

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sequestering of actin monomers (GO:0042989) | 8.21314754 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.25785010 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.33611883 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.71748283 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.71748283 |
| 6 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.33760383 |
| 7 | DNA deamination (GO:0045006) | 5.14300206 |
| 8 | proteasome assembly (GO:0043248) | 5.01117985 |
| 9 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.91579164 |
| 10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.79940831 |
| 11 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.75701185 |
| 12 | actin nucleation (GO:0045010) | 4.68843620 |
| 13 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.66473470 |
| 14 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.66473470 |
| 15 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.66473470 |
| 16 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.62315744 |
| 17 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.62315744 |
| 18 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.59435354 |
| 19 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.56339499 |
| 20 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.56339499 |
| 21 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.52351841 |
| 22 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.46471195 |
| 23 | respiratory electron transport chain (GO:0022904) | 4.45417193 |
| 24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.34520425 |
| 25 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.33604738 |
| 26 | negative regulation of ligase activity (GO:0051352) | 4.33604738 |
| 27 | electron transport chain (GO:0022900) | 4.33194462 |
| 28 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.27345357 |
| 29 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.12688366 |
| 30 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 4.03743664 |
| 31 | negative regulation by host of viral transcription (GO:0043922) | 3.97678487 |
| 32 | cytidine metabolic process (GO:0046087) | 3.86734544 |
| 33 | cytidine catabolic process (GO:0006216) | 3.86734544 |
| 34 | cytidine deamination (GO:0009972) | 3.86734544 |
| 35 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.73219546 |
| 36 | positive regulation of ligase activity (GO:0051351) | 3.69890298 |
| 37 | DNA ligation (GO:0006266) | 3.63930704 |
| 38 | 7-methylguanosine mRNA capping (GO:0006370) | 3.62583908 |
| 39 | positive regulation of cell cycle arrest (GO:0071158) | 3.61193927 |
| 40 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.56673005 |
| 41 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.54280351 |
| 42 | cytolysis (GO:0019835) | 3.53015440 |
| 43 | 7-methylguanosine RNA capping (GO:0009452) | 3.52866549 |
| 44 | RNA capping (GO:0036260) | 3.52866549 |
| 45 | regulation of cellular amine metabolic process (GO:0033238) | 3.52068806 |
| 46 | protein neddylation (GO:0045116) | 3.51238319 |
| 47 | rRNA modification (GO:0000154) | 3.44909442 |
| 48 | inositol phosphate dephosphorylation (GO:0046855) | 3.44600151 |
| 49 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.44600151 |
| 50 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.41531256 |
| 51 | gonadal mesoderm development (GO:0007506) | 3.40973219 |
| 52 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.34927607 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.31515703 |
| 54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.31515703 |
| 55 | hydrogen ion transmembrane transport (GO:1902600) | 3.25443894 |
| 56 | chaperone-mediated protein transport (GO:0072321) | 3.25340828 |
| 57 | platelet dense granule organization (GO:0060155) | 3.25222152 |
| 58 | protein complex biogenesis (GO:0070271) | 3.24387259 |
| 59 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.19561730 |
| 60 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.18877722 |
| 61 | regulation of ligase activity (GO:0051340) | 3.18585643 |
| 62 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.15357381 |
| 63 | termination of RNA polymerase III transcription (GO:0006386) | 3.15357381 |
| 64 | negative regulation of stress fiber assembly (GO:0051497) | 3.15355334 |
| 65 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 3.14197598 |
| 66 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 3.14197598 |
| 67 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.13041814 |
| 68 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.12070370 |
| 69 | apoptotic DNA fragmentation (GO:0006309) | 3.05196570 |
| 70 | regulation of cell cycle arrest (GO:0071156) | 3.00101722 |
| 71 | proton transport (GO:0015992) | 2.99454062 |
| 72 | ubiquinone biosynthetic process (GO:0006744) | 2.97460845 |
| 73 | viral mRNA export from host cell nucleus (GO:0046784) | 2.96716010 |
| 74 | hydrogen transport (GO:0006818) | 2.95564068 |
| 75 | signal transduction in response to DNA damage (GO:0042770) | 2.95021384 |
| 76 | inositol phosphate catabolic process (GO:0071545) | 2.94785570 |
| 77 | GDP-mannose metabolic process (GO:0019673) | 2.94266259 |
| 78 | negative regulation of protein ubiquitination (GO:0031397) | 2.94066940 |
| 79 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.92488476 |
| 80 | positive regulation of actin filament depolymerization (GO:0030836) | 2.92447760 |
| 81 | ATP biosynthetic process (GO:0006754) | 2.88632694 |
| 82 | cullin deneddylation (GO:0010388) | 2.88476605 |
| 83 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.83187638 |
| 84 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.81984161 |
| 85 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.81984161 |
| 86 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.81960626 |
| 87 | negative regulation of protein modification by small protein conjugation or removal (GO:1903321) | 2.80169934 |
| 88 | base-excision repair, AP site formation (GO:0006285) | 2.79609814 |
| 89 | rRNA methylation (GO:0031167) | 2.76729986 |
| 90 | ubiquinone metabolic process (GO:0006743) | 2.76531743 |
| 91 | GPI anchor biosynthetic process (GO:0006506) | 2.74251655 |
| 92 | spermatid nucleus differentiation (GO:0007289) | 2.71958733 |
| 93 | CENP-A containing nucleosome assembly (GO:0034080) | 2.71202356 |
| 94 | GPI anchor metabolic process (GO:0006505) | 2.69522801 |
| 95 | histone mRNA metabolic process (GO:0008334) | 2.68845339 |
| 96 | GTP biosynthetic process (GO:0006183) | 2.65944963 |
| 97 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.64085675 |
| 98 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.64085675 |
| 99 | NADH dehydrogenase complex assembly (GO:0010257) | 2.64085675 |
| 100 | adenosine metabolic process (GO:0046085) | 2.62936679 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.71450263 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.31715820 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.46100891 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.39156843 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.26758580 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.13718522 |
| 7 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.06834726 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.94733733 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.87393116 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.84723483 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.79577405 |
| 12 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.78808350 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.70486907 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.70117987 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62222779 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.57341398 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.44131752 |
| 18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.34214403 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22744425 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.21495425 |
| 21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.16275676 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.14386129 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.10564039 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.05599571 |
| 25 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.01995797 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.99574291 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.98002351 |
| 28 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.96988895 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.83932072 |
| 30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.79961861 |
| 31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.79591840 |
| 32 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.79487017 |
| 33 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.70634265 |
| 34 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.66452153 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.66242518 |
| 36 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.63730429 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.60395784 |
| 38 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.58621481 |
| 39 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.57341179 |
| 40 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.54982222 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54844519 |
| 42 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.52640762 |
| 43 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.51497443 |
| 44 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.48391300 |
| 45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.40277508 |
| 46 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.38650039 |
| 47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.38469145 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.36598976 |
| 49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33245735 |
| 50 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.32647385 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.30155853 |
| 52 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.27653705 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26656969 |
| 54 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26355917 |
| 55 | MYB_26560356_Chip-Seq_TH2_Human | 1.25724353 |
| 56 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.25603474 |
| 57 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.24376373 |
| 58 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.23516024 |
| 59 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.22523958 |
| 60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.22488734 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.21879090 |
| 62 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.21395330 |
| 63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.18893762 |
| 64 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.17168238 |
| 65 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16243569 |
| 66 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15845505 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.15399196 |
| 68 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.14493428 |
| 69 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13716597 |
| 70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.13183855 |
| 71 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.13086605 |
| 72 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09186249 |
| 73 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08351598 |
| 74 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08351598 |
| 75 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.08280676 |
| 76 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08093079 |
| 77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.06748564 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06332114 |
| 79 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.03836029 |
| 80 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03505345 |
| 81 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.02056462 |
| 82 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.01076167 |
| 83 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99557667 |
| 84 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.97442949 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95867114 |
| 86 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.95669678 |
| 87 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95139287 |
| 88 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.94508625 |
| 89 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.94095639 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93238406 |
| 91 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92248958 |
| 92 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.92211883 |
| 93 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.91724493 |
| 94 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91395464 |
| 95 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89794594 |
| 96 | AR_20517297_ChIP-Seq_VCAP_Human | 0.88499273 |
| 97 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88251293 |
| 98 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.86410434 |
| 99 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86233283 |
| 100 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.84542551 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.37732227 |
| 2 | MP0002102_abnormal_ear_morphology | 3.13570762 |
| 3 | MP0003646_muscle_fatigue | 3.02619138 |
| 4 | MP0002166_altered_tumor_susceptibility | 2.89719247 |
| 5 | MP0005084_abnormal_gallbladder_morpholo | 2.85435868 |
| 6 | MP0009697_abnormal_copulation | 2.82566508 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.76684481 |
| 8 | MP0004147_increased_porphyrin_level | 2.76107725 |
| 9 | MP0004957_abnormal_blastocyst_morpholog | 2.61922253 |
| 10 | MP0002006_tumorigenesis | 2.34767962 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.34505313 |
| 12 | MP0008058_abnormal_DNA_repair | 2.22970896 |
| 13 | MP0005167_abnormal_blood-brain_barrier | 2.22614521 |
| 14 | MP0002837_dystrophic_cardiac_calcinosis | 2.05345963 |
| 15 | MP0002234_abnormal_pharynx_morphology | 2.04944325 |
| 16 | MP0003786_premature_aging | 2.02938407 |
| 17 | MP0009785_altered_susceptibility_to | 1.99660056 |
| 18 | MP0001919_abnormal_reproductive_system | 1.97726880 |
| 19 | MP0003693_abnormal_embryo_hatching | 1.97642413 |
| 20 | MP0003724_increased_susceptibility_to | 1.96536855 |
| 21 | MP0003763_abnormal_thymus_physiology | 1.74977785 |
| 22 | MP0001879_abnormal_lymphatic_vessel | 1.66657232 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 1.66550705 |
| 24 | MP0010094_abnormal_chromosome_stability | 1.63539333 |
| 25 | MP0003806_abnormal_nucleotide_metabolis | 1.56784602 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.54539182 |
| 27 | MP0005377_hearing/vestibular/ear_phenot | 1.51932677 |
| 28 | MP0003878_abnormal_ear_physiology | 1.51932677 |
| 29 | MP0005000_abnormal_immune_tolerance | 1.45842531 |
| 30 | MP0005389_reproductive_system_phenotype | 1.43989005 |
| 31 | MP0005253_abnormal_eye_physiology | 1.42891840 |
| 32 | MP0003195_calcinosis | 1.37412887 |
| 33 | MP0006054_spinal_hemorrhage | 1.35777848 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.33379189 |
| 35 | MP0002420_abnormal_adaptive_immunity | 1.33323478 |
| 36 | MP0001727_abnormal_embryo_implantation | 1.33237452 |
| 37 | MP0001819_abnormal_immune_cell | 1.32819357 |
| 38 | MP0001800_abnormal_humoral_immune | 1.30339970 |
| 39 | MP0003866_abnormal_defecation | 1.29536443 |
| 40 | MP0003011_delayed_dark_adaptation | 1.29466052 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.28546247 |
| 42 | MP0001835_abnormal_antigen_presentation | 1.26193157 |
| 43 | MP0002723_abnormal_immune_serum | 1.25884141 |
| 44 | MP0002090_abnormal_vision | 1.21715566 |
| 45 | MP0006036_abnormal_mitochondrial_physio | 1.18892145 |
| 46 | MP0006276_abnormal_autonomic_nervous | 1.18526017 |
| 47 | MP0008932_abnormal_embryonic_tissue | 1.15373350 |
| 48 | MP0003880_abnormal_central_pattern | 1.14841800 |
| 49 | MP0001661_extended_life_span | 1.14782936 |
| 50 | MP0002160_abnormal_reproductive_system | 1.14207254 |
| 51 | MP0002277_abnormal_respiratory_mucosa | 1.13534348 |
| 52 | MP0001293_anophthalmia | 1.13383811 |
| 53 | MP0005646_abnormal_pituitary_gland | 1.12236599 |
| 54 | MP0002938_white_spotting | 1.11113003 |
| 55 | MP0002876_abnormal_thyroid_physiology | 1.09096952 |
| 56 | MP0002452_abnormal_antigen_presenting | 1.08177951 |
| 57 | MP0005551_abnormal_eye_electrophysiolog | 1.08081549 |
| 58 | MP0006292_abnormal_olfactory_placode | 1.03693401 |
| 59 | MP0005025_abnormal_response_to | 1.01293366 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 0.98160509 |
| 61 | MP0003567_abnormal_fetal_cardiomyocyte | 0.97700987 |
| 62 | MP0004084_abnormal_cardiac_muscle | 0.96202554 |
| 63 | MP0004215_abnormal_myocardial_fiber | 0.95191181 |
| 64 | MP0002693_abnormal_pancreas_physiology | 0.94381512 |
| 65 | MP0004036_abnormal_muscle_relaxation | 0.92700309 |
| 66 | MP0008007_abnormal_cellular_replicative | 0.87479055 |
| 67 | MP0002398_abnormal_bone_marrow | 0.87460277 |
| 68 | MP0001845_abnormal_inflammatory_respons | 0.86194293 |
| 69 | MP0002210_abnormal_sex_determination | 0.85727086 |
| 70 | MP0006035_abnormal_mitochondrial_morpho | 0.83250991 |
| 71 | MP0008775_abnormal_heart_ventricle | 0.82961180 |
| 72 | MP0002928_abnormal_bile_duct | 0.82338561 |
| 73 | MP0000689_abnormal_spleen_morphology | 0.81160978 |
| 74 | MP0003718_maternal_effect | 0.79567258 |
| 75 | MP0000716_abnormal_immune_system | 0.78444410 |
| 76 | MP0002405_respiratory_system_inflammati | 0.77094911 |
| 77 | MP0001929_abnormal_gametogenesis | 0.76703994 |
| 78 | MP0009046_muscle_twitch | 0.75388943 |
| 79 | MP0001790_abnormal_immune_system | 0.73637414 |
| 80 | MP0005387_immune_system_phenotype | 0.73637414 |
| 81 | MP0009764_decreased_sensitivity_to | 0.73366785 |
| 82 | MP0000685_abnormal_immune_system | 0.73357014 |
| 83 | MP0002933_joint_inflammation | 0.73313058 |
| 84 | MP0003137_abnormal_impulse_conducting | 0.72623457 |
| 85 | MP0003111_abnormal_nucleus_morphology | 0.71586281 |
| 86 | MP0001485_abnormal_pinna_reflex | 0.71052178 |
| 87 | MP0001145_abnormal_male_reproductive | 0.70793807 |
| 88 | MP0008875_abnormal_xenobiotic_pharmacok | 0.70695929 |
| 89 | MP0008872_abnormal_physiological_respon | 0.69679040 |
| 90 | MP0003448_altered_tumor_morphology | 0.68714813 |
| 91 | MP0001119_abnormal_female_reproductive | 0.67755179 |
| 92 | MP0002429_abnormal_blood_cell | 0.67617970 |
| 93 | MP0000653_abnormal_sex_gland | 0.67140479 |
| 94 | MP0001544_abnormal_cardiovascular_syste | 0.66042604 |
| 95 | MP0005385_cardiovascular_system_phenoty | 0.66042604 |
| 96 | MP0002722_abnormal_immune_system | 0.65284460 |
| 97 | MP0000703_abnormal_thymus_morphology | 0.65144577 |
| 98 | MP0001986_abnormal_taste_sensitivity | 0.63723940 |
| 99 | MP0002272_abnormal_nervous_system | 0.62407194 |
| 100 | MP0002148_abnormal_hypersensitivity_rea | 0.62344033 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.89471278 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.67502100 |
| 3 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.60495680 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 4.17843684 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.16946423 |
| 6 | Renal Fanconi syndrome (HP:0001994) | 4.04519149 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.88466336 |
| 8 | Increased intramyocellular lipid droplets (HP:0012240) | 3.83722783 |
| 9 | IgG deficiency (HP:0004315) | 3.81602101 |
| 10 | Hepatic necrosis (HP:0002605) | 3.79686997 |
| 11 | IgM deficiency (HP:0002850) | 3.71136813 |
| 12 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.59389958 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.56882369 |
| 14 | Increased CSF lactate (HP:0002490) | 3.53900022 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.52527038 |
| 16 | Exertional dyspnea (HP:0002875) | 3.38649727 |
| 17 | Type I transferrin isoform profile (HP:0003642) | 3.37155637 |
| 18 | Colon cancer (HP:0003003) | 3.26788973 |
| 19 | Stomach cancer (HP:0012126) | 3.26297042 |
| 20 | Acute encephalopathy (HP:0006846) | 3.23168515 |
| 21 | Prostate neoplasm (HP:0100787) | 3.15229265 |
| 22 | Increased muscle lipid content (HP:0009058) | 2.96322320 |
| 23 | Aplastic anemia (HP:0001915) | 2.92107459 |
| 24 | Abnormality of midbrain morphology (HP:0002418) | 2.91645687 |
| 25 | Molar tooth sign on MRI (HP:0002419) | 2.91645687 |
| 26 | Generalized aminoaciduria (HP:0002909) | 2.86914022 |
| 27 | Increased serum lactate (HP:0002151) | 2.85466305 |
| 28 | Exercise intolerance (HP:0003546) | 2.78739853 |
| 29 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.78517469 |
| 30 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.78517469 |
| 31 | Cerebral edema (HP:0002181) | 2.74906135 |
| 32 | Increased IgM level (HP:0003496) | 2.71499620 |
| 33 | Reduced antithrombin III activity (HP:0001976) | 2.70685302 |
| 34 | Abnormality of urine glucose concentration (HP:0011016) | 2.68545315 |
| 35 | Glycosuria (HP:0003076) | 2.68545315 |
| 36 | Abnormality of the prostate (HP:0008775) | 2.64203671 |
| 37 | T lymphocytopenia (HP:0005403) | 2.60307673 |
| 38 | 3-Methylglutaconic aciduria (HP:0003535) | 2.57509875 |
| 39 | Oral leukoplakia (HP:0002745) | 2.50931277 |
| 40 | Abnormality of T cell number (HP:0011839) | 2.50704257 |
| 41 | Pancytopenia (HP:0001876) | 2.50504556 |
| 42 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.43447969 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.42556830 |
| 44 | Hypomagnesemia (HP:0002917) | 2.40200694 |
| 45 | Progressive muscle weakness (HP:0003323) | 2.39708849 |
| 46 | Abnormality of renal resorption (HP:0011038) | 2.38983191 |
| 47 | Tetany (HP:0001281) | 2.37457736 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.37156096 |
| 49 | Cellular immunodeficiency (HP:0005374) | 2.33223377 |
| 50 | Lactic acidosis (HP:0003128) | 2.32253821 |
| 51 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.29906793 |
| 52 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.29906793 |
| 53 | Abnormal protein glycosylation (HP:0012346) | 2.29906793 |
| 54 | Abnormal glycosylation (HP:0012345) | 2.29906793 |
| 55 | Amyotrophic lateral sclerosis (HP:0007354) | 2.23576527 |
| 56 | Chronic diarrhea (HP:0002028) | 2.23358574 |
| 57 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.22187706 |
| 58 | Pancreatic cysts (HP:0001737) | 2.21578442 |
| 59 | Optic disc pallor (HP:0000543) | 2.21360663 |
| 60 | Severe combined immunodeficiency (HP:0004430) | 2.19942310 |
| 61 | Respiratory failure (HP:0002878) | 2.18762460 |
| 62 | Renal cortical cysts (HP:0000803) | 2.15921938 |
| 63 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.14783238 |
| 64 | Chronic hepatic failure (HP:0100626) | 2.12509999 |
| 65 | True hermaphroditism (HP:0010459) | 2.11883217 |
| 66 | Respiratory difficulties (HP:0002880) | 2.09962328 |
| 67 | Birth length less than 3rd percentile (HP:0003561) | 2.09251022 |
| 68 | Increased circulating renin level (HP:0000848) | 2.06764014 |
| 69 | Hypoalbuminemia (HP:0003073) | 2.05328032 |
| 70 | Abnormal albumin level (HP:0012116) | 2.05328032 |
| 71 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.04956917 |
| 72 | Hyperphosphaturia (HP:0003109) | 2.03015734 |
| 73 | Abnormality of T cells (HP:0002843) | 2.01195194 |
| 74 | Hypoglycemic coma (HP:0001325) | 1.99207007 |
| 75 | Combined immunodeficiency (HP:0005387) | 1.98367865 |
| 76 | Agitation (HP:0000713) | 1.95270750 |
| 77 | Emotional lability (HP:0000712) | 1.92482938 |
| 78 | Pendular nystagmus (HP:0012043) | 1.91344518 |
| 79 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.91074640 |
| 80 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.90148867 |
| 81 | Hypoproteinemia (HP:0003075) | 1.89359101 |
| 82 | Medial flaring of the eyebrow (HP:0010747) | 1.85134612 |
| 83 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.83173221 |
| 84 | Dicarboxylic aciduria (HP:0003215) | 1.83173221 |
| 85 | Sclerocornea (HP:0000647) | 1.81815004 |
| 86 | Congenital primary aphakia (HP:0007707) | 1.81676112 |
| 87 | Nausea (HP:0002018) | 1.80319520 |
| 88 | Reticulocytopenia (HP:0001896) | 1.80024625 |
| 89 | Gait imbalance (HP:0002141) | 1.74807058 |
| 90 | Hypothermia (HP:0002045) | 1.74587405 |
| 91 | Abnormality of the renal cortex (HP:0011035) | 1.74329324 |
| 92 | Abnormality of magnesium homeostasis (HP:0004921) | 1.73777582 |
| 93 | Sensory axonal neuropathy (HP:0003390) | 1.72713156 |
| 94 | Female pseudohermaphroditism (HP:0010458) | 1.72136913 |
| 95 | Abnormality of the anterior horn cell (HP:0006802) | 1.71052699 |
| 96 | Degeneration of anterior horn cells (HP:0002398) | 1.71052699 |
| 97 | Testicular atrophy (HP:0000029) | 1.69992248 |
| 98 | Hypoplasia of the uterus (HP:0000013) | 1.69871690 |
| 99 | Constricted visual fields (HP:0001133) | 1.69102949 |
| 100 | Congenital stationary night blindness (HP:0007642) | 1.68919369 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 4.42645293 |
| 2 | KDR | 4.29885100 |
| 3 | TIE1 | 4.28042325 |
| 4 | BUB1 | 3.66117836 |
| 5 | VRK2 | 3.39310140 |
| 6 | MAP3K12 | 3.24160575 |
| 7 | LIMK1 | 3.08402968 |
| 8 | TXK | 2.94549642 |
| 9 | MST4 | 2.89575517 |
| 10 | ZAK | 2.88415533 |
| 11 | TESK1 | 2.80720785 |
| 12 | BCKDK | 2.75326537 |
| 13 | VRK1 | 2.53060027 |
| 14 | STK16 | 2.11338578 |
| 15 | TLK1 | 1.91405595 |
| 16 | DYRK3 | 1.82304965 |
| 17 | TAOK3 | 1.80508580 |
| 18 | GRK1 | 1.78714792 |
| 19 | TEC | 1.55728951 |
| 20 | PLK4 | 1.53079544 |
| 21 | BLK | 1.51494210 |
| 22 | NEK1 | 1.47687424 |
| 23 | ITK | 1.45839298 |
| 24 | RPS6KA4 | 1.44127214 |
| 25 | MAPKAPK3 | 1.31787973 |
| 26 | ADRBK2 | 1.30776855 |
| 27 | MYLK | 1.27094283 |
| 28 | MAP4K2 | 1.24346871 |
| 29 | NUAK1 | 1.20568959 |
| 30 | SYK | 0.95166894 |
| 31 | PLK3 | 0.93878022 |
| 32 | GRK7 | 0.92293499 |
| 33 | SRPK1 | 0.91021467 |
| 34 | AURKB | 0.87926229 |
| 35 | GRK5 | 0.86156517 |
| 36 | MAP2K7 | 0.84090419 |
| 37 | WNK4 | 0.83831378 |
| 38 | RPS6KA5 | 0.83624480 |
| 39 | CDC7 | 0.80482632 |
| 40 | STK39 | 0.80305510 |
| 41 | DAPK1 | 0.78304328 |
| 42 | WNK3 | 0.77887771 |
| 43 | TRIM28 | 0.76210733 |
| 44 | AURKA | 0.74841208 |
| 45 | MAP4K1 | 0.74052538 |
| 46 | NME1 | 0.73376045 |
| 47 | TNIK | 0.73048294 |
| 48 | TSSK6 | 0.69203475 |
| 49 | CSNK1G3 | 0.67530734 |
| 50 | MAP2K2 | 0.64283052 |
| 51 | MAP3K4 | 0.62968293 |
| 52 | INSRR | 0.61889257 |
| 53 | MAPKAPK5 | 0.61162125 |
| 54 | TRPM7 | 0.61111707 |
| 55 | MAP3K11 | 0.60672758 |
| 56 | EIF2AK3 | 0.58489663 |
| 57 | FES | 0.57628202 |
| 58 | FRK | 0.56026843 |
| 59 | CSNK1A1L | 0.52867750 |
| 60 | CSNK1G2 | 0.52636774 |
| 61 | ERBB3 | 0.50764398 |
| 62 | DAPK3 | 0.48272593 |
| 63 | CSNK1G1 | 0.44528039 |
| 64 | PLK1 | 0.43865686 |
| 65 | MAP3K5 | 0.43649199 |
| 66 | LYN | 0.42085968 |
| 67 | MATK | 0.41308739 |
| 68 | ERBB2 | 0.40986005 |
| 69 | PRKCQ | 0.40520300 |
| 70 | LCK | 0.39731595 |
| 71 | CSK | 0.38763920 |
| 72 | DYRK2 | 0.37357528 |
| 73 | PASK | 0.36463316 |
| 74 | MAPK13 | 0.35457662 |
| 75 | PAK3 | 0.34901092 |
| 76 | TNK2 | 0.34545065 |
| 77 | BTK | 0.34520964 |
| 78 | PAK4 | 0.33324374 |
| 79 | NTRK1 | 0.33298671 |
| 80 | GRK6 | 0.33146392 |
| 81 | TAF1 | 0.32769712 |
| 82 | STK10 | 0.32232035 |
| 83 | ATR | 0.31363253 |
| 84 | CSNK2A1 | 0.31322539 |
| 85 | BCR | 0.31260313 |
| 86 | BRSK1 | 0.29999181 |
| 87 | CLK1 | 0.29901882 |
| 88 | EPHA4 | 0.29785741 |
| 89 | TTK | 0.29771298 |
| 90 | PLK2 | 0.27613433 |
| 91 | CDK3 | 0.26929675 |
| 92 | TGFBR2 | 0.26835100 |
| 93 | CHEK2 | 0.26571518 |
| 94 | ABL2 | 0.26406251 |
| 95 | CSNK2A2 | 0.24993000 |
| 96 | ZAP70 | 0.24685055 |
| 97 | CHEK1 | 0.23548283 |
| 98 | PRKD1 | 0.23111568 |
| 99 | BMPR1B | 0.22802793 |
| 100 | SCYL2 | 0.22022699 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 6.03036746 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.17817170 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.61664135 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.19966673 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.93693642 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.60155823 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.44636190 |
| 8 | DNA replication_Homo sapiens_hsa03030 | 2.44622934 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.37243142 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.33024960 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.29123550 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.10265209 |
| 13 | Ribosome_Homo sapiens_hsa03010 | 1.98320581 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.95641410 |
| 15 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.87083943 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.71566422 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.69061554 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.69046575 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.68142493 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.68065812 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.61098699 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.53845025 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.50367149 |
| 24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.48911738 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.47728592 |
| 26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.42661373 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.32801783 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.32430797 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.14585543 |
| 30 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.12618312 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.07337715 |
| 32 | Purine metabolism_Homo sapiens_hsa00230 | 1.05527365 |
| 33 | RNA degradation_Homo sapiens_hsa03018 | 1.02499754 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.01469291 |
| 35 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.99048629 |
| 36 | Base excision repair_Homo sapiens_hsa03410 | 0.96160892 |
| 37 | Alcoholism_Homo sapiens_hsa05034 | 0.94516949 |
| 38 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.92394544 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 0.85164867 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.83794420 |
| 41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.83115495 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82690462 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.78297964 |
| 44 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.77955288 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.74898219 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.73711481 |
| 47 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.70295716 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69446631 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.68045451 |
| 50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.66240365 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.65556169 |
| 52 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.64510375 |
| 53 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.62729275 |
| 54 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.62610491 |
| 55 | Asthma_Homo sapiens_hsa05310 | 0.62478420 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62466591 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61041297 |
| 58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60570258 |
| 59 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60295125 |
| 60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59954626 |
| 61 | Shigellosis_Homo sapiens_hsa05131 | 0.59510115 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.59267363 |
| 63 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.59002905 |
| 64 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.58586273 |
| 65 | Viral myocarditis_Homo sapiens_hsa05416 | 0.58557457 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.56663334 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.56400059 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54253170 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51076077 |
| 70 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49070842 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46649621 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45874186 |
| 73 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.44455284 |
| 74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42786112 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41852580 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.41002315 |
| 77 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.40828961 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.40720672 |
| 79 | Cell cycle_Homo sapiens_hsa04110 | 0.38084561 |
| 80 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.37204531 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36744470 |
| 82 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.34590655 |
| 83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.34099594 |
| 84 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32016687 |
| 85 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.31719105 |
| 86 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.31665532 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.31216296 |
| 88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.31118175 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.30890311 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.29927293 |
| 91 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.29604963 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29163256 |
| 93 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.28421858 |
| 94 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.27338515 |
| 95 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.27153404 |
| 96 | Measles_Homo sapiens_hsa05162 | 0.25449856 |
| 97 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.24566176 |
| 98 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.24504658 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.23905680 |
| 100 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.22762751 |

