ERHP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sequestering of actin monomers (GO:0042989)8.21314754
2regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450917.25785010
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.33611883
4ATP synthesis coupled proton transport (GO:0015986)5.71748283
5energy coupled proton transport, down electrochemical gradient (GO:0015985)5.71748283
6Arp2/3 complex-mediated actin nucleation (GO:0034314)5.33760383
7DNA deamination (GO:0045006)5.14300206
8proteasome assembly (GO:0043248)5.01117985
9regulation of cellular amino acid metabolic process (GO:0006521)4.91579164
10negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.79940831
11DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.75701185
12actin nucleation (GO:0045010)4.68843620
13signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.66473470
14signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.66473470
15signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.66473470
16signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.62315744
17intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.62315744
18mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.59435354
19signal transduction involved in DNA integrity checkpoint (GO:0072401)4.56339499
20signal transduction involved in DNA damage checkpoint (GO:0072422)4.56339499
21signal transduction involved in cell cycle checkpoint (GO:0072395)4.52351841
22positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.46471195
23respiratory electron transport chain (GO:0022904)4.45417193
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:4.34520425
25negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.33604738
26negative regulation of ligase activity (GO:0051352)4.33604738
27electron transport chain (GO:0022900)4.33194462
28regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.27345357
29anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.12688366
30antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)4.03743664
31negative regulation by host of viral transcription (GO:0043922)3.97678487
32cytidine metabolic process (GO:0046087)3.86734544
33cytidine catabolic process (GO:0006216)3.86734544
34cytidine deamination (GO:0009972)3.86734544
35positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.73219546
36positive regulation of ligase activity (GO:0051351)3.69890298
37DNA ligation (GO:0006266)3.63930704
387-methylguanosine mRNA capping (GO:0006370)3.62583908
39positive regulation of cell cycle arrest (GO:0071158)3.61193927
40DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.56673005
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.54280351
42cytolysis (GO:0019835)3.53015440
437-methylguanosine RNA capping (GO:0009452)3.52866549
44RNA capping (GO:0036260)3.52866549
45regulation of cellular amine metabolic process (GO:0033238)3.52068806
46protein neddylation (GO:0045116)3.51238319
47rRNA modification (GO:0000154)3.44909442
48inositol phosphate dephosphorylation (GO:0046855)3.44600151
49phosphorylated carbohydrate dephosphorylation (GO:0046838)3.44600151
50antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.41531256
51gonadal mesoderm development (GO:0007506)3.40973219
52purine deoxyribonucleotide catabolic process (GO:0009155)3.34927607
53RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.31515703
54tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.31515703
55hydrogen ion transmembrane transport (GO:1902600)3.25443894
56chaperone-mediated protein transport (GO:0072321)3.25340828
57platelet dense granule organization (GO:0060155)3.25222152
58protein complex biogenesis (GO:0070271)3.24387259
59mitochondrial respiratory chain complex assembly (GO:0033108)3.19561730
60regulation of ubiquitin-protein transferase activity (GO:0051438)3.18877722
61regulation of ligase activity (GO:0051340)3.18585643
62transcription elongation from RNA polymerase III promoter (GO:0006385)3.15357381
63termination of RNA polymerase III transcription (GO:0006386)3.15357381
64negative regulation of stress fiber assembly (GO:0051497)3.15355334
65negative regulation of G1/S transition of mitotic cell cycle (GO:2000134)3.14197598
66negative regulation of cell cycle G1/S phase transition (GO:1902807)3.14197598
67pyrimidine ribonucleoside catabolic process (GO:0046133)3.13041814
68nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.12070370
69apoptotic DNA fragmentation (GO:0006309)3.05196570
70regulation of cell cycle arrest (GO:0071156)3.00101722
71proton transport (GO:0015992)2.99454062
72ubiquinone biosynthetic process (GO:0006744)2.97460845
73viral mRNA export from host cell nucleus (GO:0046784)2.96716010
74hydrogen transport (GO:0006818)2.95564068
75signal transduction in response to DNA damage (GO:0042770)2.95021384
76inositol phosphate catabolic process (GO:0071545)2.94785570
77GDP-mannose metabolic process (GO:0019673)2.94266259
78negative regulation of protein ubiquitination (GO:0031397)2.94066940
79purine nucleoside triphosphate biosynthetic process (GO:0009145)2.92488476
80positive regulation of actin filament depolymerization (GO:0030836)2.92447760
81ATP biosynthetic process (GO:0006754)2.88632694
82cullin deneddylation (GO:0010388)2.88476605
83purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.83187638
84regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.81984161
85regulation of mitotic spindle checkpoint (GO:1903504)2.81984161
86regulation of double-strand break repair via homologous recombination (GO:0010569)2.81960626
87negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.80169934
88base-excision repair, AP site formation (GO:0006285)2.79609814
89rRNA methylation (GO:0031167)2.76729986
90ubiquinone metabolic process (GO:0006743)2.76531743
91GPI anchor biosynthetic process (GO:0006506)2.74251655
92spermatid nucleus differentiation (GO:0007289)2.71958733
93CENP-A containing nucleosome assembly (GO:0034080)2.71202356
94GPI anchor metabolic process (GO:0006505)2.69522801
95histone mRNA metabolic process (GO:0008334)2.68845339
96GTP biosynthetic process (GO:0006183)2.65944963
97mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.64085675
98mitochondrial respiratory chain complex I assembly (GO:0032981)2.64085675
99NADH dehydrogenase complex assembly (GO:0010257)2.64085675
100adenosine metabolic process (GO:0046085)2.62936679

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.71450263
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.31715820
3E2F7_22180533_ChIP-Seq_HELA_Human3.46100891
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.39156843
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.26758580
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.13718522
7CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.06834726
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.94733733
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.87393116
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.84723483
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.79577405
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.78808350
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.70486907
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.70117987
15VDR_23849224_ChIP-Seq_CD4+_Human2.62222779
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.57341398
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.44131752
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34214403
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.22744425
20ELK1_19687146_ChIP-ChIP_HELA_Human2.21495425
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.16275676
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.14386129
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.10564039
24NOTCH1_21737748_ChIP-Seq_TLL_Human2.05599571
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.01995797
26IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.99574291
27IRF8_22096565_ChIP-ChIP_GC-B_Human1.98002351
28ZNF274_21170338_ChIP-Seq_K562_Hela1.96988895
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.83932072
30FOXP3_21729870_ChIP-Seq_TREG_Human1.79961861
31VDR_22108803_ChIP-Seq_LS180_Human1.79591840
32EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.79487017
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.70634265
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66452153
35MYC_18940864_ChIP-ChIP_HL60_Human1.66242518
36MYC_18358816_ChIP-ChIP_MESCs_Mouse1.63730429
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.60395784
38FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.58621481
39IRF8_21731497_ChIP-ChIP_J774_Mouse1.57341179
40MYC_18555785_ChIP-Seq_MESCs_Mouse1.54982222
41ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.54844519
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.52640762
43MYC_19030024_ChIP-ChIP_MESCs_Mouse1.51497443
44YY1_21170310_ChIP-Seq_MESCs_Mouse1.48391300
45E2F1_18555785_ChIP-Seq_MESCs_Mouse1.40277508
46POU5F1_16153702_ChIP-ChIP_HESCs_Human1.38650039
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.38469145
48DCP1A_22483619_ChIP-Seq_HELA_Human1.36598976
49POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33245735
50PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32647385
51GATA3_26560356_Chip-Seq_TH2_Human1.30155853
52CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.27653705
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.26656969
54CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26355917
55MYB_26560356_Chip-Seq_TH2_Human1.25724353
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.25603474
57EZH2_22144423_ChIP-Seq_EOC_Human1.24376373
58NELFA_20434984_ChIP-Seq_ESCs_Mouse1.23516024
59TP53_22573176_ChIP-Seq_HFKS_Human1.22523958
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22488734
61GABP_19822575_ChIP-Seq_HepG2_Human1.21879090
62XRN2_22483619_ChIP-Seq_HELA_Human1.21395330
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.18893762
64CIITA_25753668_ChIP-Seq_RAJI_Human1.17168238
65EWS_26573619_Chip-Seq_HEK293_Human1.16243569
66PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.15845505
67MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.15399196
68HTT_18923047_ChIP-ChIP_STHdh_Human1.14493428
69TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.13716597
70SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13183855
71TAF15_26573619_Chip-Seq_HEK293_Human1.13086605
72SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.09186249
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.08351598
74FOXA1_25329375_ChIP-Seq_VCAP_Human1.08351598
75FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.08280676
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08093079
77FUS_26573619_Chip-Seq_HEK293_Human1.06748564
78AUTS2_25519132_ChIP-Seq_293T-REX_Human1.06332114
79TTF2_22483619_ChIP-Seq_HELA_Human1.03836029
80PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03505345
81GATA3_27048872_Chip-Seq_THYMUS_Human1.02056462
82ERG_20517297_ChIP-Seq_VCAP_Human1.01076167
83EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99557667
84STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97442949
85PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95867114
86GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95669678
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95139287
88CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94508625
89FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.94095639
90GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.93238406
91EGR1_23403033_ChIP-Seq_LIVER_Mouse0.92248958
92STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.92211883
93FOXM1_23109430_ChIP-Seq_U2OS_Human0.91724493
94NFE2_27457419_Chip-Seq_LIVER_Mouse0.91395464
95TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.89794594
96AR_20517297_ChIP-Seq_VCAP_Human0.88499273
97NCOR_22424771_ChIP-Seq_293T_Human0.88251293
98PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86410434
99LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.86233283
100FOXA1_21572438_ChIP-Seq_LNCaP_Human0.84542551

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.37732227
2MP0002102_abnormal_ear_morphology3.13570762
3MP0003646_muscle_fatigue3.02619138
4MP0002166_altered_tumor_susceptibility2.89719247
5MP0005084_abnormal_gallbladder_morpholo2.85435868
6MP0009697_abnormal_copulation2.82566508
7MP0000372_irregular_coat_pigmentation2.76684481
8MP0004147_increased_porphyrin_level2.76107725
9MP0004957_abnormal_blastocyst_morpholog2.61922253
10MP0002006_tumorigenesis2.34767962
11MP0006072_abnormal_retinal_apoptosis2.34505313
12MP0008058_abnormal_DNA_repair2.22970896
13MP0005167_abnormal_blood-brain_barrier2.22614521
14MP0002837_dystrophic_cardiac_calcinosis2.05345963
15MP0002234_abnormal_pharynx_morphology2.04944325
16MP0003786_premature_aging2.02938407
17MP0009785_altered_susceptibility_to1.99660056
18MP0001919_abnormal_reproductive_system1.97726880
19MP0003693_abnormal_embryo_hatching1.97642413
20MP0003724_increased_susceptibility_to1.96536855
21MP0003763_abnormal_thymus_physiology1.74977785
22MP0001879_abnormal_lymphatic_vessel1.66657232
23MP0009333_abnormal_splenocyte_physiolog1.66550705
24MP0010094_abnormal_chromosome_stability1.63539333
25MP0003806_abnormal_nucleotide_metabolis1.56784602
26MP0004145_abnormal_muscle_electrophysio1.54539182
27MP0005377_hearing/vestibular/ear_phenot1.51932677
28MP0003878_abnormal_ear_physiology1.51932677
29MP0005000_abnormal_immune_tolerance1.45842531
30MP0005389_reproductive_system_phenotype1.43989005
31MP0005253_abnormal_eye_physiology1.42891840
32MP0003195_calcinosis1.37412887
33MP0006054_spinal_hemorrhage1.35777848
34MP0005645_abnormal_hypothalamus_physiol1.33379189
35MP0002420_abnormal_adaptive_immunity1.33323478
36MP0001727_abnormal_embryo_implantation1.33237452
37MP0001819_abnormal_immune_cell1.32819357
38MP0001800_abnormal_humoral_immune1.30339970
39MP0003866_abnormal_defecation1.29536443
40MP0003011_delayed_dark_adaptation1.29466052
41MP0005075_abnormal_melanosome_morpholog1.28546247
42MP0001835_abnormal_antigen_presentation1.26193157
43MP0002723_abnormal_immune_serum1.25884141
44MP0002090_abnormal_vision1.21715566
45MP0006036_abnormal_mitochondrial_physio1.18892145
46MP0006276_abnormal_autonomic_nervous1.18526017
47MP0008932_abnormal_embryonic_tissue1.15373350
48MP0003880_abnormal_central_pattern1.14841800
49MP0001661_extended_life_span1.14782936
50MP0002160_abnormal_reproductive_system1.14207254
51MP0002277_abnormal_respiratory_mucosa1.13534348
52MP0001293_anophthalmia1.13383811
53MP0005646_abnormal_pituitary_gland1.12236599
54MP0002938_white_spotting1.11113003
55MP0002876_abnormal_thyroid_physiology1.09096952
56MP0002452_abnormal_antigen_presenting1.08177951
57MP0005551_abnormal_eye_electrophysiolog1.08081549
58MP0006292_abnormal_olfactory_placode1.03693401
59MP0005025_abnormal_response_to1.01293366
60MP0000631_abnormal_neuroendocrine_gland0.98160509
61MP0003567_abnormal_fetal_cardiomyocyte0.97700987
62MP0004084_abnormal_cardiac_muscle0.96202554
63MP0004215_abnormal_myocardial_fiber0.95191181
64MP0002693_abnormal_pancreas_physiology0.94381512
65MP0004036_abnormal_muscle_relaxation0.92700309
66MP0008007_abnormal_cellular_replicative0.87479055
67MP0002398_abnormal_bone_marrow0.87460277
68MP0001845_abnormal_inflammatory_respons0.86194293
69MP0002210_abnormal_sex_determination0.85727086
70MP0006035_abnormal_mitochondrial_morpho0.83250991
71MP0008775_abnormal_heart_ventricle0.82961180
72MP0002928_abnormal_bile_duct0.82338561
73MP0000689_abnormal_spleen_morphology0.81160978
74MP0003718_maternal_effect0.79567258
75MP0000716_abnormal_immune_system0.78444410
76MP0002405_respiratory_system_inflammati0.77094911
77MP0001929_abnormal_gametogenesis0.76703994
78MP0009046_muscle_twitch0.75388943
79MP0001790_abnormal_immune_system0.73637414
80MP0005387_immune_system_phenotype0.73637414
81MP0009764_decreased_sensitivity_to0.73366785
82MP0000685_abnormal_immune_system0.73357014
83MP0002933_joint_inflammation0.73313058
84MP0003137_abnormal_impulse_conducting0.72623457
85MP0003111_abnormal_nucleus_morphology0.71586281
86MP0001485_abnormal_pinna_reflex0.71052178
87MP0001145_abnormal_male_reproductive0.70793807
88MP0008875_abnormal_xenobiotic_pharmacok0.70695929
89MP0008872_abnormal_physiological_respon0.69679040
90MP0003448_altered_tumor_morphology0.68714813
91MP0001119_abnormal_female_reproductive0.67755179
92MP0002429_abnormal_blood_cell0.67617970
93MP0000653_abnormal_sex_gland0.67140479
94MP0001544_abnormal_cardiovascular_syste0.66042604
95MP0005385_cardiovascular_system_phenoty0.66042604
96MP0002722_abnormal_immune_system0.65284460
97MP0000703_abnormal_thymus_morphology0.65144577
98MP0001986_abnormal_taste_sensitivity0.63723940
99MP0002272_abnormal_nervous_system0.62407194
100MP0002148_abnormal_hypersensitivity_rea0.62344033

Predicted human phenotypes

RankGene SetZ-score
1Increased hepatocellular lipid droplets (HP:0006565)4.89471278
2Mitochondrial inheritance (HP:0001427)4.67502100
3Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.60495680
4Lipid accumulation in hepatocytes (HP:0006561)4.17843684
5Acute necrotizing encephalopathy (HP:0006965)4.16946423
6Renal Fanconi syndrome (HP:0001994)4.04519149
7Abnormal mitochondria in muscle tissue (HP:0008316)3.88466336
8Increased intramyocellular lipid droplets (HP:0012240)3.83722783
9IgG deficiency (HP:0004315)3.81602101
10Hepatic necrosis (HP:0002605)3.79686997
11IgM deficiency (HP:0002850)3.71136813
12Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.59389958
13Hepatocellular necrosis (HP:0001404)3.56882369
14Increased CSF lactate (HP:0002490)3.53900022
15Progressive macrocephaly (HP:0004481)3.52527038
16Exertional dyspnea (HP:0002875)3.38649727
17Type I transferrin isoform profile (HP:0003642)3.37155637
18Colon cancer (HP:0003003)3.26788973
19Stomach cancer (HP:0012126)3.26297042
20Acute encephalopathy (HP:0006846)3.23168515
21Prostate neoplasm (HP:0100787)3.15229265
22Increased muscle lipid content (HP:0009058)2.96322320
23Aplastic anemia (HP:0001915)2.92107459
24Abnormality of midbrain morphology (HP:0002418)2.91645687
25Molar tooth sign on MRI (HP:0002419)2.91645687
26Generalized aminoaciduria (HP:0002909)2.86914022
27Increased serum lactate (HP:0002151)2.85466305
28Exercise intolerance (HP:0003546)2.78739853
29Decreased activity of mitochondrial respiratory chain (HP:0008972)2.78517469
30Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.78517469
31Cerebral edema (HP:0002181)2.74906135
32Increased IgM level (HP:0003496)2.71499620
33Reduced antithrombin III activity (HP:0001976)2.70685302
34Abnormality of urine glucose concentration (HP:0011016)2.68545315
35Glycosuria (HP:0003076)2.68545315
36Abnormality of the prostate (HP:0008775)2.64203671
37T lymphocytopenia (HP:0005403)2.60307673
383-Methylglutaconic aciduria (HP:0003535)2.57509875
39Oral leukoplakia (HP:0002745)2.50931277
40Abnormality of T cell number (HP:0011839)2.50704257
41Pancytopenia (HP:0001876)2.50504556
42Abnormality of fatty-acid metabolism (HP:0004359)2.43447969
43Abolished electroretinogram (ERG) (HP:0000550)2.42556830
44Hypomagnesemia (HP:0002917)2.40200694
45Progressive muscle weakness (HP:0003323)2.39708849
46Abnormality of renal resorption (HP:0011038)2.38983191
47Tetany (HP:0001281)2.37457736
48Pancreatic fibrosis (HP:0100732)2.37156096
49Cellular immunodeficiency (HP:0005374)2.33223377
50Lactic acidosis (HP:0003128)2.32253821
51Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.29906793
52Abnormal protein N-linked glycosylation (HP:0012347)2.29906793
53Abnormal protein glycosylation (HP:0012346)2.29906793
54Abnormal glycosylation (HP:0012345)2.29906793
55Amyotrophic lateral sclerosis (HP:0007354)2.23576527
56Chronic diarrhea (HP:0002028)2.23358574
57Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.22187706
58Pancreatic cysts (HP:0001737)2.21578442
59Optic disc pallor (HP:0000543)2.21360663
60Severe combined immunodeficiency (HP:0004430)2.19942310
61Respiratory failure (HP:0002878)2.18762460
62Renal cortical cysts (HP:0000803)2.15921938
63Atrophy/Degeneration involving motor neurons (HP:0007373)2.14783238
64Chronic hepatic failure (HP:0100626)2.12509999
65True hermaphroditism (HP:0010459)2.11883217
66Respiratory difficulties (HP:0002880)2.09962328
67Birth length less than 3rd percentile (HP:0003561)2.09251022
68Increased circulating renin level (HP:0000848)2.06764014
69Hypoalbuminemia (HP:0003073)2.05328032
70Abnormal albumin level (HP:0012116)2.05328032
71Aplasia/hypoplasia of the uterus (HP:0008684)2.04956917
72Hyperphosphaturia (HP:0003109)2.03015734
73Abnormality of T cells (HP:0002843)2.01195194
74Hypoglycemic coma (HP:0001325)1.99207007
75Combined immunodeficiency (HP:0005387)1.98367865
76Agitation (HP:0000713)1.95270750
77Emotional lability (HP:0000712)1.92482938
78Pendular nystagmus (HP:0012043)1.91344518
79Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.91074640
80Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90148867
81Hypoproteinemia (HP:0003075)1.89359101
82Medial flaring of the eyebrow (HP:0010747)1.85134612
83Abnormality of dicarboxylic acid metabolism (HP:0010995)1.83173221
84Dicarboxylic aciduria (HP:0003215)1.83173221
85Sclerocornea (HP:0000647)1.81815004
86Congenital primary aphakia (HP:0007707)1.81676112
87Nausea (HP:0002018)1.80319520
88Reticulocytopenia (HP:0001896)1.80024625
89Gait imbalance (HP:0002141)1.74807058
90Hypothermia (HP:0002045)1.74587405
91Abnormality of the renal cortex (HP:0011035)1.74329324
92Abnormality of magnesium homeostasis (HP:0004921)1.73777582
93Sensory axonal neuropathy (HP:0003390)1.72713156
94Female pseudohermaphroditism (HP:0010458)1.72136913
95Abnormality of the anterior horn cell (HP:0006802)1.71052699
96Degeneration of anterior horn cells (HP:0002398)1.71052699
97Testicular atrophy (HP:0000029)1.69992248
98Hypoplasia of the uterus (HP:0000013)1.69871690
99Constricted visual fields (HP:0001133)1.69102949
100Congenital stationary night blindness (HP:0007642)1.68919369

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK24.42645293
2KDR4.29885100
3TIE14.28042325
4BUB13.66117836
5VRK23.39310140
6MAP3K123.24160575
7LIMK13.08402968
8TXK2.94549642
9MST42.89575517
10ZAK2.88415533
11TESK12.80720785
12BCKDK2.75326537
13VRK12.53060027
14STK162.11338578
15TLK11.91405595
16DYRK31.82304965
17TAOK31.80508580
18GRK11.78714792
19TEC1.55728951
20PLK41.53079544
21BLK1.51494210
22NEK11.47687424
23ITK1.45839298
24RPS6KA41.44127214
25MAPKAPK31.31787973
26ADRBK21.30776855
27MYLK1.27094283
28MAP4K21.24346871
29NUAK11.20568959
30SYK0.95166894
31PLK30.93878022
32GRK70.92293499
33SRPK10.91021467
34AURKB0.87926229
35GRK50.86156517
36MAP2K70.84090419
37WNK40.83831378
38RPS6KA50.83624480
39CDC70.80482632
40STK390.80305510
41DAPK10.78304328
42WNK30.77887771
43TRIM280.76210733
44AURKA0.74841208
45MAP4K10.74052538
46NME10.73376045
47TNIK0.73048294
48TSSK60.69203475
49CSNK1G30.67530734
50MAP2K20.64283052
51MAP3K40.62968293
52INSRR0.61889257
53MAPKAPK50.61162125
54TRPM70.61111707
55MAP3K110.60672758
56EIF2AK30.58489663
57FES0.57628202
58FRK0.56026843
59CSNK1A1L0.52867750
60CSNK1G20.52636774
61ERBB30.50764398
62DAPK30.48272593
63CSNK1G10.44528039
64PLK10.43865686
65MAP3K50.43649199
66LYN0.42085968
67MATK0.41308739
68ERBB20.40986005
69PRKCQ0.40520300
70LCK0.39731595
71CSK0.38763920
72DYRK20.37357528
73PASK0.36463316
74MAPK130.35457662
75PAK30.34901092
76TNK20.34545065
77BTK0.34520964
78PAK40.33324374
79NTRK10.33298671
80GRK60.33146392
81TAF10.32769712
82STK100.32232035
83ATR0.31363253
84CSNK2A10.31322539
85BCR0.31260313
86BRSK10.29999181
87CLK10.29901882
88EPHA40.29785741
89TTK0.29771298
90PLK20.27613433
91CDK30.26929675
92TGFBR20.26835100
93CHEK20.26571518
94ABL20.26406251
95CSNK2A20.24993000
96ZAP700.24685055
97CHEK10.23548283
98PRKD10.23111568
99BMPR1B0.22802793
100SCYL20.22022699

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030506.03036746
2Oxidative phosphorylation_Homo sapiens_hsa001904.17817170
3Parkinsons disease_Homo sapiens_hsa050123.61664135
4Protein export_Homo sapiens_hsa030603.19966673
5RNA polymerase_Homo sapiens_hsa030202.93693642
6Alzheimers disease_Homo sapiens_hsa050102.60155823
7Huntingtons disease_Homo sapiens_hsa050162.44636190
8DNA replication_Homo sapiens_hsa030302.44622934
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.37243142
10Mismatch repair_Homo sapiens_hsa034302.33024960
11Primary immunodeficiency_Homo sapiens_hsa053402.29123550
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.10265209
13Ribosome_Homo sapiens_hsa030101.98320581
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.95641410
15Systemic lupus erythematosus_Homo sapiens_hsa053221.87083943
16Cardiac muscle contraction_Homo sapiens_hsa042601.71566422
17Homologous recombination_Homo sapiens_hsa034401.69061554
18Antigen processing and presentation_Homo sapiens_hsa046121.69046575
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68142493
20Autoimmune thyroid disease_Homo sapiens_hsa053201.68065812
21Spliceosome_Homo sapiens_hsa030401.61098699
22Allograft rejection_Homo sapiens_hsa053301.53845025
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.50367149
24Graft-versus-host disease_Homo sapiens_hsa053321.48911738
25Basal transcription factors_Homo sapiens_hsa030221.47728592
26Sulfur metabolism_Homo sapiens_hsa009201.42661373
27Type I diabetes mellitus_Homo sapiens_hsa049401.32801783
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.32430797
29Pyrimidine metabolism_Homo sapiens_hsa002401.14585543
30Butanoate metabolism_Homo sapiens_hsa006501.12618312
31Phototransduction_Homo sapiens_hsa047441.07337715
32Purine metabolism_Homo sapiens_hsa002301.05527365
33RNA degradation_Homo sapiens_hsa030181.02499754
34Fanconi anemia pathway_Homo sapiens_hsa034601.01469291
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.99048629
36Base excision repair_Homo sapiens_hsa034100.96160892
37Alcoholism_Homo sapiens_hsa050340.94516949
38Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92394544
39Peroxisome_Homo sapiens_hsa041460.85164867
40Nucleotide excision repair_Homo sapiens_hsa034200.83794420
41Hematopoietic cell lineage_Homo sapiens_hsa046400.83115495
42Caffeine metabolism_Homo sapiens_hsa002320.82690462
43RNA transport_Homo sapiens_hsa030130.78297964
44Folate biosynthesis_Homo sapiens_hsa007900.77955288
45One carbon pool by folate_Homo sapiens_hsa006700.74898219
46Rheumatoid arthritis_Homo sapiens_hsa053230.73711481
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70295716
48Maturity onset diabetes of the young_Homo sapiens_hsa049500.69446631
49Intestinal immune network for IgA production_Homo sapiens_hsa046720.68045451
50Vitamin B6 metabolism_Homo sapiens_hsa007500.66240365
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.65556169
52Primary bile acid biosynthesis_Homo sapiens_hsa001200.64510375
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.62729275
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.62610491
55Asthma_Homo sapiens_hsa053100.62478420
56Olfactory transduction_Homo sapiens_hsa047400.62466591
57Glutathione metabolism_Homo sapiens_hsa004800.61041297
58Epstein-Barr virus infection_Homo sapiens_hsa051690.60570258
59Fatty acid elongation_Homo sapiens_hsa000620.60295125
60Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59954626
61Shigellosis_Homo sapiens_hsa051310.59510115
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59267363
63Non-homologous end-joining_Homo sapiens_hsa034500.59002905
64Propanoate metabolism_Homo sapiens_hsa006400.58586273
65Viral myocarditis_Homo sapiens_hsa054160.58557457
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56663334
67Regulation of autophagy_Homo sapiens_hsa041400.56400059
68Metabolic pathways_Homo sapiens_hsa011000.54253170
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51076077
70Collecting duct acid secretion_Homo sapiens_hsa049660.49070842
71Chemical carcinogenesis_Homo sapiens_hsa052040.46649621
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45874186
73Pyruvate metabolism_Homo sapiens_hsa006200.44455284
74Selenocompound metabolism_Homo sapiens_hsa004500.42786112
75Steroid hormone biosynthesis_Homo sapiens_hsa001400.41852580
76Retinol metabolism_Homo sapiens_hsa008300.41002315
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40828961
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.40720672
79Cell cycle_Homo sapiens_hsa041100.38084561
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37204531
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.36744470
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34590655
83Oocyte meiosis_Homo sapiens_hsa041140.34099594
84Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32016687
85Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.31719105
86Herpes simplex infection_Homo sapiens_hsa051680.31665532
87Fat digestion and absorption_Homo sapiens_hsa049750.31216296
88mRNA surveillance pathway_Homo sapiens_hsa030150.31118175
89T cell receptor signaling pathway_Homo sapiens_hsa046600.30890311
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29927293
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.29604963
92Vitamin digestion and absorption_Homo sapiens_hsa049770.29163256
93Tryptophan metabolism_Homo sapiens_hsa003800.28421858
94Steroid biosynthesis_Homo sapiens_hsa001000.27338515
95Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.27153404
96Measles_Homo sapiens_hsa051620.25449856
97Linoleic acid metabolism_Homo sapiens_hsa005910.24566176
98Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.24504658
99Morphine addiction_Homo sapiens_hsa050320.23905680
1002-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.22762751

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »