4_25478319_ChIP-Seq_HGPS_Human1.12293523
88* MAF_26560356_Chip-Seq_TH1_Human1.12058262
89* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11630296
90NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09488706
91GATA1_19941826_ChIP-Seq_K562_Human1.09419975
92MYC_22102868_ChIP-Seq_BL_Human1.09281431
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08761060
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08761060
95AHR_22903824_ChIP-Seq_MCF-7_Human1.08356897
96TCF4_23295773_ChIP-Seq_U87_Human1.07682044
97GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06751143
98SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06199008
99* P300_19829295_ChIP-Seq_ESCs_Human1.04667467
100IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.03515155
101ARNT_22903824_ChIP-Seq_MCF-7_Human1.03240883
102EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03027613
103* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.00387080
104TCF7_22412390_ChIP-Seq_EML_Mouse0.99737447
105GATA3_27048872_Chip-Seq_THYMUS_Human0.98901924
106KDM2B_26808549_Chip-Seq_JURKAT_Human0.98506280
107* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98230013
108WT1_19549856_ChIP-ChIP_CCG9911_Human0.97899976
109* ISL1_27105846_Chip-Seq_CPCs_Mouse0.97601345
110RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.97027940
111CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97022181
112GATA2_19941826_ChIP-Seq_K562_Human0.96741357
113NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94495614
114GF1_26923725_Chip-Seq_HPCs_Mouse0.94416122
115PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94034473
116GATA1_19941827_ChIP-Seq_MEL_Mouse0.93949105
117PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93110907
118PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92827881
119ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.92533237
120AR_19668381_ChIP-Seq_PC3_Human0.92358594
121SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.91905577
122GATA1_19941827_ChIP-Seq_MEL86_Mouse0.91545566
123PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90929644
124RARB_27405468_Chip-Seq_BRAIN_Mouse0.90763638
125SMAD3_21741376_ChIP-Seq_EPCs_Human0.90477361
126* FOXA2_19822575_ChIP-Seq_HepG2_Human0.90364173
127* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90076348
128FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89797703
129AR_21909140_ChIP-Seq_LNCAP_Human0.89620428
130* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.89349067
131UTX_26944678_Chip-Seq_JUKART_Human0.89190455
132RING1B_27294783_Chip-Seq_NPCs_Mouse0.88961318
133STAT6_21828071_ChIP-Seq_BEAS2B_Human0.88260249
134WT1_25993318_ChIP-Seq_PODOCYTE_Human0.87846755
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.87425379
136RUNX1_22412390_ChIP-Seq_EML_Mouse0.86093583
137NR3C1_23031785_ChIP-Seq_PC12_Mouse0.85819745
138GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85569165
139NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85420438
140CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84670167
141P53_22127205_ChIP-Seq_FIBROBLAST_Human0.83790725
142* NANOG_18555785_Chip-Seq_ESCs_Mouse0.83562587
143TAF15_26573619_Chip-Seq_HEK293_Human0.83432231
144CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.82646490
145STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.81926771
146YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.81379620
147RNF2_27304074_Chip-Seq_NSC_Mouse0.80961129
148TOP2B_26459242_ChIP-Seq_MCF-7_Human0.80678328
149* SOX2_21211035_ChIP-Seq_LN229_Gbm0.79915838
150ZFP57_27257070_Chip-Seq_ESCs_Mouse0.79535481
151RNF2_27304074_Chip-Seq_ESCs_Mouse0.79138825
152CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.79070278
153MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.78557684

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.74219875
2MP0003787_abnormal_imprinting3.54037680
3MP0008057_abnormal_DNA_replication3.22261037
4MP0005076_abnormal_cell_differentiation3.13461363
5MP0003763_abnormal_thymus_physiology2.64514001
6MP0003890_abnormal_embryonic-extraembry2.53097245
7MP0003121_genomic_imprinting2.45198887
8MP0003111_abnormal_nucleus_morphology2.39296447
9MP0003436_decreased_susceptibility_to2.32483458
10MP0005409_darkened_coat_color2.29540565
11MP0008877_abnormal_DNA_methylation2.29060254
12MP0002877_abnormal_melanocyte_morpholog2.27896558
13MP0010307_abnormal_tumor_latency2.14836512
14MP0003724_increased_susceptibility_to2.11539436
15MP0002009_preneoplasia2.09405407
16MP0010094_abnormal_chromosome_stability1.99464361
17MP0002166_altered_tumor_susceptibility1.95327932
18MP0003077_abnormal_cell_cycle1.84739710
19MP0001800_abnormal_humoral_immune1.83106157
20MP0005397_hematopoietic_system_phenotyp1.74676207
21MP0001545_abnormal_hematopoietic_system1.74676207
22MP0003656_abnormal_erythrocyte_physiolo1.74343909
23MP0010352_gastrointestinal_tract_polyps1.72364367
24MP0001348_abnormal_lacrimal_gland1.71592482
25MP0001835_abnormal_antigen_presentation1.70591205
26MP0001851_eye_inflammation1.70104401
27MP0003172_abnormal_lysosome_physiology1.67306939
28MP0004947_skin_inflammation1.66219868
29MP0009780_abnormal_chondrocyte_physiolo1.64990907
30MP0003705_abnormal_hypodermis_morpholog1.61605365
31MP0002398_abnormal_bone_marrow1.60492513
32MP0002084_abnormal_developmental_patter1.58897343
33MP0006054_spinal_hemorrhage1.57816029
34MP0003303_peritoneal_inflammation1.54556555
35MP0003690_abnormal_glial_cell1.50742955
36MP0004808_abnormal_hematopoietic_stem1.49282373
37MP0005451_abnormal_body_composition1.45737291
38MP0004130_abnormal_muscle_cell1.45285613
39MP0001188_hyperpigmentation1.44743172
40MP0004859_abnormal_synaptic_plasticity1.42710289
41MP0000350_abnormal_cell_proliferation1.42060125
42MP0003755_abnormal_palate_morphology1.41035946
43MP0002419_abnormal_innate_immunity1.40459150
44MP0002420_abnormal_adaptive_immunity1.39329697
45MP0003935_abnormal_craniofacial_develop1.39128418
46MP0002086_abnormal_extraembryonic_tissu1.39090242
47MP0008007_abnormal_cellular_replicative1.38770923
48MP0005380_embryogenesis_phenotype1.38003875
49MP0001672_abnormal_embryogenesis/_devel1.38003875
50MP0000428_abnormal_craniofacial_morphol1.34848700
51MP0009703_decreased_birth_body1.34594134
52MP0003300_gastrointestinal_ulcer1.34101389
53MP0003984_embryonic_growth_retardation1.34030695
54MP0001819_abnormal_immune_cell1.33181070
55MP0004381_abnormal_hair_follicle1.32124242
56MP0005000_abnormal_immune_tolerance1.31940412
57MP0002085_abnormal_embryonic_tissue1.31644812
58MP0002088_abnormal_embryonic_growth/wei1.31070111
59MP0004185_abnormal_adipocyte_glucose1.30941406
60MP0003122_maternal_imprinting1.30871184
61MP0002723_abnormal_immune_serum1.29861283
62MP0002452_abnormal_antigen_presenting1.29803919
63MP0008260_abnormal_autophagy1.26450889
64MP0003123_paternal_imprinting1.26350651
65MP0000716_abnormal_immune_system1.25970342
66MP0004197_abnormal_fetal_growth/weight/1.25783996
67MP0005187_abnormal_penis_morphology1.25442940
68MP0003385_abnormal_body_wall1.25143125
69MP0000778_abnormal_nervous_system1.24467287
70MP0001730_embryonic_growth_arrest1.24364608
71MP0002822_catalepsy1.23915943
72MP0003937_abnormal_limbs/digits/tail_de1.23145294
73MP0001697_abnormal_embryo_size1.22343508
74MP0000733_abnormal_muscle_development1.20197720
75MP0003221_abnormal_cardiomyocyte_apopto1.20032780
76MP0003861_abnormal_nervous_system1.19827802
77MP0002405_respiratory_system_inflammati1.18904820
78MP0002925_abnormal_cardiovascular_devel1.18868498
79MP0000432_abnormal_head_morphology1.18310461
80MP0002722_abnormal_immune_system1.18029904
81MP0003693_abnormal_embryo_hatching1.16648454
82MP0002396_abnormal_hematopoietic_system1.14439855
83MP0003045_fibrosis1.12175328
84MP0004264_abnormal_extraembryonic_tissu1.10616060
85MP0003119_abnormal_digestive_system1.10477388
86MP0005394_taste/olfaction_phenotype1.10362087
87MP0005499_abnormal_olfactory_system1.10362087
88MP0000516_abnormal_urinary_system1.08544139
89MP0005367_renal/urinary_system_phenotyp1.08544139
90MP0001915_intracranial_hemorrhage1.07777849
91MP0000015_abnormal_ear_pigmentation1.07383922
92MP0004957_abnormal_blastocyst_morpholog1.04359848
93MP0002116_abnormal_craniofacial_bone1.04272149
94MP0002998_abnormal_bone_remodeling1.04253321
95MP0003567_abnormal_fetal_cardiomyocyte1.01826238
96MP0003941_abnormal_skin_development1.01792173
97MP0000689_abnormal_spleen_morphology1.00644195
98MP0005025_abnormal_response_to1.00370322
99MP0004883_abnormal_blood_vessel1.00040135
100MP0001790_abnormal_immune_system0.98689290
101MP0005387_immune_system_phenotype0.98689290
102MP0006292_abnormal_olfactory_placode0.98496886
103MP0003453_abnormal_keratinocyte_physiol0.98281617
104MP0003115_abnormal_respiratory_system0.96714309
105MP0003635_abnormal_synaptic_transmissio0.95762414
106MP0003828_pulmonary_edema0.95343191
107MP0002177_abnormal_outer_ear0.95271567
108MP0004885_abnormal_endolymph0.95019592
109MP0005174_abnormal_tail_pigmentation0.94458528
110MP0008789_abnormal_olfactory_epithelium0.93182179
111MP0005310_abnormal_salivary_gland0.92876722
112MP0002233_abnormal_nose_morphology0.91312678
113MP0002429_abnormal_blood_cell0.90879531
114MP0005621_abnormal_cell_physiology0.90605240
115MP0005623_abnormal_meninges_morphology0.90328072
116MP0009053_abnormal_anal_canal0.87982126
117MP0002006_tumorigenesis0.87714505
118MP0006072_abnormal_retinal_apoptosis0.87363912
119MP0002081_perinatal_lethality0.85117033
120MP0002933_joint_inflammation0.85115126
121MP0003091_abnormal_cell_migration0.84711161
122MP0002133_abnormal_respiratory_system0.84341747
123MP0005388_respiratory_system_phenotype0.84341747
124MP0003866_abnormal_defecation0.84204839
125MP0009278_abnormal_bone_marrow0.84111086
126MP0002092_abnormal_eye_morphology0.82672938
127MP0004858_abnormal_nervous_system0.81815650
128MP0002063_abnormal_learning/memory/cond0.81615264
129MP0002152_abnormal_brain_morphology0.81516519
130MP0001853_heart_inflammation0.80998118
131MP0000703_abnormal_thymus_morphology0.80893079
132MP0010630_abnormal_cardiac_muscle0.80398785
133MP0009115_abnormal_fat_cell0.80253165
134MP0003183_abnormal_peptide_metabolism0.80161733
135MP0008058_abnormal_DNA_repair0.80011072
136MP0005248_abnormal_Harderian_gland0.78938679
137MP0005671_abnormal_response_to0.78469460
138MP0002080_prenatal_lethality0.78412592
139MP0003283_abnormal_digestive_organ0.77973947
140MP0001849_ear_inflammation0.77671741
141MP0003943_abnormal_hepatobiliary_system0.76893042
142MP0002114_abnormal_axial_skeleton0.76027342
143MP0009672_abnormal_birth_weight0.75267330
144MP0001299_abnormal_eye_distance/0.74872432
145MP0001533_abnormal_skeleton_physiology0.74871042
146MP0004484_altered_response_of0.74795267
147MP0003880_abnormal_central_pattern0.73963981
148MP0005666_abnormal_adipose_tissue0.72956127
149MP0010234_abnormal_vibrissa_follicle0.72738024
150MP0000685_abnormal_immune_system0.72132121
151MP0000383_abnormal_hair_follicle0.72118139
152MP0001784_abnormal_fluid_regulation0.71839395
153MP0009250_abnormal_appendicular_skeleto0.71684989
154MP0010678_abnormal_skin_adnexa0.70484751
155MP0002102_abnormal_ear_morphology0.69345686
156MP0005464_abnormal_platelet_physiology0.68648994
157MP0001943_abnormal_respiration0.68401283
158MP0000631_abnormal_neuroendocrine_gland0.67948917
159MP0002234_abnormal_pharynx_morphology0.67636306
160MP0000266_abnormal_heart_morphology0.67484952
161MP0003868_abnormal_feces_composition0.64001557
162MP0001879_abnormal_lymphatic_vessel0.63172817
163MP0010155_abnormal_intestine_physiology0.61001974

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.41698355
2Volvulus (HP:0002580)4.37705064
3Papillary thyroid carcinoma (HP:0002895)3.49260911
4Spontaneous hematomas (HP:0007420)3.42561504
5Facial hemangioma (HP:0000329)3.16725882
6Eczematoid dermatitis (HP:0000976)2.97898322
7T lymphocytopenia (HP:0005403)2.91882796
8Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.80685412
9Narrow palate (HP:0000189)2.67977217
10Abnormality of the nasal septum (HP:0000419)2.66993054
11Macroorchidism (HP:0000053)2.60862784
12Recurrent bacterial skin infections (HP:0005406)2.59212642
13Oligodontia (HP:0000677)2.51742152
14Heterotopia (HP:0002282)2.48188490
15Abnormality of T cell number (HP:0011839)2.45078279
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.41420716
17Short 4th metacarpal (HP:0010044)2.41420716
18Subaortic stenosis (HP:0001682)2.40949798
19Abnormality of the left ventricular outflow tract (HP:0011103)2.40949798
20Long eyelashes (HP:0000527)2.39564155
21Truncal obesity (HP:0001956)2.39120287
22Deep palmar crease (HP:0006191)2.37374692
23Shallow orbits (HP:0000586)2.30809096
24Medulloblastoma (HP:0002885)2.24400028
25Obstructive sleep apnea (HP:0002870)2.22728513
26Genetic anticipation (HP:0003743)2.21525909
27Transitional cell carcinoma of the bladder (HP:0006740)2.21005832
28Overgrowth (HP:0001548)2.20464577
29Dislocated radial head (HP:0003083)2.18049942
30Recurrent abscess formation (HP:0002722)2.17013223
31Sparse lateral eyebrow (HP:0005338)2.16882946
32Dysmetric saccades (HP:0000641)2.15289323
33Subacute progressive viral hepatitis (HP:0006572)2.14414553
34Absent frontal sinuses (HP:0002688)2.11175427
35Abnormality of the labia minora (HP:0012880)2.05375324
36Hypochromic microcytic anemia (HP:0004840)2.05216642
37Abnormality of the radial head (HP:0003995)2.05030248
38Curly hair (HP:0002212)2.04977690
39Increased nuchal translucency (HP:0010880)2.02757329
40Hypoplasia of the maxilla (HP:0000327)2.02281620
41Gingivitis (HP:0000230)2.00705332
42Lip pit (HP:0100267)1.99564862
43Thyroid carcinoma (HP:0002890)1.98734046
44Cubitus valgus (HP:0002967)1.98153978
45Bladder neoplasm (HP:0009725)1.97880331
46Bladder carcinoma (HP:0002862)1.97880331
47Broad thumb (HP:0011304)1.97849939
48Neonatal hypoglycemia (HP:0001998)1.97708831
49Recurrent viral infections (HP:0004429)1.97241853
50Drooling (HP:0002307)1.95821571
51Excessive salivation (HP:0003781)1.95821571
52Gastrointestinal carcinoma (HP:0002672)1.95148444
53Malignant gastrointestinal tract tumors (HP:0006749)1.95148444
54Trigonocephaly (HP:0000243)1.94519155
55Arterial tortuosity (HP:0005116)1.93026619
56Cystic hygroma (HP:0000476)1.91498510
57Recurrent gram-negative bacterial infections (HP:0005420)1.91373385
58Impaired smooth pursuit (HP:0007772)1.90253259
59Germ cell neoplasia (HP:0100728)1.88067347
60Obsessive-compulsive behavior (HP:0000722)1.87859033
61Aqueductal stenosis (HP:0002410)1.87667106
62Abnormality of chromosome segregation (HP:0002916)1.87383962
63Broad ribs (HP:0000885)1.85812333
64Cellulitis (HP:0100658)1.84622353
65Capillary hemangiomas (HP:0005306)1.83867530
66Neoplasm of the small intestine (HP:0100833)1.83213579
67Oligodactyly (hands) (HP:0001180)1.82598056
68Colitis (HP:0002583)1.82558494
69Slow saccadic eye movements (HP:0000514)1.82059800
70Thickened calvaria (HP:0002684)1.81568002
71Shawl scrotum (HP:0000049)1.81192149
72Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81069472
73Astrocytoma (HP:0009592)1.80731957
74Abnormality of the astrocytes (HP:0100707)1.80731957
75Impulsivity (HP:0100710)1.80428820
76Widely spaced teeth (HP:0000687)1.79451553
77Prominent nose (HP:0000448)1.79140732
78Recurrent fungal infections (HP:0002841)1.77983640
79Inappropriate behavior (HP:0000719)1.77728197
80Thin upper lip vermilion (HP:0000219)1.77634134
81Abnormal hair whorl (HP:0010721)1.77545053
82Difficulty running (HP:0009046)1.77385969
83Febrile seizures (HP:0002373)1.76970630
84Vertebral arch anomaly (HP:0008438)1.76747482
85Low anterior hairline (HP:0000294)1.76548799
86Abnormality of the columella (HP:0009929)1.76022070
87Abnormality of incisor morphology (HP:0011063)1.75890489
88Uterine leiomyosarcoma (HP:0002891)1.74950568
89Leiomyosarcoma (HP:0100243)1.74950568
90Deep philtrum (HP:0002002)1.74915517
91Menstrual irregularities (HP:0000858)1.72998798
92Supernumerary ribs (HP:0005815)1.72836583
93Midline defect of the nose (HP:0004122)1.72194662
94Sacral dimple (HP:0000960)1.71302571
95Coarse hair (HP:0002208)1.70594612
96Pelvic girdle muscle weakness (HP:0003749)1.70512810
97Biliary tract neoplasm (HP:0100574)1.69630379
98Mediastinal lymphadenopathy (HP:0100721)1.69242144
99Acute lymphatic leukemia (HP:0006721)1.68881991
100Termporal pattern (HP:0011008)1.67757307
101Insidious onset (HP:0003587)1.67757307
102Sporadic (HP:0003745)1.66125306
103Cortical dysplasia (HP:0002539)1.65834417
104Abnormality of the distal phalanx of the thumb (HP:0009617)1.65683771
105Panhypogammaglobulinemia (HP:0003139)1.65497373
106Broad phalanges of the hand (HP:0009768)1.64496565
107Mask-like facies (HP:0000298)1.63483311
108Viral hepatitis (HP:0006562)1.63144106
109Chromsome breakage (HP:0040012)1.62561454
110Large earlobe (HP:0009748)1.62547587
111Neoplasm of the tracheobronchial system (HP:0100552)1.61161401
112Abnormality of ocular smooth pursuit (HP:0000617)1.60831373
113Abnormality of the 4th metacarpal (HP:0010012)1.60586343
114Asymmetry of the thorax (HP:0001555)1.60557756
115Dental malocclusion (HP:0000689)1.60173218
116Relative macrocephaly (HP:0004482)1.59891512
117Thick eyebrow (HP:0000574)1.59481135
118Acute myeloid leukemia (HP:0004808)1.59208312
119Peripheral hypomyelination (HP:0007182)1.59119144
120Somatic mutation (HP:0001428)1.59007157
121Hepatoblastoma (HP:0002884)1.59004333
122Recurrent skin infections (HP:0001581)1.58801752
123Gastrointestinal infarctions (HP:0005244)1.58731457
124Neoplasm of the adrenal cortex (HP:0100641)1.58585018
125Abnormality of the peritoneum (HP:0002585)1.58402351
126Rhabdomyosarcoma (HP:0002859)1.58294902
127Vascular tortuosity (HP:0004948)1.58052364
128Cutis marmorata (HP:0000965)1.57746690
129Segmental peripheral demyelination/remyelination (HP:0003481)1.57469642
130Lower limb asymmetry (HP:0100559)1.57305193
131Uterine neoplasm (HP:0010784)1.57218619
132Genu recurvatum (HP:0002816)1.57154569
133Hypoplastic labia majora (HP:0000059)1.56574036
134Shoulder girdle muscle weakness (HP:0003547)1.56287489
135Increased number of teeth (HP:0011069)1.55322093
136Broad finger (HP:0001500)1.54786496
137Papilledema (HP:0001085)1.53575028
138Syringomyelia (HP:0003396)1.53216901
139Spinal cord lesions (HP:0100561)1.53216901
140Aplasia/Hypoplasia of the sternum (HP:0006714)1.52965316
141Abnormality of the right ventricle (HP:0001707)1.52720732
142Neoplasm of the rectum (HP:0100743)1.52519284
143Peritonitis (HP:0002586)1.51966221
144Chromosomal breakage induced by crosslinking agents (HP:0003221)1.51355390
145Mitral valve prolapse (HP:0001634)1.51290212
146Lymphedema (HP:0001004)1.50563659
147Recurrent cutaneous fungal infections (HP:0011370)1.50327381
148Chronic mucocutaneous candidiasis (HP:0002728)1.50327381
149Diastasis recti (HP:0001540)1.50297374
150Renal cell carcinoma (HP:0005584)1.49732994
151Broad phalanx (HP:0006009)1.49382220
152Abnormal delayed hypersensitivity skin test (HP:0002963)1.49153855
153Basal cell carcinoma (HP:0002671)1.49129162
154Sandal gap (HP:0001852)1.48908286
155Spondylolisthesis (HP:0003302)1.48221058
156Glioma (HP:0009733)1.48124346
157Smooth philtrum (HP:0000319)1.47654453
158Broad palm (HP:0001169)1.47461046
159Focal motor seizures (HP:0011153)1.47278719
160Focal seizures (HP:0007359)1.47118011

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K103.19496063
2LATS13.07913478
3PRPF4B3.07769332
4CDK122.88611379
5CDC72.68997795
6STK102.59278387
7MAP3K62.55043799
8STK32.08774786
9MAP3K42.05123394
10PDGFRA2.03266478
11SIK21.98841955
12WNK11.82962526
13MELK1.71592066
14KSR21.70503010
15RIPK11.62919943
16NEK21.62791241
17ACVR1B1.62619688
18EEF2K1.60321844
19CDK91.59396602
20MAP3K91.56614203
21LATS21.56320926
22MARK21.54740945
23BRSK21.53917411
24MAP3K51.53561638
25SGK21.52358032
26FRK1.52259677
27MARK11.51623307
28BRD41.48458821
29CAMKK21.48378315
30PDGFRB1.47047074
31MAP3K131.46998677
32MAP3K141.45378091
33SGK31.43785188
34NLK1.40452696
35DMPK1.39704062
36ICK1.33978235
37CSK1.33761638
38DYRK31.33524761
39CAMKK11.33364830
40BLK1.30269073
41SRPK11.29029386
42CDK61.28642762
43FGFR31.28470307
44FGFR41.22135462
45MAP4K11.21623533
46BTK1.21537361
47NTRK31.20761017
48MAP3K21.18097521
49PLK21.18020862
50EPHA41.17163978
51IRAK41.16934344
52IKBKE1.11889767
53CDK31.11172672
54JAK11.10616044
55CASK1.08863570
56MKNK21.07676197
57IRAK11.07355707
58HIPK21.05683539
59TYK21.05591847
60NUAK11.05160221
61JAK21.03611688
62MAP2K41.01741678
63RIPK41.01427489
64ERBB31.01358862
65NTRK20.99772553
66PLK30.94930605
67FES0.93666149
68NEK90.93194924
69IRAK20.93027313
70MAP2K30.90616202
71ATR0.88095175
72CHEK20.88004361
73TEC0.87621013
74AKT30.86634990
75RET0.86257289
76CAMK1G0.86012852
77MAP3K10.85964873
78MAPK130.85557253
79TYRO30.84431478
80WEE10.82625696
81TXK0.81836194
82DYRK1B0.81367189
83FGFR20.80745556
84ALK0.80598924
85BMPR20.80443128
86ATM0.77839829
87HCK0.77237192
88PNCK0.77002843
89BRSK10.76591699
90CDK20.76468494
91PIM10.76225709
92ZAP700.75497144
93MAPK120.75352461
94RPS6KA40.74564100
95MTOR0.73599258
96CAMK40.71869383
97ITK0.70623070
98EPHA30.70262818
99JAK30.70173457
100MAP3K70.69901609
101TRPM70.69675666
102MARK30.67650516
103FGR0.67239638
104CDK40.67021233
105CDC42BPA0.66667011
106MAPK100.66054069
107ZAK0.65513346
108NEK60.65428269
109CHEK10.65374246
110PRKD20.65052272
111SYK0.65002100
112SGK10.64841833
113AURKB0.64359076
114MKNK10.64090107
115CAMK1D0.63509137
116KSR10.62304997
117MAP3K80.62144465
118CDK10.61120391
119MINK10.60518496
120MAPK140.60496181
121LRRK20.59829119
122SGK4940.59755874
123SGK2230.59755874
124PKN20.58980972
125MAPK70.58818171
126PIK3CA0.58026099
127PDK10.56274428
128MAP2K70.56189922
129SIK10.55668969
130GSK3A0.52787480
131CAMK10.51520497
132CDK80.50776461
133TRIB30.50635536
134TTK0.50432968
135LCK0.49982540
136GSK3B0.48486566
137DYRK1A0.47563646
138PIK3CG0.47435105
139STK380.47384944
140RPS6KB10.45812991
141PTK60.44010238
142ERBB20.43072973
143CSNK1D0.42908471
144STK110.42486126
145TAOK30.42307633
146CSNK1E0.41310464
147PLK10.41255275
148YES10.40684662
149PRKCH0.40602321
150CHUK0.40100743
151TTN0.39904344
152AKT10.39685131
153STK240.38888777
154NTRK10.38072186
155RPS6KB20.37439614
156FLT30.37331460
157RAF10.37002471

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041101.63419757
2Long-term potentiation_Homo sapiens_hsa047201.59470216
3Colorectal cancer_Homo sapiens_hsa052101.51847720
4MicroRNAs in cancer_Homo sapiens_hsa052061.49935079
5Toll-like receptor signaling pathway_Homo sapiens_hsa046201.47290905
6mRNA surveillance pathway_Homo sapiens_hsa030151.39110456
7TGF-beta signaling pathway_Homo sapiens_hsa043501.38948197
8Adherens junction_Homo sapiens_hsa045201.35350903
9Chronic myeloid leukemia_Homo sapiens_hsa052201.32038132
10Glioma_Homo sapiens_hsa052141.30582125
11Oocyte meiosis_Homo sapiens_hsa041141.30414496
12mTOR signaling pathway_Homo sapiens_hsa041501.30118098
13GnRH signaling pathway_Homo sapiens_hsa049121.29870940
14Leishmaniasis_Homo sapiens_hsa051401.28816660
15NOD-like receptor signaling pathway_Homo sapiens_hsa046211.28804187
16Thyroid cancer_Homo sapiens_hsa052161.25652256
17Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.25242667
18Endometrial cancer_Homo sapiens_hsa052131.24659952
19Thyroid hormone signaling pathway_Homo sapiens_hsa049191.23318554
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.23003221
21Neurotrophin signaling pathway_Homo sapiens_hsa047221.22394560
22Estrogen signaling pathway_Homo sapiens_hsa049151.21053483
23FoxO signaling pathway_Homo sapiens_hsa040681.20062084
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18169565
25Phospholipase D signaling pathway_Homo sapiens_hsa040721.16596352
26Pancreatic cancer_Homo sapiens_hsa052121.14807222
27Measles_Homo sapiens_hsa051621.12712461
28Prostate cancer_Homo sapiens_hsa052151.11691501
29Amphetamine addiction_Homo sapiens_hsa050311.11599198
30Nicotine addiction_Homo sapiens_hsa050331.10776758
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.10586508
32NF-kappa B signaling pathway_Homo sapiens_hsa040641.09423195
33Inositol phosphate metabolism_Homo sapiens_hsa005621.09271025
34ErbB signaling pathway_Homo sapiens_hsa040121.08894504
35MAPK signaling pathway_Homo sapiens_hsa040101.08637369
36Renal cell carcinoma_Homo sapiens_hsa052111.08279111
37Non-small cell lung cancer_Homo sapiens_hsa052231.07803451
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07203381
39Dorso-ventral axis formation_Homo sapiens_hsa043201.06961414
40Jak-STAT signaling pathway_Homo sapiens_hsa046301.04934960
41Wnt signaling pathway_Homo sapiens_hsa043101.04925439
42Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.03804632
43TNF signaling pathway_Homo sapiens_hsa046681.03788781
44Long-term depression_Homo sapiens_hsa047301.03565388
45Dopaminergic synapse_Homo sapiens_hsa047281.03495666
46Choline metabolism in cancer_Homo sapiens_hsa052311.03266896
47Transcriptional misregulation in cancer_Homo sapiens_hsa052021.01188319
48Hippo signaling pathway_Homo sapiens_hsa043901.00355945
49RNA transport_Homo sapiens_hsa030130.99716152
50Tuberculosis_Homo sapiens_hsa051520.99624697
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.98618405
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98525994
53Renin secretion_Homo sapiens_hsa049240.98445331
54Influenza A_Homo sapiens_hsa051640.97784015
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.97035667
56Aldosterone synthesis and secretion_Homo sapiens_hsa049250.97022929
57Small cell lung cancer_Homo sapiens_hsa052220.95855932
58Type II diabetes mellitus_Homo sapiens_hsa049300.95521997
59Prolactin signaling pathway_Homo sapiens_hsa049170.94789635
60B cell receptor signaling pathway_Homo sapiens_hsa046620.93912185
61Oxytocin signaling pathway_Homo sapiens_hsa049210.93885467
62VEGF signaling pathway_Homo sapiens_hsa043700.93718114
63Hepatitis B_Homo sapiens_hsa051610.93692806
64RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.93481093
65Proteoglycans in cancer_Homo sapiens_hsa052050.93340237
66Viral carcinogenesis_Homo sapiens_hsa052030.92713322
67Circadian entrainment_Homo sapiens_hsa047130.92514699
68Hepatitis C_Homo sapiens_hsa051600.91696490
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.91164191
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91130501
71Cholinergic synapse_Homo sapiens_hsa047250.89093746
72T cell receptor signaling pathway_Homo sapiens_hsa046600.88536758
73Osteoclast differentiation_Homo sapiens_hsa043800.88162937
74Circadian rhythm_Homo sapiens_hsa047100.88116123
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.86876000
76Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.86723883
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86095750
78Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85770378
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.85598628
80Glutamatergic synapse_Homo sapiens_hsa047240.85220572
81Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.84352767
82Melanogenesis_Homo sapiens_hsa049160.84234599
83p53 signaling pathway_Homo sapiens_hsa041150.82841615
84Olfactory transduction_Homo sapiens_hsa047400.82062865
85Gap junction_Homo sapiens_hsa045400.81819197
86HTLV-I infection_Homo sapiens_hsa051660.81679096
87Fanconi anemia pathway_Homo sapiens_hsa034600.81382327
88Insulin signaling pathway_Homo sapiens_hsa049100.80794255
89cAMP signaling pathway_Homo sapiens_hsa040240.80773970
90RNA degradation_Homo sapiens_hsa030180.80293719
91Leukocyte transendothelial migration_Homo sapiens_hsa046700.79701862
92Axon guidance_Homo sapiens_hsa043600.78945613
93Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.78630993
94Spliceosome_Homo sapiens_hsa030400.78253217
95Platelet activation_Homo sapiens_hsa046110.77731206
96Notch signaling pathway_Homo sapiens_hsa043300.77244146
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76770864
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.74671798
99Focal adhesion_Homo sapiens_hsa045100.74073577
100Systemic lupus erythematosus_Homo sapiens_hsa053220.74024497
101Alcoholism_Homo sapiens_hsa050340.73972019
102HIF-1 signaling pathway_Homo sapiens_hsa040660.73543263
103Apoptosis_Homo sapiens_hsa042100.72539925
104Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72043796
105Malaria_Homo sapiens_hsa051440.71673829
106Basal transcription factors_Homo sapiens_hsa030220.71506108
107Insulin secretion_Homo sapiens_hsa049110.71367532
108Morphine addiction_Homo sapiens_hsa050320.71329746
109Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71148542
110Ras signaling pathway_Homo sapiens_hsa040140.70868438
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.70861541
112Insulin resistance_Homo sapiens_hsa049310.69990034
113Herpes simplex infection_Homo sapiens_hsa051680.69563691
114Cocaine addiction_Homo sapiens_hsa050300.69502363
115Gastric acid secretion_Homo sapiens_hsa049710.68991086
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.68482761
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68195332
118Pathways in cancer_Homo sapiens_hsa052000.68180788
119Rap1 signaling pathway_Homo sapiens_hsa040150.67416822
120Salivary secretion_Homo sapiens_hsa049700.66923997
121Hedgehog signaling pathway_Homo sapiens_hsa043400.66234528
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65972763
123Acute myeloid leukemia_Homo sapiens_hsa052210.65376655
124Lysine degradation_Homo sapiens_hsa003100.65060485
125Chemokine signaling pathway_Homo sapiens_hsa040620.64842167
126Amoebiasis_Homo sapiens_hsa051460.63739954
127Salmonella infection_Homo sapiens_hsa051320.63378605
128Toxoplasmosis_Homo sapiens_hsa051450.63141639
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62800568
130Melanoma_Homo sapiens_hsa052180.62489527
131Bladder cancer_Homo sapiens_hsa052190.60325569
132Primary immunodeficiency_Homo sapiens_hsa053400.58325714
133Fatty acid biosynthesis_Homo sapiens_hsa000610.53967263

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