

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cellular extravasation (GO:0045123) | 7.23134125 |
| 2 | regulation of sister chromatid cohesion (GO:0007063) | 5.56673575 |
| 3 | opioid receptor signaling pathway (GO:0038003) | 5.55410110 |
| 4 | mesenchymal-epithelial cell signaling (GO:0060638) | 5.52736076 |
| 5 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 5.44463382 |
| 6 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 5.36429430 |
| 7 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 5.29667504 |
| 8 | GDP-mannose metabolic process (GO:0019673) | 5.25433604 |
| 9 | diterpenoid biosynthetic process (GO:0016102) | 5.22386743 |
| 10 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 5.20429607 |
| 11 | regulation of mitochondrial translation (GO:0070129) | 5.18773542 |
| 12 | regulation of MHC class II biosynthetic process (GO:0045346) | 5.13697909 |
| 13 | microglial cell activation (GO:0001774) | 5.13606572 |
| 14 | regulation of centriole replication (GO:0046599) | 4.95855965 |
| 15 | phosphatidylcholine biosynthetic process (GO:0006656) | 4.92237550 |
| 16 | arginine catabolic process (GO:0006527) | 4.91698859 |
| 17 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.83898802 |
| 18 | carnitine shuttle (GO:0006853) | 4.83019818 |
| 19 | phosphatidylethanolamine metabolic process (GO:0046337) | 4.82036747 |
| 20 | positive regulation of histone H3-K4 methylation (GO:0051571) | 4.80579842 |
| 21 | regulation of chemokine biosynthetic process (GO:0045073) | 4.78756508 |
| 22 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.69225685 |
| 23 | cell wall macromolecule catabolic process (GO:0016998) | 4.66273124 |
| 24 | dosage compensation (GO:0007549) | 4.62285072 |
| 25 | response to hepatocyte growth factor (GO:0035728) | 4.55612575 |
| 26 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 4.55612575 |
| 27 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 4.50979537 |
| 28 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 4.48713567 |
| 29 | protein K6-linked ubiquitination (GO:0085020) | 4.48657359 |
| 30 | induction of positive chemotaxis (GO:0050930) | 4.44813983 |
| 31 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.26106363 |
| 32 | mitotic sister chromatid cohesion (GO:0007064) | 4.21876593 |
| 33 | positive regulation of extracellular matrix organization (GO:1903055) | 4.05029113 |
| 34 | galactose catabolic process (GO:0019388) | 4.04472477 |
| 35 | negative regulation of histone acetylation (GO:0035067) | 4.01277880 |
| 36 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.99364456 |
| 37 | respiratory chain complex IV assembly (GO:0008535) | 3.98051821 |
| 38 | carnitine transmembrane transport (GO:1902603) | 3.84577910 |
| 39 | positive regulation of DNA biosynthetic process (GO:2000573) | 3.81793967 |
| 40 | fatty acid transmembrane transport (GO:1902001) | 3.80050179 |
| 41 | cell wall macromolecule metabolic process (GO:0044036) | 3.79018226 |
| 42 | negative regulation of peptidyl-lysine acetylation (GO:2000757) | 3.78518127 |
| 43 | terpenoid biosynthetic process (GO:0016114) | 3.78480651 |
| 44 | amino-acid betaine transport (GO:0015838) | 3.77148661 |
| 45 | carnitine transport (GO:0015879) | 3.77148661 |
| 46 | protein retention in ER lumen (GO:0006621) | 3.68671355 |
| 47 | negative regulation of protein acetylation (GO:1901984) | 3.60676227 |
| 48 | GMP metabolic process (GO:0046037) | 3.60551251 |
| 49 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.58704104 |
| 50 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.56182846 |
| 51 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.55245591 |
| 52 | kinetochore assembly (GO:0051382) | 3.50447565 |
| 53 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.42975431 |
| 54 | negative regulation of cell aging (GO:0090344) | 3.42203709 |
| 55 | cytochrome complex assembly (GO:0017004) | 3.38124674 |
| 56 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.38107801 |
| 57 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 3.37872169 |
| 58 | snRNA processing (GO:0016180) | 3.37313223 |
| 59 | snRNA metabolic process (GO:0016073) | 3.35652974 |
| 60 | female gonad development (GO:0008585) | 3.35571540 |
| 61 | platelet dense granule organization (GO:0060155) | 3.29851894 |
| 62 | peptidyl-lysine dimethylation (GO:0018027) | 3.28922214 |
| 63 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.26312441 |
| 64 | non-recombinational repair (GO:0000726) | 3.24192421 |
| 65 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.24192421 |
| 66 | muscle organ morphogenesis (GO:0048644) | 3.23855495 |
| 67 | regulation of histone H3-K9 methylation (GO:0051570) | 3.21915386 |
| 68 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902042) | 3.17512387 |
| 69 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.17146221 |
| 70 | negative regulation of growth of symbiont in host (GO:0044130) | 3.17091591 |
| 71 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.17091591 |
| 72 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.17091591 |
| 73 | regulation of growth of symbiont in host (GO:0044126) | 3.17091591 |
| 74 | regulation of gene expression by genetic imprinting (GO:0006349) | 3.15238020 |
| 75 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 3.13174923 |
| 76 | establishment of protein localization to peroxisome (GO:0072663) | 3.10641078 |
| 77 | protein localization to peroxisome (GO:0072662) | 3.10641078 |
| 78 | protein targeting to peroxisome (GO:0006625) | 3.10641078 |
| 79 | kinetochore organization (GO:0051383) | 3.09044754 |
| 80 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.08431649 |
| 81 | negative regulation of response to reactive oxygen species (GO:1901032) | 3.08245002 |
| 82 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.07639333 |
| 83 | meiotic chromosome segregation (GO:0045132) | 3.04043584 |
| 84 | hydrogen peroxide catabolic process (GO:0042744) | 3.00946955 |
| 85 | glial cell migration (GO:0008347) | 3.00084213 |
| 86 | neutrophil mediated immunity (GO:0002446) | 2.98416688 |
| 87 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.97972708 |
| 88 | phagocytosis, engulfment (GO:0006911) | 2.96340618 |
| 89 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.95393846 |
| 90 | L-phenylalanine metabolic process (GO:0006558) | 2.95393846 |
| 91 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.93928635 |
| 92 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.93928635 |
| 93 | macrophage chemotaxis (GO:0048246) | 2.89551754 |
| 94 | negative regulation of organelle assembly (GO:1902116) | 2.88695158 |
| 95 | positive regulation of interleukin-1 beta production (GO:0032731) | 2.88534717 |
| 96 | galactose metabolic process (GO:0006012) | 2.87868428 |
| 97 | viral entry into host cell (GO:0046718) | 2.83367596 |
| 98 | outer ear morphogenesis (GO:0042473) | 2.82040880 |
| 99 | secretory granule organization (GO:0033363) | 2.81995187 |
| 100 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 2.81147106 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 4.22224869 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.62918136 |
| 3 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.21140929 |
| 4 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.06372800 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.00011318 |
| 6 | KDM5A_27292631_Chip-Seq_BREAST_Human | 2.41112702 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.24076805 |
| 8 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.21395603 |
| 9 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.17151856 |
| 10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.15432334 |
| 11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.14877204 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12511522 |
| 13 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.10127797 |
| 14 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.07108861 |
| 15 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.06124502 |
| 16 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 2.03986790 |
| 17 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.03429991 |
| 18 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.6450085 |
| 19 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.99002182 |
| 20 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.97718544 |
| 21 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.90951666 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.85908456 |
| 23 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.78427618 |
| 24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.70343920 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.66942578 |
| 26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62999305 |
| 27 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.52232331 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.50803590 |
| 29 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.47923269 |
| 30 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.47151404 |
| 31 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.46888488 |
| 32 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.46355851 |
| 33 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.42729927 |
| 34 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.40976955 |
| 35 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.40071134 |
| 36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.33650797 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.32921273 |
| 38 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.32856722 |
| 39 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.30711433 |
| 40 | MYB_26560356_Chip-Seq_TH1_Human | 1.29381466 |
| 41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.28933833 |
| 42 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.27475416 |
| 43 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.24735935 |
| 44 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.23612782 |
| 45 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.21385214 |
| 46 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17145087 |
| 47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16132226 |
| 48 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15370205 |
| 49 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.12368870 |
| 50 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.11011326 |
| 51 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.10104243 |
| 52 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.09656877 |
| 53 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.08864055 |
| 54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.08646318 |
| 55 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.08526393 |
| 56 | CEBPB_22108803_ChIP-Seq_LS180_Human | 1.07311253 |
| 57 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06472306 |
| 58 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06472306 |
| 59 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.04846922 |
| 60 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.04754368 |
| 61 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04273445 |
| 62 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.03477380 |
| 63 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.03273870 |
| 64 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.02890837 |
| 65 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02592365 |
| 66 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.02102262 |
| 67 | MAF_26560356_Chip-Seq_TH2_Human | 1.01816899 |
| 68 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.01609640 |
| 69 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00284337 |
| 70 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.97839898 |
| 71 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96670467 |
| 72 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.96669569 |
| 73 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95632912 |
| 74 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95080500 |
| 75 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94484463 |
| 76 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.94463419 |
| 77 | UTX_26944678_Chip-Seq_JUKART_Human | 0.94292230 |
| 78 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.94009465 |
| 79 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.93544655 |
| 80 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.92641901 |
| 81 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92018603 |
| 82 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.90321602 |
| 83 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.87625926 |
| 84 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.86284482 |
| 85 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.85967305 |
| 86 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.85368924 |
| 87 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.85038657 |
| 88 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.84751210 |
| 89 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.82696164 |
| 90 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.82119612 |
| 91 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80462834 |
| 92 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.80157709 |
| 93 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.80100932 |
| 94 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.79827054 |
| 95 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.79044620 |
| 96 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.78053919 |
| 97 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.77456087 |
| 98 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.77358141 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.77133213 |
| 100 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.76005806 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 4.84600826 |
| 2 | MP0010094_abnormal_chromosome_stability | 4.09752190 |
| 3 | MP0000015_abnormal_ear_pigmentation | 3.80080372 |
| 4 | MP0003705_abnormal_hypodermis_morpholog | 3.56113041 |
| 5 | MP0005174_abnormal_tail_pigmentation | 3.19046016 |
| 6 | MP0003950_abnormal_plasma_membrane | 3.01753688 |
| 7 | MP0004381_abnormal_hair_follicle | 2.80601076 |
| 8 | MP0009278_abnormal_bone_marrow | 2.76517159 |
| 9 | MP0003786_premature_aging | 2.65116242 |
| 10 | MP0003111_abnormal_nucleus_morphology | 2.48460067 |
| 11 | MP0005058_abnormal_lysosome_morphology | 2.48094929 |
| 12 | MP0008057_abnormal_DNA_replication | 2.41266791 |
| 13 | MP0002139_abnormal_hepatobiliary_system | 2.31175093 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.23538244 |
| 15 | MP0005332_abnormal_amino_acid | 2.20325470 |
| 16 | MP0000427_abnormal_hair_cycle | 2.07118739 |
| 17 | MP0005075_abnormal_melanosome_morpholog | 2.06990582 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 2.01959637 |
| 19 | MP0003172_abnormal_lysosome_physiology | 1.97443020 |
| 20 | MP0008058_abnormal_DNA_repair | 1.95001061 |
| 21 | MP0003890_abnormal_embryonic-extraembry | 1.91775908 |
| 22 | MP0000371_diluted_coat_color | 1.86591684 |
| 23 | MP0001661_extended_life_span | 1.86001094 |
| 24 | MP0008438_abnormal_cutaneous_collagen | 1.85126128 |
| 25 | MP0008007_abnormal_cellular_replicative | 1.84447531 |
| 26 | MP0005360_urolithiasis | 1.78492250 |
| 27 | MP0002095_abnormal_skin_pigmentation | 1.74917854 |
| 28 | MP0002166_altered_tumor_susceptibility | 1.71847278 |
| 29 | MP0005397_hematopoietic_system_phenotyp | 1.64109949 |
| 30 | MP0001545_abnormal_hematopoietic_system | 1.64109949 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.59967391 |
| 32 | MP0002006_tumorigenesis | 1.55810776 |
| 33 | MP0001835_abnormal_antigen_presentation | 1.53918211 |
| 34 | MP0003656_abnormal_erythrocyte_physiolo | 1.49786448 |
| 35 | MP0008932_abnormal_embryonic_tissue | 1.47970455 |
| 36 | MP0010307_abnormal_tumor_latency | 1.46394471 |
| 37 | MP0003566_abnormal_cell_adhesion | 1.42821462 |
| 38 | MP0005084_abnormal_gallbladder_morpholo | 1.41435987 |
| 39 | MP0001243_abnormal_dermal_layer | 1.38310721 |
| 40 | MP0000470_abnormal_stomach_morphology | 1.37498102 |
| 41 | MP0000767_abnormal_smooth_muscle | 1.37167265 |
| 42 | MP0003077_abnormal_cell_cycle | 1.36743752 |
| 43 | MP0002269_muscular_atrophy | 1.36717603 |
| 44 | MP0004185_abnormal_adipocyte_glucose | 1.35875236 |
| 45 | MP0000749_muscle_degeneration | 1.30813311 |
| 46 | MP0002332_abnormal_exercise_endurance | 1.30648080 |
| 47 | MP0004134_abnormal_chest_morphology | 1.28882338 |
| 48 | MP0005023_abnormal_wound_healing | 1.27623994 |
| 49 | MP0001299_abnormal_eye_distance/ | 1.25550663 |
| 50 | MP0005408_hypopigmentation | 1.23470753 |
| 51 | MP0000003_abnormal_adipose_tissue | 1.21871788 |
| 52 | MP0002735_abnormal_chemical_nociception | 1.21742009 |
| 53 | MP0001905_abnormal_dopamine_level | 1.18476023 |
| 54 | MP0009780_abnormal_chondrocyte_physiolo | 1.17279262 |
| 55 | MP0002876_abnormal_thyroid_physiology | 1.16874714 |
| 56 | MP0000538_abnormal_urinary_bladder | 1.16101273 |
| 57 | MP0010386_abnormal_urinary_bladder | 1.13343247 |
| 58 | MP0002163_abnormal_gland_morphology | 1.11560040 |
| 59 | MP0008961_abnormal_basal_metabolism | 1.10465321 |
| 60 | MP0005266_abnormal_metabolism | 1.08609910 |
| 61 | MP0002971_abnormal_brown_adipose | 1.04506580 |
| 62 | MP0001756_abnormal_urination | 1.03096567 |
| 63 | MP0002396_abnormal_hematopoietic_system | 1.01039958 |
| 64 | MP0010368_abnormal_lymphatic_system | 1.01011743 |
| 65 | MP0005164_abnormal_response_to | 1.00319549 |
| 66 | MP0005253_abnormal_eye_physiology | 0.99006150 |
| 67 | MP0003943_abnormal_hepatobiliary_system | 0.98227818 |
| 68 | MP0005379_endocrine/exocrine_gland_phen | 0.92451989 |
| 69 | MP0009697_abnormal_copulation | 0.92089615 |
| 70 | MP0001958_emphysema | 0.91384958 |
| 71 | MP0003632_abnormal_nervous_system | 0.89562524 |
| 72 | MP0000358_abnormal_cell_content/ | 0.88278100 |
| 73 | MP0002111_abnormal_tail_morphology | 0.87763845 |
| 74 | MP0004808_abnormal_hematopoietic_stem | 0.86342808 |
| 75 | MP0002177_abnormal_outer_ear | 0.85496427 |
| 76 | MP0002075_abnormal_coat/hair_pigmentati | 0.81261111 |
| 77 | MP0003279_aneurysm | 0.81248806 |
| 78 | MP0005376_homeostasis/metabolism_phenot | 0.80306913 |
| 79 | MP0008770_decreased_survivor_rate | 0.79767417 |
| 80 | MP0005330_cardiomyopathy | 0.79123348 |
| 81 | MP0005503_abnormal_tendon_morphology | 0.77674681 |
| 82 | MP0000350_abnormal_cell_proliferation | 0.77633655 |
| 83 | MP0002733_abnormal_thermal_nociception | 0.77414420 |
| 84 | MP0004957_abnormal_blastocyst_morpholog | 0.77402301 |
| 85 | MP0000639_abnormal_adrenal_gland | 0.77347700 |
| 86 | MP0006036_abnormal_mitochondrial_physio | 0.77143937 |
| 87 | MP0002160_abnormal_reproductive_system | 0.72082169 |
| 88 | MP0005623_abnormal_meninges_morphology | 0.70220440 |
| 89 | MP0008873_increased_physiological_sensi | 0.69395764 |
| 90 | MP0001186_pigmentation_phenotype | 0.68891598 |
| 91 | MP0002009_preneoplasia | 0.68470059 |
| 92 | MP0001986_abnormal_taste_sensitivity | 0.68422366 |
| 93 | MP0002060_abnormal_skin_morphology | 0.68218406 |
| 94 | MP0002970_abnormal_white_adipose | 0.66159218 |
| 95 | MP0002019_abnormal_tumor_incidence | 0.65349766 |
| 96 | MP0000467_abnormal_esophagus_morphology | 0.63955358 |
| 97 | MP0009672_abnormal_birth_weight | 0.61752387 |
| 98 | MP0005319_abnormal_enzyme/_coenzyme | 0.61582159 |
| 99 | MP0005083_abnormal_biliary_tract | 0.59288665 |
| 100 | MP0003937_abnormal_limbs/digits/tail_de | 0.58070900 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 6.62671880 |
| 2 | Chromsome breakage (HP:0040012) | 5.58746711 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 5.53915969 |
| 4 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.15173040 |
| 5 | Abnormality of pyrimidine metabolism (HP:0004353) | 4.91670595 |
| 6 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.75632015 |
| 7 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 4.46885429 |
| 8 | Dyschromatopsia (HP:0007641) | 4.42572917 |
| 9 | Duplicated collecting system (HP:0000081) | 4.09963798 |
| 10 | Ureteral duplication (HP:0000073) | 3.81259422 |
| 11 | Abnormality of the ileum (HP:0001549) | 3.52330132 |
| 12 | Severe visual impairment (HP:0001141) | 3.48650268 |
| 13 | Abnormality of the renal collecting system (HP:0004742) | 3.47848922 |
| 14 | Abnormality of DNA repair (HP:0003254) | 3.45937680 |
| 15 | Vitreoretinal degeneration (HP:0000655) | 3.41878504 |
| 16 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.40321013 |
| 17 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.40321013 |
| 18 | Abnormality of glycolipid metabolism (HP:0010969) | 3.40321013 |
| 19 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.39610716 |
| 20 | Cerebral hemorrhage (HP:0001342) | 3.25688674 |
| 21 | Volvulus (HP:0002580) | 3.20826265 |
| 22 | Mitochondrial inheritance (HP:0001427) | 3.14020575 |
| 23 | Enlarged penis (HP:0000040) | 3.05966196 |
| 24 | Rhabdomyolysis (HP:0003201) | 3.02112637 |
| 25 | Pigmentary retinal degeneration (HP:0001146) | 2.90418017 |
| 26 | Fatigue (HP:0012378) | 2.88981424 |
| 27 | Hyperlipoproteinemia (HP:0010980) | 2.88842452 |
| 28 | Facial hemangioma (HP:0000329) | 2.86681789 |
| 29 | Meckel diverticulum (HP:0002245) | 2.86039129 |
| 30 | Deep palmar crease (HP:0006191) | 2.82786306 |
| 31 | Thin bony cortex (HP:0002753) | 2.79442527 |
| 32 | Increased hepatocellular lipid droplets (HP:0006565) | 2.77206254 |
| 33 | Abnormality of the preputium (HP:0100587) | 2.76357336 |
| 34 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.74732934 |
| 35 | Overlapping toe (HP:0001845) | 2.69884550 |
| 36 | Renal Fanconi syndrome (HP:0001994) | 2.67682223 |
| 37 | Increased muscle lipid content (HP:0009058) | 2.66256285 |
| 38 | Large for gestational age (HP:0001520) | 2.64987578 |
| 39 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.60285623 |
| 40 | Enlarged kidneys (HP:0000105) | 2.58313769 |
| 41 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.58151331 |
| 42 | Fair hair (HP:0002286) | 2.57588634 |
| 43 | Broad alveolar ridges (HP:0000187) | 2.54017209 |
| 44 | Hypophosphatemic rickets (HP:0004912) | 2.48085296 |
| 45 | Intestinal atresia (HP:0011100) | 2.45717201 |
| 46 | Clubbing of toes (HP:0100760) | 2.45038944 |
| 47 | Exertional dyspnea (HP:0002875) | 2.43855694 |
| 48 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.40596109 |
| 49 | Abnormality of the labia minora (HP:0012880) | 2.35679790 |
| 50 | Poor speech (HP:0002465) | 2.32182225 |
| 51 | Thrombocytosis (HP:0001894) | 2.30633877 |
| 52 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.29898399 |
| 53 | Absent radius (HP:0003974) | 2.23945758 |
| 54 | Unilateral renal agenesis (HP:0000122) | 2.22232891 |
| 55 | Horseshoe kidney (HP:0000085) | 2.22201607 |
| 56 | Arteriovenous malformation (HP:0100026) | 2.21104730 |
| 57 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.16173623 |
| 58 | Myelodysplasia (HP:0002863) | 2.15954581 |
| 59 | Albinism (HP:0001022) | 2.14479237 |
| 60 | Orthostatic hypotension (HP:0001278) | 2.11796579 |
| 61 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.10985492 |
| 62 | Absent forearm bone (HP:0003953) | 2.09254711 |
| 63 | Aplasia involving forearm bones (HP:0009822) | 2.09254711 |
| 64 | Embryonal renal neoplasm (HP:0011794) | 2.08952748 |
| 65 | Hypoalphalipoproteinemia (HP:0003233) | 2.04937201 |
| 66 | Muscle stiffness (HP:0003552) | 2.03999778 |
| 67 | Prolonged partial thromboplastin time (HP:0003645) | 2.02943149 |
| 68 | Reticulocytopenia (HP:0001896) | 1.99942868 |
| 69 | Abnormality of chromosome stability (HP:0003220) | 1.97967701 |
| 70 | Knee flexion contracture (HP:0006380) | 1.97158486 |
| 71 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.96318877 |
| 72 | Genu recurvatum (HP:0002816) | 1.94313862 |
| 73 | Enlarged epiphyses (HP:0010580) | 1.93662315 |
| 74 | Abnormality of the intrinsic pathway (HP:0010989) | 1.93617240 |
| 75 | Absent speech (HP:0001344) | 1.92630251 |
| 76 | Narrow palate (HP:0000189) | 1.92070907 |
| 77 | Pendular nystagmus (HP:0012043) | 1.88191846 |
| 78 | Epidermoid cyst (HP:0200040) | 1.87811380 |
| 79 | Abnormality of the alveolar ridges (HP:0006477) | 1.83980502 |
| 80 | Wide intermamillary distance (HP:0006610) | 1.82119086 |
| 81 | Progressive microcephaly (HP:0000253) | 1.81365999 |
| 82 | Myoglobinuria (HP:0002913) | 1.81265207 |
| 83 | Ulnar deviation of the wrist (HP:0003049) | 1.80423529 |
| 84 | Hepatocellular necrosis (HP:0001404) | 1.79678883 |
| 85 | Gingival bleeding (HP:0000225) | 1.79345438 |
| 86 | Abnormality of the common coagulation pathway (HP:0010990) | 1.79121909 |
| 87 | Epiphyseal stippling (HP:0010655) | 1.79084514 |
| 88 | Ureteral stenosis (HP:0000071) | 1.78213909 |
| 89 | Bulbous nose (HP:0000414) | 1.76443954 |
| 90 | Hemoptysis (HP:0002105) | 1.73498235 |
| 91 | Hematuria (HP:0000790) | 1.73212113 |
| 92 | Amyloidosis (HP:0011034) | 1.72870827 |
| 93 | Sloping forehead (HP:0000340) | 1.69053095 |
| 94 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.68798252 |
| 95 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.68798252 |
| 96 | Type I transferrin isoform profile (HP:0003642) | 1.67142301 |
| 97 | Periodontitis (HP:0000704) | 1.65916254 |
| 98 | Duodenal stenosis (HP:0100867) | 1.63741179 |
| 99 | Small intestinal stenosis (HP:0012848) | 1.63741179 |
| 100 | Abnormal hair whorl (HP:0010721) | 1.63669179 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.31548978 |
| 2 | MST4 | 4.26734879 |
| 3 | CDK12 | 3.84210764 |
| 4 | PRKD3 | 3.30284216 |
| 5 | BRD4 | 2.87404486 |
| 6 | CHEK2 | 2.85800393 |
| 7 | VRK2 | 2.74564176 |
| 8 | PKN2 | 2.38000865 |
| 9 | CDK6 | 2.28316638 |
| 10 | CDK4 | 2.15279256 |
| 11 | GRK7 | 2.12216974 |
| 12 | TGFBR2 | 2.12189045 |
| 13 | MAP3K12 | 2.06323898 |
| 14 | TNK2 | 2.00514801 |
| 15 | TTK | 1.99836357 |
| 16 | DDR2 | 1.95209469 |
| 17 | BMPR1B | 1.90298953 |
| 18 | STK10 | 1.58553625 |
| 19 | EIF2AK2 | 1.55542098 |
| 20 | ATR | 1.54198530 |
| 21 | GRK5 | 1.50662297 |
| 22 | DAPK1 | 1.49650189 |
| 23 | PAK2 | 1.43227319 |
| 24 | ZAP70 | 1.42621629 |
| 25 | ERN1 | 1.42034936 |
| 26 | RIPK1 | 1.33707406 |
| 27 | MYLK | 1.30285048 |
| 28 | STK38 | 1.29476585 |
| 29 | TEC | 1.20477006 |
| 30 | DYRK3 | 1.15988206 |
| 31 | MOS | 1.14200450 |
| 32 | CLK1 | 1.07517360 |
| 33 | SCYL2 | 1.05738026 |
| 34 | MAP3K4 | 1.04466058 |
| 35 | CDK9 | 1.03038908 |
| 36 | AURKB | 1.00539945 |
| 37 | CDK8 | 0.98104524 |
| 38 | NEK2 | 0.95870385 |
| 39 | MAP2K6 | 0.95192601 |
| 40 | VRK1 | 0.93271314 |
| 41 | PAK1 | 0.91365528 |
| 42 | CHEK1 | 0.90278615 |
| 43 | ZAK | 0.85087947 |
| 44 | KDR | 0.82344298 |
| 45 | PAK4 | 0.79460923 |
| 46 | EIF2AK3 | 0.79379527 |
| 47 | TRIB3 | 0.79059684 |
| 48 | PAK3 | 0.78882754 |
| 49 | PRKCI | 0.76523033 |
| 50 | TYK2 | 0.75935660 |
| 51 | ADRBK1 | 0.75730875 |
| 52 | PLK3 | 0.75015786 |
| 53 | MAP3K6 | 0.72753026 |
| 54 | MST1R | 0.70537609 |
| 55 | ATM | 0.69506011 |
| 56 | TRPM7 | 0.69107382 |
| 57 | LATS1 | 0.67127510 |
| 58 | INSRR | 0.66711901 |
| 59 | NUAK1 | 0.64945259 |
| 60 | INSR | 0.64773689 |
| 61 | PLK1 | 0.64490536 |
| 62 | PNCK | 0.62992003 |
| 63 | PRKD1 | 0.62553084 |
| 64 | MTOR | 0.61949779 |
| 65 | FRK | 0.61894168 |
| 66 | PLK4 | 0.61219807 |
| 67 | HIPK2 | 0.60099326 |
| 68 | MAP3K5 | 0.59717393 |
| 69 | CSNK2A2 | 0.58921615 |
| 70 | PIM2 | 0.58788756 |
| 71 | SYK | 0.58184805 |
| 72 | STK4 | 0.58101025 |
| 73 | WEE1 | 0.53884340 |
| 74 | MAP4K1 | 0.52614134 |
| 75 | MINK1 | 0.52440953 |
| 76 | CDK1 | 0.51705412 |
| 77 | KIT | 0.48107413 |
| 78 | FLT3 | 0.47678801 |
| 79 | HCK | 0.44741723 |
| 80 | FGFR1 | 0.44687755 |
| 81 | MAP3K2 | 0.43165726 |
| 82 | PRKCQ | 0.42625863 |
| 83 | AKT1 | 0.41836143 |
| 84 | PTK2B | 0.40331053 |
| 85 | BRAF | 0.40015246 |
| 86 | PRKDC | 0.39903408 |
| 87 | PIK3CA | 0.39899317 |
| 88 | CAMK2D | 0.39760969 |
| 89 | RPS6KA4 | 0.39671476 |
| 90 | ABL1 | 0.39372795 |
| 91 | ADRBK2 | 0.39340627 |
| 92 | YES1 | 0.38103675 |
| 93 | AURKA | 0.37932766 |
| 94 | AKT3 | 0.37920660 |
| 95 | PRKACB | 0.35688874 |
| 96 | RPS6KB2 | 0.35357869 |
| 97 | PLK2 | 0.35260578 |
| 98 | RET | 0.33758287 |
| 99 | CSNK2A1 | 0.33626650 |
| 100 | CDK2 | 0.31166751 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 4.84308708 |
| 2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.70357559 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 4.08677350 |
| 4 | Base excision repair_Homo sapiens_hsa03410 | 3.25545439 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.89578116 |
| 6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.74576124 |
| 7 | Lysine degradation_Homo sapiens_hsa00310 | 2.45836863 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.28027960 |
| 9 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.18689756 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.03118256 |
| 11 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.99396801 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.99295065 |
| 13 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.91835939 |
| 14 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.67017182 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.65350293 |
| 16 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.63602463 |
| 17 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.62716367 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.60855988 |
| 19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.55763564 |
| 20 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.47854187 |
| 21 | Mismatch repair_Homo sapiens_hsa03430 | 1.45988371 |
| 22 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.43614606 |
| 23 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.36829590 |
| 24 | Galactose metabolism_Homo sapiens_hsa00052 | 1.36262836 |
| 25 | Peroxisome_Homo sapiens_hsa04146 | 1.33474085 |
| 26 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.31612107 |
| 27 | Shigellosis_Homo sapiens_hsa05131 | 1.29628601 |
| 28 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.28940300 |
| 29 | Other glycan degradation_Homo sapiens_hsa00511 | 1.27360664 |
| 30 | RNA transport_Homo sapiens_hsa03013 | 1.25047667 |
| 31 | Cell cycle_Homo sapiens_hsa04110 | 1.24140389 |
| 32 | Homologous recombination_Homo sapiens_hsa03440 | 1.23440749 |
| 33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.22818390 |
| 34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.22113964 |
| 35 | Proteasome_Homo sapiens_hsa03050 | 1.21472327 |
| 36 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.19028300 |
| 37 | Lysosome_Homo sapiens_hsa04142 | 1.18948505 |
| 38 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.15356182 |
| 39 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.15278225 |
| 40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.14400081 |
| 41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.06166429 |
| 42 | RNA polymerase_Homo sapiens_hsa03020 | 1.05629936 |
| 43 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.04706400 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03400224 |
| 45 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01740807 |
| 46 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.01285590 |
| 47 | Spliceosome_Homo sapiens_hsa03040 | 0.97885741 |
| 48 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.95284816 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90758987 |
| 50 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.88259501 |
| 51 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.85483494 |
| 52 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.84245462 |
| 53 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.83190210 |
| 54 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80066094 |
| 55 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.76527511 |
| 56 | RNA degradation_Homo sapiens_hsa03018 | 0.75705610 |
| 57 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.75496151 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.72241507 |
| 59 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.66118828 |
| 60 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.61993903 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61469276 |
| 62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.61269775 |
| 63 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.61243512 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55787711 |
| 65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53378156 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51404305 |
| 67 | Melanoma_Homo sapiens_hsa05218 | 0.51340593 |
| 68 | Ribosome_Homo sapiens_hsa03010 | 0.49401017 |
| 69 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.47708823 |
| 70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.45848495 |
| 71 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.44726156 |
| 72 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.44698995 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.42624463 |
| 74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.41348362 |
| 75 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.41312607 |
| 76 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.40538427 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40345435 |
| 78 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.40165485 |
| 79 | Protein export_Homo sapiens_hsa03060 | 0.39621286 |
| 80 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.39617044 |
| 81 | Phototransduction_Homo sapiens_hsa04744 | 0.38904018 |
| 82 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38465888 |
| 83 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.37107802 |
| 84 | Pertussis_Homo sapiens_hsa05133 | 0.36215679 |
| 85 | Parkinsons disease_Homo sapiens_hsa05012 | 0.34800287 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32380013 |
| 87 | Alzheimers disease_Homo sapiens_hsa05010 | 0.31764792 |
| 88 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.31391862 |
| 89 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.31279870 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.31101429 |
| 91 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.29538838 |
| 92 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.26483869 |
| 93 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26307040 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.25951374 |
| 95 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.23356817 |
| 96 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.23231608 |
| 97 | Focal adhesion_Homo sapiens_hsa04510 | 0.22617114 |
| 98 | Malaria_Homo sapiens_hsa05144 | 0.22146625 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.19412720 |
| 100 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.18075218 |

