ERICH6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.91935357
2acrosome reaction (GO:0007340)9.64220979
3sperm-egg recognition (GO:0035036)9.60660956
4plasma membrane fusion (GO:0045026)9.06267398
5cell-cell recognition (GO:0009988)8.55843445
6reproduction (GO:0000003)8.43918043
7axonemal dynein complex assembly (GO:0070286)8.29917814
8epithelial cilium movement (GO:0003351)8.19096538
9binding of sperm to zona pellucida (GO:0007339)8.15398417
10spermatid development (GO:0007286)7.56993561
11regulation of cilium movement (GO:0003352)7.48431091
12motile cilium assembly (GO:0044458)7.27002200
13cilium movement (GO:0003341)7.22751671
14rRNA methylation (GO:0031167)7.13626659
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.71379061
16sperm capacitation (GO:0048240)6.68331915
17single fertilization (GO:0007338)6.61054721
18male meiosis (GO:0007140)6.48579716
19rRNA modification (GO:0000154)6.31674111
20negative regulation of inclusion body assembly (GO:0090084)5.97031879
21piRNA metabolic process (GO:0034587)5.94889570
22calcium ion-dependent exocytosis (GO:0017156)5.76305410
23fertilization (GO:0009566)5.41954184
24synaptonemal complex organization (GO:0070193)5.29726482
25protein polyglutamylation (GO:0018095)5.19479747
26phosphatidylethanolamine biosynthetic process (GO:0006646)5.13578735
27synaptonemal complex assembly (GO:0007130)5.06820050
28ventricular system development (GO:0021591)4.92469068
29regulation of phosphoprotein phosphatase activity (GO:0043666)4.89700278
30spermatogenesis (GO:0007283)4.86400517
31male gamete generation (GO:0048232)4.84005054
32regulation of microtubule-based movement (GO:0060632)4.75079604
33phosphatidylethanolamine metabolic process (GO:0046337)4.66043056
34cell recognition (GO:0008037)4.64337072
35microtubule severing (GO:0051013)4.60063575
36organic cation transport (GO:0015695)4.46719995
37regulation of inclusion body assembly (GO:0090083)4.46222279
38gamete generation (GO:0007276)4.44889503
39protein localization to cilium (GO:0061512)4.43060208
40RNA destabilization (GO:0050779)4.40390270
41cytidine metabolic process (GO:0046087)4.36646565
42cytidine catabolic process (GO:0006216)4.36646565
43cytidine deamination (GO:0009972)4.36646565
44cellular process involved in reproduction in multicellular organism (GO:0022412)4.24866546
45germ cell development (GO:0007281)4.08313573
46spermatid nucleus differentiation (GO:0007289)4.00062032
47microtubule depolymerization (GO:0007019)3.96124633
48centriole replication (GO:0007099)3.93629587
49DNA methylation involved in gamete generation (GO:0043046)3.91368802
50centriole assembly (GO:0098534)3.90365630
51DNA packaging (GO:0006323)3.86604206
52male meiosis I (GO:0007141)3.85299571
53intraciliary transport (GO:0042073)3.80089428
54response to pheromone (GO:0019236)3.79196340
55chromosome condensation (GO:0030261)3.75257957
56left/right pattern formation (GO:0060972)3.72527698
57lactate metabolic process (GO:0006089)3.71951659
58positive regulation of catecholamine secretion (GO:0033605)3.64489758
59calcium ion import (GO:0070509)3.60259418
60DNA deamination (GO:0045006)3.52817389
61pyrimidine ribonucleoside catabolic process (GO:0046133)3.48567554
62multicellular organismal reproductive process (GO:0048609)3.46771905
63chromosome organization involved in meiosis (GO:0070192)3.37992691
64axoneme assembly (GO:0035082)3.32808124
65histone exchange (GO:0043486)3.32593056
66detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.28504991
67cilium morphogenesis (GO:0060271)3.27604087
68protein K11-linked deubiquitination (GO:0035871)3.26747737
69cellular ketone body metabolic process (GO:0046950)3.25048446
70glycerol ether metabolic process (GO:0006662)3.20782591
71meiotic nuclear division (GO:0007126)3.19321423
72cilium organization (GO:0044782)3.17828088
73regulation of centriole replication (GO:0046599)3.17726903
74cilium assembly (GO:0042384)3.14426816
75intestinal epithelial cell development (GO:0060576)3.13773154
76locomotory exploration behavior (GO:0035641)3.13527508
77coenzyme catabolic process (GO:0009109)3.12511677
78peptidyl-glutamic acid modification (GO:0018200)3.12359470
79positive regulation of interleukin-8 secretion (GO:2000484)3.07791374
80kidney mesenchyme development (GO:0072074)3.07488211
81cellular component assembly involved in morphogenesis (GO:0010927)3.06862974
82membrane depolarization during action potential (GO:0086010)3.03908844
83oogenesis (GO:0048477)2.99799697
84microtubule-based movement (GO:0007018)2.97537872
85ether metabolic process (GO:0018904)2.96837944
86polyamine biosynthetic process (GO:0006596)2.93260872
87monoubiquitinated protein deubiquitination (GO:0035520)2.93184889
88single strand break repair (GO:0000012)2.92164705
89tryptophan catabolic process (GO:0006569)2.88590092
90indole-containing compound catabolic process (GO:0042436)2.88590092
91indolalkylamine catabolic process (GO:0046218)2.88590092
92positive regulation of glycolytic process (GO:0045821)2.88253446
93cellular response to pH (GO:0071467)2.87970777
94metanephric mesenchyme development (GO:0072075)2.87928756
95detection of calcium ion (GO:0005513)2.87419957
96meiosis I (GO:0007127)2.83314131
97ketone body metabolic process (GO:1902224)2.82067815
98regulation of transcription involved in cell fate commitment (GO:0060850)2.81014671
99relaxation of smooth muscle (GO:0044557)2.78419517
100positive regulation of glomerulus development (GO:0090193)2.77523531
101multicellular organismal development (GO:0007275)2.76940602
102amine biosynthetic process (GO:0009309)2.76446679
103gamma-aminobutyric acid transport (GO:0015812)2.75238769
104peptidyl-threonine dephosphorylation (GO:0035970)2.74023431
105negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.72217249
106seminiferous tubule development (GO:0072520)2.71839042
107protein targeting to Golgi (GO:0000042)2.71714172
108cellular biogenic amine biosynthetic process (GO:0042401)2.69524851
109sequestering of actin monomers (GO:0042989)2.66908057
110genitalia morphogenesis (GO:0035112)2.60559607
111protein localization to Golgi apparatus (GO:0034067)2.57018038
112smoothened signaling pathway (GO:0007224)2.56448239
113establishment of protein localization to Golgi (GO:0072600)2.53747529
114protein refolding (GO:0042026)2.53329611
115eye photoreceptor cell differentiation (GO:0001754)2.52521973
116photoreceptor cell differentiation (GO:0046530)2.52521973
117negative regulation of organelle assembly (GO:1902116)2.51459595
118positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.49077296
119polyol catabolic process (GO:0046174)2.48928681
120GTP biosynthetic process (GO:0006183)2.48092939
121ATP hydrolysis coupled proton transport (GO:0015991)2.46482208
122energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.46482208
123neuron cell-cell adhesion (GO:0007158)2.40015365
124nucleoside diphosphate phosphorylation (GO:0006165)2.36413944
125sexual reproduction (GO:0019953)2.33841868
126microtubule polymerization or depolymerization (GO:0031109)2.33787567
127retrograde transport, vesicle recycling within Golgi (GO:0000301)2.27761339
128detection of light stimulus involved in visual perception (GO:0050908)2.27170158
129detection of light stimulus involved in sensory perception (GO:0050962)2.27170158
130regulation of cilium assembly (GO:1902017)2.24863568
131cell redox homeostasis (GO:0045454)2.21858899
132synapsis (GO:0007129)2.17923572
133sensory perception of taste (GO:0050909)2.17596015
134response to acidic pH (GO:0010447)2.15976910
135urinary tract smooth muscle contraction (GO:0014848)2.15387143
136positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.14661825
137glycerol metabolic process (GO:0006071)2.14340889
138cell wall macromolecule metabolic process (GO:0044036)11.8050948
139cell wall macromolecule catabolic process (GO:0016998)11.8050948
140fusion of sperm to egg plasma membrane (GO:0007342)11.7650952
141sperm motility (GO:0030317)10.8235306
142acrosome assembly (GO:0001675)10.6560322
143multicellular organism reproduction (GO:0032504)10.1822552

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.69440081
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.29439974
3EZH2_22144423_ChIP-Seq_EOC_Human5.17100062
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.17464602
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.34338641
6FUS_26573619_Chip-Seq_HEK293_Human2.93093188
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.66218616
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66022622
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.51720445
10VDR_22108803_ChIP-Seq_LS180_Human2.45843107
11IGF1R_20145208_ChIP-Seq_DFB_Human2.35145125
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.31680683
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.29713403
14VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.17363785
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.13125000
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.10025084
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.08691402
18REST_21632747_ChIP-Seq_MESCs_Mouse2.04743774
19CBX2_27304074_Chip-Seq_ESCs_Mouse2.01925969
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.00269028
21MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.93982802
22GBX2_23144817_ChIP-Seq_PC3_Human1.89865956
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87669694
24TAF15_26573619_Chip-Seq_HEK293_Human1.87358050
25NANOG_20526341_ChIP-Seq_ESCs_Human1.83965515
26UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.75930940
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.71301607
28EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.71066338
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70500254
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.69555620
31KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.69539213
32ZNF274_21170338_ChIP-Seq_K562_Hela1.66627927
33NANOG_18555785_Chip-Seq_ESCs_Mouse1.65048045
34TOP2B_26459242_ChIP-Seq_MCF-7_Human1.62323950
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.60812110
36DROSHA_22980978_ChIP-Seq_HELA_Human1.59538418
37SMAD4_21741376_ChIP-Seq_EPCs_Human1.59110503
38SOX2_19829295_ChIP-Seq_ESCs_Human1.56810329
39NANOG_19829295_ChIP-Seq_ESCs_Human1.56810329
40ERG_20517297_ChIP-Seq_VCAP_Human1.56605793
41AR_25329375_ChIP-Seq_VCAP_Human1.56011768
42PCGF2_27294783_Chip-Seq_NPCs_Mouse1.54421391
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.53457063
44RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.52595751
45SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52489462
46KDM2B_26808549_Chip-Seq_REH_Human1.52133606
47EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.51659086
48OCT4_20526341_ChIP-Seq_ESCs_Human1.50585166
49NFE2_27457419_Chip-Seq_LIVER_Mouse1.47975842
50P53_22387025_ChIP-Seq_ESCs_Mouse1.46532875
51MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.46225877
52ELK4_26923725_Chip-Seq_MESODERM_Mouse1.45871007
53MYC_19829295_ChIP-Seq_ESCs_Human1.44340260
54RNF2_27304074_Chip-Seq_NSC_Mouse1.44050709
55CMYC_18555785_Chip-Seq_ESCs_Mouse1.43287916
56ERA_21632823_ChIP-Seq_H3396_Human1.42498968
57TAL1_26923725_Chip-Seq_HPCs_Mouse1.40321656
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.38713897
59FLI1_21867929_ChIP-Seq_TH2_Mouse1.38654029
60RAC3_21632823_ChIP-Seq_H3396_Human1.38508610
61P300_18555785_Chip-Seq_ESCs_Mouse1.37965451
62IRF8_22096565_ChIP-ChIP_GC-B_Human1.36706492
63SUZ12_18555785_Chip-Seq_ESCs_Mouse1.36686219
64TBL1_22424771_ChIP-Seq_293T_Human1.36371910
65EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.36035798
66EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.33077420
67SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.32627624
68OCT4_18555785_Chip-Seq_ESCs_Mouse1.32567870
69SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.32448872
70CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.32410722
71NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.32405752
72RUNX2_22187159_ChIP-Seq_PCA_Human1.32163190
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31696839
74KLF4_18555785_Chip-Seq_ESCs_Mouse1.31557078
75STAT3_18555785_Chip-Seq_ESCs_Mouse1.30733913
76GATA3_21878914_ChIP-Seq_MCF-7_Human1.30649250
77ETV1_20927104_ChIP-Seq_GIST48_Human1.30528219
78CBX2_22325352_ChIP-Seq_293T-Rex_Human1.30362649
79EZH2_27294783_Chip-Seq_ESCs_Mouse1.29927727
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.29799497
81SUZ12_27294783_Chip-Seq_ESCs_Mouse1.29737079
82REST_18959480_ChIP-ChIP_MESCs_Mouse1.28892538
83RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.27992042
84E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27535474
85RBPJ_21746931_ChIP-Seq_IB4_Human1.27326881
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26740307
87CBP_20019798_ChIP-Seq_JUKART_Human1.26740307
88TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26703598
89HNFA_21074721_ChIP-Seq_CACO-2_Human1.26285277
90ESRRB_18555785_Chip-Seq_ESCs_Mouse1.25861191
91SOX2_18555785_Chip-Seq_ESCs_Mouse1.25404270
92SMAD4_21799915_ChIP-Seq_A2780_Human1.25389107
93PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.24545753
94EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.24068710
95KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23621368
96E2F1_18555785_Chip-Seq_ESCs_Mouse1.23305995
97GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.22642423
98EZH2_27294783_Chip-Seq_NPCs_Mouse1.22515654
99CRX_20693478_ChIP-Seq_RETINA_Mouse1.22503612
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21420095
101AUTS2_25519132_ChIP-Seq_293T-REX_Human1.21367723
102NFYB_21822215_ChIP-Seq_K562_Human1.20985110
103POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20678843
104CTCF_18555785_Chip-Seq_ESCs_Mouse1.20410288
105RUNX1_27457419_Chip-Seq_LIVER_Mouse1.20047959
106NMYC_18555785_Chip-Seq_ESCs_Mouse1.18994593
107FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18956148
108PRDM14_20953172_ChIP-Seq_ESCs_Human1.18941739
109CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18908512
110PHF8_20622853_ChIP-Seq_HELA_Human1.18156793
111GATA1_26923725_Chip-Seq_HPCs_Mouse1.17980531
112BCAT_22108803_ChIP-Seq_LS180_Human1.17549381
113P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16958229
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15486032
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15486032
116ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14771368
117FOXA1_27270436_Chip-Seq_PROSTATE_Human1.14112283
118FOXA1_25329375_ChIP-Seq_VCAP_Human1.14112283
119WDR5_24793694_ChIP-Seq_LNCAP_Human1.13679205
120SMAD1_18555785_Chip-Seq_ESCs_Mouse1.12342726
121ZFX_18555785_Chip-Seq_ESCs_Mouse1.12154139
122STAT1_17558387_ChIP-Seq_HELA_Human1.12104583
123PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.11823053
124PU1_27457419_Chip-Seq_LIVER_Mouse1.11597977
125AR_21572438_ChIP-Seq_LNCaP_Human1.11308449
126NFYA_21822215_ChIP-Seq_K562_Human1.10959364
127CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10894054
128CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10809462
129FOXH1_21741376_ChIP-Seq_EPCs_Human1.10408988
130CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.10214419
131GATA6_21074721_ChIP-Seq_CACO-2_Human1.09963769
132STAT6_21828071_ChIP-Seq_BEAS2B_Human1.09795306
133GATA1_22025678_ChIP-Seq_K562_Human1.09149696
134P300_19829295_ChIP-Seq_ESCs_Human1.08705538
135SMAD3_21741376_ChIP-Seq_EPCs_Human1.08671132
136SMAD3_21741376_ChIP-Seq_ESCs_Human1.08319596
137SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08147140
138BMI1_23680149_ChIP-Seq_NPCS_Mouse1.07692067
139GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.07342794
140TDRD3_21172665_ChIP-Seq_MCF-7_Human1.07319529
141RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07249482
142GF1_26923725_Chip-Seq_HPCs_Mouse1.06570213
143ER_23166858_ChIP-Seq_MCF-7_Human1.05945265
144OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05920392
145TCF4_23295773_ChIP-Seq_U87_Human1.05537570
146GATA3_26560356_Chip-Seq_TH1_Human1.05424307
147RXR_22108803_ChIP-Seq_LS180_Human1.04910111
148TAF2_19829295_ChIP-Seq_ESCs_Human1.04747433
149FOXH1_21741376_ChIP-Seq_ESCs_Human1.04547412
150PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03911954
151NCOR_22424771_ChIP-Seq_293T_Human1.03755312
152CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03745682
153CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.03357387
154EED_16625203_ChIP-ChIP_MESCs_Mouse1.03225554
155RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03216880
156SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.03114635
157SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.02868113
158PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.01662103
159STAT3_23295773_ChIP-Seq_U87_Human1.01398692
160SOX9_26525672_Chip-Seq_HEART_Mouse1.00084262
161CDX2_22108803_ChIP-Seq_LS180_Human0.99660780
162OCT1_27270436_Chip-Seq_PROSTATE_Human0.98441696
163RNF2_27304074_Chip-Seq_ESCs_Mouse0.97879956
164SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.97077978
165AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.96096656
166DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96059336
167KAP1_22055183_ChIP-Seq_ESCs_Mouse0.95967667
168EZH2_27304074_Chip-Seq_ESCs_Mouse0.95762344
169TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95504439
170MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93958407

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive4.33327973
2MP0001929_abnormal_gametogenesis3.64724244
3MP0002653_abnormal_ependyma_morphology2.97347980
4MP0005423_abnormal_somatic_nervous2.77223350
5MP0003718_maternal_effect2.71506029
6MP0003878_abnormal_ear_physiology2.66181765
7MP0005377_hearing/vestibular/ear_phenot2.66181765
8MP0009046_muscle_twitch2.64606777
9MP0009780_abnormal_chondrocyte_physiolo2.53001914
10MP0004270_analgesia2.37989259
11MP0005389_reproductive_system_phenotype2.34290982
12MP0008877_abnormal_DNA_methylation2.34254335
13MP0001984_abnormal_olfaction2.31676849
14MP0002161_abnormal_fertility/fecundity2.26060742
15MP0002210_abnormal_sex_determination2.20083444
16MP0003315_abnormal_perineum_morphology2.17456169
17MP0003880_abnormal_central_pattern2.15328187
18MP0001485_abnormal_pinna_reflex2.13136988
19MP0010386_abnormal_urinary_bladder2.07679853
20MP0005410_abnormal_fertilization11.2257472
21MP0008789_abnormal_olfactory_epithelium1.97566744
22MP0002837_dystrophic_cardiac_calcinosis1.96362414
23MP0005394_taste/olfaction_phenotype1.95976557
24MP0005499_abnormal_olfactory_system1.95976557
25MP0001145_abnormal_male_reproductive1.87950101
26MP0005379_endocrine/exocrine_gland_phen1.77707975
27MP0001919_abnormal_reproductive_system1.70021133
28MP0003635_abnormal_synaptic_transmissio1.68663721
29MP0005551_abnormal_eye_electrophysiolog1.68101049
30MP0002272_abnormal_nervous_system1.68099393
31MP0000653_abnormal_sex_gland1.64736345
32MP0005623_abnormal_meninges_morphology1.62955830
33MP0006072_abnormal_retinal_apoptosis1.61190861
34MP0002734_abnormal_mechanical_nocicepti1.59850055
35MP0002909_abnormal_adrenal_gland1.59646356
36MP0001986_abnormal_taste_sensitivity1.54246898
37MP0001905_abnormal_dopamine_level1.53835757
38MP0002132_abnormal_respiratory_system1.50988905
39MP0004043_abnormal_pH_regulation1.48432764
40MP0002064_seizures1.46782040
41MP0004859_abnormal_synaptic_plasticity1.41700038
42MP0003724_increased_susceptibility_to1.39145821
43MP0002282_abnormal_trachea_morphology1.36796388
44MP0001486_abnormal_startle_reflex1.35647343
45MP0009745_abnormal_behavioral_response1.34833007
46MP0001765_abnormal_ion_homeostasis1.34599712
47MP0003183_abnormal_peptide_metabolism1.31018697
48MP0008004_abnormal_stomach_pH1.30136131
49MP0001968_abnormal_touch/_nociception1.28918707
50MP0003283_abnormal_digestive_organ1.26026630
51MP0002693_abnormal_pancreas_physiology1.25186719
52MP0002063_abnormal_learning/memory/cond1.23399519
53MP0005395_other_phenotype1.23391934
54MP0002102_abnormal_ear_morphology1.21161151
55MP0003879_abnormal_hair_cell1.19069426
56MP0002572_abnormal_emotion/affect_behav1.18949819
57MP0005646_abnormal_pituitary_gland1.18206333
58MP0008995_early_reproductive_senescence1.17870072
59MP0001501_abnormal_sleep_pattern1.15983100
60MP0008872_abnormal_physiological_respon1.15864051
61MP0005253_abnormal_eye_physiology1.13699493
62MP0003045_fibrosis1.13460514
63MP0006276_abnormal_autonomic_nervous1.08269217
64MP0000013_abnormal_adipose_tissue1.07635705
65MP0002163_abnormal_gland_morphology1.07401896
66MP0002736_abnormal_nociception_after1.05958216
67MP0002928_abnormal_bile_duct1.05709157
68MP0000230_abnormal_systemic_arterial1.04695802
69MP0002067_abnormal_sensory_capabilities1.03415707
70MP0003011_delayed_dark_adaptation1.02285144
71MP0002234_abnormal_pharynx_morphology1.01686092
72MP0001502_abnormal_circadian_rhythm1.01145905
73MP0001944_abnormal_pancreas_morphology0.99975394
74MP0002229_neurodegeneration0.99636571
75MP0003136_yellow_coat_color0.98439572
76MP0003195_calcinosis0.98138815
77MP0002254_reproductive_system_inflammat0.97141600
78MP0005595_abnormal_vascular_smooth0.97100030
79MP0004233_abnormal_muscle_weight0.97053668
80MP0002557_abnormal_social/conspecific_i0.96856293
81MP0000631_abnormal_neuroendocrine_gland0.95766984
82MP0005645_abnormal_hypothalamus_physiol0.95713754
83MP0003646_muscle_fatigue0.95332526
84MP0004742_abnormal_vestibular_system0.92821910
85MP0009278_abnormal_bone_marrow0.90668054
86MP0008569_lethality_at_weaning0.89153738
87MP0000026_abnormal_inner_ear0.89096102
88MP0000920_abnormal_myelination0.87931264
89MP0000955_abnormal_spinal_cord0.87497258
90MP0005310_abnormal_salivary_gland0.87328559
91MP0002160_abnormal_reproductive_system0.86363877
92MP0002882_abnormal_neuron_morphology0.86292079
93MP0000778_abnormal_nervous_system0.85657559
94MP0002233_abnormal_nose_morphology0.85212751
95MP0005670_abnormal_white_adipose0.85059422
96MP0002184_abnormal_innervation0.84744531
97MP0003137_abnormal_impulse_conducting0.83536137
98MP0000462_abnormal_digestive_system0.83289668
99MP0000538_abnormal_urinary_bladder0.82453036
100MP0005535_abnormal_body_temperature0.82040698
101MP0009697_abnormal_copulation0.80981187
102MP0002735_abnormal_chemical_nociception0.80717993
103MP0003936_abnormal_reproductive_system0.80520843
104MP0004811_abnormal_neuron_physiology0.79871866
105MP0000534_abnormal_ureter_morphology0.79668915
106MP0001545_abnormal_hematopoietic_system0.79376668
107MP0005397_hematopoietic_system_phenotyp0.79376668
108MP0000678_abnormal_parathyroid_gland0.79091061
109MP0002127_abnormal_cardiovascular_syste0.78587751
110MP0002066_abnormal_motor_capabilities/c0.77992355
111MP0001324_abnormal_eye_pigmentation0.77933834
112MP0003119_abnormal_digestive_system0.77027850
113MP0004134_abnormal_chest_morphology0.76991631
114MP0004885_abnormal_endolymph0.76294582
115MP0001970_abnormal_pain_threshold0.76093284
116MP0003634_abnormal_glial_cell0.75690772
117MP0000470_abnormal_stomach_morphology0.75541444
118MP0004085_abnormal_heartbeat0.73897552
119MP0001529_abnormal_vocalization0.73526195
120MP0004484_altered_response_of0.72991313
121MP0006036_abnormal_mitochondrial_physio0.72536212
122MP0003633_abnormal_nervous_system0.71699780
123MP0001299_abnormal_eye_distance/0.70680227
124MP0001119_abnormal_female_reproductive0.69175117
125MP0003329_amyloid_beta_deposits0.68286623
126MP0002752_abnormal_somatic_nervous0.67692581
127MP0002876_abnormal_thyroid_physiology0.67569494
128MP0000049_abnormal_middle_ear0.67152783
129MP0005636_abnormal_mineral_homeostasis0.66293938
130MP0002733_abnormal_thermal_nociception0.65952119
131MP0000569_abnormal_digit_pigmentation0.65575946
132MP0004142_abnormal_muscle_tone0.65333783
133MP0001664_abnormal_digestion0.65329883
134MP0001963_abnormal_hearing_physiology0.65282102
135MP0002078_abnormal_glucose_homeostasis0.64127241
136MP0001440_abnormal_grooming_behavior0.63427097
137MP0001879_abnormal_lymphatic_vessel0.63280442
138MP0002249_abnormal_larynx_morphology0.62960719
139MP0005174_abnormal_tail_pigmentation0.62654472
140MP0002277_abnormal_respiratory_mucosa0.62617845
141MP0001542_abnormal_bone_strength0.61662657
142MP0000613_abnormal_salivary_gland0.61365441
143MP0003631_nervous_system_phenotype0.60885784
144MP0005195_abnormal_posterior_eye0.59994234
145MP0004924_abnormal_behavior0.59912876
146MP0005386_behavior/neurological_phenoty0.59912876
147MP0000537_abnormal_urethra_morphology0.59275467
148MP0002152_abnormal_brain_morphology0.58813840
149MP0005647_abnormal_sex_gland0.57596176
150MP0004036_abnormal_muscle_relaxation0.57137358
151MP0001348_abnormal_lacrimal_gland0.57024060

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.35369640
2Abnormal respiratory motile cilium morphology (HP:0005938)7.85014582
3Abnormal respiratory epithelium morphology (HP:0012253)7.85014582
4Abnormal ciliary motility (HP:0012262)7.20908393
5Rhinitis (HP:0012384)6.86392432
6Chronic bronchitis (HP:0004469)6.71125487
7Severe visual impairment (HP:0001141)5.17269040
8Infertility (HP:0000789)4.88989992
9Nasal polyposis (HP:0100582)4.36879674
10Attenuation of retinal blood vessels (HP:0007843)4.34613397
11Chronic hepatic failure (HP:0100626)4.29497048
12Bronchiectasis (HP:0002110)3.96239503
13Abnormal rod and cone electroretinograms (HP:0008323)3.82380472
14Nephronophthisis (HP:0000090)3.82183520
15Medial flaring of the eyebrow (HP:0010747)3.82016398
16Bronchitis (HP:0012387)3.78806752
17Abnormality of the nasal mucosa (HP:0000433)3.39956865
18Hypoplasia of the uterus (HP:0000013)3.28582861
19Abnormal sex determination (HP:0012244)2.99993279
20Sex reversal (HP:0012245)2.99993279
21Male infertility (HP:0003251)2.97470367
22Gonadal dysgenesis (HP:0000133)2.95224178
23Recurrent sinusitis (HP:0011108)2.93563525
24Resting tremor (HP:0002322)2.91874393
25Absent rod-and cone-mediated responses on ERG (HP:0007688)2.87540173
26Gait imbalance (HP:0002141)2.84617056
27Abnormality of the renal medulla (HP:0100957)2.83495889
28Cone-rod dystrophy (HP:0000548)2.80758144
29Menstrual irregularities (HP:0000858)2.79673570
30Occipital encephalocele (HP:0002085)2.77370054
31Congenital primary aphakia (HP:0007707)2.76720438
32Molar tooth sign on MRI (HP:0002419)2.71859187
33Abnormality of midbrain morphology (HP:0002418)2.71859187
34Male pseudohermaphroditism (HP:0000037)2.71603682
35Congenital stationary night blindness (HP:0007642)2.68248856
36Progressive cerebellar ataxia (HP:0002073)2.65914579
37Abnormality of male internal genitalia (HP:0000022)2.61096599
38Hypoplastic ischia (HP:0003175)2.56538207
39Recurrent otitis media (HP:0000403)2.55848706
40Hyperinsulinemic hypoglycemia (HP:0000825)2.47690313
41Aplasia/hypoplasia of the uterus (HP:0008684)2.46351786
42Type II lissencephaly (HP:0007260)2.43496390
43Nephrogenic diabetes insipidus (HP:0009806)2.41452594
44Abnormality of macular pigmentation (HP:0008002)2.40197076
45Decreased central vision (HP:0007663)2.40033468
46Anencephaly (HP:0002323)2.38736053
47Pancreatic fibrosis (HP:0100732)2.37465892
48Genital tract atresia (HP:0001827)2.36696914
49Cerebellar dysplasia (HP:0007033)2.35931403
50Congenital sensorineural hearing impairment (HP:0008527)2.35423003
51Abnormality of the prostate (HP:0008775)2.35410266
52Vaginal atresia (HP:0000148)2.30319822
53Hypoalphalipoproteinemia (HP:0003233)2.30050999
54Abnormality of the ischium (HP:0003174)2.29139676
55Tubulointerstitial nephritis (HP:0001970)2.27253697
56Dyschromatopsia (HP:0007641)2.22048133
57Central scotoma (HP:0000603)2.20039313
58Asymmetric septal hypertrophy (HP:0001670)2.16306406
59Abnormal spermatogenesis (HP:0008669)2.15714589
60Hypoalbuminemia (HP:0003073)2.14621429
61Abnormal albumin level (HP:0012116)2.14621429
62Aplasia/Hypoplasia of the lens (HP:0008063)2.14236667
63Potter facies (HP:0002009)2.13432752
64Facial shape deformation (HP:0011334)2.13432752
65Genetic anticipation (HP:0003743)2.11129409
66Abnormality of the costochondral junction (HP:0000919)2.11087374
67Poor coordination (HP:0002370)2.06358099
68Sclerocornea (HP:0000647)2.05033053
69Reduced antithrombin III activity (HP:0001976)2.03064362
70Gastrointestinal infarctions (HP:0005244)2.01554884
71Postural instability (HP:0002172)2.00977128
72Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.5428933
73Absent/shortened dynein arms (HP:0200106)10.9100075
74Dynein arm defect of respiratory motile cilia (HP:0012255)10.9100075
75Tubulointerstitial abnormality (HP:0001969)1.99355288
76Neurofibrillary tangles (HP:0002185)1.99089849
77Symptomatic seizures (HP:0011145)1.96729559
78Abnormality of dental color (HP:0011073)1.94848032
79Hepatocellular necrosis (HP:0001404)1.94086376
80Abnormal drinking behavior (HP:0030082)1.93251514
81Polydipsia (HP:0001959)1.93251514
82Abnormality of the columella (HP:0009929)1.91580079
83Hypoplasia of the thymus (HP:0000778)1.91024232
84Amelogenesis imperfecta (HP:0000705)1.89853562
85Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.89436067
86Postaxial foot polydactyly (HP:0001830)1.89016067
87Aplasia/Hypoplasia of the tongue (HP:0010295)1.88748830
88Osteomalacia (HP:0002749)1.87516858
89Tubular atrophy (HP:0000092)1.87191518
90Abnormal urine output (HP:0012590)1.87065853
91True hermaphroditism (HP:0010459)1.86131194
92Congenital hepatic fibrosis (HP:0002612)1.86031135
93Increased corneal curvature (HP:0100692)1.85604086
94Keratoconus (HP:0000563)1.85604086
95Oral leukoplakia (HP:0002745)1.85045870
96Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84155215
97Recurrent bronchitis (HP:0002837)1.83927596
98Pulmonary fibrosis (HP:0002206)1.83468507
99Photophobia (HP:0000613)1.83003776
100Postaxial hand polydactyly (HP:0001162)1.81605598
101Inability to walk (HP:0002540)1.80845055
102Abnormality of the renal cortex (HP:0011035)1.80546943
103Myokymia (HP:0002411)1.80518906
104Portal hypertension (HP:0001409)1.80456738
105Cystic liver disease (HP:0006706)1.79415750
106Polyuria (HP:0000103)1.79213552
107Stage 5 chronic kidney disease (HP:0003774)1.75816497
108Anterior segment dysgenesis (HP:0007700)1.75311217
109Generalized aminoaciduria (HP:0002909)1.75082874
110Atonic seizures (HP:0010819)1.75030610
111Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74813427
112Hyperkalemia (HP:0002153)1.73825188
113Epileptic encephalopathy (HP:0200134)1.73576299
114Subcapsular cataract (HP:0000523)1.72849344
115Absent epiphyses (HP:0010577)1.72616912
116Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.72616912
117Renal Fanconi syndrome (HP:0001994)1.72474078
118Hemiparesis (HP:0001269)1.71860866
119Abnormality of the fovea (HP:0000493)1.69734106
120Optic nerve hypoplasia (HP:0000609)1.66851053
121Gaze-evoked nystagmus (HP:0000640)1.66219111
122Decreased circulating renin level (HP:0003351)1.63917363
123Delayed epiphyseal ossification (HP:0002663)1.63092958
124Hypoglycemic seizures (HP:0002173)1.61605390
125Tubulointerstitial fibrosis (HP:0005576)1.60357172
126Insulin-resistant diabetes mellitus (HP:0000831)1.58288828
127Median cleft lip (HP:0000161)1.57425007
128Abnormality of saccadic eye movements (HP:0000570)1.55120366
129Cerebral inclusion bodies (HP:0100314)1.54221787
130J-shaped sella turcica (HP:0002680)1.53971600
131Nephropathy (HP:0000112)1.53825322
132Retinal dysplasia (HP:0007973)1.53427681
133Chronic sinusitis (HP:0011109)1.52089828
134Choroideremia (HP:0001139)1.51635823
135Pancreatic cysts (HP:0001737)1.51218159
136Bony spicule pigmentary retinopathy (HP:0007737)1.50873596
137Microglossia (HP:0000171)1.50527717
138Abnormality of ocular smooth pursuit (HP:0000617)1.50293325
139Bell-shaped thorax (HP:0001591)1.49650308
140Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.48186954
141Retinitis pigmentosa (HP:0000510)1.47986560
142Constricted visual fields (HP:0001133)1.46400067
143Glucose intolerance (HP:0000833)1.45660784
144Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.44562014
145Degeneration of the lateral corticospinal tracts (HP:0002314)1.44562014
146Fibular hypoplasia (HP:0003038)1.44196280
147Abnormality of renal excretion (HP:0011036)1.42981541
148Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.42882121
149Type II diabetes mellitus (HP:0005978)1.42579681
150Limb ataxia (HP:0002070)1.42544812
151Oculomotor apraxia (HP:0000657)1.41701257
152Azoospermia (HP:0000027)1.41043284
153Short femoral neck (HP:0100864)1.40933959
154Cholecystitis (HP:0001082)1.39440737
155Abnormal gallbladder physiology (HP:0012438)1.39440737
156Short ribs (HP:0000773)1.39316897
157Abnormality of renal resorption (HP:0011038)1.38286910
158Scotoma (HP:0000575)1.38155056

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK36.54446102
2PDK46.54446102
3PLK44.78561615
4PRKD34.52193126
5PDK24.22128880
6TXK4.05162487
7TESK13.87604717
8ZAK3.29566995
9STK393.14997088
10TLK12.91506519
11MAP4K22.88968646
12WNK42.87004699
13TAF12.59378525
14VRK22.48218395
15ICK2.45480263
16PTK2B2.36622580
17NUAK12.34783040
18PNCK2.33634588
19INSRR2.14615267
20MARK32.13680599
21VRK12.04866028
22MAP3K41.87616091
23PASK1.81200554
24MST41.78228384
25PLK21.66076152
26BRSK21.57930548
27STK381.54672785
28BRD41.47948900
29MAP2K71.47565824
30STK38L1.45593483
31MAP2K21.44249120
32BMPR21.41062992
33PAK61.39867710
34TNIK1.39821363
35MAPK151.36170470
36MYLK1.29445970
37RPS6KA51.29145188
38MKNK11.26051256
39KIT1.26018282
40TIE11.20933860
41PIK3CG1.18905569
42GRK11.16425645
43WNK11.14463560
44PINK11.12837398
45PDK11.07436729
46MAPKAPK51.04994855
47DDR21.04392735
48RIPK41.03483383
49TNK21.03339504
50DYRK1B1.03186694
51CAMKK21.02481081
52MARK11.00565409
53TYRO30.99565853
54IRAK10.95224596
55OXSR10.94308941
56CASK0.93808944
57ADRBK20.93798617
58UHMK10.90700288
59IKBKB0.90501550
60NTRK10.89602890
61MAP3K60.89359895
62MAP2K40.87946911
63MAP2K60.86791481
64NTRK30.86420809
65MINK10.86311761
66MAP3K20.84066974
67OBSCN0.80020642
68PDPK10.79580919
69ACVR1B0.77269413
70FES0.76556193
71CDK30.75590191
72CSNK1G30.74640492
73EPHB10.74415415
74BMPR1B0.73666668
75CSNK1A1L0.73428357
76PRKCG0.73329398
77HIPK20.71452371
78FRK0.70017332
79EPHA40.68931381
80PBK0.68536009
81WNK30.65025026
82CAMK2D0.64997359
83DYRK20.64223594
84CAMK2A0.62801329
85IRAK20.61591310
86PAK30.61250946
87NEK20.61068861
88CDK50.60124837
89TEC0.58753755
90NTRK20.56724108
91IKBKE0.56103593
92CAMK1G0.55314215
93GRK70.53323273
94CSNK1G10.53240639
95SYK0.51305568
96CAMKK10.50960593
97NEK60.50919548
98MARK20.48407010
99PRKG20.48203519
100MAP3K90.45396401
101YES10.44895424
102SIK20.44888864
103ERBB30.44350517
104PKN10.44124326
105STK240.41905989
106TGFBR10.41551314
107BRAF0.41494567
108PRPF4B0.40809898
109ITK0.40055145
110MAPK130.39890203
111KDR0.39732268
112CCNB10.39713967
113GRK50.38324700
114CDC42BPA0.36301435
115BCR0.35980869
116PRKAA20.35901717
117PRKCE0.35738108
118CAMK10.35603789
119PRKCQ0.35487977
120CSNK1A10.34951544
121RPS6KA10.34199571
122ADRBK10.33536837
123CSNK1G20.33248075
124PRKCZ0.32722817
125EPHA30.32302737
126NLK0.31679979
127PRKACA0.30767700
128CAMK2B0.30471961
129BRSK10.30010088
130DYRK1A0.29925248
131DAPK20.29469703
132TAOK30.28197822
133CDK150.27839025
134PRKG10.27772913
135MAPK10.27712458
136RET0.27508129
137CAMK2G0.27453116
138EIF2AK20.27168160
139CDK180.26696929
140SGK4940.26662485
141SGK2230.26662485
142MAPK40.26371584
143MAP3K140.26268391
144MAP2K10.26231999
145CSNK1D0.25459428
146PRKCB0.25377056
147CDK140.24347649
148IGF1R0.24105654
149PRKD10.23730413
150ROCK10.23724353
151PRKCA0.23472807
152CHUK0.22802079
153CHEK20.21703477
154PRKCD0.21639236
155MAPK100.21386836
156PHKG20.21135359
157PHKG10.21135359
158PDGFRB0.20562290
159MUSK0.20530774
160CDK11A0.19840143
161PRKACG0.19757646
162MAP3K10.19271435
163PLK10.19202682
164PRKD20.19120215
165CDK70.18850066

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.72492832
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.48714074
3Butanoate metabolism_Homo sapiens_hsa006502.92622721
4Taste transduction_Homo sapiens_hsa047422.68418699
5Insulin secretion_Homo sapiens_hsa049112.54884888
6Synaptic vesicle cycle_Homo sapiens_hsa047212.34633932
7Nitrogen metabolism_Homo sapiens_hsa009102.34061879
8Sulfur metabolism_Homo sapiens_hsa009202.31592042
9Protein export_Homo sapiens_hsa030602.27874363
10Amphetamine addiction_Homo sapiens_hsa050312.15857300
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.13913103
12Collecting duct acid secretion_Homo sapiens_hsa049662.13362520
13Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.12738656
14Carbohydrate digestion and absorption_Homo sapiens_hsa049732.11762291
15Pyruvate metabolism_Homo sapiens_hsa006202.06077514
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.99835433
17Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.89690079
18Glucagon signaling pathway_Homo sapiens_hsa049221.86599340
19Linoleic acid metabolism_Homo sapiens_hsa005911.83786686
20Olfactory transduction_Homo sapiens_hsa047401.82304171
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.74138074
22Nicotine addiction_Homo sapiens_hsa050331.71085573
23Fatty acid biosynthesis_Homo sapiens_hsa000611.61774219
24Vitamin B6 metabolism_Homo sapiens_hsa007501.60957457
25Glutamatergic synapse_Homo sapiens_hsa047241.59665564
26Circadian entrainment_Homo sapiens_hsa047131.59388539
27Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.58162873
28Vibrio cholerae infection_Homo sapiens_hsa051101.57301672
29Fatty acid degradation_Homo sapiens_hsa000711.51193901
30Propanoate metabolism_Homo sapiens_hsa006401.49753381
31Cardiac muscle contraction_Homo sapiens_hsa042601.46462804
32Ether lipid metabolism_Homo sapiens_hsa005651.45034825
33Morphine addiction_Homo sapiens_hsa050321.43807601
34Phototransduction_Homo sapiens_hsa047441.43418716
35Huntingtons disease_Homo sapiens_hsa050161.42912404
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.42280724
37Renin secretion_Homo sapiens_hsa049241.41588847
38Dopaminergic synapse_Homo sapiens_hsa047281.40589104
39Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.40090325
40ABC transporters_Homo sapiens_hsa020101.39244855
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.39119394
42Long-term potentiation_Homo sapiens_hsa047201.38446629
43Cyanoamino acid metabolism_Homo sapiens_hsa004601.37780164
44Tryptophan metabolism_Homo sapiens_hsa003801.34370378
45Oxidative phosphorylation_Homo sapiens_hsa001901.34295588
46GABAergic synapse_Homo sapiens_hsa047271.31849951
47Fanconi anemia pathway_Homo sapiens_hsa034601.31811584
48Systemic lupus erythematosus_Homo sapiens_hsa053221.31210992
49Type II diabetes mellitus_Homo sapiens_hsa049301.28010662
50Gap junction_Homo sapiens_hsa045401.27115326
51Salivary secretion_Homo sapiens_hsa049701.25016769
52Cocaine addiction_Homo sapiens_hsa050301.24282676
53Vitamin digestion and absorption_Homo sapiens_hsa049771.21637701
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.21000396
55Glycosaminoglycan degradation_Homo sapiens_hsa005311.20673700
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.20105930
57Chemical carcinogenesis_Homo sapiens_hsa052041.12899409
58Graft-versus-host disease_Homo sapiens_hsa053321.09004548
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.06294528
60Glycerophospholipid metabolism_Homo sapiens_hsa005641.04487690
61Gastric acid secretion_Homo sapiens_hsa049711.04046679
62Primary immunodeficiency_Homo sapiens_hsa053401.03227596
63Proteasome_Homo sapiens_hsa030501.01772789
64Serotonergic synapse_Homo sapiens_hsa047261.01536661
65Cholinergic synapse_Homo sapiens_hsa047251.01522363
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.99437780
67Mineral absorption_Homo sapiens_hsa049780.97282302
68Glycerolipid metabolism_Homo sapiens_hsa005610.96299773
69Alzheimers disease_Homo sapiens_hsa050100.96287770
70cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95829753
71Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94214604
72Calcium signaling pathway_Homo sapiens_hsa040200.92861380
73Retinol metabolism_Homo sapiens_hsa008300.91970589
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.91797567
75Aldosterone synthesis and secretion_Homo sapiens_hsa049250.91330783
76Basal transcription factors_Homo sapiens_hsa030220.91307094
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91209908
78Sphingolipid metabolism_Homo sapiens_hsa006000.87838055
79Pancreatic secretion_Homo sapiens_hsa049720.87529455
80Dorso-ventral axis formation_Homo sapiens_hsa043200.86486625
81Selenocompound metabolism_Homo sapiens_hsa004500.86472029
82Phenylalanine metabolism_Homo sapiens_hsa003600.86143150
83RNA transport_Homo sapiens_hsa030130.85798804
84Oocyte meiosis_Homo sapiens_hsa041140.85788425
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.85320613
86Thyroid hormone synthesis_Homo sapiens_hsa049180.85151341
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85068984
88Antigen processing and presentation_Homo sapiens_hsa046120.84863176
89Peroxisome_Homo sapiens_hsa041460.84343884
90Purine metabolism_Homo sapiens_hsa002300.83601813
91Arachidonic acid metabolism_Homo sapiens_hsa005900.81821179
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81648133
93Pentose phosphate pathway_Homo sapiens_hsa000300.79683261
94Sulfur relay system_Homo sapiens_hsa041220.75427847
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75374352
96Steroid biosynthesis_Homo sapiens_hsa001000.75297090
97Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.74653915
98Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.73757266
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73568803
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72463631
101Estrogen signaling pathway_Homo sapiens_hsa049150.71462116
102Parkinsons disease_Homo sapiens_hsa050120.71051644
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70307957
104cAMP signaling pathway_Homo sapiens_hsa040240.67237530
105N-Glycan biosynthesis_Homo sapiens_hsa005100.65970711
106Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.64280582
107Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63749307
108Ovarian steroidogenesis_Homo sapiens_hsa049130.61057760
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60881961
110Arginine biosynthesis_Homo sapiens_hsa002200.57465401
111Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55142772
112Metabolic pathways_Homo sapiens_hsa011000.54891438
113Inositol phosphate metabolism_Homo sapiens_hsa005620.53132889
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52387795
115Glutathione metabolism_Homo sapiens_hsa004800.52045896
116Oxytocin signaling pathway_Homo sapiens_hsa049210.51277595
117Fatty acid elongation_Homo sapiens_hsa000620.51139862
118Allograft rejection_Homo sapiens_hsa053300.50946518
119Long-term depression_Homo sapiens_hsa047300.48920279
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46605458
121Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45414809
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45216981
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44734964
124Homologous recombination_Homo sapiens_hsa034400.44559669
125T cell receptor signaling pathway_Homo sapiens_hsa046600.44515259
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43901834
127Adipocytokine signaling pathway_Homo sapiens_hsa049200.42809991
128Caffeine metabolism_Homo sapiens_hsa002320.42334079
129PPAR signaling pathway_Homo sapiens_hsa033200.42084773
130Fructose and mannose metabolism_Homo sapiens_hsa000510.41151452
131Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41012133
132Protein digestion and absorption_Homo sapiens_hsa049740.40484254
133Alcoholism_Homo sapiens_hsa050340.40331719
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39316260
135Apoptosis_Homo sapiens_hsa042100.39314999
136Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.38717338
137Regulation of autophagy_Homo sapiens_hsa041400.38353672
138Tyrosine metabolism_Homo sapiens_hsa003500.37749331
139Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.36905303
140Renin-angiotensin system_Homo sapiens_hsa046140.36579772
141Hedgehog signaling pathway_Homo sapiens_hsa043400.35706516
142NOD-like receptor signaling pathway_Homo sapiens_hsa046210.35648935
143Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34435210
144Fat digestion and absorption_Homo sapiens_hsa049750.34154831
145Autoimmune thyroid disease_Homo sapiens_hsa053200.32839893
146Fatty acid metabolism_Homo sapiens_hsa012120.31496831
147Type I diabetes mellitus_Homo sapiens_hsa049400.31330266
148Circadian rhythm_Homo sapiens_hsa047100.29991172
149Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29286076
150Rheumatoid arthritis_Homo sapiens_hsa053230.28632530
151Endocytosis_Homo sapiens_hsa041440.27504908
152Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.26949579

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »