ERI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.89258846
2DNA strand elongation involved in DNA replication (GO:0006271)4.64510858
3telomere maintenance via semi-conservative replication (GO:0032201)4.45690111
4protein localization to kinetochore (GO:0034501)4.45407952
5DNA strand elongation (GO:0022616)4.41047606
6synapsis (GO:0007129)4.35769038
7DNA replication initiation (GO:0006270)4.33043015
8telomere maintenance via recombination (GO:0000722)4.15191191
9DNA double-strand break processing (GO:0000729)4.13435619
10mitotic recombination (GO:0006312)4.07778397
11nuclear pore complex assembly (GO:0051292)3.94758030
12protein localization to chromosome, centromeric region (GO:0071459)3.94053282
13ribosomal small subunit assembly (GO:0000028)3.90904001
14nuclear pore organization (GO:0006999)3.86793161
15somatic diversification of immune receptors via somatic mutation (GO:0002566)3.81311517
16somatic hypermutation of immunoglobulin genes (GO:0016446)3.81311517
17DNA replication checkpoint (GO:0000076)3.81276723
18establishment of integrated proviral latency (GO:0075713)3.79275594
19mitotic sister chromatid cohesion (GO:0007064)3.69571977
20mitotic nuclear envelope disassembly (GO:0007077)3.68714132
21regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.65484687
22kinetochore organization (GO:0051383)3.60445428
23proteasome assembly (GO:0043248)3.60272965
24regulation of double-strand break repair via homologous recombination (GO:0010569)3.58518189
25CENP-A containing nucleosome assembly (GO:0034080)3.57970063
26mitotic chromosome condensation (GO:0007076)3.57823292
27replication fork processing (GO:0031297)3.57490075
28chromatin remodeling at centromere (GO:0031055)3.50725268
29regulation of meiosis I (GO:0060631)3.50105995
30mitotic metaphase plate congression (GO:0007080)3.49561450
31telomere maintenance via telomere lengthening (GO:0010833)3.49239349
32DNA catabolic process, exonucleolytic (GO:0000738)3.48181215
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.47024130
34IMP biosynthetic process (GO:0006188)3.45560018
35DNA ligation (GO:0006266)3.42871232
36DNA replication-dependent nucleosome assembly (GO:0006335)3.42671986
37DNA replication-dependent nucleosome organization (GO:0034723)3.42671986
38nuclear envelope disassembly (GO:0051081)3.42276850
39membrane disassembly (GO:0030397)3.42276850
40cytidine metabolic process (GO:0046087)3.40879470
41cytidine catabolic process (GO:0006216)3.40879470
42cytidine deamination (GO:0009972)3.40879470
43DNA replication-independent nucleosome organization (GO:0034724)3.40514146
44DNA replication-independent nucleosome assembly (GO:0006336)3.40514146
45negative regulation of chromosome segregation (GO:0051985)3.38595238
46folic acid-containing compound biosynthetic process (GO:0009396)3.38480855
47regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.37020477
48maturation of SSU-rRNA (GO:0030490)3.36836967
49negative regulation of mitotic sister chromatid separation (GO:2000816)3.35422418
50negative regulation of sister chromatid segregation (GO:0033046)3.35422418
51negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.35422418
52negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.35422418
53negative regulation of mitotic sister chromatid segregation (GO:0033048)3.35422418
54viral transcription (GO:0019083)3.34590117
55non-recombinational repair (GO:0000726)3.33489968
56double-strand break repair via nonhomologous end joining (GO:0006303)3.33489968
57sister chromatid segregation (GO:0000819)3.32302390
58regulation of mitotic sister chromatid separation (GO:0010965)3.31274209
59regulation of mitotic sister chromatid segregation (GO:0033047)3.31274209
60regulation of sister chromatid segregation (GO:0033045)3.31274209
61translational termination (GO:0006415)3.31232614
62regulation of centriole replication (GO:0046599)3.30562154
63translesion synthesis (GO:0019985)3.28368521
64anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.28206064
65mitotic spindle checkpoint (GO:0071174)3.27613876
66negative regulation of DNA-dependent DNA replication (GO:2000104)3.27305821
67protein K6-linked ubiquitination (GO:0085020)3.25532436
68regulation of spindle organization (GO:0090224)3.24626852
69mitotic sister chromatid segregation (GO:0000070)3.22849690
70somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.22253186
71somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.22253186
72isotype switching (GO:0045190)3.22253186
73nucleobase biosynthetic process (GO:0046112)3.21945983
74mitotic spindle assembly checkpoint (GO:0007094)3.21064995
75DNA geometric change (GO:0032392)3.20557495
76DNA duplex unwinding (GO:0032508)3.19811215
77metaphase plate congression (GO:0051310)3.18161267
78regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.17467612
79pyrimidine ribonucleoside catabolic process (GO:0046133)3.16892929
80attachment of spindle microtubules to kinetochore (GO:0008608)3.16605972
81dosage compensation (GO:0007549)3.16338953
82formation of translation preinitiation complex (GO:0001731)3.15829110
83IMP metabolic process (GO:0046040)3.15612540
84response to X-ray (GO:0010165)3.12522858
85pore complex assembly (GO:0046931)3.12065740
86meiotic chromosome segregation (GO:0045132)3.07584698
87piRNA metabolic process (GO:0034587)3.07386870
88mitotic G2/M transition checkpoint (GO:0044818)3.07119983
89negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.04285919
90male meiosis I (GO:0007141)3.02999362
91ribosome assembly (GO:0042255)3.02942553
92chromatin assembly or disassembly (GO:0006333)3.00751050
93establishment of chromosome localization (GO:0051303)2.98569340
94translational elongation (GO:0006414)2.98529675
95translational initiation (GO:0006413)2.95764170
96regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.95352649
97telomere maintenance (GO:0000723)2.94184808
98kinetochore assembly (GO:0051382)2.93325146
99positive regulation of chromosome segregation (GO:0051984)2.92755787
100nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92393337
101telomere organization (GO:0032200)2.91787386
102regulation of DNA endoreduplication (GO:0032875)2.90670407
103regulation of histone H3-K9 methylation (GO:0051570)2.90408782
104histone exchange (GO:0043486)2.88445498
105purine nucleobase biosynthetic process (GO:0009113)2.87541243
106postreplication repair (GO:0006301)2.87435489
107protein localization to chromosome (GO:0034502)2.87253845
108ribosomal large subunit biogenesis (GO:0042273)2.85931153
109DNA topological change (GO:0006265)2.79513223
110negative regulation of RNA splicing (GO:0033119)2.77933895
111regulation of mitotic spindle organization (GO:0060236)2.77059537
112SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.76462334
113deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.75591015
114ribosomal small subunit biogenesis (GO:0042274)2.75501742
115DNA conformation change (GO:0071103)2.71935794
116negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.71540313
117positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.70196178
118positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.70196178
119positive regulation of mitotic sister chromatid separation (GO:1901970)2.70196178
120ribonucleoprotein complex biogenesis (GO:0022613)2.70063165
121nuclear envelope organization (GO:0006998)2.69132261
122mismatch repair (GO:0006298)2.67565591
123regulation of centrosome cycle (GO:0046605)2.67513614
124ribosome biogenesis (GO:0042254)2.66756472
125cotranslational protein targeting to membrane (GO:0006613)2.66654616
126protein targeting to ER (GO:0045047)2.66545846
127regulation of mitotic metaphase/anaphase transition (GO:0030071)2.65860484
128regulation of chromosome segregation (GO:0051983)2.64954237
129chromosome segregation (GO:0007059)2.64765530
130spindle checkpoint (GO:0031577)2.64094546
131regulation of sister chromatid cohesion (GO:0007063)2.62251507
132ATP-dependent chromatin remodeling (GO:0043044)2.61288608
133regulation of nuclear cell cycle DNA replication (GO:0033262)2.61124581
134DNA deamination (GO:0045006)2.59693410
135histone-serine phosphorylation (GO:0035404)2.59389366
136regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.59315144
137maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.59234524
138spindle assembly checkpoint (GO:0071173)2.57546239
139cellular protein complex disassembly (GO:0043624)2.57205629
140Arp2/3 complex-mediated actin nucleation (GO:0034314)2.56764080
141viral life cycle (GO:0019058)2.55894824

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.65063290
2E2F4_17652178_ChIP-ChIP_JURKAT_Human3.95844037
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.50022664
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.24394299
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.17109250
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.08389479
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.96390012
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.79444958
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.38946584
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.31129921
11MYC_22102868_ChIP-Seq_BL_Human2.26707249
12E2F1_21310950_ChIP-Seq_MCF-7_Human2.24331678
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.15148972
14AR_21909140_ChIP-Seq_LNCAP_Human2.13120238
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.07275486
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.07049636
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.05965143
18* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.05261624
19E2F7_22180533_ChIP-Seq_HELA_Human10.1591363
20VDR_23849224_ChIP-Seq_CD4+_Human1.96510935
21GABP_17652178_ChIP-ChIP_JURKAT_Human1.93291215
22CREB1_15753290_ChIP-ChIP_HEK293T_Human1.88118044
23XRN2_22483619_ChIP-Seq_HELA_Human1.87644995
24ELF1_17652178_ChIP-ChIP_JURKAT_Human1.87475271
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.85521473
26TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.81947303
27ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.81046386
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.79750395
29BP1_19119308_ChIP-ChIP_Hs578T_Human1.77576456
30FOXP3_21729870_ChIP-Seq_TREG_Human1.71761780
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70147858
32SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.68558404
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.67795694
34* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.65794232
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.64913630
36ELK1_19687146_ChIP-ChIP_HELA_Human1.63310066
37DCP1A_22483619_ChIP-Seq_HELA_Human1.61186977
38CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.59467699
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.58140962
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57557595
41VDR_21846776_ChIP-Seq_THP-1_Human1.57343305
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56864310
43CIITA_25753668_ChIP-Seq_RAJI_Human1.54498485
44IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.53974923
45SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.53468577
46E2F1_18555785_ChIP-Seq_MESCs_Mouse1.52204846
47MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.51136696
48HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.48815693
49IRF8_22096565_ChIP-ChIP_GC-B_Human1.47206782
50NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.46846934
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.46842027
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.44473949
53* TTF2_22483619_ChIP-Seq_HELA_Human1.43609297
54GABP_19822575_ChIP-Seq_HepG2_Human1.42918572
55MYB_21317192_ChIP-Seq_ERMYB_Mouse1.41528701
56* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.40321534
57MYC_18940864_ChIP-ChIP_HL60_Human1.40148848
58SPI1_23547873_ChIP-Seq_NB4_Human1.39744990
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.36589330
60ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35192862
61SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.34630681
62KDM5A_27292631_Chip-Seq_BREAST_Human1.31587380
63RBPJ_22232070_ChIP-Seq_NCS_Mouse1.30796823
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.30626142
65FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.30319557
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.28261633
67EWS_26573619_Chip-Seq_HEK293_Human1.27624018
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.25618830
69ZNF274_21170338_ChIP-Seq_K562_Hela1.25428824
70TFEB_21752829_ChIP-Seq_HELA_Human1.24005345
71MYB_26560356_Chip-Seq_TH2_Human1.23967239
72YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22646116
73SCL_19346495_ChIP-Seq_HPC-7_Human1.22562961
74POU3F2_20337985_ChIP-ChIP_501MEL_Human1.21537907
75SRF_21415370_ChIP-Seq_HL-1_Mouse1.20072570
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19503388
77MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19319615
78NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17913505
79IRF8_21731497_ChIP-ChIP_J774_Mouse1.17519055
80GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.16398904
81MAF_26560356_Chip-Seq_TH1_Human1.14539555
82TP63_19390658_ChIP-ChIP_HaCaT_Human1.14044134
83MYB_26560356_Chip-Seq_TH1_Human1.12793221
84POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10572954
85POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10164753
86BRD4_27068464_Chip-Seq_AML-cells_Mouse1.09691488
87STAT4_19710469_ChIP-ChIP_TH1__Mouse1.08993283
88HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.07761257
89IRF1_19129219_ChIP-ChIP_H3396_Human1.07300298
90PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06933337
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06821663
92UTX_26944678_Chip-Seq_JUKART_Human1.04660399
93THAP11_20581084_ChIP-Seq_MESCs_Mouse1.03612178
94FUS_26573619_Chip-Seq_HEK293_Human1.03419533
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.00871066
96CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00475896
97RUNX1_22412390_ChIP-Seq_EML_Mouse1.00308626
98HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99474596
99STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98236177
100CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97901651
101DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97493442
102KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97278364
103KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97278364
104KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97278364
105ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.96747682
106IGF1R_20145208_ChIP-Seq_DFB_Human0.96531907
107VDR_24763502_ChIP-Seq_THP-1_Human0.96443974
108NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.94331585
109CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.93463911
110SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.92640277
111FLI1_27457419_Chip-Seq_LIVER_Mouse0.91147323
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.90878747
113ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.90665605
114RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89263849
115VDR_22108803_ChIP-Seq_LS180_Human0.88853446
116GATA2_22383799_ChIP-Seq_G1ME_Mouse0.88786642
117TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88770065
118TCF7_22412390_ChIP-Seq_EML_Mouse0.87527575
119GATA1_22383799_ChIP-Seq_G1ME_Mouse0.87396543
120* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86291530
121STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.86230829
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84213759
123CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84206395
124PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.83481125
125SOX2_16153702_ChIP-ChIP_HESCs_Human0.79227461
126SOX17_20123909_ChIP-Seq_XEN_Mouse0.77010352
127RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.76257416
128SOX2_18555785_ChIP-Seq_MESCs_Mouse0.74680673
129GATA1_22025678_ChIP-Seq_K562_Human0.74499428
130NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.71634639
131HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.71307075
132SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70850054
133YY1_21170310_ChIP-Seq_MESCs_Mouse0.68854745
134CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.67544585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.09839254
2MP0010094_abnormal_chromosome_stability3.98459854
3MP0008057_abnormal_DNA_replication3.48897265
4MP0003111_abnormal_nucleus_morphology3.45223622
5MP0004957_abnormal_blastocyst_morpholog3.22455376
6MP0003077_abnormal_cell_cycle3.20388830
7MP0003718_maternal_effect3.11904327
8MP0002396_abnormal_hematopoietic_system3.01408980
9MP0009697_abnormal_copulation2.70973730
10MP0010352_gastrointestinal_tract_polyps2.56069173
11MP0008058_abnormal_DNA_repair2.46914014
12MP0008007_abnormal_cellular_replicative2.40938740
13MP0004808_abnormal_hematopoietic_stem2.23007343
14MP0003890_abnormal_embryonic-extraembry2.22425715
15MP0010307_abnormal_tumor_latency2.20669295
16MP0000490_abnormal_crypts_of2.11546612
17MP0001835_abnormal_antigen_presentation1.95590262
18MP0003763_abnormal_thymus_physiology1.89487597
19* MP0000350_abnormal_cell_proliferation1.86834769
20MP0008789_abnormal_olfactory_epithelium1.84172607
21MP0001545_abnormal_hematopoietic_system1.81257036
22MP0005397_hematopoietic_system_phenotyp1.81257036
23MP0008932_abnormal_embryonic_tissue1.81256770
24MP0002398_abnormal_bone_marrow1.78373304
25MP0001730_embryonic_growth_arrest1.68842413
26MP0002166_altered_tumor_susceptibility1.66714628
27MP0006292_abnormal_olfactory_placode1.64715372
28MP0001800_abnormal_humoral_immune1.60842664
29MP0000685_abnormal_immune_system1.58849996
30MP0006054_spinal_hemorrhage1.58694031
31MP0005076_abnormal_cell_differentiation1.58664230
32MP0000703_abnormal_thymus_morphology1.56791743
33MP0009333_abnormal_splenocyte_physiolog1.56411159
34MP0001929_abnormal_gametogenesis1.55425022
35MP0003436_decreased_susceptibility_to1.55227228
36MP0002722_abnormal_immune_system1.54314009
37MP0000689_abnormal_spleen_morphology1.53171766
38MP0005499_abnormal_olfactory_system1.52568411
39MP0005394_taste/olfaction_phenotype1.52568411
40MP0002019_abnormal_tumor_incidence1.51581836
41MP0005671_abnormal_response_to1.49290498
42MP0002452_abnormal_antigen_presenting1.47812516
43MP0002006_tumorigenesis1.46464625
44MP0003806_abnormal_nucleotide_metabolis1.41574708
45MP0002420_abnormal_adaptive_immunity1.39735753
46MP0000716_abnormal_immune_system1.38963403
47MP0001819_abnormal_immune_cell1.37956494
48MP0002429_abnormal_blood_cell1.35977412
49MP0000313_abnormal_cell_death1.35074716
50MP0004147_increased_porphyrin_level1.34038708
51MP0003303_peritoneal_inflammation1.32521333
52MP0002723_abnormal_immune_serum1.31888822
53MP0005000_abnormal_immune_tolerance1.30399597
54MP0001697_abnormal_embryo_size1.29786391
55MP0005380_embryogenesis_phenotype1.29046246
56MP0001672_abnormal_embryogenesis/_devel1.29046246
57MP0003300_gastrointestinal_ulcer1.28512601
58MP0009278_abnormal_bone_marrow1.28184294
59MP0009785_altered_susceptibility_to1.25323241
60MP0006035_abnormal_mitochondrial_morpho1.24192379
61MP0003941_abnormal_skin_development1.24165545
62MP0002080_prenatal_lethality1.23592883
63MP0003984_embryonic_growth_retardation1.22376146
64MP0000465_gastrointestinal_hemorrhage1.21995667
65MP0001145_abnormal_male_reproductive1.20856121
66MP0005395_other_phenotype1.20345871
67MP0002088_abnormal_embryonic_growth/wei1.20179514
68MP0010155_abnormal_intestine_physiology1.20087309
69MP0000858_altered_metastatic_potential1.18944647
70MP0002086_abnormal_extraembryonic_tissu1.18708086
71MP0000653_abnormal_sex_gland1.18376281
72MP0002405_respiratory_system_inflammati1.18289864
73MP0001853_heart_inflammation1.17496319
74MP0003123_paternal_imprinting1.17362703
75MP0000427_abnormal_hair_cycle1.17173336
76MP0005025_abnormal_response_to1.16967302
77MP0003786_premature_aging1.16302560
78MP0003567_abnormal_fetal_cardiomyocyte1.14783303
79MP0001119_abnormal_female_reproductive1.13425140
80MP0003937_abnormal_limbs/digits/tail_de1.12002300
81MP0008877_abnormal_DNA_methylation1.08767101
82MP0002095_abnormal_skin_pigmentation1.07592268
83MP0001790_abnormal_immune_system1.05245213
84MP0005387_immune_system_phenotype1.05245213
85MP0001873_stomach_inflammation1.04141339
86MP0002419_abnormal_innate_immunity1.03868249
87* MP0004197_abnormal_fetal_growth/weight/1.03386081
88MP0002163_abnormal_gland_morphology1.03107713
89MP0002085_abnormal_embryonic_tissue1.02581050
90MP0004947_skin_inflammation1.02139430
91MP0003448_altered_tumor_morphology1.00829146
92MP0003950_abnormal_plasma_membrane1.00337669
93MP0003186_abnormal_redox_activity0.98597717
94MP0002233_abnormal_nose_morphology0.97636226
95MP0005174_abnormal_tail_pigmentation0.97235979
96MP0005464_abnormal_platelet_physiology0.96390423
97MP0002160_abnormal_reproductive_system0.96366112
98MP0002084_abnormal_developmental_patter0.95886423
99MP0001293_anophthalmia0.95456374
100MP0000372_irregular_coat_pigmentation0.95006013
101MP0005023_abnormal_wound_healing0.93937059
102MP0002148_abnormal_hypersensitivity_rea0.91208595
103MP0003699_abnormal_female_reproductive0.91016914
104MP0003566_abnormal_cell_adhesion0.86602114
105MP0003221_abnormal_cardiomyocyte_apopto0.84847480
106MP0003698_abnormal_male_reproductive0.84416064
107MP0002877_abnormal_melanocyte_morpholog0.83681549
108MP0002234_abnormal_pharynx_morphology0.83090809
109MP0010678_abnormal_skin_adnexa0.82527548
110MP0001845_abnormal_inflammatory_respons0.82514789
111MP0001915_intracranial_hemorrhage0.81799628
112MP0004185_abnormal_adipocyte_glucose0.79850515
113MP0000569_abnormal_digit_pigmentation0.79645056
114MP0010234_abnormal_vibrissa_follicle0.79184592
115MP0001529_abnormal_vocalization0.77912292
116MP0005621_abnormal_cell_physiology0.77705090
117MP0003705_abnormal_hypodermis_morpholog0.77349616
118MP0003121_genomic_imprinting0.77044644
119MP0002009_preneoplasia0.76623296
120MP0005647_abnormal_sex_gland0.76231494
121MP0005501_abnormal_skin_physiology0.75607109
122MP0000477_abnormal_intestine_morphology0.75097125
123MP0000371_diluted_coat_color0.74455521
124MP0005384_cellular_phenotype0.73873385
125MP0003656_abnormal_erythrocyte_physiolo0.73868996
126MP0000383_abnormal_hair_follicle0.72571132
127MP0000647_abnormal_sebaceous_gland0.72453015
128MP0002132_abnormal_respiratory_system0.72265358
129MP0010030_abnormal_orbit_morphology0.71327276
130MP0008995_early_reproductive_senescence0.71212663
131MP0001191_abnormal_skin_condition0.70896463
132MP0002161_abnormal_fertility/fecundity0.70495736
133MP0000627_abnormal_mammary_gland0.70011794
134MP0005075_abnormal_melanosome_morpholog0.69302704
135MP0003936_abnormal_reproductive_system0.68043734
136MP0001286_abnormal_eye_development0.68037913
137MP0001881_abnormal_mammary_gland0.66865407
138MP0003866_abnormal_defecation0.65881793
139MP0000428_abnormal_craniofacial_morphol0.64715907
140MP0002075_abnormal_coat/hair_pigmentati0.64346790
141MP0001188_hyperpigmentation0.63899130
142MP0005389_reproductive_system_phenotype0.63638666
143MP0003943_abnormal_hepatobiliary_system0.63151911
144MP0001764_abnormal_homeostasis0.63020589
145MP0000733_abnormal_muscle_development0.62998914
146MP0000358_abnormal_cell_content/0.62392684
147MP0002210_abnormal_sex_determination0.61887286
148MP0002092_abnormal_eye_morphology0.60926082

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.04816691
2Reticulocytopenia (HP:0001896)3.96118371
3Chromsome breakage (HP:0040012)3.49822042
4Abnormality of chromosome stability (HP:0003220)3.14632171
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.11945942
6Agnosia (HP:0010524)3.10209574
7Abnormality of cells of the erythroid lineage (HP:0012130)3.05223550
8Nephroblastoma (Wilms tumor) (HP:0002667)3.04512841
9Abnormality of the labia minora (HP:0012880)3.04080184
10Abnormal number of erythroid precursors (HP:0012131)3.00847017
11Thrombocytosis (HP:0001894)2.99549216
12Carpal bone hypoplasia (HP:0001498)2.96410517
13Embryonal renal neoplasm (HP:0011794)2.90511936
14Abnormal lung lobation (HP:0002101)2.89485900
15IgM deficiency (HP:0002850)2.88400785
16Myelodysplasia (HP:0002863)2.81685944
17Colon cancer (HP:0003003)2.80314802
18Volvulus (HP:0002580)2.73571696
19Recurrent viral infections (HP:0004429)2.69767567
20Abnormality of the preputium (HP:0100587)2.67228148
21Horseshoe kidney (HP:0000085)2.64527175
22Meckel diverticulum (HP:0002245)2.64525266
23Selective tooth agenesis (HP:0001592)2.61108006
24Aplastic anemia (HP:0001915)2.60329656
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.57079478
26Pallor (HP:0000980)2.55950722
27Absent radius (HP:0003974)2.55208753
28Oral leukoplakia (HP:0002745)2.52568722
29Abnormality of the ileum (HP:0001549)2.52245870
30Cortical dysplasia (HP:0002539)2.46525407
31Ectopic kidney (HP:0000086)2.46280338
32Lymphoma (HP:0002665)2.44976174
33Basal cell carcinoma (HP:0002671)2.42416725
34Medulloblastoma (HP:0002885)2.42149955
35Absent forearm bone (HP:0003953)2.41342864
36Aplasia involving forearm bones (HP:0009822)2.41342864
37Oligodactyly (hands) (HP:0001180)2.41250210
38Acute myeloid leukemia (HP:0004808)2.40660300
39Prominent nose (HP:0000448)2.38223912
40Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.34663352
41Abnormality of the anterior horn cell (HP:0006802)2.34653781
42Degeneration of anterior horn cells (HP:0002398)2.34653781
43Glioma (HP:0009733)2.34587463
44Increased nuchal translucency (HP:0010880)2.31999993
45Abnormality of the astrocytes (HP:0100707)2.29880757
46Astrocytoma (HP:0009592)2.29880757
47Chronic otitis media (HP:0000389)2.29256883
48B lymphocytopenia (HP:0010976)2.28640188
49Abnormality of B cell number (HP:0010975)2.28640188
50Abnormality of T cells (HP:0002843)2.26447341
51Breast hypoplasia (HP:0003187)2.25856087
52Proximal placement of thumb (HP:0009623)2.25167930
53T lymphocytopenia (HP:0005403)2.24774810
54Bone marrow hypocellularity (HP:0005528)2.24441236
55Amaurosis fugax (HP:0100576)2.24216139
56Duodenal stenosis (HP:0100867)2.22268067
57Small intestinal stenosis (HP:0012848)2.22268067
58Abnormality of the fingertips (HP:0001211)2.20840895
59Patellar aplasia (HP:0006443)2.20724797
60Absent thumb (HP:0009777)2.20536580
61Ependymoma (HP:0002888)2.19109572
62Microvesicular hepatic steatosis (HP:0001414)2.18848471
63Deviation of the thumb (HP:0009603)2.18761511
64Elevated erythrocyte sedimentation rate (HP:0003565)2.16059712
65Recurrent abscess formation (HP:0002722)2.15704535
66Abnormality of abdominal situs (HP:0011620)2.15553797
67Abdominal situs inversus (HP:0003363)2.15553797
68Pancytopenia (HP:0001876)2.14421365
69Neoplasm of the colon (HP:0100273)2.11992620
70Abnormality of T cell number (HP:0011839)2.11928237
71Abnormality of T cell physiology (HP:0011840)2.11895383
72Premature graying of hair (HP:0002216)2.11740177
73Myositis (HP:0100614)2.11311879
74Neoplasm of the pancreas (HP:0002894)2.10754615
75Macrocytic anemia (HP:0001972)2.10418478
76Cellulitis (HP:0100658)2.09879672
77Microglossia (HP:0000171)2.09416845
78Recurrent fungal infections (HP:0002841)2.07380474
79Impulsivity (HP:0100710)2.06079503
80Aplasia/Hypoplasia of the patella (HP:0006498)2.05922656
81Progressive inability to walk (HP:0002505)2.05464857
82Short tibia (HP:0005736)2.05022312
83Rhabdomyosarcoma (HP:0002859)2.04902693
84Petechiae (HP:0000967)2.04488152
8511 pairs of ribs (HP:0000878)2.04436483
86Clubbing of toes (HP:0100760)2.03845942
87Thyroid carcinoma (HP:0002890)2.03252340
88Recurrent bronchitis (HP:0002837)2.02190927
89Abnormality of the carotid arteries (HP:0005344)2.01817738
90Facial hemangioma (HP:0000329)2.01763956
91Papillary thyroid carcinoma (HP:0002895)2.01043963
92IgG deficiency (HP:0004315)2.00927695
93Leukopenia (HP:0001882)1.98880917
94Poikiloderma (HP:0001029)1.98733960
95Bifid tongue (HP:0010297)1.98395551
96Type I transferrin isoform profile (HP:0003642)1.97820286
97Sloping forehead (HP:0000340)1.97623734
98Cutaneous melanoma (HP:0012056)1.96605070
99Supernumerary spleens (HP:0009799)1.96479846
100Microretrognathia (HP:0000308)1.96204017
101High pitched voice (HP:0001620)1.95966465
102Entropion (HP:0000621)1.95787115
103Short middle phalanx of the 5th finger (HP:0004220)1.95663638
104Increased density of long bones (HP:0006392)1.93669952
105IgA deficiency (HP:0002720)1.93456661
106Oligodactyly (HP:0012165)1.93431321
107Panhypogammaglobulinemia (HP:0003139)1.92281580
108Rough bone trabeculation (HP:0100670)1.92043261
109Long eyelashes (HP:0000527)1.91713189
110Postnatal microcephaly (HP:0005484)1.91675217
111Squamous cell carcinoma (HP:0002860)1.91252060
112Short thumb (HP:0009778)1.91097463
113Triphalangeal thumb (HP:0001199)1.90726462
114Abnormal number of incisors (HP:0011064)1.89658392
115Autoimmune hemolytic anemia (HP:0001890)1.87930035
116Aplasia/Hypoplasia of the tibia (HP:0005772)1.87898052
117Recurrent bacterial skin infections (HP:0005406)1.86857881
118Abnormal protein glycosylation (HP:0012346)1.86731739
119Abnormal glycosylation (HP:0012345)1.86731739
120Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.86731739
121Abnormal protein N-linked glycosylation (HP:0012347)1.86731739
122Atresia of the external auditory canal (HP:0000413)1.86592598
123Gonadotropin excess (HP:0000837)1.86163583
124Cholecystitis (HP:0001082)1.86058870
125Abnormal gallbladder physiology (HP:0012438)1.86058870
126Abnormality of cells of the lymphoid lineage (HP:0012140)1.85217485
127Overlapping toe (HP:0001845)1.84881564
128Breast carcinoma (HP:0003002)1.84473850
129Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.84091820
130Short 4th metacarpal (HP:0010044)1.84091820
131Arteriovenous malformation (HP:0100026)1.83655839
132Cafe-au-lait spot (HP:0000957)1.83344391
133Ovarian neoplasm (HP:0100615)1.83140545
134Intestinal atresia (HP:0011100)1.82947370
135Choanal atresia (HP:0000453)1.82881649
136Slender long bone (HP:0003100)1.82800714
137Cellular immunodeficiency (HP:0005374)1.82359995
138Aplasia/Hypoplasia of the sternum (HP:0006714)1.82107014
139Hypoproteinemia (HP:0003075)1.81192860
140Blepharitis (HP:0000498)1.80304648
141Embryonal neoplasm (HP:0002898)1.80165016
142Tracheoesophageal fistula (HP:0002575)1.79800558
143Aplasia/Hypoplasia of the tongue (HP:0010295)1.79509310
144Lymphopenia (HP:0001888)1.79133410
145Biliary tract neoplasm (HP:0100574)1.78355966
146Cutis marmorata (HP:0000965)1.77364495
147Aplasia/Hypoplasia of the earlobes (HP:0009906)1.76573907
148Abnormality of the duodenum (HP:0002246)1.75000093
149Severe combined immunodeficiency (HP:0004430)1.74510109
150Abnormality of reticulocytes (HP:0004312)1.74421496
151Abnormal spermatogenesis (HP:0008669)1.73353115
152Abnormality of the prostate (HP:0008775)1.72941706
153Abnormality of DNA repair (HP:0003254)1.70709180
154Granulocytopenia (HP:0001913)1.70285302
155Duplicated collecting system (HP:0000081)1.69806619
156Combined immunodeficiency (HP:0005387)1.69519059
157Stenosis of the external auditory canal (HP:0000402)1.68448220
158Eosinophilia (HP:0001880)1.66351388
159Central scotoma (HP:0000603)1.66145884
160Preaxial hand polydactyly (HP:0001177)1.66001736
161Astigmatism (HP:0000483)1.64874231
162Clitoromegaly (HP:0000057)1.64360376

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.03545197
2WEE13.44949480
3PBK3.11189815
4NEK22.97486963
5BUB12.81873375
6ACVR1B2.21358779
7NME22.20717242
8EIF2AK12.13756817
9EEF2K2.07664286
10MAP4K12.03925579
11RPS6KA42.02145715
12BRSK21.99558121
13STK101.89537923
14SRPK11.89189368
15CDK121.87646548
16TRIM281.84187411
17TLK11.80378227
18SCYL21.67966288
19MKNK11.67070879
20TTK1.64008730
21ATR1.63941291
22PASK1.62564760
23AURKB1.58322091
24EIF2AK31.50597722
25PLK11.50339339
26PKN21.47894991
27STK41.47774344
28CDK41.47609491
29FLT31.47433834
30RPS6KB21.46584787
31DYRK31.46113490
32CDK71.44072495
33MAP3K101.42468879
34VRK21.40377150
35TSSK61.39427636
36MAP3K81.38426983
37NEK11.35512415
38VRK11.35512066
39ERBB41.33799787
40PLK41.33606603
41PNCK1.32876481
42PIM11.28690452
43TGFBR11.28599511
44TESK21.26764730
45BCR1.26423506
46TEC1.26064173
47STK38L1.24840472
48CHEK21.24218082
49TAF11.24104069
50MKNK21.20310620
51CDK61.18915791
52PDK21.14898438
53TYK21.14524689
54JAK31.12944447
55BTK1.11878196
56LRRK21.09817117
57ZAK1.08844063
58BMPR1B1.03939409
59NEK91.03376313
60CHEK11.03168540
61KIT1.02349882
62PLK31.02239136
63PIM20.99050327
64BRSK10.98184516
65BRD40.98167710
66TXK0.97583106
67CCNB10.95389210
68ZAP700.92885704
69PAK40.91992062
70STK30.91481130
71ERBB30.90619625
72MAP2K30.88840572
73IRAK40.88302922
74CSF1R0.86542621
75ATM0.83386483
76STK390.80034760
77ITK0.79520876
78PLK20.79429397
79AURKA0.70688271
80CLK10.70186124
81MET0.69528618
82CDK20.69334655
83BLK0.68092584
84EIF2AK20.67098434
85IKBKB0.65757892
86STK160.65545127
87EPHA20.64634877
88ALK0.64074727
89RPS6KA50.62963894
90TBK10.62090582
91KDR0.61841519
92GRK60.61500332
93MELK0.60375743
94FGFR10.60217797
95CSNK1G10.59919037
96BRAF0.57686016
97SYK0.57272574
98CDK80.56367757
99CHUK0.56317941
100NEK60.53788380
101CSNK1G30.53754382
102MAP3K140.52572631
103LCK0.51466259
104NUAK10.50832323
105LYN0.50613750
106MAP4K20.48748977
107CSNK1A1L0.48539219
108CDK10.47466055
109RAF10.47010532
110MARK30.46426904
111CSK0.46171730
112CSNK2A20.46011519
113NLK0.45634346
114BMPR20.43258935
115CSNK2A10.43173640
116WNK30.42757649
117MST40.41381208
118YES10.41246998
119CDK90.41078774
120BCKDK0.40851855
121PRKCI0.38975941
122TGFBR20.38937997
123TNIK0.38369158
124LATS10.37675108
125IRAK30.37530527
126TRPM70.37113498
127KSR10.36860423
128IKBKE0.36174295
129WNK40.36071750
130MAPKAPK20.35697393
131PAK10.35601350
132PRKCQ0.33873445
133CSNK1G20.33503999
134NME10.33000059
135MST1R0.31419480
136MAP3K120.27300595
137FRK0.23510183
138EGFR0.21084902

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.91573397
2Mismatch repair_Homo sapiens_hsa034303.94493419
3Base excision repair_Homo sapiens_hsa034102.83115334
4Homologous recombination_Homo sapiens_hsa034402.72611688
5Cell cycle_Homo sapiens_hsa041102.72275431
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.68682125
7Ribosome_Homo sapiens_hsa030102.66350216
8Spliceosome_Homo sapiens_hsa030402.66177617
9RNA transport_Homo sapiens_hsa030132.46521525
10Nucleotide excision repair_Homo sapiens_hsa034202.45539967
11One carbon pool by folate_Homo sapiens_hsa006702.36063179
12Fanconi anemia pathway_Homo sapiens_hsa034602.06103018
13Non-homologous end-joining_Homo sapiens_hsa034502.01761345
14Pyrimidine metabolism_Homo sapiens_hsa002401.89820716
15Protein export_Homo sapiens_hsa030601.88671174
16Systemic lupus erythematosus_Homo sapiens_hsa053221.86186464
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.84668742
18RNA polymerase_Homo sapiens_hsa030201.84401528
19p53 signaling pathway_Homo sapiens_hsa041151.82224570
20Proteasome_Homo sapiens_hsa030501.77402580
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.71147201
22Antigen processing and presentation_Homo sapiens_hsa046121.56870770
23RNA degradation_Homo sapiens_hsa030181.52580520
24Primary immunodeficiency_Homo sapiens_hsa053401.49486830
25Herpes simplex infection_Homo sapiens_hsa051681.44803995
26Viral carcinogenesis_Homo sapiens_hsa052031.40222206
27mRNA surveillance pathway_Homo sapiens_hsa030151.34423248
28Basal transcription factors_Homo sapiens_hsa030221.30117458
29Epstein-Barr virus infection_Homo sapiens_hsa051691.27337199
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.26497595
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.25452606
32Steroid biosynthesis_Homo sapiens_hsa001001.22732539
33Fatty acid elongation_Homo sapiens_hsa000621.22131052
34Measles_Homo sapiens_hsa051621.16611545
35Legionellosis_Homo sapiens_hsa051341.13795217
36Small cell lung cancer_Homo sapiens_hsa052221.07064537
37Propanoate metabolism_Homo sapiens_hsa006401.06845402
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03464710
39HTLV-I infection_Homo sapiens_hsa051661.02937079
40Leishmaniasis_Homo sapiens_hsa051401.02015260
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01066860
42Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96881950
43Hematopoietic cell lineage_Homo sapiens_hsa046400.96663238
44Hepatitis B_Homo sapiens_hsa051610.95905692
45Apoptosis_Homo sapiens_hsa042100.94115494
46B cell receptor signaling pathway_Homo sapiens_hsa046620.93916089
47MicroRNAs in cancer_Homo sapiens_hsa052060.93782459
48NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93545937
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.90844512
50Chronic myeloid leukemia_Homo sapiens_hsa052200.90244352
51Shigellosis_Homo sapiens_hsa051310.88433737
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.88132350
53Intestinal immune network for IgA production_Homo sapiens_hsa046720.85588256
54Purine metabolism_Homo sapiens_hsa002300.84223067
55Pyruvate metabolism_Homo sapiens_hsa006200.78804356
56Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78109235
57Thyroid cancer_Homo sapiens_hsa052160.78029087
58RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.77986287
59Influenza A_Homo sapiens_hsa051640.75967223
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75052837
61Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74457894
62Biosynthesis of amino acids_Homo sapiens_hsa012300.72900963
63Acute myeloid leukemia_Homo sapiens_hsa052210.71658560
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71125260
65Viral myocarditis_Homo sapiens_hsa054160.70397196
66Osteoclast differentiation_Homo sapiens_hsa043800.69707443
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.66774194
68Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65987305
69Toxoplasmosis_Homo sapiens_hsa051450.65604671
70Pentose phosphate pathway_Homo sapiens_hsa000300.65313018
71Colorectal cancer_Homo sapiens_hsa052100.65263311
72T cell receptor signaling pathway_Homo sapiens_hsa046600.64576065
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.64390876
74Alcoholism_Homo sapiens_hsa050340.63554635
75Toll-like receptor signaling pathway_Homo sapiens_hsa046200.62635314
76Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62611299
77Pancreatic cancer_Homo sapiens_hsa052120.62391045
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61263328
79Selenocompound metabolism_Homo sapiens_hsa004500.59897237
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58943905
81Oocyte meiosis_Homo sapiens_hsa041140.58766173
82Leukocyte transendothelial migration_Homo sapiens_hsa046700.58325377
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57575696
84Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.56114905
85Carbon metabolism_Homo sapiens_hsa012000.56104394
86N-Glycan biosynthesis_Homo sapiens_hsa005100.55386407
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55086781
88TNF signaling pathway_Homo sapiens_hsa046680.55052399
89Folate biosynthesis_Homo sapiens_hsa007900.54646560
90Sulfur relay system_Homo sapiens_hsa041220.54392632
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.53634269
92Glutathione metabolism_Homo sapiens_hsa004800.51893551
93Allograft rejection_Homo sapiens_hsa053300.50434701
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.49284942
95Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.47958744
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47925415
97Vitamin B6 metabolism_Homo sapiens_hsa007500.46435251
98Prostate cancer_Homo sapiens_hsa052150.44517424
99Malaria_Homo sapiens_hsa051440.44359715
100Notch signaling pathway_Homo sapiens_hsa043300.43954877
101Asthma_Homo sapiens_hsa053100.43896114
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43692039
103Non-small cell lung cancer_Homo sapiens_hsa052230.43634982
104Tuberculosis_Homo sapiens_hsa051520.43435731
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43307828
106Renin-angiotensin system_Homo sapiens_hsa046140.40733575
107Pertussis_Homo sapiens_hsa051330.40503568
108Platelet activation_Homo sapiens_hsa046110.39776755
1092-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39322259
110Bladder cancer_Homo sapiens_hsa052190.39234341
111Huntingtons disease_Homo sapiens_hsa050160.38678678
112Cysteine and methionine metabolism_Homo sapiens_hsa002700.38019296
113Fatty acid metabolism_Homo sapiens_hsa012120.37641786
114Pathways in cancer_Homo sapiens_hsa052000.36900794
115HIF-1 signaling pathway_Homo sapiens_hsa040660.36205828
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36058637
117Adherens junction_Homo sapiens_hsa045200.36012451
118Metabolic pathways_Homo sapiens_hsa011000.34842337
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.32794653
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.32278010
121TGF-beta signaling pathway_Homo sapiens_hsa043500.31740218
122Cyanoamino acid metabolism_Homo sapiens_hsa004600.31180035
123Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.30269912
124Salmonella infection_Homo sapiens_hsa051320.30100174
125Caffeine metabolism_Homo sapiens_hsa002320.29100573
126Parkinsons disease_Homo sapiens_hsa050120.28430608
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.26259257
128Regulation of autophagy_Homo sapiens_hsa041400.25601379
129Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.24293046
130Lysine degradation_Homo sapiens_hsa003100.23125245
131Peroxisome_Homo sapiens_hsa041460.21974086
132Hippo signaling pathway_Homo sapiens_hsa043900.21526552
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.19651605
134Phototransduction_Homo sapiens_hsa047440.18790671
135Melanoma_Homo sapiens_hsa052180.15058418
136Rheumatoid arthritis_Homo sapiens_hsa053230.15041815
137Sulfur metabolism_Homo sapiens_hsa009200.13270736

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