ERGIC3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)4.75521383
2COPI coating of Golgi vesicle (GO:0048205)4.75521383
3signal peptide processing (GO:0006465)4.55611497
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.46626299
5protein retention in ER lumen (GO:0006621)4.43601734
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.36905272
7proline biosynthetic process (GO:0006561)4.18651013
8axonemal dynein complex assembly (GO:0070286)4.17332733
9energy coupled proton transport, down electrochemical gradient (GO:0015985)4.09896408
10ATP synthesis coupled proton transport (GO:0015986)4.09896408
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.66636030
12ATP hydrolysis coupled proton transport (GO:0015991)3.61719377
13energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.61719377
14protein complex biogenesis (GO:0070271)3.61144351
15ribosomal small subunit assembly (GO:0000028)3.43492051
16chaperone-mediated protein transport (GO:0072321)3.39855792
17keratan sulfate catabolic process (GO:0042340)3.36285763
18amyloid precursor protein catabolic process (GO:0042987)3.35511794
19viral transcription (GO:0019083)3.35300475
204-hydroxyproline metabolic process (GO:0019471)3.33535367
21mitochondrial respiratory chain complex I assembly (GO:0032981)3.23678432
22NADH dehydrogenase complex assembly (GO:0010257)3.23678432
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.23678432
24respiratory electron transport chain (GO:0022904)3.20956176
25regulation of oxidative phosphorylation (GO:0002082)3.18402654
26aldehyde catabolic process (GO:0046185)3.17805133
27cullin deneddylation (GO:0010388)3.17223550
28electron transport chain (GO:0022900)3.16785757
29mitochondrial respiratory chain complex assembly (GO:0033108)3.14948812
30formation of translation preinitiation complex (GO:0001731)3.14237513
31translational termination (GO:0006415)3.13615954
32cellular copper ion homeostasis (GO:0006878)3.09808068
33erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.08015852
34L-phenylalanine metabolic process (GO:0006558)3.08015852
35transferrin transport (GO:0033572)3.06816950
36GTP biosynthetic process (GO:0006183)3.04625669
37left/right pattern formation (GO:0060972)3.01553173
38NADH metabolic process (GO:0006734)3.01458526
39protein deneddylation (GO:0000338)2.99683066
40proline metabolic process (GO:0006560)2.98810284
41protein neddylation (GO:0045116)2.97911311
42regulation of cholesterol esterification (GO:0010872)2.97316134
43peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.95746182
44translational elongation (GO:0006414)2.94973499
45mannosylation (GO:0097502)2.94704705
46regulation of cholesterol biosynthetic process (GO:0045540)2.93160815
47ferric iron transport (GO:0015682)2.91602069
48trivalent inorganic cation transport (GO:0072512)2.91602069
49cilium movement (GO:0003341)2.90360613
50hydrogen peroxide catabolic process (GO:0042744)2.86236686
51mitotic nuclear envelope reassembly (GO:0007084)2.83956579
52nuclear envelope reassembly (GO:0031468)2.83956579
53peptidyl-proline hydroxylation (GO:0019511)2.83924541
54negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.78963182
55viral life cycle (GO:0019058)2.76226928
56epithelial cilium movement (GO:0003351)2.75704352
57motile cilium assembly (GO:0044458)2.74626163
58COPII vesicle coating (GO:0048208)2.72292049
59guanosine-containing compound biosynthetic process (GO:1901070)2.71352424
60pentose-phosphate shunt (GO:0006098)2.69754009
61GDP-mannose metabolic process (GO:0019673)2.68369398
62fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.68347222
63NADPH regeneration (GO:0006740)2.67398589
64glucose catabolic process (GO:0006007)2.65635851
65tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.65209897
66RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.65209897
67nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.64838748
68antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.63243052
69purine nucleoside triphosphate biosynthetic process (GO:0009145)2.62004881
70regulation of cellular amino acid metabolic process (GO:0006521)2.61069228
71dopamine transport (GO:0015872)2.60900365
72translational initiation (GO:0006413)2.60680513
73glutamine family amino acid biosynthetic process (GO:0009084)2.60539499
74purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.60043832
75desmosome organization (GO:0002934)2.58985231
76L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.55679014
77hydrogen ion transmembrane transport (GO:1902600)2.55069205
78glutathione derivative metabolic process (GO:1901685)2.54860647
79glutathione derivative biosynthetic process (GO:1901687)2.54860647
80viral protein processing (GO:0019082)2.54308887
81cellular protein complex disassembly (GO:0043624)2.53471456
82establishment of integrated proviral latency (GO:0075713)2.52838099
83primary alcohol catabolic process (GO:0034310)2.52223606
84response to misfolded protein (GO:0051788)2.52143281
85copper ion homeostasis (GO:0055070)2.49517529
86regulation of cellular respiration (GO:0043457)2.48776953
87protein targeting to membrane (GO:0006612)2.48510329
88glycoside metabolic process (GO:0016137)2.48326688
89retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.47569478
90ATP biosynthetic process (GO:0006754)2.47306164
91activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.45858369
92peptide catabolic process (GO:0043171)2.45318147
93adhesion of symbiont to host cell (GO:0044650)2.44282722
94virion attachment to host cell (GO:0019062)2.44282722
95protein hydroxylation (GO:0018126)2.43397446
96intraciliary transport (GO:0042073)2.43138059
97ribosomal large subunit biogenesis (GO:0042273)2.42495932
98pentose metabolic process (GO:0019321)2.42452965
99UTP metabolic process (GO:0046051)2.42452673
100basement membrane organization (GO:0071711)2.42173177
101cotranslational protein targeting to membrane (GO:0006613)2.41768780
102negative regulation of complement activation (GO:0045916)2.41034527
103vesicle coating (GO:0006901)2.40737636
104DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.39503061
105positive regulation of nuclease activity (GO:0032075)2.39159352
106ribosomal small subunit biogenesis (GO:0042274)2.39125967
107regulation of cilium movement (GO:0003352)2.38901490
108positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.37370760
109succinate metabolic process (GO:0006105)2.36871053
110establishment of viral latency (GO:0019043)2.36627538
111proton transport (GO:0015992)2.36357585
112dermatan sulfate biosynthetic process (GO:0030208)2.36189714
113UTP biosynthetic process (GO:0006228)2.36019726
114exocrine pancreas development (GO:0031017)2.35979022
115antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.35661539
116SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.35506940
117signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.35394972
118intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.35394972
119vitamin transmembrane transport (GO:0035461)2.34674708
120regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.34547274
121regulation of mitochondrial translation (GO:0070129)2.34163638
122cilium or flagellum-dependent cell motility (GO:0001539)2.33764065
123CTP metabolic process (GO:0046036)2.33621613
124CTP biosynthetic process (GO:0006241)2.33621613
125protein targeting to ER (GO:0045047)2.33595402
126plasma lipoprotein particle assembly (GO:0034377)2.33583190
127phagosome maturation (GO:0090382)2.32709502
128hydrogen transport (GO:0006818)2.32650908
129virion assembly (GO:0019068)2.32052739
130protein maturation by protein folding (GO:0022417)2.31553400
131dermatan sulfate metabolic process (GO:0030205)2.31382480
132oxaloacetate metabolic process (GO:0006107)2.30771781
133signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.30379869
134signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.30379869
135signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.30379869
136protein localization to endoplasmic reticulum (GO:0070972)2.30163935
137ribonucleoside triphosphate biosynthetic process (GO:0009201)2.29527573
138lung epithelium development (GO:0060428)2.28963629
139signal transduction involved in DNA damage checkpoint (GO:0072422)2.27857953
140signal transduction involved in DNA integrity checkpoint (GO:0072401)2.27857953
141extracellular fibril organization (GO:0043206)2.27782112
142protein complex disassembly (GO:0043241)2.27713136
143fatty acid elongation (GO:0030497)2.27441191
144negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.27260351
145adhesion of symbiont to host (GO:0044406)2.27097274
146positive regulation of amino acid transport (GO:0051957)2.26949722
147inner mitochondrial membrane organization (GO:0007007)2.23117069
148antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.23096221
149type B pancreatic cell proliferation (GO:0044342)2.22397809
150negative regulation of ligase activity (GO:0051352)2.21918917
151negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.21918917
152protein N-linked glycosylation via asparagine (GO:0018279)2.21764250
153L-phenylalanine catabolic process (GO:0006559)2.21437972
154erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.21437972
155ER overload response (GO:0006983)2.21201466
156fucose metabolic process (GO:0006004)2.20706774
157regulation of penile erection (GO:0060405)2.20304857
158cell redox homeostasis (GO:0045454)2.20033747
159respiratory chain complex IV assembly (GO:0008535)2.18960134
160proteasome assembly (GO:0043248)2.18761922
161cellular iron ion homeostasis (GO:0006879)2.17316213
162regulation of metalloenzyme activity (GO:0048552)2.17256748
163dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.16442685
164peptidyl-asparagine modification (GO:0018196)2.15993423
165establishment of protein localization to endoplasmic reticulum (GO:0072599)2.15791284

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.54098370
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.24964430
3PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.84081858
4MYC_18555785_ChIP-Seq_MESCs_Mouse2.60135151
5ZNF263_19887448_ChIP-Seq_K562_Human2.59666706
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.43359748
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.40148430
8PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.32094608
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.30106438
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.29035743
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.27300371
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.23881484
13HIF1A_21447827_ChIP-Seq_MCF-7_Human2.22156546
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.20274590
15TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.18743044
16RARG_19884340_ChIP-ChIP_MEFs_Mouse2.18006692
17XRN2_22483619_ChIP-Seq_HELA_Human2.14707148
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.06473865
19TP63_17297297_ChIP-ChIP_HaCaT_Human2.02469515
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.00078912
21SRF_21415370_ChIP-Seq_HL-1_Mouse1.98656026
22EST1_17652178_ChIP-ChIP_JURKAT_Human1.95204914
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.89856940
24DCP1A_22483619_ChIP-Seq_HELA_Human1.88104076
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.85090133
26* GABP_19822575_ChIP-Seq_HepG2_Human1.83573147
27DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.82234807
28MYC_19079543_ChIP-ChIP_MESCs_Mouse1.78001877
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.77678310
30CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.77090439
31SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.74191375
32SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.73923062
33MYC_19030024_ChIP-ChIP_MESCs_Mouse1.73690546
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.73040462
35ZFX_18555785_ChIP-Seq_MESCs_Mouse1.71346938
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.69452553
37ESR1_15608294_ChIP-ChIP_MCF-7_Human1.68211311
38PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.68173241
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.68042330
40ETS1_20019798_ChIP-Seq_JURKAT_Human1.67023030
41RACK7_27058665_Chip-Seq_MCF-7_Human1.66194653
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65363353
43CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.65361732
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.60934287
45CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.60246104
46SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.59409473
47FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.55954470
48E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.53928789
49TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52949176
50EZH2_27304074_Chip-Seq_ESCs_Mouse1.50576000
51SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.49465745
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.49010387
53TTF2_22483619_ChIP-Seq_HELA_Human1.45502687
54KDM5A_27292631_Chip-Seq_BREAST_Human1.44444734
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.39702880
56DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.39177906
57CLOCK_20551151_ChIP-Seq_293T_Human1.37507750
58LXR_22292898_ChIP-Seq_THP-1_Human1.37194718
59SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.36782744
60ERG_21242973_ChIP-ChIP_JURKAT_Human1.36210018
61CTBP2_25329375_ChIP-Seq_LNCAP_Human1.35682231
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.34889067
63CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.34777319
64KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.34673595
65POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.34577552
66MTF2_20144788_ChIP-Seq_MESCs_Mouse1.33781764
67EZH2_27294783_Chip-Seq_ESCs_Mouse1.33552962
68CTCF_18555785_ChIP-Seq_MESCs_Mouse1.33112471
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.32809176
70ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.32374268
71BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31764909
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.31371069
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.30752928
74EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.30542073
75THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29081767
76SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28385632
77RNF2_18974828_ChIP-Seq_MESCs_Mouse1.27760524
78EZH2_18974828_ChIP-Seq_MESCs_Mouse1.27760524
79STAT3_1855785_ChIP-Seq_MESCs_Mouse1.25606790
80ELK3_25401928_ChIP-Seq_HUVEC_Human1.25016938
81SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.24546914
82RXR_22158963_ChIP-Seq_LIVER_Mouse1.24127231
83YY1_21170310_ChIP-Seq_MESCs_Mouse1.23241009
84NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.23178056
85TP53_20018659_ChIP-ChIP_R1E_Mouse1.22201124
86* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21980785
87ESR2_21235772_ChIP-Seq_MCF-7_Human1.21774238
88TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.21313748
89CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.21120976
90CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20424082
91TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.20197403
92ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.19614731
93ATF3_27146783_Chip-Seq_COLON_Human1.19133217
94RAD21_21589869_ChIP-Seq_MESCs_Mouse1.17849316
95* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17798869
96NANOG_18555785_ChIP-Seq_MESCs_Mouse1.17355029
97CBX2_27304074_Chip-Seq_ESCs_Mouse1.16452337
98ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15988822
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14276268
100THAP11_20581084_ChIP-Seq_MESCs_Mouse1.13573951
101ELF1_20517297_ChIP-Seq_JURKAT_Human1.13154264
102SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.13094299
103ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.11616553
104TFEB_21752829_ChIP-Seq_HELA_Human1.11004911
105KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10295773
106PPARA_22158963_ChIP-Seq_LIVER_Mouse1.09481166
107CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.09232382
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.09113285
109* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.08989423
110FOXP1_21924763_ChIP-Seq_HESCs_Human1.08986803
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05863554
112ELF1_17652178_ChIP-ChIP_JURKAT_Human1.04884148
113NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03809895
114SOX17_20123909_ChIP-Seq_XEN_Mouse1.03622698
115GBX2_23144817_ChIP-Seq_PC3_Human1.03356814
116P68_20966046_ChIP-Seq_HELA_Human1.02981119
117JARID2_20064375_ChIP-Seq_MESCs_Mouse1.02832039
118CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01470949
119CREB1_15753290_ChIP-ChIP_HEK293T_Human1.00857075
120NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00300040
121NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00300040
122ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.00039963
123OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98682993
124AR_21909140_ChIP-Seq_LNCAP_Human0.98080710
125SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.97303377
126PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96895979
127SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.96510434
128* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95960983
129SOX2_20726797_ChIP-Seq_SW620_Human0.95510316
130CTCF_20526341_ChIP-Seq_ESCs_Human0.95271988
131ESR1_21235772_ChIP-Seq_MCF-7_Human0.94944742
132RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.94668866
133CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.94073949
134TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92719872
135E2F1_18555785_ChIP-Seq_MESCs_Mouse0.92658816
136ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92061358
137REST_18959480_ChIP-ChIP_MESCs_Mouse0.91346251
138* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91271663
139AR_20517297_ChIP-Seq_VCAP_Human0.85995221
140RNF2_27304074_Chip-Seq_ESCs_Mouse0.84385734
141* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81266060
142LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.81252760
143RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.80553119
144HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80317129
145HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79912228
146CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78870386
147SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77356606
148MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.76816539
149TET1_21451524_ChIP-Seq_MESCs_Mouse0.76218236
150MYC_18358816_ChIP-ChIP_MESCs_Mouse0.75771583
151ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.75766837
152TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.74805883
153EOMES_21245162_ChIP-Seq_HESCs_Human0.73092720
154CTBP1_25329375_ChIP-Seq_LNCAP_Human0.73031335
155SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.72094066

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.11573805
2MP0005503_abnormal_tendon_morphology4.79899886
3MP0009840_abnormal_foam_cell3.36017882
4MP0003122_maternal_imprinting3.33629995
5MP0005275_abnormal_skin_tensile3.10867373
6MP0006054_spinal_hemorrhage3.08161644
7MP0010386_abnormal_urinary_bladder2.54888506
8MP0005257_abnormal_intraocular_pressure2.52828342
9MP0000566_synostosis2.47552743
10MP0004272_abnormal_basement_membrane2.32975453
11MP0003191_abnormal_cellular_cholesterol2.15585583
12MP0005058_abnormal_lysosome_morphology2.07832153
13MP0001958_emphysema2.03097770
14MP0000372_irregular_coat_pigmentation1.96127115
15MP0002876_abnormal_thyroid_physiology1.83690232
16MP0003279_aneurysm1.83094224
17MP0008875_abnormal_xenobiotic_pharmacok1.82529942
18MP0000013_abnormal_adipose_tissue1.81212084
19MP0001529_abnormal_vocalization1.79085318
20MP0009384_cardiac_valve_regurgitation1.73474318
21MP0010234_abnormal_vibrissa_follicle1.73247599
22MP0001664_abnormal_digestion1.70770763
23MP0003136_yellow_coat_color1.68760815
24MP0002638_abnormal_pupillary_reflex1.63453512
25MP0005360_urolithiasis1.62574076
26MP0000538_abnormal_urinary_bladder1.59466657
27MP0005508_abnormal_skeleton_morphology1.58802967
28MP0005646_abnormal_pituitary_gland1.57672711
29MP0005220_abnormal_exocrine_pancreas1.53233830
30MP0002295_abnormal_pulmonary_circulatio1.51863569
31MP0001849_ear_inflammation1.51827973
32MP0002132_abnormal_respiratory_system1.49318685
33MP0005645_abnormal_hypothalamus_physiol1.48769768
34MP0003942_abnormal_urinary_system1.48317439
35MP0002653_abnormal_ependyma_morphology1.46874028
36MP0009379_abnormal_foot_pigmentation1.45959429
37MP0004264_abnormal_extraembryonic_tissu1.43556124
38MP0000681_abnormal_thyroid_gland1.43452869
39MP0002909_abnormal_adrenal_gland1.42417142
40MP0002938_white_spotting1.42191040
41MP0001756_abnormal_urination1.41466453
42MP0001542_abnormal_bone_strength1.40292904
43MP0006276_abnormal_autonomic_nervous1.40126044
44MP0003195_calcinosis1.38853795
45MP0001905_abnormal_dopamine_level1.38754479
46MP0002098_abnormal_vibrissa_morphology1.35874193
47MP0003183_abnormal_peptide_metabolism1.33912450
48MP0009780_abnormal_chondrocyte_physiolo1.33704780
49MP0003329_amyloid_beta_deposits1.31830213
50MP0001346_abnormal_lacrimal_gland1.29222885
51MP0005084_abnormal_gallbladder_morpholo1.27178984
52MP0000537_abnormal_urethra_morphology1.27051954
53MP0000049_abnormal_middle_ear1.26143757
54MP0008260_abnormal_autophagy1.25595103
55MP0002090_abnormal_vision1.24978722
56MP0003315_abnormal_perineum_morphology1.24862187
57MP0005636_abnormal_mineral_homeostasis1.22765577
58MP0002089_abnormal_postnatal_growth/wei1.22685858
59MP0005332_abnormal_amino_acid1.21026158
60MP0002108_abnormal_muscle_morphology1.20327349
61MP0008007_abnormal_cellular_replicative1.19011084
62MP0002736_abnormal_nociception_after1.15629998
63MP0004043_abnormal_pH_regulation1.15244182
64MP0003566_abnormal_cell_adhesion1.14698657
65MP0004858_abnormal_nervous_system1.13970905
66MP0001666_abnormal_nutrient_absorption1.11072645
67MP0000678_abnormal_parathyroid_gland1.07600156
68MP0010368_abnormal_lymphatic_system1.07471654
69MP0008004_abnormal_stomach_pH1.07035880
70MP0005501_abnormal_skin_physiology1.06826029
71MP0000467_abnormal_esophagus_morphology1.06717608
72MP0003941_abnormal_skin_development1.06351611
73MP0005451_abnormal_body_composition1.06112928
74MP0005595_abnormal_vascular_smooth1.05338467
75MP0000534_abnormal_ureter_morphology1.04529555
76MP0008932_abnormal_embryonic_tissue1.04477993
77MP0000358_abnormal_cell_content/1.04068429
78MP0003878_abnormal_ear_physiology1.03010395
79MP0005377_hearing/vestibular/ear_phenot1.03010395
80MP0003638_abnormal_response/metabolism_1.02681134
81MP0001299_abnormal_eye_distance/1.00305670
82MP0002796_impaired_skin_barrier0.98909072
83MP0005171_absent_coat_pigmentation0.98230185
84MP0001243_abnormal_dermal_layer0.97902565
85MP0000516_abnormal_urinary_system0.97718293
86MP0005367_renal/urinary_system_phenotyp0.97718293
87MP0005083_abnormal_biliary_tract0.97202655
88MP0003959_abnormal_lean_body0.96798320
89MP0005379_endocrine/exocrine_gland_phen0.96792217
90MP0005023_abnormal_wound_healing0.96576460
91MP0003172_abnormal_lysosome_physiology0.96528309
92MP0001270_distended_abdomen0.96093149
93MP0005410_abnormal_fertilization0.95698493
94MP0005408_hypopigmentation0.95417034
95MP0003705_abnormal_hypodermis_morpholog0.95189914
96MP0009697_abnormal_copulation0.94567824
97MP0002282_abnormal_trachea_morphology0.93880798
98MP0004134_abnormal_chest_morphology0.93879093
99MP0000762_abnormal_tongue_morphology0.93209995
100MP0000631_abnormal_neuroendocrine_gland0.92892607
101MP0000462_abnormal_digestive_system0.91316311
102MP0005365_abnormal_bile_salt0.91079186
103MP0001881_abnormal_mammary_gland0.90387062
104MP0004142_abnormal_muscle_tone0.89946596
105MP0002877_abnormal_melanocyte_morpholog0.89885968
106MP0003011_delayed_dark_adaptation0.89653648
107MP0009643_abnormal_urine_homeostasis0.89125040
108MP0005623_abnormal_meninges_morphology0.88866467
109MP0005197_abnormal_uvea_morphology0.88065259
110MP0003186_abnormal_redox_activity0.87074617
111MP0000230_abnormal_systemic_arterial0.87002765
112MP0004957_abnormal_blastocyst_morpholog0.86755296
113MP0002233_abnormal_nose_morphology0.86276867
114MP0003786_premature_aging0.84900214
115MP0002697_abnormal_eye_size0.84809638
116MP0009053_abnormal_anal_canal0.84650271
117MP0000163_abnormal_cartilage_morphology0.83290754
118MP0004133_heterotaxia0.82821292
119MP0002822_catalepsy0.82796880
120MP0003385_abnormal_body_wall0.82529073
121MP0003634_abnormal_glial_cell0.80994073
122MP0004883_abnormal_blood_vessel0.80070931
123MP0002064_seizures0.79947427
124MP0001177_atelectasis0.79713995
125MP0000639_abnormal_adrenal_gland0.79444816
126MP0002092_abnormal_eye_morphology0.78931955
127MP0005390_skeleton_phenotype0.78917395
128MP0005164_abnormal_response_to0.78278138
129MP0003879_abnormal_hair_cell0.77945747
130MP0001216_abnormal_epidermal_layer0.77716411
131MP0002896_abnormal_bone_mineralization0.77108410
132MP0001764_abnormal_homeostasis0.76723965
133MP0004019_abnormal_vitamin_homeostasis0.76632547
134MP0002249_abnormal_larynx_morphology0.76436860
135MP0001502_abnormal_circadian_rhythm0.76188388
136MP0001879_abnormal_lymphatic_vessel0.75358225
137MP0002060_abnormal_skin_morphology0.75011889
138MP0000377_abnormal_hair_follicle0.74521041
139MP0010678_abnormal_skin_adnexa0.74208055
140MP0010771_integument_phenotype0.73860270
141MP0003693_abnormal_embryo_hatching0.72840145
142MP0002572_abnormal_emotion/affect_behav0.72693099
143MP0001944_abnormal_pancreas_morphology0.72301693
144MP0003718_maternal_effect0.71851397
145MP0002933_joint_inflammation0.71842083
146MP0002139_abnormal_hepatobiliary_system0.71302605
147MP0003806_abnormal_nucleotide_metabolis0.71286021
148MP0005248_abnormal_Harderian_gland0.71124695
149MP0005165_increased_susceptibility_to0.70749263
150MP0002734_abnormal_mechanical_nocicepti0.70507821
151MP0002075_abnormal_coat/hair_pigmentati0.70216078
152MP0001765_abnormal_ion_homeostasis0.70075226
153MP0004782_abnormal_surfactant_physiolog0.69695934
154MP0000371_diluted_coat_color0.69448361
155MP0003283_abnormal_digestive_organ0.69302016
156MP0006036_abnormal_mitochondrial_physio0.68680161
157MP0003115_abnormal_respiratory_system0.68678768
158MP0002932_abnormal_joint_morphology0.68652051
159MP0010030_abnormal_orbit_morphology0.68537027
160MP0000647_abnormal_sebaceous_gland0.68487546
161MP0005551_abnormal_eye_electrophysiolog0.68389906
162MP0000604_amyloidosis0.67530281
163MP0008789_abnormal_olfactory_epithelium0.66103629

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.79195004
2Acute necrotizing encephalopathy (HP:0006965)4.25608704
3Abnormal mitochondria in muscle tissue (HP:0008316)4.09688064
4Protrusio acetabuli (HP:0003179)3.77527122
5Abnormal respiratory motile cilium physiology (HP:0012261)3.75949145
6Acute encephalopathy (HP:0006846)3.71782812
7Short nail (HP:0001799)3.68312605
8Abnormal respiratory motile cilium morphology (HP:0005938)3.65336533
9Abnormal respiratory epithelium morphology (HP:0012253)3.65336533
10Mitochondrial inheritance (HP:0001427)3.65237645
11Rhinitis (HP:0012384)3.63401699
12Vertebral compression fractures (HP:0002953)3.53036129
13Abnormal ciliary motility (HP:0012262)3.42837566
14Abnormality of dentin (HP:0010299)3.42106665
15Progressive macrocephaly (HP:0004481)3.37346237
16Hand muscle atrophy (HP:0009130)3.22775692
17Vacuolated lymphocytes (HP:0001922)3.21536576
18Renal Fanconi syndrome (HP:0001994)3.20069717
19Hepatocellular necrosis (HP:0001404)3.16816636
20Dynein arm defect of respiratory motile cilia (HP:0012255)3.13229325
21Absent/shortened dynein arms (HP:0200106)3.13229325
22Increased CSF lactate (HP:0002490)2.99446947
23Hypothermia (HP:0002045)2.86199487
24Hepatic necrosis (HP:0002605)2.85033274
25Distal upper limb amyotrophy (HP:0007149)2.81380351
26Upper limb amyotrophy (HP:0009129)2.81380351
27Occipital encephalocele (HP:0002085)2.78301575
28Dysostosis multiplex (HP:0000943)2.75413599
29Cervical subluxation (HP:0003308)2.70400016
30Abnormality of renal resorption (HP:0011038)2.57388528
31Polyphagia (HP:0002591)2.56777410
32Beaking of vertebral bodies (HP:0004568)2.54884876
33Vascular tortuosity (HP:0004948)2.51682528
34Abnormality of the distal phalanges of the toes (HP:0010182)2.44933461
35Broad metatarsal (HP:0001783)2.44491030
36Broad distal phalanx of finger (HP:0009836)2.44398847
37Premature rupture of membranes (HP:0001788)2.42358086
38Neuroendocrine neoplasm (HP:0100634)2.37954804
39Biconcave vertebral bodies (HP:0004586)2.37628404
40Nephrogenic diabetes insipidus (HP:0009806)2.33378236
41Increased hepatocellular lipid droplets (HP:0006565)2.32744837
42Arterial tortuosity (HP:0005116)2.32107576
43Pheochromocytoma (HP:0002666)2.29183956
44Chronic bronchitis (HP:0004469)2.26689105
45Lipid accumulation in hepatocytes (HP:0006561)2.26473734
46Male infertility (HP:0003251)2.25157680
47Hypoplasia of the capital femoral epiphysis (HP:0003090)2.24042092
48Increased neuronal autofluorescent lipopigment (HP:0002074)2.20168868
49Abnormality of the anterior horn cell (HP:0006802)2.19256718
50Degeneration of anterior horn cells (HP:0002398)2.19256718
51Hypoplasia of the uterus (HP:0000013)2.18455182
52Respiratory failure (HP:0002878)2.16359016
53Flattened epiphyses (HP:0003071)2.14815707
54Medial flaring of the eyebrow (HP:0010747)2.14200445
55Nasal polyposis (HP:0100582)2.13989682
56Conjugated hyperbilirubinemia (HP:0002908)2.11905361
57Abnormality of liposaccharide metabolism (HP:0010968)2.09202557
58Abnormality of glycosphingolipid metabolism (HP:0004343)2.09202557
59Abnormality of glycolipid metabolism (HP:0010969)2.09202557
60Cerebral edema (HP:0002181)2.08989251
61Tubulointerstitial nephritis (HP:0001970)2.08920183
62Atelectasis (HP:0100750)2.07846974
63Poor suck (HP:0002033)2.07101299
64Increased intramyocellular lipid droplets (HP:0012240)2.06986912
65Type I transferrin isoform profile (HP:0003642)2.06843224
66Prolonged neonatal jaundice (HP:0006579)2.06100679
67Abnormality of urine glucose concentration (HP:0011016)2.06090094
68Glycosuria (HP:0003076)2.06090094
69Abnormal number of erythroid precursors (HP:0012131)2.05902903
70Increased cerebral lipofuscin (HP:0011813)2.05270671
71Abnormal protein glycosylation (HP:0012346)2.04343331
72Abnormal glycosylation (HP:0012345)2.04343331
73Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.04343331
74Abnormal protein N-linked glycosylation (HP:0012347)2.04343331
75Trismus (HP:0000211)2.02557886
76Exercise intolerance (HP:0003546)2.02543771
77Loss of speech (HP:0002371)2.02238584
78Absent epiphyses (HP:0010577)2.00450555
79Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.00450555
80Urinary glycosaminoglycan excretion (HP:0003541)2.00361753
81Mucopolysacchariduria (HP:0008155)2.00361753
82Lactic acidosis (HP:0003128)2.00018242
83Leukodystrophy (HP:0002415)1.97550596
84Narrow nasal bridge (HP:0000446)1.97440872
85Deep venous thrombosis (HP:0002625)1.97035711
86Abnormality of cells of the erythroid lineage (HP:0012130)1.96153310
87Congenital primary aphakia (HP:0007707)1.95140602
88Hypokalemic alkalosis (HP:0001949)1.94794100
89Aplasia/hypoplasia of the uterus (HP:0008684)1.94620440
90Renal tubular dysfunction (HP:0000124)1.94404862
91J-shaped sella turcica (HP:0002680)1.93578624
92Gait imbalance (HP:0002141)1.93233499
93Hyperactive renin-angiotensin system (HP:0000841)1.93138996
94Testicular atrophy (HP:0000029)1.92477268
95Bell-shaped thorax (HP:0001591)1.92177115
96Nuclear cataract (HP:0100018)1.91981095
97Soft skin (HP:0000977)1.91130990
98Epiphyseal stippling (HP:0010655)1.90732407
99Renal salt wasting (HP:0000127)1.90289067
100Methylmalonic aciduria (HP:0012120)1.89417887
101Increased muscle lipid content (HP:0009058)1.88592882
102True hermaphroditism (HP:0010459)1.88009998
103Abnormal delivery (HP:0001787)1.87411748
104Rough bone trabeculation (HP:0100670)1.85163500
105Hypoventilation (HP:0002791)1.84592018
106Opisthotonus (HP:0002179)1.84236073
107Abnormality of the nasal mucosa (HP:0000433)1.83483516
108Abnormality of aromatic amino acid family metabolism (HP:0004338)1.83291016
109Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.83047983
110Hyperphosphaturia (HP:0003109)1.82906740
111Hyperaldosteronism (HP:0000859)1.81492741
112Abnormality of glycolysis (HP:0004366)1.81181919
113Increased serum pyruvate (HP:0003542)1.81181919
114Labial hypoplasia (HP:0000066)1.80728251
115Abnormality of mucopolysaccharide metabolism (HP:0011020)1.80102664
116Abnormality of polysaccharide metabolism (HP:0011012)1.80102664
117Abnormality of glycosaminoglycan metabolism (HP:0004371)1.80102664
118Abnormality of carpal bone ossification (HP:0006257)1.79925735
119Glucose intolerance (HP:0000833)1.78930142
120Oligomenorrhea (HP:0000876)1.78734152
121Cholecystitis (HP:0001082)1.77404678
122Abnormal gallbladder physiology (HP:0012438)1.77404678
123Optic disc pallor (HP:0000543)1.76726298
124Neoplasm of head and neck (HP:0012288)1.76307390
125Esophageal neoplasm (HP:0100751)1.76307390
126Neurofibrillary tangles (HP:0002185)1.75894881
127Progressive neurologic deterioration (HP:0002344)1.75769308
128Back pain (HP:0003418)1.75234520
129Systemic lupus erythematosus (HP:0002725)1.74948712
130Decreased circulating renin level (HP:0003351)1.74471100
131Congenital glaucoma (HP:0001087)1.73841717
132Reticulocytopenia (HP:0001896)1.73276996
133Pancreatic fibrosis (HP:0100732)1.72743459
134Primary adrenal insufficiency (HP:0008207)1.71193184
135CNS demyelination (HP:0007305)1.70923115
136Decreased activity of mitochondrial respiratory chain (HP:0008972)1.70748561
137Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.70748561
138Bronchiectasis (HP:0002110)1.70730339
139Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.70727240
140Vertebral hypoplasia (HP:0008417)1.70727240
1413-Methylglutaconic aciduria (HP:0003535)1.69962325
142Sparse eyelashes (HP:0000653)1.68621392
143Abnormality of the umbilical cord (HP:0010881)1.68593124
144Hypokinesia (HP:0002375)1.68078126
145Pterygium (HP:0001059)1.67880661
146Abnormality of the acetabulum (HP:0003170)1.67104125
147Cerebral palsy (HP:0100021)1.66977106
148Spastic paraparesis (HP:0002313)1.66734570
149Joint stiffness (HP:0001387)1.66314852
150Craniofacial dystonia (HP:0012179)1.66165070
151Gout (HP:0001997)1.66018881
152Facial cleft (HP:0002006)1.65564231
153Ketoacidosis (HP:0001993)1.64755584
154Wormian bones (HP:0002645)1.64551720
155Hypoplastic female external genitalia (HP:0012815)1.63719045
156Abnormal hair whorl (HP:0010721)1.63085909
157Follicular hyperkeratosis (HP:0007502)1.60289599
158Down-sloping shoulders (HP:0200021)1.59934562
159Abnormalities of placenta or umbilical cord (HP:0001194)1.59215250
160Abnormality of the Achilles tendon (HP:0005109)1.58422749
161Vascular calcification (HP:0004934)1.57704057
162Abnormality of monocarboxylic acid metabolism (HP:0010996)1.57274889
163Spinal cord compression (HP:0002176)1.56757655
164Microglossia (HP:0000171)1.56133455
165Infertility (HP:0000789)1.51698987
166Abnormal trabecular bone morphology (HP:0100671)1.51338837

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.53362705
2MAP3K123.36160298
3MYLK3.20695934
4CASK2.94440629
5ERN12.89693872
6BCKDK2.86370105
7PIM22.85103601
8ARAF2.69945992
9STK162.61429745
10TRIB32.57421796
11TESK22.54537179
12IRAK32.17922254
13PBK2.11673169
14TESK11.97284582
15EPHB21.95608251
16MAPK151.93773206
17WNK31.90088052
18NME11.87974374
19TSSK61.86432122
20AKT31.85413367
21LMTK21.80965894
22BRAF1.79967650
23CDK191.75755776
24SMG11.75685891
25WNK41.71689653
26ICK1.50976580
27BUB11.45389580
28SIK31.41961879
29PTK21.39986268
30MAPKAPK31.39846903
31BMPR1B1.38138631
32PLK21.34890714
33PIK3CG1.34369146
34MST1R1.33327197
35LIMK11.33021384
36EIF2AK11.30088531
37TGFBR21.28232060
38OXSR11.22220509
39NME21.20697175
40PKN21.19453984
41CDK81.19057612
42BRSK11.18445746
43SCYL21.17561137
44MAP2K71.15796649
45PAK41.15791452
46TGFBR11.14116833
47MUSK1.12106099
48EPHA31.11306113
49ADRBK21.10323107
50CDK71.08647045
51MAP3K31.08063988
52EPHA21.06902902
53DDR21.05784405
54ABL21.05073533
55ILK1.02190230
56FER1.00536363
57SIK10.99623018
58INSRR0.99573650
59PRKD30.98477950
60EEF2K0.96358762
61ERBB30.95914939
62NEK10.94273530
63RPS6KB20.94031572
64GRK70.93876118
65TIE10.93792667
66UHMK10.93524819
67KIT0.93190961
68NTRK20.92663437
69EPHB10.92655950
70DAPK30.91863625
71MAP2K20.91739371
72DAPK10.89344140
73PDGFRA0.85496588
74FGFR40.84388425
75PRKCE0.84250716
76NTRK10.83388571
77PTK60.82897549
78ADRBK10.82428182
79MAPK130.81530504
80EIF2AK30.81515868
81MAPKAPK50.81044038
82DYRK20.78948012
83BCR0.78459878
84TTK0.77964082
85SGK2230.77270417
86SGK4940.77270417
87FRK0.76251063
88PRKCI0.73750801
89MAP3K20.72960820
90WEE10.70164791
91CSNK1A1L0.70052852
92CAMK2G0.64108234
93TNK20.63385032
94AURKA0.62974983
95IRAK10.62224481
96CSNK1G10.61823727
97MARK10.60348768
98BRSK20.60275352
99PDK20.59928431
100SRPK10.58668158
101FLT30.58297934
102LRRK20.58051778
103CAMKK20.57035293
104PRKCG0.57020694
105DAPK20.55392863
106BMX0.55335453
107PASK0.54531385
108CCNB10.54300370
109MST40.53951628
110STK390.51831947
111PRKG20.51324721
112PDK30.50662823
113PDK40.50662823
114TRIM280.50352878
115MAP2K10.49212692
116IRAK20.48680326
117MET0.48184906
118PAK20.46903939
119ROCK20.46570541
120AURKB0.46492772
121ERBB40.45353528
122STK380.45289486
123CSNK1G30.44788127
124NTRK30.44747396
125PRPF4B0.43945683
126VRK10.43237003
127CAMK2B0.42157517
128RPS6KA20.41767085
129MAP3K60.41468027
130AKT20.41339893
131MAP2K60.40949764
132PLK10.39104661
133CDK180.38657132
134CDK140.37693326
135PRKD20.37667150
136ROCK10.37076421
137CSNK1G20.36930451
138TNIK0.36735468
139CHEK20.36585983
140MINK10.35806273
141DYRK1B0.34544790
142CDK90.34331878
143CSNK2A10.32500382
144GSK3A0.32347491
145NEK20.32227654
146CSNK2A20.31725854
147MTOR0.31323778
148MAP4K20.31291675
149TAOK20.30335021
150PAK10.30331075
151TBK10.26459562
152MAPKAPK20.23790211

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030604.47216048
2Oxidative phosphorylation_Homo sapiens_hsa001903.88129087
3Parkinsons disease_Homo sapiens_hsa050123.05030682
4Proteasome_Homo sapiens_hsa030502.91836936
5Vibrio cholerae infection_Homo sapiens_hsa051102.82986984
6Collecting duct acid secretion_Homo sapiens_hsa049662.73186759
7Alzheimers disease_Homo sapiens_hsa050102.26306973
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.22643786
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.14083544
10Sulfur metabolism_Homo sapiens_hsa009202.06877976
11Huntingtons disease_Homo sapiens_hsa050162.05270265
12Other glycan degradation_Homo sapiens_hsa005112.02731198
13N-Glycan biosynthesis_Homo sapiens_hsa005102.01161277
14Fatty acid elongation_Homo sapiens_hsa000621.96836435
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.78497795
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.77279205
17Synaptic vesicle cycle_Homo sapiens_hsa047211.74030486
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71356838
19Lysosome_Homo sapiens_hsa041421.64525584
20Ribosome_Homo sapiens_hsa030101.63210326
21Pyruvate metabolism_Homo sapiens_hsa006201.59393969
22Base excision repair_Homo sapiens_hsa034101.50999302
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.49555062
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.49394544
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.41055056
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.37106442
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.33583780
28Phagosome_Homo sapiens_hsa041451.30564498
29Butanoate metabolism_Homo sapiens_hsa006501.28794036
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.24885749
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.23545751
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.22372313
33Glycosaminoglycan degradation_Homo sapiens_hsa005311.20000913
34Pyrimidine metabolism_Homo sapiens_hsa002401.19506581
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17968904
36Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17711105
37Propanoate metabolism_Homo sapiens_hsa006401.14610078
38DNA replication_Homo sapiens_hsa030301.13405065
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10698255
40Sulfur relay system_Homo sapiens_hsa041221.08835046
41Fatty acid metabolism_Homo sapiens_hsa012121.07416661
42SNARE interactions in vesicular transport_Homo sapiens_hsa041301.06998904
43Nucleotide excision repair_Homo sapiens_hsa034201.05438906
44Rheumatoid arthritis_Homo sapiens_hsa053231.05432247
45Glutathione metabolism_Homo sapiens_hsa004801.05416534
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02134767
47Histidine metabolism_Homo sapiens_hsa003401.01013363
48Mismatch repair_Homo sapiens_hsa034301.00808635
49Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.99221063
50Galactose metabolism_Homo sapiens_hsa000520.96860564
51Steroid biosynthesis_Homo sapiens_hsa001000.95202004
52Peroxisome_Homo sapiens_hsa041460.94563651
53Fatty acid degradation_Homo sapiens_hsa000710.93645815
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.93544872
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.92282499
56Complement and coagulation cascades_Homo sapiens_hsa046100.92212242
57Vitamin digestion and absorption_Homo sapiens_hsa049770.91419570
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91381317
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90919651
60Fructose and mannose metabolism_Homo sapiens_hsa000510.88427299
61Protein digestion and absorption_Homo sapiens_hsa049740.88205838
62Regulation of autophagy_Homo sapiens_hsa041400.86473471
63Carbon metabolism_Homo sapiens_hsa012000.86095941
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.85066798
65Arachidonic acid metabolism_Homo sapiens_hsa005900.84300759
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83995816
67Metabolic pathways_Homo sapiens_hsa011000.83943188
68Folate biosynthesis_Homo sapiens_hsa007900.83766268
69Tyrosine metabolism_Homo sapiens_hsa003500.82410786
70Chemical carcinogenesis_Homo sapiens_hsa052040.82103985
71Renin-angiotensin system_Homo sapiens_hsa046140.78774586
72Phenylalanine metabolism_Homo sapiens_hsa003600.78488282
73Arginine biosynthesis_Homo sapiens_hsa002200.78424939
74Fat digestion and absorption_Homo sapiens_hsa049750.75493638
75Arginine and proline metabolism_Homo sapiens_hsa003300.75127126
76GABAergic synapse_Homo sapiens_hsa047270.73468066
77Cardiac muscle contraction_Homo sapiens_hsa042600.71858312
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71281444
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.67380661
80Sphingolipid metabolism_Homo sapiens_hsa006000.66923266
81Vitamin B6 metabolism_Homo sapiens_hsa007500.66109107
82Spliceosome_Homo sapiens_hsa030400.64613106
83Cocaine addiction_Homo sapiens_hsa050300.62802179
84Nicotine addiction_Homo sapiens_hsa050330.62799998
85Prion diseases_Homo sapiens_hsa050200.60554956
86Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.60524088
87RNA transport_Homo sapiens_hsa030130.60433324
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60040441
89Biosynthesis of amino acids_Homo sapiens_hsa012300.59202391
90beta-Alanine metabolism_Homo sapiens_hsa004100.59067510
91Purine metabolism_Homo sapiens_hsa002300.58480652
92Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56113065
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.53536638
94Retinol metabolism_Homo sapiens_hsa008300.50263766
95Insulin secretion_Homo sapiens_hsa049110.50181586
96Thyroid hormone synthesis_Homo sapiens_hsa049180.49948756
97Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.49933679
98Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47133094
99ECM-receptor interaction_Homo sapiens_hsa045120.46813701
100Basal cell carcinoma_Homo sapiens_hsa052170.45994737
101Tryptophan metabolism_Homo sapiens_hsa003800.44102581
102Pentose phosphate pathway_Homo sapiens_hsa000300.44089838
103Bladder cancer_Homo sapiens_hsa052190.43012974
104PPAR signaling pathway_Homo sapiens_hsa033200.42755515
105Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40949382
106RNA polymerase_Homo sapiens_hsa030200.39948314
107Cysteine and methionine metabolism_Homo sapiens_hsa002700.39437764
108Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.39365354
109Non-homologous end-joining_Homo sapiens_hsa034500.37813801
110Mineral absorption_Homo sapiens_hsa049780.37391120
111Drug metabolism - other enzymes_Homo sapiens_hsa009830.36192689
112Starch and sucrose metabolism_Homo sapiens_hsa005000.35110389
113Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.34753378
114Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33640518
115Homologous recombination_Homo sapiens_hsa034400.33373467
116Tight junction_Homo sapiens_hsa045300.33026639
117Serotonergic synapse_Homo sapiens_hsa047260.31895614
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31570565
119Pancreatic secretion_Homo sapiens_hsa049720.31513833
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.31356891
121Taste transduction_Homo sapiens_hsa047420.30110764
122Hedgehog signaling pathway_Homo sapiens_hsa043400.29916142
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.29870167
124Steroid hormone biosynthesis_Homo sapiens_hsa001400.29388585

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