

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | basic amino acid transport (GO:0015802) | 7.54344515 |
| 2 | sulfation (GO:0051923) | 7.05684845 |
| 3 | chemosensory behavior (GO:0007635) | 7.01533868 |
| 4 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 6.80988461 |
| 5 | inner cell mass cell proliferation (GO:0001833) | 6.62683710 |
| 6 | G-protein coupled receptor internalization (GO:0002031) | 6.46159663 |
| 7 | heart valve formation (GO:0003188) | 6.43491557 |
| 8 | mRNA polyadenylation (GO:0006378) | 6.24709407 |
| 9 | Notch signaling involved in heart development (GO:0061314) | 5.99506059 |
| 10 | cellular response to ATP (GO:0071318) | 5.89860515 |
| 11 | negative regulation of axon guidance (GO:1902668) | 5.74916527 |
| 12 | response to pheromone (GO:0019236) | 5.73732514 |
| 13 | RNA polyadenylation (GO:0043631) | 5.66466045 |
| 14 | negative regulation of platelet activation (GO:0010544) | 5.46294409 |
| 15 | post-anal tail morphogenesis (GO:0036342) | 5.41142918 |
| 16 | primitive streak formation (GO:0090009) | 5.23694793 |
| 17 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 5.20338598 |
| 18 | cardiac right ventricle morphogenesis (GO:0003215) | 5.06393443 |
| 19 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 5.04895752 |
| 20 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 4.98735573 |
| 21 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 4.98735573 |
| 22 | cardiac epithelial to mesenchymal transition (GO:0060317) | 4.93329279 |
| 23 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 4.78843859 |
| 24 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 4.77297403 |
| 25 | histone mRNA metabolic process (GO:0008334) | 4.77209714 |
| 26 | heart trabecula morphogenesis (GO:0061384) | 4.21286768 |
| 27 | coronary vasculature morphogenesis (GO:0060977) | 3.99070137 |
| 28 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.94283546 |
| 29 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 3.88028571 |
| 30 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.81850252 |
| 31 | negative regulation of digestive system process (GO:0060457) | 3.80816455 |
| 32 | dopamine transport (GO:0015872) | 3.78196542 |
| 33 | regulation of vasculogenesis (GO:2001212) | 3.72109678 |
| 34 | retinal cone cell development (GO:0046549) | 3.67183287 |
| 35 | forebrain neuron development (GO:0021884) | 3.64721995 |
| 36 | regulation of metalloenzyme activity (GO:0048552) | 3.62362956 |
| 37 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 3.61005942 |
| 38 | cardiac left ventricle morphogenesis (GO:0003214) | 3.60031679 |
| 39 | amyloid precursor protein catabolic process (GO:0042987) | 3.58800851 |
| 40 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.58173439 |
| 41 | estrogen biosynthetic process (GO:0006703) | 3.57604943 |
| 42 | nonmotile primary cilium assembly (GO:0035058) | 3.53755416 |
| 43 | vagina development (GO:0060068) | 3.41460822 |
| 44 | negative regulation by host of viral transcription (GO:0043922) | 3.40485578 |
| 45 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.32757260 |
| 46 | ATP synthesis coupled proton transport (GO:0015986) | 3.32757260 |
| 47 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.31548531 |
| 48 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 3.30413111 |
| 49 | positive regulation of prostaglandin secretion (GO:0032308) | 3.28730854 |
| 50 | regulation of axon guidance (GO:1902667) | 3.27516896 |
| 51 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.25682317 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.25682317 |
| 53 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 3.24707868 |
| 54 | uterus development (GO:0060065) | 3.23128210 |
| 55 | transmission of nerve impulse (GO:0019226) | 3.22019790 |
| 56 | regulation of platelet aggregation (GO:0090330) | 3.20609417 |
| 57 | rRNA methylation (GO:0031167) | 3.20071826 |
| 58 | positive regulation of gastrulation (GO:2000543) | 3.20057230 |
| 59 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.19756516 |
| 60 | endocardial cushion morphogenesis (GO:0003203) | 3.19094388 |
| 61 | regulation of cGMP metabolic process (GO:0030823) | 3.18268920 |
| 62 | positive regulation of fatty acid transport (GO:2000193) | 3.17994913 |
| 63 | aorta morphogenesis (GO:0035909) | 3.16029933 |
| 64 | iron ion import (GO:0097286) | 3.15271678 |
| 65 | positive regulation of protein kinase C signaling (GO:0090037) | 3.14794562 |
| 66 | negative regulation of mast cell activation (GO:0033004) | 3.12648559 |
| 67 | response to gravity (GO:0009629) | 3.12382287 |
| 68 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 3.12050791 |
| 69 | negative regulation of axon extension (GO:0030517) | 3.06825384 |
| 70 | regulation of prostaglandin secretion (GO:0032306) | 3.01979429 |
| 71 | positive regulation of cGMP metabolic process (GO:0030825) | 3.01868409 |
| 72 | intracellular pH reduction (GO:0051452) | 2.99721291 |
| 73 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 2.99016876 |
| 74 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.98227655 |
| 75 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.98075280 |
| 76 | embryonic axis specification (GO:0000578) | 2.97898820 |
| 77 | cGMP biosynthetic process (GO:0006182) | 2.97478885 |
| 78 | trabecula morphogenesis (GO:0061383) | 2.97206845 |
| 79 | ventricular septum morphogenesis (GO:0060412) | 2.95901787 |
| 80 | regulation of cell maturation (GO:1903429) | 2.93255421 |
| 81 | establishment of tissue polarity (GO:0007164) | 2.93060402 |
| 82 | establishment of planar polarity (GO:0001736) | 2.93060402 |
| 83 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.87582921 |
| 84 | regulation of thymocyte apoptotic process (GO:0070243) | 2.86132443 |
| 85 | post-embryonic morphogenesis (GO:0009886) | 2.85861747 |
| 86 | type B pancreatic cell development (GO:0003323) | 2.83609959 |
| 87 | cardiac ventricle morphogenesis (GO:0003208) | 2.82047511 |
| 88 | heart trabecula formation (GO:0060347) | 2.81532529 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.81380137 |
| 90 | somitogenesis (GO:0001756) | 2.79370070 |
| 91 | ventricular cardiac muscle cell development (GO:0055015) | 2.79300021 |
| 92 | positive regulation of macrophage cytokine production (GO:0060907) | 2.78084198 |
| 93 | heart valve morphogenesis (GO:0003179) | 2.77900624 |
| 94 | maternal behavior (GO:0042711) | 2.77789382 |
| 95 | ganglion development (GO:0061548) | 2.76713679 |
| 96 | rRNA modification (GO:0000154) | 2.76195191 |
| 97 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.75496379 |
| 98 | convergent extension (GO:0060026) | 2.73781993 |
| 99 | regulation of transcription regulatory region DNA binding (GO:2000677) | 2.72217790 |
| 100 | histone mRNA catabolic process (GO:0071044) | 10.0918872 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 5.57326219 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.27413902 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.56268156 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.20134420 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.94437050 |
| 6 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.78790682 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.78779793 |
| 8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.77128662 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.34756876 |
| 10 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 2.06613701 |
| 11 | BCAT_22108803_ChIP-Seq_LS180_Human | 2.05994231 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.03763528 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.03638681 |
| 14 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.00460828 |
| 15 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.98034190 |
| 16 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.95514305 |
| 17 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.93390673 |
| 18 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.92887597 |
| 19 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.81756543 |
| 20 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.80220493 |
| 21 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.72359270 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.67699321 |
| 23 | RXR_22108803_ChIP-Seq_LS180_Human | 1.67645664 |
| 24 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.65674125 |
| 25 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.65499116 |
| 26 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.57241765 |
| 27 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.55105415 |
| 28 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.54475998 |
| 29 | TP53_16413492_ChIP-PET_HCT116_Human | 1.50454785 |
| 30 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.47652950 |
| 31 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.45464543 |
| 32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.45436877 |
| 33 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.44684494 |
| 34 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.44651078 |
| 35 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.44630386 |
| 36 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44505219 |
| 37 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.42855401 |
| 38 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.42855401 |
| 39 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.41443379 |
| 40 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.40422270 |
| 41 | AR_20517297_ChIP-Seq_VCAP_Human | 1.39003894 |
| 42 | ERA_21632823_ChIP-Seq_H3396_Human | 1.36495139 |
| 43 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36335689 |
| 44 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.35613220 |
| 45 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.33063953 |
| 46 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.33016271 |
| 47 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32576420 |
| 48 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32576420 |
| 49 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.32175932 |
| 50 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31637597 |
| 51 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.31479836 |
| 52 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.31420905 |
| 53 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.25976031 |
| 54 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.24116186 |
| 55 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.23288599 |
| 56 | GATA3_26560356_Chip-Seq_TH2_Human | 1.22339649 |
| 57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.20997538 |
| 58 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.18739012 |
| 59 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.17924515 |
| 60 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.17819595 |
| 61 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17536358 |
| 62 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.17185595 |
| 63 | CJUN_26792858_Chip-Seq_BT549_Human | 1.16640082 |
| 64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15694404 |
| 65 | CBP_21632823_ChIP-Seq_H3396_Human | 1.15099762 |
| 66 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.13404589 |
| 67 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.13333452 |
| 68 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13308384 |
| 69 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13072011 |
| 70 | STAT3_23295773_ChIP-Seq_U87_Human | 1.13020206 |
| 71 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.12809180 |
| 72 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.12645890 |
| 73 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.11611788 |
| 74 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.11487284 |
| 75 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.11162562 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09847610 |
| 77 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.09713359 |
| 78 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09429185 |
| 79 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.08396373 |
| 80 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.07641570 |
| 81 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.07211573 |
| 82 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.07163710 |
| 83 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.07158340 |
| 84 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.06777045 |
| 85 | P300_19829295_ChIP-Seq_ESCs_Human | 1.06369399 |
| 86 | SOX2_21211035_ChIP-Seq_LN229_Human | 1.05984140 |
| 87 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.05835472 |
| 88 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04821359 |
| 89 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.04564329 |
| 90 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.04025321 |
| 91 | TBL1_22424771_ChIP-Seq_293T_Human | 1.03723871 |
| 92 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01609558 |
| 93 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01609558 |
| 94 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.00886224 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.98783604 |
| 96 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98333458 |
| 97 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.97713810 |
| 98 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.97091243 |
| 99 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.97038504 |
| 100 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.96843387 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003890_abnormal_embryonic-extraembry | 7.63597901 |
| 2 | MP0004147_increased_porphyrin_level | 5.13563285 |
| 3 | MP0003011_delayed_dark_adaptation | 4.33961327 |
| 4 | MP0003252_abnormal_bile_duct | 3.09548227 |
| 5 | MP0006054_spinal_hemorrhage | 3.00646380 |
| 6 | MP0004145_abnormal_muscle_electrophysio | 2.93895133 |
| 7 | MP0003279_aneurysm | 2.76047628 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.67349543 |
| 9 | MP0009384_cardiac_valve_regurgitation | 2.58421335 |
| 10 | MP0002938_white_spotting | 2.31591005 |
| 11 | MP0008058_abnormal_DNA_repair | 2.19199585 |
| 12 | MP0002653_abnormal_ependyma_morphology | 2.16627056 |
| 13 | MP0002089_abnormal_postnatal_growth/wei | 2.14967068 |
| 14 | MP0003195_calcinosis | 2.09565093 |
| 15 | MP0009046_muscle_twitch | 1.97515179 |
| 16 | MP0003936_abnormal_reproductive_system | 1.87434130 |
| 17 | MP0005253_abnormal_eye_physiology | 1.85950932 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.84089127 |
| 19 | MP0008961_abnormal_basal_metabolism | 1.78214892 |
| 20 | MP0009053_abnormal_anal_canal | 1.68961869 |
| 21 | MP0000013_abnormal_adipose_tissue | 1.67762819 |
| 22 | MP0001986_abnormal_taste_sensitivity | 1.66395328 |
| 23 | MP0004043_abnormal_pH_regulation | 1.65758644 |
| 24 | MP0001529_abnormal_vocalization | 1.65726409 |
| 25 | MP0003123_paternal_imprinting | 1.64473492 |
| 26 | MP0001664_abnormal_digestion | 1.60548448 |
| 27 | MP0004142_abnormal_muscle_tone | 1.53975543 |
| 28 | MP0005085_abnormal_gallbladder_physiolo | 1.53813663 |
| 29 | MP0010368_abnormal_lymphatic_system | 1.51917438 |
| 30 | MP0000427_abnormal_hair_cycle | 1.50432225 |
| 31 | MP0000538_abnormal_urinary_bladder | 1.43235855 |
| 32 | MP0000343_altered_response_to | 1.42056114 |
| 33 | MP0002272_abnormal_nervous_system | 1.41408979 |
| 34 | MP0006138_congestive_heart_failure | 1.40262293 |
| 35 | MP0004019_abnormal_vitamin_homeostasis | 1.38644882 |
| 36 | MP0005084_abnormal_gallbladder_morpholo | 1.35013001 |
| 37 | MP0009745_abnormal_behavioral_response | 1.30867193 |
| 38 | MP0002282_abnormal_trachea_morphology | 1.27594791 |
| 39 | MP0001879_abnormal_lymphatic_vessel | 1.26515046 |
| 40 | MP0009379_abnormal_foot_pigmentation | 1.26091257 |
| 41 | MP0005330_cardiomyopathy | 1.23250532 |
| 42 | MP0004130_abnormal_muscle_cell | 1.22227780 |
| 43 | MP0008007_abnormal_cellular_replicative | 1.20802108 |
| 44 | MP0004085_abnormal_heartbeat | 1.20451886 |
| 45 | MP0005310_abnormal_salivary_gland | 1.18785140 |
| 46 | MP0008872_abnormal_physiological_respon | 1.17514762 |
| 47 | MP0008569_lethality_at_weaning | 1.13468658 |
| 48 | MP0008438_abnormal_cutaneous_collagen | 1.11837610 |
| 49 | MP0003937_abnormal_limbs/digits/tail_de | 1.10122416 |
| 50 | MP0008995_early_reproductive_senescence | 1.09162641 |
| 51 | MP0008875_abnormal_xenobiotic_pharmacok | 1.06413656 |
| 52 | MP0005595_abnormal_vascular_smooth | 1.05761551 |
| 53 | MP0002067_abnormal_sensory_capabilities | 1.04014230 |
| 54 | MP0005332_abnormal_amino_acid | 1.01358162 |
| 55 | MP0001501_abnormal_sleep_pattern | 1.01333479 |
| 56 | MP0002009_preneoplasia | 0.98120279 |
| 57 | MP0000569_abnormal_digit_pigmentation | 0.97568803 |
| 58 | MP0005266_abnormal_metabolism | 0.96168367 |
| 59 | MP0004133_heterotaxia | 0.95643928 |
| 60 | MP0010329_abnormal_lipoprotein_level | 0.93420433 |
| 61 | MP0002277_abnormal_respiratory_mucosa | 0.91863722 |
| 62 | MP0005171_absent_coat_pigmentation | 0.91433751 |
| 63 | MP0004883_abnormal_blood_vessel | 0.90826386 |
| 64 | MP0008932_abnormal_embryonic_tissue | 0.90160941 |
| 65 | MP0001853_heart_inflammation | 0.87694401 |
| 66 | MP0002928_abnormal_bile_duct | 0.86003121 |
| 67 | MP0002160_abnormal_reproductive_system | 0.84191450 |
| 68 | MP0000467_abnormal_esophagus_morphology | 0.84011404 |
| 69 | MP0003283_abnormal_digestive_organ | 0.80406103 |
| 70 | MP0005409_darkened_coat_color | 0.80143200 |
| 71 | MP0000003_abnormal_adipose_tissue | 0.79239506 |
| 72 | MP0005167_abnormal_blood-brain_barrier | 0.79183550 |
| 73 | MP0000230_abnormal_systemic_arterial | 0.78476137 |
| 74 | MP0003091_abnormal_cell_migration | 0.77623382 |
| 75 | MP0003950_abnormal_plasma_membrane | 0.77080454 |
| 76 | MP0003942_abnormal_urinary_system | 0.76921787 |
| 77 | MP0001119_abnormal_female_reproductive | 0.76429207 |
| 78 | MP0005376_homeostasis/metabolism_phenot | 0.74618624 |
| 79 | MP0008775_abnormal_heart_ventricle | 0.73638166 |
| 80 | MP0005164_abnormal_response_to | 0.73369396 |
| 81 | MP0002557_abnormal_social/conspecific_i | 0.71607188 |
| 82 | MP0005620_abnormal_muscle_contractility | 0.69279210 |
| 83 | MP0003191_abnormal_cellular_cholesterol | 0.68738799 |
| 84 | MP0005645_abnormal_hypothalamus_physiol | 0.68444545 |
| 85 | MP0008057_abnormal_DNA_replication | 0.68333830 |
| 86 | MP0005360_urolithiasis | 0.67674182 |
| 87 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.67241043 |
| 88 | MP0005391_vision/eye_phenotype | 0.66865449 |
| 89 | MP0002837_dystrophic_cardiac_calcinosis | 0.66370653 |
| 90 | MP0002064_seizures | 0.65051840 |
| 91 | MP0002751_abnormal_autonomic_nervous | 0.63553504 |
| 92 | MP0000762_abnormal_tongue_morphology | 0.63445756 |
| 93 | MP0002752_abnormal_somatic_nervous | 0.60624910 |
| 94 | MP0006276_abnormal_autonomic_nervous | 0.59949975 |
| 95 | MP0002210_abnormal_sex_determination | 0.59076386 |
| 96 | MP0003638_abnormal_response/metabolism_ | 0.56774820 |
| 97 | MP0002932_abnormal_joint_morphology | 0.55361884 |
| 98 | MP0005389_reproductive_system_phenotype | 0.54887853 |
| 99 | MP0002736_abnormal_nociception_after | 0.51316015 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.50619342 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 9.45954826 |
| 2 | Spastic paraparesis (HP:0002313) | 8.85741523 |
| 3 | Chromsome breakage (HP:0040012) | 8.27897397 |
| 4 | Congenital stationary night blindness (HP:0007642) | 5.65888973 |
| 5 | Paraparesis (HP:0002385) | 5.16166259 |
| 6 | Posterior subcapsular cataract (HP:0007787) | 5.05491320 |
| 7 | Medulloblastoma (HP:0002885) | 4.55217140 |
| 8 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.27604138 |
| 9 | Progressive inability to walk (HP:0002505) | 3.87719501 |
| 10 | Genetic anticipation (HP:0003743) | 3.72478602 |
| 11 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.57762992 |
| 12 | Meckel diverticulum (HP:0002245) | 3.54417671 |
| 13 | Abnormal biliary tract physiology (HP:0012439) | 3.48265424 |
| 14 | Bile duct proliferation (HP:0001408) | 3.48265424 |
| 15 | Embryonal renal neoplasm (HP:0011794) | 3.42185652 |
| 16 | Abnormality of the ileum (HP:0001549) | 3.36180911 |
| 17 | Abnormality of the preputium (HP:0100587) | 3.29729003 |
| 18 | Clubbing of toes (HP:0100760) | 3.28831239 |
| 19 | Emotional lability (HP:0000712) | 3.23066752 |
| 20 | Abnormality of chromosome stability (HP:0003220) | 2.92438098 |
| 21 | Pancytopenia (HP:0001876) | 2.85457693 |
| 22 | Neuroblastic tumors (HP:0004376) | 2.82172803 |
| 23 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 2.82172803 |
| 24 | Neuroblastoma (HP:0003006) | 2.82172803 |
| 25 | Primitive neuroectodermal tumor (HP:0030065) | 2.82172803 |
| 26 | Subcapsular cataract (HP:0000523) | 2.80582467 |
| 27 | Progressive cerebellar ataxia (HP:0002073) | 2.79880173 |
| 28 | Short middle phalanx of the 5th finger (HP:0004220) | 2.79159027 |
| 29 | Hemiparesis (HP:0001269) | 2.69819172 |
| 30 | Reticulocytopenia (HP:0001896) | 2.66377908 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.66072735 |
| 32 | Abnormality of midbrain morphology (HP:0002418) | 2.66072735 |
| 33 | Testicular atrophy (HP:0000029) | 2.63934052 |
| 34 | Birth length less than 3rd percentile (HP:0003561) | 2.62444137 |
| 35 | Inability to walk (HP:0002540) | 2.61419080 |
| 36 | Increased number of teeth (HP:0011069) | 2.56249903 |
| 37 | Scotoma (HP:0000575) | 2.44328554 |
| 38 | Abnormality of the carotid arteries (HP:0005344) | 2.43455440 |
| 39 | Abnormality of alanine metabolism (HP:0010916) | 2.32511029 |
| 40 | Hyperalaninemia (HP:0003348) | 2.32511029 |
| 41 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.32511029 |
| 42 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.30494235 |
| 43 | Pili torti (HP:0003777) | 2.29854688 |
| 44 | Horizontal nystagmus (HP:0000666) | 2.26965708 |
| 45 | Short thumb (HP:0009778) | 2.17294715 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.14973140 |
| 47 | Small intestinal stenosis (HP:0012848) | 2.11587720 |
| 48 | Duodenal stenosis (HP:0100867) | 2.11587720 |
| 49 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.10237179 |
| 50 | Concave nail (HP:0001598) | 2.08602379 |
| 51 | Embryonal neoplasm (HP:0002898) | 2.05984735 |
| 52 | Attenuation of retinal blood vessels (HP:0007843) | 2.04631976 |
| 53 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.02398358 |
| 54 | Duplicated collecting system (HP:0000081) | 2.02156130 |
| 55 | Astigmatism (HP:0000483) | 2.02022207 |
| 56 | Aplastic anemia (HP:0001915) | 10.3830487 |
| 57 | Arthropathy (HP:0003040) | 1.99831279 |
| 58 | Triphalangeal thumb (HP:0001199) | 1.99438299 |
| 59 | Pendular nystagmus (HP:0012043) | 1.97297876 |
| 60 | Secondary amenorrhea (HP:0000869) | 1.95448249 |
| 61 | Azoospermia (HP:0000027) | 1.95426502 |
| 62 | Hyperglycinuria (HP:0003108) | 1.94869323 |
| 63 | Abnormality of the duodenum (HP:0002246) | 1.93826376 |
| 64 | Sex reversal (HP:0012245) | 1.91299123 |
| 65 | Abnormal sex determination (HP:0012244) | 1.91299123 |
| 66 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.90347538 |
| 67 | Mesomelia (HP:0003027) | 1.89419546 |
| 68 | Short 5th finger (HP:0009237) | 1.86835092 |
| 69 | Vacuolated lymphocytes (HP:0001922) | 1.84796599 |
| 70 | Abnormal gallbladder physiology (HP:0012438) | 1.84486163 |
| 71 | Cholecystitis (HP:0001082) | 1.84486163 |
| 72 | Breast hypoplasia (HP:0003187) | 1.83808310 |
| 73 | Abnormality of the renal collecting system (HP:0004742) | 1.80700456 |
| 74 | Abnormality of abdominal situs (HP:0011620) | 1.79446550 |
| 75 | Abdominal situs inversus (HP:0003363) | 1.79446550 |
| 76 | Macular degeneration (HP:0000608) | 1.79429063 |
| 77 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.78052707 |
| 78 | Brushfield spots (HP:0001088) | 1.76696207 |
| 79 | Nervous tissue neoplasm (HP:0030060) | 1.75971196 |
| 80 | Neuroectodermal neoplasm (HP:0030061) | 1.75971196 |
| 81 | Neuroepithelial neoplasm (HP:0030063) | 1.75971196 |
| 82 | Type II lissencephaly (HP:0007260) | 1.75906926 |
| 83 | Myotonia (HP:0002486) | 1.75814600 |
| 84 | Confusion (HP:0001289) | 1.74754386 |
| 85 | Hypoplastic labia majora (HP:0000059) | 1.73282043 |
| 86 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.73069304 |
| 87 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.71478268 |
| 88 | Arteriovenous malformation (HP:0100026) | 1.70692086 |
| 89 | Abnormal drinking behavior (HP:0030082) | 1.69078642 |
| 90 | Polydipsia (HP:0001959) | 1.69078642 |
| 91 | True hermaphroditism (HP:0010459) | 1.67422182 |
| 92 | Congenital, generalized hypertrichosis (HP:0004540) | 1.66518035 |
| 93 | Polyuria (HP:0000103) | 1.64038998 |
| 94 | Female pseudohermaphroditism (HP:0010458) | 1.62349234 |
| 95 | Spastic tetraparesis (HP:0001285) | 1.61336139 |
| 96 | Neonatal respiratory distress (HP:0002643) | 1.61135399 |
| 97 | Abnormal hair laboratory examination (HP:0003328) | 1.58017363 |
| 98 | Medial flaring of the eyebrow (HP:0010747) | 1.57635070 |
| 99 | Long nose (HP:0003189) | 1.56301438 |
| 100 | Renal duplication (HP:0000075) | 1.56276252 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK1 | 7.13246225 |
| 2 | TSSK6 | 4.55840001 |
| 3 | NME1 | 3.44215463 |
| 4 | EIF2AK1 | 2.85613133 |
| 5 | PASK | 2.61896328 |
| 6 | STK39 | 2.57943151 |
| 7 | WNK4 | 2.47093768 |
| 8 | DYRK3 | 2.45631575 |
| 9 | ADRBK2 | 2.41235494 |
| 10 | STK38L | 2.38557663 |
| 11 | TGFBR1 | 2.30363250 |
| 12 | BRSK2 | 2.29887379 |
| 13 | CAMKK2 | 2.22385909 |
| 14 | MAPK15 | 2.21540079 |
| 15 | ACVR1B | 2.11291868 |
| 16 | MAPKAPK3 | 2.07188031 |
| 17 | ERN1 | 2.04761314 |
| 18 | BMPR1B | 1.98764844 |
| 19 | EPHB2 | 1.97655292 |
| 20 | MKNK2 | 1.75542725 |
| 21 | EIF2AK3 | 1.75131588 |
| 22 | BRSK1 | 1.63856559 |
| 23 | FRK | 1.61003711 |
| 24 | WNK3 | 1.56386776 |
| 25 | OXSR1 | 1.52787514 |
| 26 | WEE1 | 1.49694231 |
| 27 | TAOK3 | 1.44575064 |
| 28 | STK24 | 1.36473992 |
| 29 | MAP3K10 | 1.32294877 |
| 30 | MST4 | 1.22645235 |
| 31 | ADRBK1 | 1.18043493 |
| 32 | ABL2 | 1.13693542 |
| 33 | MAP3K9 | 1.12645270 |
| 34 | BCKDK | 1.10110618 |
| 35 | STK3 | 1.06805052 |
| 36 | BMX | 1.02652301 |
| 37 | KIT | 1.01605448 |
| 38 | MKNK1 | 0.98685590 |
| 39 | NEK6 | 0.90087228 |
| 40 | GRK5 | 0.86351053 |
| 41 | CAMKK1 | 0.86305062 |
| 42 | ZAK | 0.86070145 |
| 43 | VRK2 | 0.85803943 |
| 44 | CHUK | 0.81907006 |
| 45 | IKBKB | 0.80382797 |
| 46 | TNK2 | 0.79709675 |
| 47 | MAP3K4 | 0.78792737 |
| 48 | MAPK13 | 0.76826493 |
| 49 | KSR1 | 0.73375310 |
| 50 | MAP4K2 | 0.71029785 |
| 51 | PRKD2 | 0.67630781 |
| 52 | NEK2 | 0.66939525 |
| 53 | VRK1 | 0.63963292 |
| 54 | PRKCI | 0.62455779 |
| 55 | MAP2K1 | 0.60076357 |
| 56 | MAP2K7 | 0.59659210 |
| 57 | STK16 | 0.55084406 |
| 58 | MUSK | 0.54263461 |
| 59 | DYRK1A | 0.52378997 |
| 60 | BMPR2 | 0.50303406 |
| 61 | MAP3K2 | 0.48865861 |
| 62 | PAK3 | 0.45798563 |
| 63 | MAPKAPK5 | 0.44232134 |
| 64 | CAMK1D | 0.43944564 |
| 65 | NEK1 | 0.43383774 |
| 66 | TLK1 | 0.43010814 |
| 67 | CSNK1G3 | 0.41430245 |
| 68 | PLK3 | 0.41409971 |
| 69 | SGK3 | 0.41079852 |
| 70 | PTK2B | 0.40202213 |
| 71 | CSNK1A1L | 0.39464878 |
| 72 | STK11 | 0.38888722 |
| 73 | SGK2 | 0.34566626 |
| 74 | RPS6KA1 | 0.34435839 |
| 75 | GRK7 | 0.34382937 |
| 76 | PLK1 | 0.32987850 |
| 77 | IRAK3 | 0.32513350 |
| 78 | PRKCQ | 0.31395570 |
| 79 | STK10 | 0.31095740 |
| 80 | CSNK1G2 | 0.30294179 |
| 81 | RPS6KA5 | 0.29552336 |
| 82 | CDK3 | 0.27714868 |
| 83 | INSRR | 0.26153559 |
| 84 | CSNK1D | 0.26114723 |
| 85 | SGK223 | 0.25510261 |
| 86 | SGK494 | 0.25510261 |
| 87 | MAP2K4 | 0.24957480 |
| 88 | PRKCG | 0.24430880 |
| 89 | PLK2 | 0.23524297 |
| 90 | PIK3CA | 0.23114833 |
| 91 | PINK1 | 0.22977579 |
| 92 | PRKD3 | 0.20882079 |
| 93 | RPS6KB2 | 0.20486428 |
| 94 | CSNK2A2 | 0.20402571 |
| 95 | KDR | 0.20142828 |
| 96 | ARAF | 0.18788794 |
| 97 | PRKACA | 0.16597721 |
| 98 | PIK3CG | 0.15022669 |
| 99 | ERBB2 | 0.14283250 |
| 100 | CSNK1G1 | 0.13930516 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 7.13963508 |
| 2 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 3.66283206 |
| 3 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 3.49260469 |
| 4 | Phototransduction_Homo sapiens_hsa04744 | 3.05693319 |
| 5 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.90796224 |
| 6 | Basal transcription factors_Homo sapiens_hsa03022 | 2.75903393 |
| 7 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.74638492 |
| 8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.12131143 |
| 9 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.89591606 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 1.89480719 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.85708263 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.78093745 |
| 13 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.72145326 |
| 14 | Mineral absorption_Homo sapiens_hsa04978 | 1.59198112 |
| 15 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.58712182 |
| 16 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.58553328 |
| 17 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.57281150 |
| 18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.56377631 |
| 19 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.54816671 |
| 20 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.46502484 |
| 21 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.38850332 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.34157289 |
| 23 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.29619846 |
| 24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.28694134 |
| 25 | Sulfur relay system_Homo sapiens_hsa04122 | 1.25895250 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.24195951 |
| 27 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.23048056 |
| 28 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.20428915 |
| 29 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.16419972 |
| 30 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.14355786 |
| 31 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.13163722 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.11158739 |
| 33 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.09697694 |
| 34 | Parkinsons disease_Homo sapiens_hsa05012 | 1.08994704 |
| 35 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.04431758 |
| 36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.03742361 |
| 37 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.02099706 |
| 38 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.99004042 |
| 39 | Histidine metabolism_Homo sapiens_hsa00340 | 0.97714861 |
| 40 | Tight junction_Homo sapiens_hsa04530 | 0.95195900 |
| 41 | Morphine addiction_Homo sapiens_hsa05032 | 0.93903243 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92435537 |
| 43 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92283230 |
| 44 | ABC transporters_Homo sapiens_hsa02010 | 0.91367387 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.86531609 |
| 46 | Taste transduction_Homo sapiens_hsa04742 | 0.85244380 |
| 47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.84160048 |
| 48 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.81184684 |
| 49 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.79392494 |
| 50 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.79080973 |
| 51 | Salivary secretion_Homo sapiens_hsa04970 | 0.74657139 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.72918699 |
| 53 | Homologous recombination_Homo sapiens_hsa03440 | 0.72508345 |
| 54 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.69770488 |
| 55 | Circadian entrainment_Homo sapiens_hsa04713 | 0.69546532 |
| 56 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.69196869 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68976994 |
| 58 | GABAergic synapse_Homo sapiens_hsa04727 | 0.67325422 |
| 59 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.66484977 |
| 60 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.65234697 |
| 61 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.64011943 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63854158 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.59387922 |
| 64 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.58956079 |
| 65 | Peroxisome_Homo sapiens_hsa04146 | 0.56843269 |
| 66 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56634602 |
| 67 | Legionellosis_Homo sapiens_hsa05134 | 0.56122888 |
| 68 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.55100596 |
| 69 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54198405 |
| 70 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.53118393 |
| 71 | Long-term depression_Homo sapiens_hsa04730 | 0.52849824 |
| 72 | Huntingtons disease_Homo sapiens_hsa05016 | 0.52656039 |
| 73 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.52550076 |
| 74 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.51553240 |
| 75 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.46867465 |
| 76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46309679 |
| 77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41046707 |
| 78 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.40137390 |
| 79 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.36848299 |
| 80 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.36543540 |
| 81 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35977509 |
| 82 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.35137275 |
| 83 | Renin secretion_Homo sapiens_hsa04924 | 0.34859315 |
| 84 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.34151273 |
| 85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.33159539 |
| 86 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.31756734 |
| 87 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.31752669 |
| 88 | RNA polymerase_Homo sapiens_hsa03020 | 0.31589458 |
| 89 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.31320968 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30315416 |
| 91 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.30277161 |
| 92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.30081000 |
| 93 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29401925 |
| 94 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.28829265 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27480087 |
| 96 | Metabolic pathways_Homo sapiens_hsa01100 | 0.27115997 |
| 97 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.25642520 |
| 98 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.25559112 |
| 99 | Prion diseases_Homo sapiens_hsa05020 | 0.23916266 |
| 100 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.23133282 |

