

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.04209113 |
| 2 | DNA deamination (GO:0045006) | 4.58441586 |
| 3 | protein complex biogenesis (GO:0070271) | 4.56722595 |
| 4 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.40334907 |
| 5 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.37634164 |
| 6 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.37634164 |
| 7 | NADH dehydrogenase complex assembly (GO:0010257) | 4.37634164 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.32203541 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.32203541 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 4.28199198 |
| 11 | proteasome assembly (GO:0043248) | 4.08716513 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.06213545 |
| 13 | DNA double-strand break processing (GO:0000729) | 3.89561920 |
| 14 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.85678518 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.83351858 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.82458097 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.82094479 |
| 18 | respiratory chain complex IV assembly (GO:0008535) | 3.76410985 |
| 19 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.71934257 |
| 20 | termination of RNA polymerase III transcription (GO:0006386) | 3.71934257 |
| 21 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.68094268 |
| 22 | respiratory electron transport chain (GO:0022904) | 3.67210260 |
| 23 | rRNA modification (GO:0000154) | 3.64408649 |
| 24 | electron transport chain (GO:0022900) | 3.61128886 |
| 25 | peptidyl-histidine modification (GO:0018202) | 3.60824506 |
| 26 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.59355769 |
| 27 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.56077423 |
| 28 | cytochrome complex assembly (GO:0017004) | 3.50949570 |
| 29 | organelle disassembly (GO:1903008) | 3.50331377 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.48978714 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.48978714 |
| 32 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.47407524 |
| 33 | pseudouridine synthesis (GO:0001522) | 3.45887213 |
| 34 | ribonucleoprotein complex disassembly (GO:0032988) | 3.44916999 |
| 35 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.37212942 |
| 36 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.37212942 |
| 37 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.37212942 |
| 38 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.37115964 |
| 39 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.37115964 |
| 40 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.35384164 |
| 41 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.31657608 |
| 42 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.31573912 |
| 43 | protein targeting to mitochondrion (GO:0006626) | 3.31558837 |
| 44 | positive regulation of ligase activity (GO:0051351) | 3.23958207 |
| 45 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.23427670 |
| 46 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.23299754 |
| 47 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.21907353 |
| 48 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.21907353 |
| 49 | protein localization to mitochondrion (GO:0070585) | 3.15755041 |
| 50 | regulation of mitochondrial translation (GO:0070129) | 3.15220255 |
| 51 | spliceosomal snRNP assembly (GO:0000387) | 3.13759258 |
| 52 | protein neddylation (GO:0045116) | 3.12311256 |
| 53 | establishment of protein localization to mitochondrion (GO:0072655) | 3.08217068 |
| 54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.08004644 |
| 55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.08004644 |
| 56 | histone H2A acetylation (GO:0043968) | 3.07642385 |
| 57 | tRNA processing (GO:0008033) | 3.04546838 |
| 58 | ribosomal small subunit biogenesis (GO:0042274) | 3.02911677 |
| 59 | cullin deneddylation (GO:0010388) | 3.01305204 |
| 60 | protein deneddylation (GO:0000338) | 2.98617087 |
| 61 | iron-sulfur cluster assembly (GO:0016226) | 2.95879357 |
| 62 | metallo-sulfur cluster assembly (GO:0031163) | 2.95879357 |
| 63 | ribosomal large subunit biogenesis (GO:0042273) | 2.94237148 |
| 64 | protein-cofactor linkage (GO:0018065) | 2.93191532 |
| 65 | rRNA methylation (GO:0031167) | 2.92009812 |
| 66 | cellular component biogenesis (GO:0044085) | 2.91670271 |
| 67 | postreplication repair (GO:0006301) | 2.91376131 |
| 68 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.89804725 |
| 69 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.89679289 |
| 70 | translation (GO:0006412) | 2.88146973 |
| 71 | positive regulation of granulocyte differentiation (GO:0030854) | 2.86099525 |
| 72 | rRNA processing (GO:0006364) | 2.83413669 |
| 73 | regulation of ligase activity (GO:0051340) | 2.82097628 |
| 74 | positive regulation of protein homodimerization activity (GO:0090073) | 2.81941018 |
| 75 | ribosome assembly (GO:0042255) | 2.79498203 |
| 76 | rRNA metabolic process (GO:0016072) | 2.74966494 |
| 77 | mannosylation (GO:0097502) | 2.74101578 |
| 78 | ribosomal small subunit assembly (GO:0000028) | 2.73349809 |
| 79 | mitochondrial RNA metabolic process (GO:0000959) | 2.71942165 |
| 80 | histone mRNA metabolic process (GO:0008334) | 2.71825583 |
| 81 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.71660913 |
| 82 | amino acid salvage (GO:0043102) | 2.69906881 |
| 83 | L-methionine salvage (GO:0071267) | 2.69906881 |
| 84 | L-methionine biosynthetic process (GO:0071265) | 2.69906881 |
| 85 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.68129531 |
| 86 | tRNA metabolic process (GO:0006399) | 2.67084320 |
| 87 | negative regulation of protein ubiquitination (GO:0031397) | 2.63838634 |
| 88 | positive regulation of cell cycle arrest (GO:0071158) | 2.63138861 |
| 89 | ncRNA processing (GO:0034470) | 2.62693636 |
| 90 | kinetochore assembly (GO:0051382) | 2.62347947 |
| 91 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.61221838 |
| 92 | hydrogen ion transmembrane transport (GO:1902600) | 2.61037241 |
| 93 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.60770455 |
| 94 | DNA damage response, detection of DNA damage (GO:0042769) | 2.60769533 |
| 95 | regulation of cellular amine metabolic process (GO:0033238) | 2.60380564 |
| 96 | maturation of SSU-rRNA (GO:0030490) | 2.59847984 |
| 97 | translational termination (GO:0006415) | 2.59473370 |
| 98 | regulation of helicase activity (GO:0051095) | 2.59465279 |
| 99 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.57091386 |
| 100 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.56086916 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.04883129 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.97427316 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.43679551 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.27510181 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.07717979 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.86062869 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.65588988 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.35257995 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.31112137 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 3.22156422 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.94827996 |
| 12 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.74155953 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.72133833 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61772026 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.57079546 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.51874865 |
| 17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.47922646 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.43360029 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.35176099 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.33253739 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.31775261 |
| 22 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.27287181 |
| 23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.24040522 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.21973862 |
| 25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.21365560 |
| 26 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.17901689 |
| 27 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.15526028 |
| 28 | VDR_22108803_ChIP-Seq_LS180_Human | 2.08470139 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.07933025 |
| 30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.06123797 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.05802242 |
| 32 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.98956814 |
| 33 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.98313065 |
| 34 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.97797814 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.92640709 |
| 36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.87074597 |
| 37 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.85567939 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.83182177 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.79657674 |
| 40 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.72713224 |
| 41 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.72031774 |
| 42 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.71020923 |
| 43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.68988775 |
| 44 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.65260695 |
| 45 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.63474655 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.60859028 |
| 47 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.60082180 |
| 48 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.58039767 |
| 49 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.56833365 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.54007159 |
| 51 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.53600400 |
| 52 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49252434 |
| 53 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36941189 |
| 54 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.36817840 |
| 55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.35057757 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.34690706 |
| 57 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.33580618 |
| 58 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.33319329 |
| 59 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.30512704 |
| 60 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.30019729 |
| 61 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24396570 |
| 62 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.22878711 |
| 63 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.20731083 |
| 64 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17875643 |
| 65 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16842974 |
| 66 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.16332406 |
| 67 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.15654810 |
| 68 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.10873334 |
| 69 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.06620535 |
| 70 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.04502698 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98693270 |
| 72 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.98097511 |
| 73 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.97330173 |
| 74 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94023599 |
| 75 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.93169720 |
| 76 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.93130559 |
| 77 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.92632709 |
| 78 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90428031 |
| 79 | MYB_26560356_Chip-Seq_TH2_Human | 0.89611167 |
| 80 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89381710 |
| 81 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.87630302 |
| 82 | FUS_26573619_Chip-Seq_HEK293_Human | 0.87119315 |
| 83 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.86218946 |
| 84 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.84732785 |
| 85 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.82509066 |
| 86 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.78952386 |
| 87 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.76222999 |
| 88 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.75005341 |
| 89 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.74322801 |
| 90 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.72780777 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.72628483 |
| 92 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.71132805 |
| 93 | NCOR_22424771_ChIP-Seq_293T_Human | 0.67615330 |
| 94 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.67190640 |
| 95 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.66928411 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.66664015 |
| 97 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.65331770 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.65284725 |
| 99 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.64836021 |
| 100 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.64767556 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.34808450 |
| 2 | MP0010094_abnormal_chromosome_stability | 2.84288446 |
| 3 | MP0002102_abnormal_ear_morphology | 2.75883570 |
| 4 | MP0003786_premature_aging | 2.73065649 |
| 5 | MP0008057_abnormal_DNA_replication | 2.69284064 |
| 6 | MP0003693_abnormal_embryo_hatching | 2.57207266 |
| 7 | MP0008995_early_reproductive_senescence | 2.47268848 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.36171153 |
| 9 | MP0003763_abnormal_thymus_physiology | 2.27674373 |
| 10 | MP0006036_abnormal_mitochondrial_physio | 2.25711342 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.14933487 |
| 12 | MP0006035_abnormal_mitochondrial_morpho | 1.97969571 |
| 13 | MP0003077_abnormal_cell_cycle | 1.90028584 |
| 14 | MP0003186_abnormal_redox_activity | 1.88749102 |
| 15 | MP0000372_irregular_coat_pigmentation | 1.87339948 |
| 16 | MP0001873_stomach_inflammation | 1.87171392 |
| 17 | MP0003111_abnormal_nucleus_morphology | 1.86244828 |
| 18 | MP0001986_abnormal_taste_sensitivity | 1.80765706 |
| 19 | MP0005671_abnormal_response_to | 1.71148151 |
| 20 | MP0001529_abnormal_vocalization | 1.69674182 |
| 21 | MP0008789_abnormal_olfactory_epithelium | 1.68085590 |
| 22 | MP0008007_abnormal_cellular_replicative | 1.65812443 |
| 23 | MP0004957_abnormal_blastocyst_morpholog | 1.62524103 |
| 24 | MP0003950_abnormal_plasma_membrane | 1.60172326 |
| 25 | MP0002132_abnormal_respiratory_system | 1.55657760 |
| 26 | MP0005394_taste/olfaction_phenotype | 1.48405019 |
| 27 | MP0005499_abnormal_olfactory_system | 1.48405019 |
| 28 | MP0002277_abnormal_respiratory_mucosa | 1.47767740 |
| 29 | MP0006292_abnormal_olfactory_placode | 1.46680043 |
| 30 | MP0003718_maternal_effect | 1.43533511 |
| 31 | MP0001764_abnormal_homeostasis | 1.43231726 |
| 32 | MP0006072_abnormal_retinal_apoptosis | 1.43191222 |
| 33 | MP0002837_dystrophic_cardiac_calcinosis | 1.38979076 |
| 34 | MP0009333_abnormal_splenocyte_physiolog | 1.38814282 |
| 35 | MP0002736_abnormal_nociception_after | 1.35603296 |
| 36 | MP0001853_heart_inflammation | 1.34797771 |
| 37 | MP0008872_abnormal_physiological_respon | 1.34669188 |
| 38 | MP0005075_abnormal_melanosome_morpholog | 1.31965954 |
| 39 | MP0003787_abnormal_imprinting | 1.28718733 |
| 40 | MP0004142_abnormal_muscle_tone | 1.28160954 |
| 41 | MP0000703_abnormal_thymus_morphology | 1.27622580 |
| 42 | MP0001919_abnormal_reproductive_system | 1.27206113 |
| 43 | MP0001905_abnormal_dopamine_level | 1.24144031 |
| 44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.23839906 |
| 45 | MP0001800_abnormal_humoral_immune | 1.20364948 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.15595853 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.14294757 |
| 48 | MP0009785_altered_susceptibility_to | 1.14207099 |
| 49 | MP0005084_abnormal_gallbladder_morpholo | 1.10884838 |
| 50 | MP0008932_abnormal_embryonic_tissue | 1.09822535 |
| 51 | MP0001984_abnormal_olfaction | 1.09020619 |
| 52 | MP0000749_muscle_degeneration | 1.08816904 |
| 53 | MP0001929_abnormal_gametogenesis | 1.08361685 |
| 54 | MP0002210_abnormal_sex_determination | 1.05977182 |
| 55 | MP0002638_abnormal_pupillary_reflex | 1.05861509 |
| 56 | MP0002160_abnormal_reproductive_system | 1.04223648 |
| 57 | MP0002163_abnormal_gland_morphology | 1.04141658 |
| 58 | MP0005389_reproductive_system_phenotype | 1.03825804 |
| 59 | MP0001835_abnormal_antigen_presentation | 1.03627413 |
| 60 | MP0005253_abnormal_eye_physiology | 1.03624851 |
| 61 | MP0003880_abnormal_central_pattern | 0.98544935 |
| 62 | MP0006276_abnormal_autonomic_nervous | 0.97018785 |
| 63 | MP0002398_abnormal_bone_marrow | 0.95154795 |
| 64 | MP0002723_abnormal_immune_serum | 0.93095133 |
| 65 | MP0002722_abnormal_immune_system | 0.92473400 |
| 66 | MP0000358_abnormal_cell_content/ | 0.92381935 |
| 67 | MP0000313_abnormal_cell_death | 0.92129493 |
| 68 | MP0003121_genomic_imprinting | 0.91635119 |
| 69 | MP0008961_abnormal_basal_metabolism | 0.91613666 |
| 70 | MP0002420_abnormal_adaptive_immunity | 0.91508093 |
| 71 | MP0000015_abnormal_ear_pigmentation | 0.90357043 |
| 72 | MP0005266_abnormal_metabolism | 0.90163765 |
| 73 | MP0000689_abnormal_spleen_morphology | 0.90088835 |
| 74 | MP0005645_abnormal_hypothalamus_physiol | 0.88382091 |
| 75 | MP0001819_abnormal_immune_cell | 0.86693402 |
| 76 | MP0009046_muscle_twitch | 0.86215146 |
| 77 | MP0005646_abnormal_pituitary_gland | 0.85672322 |
| 78 | MP0003315_abnormal_perineum_morphology | 0.85447214 |
| 79 | MP0005310_abnormal_salivary_gland | 0.85174752 |
| 80 | MP0009697_abnormal_copulation | 0.84594646 |
| 81 | MP0000716_abnormal_immune_system | 0.83928552 |
| 82 | MP0005000_abnormal_immune_tolerance | 0.82858996 |
| 83 | MP0002019_abnormal_tumor_incidence | 0.82811371 |
| 84 | MP0005551_abnormal_eye_electrophysiolog | 0.80239330 |
| 85 | MP0002653_abnormal_ependyma_morphology | 0.79652477 |
| 86 | MP0001188_hyperpigmentation | 0.79473748 |
| 87 | MP0003698_abnormal_male_reproductive | 0.79181269 |
| 88 | MP0003221_abnormal_cardiomyocyte_apopto | 0.77533479 |
| 89 | MP0002693_abnormal_pancreas_physiology | 0.76785863 |
| 90 | MP0004742_abnormal_vestibular_system | 0.75574879 |
| 91 | MP0002452_abnormal_antigen_presenting | 0.75448576 |
| 92 | MP0001145_abnormal_male_reproductive | 0.75053607 |
| 93 | MP0004381_abnormal_hair_follicle | 0.74462355 |
| 94 | MP0000653_abnormal_sex_gland | 0.73823094 |
| 95 | MP0002822_catalepsy | 0.73446812 |
| 96 | MP0005410_abnormal_fertilization | 0.72855666 |
| 97 | MP0001790_abnormal_immune_system | 0.72853439 |
| 98 | MP0005387_immune_system_phenotype | 0.72853439 |
| 99 | MP0005174_abnormal_tail_pigmentation | 0.71559040 |
| 100 | MP0002429_abnormal_blood_cell | 0.71376965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.51729116 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.33441390 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.23991414 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.02635233 |
| 5 | Increased CSF lactate (HP:0002490) | 3.96949838 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.89613186 |
| 7 | Acute encephalopathy (HP:0006846) | 3.77531362 |
| 8 | Hepatic necrosis (HP:0002605) | 3.63454268 |
| 9 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.34900690 |
| 10 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.34900690 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.25718236 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 3.22213893 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.19232311 |
| 14 | Aplastic anemia (HP:0001915) | 3.10887852 |
| 15 | Increased serum lactate (HP:0002151) | 3.02448690 |
| 16 | Cerebral edema (HP:0002181) | 2.82711886 |
| 17 | Lactic acidosis (HP:0003128) | 2.74898432 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 2.71586780 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63739429 |
| 20 | Microvesicular hepatic steatosis (HP:0001414) | 2.61132987 |
| 21 | Increased intramyocellular lipid droplets (HP:0012240) | 2.60136137 |
| 22 | Methylmalonic acidemia (HP:0002912) | 2.59944458 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 2.57498442 |
| 24 | Methylmalonic aciduria (HP:0012120) | 2.50134771 |
| 25 | Pancreatic cysts (HP:0001737) | 2.47183825 |
| 26 | Hypoplasia of the thymus (HP:0000778) | 2.44872002 |
| 27 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.42279254 |
| 28 | Abnormal protein glycosylation (HP:0012346) | 2.42279254 |
| 29 | Abnormal glycosylation (HP:0012345) | 2.42279254 |
| 30 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.42279254 |
| 31 | Pancytopenia (HP:0001876) | 2.42056713 |
| 32 | Renal cortical cysts (HP:0000803) | 2.38934913 |
| 33 | Type I transferrin isoform profile (HP:0003642) | 2.37407544 |
| 34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.35958765 |
| 35 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.31499917 |
| 36 | Cerebral hypomyelination (HP:0006808) | 2.29071518 |
| 37 | Increased muscle lipid content (HP:0009058) | 2.28402673 |
| 38 | Medial flaring of the eyebrow (HP:0010747) | 2.25904559 |
| 39 | Exercise intolerance (HP:0003546) | 2.25718360 |
| 40 | Respiratory failure (HP:0002878) | 2.24703717 |
| 41 | Reduced antithrombin III activity (HP:0001976) | 2.19404333 |
| 42 | IgG deficiency (HP:0004315) | 2.17388191 |
| 43 | Lethargy (HP:0001254) | 2.17220312 |
| 44 | Optic disc pallor (HP:0000543) | 2.16844392 |
| 45 | Progressive microcephaly (HP:0000253) | 2.14218802 |
| 46 | Panhypogammaglobulinemia (HP:0003139) | 2.13789573 |
| 47 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.11770513 |
| 48 | Abnormality of alanine metabolism (HP:0010916) | 2.11770513 |
| 49 | Hyperalaninemia (HP:0003348) | 2.11770513 |
| 50 | Hypothermia (HP:0002045) | 2.11312900 |
| 51 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.10845725 |
| 52 | CNS demyelination (HP:0007305) | 2.09646974 |
| 53 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.09305144 |
| 54 | Severe combined immunodeficiency (HP:0004430) | 2.06851545 |
| 55 | Meckel diverticulum (HP:0002245) | 2.04718402 |
| 56 | Absent thumb (HP:0009777) | 2.03861507 |
| 57 | Molar tooth sign on MRI (HP:0002419) | 2.02000382 |
| 58 | Abnormality of midbrain morphology (HP:0002418) | 2.02000382 |
| 59 | Abnormality of the ileum (HP:0001549) | 2.01501716 |
| 60 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.00511940 |
| 61 | Leukodystrophy (HP:0002415) | 2.00498751 |
| 62 | Increased serum pyruvate (HP:0003542) | 1.96333078 |
| 63 | Respiratory difficulties (HP:0002880) | 1.96111749 |
| 64 | Abnormality of the pons (HP:0007361) | 1.95695994 |
| 65 | Exertional dyspnea (HP:0002875) | 1.93228084 |
| 66 | Pancreatic fibrosis (HP:0100732) | 1.92686973 |
| 67 | Emotional lability (HP:0000712) | 1.91984002 |
| 68 | Abnormality of the preputium (HP:0100587) | 1.91762781 |
| 69 | Abnormality of the labia minora (HP:0012880) | 1.90138604 |
| 70 | Hypoplasia of the pons (HP:0012110) | 1.88685420 |
| 71 | Colon cancer (HP:0003003) | 1.87525240 |
| 72 | Nephrogenic diabetes insipidus (HP:0009806) | 1.87426500 |
| 73 | Abnormality of chromosome stability (HP:0003220) | 1.86348026 |
| 74 | Carpal bone hypoplasia (HP:0001498) | 1.84720774 |
| 75 | Calf muscle hypertrophy (HP:0008981) | 1.84483485 |
| 76 | Congenital primary aphakia (HP:0007707) | 1.83761524 |
| 77 | Generalized aminoaciduria (HP:0002909) | 1.83757320 |
| 78 | Reticulocytopenia (HP:0001896) | 1.82632021 |
| 79 | Eosinophilia (HP:0001880) | 1.82558111 |
| 80 | Type 2 muscle fiber atrophy (HP:0003554) | 1.82033561 |
| 81 | True hermaphroditism (HP:0010459) | 1.81525348 |
| 82 | Macrocytic anemia (HP:0001972) | 1.81143607 |
| 83 | Gait imbalance (HP:0002141) | 1.79665046 |
| 84 | Poor suck (HP:0002033) | 1.76252891 |
| 85 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.75918549 |
| 86 | Abnormality of the anterior horn cell (HP:0006802) | 1.72230670 |
| 87 | Degeneration of anterior horn cells (HP:0002398) | 1.72230670 |
| 88 | Abnormality of renal resorption (HP:0011038) | 1.72151470 |
| 89 | Sensory axonal neuropathy (HP:0003390) | 1.68555116 |
| 90 | Myelodysplasia (HP:0002863) | 1.68077103 |
| 91 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.67477380 |
| 92 | CNS hypomyelination (HP:0003429) | 1.67007911 |
| 93 | Abnormality of eosinophils (HP:0001879) | 1.66121052 |
| 94 | Congenital stationary night blindness (HP:0007642) | 1.65889858 |
| 95 | Abnormality of the renal cortex (HP:0011035) | 1.65652240 |
| 96 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.65236846 |
| 97 | Dicarboxylic aciduria (HP:0003215) | 1.65236846 |
| 98 | Premature ovarian failure (HP:0008209) | 1.64840665 |
| 99 | Squamous cell carcinoma (HP:0002860) | 1.64382587 |
| 100 | Thyroiditis (HP:0100646) | 1.62488982 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 3.63554026 |
| 2 | VRK2 | 3.30203643 |
| 3 | SRPK1 | 3.10433450 |
| 4 | FRK | 2.70817761 |
| 5 | STK16 | 2.51306335 |
| 6 | TXK | 2.43596308 |
| 7 | CDC7 | 2.34455416 |
| 8 | TRIM28 | 2.30010866 |
| 9 | NME1 | 2.28045053 |
| 10 | EIF2AK3 | 2.26538513 |
| 11 | VRK1 | 2.25057404 |
| 12 | ZAK | 2.24457824 |
| 13 | MAP4K2 | 1.88547308 |
| 14 | TESK2 | 1.87865418 |
| 15 | NUAK1 | 1.80374568 |
| 16 | MARK3 | 1.79634595 |
| 17 | PDK2 | 1.78666938 |
| 18 | MAP2K7 | 1.75917026 |
| 19 | PINK1 | 1.71490540 |
| 20 | CCNB1 | 1.64960043 |
| 21 | CSNK1G3 | 1.55896070 |
| 22 | CSNK1A1L | 1.51654468 |
| 23 | BMPR1B | 1.49574245 |
| 24 | NME2 | 1.46360430 |
| 25 | MAPKAPK5 | 1.41475735 |
| 26 | CDK8 | 1.36924624 |
| 27 | TLK1 | 1.31220828 |
| 28 | WNK3 | 1.29922534 |
| 29 | STK38L | 1.29712706 |
| 30 | EIF2AK1 | 1.28944945 |
| 31 | CSNK1G1 | 1.26441863 |
| 32 | ADRBK2 | 1.26412830 |
| 33 | BCKDK | 1.25042234 |
| 34 | MAPK13 | 1.17218247 |
| 35 | BRSK2 | 1.17105524 |
| 36 | MAP4K1 | 1.14330982 |
| 37 | MAP3K4 | 1.13267657 |
| 38 | DYRK3 | 1.12643035 |
| 39 | CSNK1G2 | 1.11131683 |
| 40 | ATR | 1.09111341 |
| 41 | MUSK | 1.06175033 |
| 42 | RPS6KA4 | 1.05470485 |
| 43 | DYRK2 | 1.03112992 |
| 44 | PLK3 | 1.02569002 |
| 45 | PLK4 | 0.99222279 |
| 46 | NEK1 | 0.97964382 |
| 47 | MST4 | 0.96683026 |
| 48 | RPS6KA5 | 0.94787996 |
| 49 | TEC | 0.94509549 |
| 50 | GRK1 | 0.92760370 |
| 51 | IKBKB | 0.90867536 |
| 52 | MKNK2 | 0.89068010 |
| 53 | PLK1 | 0.86157236 |
| 54 | DAPK1 | 0.83742952 |
| 55 | TSSK6 | 0.83452519 |
| 56 | PBK | 0.78213545 |
| 57 | CAMKK2 | 0.76255394 |
| 58 | ITK | 0.75032844 |
| 59 | CDK3 | 0.74535087 |
| 60 | IKBKE | 0.71576756 |
| 61 | TAOK3 | 0.69344301 |
| 62 | TNK2 | 0.67825231 |
| 63 | SIK3 | 0.66842432 |
| 64 | NEK2 | 0.65796617 |
| 65 | CLK1 | 0.65273888 |
| 66 | AURKB | 0.65206036 |
| 67 | BCR | 0.64662346 |
| 68 | PIM2 | 0.63808991 |
| 69 | CSNK2A1 | 0.63411803 |
| 70 | ERBB3 | 0.61842608 |
| 71 | MAPKAPK3 | 0.59093424 |
| 72 | CSNK2A2 | 0.58684117 |
| 73 | ATM | 0.57299825 |
| 74 | BRSK1 | 0.56651722 |
| 75 | TAF1 | 0.56276198 |
| 76 | BTK | 0.55366772 |
| 77 | KDR | 0.54410085 |
| 78 | CHEK2 | 0.53793860 |
| 79 | AURKA | 0.50404494 |
| 80 | BLK | 0.50128923 |
| 81 | MAP3K12 | 0.50113923 |
| 82 | SYK | 0.48818028 |
| 83 | AKT3 | 0.48237191 |
| 84 | PASK | 0.47512804 |
| 85 | GRK6 | 0.47024838 |
| 86 | CDK4 | 0.46176225 |
| 87 | PIK3CG | 0.44396567 |
| 88 | BMPR2 | 0.44116147 |
| 89 | CSNK1A1 | 0.42690528 |
| 90 | CDK19 | 0.42636491 |
| 91 | PRKCQ | 0.42081370 |
| 92 | CHEK1 | 0.42075822 |
| 93 | MKNK1 | 0.40308913 |
| 94 | LYN | 0.40091128 |
| 95 | STK4 | 0.38322958 |
| 96 | LCK | 0.38090042 |
| 97 | BRD4 | 0.37563174 |
| 98 | WEE1 | 0.35785286 |
| 99 | INSRR | 0.34440853 |
| 100 | CSNK1D | 0.33770554 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.68282602 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.78067210 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.60671422 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.39267235 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.26968532 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.93243718 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.85810947 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.74736373 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.72615439 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.70814993 |
| 11 | Spliceosome_Homo sapiens_hsa03040 | 2.47041374 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.37737482 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.26500342 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.06450287 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 2.02483997 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.92645028 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.82957922 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.82634808 |
| 19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.80455893 |
| 20 | Base excision repair_Homo sapiens_hsa03410 | 1.78789988 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.73810859 |
| 22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.63774242 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.61374920 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.59534750 |
| 25 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.56465068 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.44427160 |
| 27 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.35379575 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.32071165 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30987050 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12679805 |
| 31 | Sulfur relay system_Homo sapiens_hsa04122 | 1.11710244 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.09000861 |
| 33 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06573532 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.05368280 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.04283418 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.02923042 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.97505811 |
| 38 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.92443484 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.92142712 |
| 40 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.92019077 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.90210320 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 0.86814385 |
| 43 | Phototransduction_Homo sapiens_hsa04744 | 0.84947011 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.84550209 |
| 45 | Cell cycle_Homo sapiens_hsa04110 | 0.82759695 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.80075808 |
| 47 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.79580005 |
| 48 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77709212 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.76788305 |
| 50 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.71453800 |
| 51 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.66321408 |
| 52 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65695995 |
| 53 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.63653975 |
| 54 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60509763 |
| 55 | Circadian rhythm_Homo sapiens_hsa04710 | 0.60390656 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56145853 |
| 57 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55812809 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.54634038 |
| 59 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.54619108 |
| 60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53269819 |
| 61 | Allograft rejection_Homo sapiens_hsa05330 | 0.52034888 |
| 62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.49737288 |
| 63 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.49487556 |
| 64 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.47927043 |
| 65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47369572 |
| 66 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.46556589 |
| 67 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.45986092 |
| 68 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.45769959 |
| 69 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.45757670 |
| 70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45426933 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.41331680 |
| 72 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41009786 |
| 73 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.40253750 |
| 74 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.39356176 |
| 75 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.38283645 |
| 76 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37912119 |
| 77 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.37907884 |
| 78 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37630876 |
| 79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.37611501 |
| 80 | Asthma_Homo sapiens_hsa05310 | 0.37229013 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.36404320 |
| 82 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.36146951 |
| 83 | Measles_Homo sapiens_hsa05162 | 0.33276176 |
| 84 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.32966359 |
| 85 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32442804 |
| 86 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.31837073 |
| 87 | Legionellosis_Homo sapiens_hsa05134 | 0.30070917 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29510037 |
| 89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.29306807 |
| 90 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.28625922 |
| 91 | Alcoholism_Homo sapiens_hsa05034 | 0.28210608 |
| 92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27243622 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.24790371 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.24113466 |
| 95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.23877765 |
| 96 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.23397533 |
| 97 | Nicotine addiction_Homo sapiens_hsa05033 | 0.22973421 |
| 98 | Apoptosis_Homo sapiens_hsa04210 | 0.22182777 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22062345 |
| 100 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.21713860 |

