ERI2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.29101026
2CENP-A containing nucleosome assembly (GO:0034080)5.13487090
3chromatin remodeling at centromere (GO:0031055)5.04300743
4kinetochore organization (GO:0051383)5.03852014
5metaphase plate congression (GO:0051310)4.84309631
6kinetochore assembly (GO:0051382)4.62261588
7DNA replication initiation (GO:0006270)4.60185890
8attachment of spindle microtubules to kinetochore (GO:0008608)4.46658230
9protein localization to kinetochore (GO:0034501)4.43441482
10DNA replication-independent nucleosome organization (GO:0034724)4.35331091
11DNA replication-independent nucleosome assembly (GO:0006336)4.35331091
12meiotic chromosome segregation (GO:0045132)4.30844836
13histone exchange (GO:0043486)4.28194344
14establishment of chromosome localization (GO:0051303)4.18691358
15telomere maintenance via semi-conservative replication (GO:0032201)4.11268400
16DNA replication checkpoint (GO:0000076)4.10401409
17protein localization to chromosome, centromeric region (GO:0071459)4.07786264
18mitotic sister chromatid segregation (GO:0000070)4.06293351
19sister chromatid segregation (GO:0000819)3.96636682
20DNA strand elongation involved in DNA replication (GO:0006271)3.96062006
21DNA strand elongation (GO:0022616)3.91062946
22mitotic recombination (GO:0006312)3.87041436
23nucleotide-excision repair, DNA gap filling (GO:0006297)3.85870766
24microtubule depolymerization (GO:0007019)3.85568544
25telomere maintenance via recombination (GO:0000722)3.85556647
26nuclear pore organization (GO:0006999)3.85154789
27DNA synthesis involved in DNA repair (GO:0000731)3.84543963
28mitotic chromosome condensation (GO:0007076)3.74179373
29spindle checkpoint (GO:0031577)3.72114571
30negative regulation of DNA-dependent DNA replication (GO:2000104)3.72059212
31nuclear pore complex assembly (GO:0051292)3.66794997
32telomere maintenance via telomere lengthening (GO:0010833)3.64479585
33spindle assembly checkpoint (GO:0071173)3.62643194
34double-strand break repair via nonhomologous end joining (GO:0006303)3.61958700
35non-recombinational repair (GO:0000726)3.61958700
36negative regulation of mitotic sister chromatid separation (GO:2000816)3.58422335
37negative regulation of mitotic sister chromatid segregation (GO:0033048)3.58422335
38negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.58422335
39negative regulation of sister chromatid segregation (GO:0033046)3.58422335
40regulation of centriole replication (GO:0046599)3.57070455
41negative regulation of chromosome segregation (GO:0051985)3.52824613
42DNA unwinding involved in DNA replication (GO:0006268)3.52136538
43regulation of nuclear cell cycle DNA replication (GO:0033262)3.51684337
44regulation of DNA endoreduplication (GO:0032875)3.51164018
45mitotic spindle assembly checkpoint (GO:0007094)3.50690894
46negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.48750105
47mitotic spindle checkpoint (GO:0071174)3.46187527
48synapsis (GO:0007129)3.45578098
49regulation of mitotic metaphase/anaphase transition (GO:0030071)3.44715379
50DNA topological change (GO:0006265)3.43434571
51positive regulation of mitotic sister chromatid separation (GO:1901970)3.40120383
52positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.40120383
53positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.40120383
54protein K6-linked ubiquitination (GO:0085020)3.39974330
55regulation of centrosome cycle (GO:0046605)3.39972762
56intra-S DNA damage checkpoint (GO:0031573)3.39513555
57DNA double-strand break processing (GO:0000729)3.39053358
58DNA replication-dependent nucleosome assembly (GO:0006335)3.38210244
59DNA replication-dependent nucleosome organization (GO:0034723)3.38210244
60regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.37552904
61chromosome segregation (GO:0007059)3.35274025
62somatic hypermutation of immunoglobulin genes (GO:0016446)3.35235153
63somatic diversification of immune receptors via somatic mutation (GO:0002566)3.35235153
64transcription-coupled nucleotide-excision repair (GO:0006283)3.34782592
65mitotic nuclear envelope disassembly (GO:0007077)3.34393801
66regulation of spindle organization (GO:0090224)3.34235787
67regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.34182945
68DNA ligation (GO:0006266)3.33101567
69regulation of sister chromatid cohesion (GO:0007063)3.33075991
70regulation of mitotic sister chromatid separation (GO:0010965)3.32237951
71regulation of mitotic sister chromatid segregation (GO:0033047)3.32237951
72regulation of sister chromatid segregation (GO:0033045)3.32237951
73gonadal mesoderm development (GO:0007506)3.30874838
74regulation of chromosome segregation (GO:0051983)3.30685102
75folic acid-containing compound biosynthetic process (GO:0009396)3.29402207
76rRNA modification (GO:0000154)3.28852705
77ATP-dependent chromatin remodeling (GO:0043044)3.27130744
78regulation of centrosome duplication (GO:0010824)3.24994894
79regulation of helicase activity (GO:0051095)3.22293648
80regulation of double-strand break repair via homologous recombination (GO:0010569)3.22035484
81maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.20512660
82nucleobase biosynthetic process (GO:0046112)3.18877128
83maturation of SSU-rRNA (GO:0030490)3.18055066
84mismatch repair (GO:0006298)3.17619856
85purine nucleobase biosynthetic process (GO:0009113)3.16541044
86centriole replication (GO:0007099)3.10864592
87negative regulation of DNA recombination (GO:0045910)3.10475055
88ribosome biogenesis (GO:0042254)3.09198691
89telomere maintenance (GO:0000723)3.08822809
90telomere organization (GO:0032200)3.08643358
91regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.07077648
92pore complex assembly (GO:0046931)3.06172354
93chromosome condensation (GO:0030261)3.04523713
94chromatin assembly or disassembly (GO:0006333)3.02255821
95spliceosomal snRNP assembly (GO:0000387)3.01148955
96resolution of meiotic recombination intermediates (GO:0000712)3.00352412
97protein localization to chromosome (GO:0034502)3.00117912
98membrane disassembly (GO:0030397)3.00088403
99nuclear envelope disassembly (GO:0051081)3.00088403
100mitotic sister chromatid cohesion (GO:0007064)2.99529934
101negative regulation of mitosis (GO:0045839)2.99198299
102postreplication repair (GO:0006301)2.98053778
103replication fork processing (GO:0031297)2.98038869
104establishment of integrated proviral latency (GO:0075713)2.97700091
105maturation of 5.8S rRNA (GO:0000460)2.97056033
106RNA capping (GO:0036260)2.96425891
1077-methylguanosine RNA capping (GO:0009452)2.96425891
108rRNA methylation (GO:0031167)2.96193410
109positive regulation of chromosome segregation (GO:0051984)2.93512010
110proteasome assembly (GO:0043248)2.92158076
111DNA strand renaturation (GO:0000733)2.91645272
112deoxyribonucleotide biosynthetic process (GO:0009263)2.91540829
113ribosome assembly (GO:0042255)2.90536956
114regulation of translational fidelity (GO:0006450)2.89483152
115transcription elongation from RNA polymerase I promoter (GO:0006362)2.87745172
116DNA replication (GO:0006260)2.87444373
117DNA catabolic process, exonucleolytic (GO:0000738)2.87440994
118regulation of mitotic spindle organization (GO:0060236)2.86870101
1197-methylguanosine mRNA capping (GO:0006370)2.86565508
120DNA-dependent DNA replication (GO:0006261)2.86259173
121sister chromatid cohesion (GO:0007062)2.84668325
122DNA packaging (GO:0006323)2.83041272
123mitotic cell cycle (GO:0000278)2.81976598
124translesion synthesis (GO:0019985)2.79319830
125DNA conformation change (GO:0071103)2.75372834
126mitotic G2/M transition checkpoint (GO:0044818)2.72883621

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.94798959
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.37298113
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.69337897
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.84036742
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.69389281
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.40811447
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.28449297
8RBPJ_22232070_ChIP-Seq_NCS_Mouse3.27845474
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.03279176
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.85914798
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.83436277
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.71069413
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.59476244
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53525305
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.46841812
16* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.44163580
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.41503347
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.39227805
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.36894392
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.35646510
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34519262
22MYC_18358816_ChIP-ChIP_MESCs_Mouse2.29176233
23AR_21909140_ChIP-Seq_LNCAP_Human2.27374180
24E2F1_21310950_ChIP-Seq_MCF-7_Human2.16132346
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.15983945
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.15916088
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14775593
28VDR_23849224_ChIP-Seq_CD4+_Human2.14761203
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.13599606
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.13346703
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.10960846
32ELK1_19687146_ChIP-ChIP_HELA_Human2.03832234
33FOXP3_21729870_ChIP-Seq_TREG_Human1.94664912
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.90603036
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89893471
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.89495750
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.86758218
38* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81041286
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.80141771
40XRN2_22483619_ChIP-Seq_HELA_Human1.78921416
41TTF2_22483619_ChIP-Seq_HELA_Human1.71626322
42DCP1A_22483619_ChIP-Seq_HELA_Human1.70564599
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.67598491
44PADI4_21655091_ChIP-ChIP_MCF-7_Human1.63572113
45E2F1_18555785_ChIP-Seq_MESCs_Mouse1.62554808
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57575399
47NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.55668256
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.51795296
49GABP_19822575_ChIP-Seq_HepG2_Human1.50354867
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45789161
51SRF_21415370_ChIP-Seq_HL-1_Mouse1.45698655
52FUS_26573619_Chip-Seq_HEK293_Human1.45473554
53SOX2_18555785_ChIP-Seq_MESCs_Mouse1.45139937
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.40728421
55EWS_26573619_Chip-Seq_HEK293_Human1.36239486
56GATA1_22025678_ChIP-Seq_K562_Human1.34368527
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.34307535
58NANOG_18555785_ChIP-Seq_MESCs_Mouse1.33337143
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.26581397
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23545622
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.23339079
62MYC_18940864_ChIP-ChIP_HL60_Human1.20864278
63SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17608911
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.17459251
65POU5F1_16153702_ChIP-ChIP_HESCs_Human1.13404838
66ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12807041
67RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11771045
68HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.11171381
69EGR1_19374776_ChIP-ChIP_THP-1_Human1.11066799
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08306893
71FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07460121
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06974126
73CIITA_25753668_ChIP-Seq_RAJI_Human1.06503284
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.04891050
75ZFX_18555785_ChIP-Seq_MESCs_Mouse1.04779784
76TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.04079705
77KDM5A_27292631_Chip-Seq_BREAST_Human1.02353789
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02241845
79BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.97339431
80TFEB_21752829_ChIP-Seq_HELA_Human0.96716292
81CHD1_26751641_Chip-Seq_LNCaP_Human0.96452354
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.95617261
83SOX2_16153702_ChIP-ChIP_HESCs_Human0.95084026
84PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94665059
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.92856179
86CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.91856806
87SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.91122729
88IRF1_19129219_ChIP-ChIP_H3396_Human0.89688725
89WT1_19549856_ChIP-ChIP_CCG9911_Human0.88185722
90TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.87220089
91PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87218412
92FOXM1_26456572_ChIP-Seq_MCF-7_Human0.87130051
93HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.87030856
94TAF15_26573619_Chip-Seq_HEK293_Human0.85870935
95NFE2_27457419_Chip-Seq_LIVER_Mouse0.85062891
96SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.84752198
97CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83149340
98CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82594752
99CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.82472339
100FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.81930946
101KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.81533170
102CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.81472969
103NANOG_16153702_ChIP-ChIP_HESCs_Human0.80298522
104FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.79174590
105FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.78543554
106FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.78519384
107GATA1_26923725_Chip-Seq_HPCs_Mouse0.77464659
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.76203383
109KAP1_22055183_ChIP-Seq_ESCs_Mouse0.75993168
110SUZ12_27294783_Chip-Seq_NPCs_Mouse0.75957503
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75618355
112SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.74820015
113GATA4_21415370_ChIP-Seq_HL-1_Mouse0.74096067
114ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.74021518
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.72051814
116ER_23166858_ChIP-Seq_MCF-7_Human0.71167594
117IGF1R_20145208_ChIP-Seq_DFB_Human0.71034693
118PKCTHETA_26484144_Chip-Seq_BREAST_Human0.70578099
119KLF4_18555785_ChIP-Seq_MESCs_Mouse0.70019553
120CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.69546271
121ZNF263_19887448_ChIP-Seq_K562_Human0.69183818
122NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.69082977
123DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.67983767
124AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.67706691
125POU3F2_20337985_ChIP-ChIP_501MEL_Human0.67492763

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.01515145
2MP0008058_abnormal_DNA_repair4.44465898
3MP0003111_abnormal_nucleus_morphology4.34838286
4MP0003693_abnormal_embryo_hatching4.34752768
5MP0008057_abnormal_DNA_replication4.10799522
6MP0003077_abnormal_cell_cycle3.61927965
7MP0004957_abnormal_blastocyst_morpholog3.35992336
8MP0006292_abnormal_olfactory_placode2.95863379
9MP0008877_abnormal_DNA_methylation2.95310784
10MP0008007_abnormal_cellular_replicative2.87226606
11MP0008932_abnormal_embryonic_tissue2.52930763
12MP0004147_increased_porphyrin_level2.46325305
13MP0000566_synostosis2.39830977
14MP0003123_paternal_imprinting2.21079478
15MP0002009_preneoplasia2.16179170
16MP0003786_premature_aging2.09309358
17MP0010352_gastrointestinal_tract_polyps2.01682531
18MP0003718_maternal_effect1.99206347
19MP0001188_hyperpigmentation1.90445979
20MP0003890_abnormal_embryonic-extraembry1.89636171
21MP0003121_genomic_imprinting1.86502418
22MP0003656_abnormal_erythrocyte_physiolo1.83183355
23MP0002210_abnormal_sex_determination1.79957901
24MP0010234_abnormal_vibrissa_follicle1.79352953
25MP0002396_abnormal_hematopoietic_system1.77901439
26MP0009379_abnormal_foot_pigmentation1.75323428
27MP0009697_abnormal_copulation1.73004989
28MP0002160_abnormal_reproductive_system1.66078834
29MP0003941_abnormal_skin_development1.65730277
30MP0001730_embryonic_growth_arrest1.57750734
31MP0000350_abnormal_cell_proliferation1.54452304
32MP0003315_abnormal_perineum_morphology1.51062842
33MP0001929_abnormal_gametogenesis1.48701427
34MP0003787_abnormal_imprinting1.47659092
35MP0001145_abnormal_male_reproductive1.46924584
36MP0008789_abnormal_olfactory_epithelium1.45516340
37MP0005389_reproductive_system_phenotype1.40628004
38MP0003136_yellow_coat_color1.39711083
39MP0000653_abnormal_sex_gland1.39388975
40MP0002102_abnormal_ear_morphology1.37775842
41MP0003937_abnormal_limbs/digits/tail_de1.37719087
42MP0002938_white_spotting1.36462075
43MP0002877_abnormal_melanocyte_morpholog1.33434376
44MP0001293_anophthalmia1.31924525
45MP0004264_abnormal_extraembryonic_tissu1.31600361
46MP0005380_embryogenesis_phenotype1.30970289
47MP0001672_abnormal_embryogenesis/_devel1.30970289
48MP0001697_abnormal_embryo_size1.29633201
49MP0002085_abnormal_embryonic_tissue1.28978026
50MP0010030_abnormal_orbit_morphology1.27021030
51MP0010678_abnormal_skin_adnexa1.23823053
52MP0001119_abnormal_female_reproductive1.23042839
53MP0002084_abnormal_developmental_patter1.19985241
54MP0000313_abnormal_cell_death1.16660913
55MP0004133_heterotaxia1.15583367
56MP0010307_abnormal_tumor_latency1.13331492
57MP0002132_abnormal_respiratory_system1.12898019
58MP0002139_abnormal_hepatobiliary_system1.12457149
59MP0006072_abnormal_retinal_apoptosis1.10703114
60MP0001529_abnormal_vocalization1.10558167
61MP0002234_abnormal_pharynx_morphology1.09601749
62MP0003984_embryonic_growth_retardation1.08497466
63MP0000358_abnormal_cell_content/1.07173907
64MP0005085_abnormal_gallbladder_physiolo1.06691620
65MP0002697_abnormal_eye_size1.05837964
66MP0002095_abnormal_skin_pigmentation1.05792992
67MP0002088_abnormal_embryonic_growth/wei1.04777370
68MP0001286_abnormal_eye_development1.03608553
69MP0002080_prenatal_lethality1.03574891
70MP0003698_abnormal_male_reproductive1.03270829
71MP0000049_abnormal_middle_ear1.01083233
72MP0001881_abnormal_mammary_gland1.00496215
73MP0003938_abnormal_ear_development0.99272161
74MP0005646_abnormal_pituitary_gland0.96155174
75MP0001346_abnormal_lacrimal_gland0.94918424
76MP0001666_abnormal_nutrient_absorption0.94758617
77MP0003186_abnormal_redox_activity0.93180251
78MP0000490_abnormal_crypts_of0.93059277
79MP0000647_abnormal_sebaceous_gland0.92934447
80MP0005394_taste/olfaction_phenotype0.92242306
81MP0005499_abnormal_olfactory_system0.92242306
82MP0002249_abnormal_larynx_morphology0.91993661
83MP0005248_abnormal_Harderian_gland0.91650201
84MP0005171_absent_coat_pigmentation0.91441040
85MP0003950_abnormal_plasma_membrane0.89913405
86MP0002233_abnormal_nose_morphology0.89882916
87MP0005187_abnormal_penis_morphology0.89706354
88MP0006035_abnormal_mitochondrial_morpho0.89420949
89MP0005220_abnormal_exocrine_pancreas0.89306385
90MP0003755_abnormal_palate_morphology0.87963626
91MP0004197_abnormal_fetal_growth/weight/0.87763348
92MP0004381_abnormal_hair_follicle0.87044490
93MP0004808_abnormal_hematopoietic_stem0.86673857
94MP0001661_extended_life_span0.86623371
95MP0002111_abnormal_tail_morphology0.86546844
96MP0000678_abnormal_parathyroid_gland0.86441970
97MP0006036_abnormal_mitochondrial_physio0.86070376
98MP0003763_abnormal_thymus_physiology0.85213717
99MP0002019_abnormal_tumor_incidence0.84989857
100MP0000427_abnormal_hair_cycle0.84126664
101MP0001919_abnormal_reproductive_system0.83898440
102MP0005408_hypopigmentation0.83343636
103MP0000383_abnormal_hair_follicle0.83231572
104MP0002086_abnormal_extraembryonic_tissu0.82814038
105MP0005075_abnormal_melanosome_morpholog0.81932935
106MP0005647_abnormal_sex_gland0.81450190
107MP0002277_abnormal_respiratory_mucosa0.79697988
108MP0005395_other_phenotype0.79343009
109MP0000428_abnormal_craniofacial_morphol0.78635628
110MP0003806_abnormal_nucleotide_metabolis0.77725018
111MP0000015_abnormal_ear_pigmentation0.77158340
112MP0003943_abnormal_hepatobiliary_system0.76035978
113MP0004233_abnormal_muscle_weight0.76002405
114MP0005365_abnormal_bile_salt0.75950118
115MP0003936_abnormal_reproductive_system0.74649764
116MP0005076_abnormal_cell_differentiation0.74588124
117MP0000703_abnormal_thymus_morphology0.74481053
118MP0002092_abnormal_eye_morphology0.74436785
119MP0009703_decreased_birth_body0.74344231
120MP0003119_abnormal_digestive_system0.73672329
121MP0005409_darkened_coat_color0.73453090
122MP0003567_abnormal_fetal_cardiomyocyte0.73000381
123MP0000432_abnormal_head_morphology0.72368618
124MP0001727_abnormal_embryo_implantation0.71935730
125MP0001186_pigmentation_phenotype0.71790121
126MP0003942_abnormal_urinary_system0.71498882
127MP0009672_abnormal_birth_weight0.71144359
128MP0005501_abnormal_skin_physiology0.71099671
129MP0008004_abnormal_stomach_pH0.70623615
130MP0003861_abnormal_nervous_system0.70441909
131MP0003868_abnormal_feces_composition0.70318701
132MP0008995_early_reproductive_senescence0.70047995
133MP0005384_cellular_phenotype0.69727052
134MP0003221_abnormal_cardiomyocyte_apopto0.68748517
135MP0002751_abnormal_autonomic_nervous0.68717202
136MP0002098_abnormal_vibrissa_morphology0.68680529
137MP0005174_abnormal_tail_pigmentation0.68573381
138MP0002161_abnormal_fertility/fecundity0.68477945
139MP0001764_abnormal_homeostasis0.67102352
140MP0004185_abnormal_adipocyte_glucose0.66802766
141MP0002114_abnormal_axial_skeleton0.66420623
142MP0000627_abnormal_mammary_gland0.66347152
143MP0003699_abnormal_female_reproductive0.65639816
144MP0003935_abnormal_craniofacial_develop0.64948365

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)6.01416795
2Chromsome breakage (HP:0040012)5.96480771
3Birth length less than 3rd percentile (HP:0003561)3.97491716
4Abnormality of chromosome stability (HP:0003220)3.48947332
5Abnormality of the preputium (HP:0100587)3.42136133
6Supernumerary spleens (HP:0009799)3.41239575
7Meckel diverticulum (HP:0002245)3.37941506
8Increased serum pyruvate (HP:0003542)3.31331255
9Rhabdomyosarcoma (HP:0002859)3.31044937
10Oral leukoplakia (HP:0002745)3.22418468
11Abnormality of glycolysis (HP:0004366)3.18195706
12Abnormality of the ileum (HP:0001549)3.14423038
13Breast hypoplasia (HP:0003187)3.09577505
14Pancreatic fibrosis (HP:0100732)3.08718173
15Impulsivity (HP:0100710)3.05138432
16Reticulocytopenia (HP:0001896)3.02825163
17Aplasia/Hypoplasia of the uvula (HP:0010293)3.00065403
18Duplicated collecting system (HP:0000081)2.96272782
19Pancreatic cysts (HP:0001737)2.87401739
20Colon cancer (HP:0003003)2.85221186
21Glioma (HP:0009733)2.82327665
22Abnormality of the renal collecting system (HP:0004742)2.80541024
23Abnormal lung lobation (HP:0002101)2.79000307
24Abnormality of the astrocytes (HP:0100707)2.76209941
25Astrocytoma (HP:0009592)2.76209941
26Cortical dysplasia (HP:0002539)2.75686898
27True hermaphroditism (HP:0010459)2.72454598
2811 pairs of ribs (HP:0000878)2.71212080
29Abnormal respiratory motile cilium physiology (HP:0012261)2.70323245
30Abnormal spermatogenesis (HP:0008669)2.69757522
31Small intestinal stenosis (HP:0012848)2.68858699
32Duodenal stenosis (HP:0100867)2.68858699
33Abnormal ciliary motility (HP:0012262)2.68807972
34Patellar aplasia (HP:0006443)2.65922655
35Abnormality of DNA repair (HP:0003254)2.65229422
36Ependymoma (HP:0002888)2.62277954
37Papillary thyroid carcinoma (HP:0002895)2.62055205
38Ectopic kidney (HP:0000086)2.61225305
39Bone marrow hypocellularity (HP:0005528)2.58849705
40Nephroblastoma (Wilms tumor) (HP:0002667)2.57333442
41Sloping forehead (HP:0000340)2.55625896
42Absent radius (HP:0003974)2.49524994
43Embryonal renal neoplasm (HP:0011794)2.48693403
44Aplasia/Hypoplasia of the patella (HP:0006498)2.48338909
45Rough bone trabeculation (HP:0100670)2.47960737
46Medulloblastoma (HP:0002885)2.46609706
47Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.44503335
48Abnormality of the carotid arteries (HP:0005344)2.42733914
49Myelodysplasia (HP:0002863)2.41890143
50Microvesicular hepatic steatosis (HP:0001414)2.40658346
51Premature graying of hair (HP:0002216)2.40190482
52Abnormality of the labia minora (HP:0012880)2.38336822
53Abnormal respiratory motile cilium morphology (HP:0005938)2.33781260
54Abnormal respiratory epithelium morphology (HP:0012253)2.33781260
55Absent forearm bone (HP:0003953)2.33445884
56Aplasia involving forearm bones (HP:0009822)2.33445884
57Asplenia (HP:0001746)2.28469240
58Breast carcinoma (HP:0003002)2.27905904
59Cafe-au-lait spot (HP:0000957)2.26885805
60Ovarian neoplasm (HP:0100615)2.26113253
61Occipital encephalocele (HP:0002085)2.25318262
62Postaxial foot polydactyly (HP:0001830)2.24279914
63Azoospermia (HP:0000027)2.23744638
64Acanthocytosis (HP:0001927)2.22160269
65Triphalangeal thumb (HP:0001199)2.20470523
66Abnormality of the duodenum (HP:0002246)2.20029128
67Hyperglycinuria (HP:0003108)2.19183757
68Microglossia (HP:0000171)2.16053916
69Biliary tract neoplasm (HP:0100574)2.14322823
70Neoplasm of striated muscle (HP:0009728)2.13921091
71Abnormality of chromosome segregation (HP:0002916)2.11944399
72Facial cleft (HP:0002006)2.10838674
73Aplasia/Hypoplasia of the spleen (HP:0010451)2.10750063
74Neoplasm of the small intestine (HP:0100833)2.09827305
75Pheochromocytoma (HP:0002666)2.08808552
76Poikilocytosis (HP:0004447)2.08541380
77Abnormal number of incisors (HP:0011064)2.07979400
78Preaxial hand polydactyly (HP:0001177)2.06155302
79Multiple enchondromatosis (HP:0005701)2.05433290
80Overlapping toe (HP:0001845)2.05254191
81Abnormality of glycine metabolism (HP:0010895)2.04245875
82Abnormality of serine family amino acid metabolism (HP:0010894)2.04245875
83Increased nuchal translucency (HP:0010880)2.04052779
84Selective tooth agenesis (HP:0001592)2.03434003
85Male pseudohermaphroditism (HP:0000037)2.02622271
86Carpal bone hypoplasia (HP:0001498)2.02442681
87Volvulus (HP:0002580)2.01609691
88Thyroid carcinoma (HP:0002890)2.01347941
89Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.01192284
90Short 4th metacarpal (HP:0010044)2.01192284
91Male infertility (HP:0003251)1.99802831
92Aplasia/Hypoplasia of the tongue (HP:0010295)1.98174806
93Horseshoe kidney (HP:0000085)1.97958842
94Tubulointerstitial nephritis (HP:0001970)1.96157345
95Clubbing of toes (HP:0100760)1.95618474
96Adrenal hypoplasia (HP:0000835)1.95575767
97Chronic hepatic failure (HP:0100626)1.95502593
98Short thumb (HP:0009778)1.94341530
99Abnormal biliary tract physiology (HP:0012439)1.94271306
100Bile duct proliferation (HP:0001408)1.94271306
101Arteriovenous malformation (HP:0100026)1.92727461
102Neuroendocrine neoplasm (HP:0100634)1.92267150
103Rhinitis (HP:0012384)1.91969509
104Hyperglycinemia (HP:0002154)1.91051250
105Proximal tubulopathy (HP:0000114)1.90490436
106Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89207754
107Abnormality of alanine metabolism (HP:0010916)1.89207754
108Hyperalaninemia (HP:0003348)1.89207754
109Abnormal trabecular bone morphology (HP:0100671)1.88849377
110Cellular immunodeficiency (HP:0005374)1.86968997
111Hypobetalipoproteinemia (HP:0003563)1.86573653
112Abnormality of methionine metabolism (HP:0010901)1.85687223
113Choanal atresia (HP:0000453)1.85380334
114Neoplasm of the pancreas (HP:0002894)1.84371192
115Tracheoesophageal fistula (HP:0002575)1.83334755
116Absent thumb (HP:0009777)1.82756982
117Duplication of thumb phalanx (HP:0009942)1.80702927
118Uterine neoplasm (HP:0010784)1.80564653
119Molar tooth sign on MRI (HP:0002419)1.78789788
120Abnormality of midbrain morphology (HP:0002418)1.78789788
121Deep philtrum (HP:0002002)1.78166981
122Hypoglycemic coma (HP:0001325)1.77747508
123Aplastic anemia (HP:0001915)1.77671422
124Renal cortical cysts (HP:0000803)1.76852652
125Neoplasm of the rectum (HP:0100743)1.75951280
126Pancreatic islet-cell hyperplasia (HP:0004510)1.75390698
127Intrahepatic cholestasis (HP:0001406)1.75370513
128Facial hemangioma (HP:0000329)1.74865975
129Neoplasm of the colon (HP:0100273)1.74750635
130Aplasia/Hypoplasia of the earlobes (HP:0009906)1.74513490
131Aplasia/Hypoplasia of the sternum (HP:0006714)1.74299371
132Gastrointestinal carcinoma (HP:0002672)1.74241168
133Malignant gastrointestinal tract tumors (HP:0006749)1.74241168
134Medial flaring of the eyebrow (HP:0010747)1.73366566
135Acute myeloid leukemia (HP:0004808)1.73319826
136Short middle phalanx of the 5th finger (HP:0004220)1.71828203
137Natal tooth (HP:0000695)1.71282116
138Neoplasm of the oral cavity (HP:0100649)1.70435800
139Septate vagina (HP:0001153)1.68844965
140Agnosia (HP:0010524)1.68562146
141Limb hypertonia (HP:0002509)1.68178658
142Ureteral duplication (HP:0000073)1.67104591
143Median cleft lip (HP:0000161)1.67021641
144Embryonal neoplasm (HP:0002898)1.63812844
145Cerebral hypomyelination (HP:0006808)1.63771094
146Squamous cell carcinoma (HP:0002860)1.63580090
147Abnormality of serum amino acid levels (HP:0003112)1.63563047
148Optic nerve coloboma (HP:0000588)1.63385975
149Congenital primary aphakia (HP:0007707)1.62822933
150Capillary hemangiomas (HP:0005306)1.61967230
151Abnormality of the anterior horn cell (HP:0006802)1.61923934
152Degeneration of anterior horn cells (HP:0002398)1.61923934
153Urethral obstruction (HP:0000796)1.61677841
154Abnormal biliary tract morphology (HP:0012440)1.61145155
155Progressive external ophthalmoplegia (HP:0000590)1.61023499
156Anencephaly (HP:0002323)1.60756575
157Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.57856415
158Freckling (HP:0001480)1.57254399

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SRPK14.49241543
2BUB13.97409396
3CDC73.70632250
4WEE13.39016129
5PLK43.29956997
6EIF2AK13.27691410
7STK163.02014664
8ZAK2.80510764
9BRSK22.79780143
10TTK2.63830662
11ACVR1B2.59554741
12NEK22.52917689
13SCYL22.17412723
14PLK12.06338197
15TLK12.00203516
16PLK31.98494111
17MST41.89760414
18BRSK11.85125686
19MKNK11.83247763
20ATR1.77456201
21VRK11.75106706
22TRIM281.70031169
23TSSK61.68313078
24CHEK21.67380145
25MKNK21.64540694
26ERBB31.58337244
27AURKB1.55398104
28CCNB11.51783416
29EIF2AK31.43383494
30PASK1.42678568
31PNCK1.38198113
32CASK1.30780674
33TAF11.27530308
34BRD41.26401055
35CDK71.25709840
36LATS11.24372611
37STK38L1.23562343
38CDK121.22693214
39NUAK11.20645807
40CHEK11.17655338
41AURKA1.16716166
42EIF2AK21.13514376
43NEK61.12962310
44TXK1.12735705
45DYRK31.11616427
46AKT31.10404557
47NEK91.03275186
48ATM1.00904868
49PBK1.00868386
50MET0.99200914
51IRAK30.97290085
52NEK10.94071423
53STK30.93685088
54CDK40.87343789
55STK40.84082622
56PINK10.82781094
57TNIK0.82140218
58MST1R0.77944568
59CAMK1G0.77183753
60RPS6KB20.77065540
61MAP2K70.75061140
62CDK20.74781432
63EPHA20.74461570
64CDK10.74404036
65FRK0.74239052
66PDK20.71621612
67VRK20.70218262
68STK390.67891115
69MAPKAPK50.65554070
70EEF2K0.65135949
71CDK60.64407809
72GRK10.63863817
73MELK0.63024371
74BCR0.62639718
75BRAF0.61797326
76CAMK1D0.60965949
77STK240.60883827
78KSR10.60346668
79IRAK40.58052115
80YES10.55548655
81CSNK2A10.55312008
82PLK20.54316922
83BMPR20.52744778
84PRKCI0.51816577
85RAF10.50861310
86CSNK2A20.48980497
87FGFR10.48559060
88STK100.47541272
89MAP3K40.47262554
90CDK90.47074383
91RPS6KA40.46464774
92NME10.45876941
93CDK30.44982495
94PKN20.44324851
95MAP2K60.43698379
96CDK80.43456044
97MAP3K120.43080163
98CSNK1A1L0.40097068
99MAP3K80.37988359
100PRKDC0.37123734
101AKT20.36941178
102CSNK1E0.36809372
103RPS6KA50.36411436
104FER0.36333269
105MAPK130.35174088
106CSNK1G30.32252383
107MAPK140.32105186
108PIK3CA0.30943996
109TESK20.30534884
110CLK10.30349182
111PIM10.27796643
112NME20.27518679
113CSNK1G10.25165575
114PAK40.24769456
115CDC42BPA0.24659479
116GSK3B0.24218295
117WNK30.23275701
118ERBB40.22847026
119NTRK30.22442680
120TRPM70.22220395
121BMPR1B0.22205749
122MAPK70.20846693
123TGFBR10.20190820
124SIK30.19979005
125DYRK20.19606630
126MAP3K60.17924918
127AKT10.16869542
128RPS6KB10.16351812

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.62121544
2Mismatch repair_Homo sapiens_hsa034304.36193754
3Homologous recombination_Homo sapiens_hsa034403.79839833
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.65659039
5Fanconi anemia pathway_Homo sapiens_hsa034603.60750883
6RNA polymerase_Homo sapiens_hsa030203.45569434
7Base excision repair_Homo sapiens_hsa034103.22297425
8Nucleotide excision repair_Homo sapiens_hsa034203.16398946
9Cell cycle_Homo sapiens_hsa041103.11147790
10Spliceosome_Homo sapiens_hsa030402.96298073
11RNA transport_Homo sapiens_hsa030132.87294542
12Pyrimidine metabolism_Homo sapiens_hsa002402.77117612
13One carbon pool by folate_Homo sapiens_hsa006702.55809817
14Non-homologous end-joining_Homo sapiens_hsa034502.52354355
15Proteasome_Homo sapiens_hsa030502.46332329
16Ribosome_Homo sapiens_hsa030102.41272547
17Basal transcription factors_Homo sapiens_hsa030222.33409968
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.14124673
19RNA degradation_Homo sapiens_hsa030182.13400338
20Propanoate metabolism_Homo sapiens_hsa006402.07269046
21mRNA surveillance pathway_Homo sapiens_hsa030151.93740468
22p53 signaling pathway_Homo sapiens_hsa041151.91029392
23Steroid biosynthesis_Homo sapiens_hsa001001.84435970
24Vitamin B6 metabolism_Homo sapiens_hsa007501.79622084
25Purine metabolism_Homo sapiens_hsa002301.64604573
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59269995
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.57007526
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56351219
29Systemic lupus erythematosus_Homo sapiens_hsa053221.48744576
30Pyruvate metabolism_Homo sapiens_hsa006201.47192880
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.41436977
32Fatty acid elongation_Homo sapiens_hsa000621.34530733
33Fatty acid metabolism_Homo sapiens_hsa012121.27543466
34Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.24037849
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.22564739
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.22306455
37Butanoate metabolism_Homo sapiens_hsa006501.14226622
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10774088
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09129997
40Oocyte meiosis_Homo sapiens_hsa041141.08419405
41Carbon metabolism_Homo sapiens_hsa012001.08016071
42Epstein-Barr virus infection_Homo sapiens_hsa051691.06640931
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.01113553
44Sulfur metabolism_Homo sapiens_hsa009200.97487173
45Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96782721
46Pentose and glucuronate interconversions_Homo sapiens_hsa000400.92368589
47Caffeine metabolism_Homo sapiens_hsa002320.88400723
48Fatty acid degradation_Homo sapiens_hsa000710.88355075
49Herpes simplex infection_Homo sapiens_hsa051680.86318933
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84859699
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84060097
52Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82835380
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82296515
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.76213581
55Primary bile acid biosynthesis_Homo sapiens_hsa001200.72343095
56Antigen processing and presentation_Homo sapiens_hsa046120.72071056
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.71281130
58Viral carcinogenesis_Homo sapiens_hsa052030.71005779
59Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71002974
60Fatty acid biosynthesis_Homo sapiens_hsa000610.70440987
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70178739
62Graft-versus-host disease_Homo sapiens_hsa053320.66733381
63Huntingtons disease_Homo sapiens_hsa050160.64476667
64MicroRNAs in cancer_Homo sapiens_hsa052060.63447165
65Arginine and proline metabolism_Homo sapiens_hsa003300.62393794
66Peroxisome_Homo sapiens_hsa041460.62121956
67Protein export_Homo sapiens_hsa030600.62030869
68HTLV-I infection_Homo sapiens_hsa051660.61254989
69Basal cell carcinoma_Homo sapiens_hsa052170.61160532
70Selenocompound metabolism_Homo sapiens_hsa004500.59766933
71Hippo signaling pathway_Homo sapiens_hsa043900.59557343
72Arginine biosynthesis_Homo sapiens_hsa002200.58606416
73Folate biosynthesis_Homo sapiens_hsa007900.56828368
74Thyroid cancer_Homo sapiens_hsa052160.56292745
75Alcoholism_Homo sapiens_hsa050340.55936185
76beta-Alanine metabolism_Homo sapiens_hsa004100.54421681
77Phenylalanine metabolism_Homo sapiens_hsa003600.51137784
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51010081
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49818480
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49157330
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48326388
82Small cell lung cancer_Homo sapiens_hsa052220.48099876
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46185911
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45094254
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.44749540
86Primary immunodeficiency_Homo sapiens_hsa053400.43818969
87Autoimmune thyroid disease_Homo sapiens_hsa053200.43583365
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42206575
89Arachidonic acid metabolism_Homo sapiens_hsa005900.41127687
90TGF-beta signaling pathway_Homo sapiens_hsa043500.40775705
91Maturity onset diabetes of the young_Homo sapiens_hsa049500.40658204
92Tryptophan metabolism_Homo sapiens_hsa003800.39656767
93Pentose phosphate pathway_Homo sapiens_hsa000300.39327702
94Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38992519
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38929737
96Chemical carcinogenesis_Homo sapiens_hsa052040.38738894
97Retinol metabolism_Homo sapiens_hsa008300.38212345
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.33566163
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33514349
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.33194658
101Starch and sucrose metabolism_Homo sapiens_hsa005000.33078168
102Tyrosine metabolism_Homo sapiens_hsa003500.33030295
103Glutathione metabolism_Homo sapiens_hsa004800.31736720
104Biosynthesis of amino acids_Homo sapiens_hsa012300.31270327
105Measles_Homo sapiens_hsa051620.31142537
106Metabolic pathways_Homo sapiens_hsa011000.30427964
107Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29257421
108Sphingolipid metabolism_Homo sapiens_hsa006000.28099636
109Intestinal immune network for IgA production_Homo sapiens_hsa046720.27627676
110Hepatitis B_Homo sapiens_hsa051610.26143106
111Lysine degradation_Homo sapiens_hsa003100.25089195
112Wnt signaling pathway_Homo sapiens_hsa043100.24738744
113Nitrogen metabolism_Homo sapiens_hsa009100.23793188
114Cyanoamino acid metabolism_Homo sapiens_hsa004600.23512962
115Hedgehog signaling pathway_Homo sapiens_hsa043400.22986326
116Linoleic acid metabolism_Homo sapiens_hsa005910.21597015
117Vitamin digestion and absorption_Homo sapiens_hsa049770.20886425
118Adherens junction_Homo sapiens_hsa045200.20781355
119Hematopoietic cell lineage_Homo sapiens_hsa046400.20082218
120Prostate cancer_Homo sapiens_hsa052150.20043520
121Other glycan degradation_Homo sapiens_hsa005110.19634981
122Central carbon metabolism in cancer_Homo sapiens_hsa052300.19390068
123Colorectal cancer_Homo sapiens_hsa052100.19362036
124Fat digestion and absorption_Homo sapiens_hsa049750.19293472
125Pathways in cancer_Homo sapiens_hsa052000.18731822
126N-Glycan biosynthesis_Homo sapiens_hsa005100.17557305
127FoxO signaling pathway_Homo sapiens_hsa040680.17475223
128Sulfur relay system_Homo sapiens_hsa041220.16862628
129Ovarian steroidogenesis_Homo sapiens_hsa049130.16710625
130Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.16584628
131Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.13557187
132Influenza A_Homo sapiens_hsa051640.13440062
133Allograft rejection_Homo sapiens_hsa053300.11808515
134Apoptosis_Homo sapiens_hsa042100.10778249
135Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.10095616
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.10044173
137Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.09806697
138Notch signaling pathway_Homo sapiens_hsa043300.08346748
139Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.07031039
140Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.06915812
141Renin-angiotensin system_Homo sapiens_hsa046140.05528400
142Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.04905849
143Parkinsons disease_Homo sapiens_hsa050120.04833418
144Legionellosis_Homo sapiens_hsa051340.04651312
145Melanoma_Homo sapiens_hsa052180.04418520

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