EPSTI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1NIK/NF-kappaB signaling (GO:0038061)7.10239997
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.52988837
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.52988837
4antigen processing and presentation of endogenous antigen (GO:0019883)6.29992356
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.96432841
6positive regulation of gamma-delta T cell activation (GO:0046645)5.66272968
7negative T cell selection (GO:0043383)5.55985513
8negative thymic T cell selection (GO:0045060)5.52864128
9negative regulation of cell killing (GO:0031342)5.49805790
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.49805790
11T cell migration (GO:0072678)4.98103861
12positive regulation of type I interferon-mediated signaling pathway (GO:0060340)4.63404707
13regulation of interleukin-12 biosynthetic process (GO:0045075)4.62516717
14macrophage activation involved in immune response (GO:0002281)4.61671826
15negative regulation of interleukin-12 production (GO:0032695)4.57949369
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.56898409
17positive regulation by symbiont of host defense response (GO:0052509)4.48891348
18modulation by symbiont of host defense response (GO:0052031)4.48891348
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.48891348
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.48891348
21positive regulation by organism of defense response of other organism involved in symbiotic interact4.48891348
22modulation by symbiont of host immune response (GO:0052553)4.48891348
23regulation of RIG-I signaling pathway (GO:0039535)4.38151912
24myeloid dendritic cell activation (GO:0001773)4.36160058
25myeloid dendritic cell differentiation (GO:0043011)4.35888013
26response to interferon-alpha (GO:0035455)4.33173834
27regulation of gamma-delta T cell differentiation (GO:0045586)4.17179048
28negative regulation of viral genome replication (GO:0045071)4.07948510
29regulation of interferon-alpha production (GO:0032647)4.07924559
30response to peptidoglycan (GO:0032494)4.05249297
31thymic T cell selection (GO:0045061)4.04773441
32regulation of B cell receptor signaling pathway (GO:0050855)4.03762866
33detection of other organism (GO:0098543)3.94028770
34response to interferon-beta (GO:0035456)3.91635517
35regulation of gamma-delta T cell activation (GO:0046643)3.91034640
36positive thymic T cell selection (GO:0045059)3.87793744
37regulation of interferon-beta biosynthetic process (GO:0045357)3.87387835
38regulation of T cell tolerance induction (GO:0002664)3.85904661
39positive regulation of type 2 immune response (GO:0002830)3.85708406
40regulation of necroptotic process (GO:0060544)3.85353332
41regulation of alpha-beta T cell proliferation (GO:0046640)3.84282532
42interferon-gamma-mediated signaling pathway (GO:0060333)3.82889630
43cellular response to type I interferon (GO:0071357)3.81057230
44type I interferon signaling pathway (GO:0060337)3.81057230
45positive regulation of humoral immune response (GO:0002922)3.80222493
46response to type I interferon (GO:0034340)3.79901052
47detection of bacterium (GO:0016045)3.79006552
48T cell selection (GO:0045058)3.78786522
49cellular response to interleukin-15 (GO:0071350)3.75168820
50regulation of isotype switching to IgG isotypes (GO:0048302)3.74343962
51response to interleukin-15 (GO:0070672)3.72822005
52lymphocyte migration (GO:0072676)3.72665644
53positive regulation of antigen processing and presentation (GO:0002579)3.70766685
54neutrophil activation (GO:0042119)3.70311193
55natural killer cell mediated immunity (GO:0002228)3.70205511
56natural killer cell mediated cytotoxicity (GO:0042267)3.70205511
57cellular response to interferon-alpha (GO:0035457)3.70017219
58antigen processing and presentation via MHC class Ib (GO:0002475)3.67570666
59neutrophil activation involved in immune response (GO:0002283)3.65337929
60negative regulation of T cell mediated immunity (GO:0002710)3.65255378
61positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.64861483
62T-helper cell differentiation (GO:0042093)3.63001485
63CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.63001485
64regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.61921426
65regulation of response to interferon-gamma (GO:0060330)3.60833379
66positive regulation of natural killer cell differentiation (GO:0032825)3.60521445
67regulation of B cell differentiation (GO:0045577)3.58483790
68interferon-gamma production (GO:0032609)3.57896585
69positive regulation of isotype switching (GO:0045830)3.57494927
70B cell mediated immunity (GO:0019724)3.56859709
71necroptotic process (GO:0070266)3.52846100
72mature B cell differentiation (GO:0002335)3.51632056
73T cell differentiation involved in immune response (GO:0002292)3.51431795
74alpha-beta T cell differentiation involved in immune response (GO:0002293)3.51431795
75alpha-beta T cell activation involved in immune response (GO:0002287)3.51431795
76detection of molecule of bacterial origin (GO:0032490)3.50698365
77defense response to protozoan (GO:0042832)3.50675718
78positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.50107438
79regulation of T-helper 1 cell differentiation (GO:0045625)3.49911961
80response to muramyl dipeptide (GO:0032495)3.49798130
81granulocyte activation (GO:0036230)3.49459907
82regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.48844753
83regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.48788218
84negative regulation of necroptotic process (GO:0060546)3.48184800
85dendritic cell differentiation (GO:0097028)3.46983267
86microglial cell activation (GO:0001774)3.46543227
87cellular response to interferon-gamma (GO:0071346)3.45584301
88detection of external biotic stimulus (GO:0098581)3.45244440
89positive regulation of alpha-beta T cell proliferation (GO:0046641)3.44693630
90regulation of T cell receptor signaling pathway (GO:0050856)3.42392608
91regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.42151388
92regulation of natural killer cell mediated immunity (GO:0002715)3.42151388
93negative regulation of cytokine production involved in immune response (GO:0002719)3.41022945
94lipopolysaccharide-mediated signaling pathway (GO:0031663)3.40728763
95regulation of type I interferon-mediated signaling pathway (GO:0060338)3.37836524
96response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.37302682
97response to host immune response (GO:0052572)3.37302682
98Arp2/3 complex-mediated actin nucleation (GO:0034314)3.37206825
99positive regulation of interleukin-2 production (GO:0032743)3.36092994
100regulation of dendritic cell antigen processing and presentation (GO:0002604)3.35681914
101cellular response to interferon-beta (GO:0035458)3.33676623
102regulation of hypersensitivity (GO:0002883)3.32477982
103positive T cell selection (GO:0043368)3.32433134
104positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.32282494
105positive regulation of natural killer cell mediated immunity (GO:0002717)3.32282494
106positive regulation of B cell differentiation (GO:0045579)3.30172009
107response to interferon-gamma (GO:0034341)3.28732750
108response to protozoan (GO:0001562)3.28368411
109germinal center formation (GO:0002467)3.28028999
110regulation of antigen processing and presentation (GO:0002577)3.27187642
111myeloid cell activation involved in immune response (GO:0002275)3.24034791
112regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.22085592
113regulation of type 2 immune response (GO:0002828)3.21129646
114positive regulation of interferon-beta production (GO:0032728)3.20783340
115defense response to virus (GO:0051607)3.19717532
116natural killer cell activation (GO:0030101)3.17524500
117negative regulation of lymphocyte mediated immunity (GO:0002707)3.16452308
118regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.15295662
119positive regulation of T cell cytokine production (GO:0002726)3.15244426
120T cell activation involved in immune response (GO:0002286)3.14592975
121positive regulation of DNA recombination (GO:0045911)3.13836243
122positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.12036687
123T-helper 1 type immune response (GO:0042088)3.11693688
124B cell receptor signaling pathway (GO:0050853)3.10814000
125leukocyte aggregation (GO:0070486)3.10656108
126cellular response to zinc ion (GO:0071294)3.09928867
127immunoglobulin mediated immune response (GO:0016064)3.09734564
128alpha-beta T cell activation (GO:0046631)3.08422321
129sequestering of actin monomers (GO:0042989)3.07924703
130T cell costimulation (GO:0031295)3.07756235
131response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.07639667
132response to host (GO:0075136)3.07639667
133response to host defenses (GO:0052200)3.07639667
134regulation of leukocyte mediated cytotoxicity (GO:0001910)3.06816421
135positive regulation of toll-like receptor signaling pathway (GO:0034123)3.05860913
136T cell receptor signaling pathway (GO:0050852)3.04583380
137macrophage activation (GO:0042116)3.04267466
138lymphocyte chemotaxis (GO:0048247)3.04215672
139positive regulation of interleukin-12 production (GO:0032735)3.04129137
140positive regulation of interferon-alpha production (GO:0032727)3.03576934
141detection of biotic stimulus (GO:0009595)3.02722774
142lymphocyte costimulation (GO:0031294)3.02268756
143regulation of interleukin-12 production (GO:0032655)3.01657753
144positive regulation of immunoglobulin mediated immune response (GO:0002891)3.00773876
145positive regulation of B cell mediated immunity (GO:0002714)3.00773876
146negative regulation of innate immune response (GO:0045824)3.00706879
147regulation of tolerance induction (GO:0002643)2.98170205
148interferon-gamma secretion (GO:0072643)2.96675197
149cellular response to exogenous dsRNA (GO:0071360)2.96160643
150antigen receptor-mediated signaling pathway (GO:0050851)2.94460711
151regulation of MHC class I biosynthetic process (GO:0045343)2.93759344
152positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.91527306
153regulation of regulatory T cell differentiation (GO:0045589)2.88992314
154production of molecular mediator involved in inflammatory response (GO:0002532)2.87121820
155positive regulation of tolerance induction (GO:0002645)2.85869946
156negative regulation of leukocyte mediated immunity (GO:0002704)2.85463923
157regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.82947033
158regulation of viral genome replication (GO:0045069)2.81853171
159regulation of vitamin D biosynthetic process (GO:0060556)2.81848709
160regulation of chronic inflammatory response (GO:0002676)2.81583798

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* IRF8_22096565_ChIP-ChIP_GC-B_Human6.20580165
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.16012349
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.90475646
4* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.85075438
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.69467974
6* IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.32228783
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.56032459
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.42793184
9STAT4_19710469_ChIP-ChIP_TH1__Mouse3.34810575
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.25194277
11* IRF8_27001747_Chip-Seq_BMDM_Mouse3.17475350
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.87879959
13RUNX_20019798_ChIP-Seq_JUKART_Human2.83988189
14* MYB_26560356_Chip-Seq_TH2_Human2.80427045
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.79820733
16FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.76344054
17NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.64987382
18MAF_26560356_Chip-Seq_TH1_Human2.58855698
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.57884154
20E2F7_22180533_ChIP-Seq_HELA_Human2.53898059
21BP1_19119308_ChIP-ChIP_Hs578T_Human2.50843205
22MYB_26560356_Chip-Seq_TH1_Human2.41951951
23RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.41496875
24SPI1_23547873_ChIP-Seq_NB4_Human2.31774332
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.20039712
26MYC_22102868_ChIP-Seq_BL_Human2.18595200
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.17304188
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.12568862
29RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.11255608
30VDR_21846776_ChIP-Seq_THP-1_Human2.10034087
31GATA1_22025678_ChIP-Seq_K562_Human2.02264431
32SCL_19346495_ChIP-Seq_HPC-7_Human1.97458414
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.94479250
34UTX_26944678_Chip-Seq_JUKART_Human1.90683108
35VDR_24763502_ChIP-Seq_THP-1_Human1.88728641
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.87002959
37* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.81341187
38* GATA3_27048872_Chip-Seq_THYMUS_Human1.81083352
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.79292279
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.75313570
41TCF7_22412390_ChIP-Seq_EML_Mouse1.68036673
42E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.66935199
43VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.65629465
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.62386337
45MAF_26560356_Chip-Seq_TH2_Human1.61990646
46ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53837960
47Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.52117541
48SPI1_23127762_ChIP-Seq_K562_Human1.51631787
49MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.47615520
50PU_27001747_Chip-Seq_BMDM_Mouse1.46205855
51GATA3_26560356_Chip-Seq_TH2_Human1.42029544
52VDR_24787735_ChIP-Seq_THP-1_Human1.41631971
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38256256
54GATA2_22383799_ChIP-Seq_G1ME_Mouse1.38043005
55LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.36641620
56KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.34249954
57CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.25810285
58PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24603665
59LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.24320720
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23102126
61STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.22081347
62CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21042164
63* SMAD_19615063_ChIP-ChIP_OVARY_Human1.19903691
64ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18244345
65KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.15797521
66GATA1_19941826_ChIP-Seq_K562_Human1.15675618
67GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13169209
68PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12591619
69KDM2B_26808549_Chip-Seq_DND41_Human1.07748740
70GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07271910
71CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06559632
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05418593
73CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04211886
74CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99154029
75TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.99107402
76VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98827746
77KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96427682
78PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96294360
79TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96112154
80ELK3_25401928_ChIP-Seq_HUVEC_Human0.94870860
81GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93127352
82SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91400466
83* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90662680
84PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90063444
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89579036
86GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89254615
87STAT1_20625510_ChIP-Seq_HELA_Human0.86211222
88SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.85360639
89EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84024998
90GATA1_19941827_ChIP-Seq_MEL_Mouse0.83995362
91CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.83171185
92THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83047149
93BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.82049022
94GATA2_19941826_ChIP-Seq_K562_Human0.81574740
95* VDR_23849224_ChIP-Seq_CD4+_Human0.80938188
96RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.79742336
97EGR1_19032775_ChIP-ChIP_M12_Human0.79516787
98TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.78625215
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77453659
100GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77319723
101BCL6_27268052_Chip-Seq_Bcells_Human0.74024221
102SMRT_27268052_Chip-Seq_Bcells_Human0.71579252
103GATA1_19941827_ChIP-Seq_MEL86_Mouse0.71074843
104TP63_17297297_ChIP-ChIP_HaCaT_Human0.70232878
105FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.70114913
106GATA2_21666600_ChIP-Seq_HMVEC_Human0.69451494
107TFEB_21752829_ChIP-Seq_HELA_Human0.68701492
108FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.68568918
109BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.67035779
110BCOR_27268052_Chip-Seq_Bcells_Human0.66805081
111CTCF_26484167_Chip-Seq_Bcells_Mouse0.66362830
112SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.66289092
113E2F4_17652178_ChIP-ChIP_JURKAT_Human0.65836338
114CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.64334048
115NCOR1_26117541_ChIP-Seq_K562_Human0.61795663
116CIITA_25753668_ChIP-Seq_RAJI_Human0.59907803
117ETS1_22383799_ChIP-Seq_G1ME_Mouse0.59383629
118TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.58523216
119KDM2B_26808549_Chip-Seq_JURKAT_Human0.58486375

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.70844312
2MP0000685_abnormal_immune_system4.03128686
3MP0005671_abnormal_response_to3.81370210
4MP0002166_altered_tumor_susceptibility3.67659119
5MP0009785_altered_susceptibility_to3.28880552
6MP0001790_abnormal_immune_system3.24959769
7MP0005387_immune_system_phenotype3.24959769
8MP0002138_abnormal_hepatobiliary_system3.24445364
9MP0003763_abnormal_thymus_physiology3.09451300
10MP0001800_abnormal_humoral_immune3.08395920
11MP0002006_tumorigenesis3.03511204
12MP0005000_abnormal_immune_tolerance2.96638144
13MP0002148_abnormal_hypersensitivity_rea2.93319520
14MP0003436_decreased_susceptibility_to2.86910157
15MP0002452_abnormal_antigen_presenting2.76823081
16MP0004510_myositis2.75698403
17MP0002723_abnormal_immune_serum2.75375138
18MP0002009_preneoplasia2.75253304
19MP0001819_abnormal_immune_cell2.68085089
20MP0002420_abnormal_adaptive_immunity2.67937592
21MP0005025_abnormal_response_to2.63407404
22MP0002254_reproductive_system_inflammat2.51388458
23MP0002419_abnormal_innate_immunity2.37859778
24MP0001873_stomach_inflammation2.35467699
25MP0002398_abnormal_bone_marrow2.34995451
26MP0000716_abnormal_immune_system2.22150140
27MP0006082_CNS_inflammation2.14716211
28MP0002405_respiratory_system_inflammati2.09148770
29MP0005310_abnormal_salivary_gland1.98807605
30MP0002396_abnormal_hematopoietic_system1.97288365
31MP0009333_abnormal_splenocyte_physiolog1.96547654
32MP0001348_abnormal_lacrimal_gland1.95760689
33MP0004947_skin_inflammation1.84658710
34MP0003724_increased_susceptibility_to1.84019820
35MP0010155_abnormal_intestine_physiology1.83447868
36MP0000689_abnormal_spleen_morphology1.82030006
37MP0002429_abnormal_blood_cell1.80730330
38MP0002722_abnormal_immune_system1.80068339
39MP0005464_abnormal_platelet_physiology1.69227397
40MP0002163_abnormal_gland_morphology1.63825171
41MP0001853_heart_inflammation1.63822167
42MP0001845_abnormal_inflammatory_respons1.63687687
43MP0005451_abnormal_body_composition1.62054910
44MP0000703_abnormal_thymus_morphology1.61868778
45MP0008260_abnormal_autophagy1.51635985
46MP0003448_altered_tumor_morphology1.40980620
47MP0003075_altered_response_to1.39305920
48MP0000569_abnormal_digit_pigmentation1.39281015
49MP0002139_abnormal_hepatobiliary_system1.38666209
50MP0008004_abnormal_stomach_pH1.37578910
51MP0008469_abnormal_protein_level1.34944317
52MP0000858_altered_metastatic_potential1.34441510
53MP0003303_peritoneal_inflammation1.31084099
54MP0003866_abnormal_defecation1.29800442
55MP0005174_abnormal_tail_pigmentation1.29129418
56MP0004808_abnormal_hematopoietic_stem1.27891392
57MP0005397_hematopoietic_system_phenotyp1.25721961
58MP0001545_abnormal_hematopoietic_system1.25721961
59MP0001533_abnormal_skeleton_physiology1.24476926
60MP0002877_abnormal_melanocyte_morpholog1.23829304
61MP0002933_joint_inflammation1.23634931
62MP0002277_abnormal_respiratory_mucosa1.20972647
63MP0003300_gastrointestinal_ulcer1.20514830
64MP0003690_abnormal_glial_cell1.11287018
65MP0004883_abnormal_blood_vessel1.05345571
66MP0003806_abnormal_nucleotide_metabolis1.04885647
67MP0009764_decreased_sensitivity_to1.02648117
68MP0005164_abnormal_response_to1.01340407
69MP0005058_abnormal_lysosome_morphology1.00928874
70MP0002019_abnormal_tumor_incidence0.92160198
71MP0002998_abnormal_bone_remodeling0.92060509
72MP0010352_gastrointestinal_tract_polyps0.91009882
73MP0002332_abnormal_exercise_endurance0.90467863
74MP0006054_spinal_hemorrhage0.90247186
75MP0003656_abnormal_erythrocyte_physiolo0.90177768
76MP0000490_abnormal_crypts_of0.87617668
77MP0003191_abnormal_cellular_cholesterol0.84617681
78MP0009840_abnormal_foam_cell0.84374102
79MP0003453_abnormal_keratinocyte_physiol0.84035016
80MP0001346_abnormal_lacrimal_gland0.79429467
81MP0005390_skeleton_phenotype0.79103782
82MP0005379_endocrine/exocrine_gland_phen0.78402084
83MP0005075_abnormal_melanosome_morpholog0.77452443
84MP0003172_abnormal_lysosome_physiology0.77131040
85MP0010307_abnormal_tumor_latency0.76916556
86MP0003828_pulmonary_edema0.76543881
87MP0008057_abnormal_DNA_replication0.75539643
88MP0000015_abnormal_ear_pigmentation0.71670283
89MP0003195_calcinosis0.70383733
90MP0003183_abnormal_peptide_metabolism0.70082629
91MP0009278_abnormal_bone_marrow0.69489497
92MP0005076_abnormal_cell_differentiation0.69397792
93MP0003045_fibrosis0.69161254
94MP0009763_increased_sensitivity_to0.68509048
95MP0003091_abnormal_cell_migration0.68166469
96MP0000371_diluted_coat_color0.67671375
97MP0002095_abnormal_skin_pigmentation0.66568497
98MP0000465_gastrointestinal_hemorrhage0.66344955
99MP0008874_decreased_physiological_sensi0.64245778
100MP0008007_abnormal_cellular_replicative0.62575430
101MP0002136_abnormal_kidney_physiology0.62319955
102MP0000604_amyloidosis0.59398094
103MP0000249_abnormal_blood_vessel0.59295433
104MP0001851_eye_inflammation0.58866115
105MP0003795_abnormal_bone_structure0.58368755
106MP0005319_abnormal_enzyme/_coenzyme0.56080252
107MP0002132_abnormal_respiratory_system0.54858778
108MP0001881_abnormal_mammary_gland0.54457130
109MP0005023_abnormal_wound_healing0.54155093
110MP0001243_abnormal_dermal_layer0.54148060
111MP0005167_abnormal_blood-brain_barrier0.53166899
112MP0001663_abnormal_digestive_system0.52508695
113MP0005381_digestive/alimentary_phenotyp0.50923935
114MP0009765_abnormal_xenobiotic_induced0.50429948
115MP0003943_abnormal_hepatobiliary_system0.49421872
116MP0000313_abnormal_cell_death0.48450832
117MP0005165_increased_susceptibility_to0.48436463
118MP0005535_abnormal_body_temperature0.48397226
119MP0000343_altered_response_to0.47674661
120MP0000609_abnormal_liver_physiology0.45811482
121MP0005166_decreased_susceptibility_to0.45115494
122MP0004381_abnormal_hair_follicle0.43155665
123MP0001191_abnormal_skin_condition0.42242993

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of T cell number (HP:0011839)5.12722922
2Recurrent abscess formation (HP:0002722)5.09884467
3Myositis (HP:0100614)5.09693852
4Recurrent viral infections (HP:0004429)4.96809991
5Chronic otitis media (HP:0000389)4.96043634
6Elevated erythrocyte sedimentation rate (HP:0003565)4.86987565
7Recurrent bacterial skin infections (HP:0005406)4.82863703
8Recurrent fungal infections (HP:0002841)4.82672402
9T lymphocytopenia (HP:0005403)4.82670050
10Eczematoid dermatitis (HP:0000976)4.69963596
11Nasal polyposis (HP:0100582)4.43167014
12Retrobulbar optic neuritis (HP:0100654)4.30040016
13Optic neuritis (HP:0100653)4.30040016
14Abnormal delayed hypersensitivity skin test (HP:0002963)4.26170335
15Recurrent bronchitis (HP:0002837)4.13295545
16Orchitis (HP:0100796)4.06292377
17Thrombocytosis (HP:0001894)4.02747756
18Autoimmune thrombocytopenia (HP:0001973)3.98768398
19Increased IgM level (HP:0003496)3.97903112
20Abnormality of T cells (HP:0002843)3.96283719
21Abnormality of the nasal mucosa (HP:0000433)3.85496815
22Mediastinal lymphadenopathy (HP:0100721)3.81462959
23Recurrent cutaneous fungal infections (HP:0011370)3.73987300
24Chronic mucocutaneous candidiasis (HP:0002728)3.73987300
25Panhypogammaglobulinemia (HP:0003139)3.71590201
26Recurrent skin infections (HP:0001581)3.62597495
27Eosinophilia (HP:0001880)3.56744112
28Vasculitis (HP:0002633)3.54428465
29Severe combined immunodeficiency (HP:0004430)3.50435646
30Leukocytosis (HP:0001974)3.43389444
31Fatigue (HP:0012378)3.43038344
32Abnormality of eosinophils (HP:0001879)3.40894580
33Agammaglobulinemia (HP:0004432)3.39791413
34Thyroiditis (HP:0100646)3.39245413
35Combined immunodeficiency (HP:0005387)3.36448783
36Autoimmune hemolytic anemia (HP:0001890)3.36108047
37Pulmonary infiltrates (HP:0002113)3.33898739
38Meningitis (HP:0001287)3.31822374
39Systemic lupus erythematosus (HP:0002725)3.31659651
40Gastrointestinal infarctions (HP:0005244)3.29812387
41Abnormality of liposaccharide metabolism (HP:0010968)3.27130849
42Abnormality of glycosphingolipid metabolism (HP:0004343)3.27130849
43Abnormality of glycolipid metabolism (HP:0010969)3.27130849
44Arterial thrombosis (HP:0004420)3.24367208
45Granulocytopenia (HP:0001913)3.20158752
46Hypergammaglobulinemia (HP:0010702)3.20085339
47Increased IgE level (HP:0003212)3.19251041
48Inflammation of the large intestine (HP:0002037)3.16281534
49Abnormality of macrophages (HP:0004311)3.14868132
50IgG deficiency (HP:0004315)3.13133473
51Abnormality of T cell physiology (HP:0011840)3.10441531
52Abnormality of the fingertips (HP:0001211)3.08217428
53Encephalitis (HP:0002383)3.07833918
54Gastrointestinal inflammation (HP:0004386)3.02580075
55Colitis (HP:0002583)2.98916805
56Recurrent gram-negative bacterial infections (HP:0005420)2.98047850
57IgM deficiency (HP:0002850)2.95840351
58Keratoconjunctivitis sicca (HP:0001097)2.88358947
59Loss of speech (HP:0002371)2.87025895
60Spontaneous hematomas (HP:0007420)2.85446102
61Abnormality of cells of the lymphoid lineage (HP:0012140)2.84506342
62Urticaria (HP:0001025)2.84347615
63Chronic diarrhea (HP:0002028)2.84083835
64Gangrene (HP:0100758)2.82964113
65Pustule (HP:0200039)2.79532294
66Obstructive lung disease (HP:0006536)2.78649593
67Chronic obstructive pulmonary disease (HP:0006510)2.78649593
68Malnutrition (HP:0004395)2.77559546
69Lymphopenia (HP:0001888)2.76481535
70Periodontitis (HP:0000704)2.75753418
71Hemoptysis (HP:0002105)2.72697811
72Keratoconjunctivitis (HP:0001096)2.70491474
73B lymphocytopenia (HP:0010976)2.67257638
74Abnormality of B cell number (HP:0010975)2.67257638
75Joint swelling (HP:0001386)2.66810263
76Chronic sinusitis (HP:0011109)2.65610079
77Anorexia (HP:0002039)2.52288886
78Stomatitis (HP:0010280)2.51796344
79Gingival bleeding (HP:0000225)2.51263158
80Abnormality of the pleura (HP:0002103)2.48598739
81Cellulitis (HP:0100658)2.47241718
82Gingivitis (HP:0000230)2.45620804
83Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.43922623
84Chest pain (HP:0100749)2.39719151
85Hematochezia (HP:0002573)2.38671681
86Amyloidosis (HP:0011034)2.37916216
87Peritonitis (HP:0002586)2.33383209
88Amaurosis fugax (HP:0100576)2.33379218
89Bronchitis (HP:0012387)2.32609663
90Interstitial pulmonary disease (HP:0006530)2.32292853
91Polyneuropathy (HP:0001271)2.31741534
92Episodic fever (HP:0001954)2.31555853
93Epistaxis (HP:0000421)2.30724123
94Disinhibition (HP:0000734)2.30550846
95Dysostosis multiplex (HP:0000943)2.24177192
96Purpura (HP:0000979)2.23171462
97Basal ganglia calcification (HP:0002135)2.21231740
98Petechiae (HP:0000967)2.19958036
99Abnormality of the pericardium (HP:0001697)2.19268430
100Acute myeloid leukemia (HP:0004808)2.19124687
101Increased serum ferritin (HP:0003281)2.17373477
102Abnormality of the prostate (HP:0008775)2.16363108
103Polycythemia (HP:0001901)2.14336833
104Recurrent sinusitis (HP:0011108)2.13617369
105Glomerulopathy (HP:0100820)2.13439723
106Premature loss of primary teeth (HP:0006323)2.12822371
107IgA deficiency (HP:0002720)2.10337024
108Abnormality of the endocardium (HP:0004306)2.10212610
109Lymphoma (HP:0002665)2.10127331
110Myocardial infarction (HP:0001658)2.09671127
111Hypoplasia of the thymus (HP:0000778)2.07875012
112Vertigo (HP:0002321)2.07773353
113Skin rash (HP:0000988)2.06235611
114Arthralgia (HP:0002829)2.05411310
115Abnormality of iron homeostasis (HP:0011031)2.03816115
116Verrucae (HP:0200043)2.01016785
117Papilloma (HP:0012740)2.01016785
118Pulmonary embolism (HP:0002204)2.00806199
119Emphysema (HP:0002097)2.00312354
120Increased cerebral lipofuscin (HP:0011813)1.99670143
121Thrombophlebitis (HP:0004418)1.98975590
122Abnormality of the peritoneum (HP:0002585)1.98823767
123Recurrent pneumonia (HP:0006532)1.98004373
124Skin ulcer (HP:0200042)1.96563327
125Recurrent lower respiratory tract infections (HP:0002783)1.95363995
126Gastrointestinal stroma tumor (HP:0100723)1.94935212
127Vacuolated lymphocytes (HP:0001922)1.94089148
128Exertional dyspnea (HP:0002875)1.91338785
129Osteomyelitis (HP:0002754)1.90808224
130Prolonged bleeding time (HP:0003010)1.87890194

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.70923302
2TYK23.76690876
3MAP4K13.70806215
4JAK33.63009356
5TXK3.27414759
6MAP3K133.19513714
7TBK13.14012465
8IKBKE3.11489498
9IKBKB2.88287349
10IRAK42.66562950
11JAK12.65542241
12KIT2.46648396
13ZAP702.31221408
14FLT32.12911578
15ERN12.12010429
16CHUK1.98375111
17FGFR41.96778329
18MATK1.90494715
19PRPF4B1.90475022
20ITK1.89626863
21BLK1.85093442
22NLK1.80716532
23GRK71.78501270
24TEC1.73925360
25GRK61.69767507
26SYK1.68153675
27BTK1.66817196
28CSF1R1.65408240
29LCK1.53477062
30NME21.52811806
31FGFR31.51204310
32CSK1.48931449
33RIPK11.44855879
34STK101.39848170
35TAOK21.37315520
36EPHB11.35553199
37MAP3K31.35099309
38MAP3K111.31358114
39MST41.26775213
40TAOK31.24409857
41TAOK11.19806670
42RIPK41.14933500
43PIM11.12122913
44HCK1.07896348
45MAP3K11.03603999
46RPS6KA41.01636643
47JAK21.00850068
48NEK90.99031235
49EPHA30.98459972
50CDC42BPA0.98129781
51MAP3K100.97063100
52PRKAA20.95706225
53ACVR1B0.94102812
54LRRK20.93430004
55PIM20.89189193
56LYN0.84981616
57IRAK10.81362332
58IRAK30.79859342
59PRKCQ0.77322393
60SIK20.77089056
61PIK3CG0.75099577
62SIK30.73865666
63TGFBR10.73584823
64CLK10.71264349
65PKN10.71240270
66BMPR20.68308266
67STK40.68164676
68MAP3K50.67087754
69MAP2K60.65196369
70DDR20.64212253
71KDR0.63374105
72PDK10.63251454
73TGFBR20.61893509
74FES0.59859529
75MAPKAPK20.58896367
76MAP2K30.55212345
77TLK10.55066969
78PTK60.54834660
79HIPK20.52921470
80MELK0.50520592
81TESK20.47329186
82NUAK10.46702974
83MAPK70.46225647
84PDPK10.46216385
85CDK90.45926967
86PRKCD0.45321145
87ADRBK20.43255762
88EIF2AK20.42769333
89KSR20.42323320
90RAF10.42251309
91MAP3K120.41345341
92TRPM70.40522233
93ABL10.40330615
94EEF2K0.39940952
95ARAF0.38399890
96MOS0.38218285
97MAP3K70.38029943
98RPS6KA50.37674449
99STK240.37105918
100CDK40.32761549
101RPS6KA60.31275113
102FGR0.31098264
103YES10.30447077
104TNK20.29141396
105MAPK110.29029563
106RET0.28595896
107MARK20.28237528
108MARK30.26687302
109PTK2B0.26017327
110BMX0.25683644
111NEK20.24381492
112RPS6KA10.23720438
113MAP3K60.22691891
114EGFR0.22666536
115IRAK20.22595804
116SMG10.22164936
117PRKD20.21867893
118TTN0.21603820
119MAP3K80.19842201
120DYRK1B0.19409119
121MAPK30.18985458
122CDK60.18807840
123PKN20.18596006
124INSR0.18156338
125BMPR1B0.17562760
126MAPK40.17540850
127KSR10.16985443
128IGF1R0.16544699
129AKT10.16533172
130FYN0.16185910
131BRAF0.13164725

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.64332068
2Graft-versus-host disease_Homo sapiens_hsa053323.62333111
3NF-kappa B signaling pathway_Homo sapiens_hsa040643.26634602
4Allograft rejection_Homo sapiens_hsa053303.26573549
5Antigen processing and presentation_Homo sapiens_hsa046122.97872918
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.91778332
7Leishmaniasis_Homo sapiens_hsa051402.80156597
8Measles_Homo sapiens_hsa051622.72384882
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.38481331
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.37300641
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.34219419
12T cell receptor signaling pathway_Homo sapiens_hsa046602.22886837
13Osteoclast differentiation_Homo sapiens_hsa043802.18468275
14NOD-like receptor signaling pathway_Homo sapiens_hsa046212.18099115
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.16778389
16Toll-like receptor signaling pathway_Homo sapiens_hsa046202.01026073
17B cell receptor signaling pathway_Homo sapiens_hsa046621.97937589
18Herpes simplex infection_Homo sapiens_hsa051681.95526950
19Autoimmune thyroid disease_Homo sapiens_hsa053201.89667933
20Toxoplasmosis_Homo sapiens_hsa051451.89194041
21TNF signaling pathway_Homo sapiens_hsa046681.82344643
22Jak-STAT signaling pathway_Homo sapiens_hsa046301.79613542
23Apoptosis_Homo sapiens_hsa042101.69989579
24Influenza A_Homo sapiens_hsa051641.66554770
25Hematopoietic cell lineage_Homo sapiens_hsa046401.63524650
26Type I diabetes mellitus_Homo sapiens_hsa049401.62970275
27Chemokine signaling pathway_Homo sapiens_hsa040621.61369055
28Viral myocarditis_Homo sapiens_hsa054161.53693982
29Shigellosis_Homo sapiens_hsa051311.42930891
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38911597
31Legionellosis_Homo sapiens_hsa051341.37972061
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.33144119
33Tuberculosis_Homo sapiens_hsa051521.31061520
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.30960631
35Pertussis_Homo sapiens_hsa051331.28841628
36Staphylococcus aureus infection_Homo sapiens_hsa051501.23058421
37Malaria_Homo sapiens_hsa051441.22792837
38Hepatitis B_Homo sapiens_hsa051611.19507164
39Acute myeloid leukemia_Homo sapiens_hsa052211.19428761
40Epstein-Barr virus infection_Homo sapiens_hsa051691.11230895
41Ribosome_Homo sapiens_hsa030101.08041312
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.01904339
43Hepatitis C_Homo sapiens_hsa051601.00615004
44Salmonella infection_Homo sapiens_hsa051321.00410815
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.97899756
46Small cell lung cancer_Homo sapiens_hsa052220.93031726
47Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92989490
48p53 signaling pathway_Homo sapiens_hsa041150.88474671
49African trypanosomiasis_Homo sapiens_hsa051430.88422116
50Rheumatoid arthritis_Homo sapiens_hsa053230.87573544
51Pancreatic cancer_Homo sapiens_hsa052120.85382951
52Prolactin signaling pathway_Homo sapiens_hsa049170.85099758
53Chronic myeloid leukemia_Homo sapiens_hsa052200.84600606
54Asthma_Homo sapiens_hsa053100.81862623
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80554910
56HTLV-I infection_Homo sapiens_hsa051660.77248093
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.76210667
58Viral carcinogenesis_Homo sapiens_hsa052030.75041772
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.73949328
60Platelet activation_Homo sapiens_hsa046110.72543397
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69415414
62Non-homologous end-joining_Homo sapiens_hsa034500.68794335
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68518650
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.65839110
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.53636655
66Other glycan degradation_Homo sapiens_hsa005110.52432205
67Dorso-ventral axis formation_Homo sapiens_hsa043200.52228961
68Proteasome_Homo sapiens_hsa030500.50250352
69DNA replication_Homo sapiens_hsa030300.50205608
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49327668
71Base excision repair_Homo sapiens_hsa034100.46192513
72VEGF signaling pathway_Homo sapiens_hsa043700.42879832
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.41914780
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40045502
75Colorectal cancer_Homo sapiens_hsa052100.38072500
76Lysosome_Homo sapiens_hsa041420.37855410
77Complement and coagulation cascades_Homo sapiens_hsa046100.36920373
78FoxO signaling pathway_Homo sapiens_hsa040680.31578001
79Non-small cell lung cancer_Homo sapiens_hsa052230.31427131
80MAPK signaling pathway_Homo sapiens_hsa040100.30324089
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30230181
82HIF-1 signaling pathway_Homo sapiens_hsa040660.29862362
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29159949
84Type II diabetes mellitus_Homo sapiens_hsa049300.28745092
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.28452342
86Systemic lupus erythematosus_Homo sapiens_hsa053220.28011974
87Notch signaling pathway_Homo sapiens_hsa043300.27887486
88MicroRNAs in cancer_Homo sapiens_hsa052060.27749863
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27611287
90Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.27410734
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27081781
92Endocytosis_Homo sapiens_hsa041440.26969331
93Insulin resistance_Homo sapiens_hsa049310.26755539
94Homologous recombination_Homo sapiens_hsa034400.26511729
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.25162152
96Caffeine metabolism_Homo sapiens_hsa002320.24832553
97SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23914080
98Bladder cancer_Homo sapiens_hsa052190.23754482
99Renal cell carcinoma_Homo sapiens_hsa052110.23717664
100Pathways in cancer_Homo sapiens_hsa052000.23686158
101Prion diseases_Homo sapiens_hsa050200.20718370
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.20236882
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18855504
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.17325068
105Renin-angiotensin system_Homo sapiens_hsa046140.15950886
106Sphingolipid metabolism_Homo sapiens_hsa006000.15716373
107Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.14051073
108Mismatch repair_Homo sapiens_hsa034300.13509998
109Phagosome_Homo sapiens_hsa041450.12888513
110Amoebiasis_Homo sapiens_hsa051460.12823093
111Prostate cancer_Homo sapiens_hsa052150.11755846
112Thyroid cancer_Homo sapiens_hsa052160.10373546
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10338700
114ABC transporters_Homo sapiens_hsa020100.09086440
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.08979663
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.08608246
117Regulation of autophagy_Homo sapiens_hsa041400.08282938
118Collecting duct acid secretion_Homo sapiens_hsa049660.07773360
119Arachidonic acid metabolism_Homo sapiens_hsa005900.07567968

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