EXOSC10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.09194897
2protein localization to kinetochore (GO:0034501)4.80643351
3nuclear pore complex assembly (GO:0051292)4.74755848
4nuclear pore organization (GO:0006999)4.65615148
5DNA strand elongation involved in DNA replication (GO:0006271)4.56744873
6formation of translation preinitiation complex (GO:0001731)4.43886883
7DNA replication initiation (GO:0006270)4.38126093
8DNA strand elongation (GO:0022616)4.33852943
9telomere maintenance via semi-conservative replication (GO:0032201)4.16729831
10protein localization to chromosome, centromeric region (GO:0071459)4.14458176
11mitotic nuclear envelope disassembly (GO:0007077)4.11691047
12negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.07234844
13DNA replication checkpoint (GO:0000076)4.06253440
14establishment of integrated proviral latency (GO:0075713)4.05203416
15IMP biosynthetic process (GO:0006188)4.03044660
16ribosome assembly (GO:0042255)3.91695073
17nucleobase biosynthetic process (GO:0046112)3.87119608
18telomere maintenance via recombination (GO:0000722)3.85198522
19non-recombinational repair (GO:0000726)3.83618481
20double-strand break repair via nonhomologous end joining (GO:0006303)3.83618481
21membrane disassembly (GO:0030397)3.81445785
22nuclear envelope disassembly (GO:0051081)3.81445785
23mitotic recombination (GO:0006312)3.79493601
24ribosome biogenesis (GO:0042254)3.79149138
25DNA replication-dependent nucleosome organization (GO:0034723)3.75705694
26DNA replication-dependent nucleosome assembly (GO:0006335)3.75705694
27DNA duplex unwinding (GO:0032508)3.73909608
28DNA geometric change (GO:0032392)3.71459923
29negative regulation of RNA splicing (GO:0033119)3.66155733
30mitotic sister chromatid segregation (GO:0000070)3.64833246
31mitotic chromosome condensation (GO:0007076)3.59611542
32sister chromatid segregation (GO:0000819)3.58953778
33pore complex assembly (GO:0046931)3.56578189
34translesion synthesis (GO:0019985)3.54167134
35folic acid-containing compound biosynthetic process (GO:0009396)3.52669222
36viral mRNA export from host cell nucleus (GO:0046784)3.52229408
37purine nucleobase biosynthetic process (GO:0009113)3.49504175
38IMP metabolic process (GO:0046040)3.41989029
39DNA ligation (GO:0006266)3.38248933
40negative regulation of mRNA processing (GO:0050686)3.36068772
41telomere maintenance via telomere lengthening (GO:0010833)3.34634332
42mitotic metaphase plate congression (GO:0007080)3.34271819
43ribosomal small subunit assembly (GO:0000028)3.33718684
44maturation of SSU-rRNA (GO:0030490)3.30574962
45kinetochore organization (GO:0051383)3.29582639
46establishment of viral latency (GO:0019043)3.25569636
47pseudouridine synthesis (GO:0001522)3.24970953
48postreplication repair (GO:0006301)3.24574754
49regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.23731915
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.23729436
51meiotic chromosome segregation (GO:0045132)3.22731556
52regulation of spindle organization (GO:0090224)3.19558940
53DNA replication-independent nucleosome organization (GO:0034724)3.18748389
54DNA replication-independent nucleosome assembly (GO:0006336)3.18748389
55regulation of double-strand break repair via homologous recombination (GO:0010569)3.18328739
56nucleotide-excision repair, DNA gap filling (GO:0006297)3.18094021
57regulation of translational fidelity (GO:0006450)3.17308780
58negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.15847556
59DNA conformation change (GO:0071103)3.15297393
60attachment of spindle microtubules to kinetochore (GO:0008608)3.15101530
61tRNA aminoacylation for protein translation (GO:0006418)3.12327128
62DNA catabolic process, exonucleolytic (GO:0000738)3.12314742
63ribonucleoprotein complex biogenesis (GO:0022613)3.11603158
64negative regulation of chromosome segregation (GO:0051985)3.11222908
65chromatin remodeling at centromere (GO:0031055)3.10745395
66amino acid activation (GO:0043038)3.10532324
67tRNA aminoacylation (GO:0043039)3.10532324
68anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.10295945
69replication fork processing (GO:0031297)3.09920096
70maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.09271332
71RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.09086625
72mRNA splicing, via spliceosome (GO:0000398)3.09086625
73regulation of sister chromatid cohesion (GO:0007063)3.07569080
74termination of RNA polymerase II transcription (GO:0006369)3.07370905
75RNA splicing, via transesterification reactions (GO:0000375)3.07144583
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.07066906
77regulation of DNA endoreduplication (GO:0032875)3.06506454
78CENP-A containing nucleosome assembly (GO:0034080)3.06483809
79negative regulation of histone methylation (GO:0031061)3.05224738
80chromatin assembly or disassembly (GO:0006333)3.04953760
81DNA topological change (GO:0006265)3.04652757
82regulation of chromosome segregation (GO:0051983)3.04402497
83spindle assembly checkpoint (GO:0071173)3.03250081
84negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.02837241
85negative regulation of sister chromatid segregation (GO:0033046)3.02837241
86negative regulation of mitotic sister chromatid separation (GO:2000816)3.02837241
87negative regulation of mitotic sister chromatid segregation (GO:0033048)3.02837241
88RNA export from nucleus (GO:0006405)3.02607021
89nuclear envelope organization (GO:0006998)3.02044915
90heterochromatin organization (GO:0070828)3.01248826
91chromosome segregation (GO:0007059)3.00303211
92mRNA export from nucleus (GO:0006406)2.99947036
93regulation of histone H3-K9 methylation (GO:0051570)2.98747003
94positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.98628183
95mitotic spindle assembly checkpoint (GO:0007094)2.98598804
96somatic diversification of immune receptors via somatic mutation (GO:0002566)2.98554822
97somatic hypermutation of immunoglobulin genes (GO:0016446)2.98554822
98mRNA transport (GO:0051028)2.98342518
99kinetochore assembly (GO:0051382)2.97703264
100transcription-coupled nucleotide-excision repair (GO:0006283)2.97503785
101* dosage compensation (GO:0007549)2.97336502
102spliceosomal tri-snRNP complex assembly (GO:0000244)2.95698493
103mitotic sister chromatid cohesion (GO:0007064)2.95517926
104negative regulation of ligase activity (GO:0051352)2.95031237
105negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.95031237
106regulation of mitochondrial translation (GO:0070129)2.94039671
107negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.93780997
108mitochondrial RNA metabolic process (GO:0000959)2.93769990
109peptidyl-arginine omega-N-methylation (GO:0035247)2.91667588
110positive regulation of chromosome segregation (GO:0051984)2.91419140
111negative regulation of mRNA metabolic process (GO:1903312)2.89871651
112chromosome condensation (GO:0030261)2.89620240
113metaphase plate congression (GO:0051310)2.88164880
114protein localization to chromosome (GO:0034502)2.87715423
115mitotic cell cycle (GO:0000278)2.87557708
116regulation of mitotic metaphase/anaphase transition (GO:0030071)2.87329595
117spindle checkpoint (GO:0031577)2.85346336
118intra-S DNA damage checkpoint (GO:0031573)2.83753338
119base-excision repair (GO:0006284)2.82631258
120resolution of meiotic recombination intermediates (GO:0000712)2.82006298
121regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.80684035
122G1/S transition of mitotic cell cycle (GO:0000082)2.79152857
123mitotic spindle checkpoint (GO:0071174)2.78805807
124regulation of mitotic sister chromatid segregation (GO:0033047)2.78482121
125regulation of sister chromatid segregation (GO:0033045)2.78482121
126regulation of mitotic sister chromatid separation (GO:0010965)2.78482121
127pre-miRNA processing (GO:0031054)2.77030579
128histone H2A acetylation (GO:0043968)2.76662475
129telomere maintenance (GO:0000723)2.76065898
130telomere organization (GO:0032200)2.75181975
131ATP-dependent chromatin remodeling (GO:0043044)2.75154770
132establishment of chromosome localization (GO:0051303)2.74408330

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.95911057
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.48800649
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.83299753
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.62076721
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.47499933
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97604942
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.76931939
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.72941300
9MYC_22102868_ChIP-Seq_BL_Human2.65052047
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.55593596
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.44113166
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.28102521
13XRN2_22483619_ChIP-Seq_HELA_Human2.21846785
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.19584371
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.16793381
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.16586922
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14188615
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.06344168
19CIITA_25753668_ChIP-Seq_RAJI_Human1.97635349
20E2F1_21310950_ChIP-Seq_MCF-7_Human1.92439000
21* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.89181005
22AR_21909140_ChIP-Seq_LNCAP_Human1.88219683
23GABP_17652178_ChIP-ChIP_JURKAT_Human1.80738926
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80482789
25MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79209466
26KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.77272679
27FOXP3_21729870_ChIP-Seq_TREG_Human1.76138448
28VDR_23849224_ChIP-Seq_CD4+_Human1.73749708
29CREB1_15753290_ChIP-ChIP_HEK293T_Human1.73673249
30VDR_21846776_ChIP-Seq_THP-1_Human1.68336869
31TTF2_22483619_ChIP-Seq_HELA_Human1.67245997
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.65972067
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.65841944
34* GABP_19822575_ChIP-Seq_HepG2_Human1.65664445
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.64816025
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63304585
37* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.61916184
38DCP1A_22483619_ChIP-Seq_HELA_Human1.60317599
39* KDM5A_27292631_Chip-Seq_BREAST_Human1.59374285
40PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.59116528
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.58454059
42CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.57275172
43* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56757619
44TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.55610864
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54594825
46ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52497962
47TP63_19390658_ChIP-ChIP_HaCaT_Human1.52243232
48SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.49473934
49CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.49137068
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49065216
51NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44378292
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.40203553
53STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39181669
54CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36387654
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.34875309
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.33974836
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.33837911
58NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.32277679
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31218841
60PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.27854998
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.27342103
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26345570
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24725790
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24515052
65DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24382973
66DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.23538975
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.23071732
68MYC_18940864_ChIP-ChIP_HL60_Human1.22960238
69KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22788687
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.18050470
71TFEB_21752829_ChIP-Seq_HELA_Human1.17637306
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.16800304
73* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.16301022
74* ELK1_19687146_ChIP-ChIP_HELA_Human1.15636755
75SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13801958
76CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12976745
77* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.11443327
78FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09614206
79HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09094146
80MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08236129
81ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07953947
82* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.07510022
83KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04278147
84* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04065633
85CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.02813639
86NANOG_21062744_ChIP-ChIP_HESCs_Human1.02627625
87* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01195465
88TCF7_22412390_ChIP-Seq_EML_Mouse1.00253361
89POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96831106
90ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96676736
91UTX_26944678_Chip-Seq_JUKART_Human0.95846609
92* MAF_26560356_Chip-Seq_TH1_Human0.95548730
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93580182
94SRF_21415370_ChIP-Seq_HL-1_Mouse0.91518603
95PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90161910
96MYB_26560356_Chip-Seq_TH1_Human0.89281973
97TBX5_21415370_ChIP-Seq_HL-1_Mouse0.88733116
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88383094
99* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.87801295
100SPI1_23547873_ChIP-Seq_NB4_Human0.87064080
101CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.86771634
102SALL1_21062744_ChIP-ChIP_HESCs_Human0.86097316
103ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.84569593
104ELK3_25401928_ChIP-Seq_HUVEC_Human0.83356794
105BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82801389
106KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.82424798
107* MAF_26560356_Chip-Seq_TH2_Human0.80263625
108ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.80057390
109MYB_26560356_Chip-Seq_TH2_Human0.78884034
110CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.78749765
111RUNX1_22412390_ChIP-Seq_EML_Mouse0.78406684
112TCF3_18692474_ChIP-Seq_MEFs_Mouse0.78312734
113PKCTHETA_26484144_Chip-Seq_BREAST_Human0.72245769
114CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71686905
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70651081
116TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.70504155
117NCOR1_26117541_ChIP-Seq_K562_Human0.70143103
118FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69475493
119SOX17_20123909_ChIP-Seq_XEN_Mouse0.68426935
120FOXP1_21924763_ChIP-Seq_HESCs_Human0.66802916
121SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.66604056
122CHD1_26751641_Chip-Seq_LNCaP_Human0.64233723

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology4.31096187
2MP0003693_abnormal_embryo_hatching4.15184471
3MP0010094_abnormal_chromosome_stability4.14823738
4MP0008057_abnormal_DNA_replication3.74279179
5MP0004957_abnormal_blastocyst_morpholog3.71533980
6MP0003077_abnormal_cell_cycle3.64550137
7MP0009697_abnormal_copulation2.94309236
8MP0002396_abnormal_hematopoietic_system2.78094622
9MP0008058_abnormal_DNA_repair2.69684216
10MP0008007_abnormal_cellular_replicative2.65499818
11MP0010352_gastrointestinal_tract_polyps2.62736636
12MP0003806_abnormal_nucleotide_metabolis2.57139138
13MP0001730_embryonic_growth_arrest2.45357511
14MP0000350_abnormal_cell_proliferation2.32776729
15MP0008877_abnormal_DNA_methylation2.25945227
16MP0003123_paternal_imprinting2.19005486
17MP0004147_increased_porphyrin_level2.17728092
18MP0008932_abnormal_embryonic_tissue2.17385452
19MP0001672_abnormal_embryogenesis/_devel1.97199655
20MP0005380_embryogenesis_phenotype1.97199655
21MP0004808_abnormal_hematopoietic_stem1.86540833
22MP0003984_embryonic_growth_retardation1.85131154
23MP0005076_abnormal_cell_differentiation1.81221210
24MP0002088_abnormal_embryonic_growth/wei1.81195904
25MP0001697_abnormal_embryo_size1.81179886
26MP0010307_abnormal_tumor_latency1.78844841
27MP0003763_abnormal_thymus_physiology1.75030122
28MP0002080_prenatal_lethality1.70540450
29MP0002085_abnormal_embryonic_tissue1.67144142
30MP0006035_abnormal_mitochondrial_morpho1.66767846
31MP0004197_abnormal_fetal_growth/weight/1.65549537
32MP0002084_abnormal_developmental_patter1.65428285
33MP0002653_abnormal_ependyma_morphology1.63669692
34MP0000490_abnormal_crypts_of1.57890806
35MP0003786_premature_aging1.57740688
36MP0002086_abnormal_extraembryonic_tissu1.52884142
37MP0010030_abnormal_orbit_morphology1.50968276
38MP0000313_abnormal_cell_death1.48256098
39MP0002019_abnormal_tumor_incidence1.47369649
40MP0000703_abnormal_thymus_morphology1.45268247
41MP0002398_abnormal_bone_marrow1.41373619
42MP0003121_genomic_imprinting1.41077587
43MP0009278_abnormal_bone_marrow1.39212121
44MP0009333_abnormal_splenocyte_physiolog1.36889263
45MP0005397_hematopoietic_system_phenotyp1.34810497
46MP0001545_abnormal_hematopoietic_system1.34810497
47MP0006292_abnormal_olfactory_placode1.30598482
48MP0003567_abnormal_fetal_cardiomyocyte1.24365980
49MP0002722_abnormal_immune_system1.21331922
50MP0006036_abnormal_mitochondrial_physio1.19172457
51MP0002877_abnormal_melanocyte_morpholog1.19010233
52MP0003890_abnormal_embryonic-extraembry1.14372713
53MP0000689_abnormal_spleen_morphology1.13724598
54MP0002009_preneoplasia1.11172894
55MP0005023_abnormal_wound_healing1.09616002
56MP0003656_abnormal_erythrocyte_physiolo1.09118474
57MP0004233_abnormal_muscle_weight1.08162682
58MP0009053_abnormal_anal_canal1.08144086
59MP0003315_abnormal_perineum_morphology1.07958363
60MP0001293_anophthalmia1.07561457
61MP0002210_abnormal_sex_determination1.07054148
62MP0001849_ear_inflammation1.04193044
63MP0002429_abnormal_blood_cell1.03939154
64MP0001661_extended_life_span1.03400628
65MP0000685_abnormal_immune_system1.02953143
66MP0003186_abnormal_redox_activity1.00585482
67MP0008995_early_reproductive_senescence0.99534728
68MP0000428_abnormal_craniofacial_morphol0.99488652
69MP0001145_abnormal_male_reproductive0.97311803
70MP0003705_abnormal_hypodermis_morpholog0.97253270
71MP0009672_abnormal_birth_weight0.94715517
72MP0001929_abnormal_gametogenesis0.94689169
73MP0003119_abnormal_digestive_system0.93627702
74MP0002160_abnormal_reproductive_system0.93477464
75MP0000716_abnormal_immune_system0.93276606
76MP0000858_altered_metastatic_potential0.93010196
77MP0001764_abnormal_homeostasis0.92568685
78MP0004264_abnormal_extraembryonic_tissu0.90114087
79MP0001915_intracranial_hemorrhage0.89727683
80MP0002006_tumorigenesis0.89250119
81MP0001800_abnormal_humoral_immune0.84104091
82MP0002925_abnormal_cardiovascular_devel0.82185109
83MP0002269_muscular_atrophy0.81916255
84MP0005384_cellular_phenotype0.80602728
85MP0002970_abnormal_white_adipose0.80522278
86MP0008789_abnormal_olfactory_epithelium0.79362960
87MP0005621_abnormal_cell_physiology0.79184886
88MP0000537_abnormal_urethra_morphology0.78870055
89MP0003221_abnormal_cardiomyocyte_apopto0.78740142
90MP0000653_abnormal_sex_gland0.78611473
91MP0000358_abnormal_cell_content/0.78216187
92MP0005670_abnormal_white_adipose0.77364153
93MP0000733_abnormal_muscle_development0.75547301
94MP0003566_abnormal_cell_adhesion0.73819552
95MP0003646_muscle_fatigue0.73126662
96MP0002697_abnormal_eye_size0.73036333
97MP0003943_abnormal_hepatobiliary_system0.72499267
98MP0002405_respiratory_system_inflammati0.72263860
99MP0009703_decreased_birth_body0.71952887
100MP0003115_abnormal_respiratory_system0.71888298
101MP0004133_heterotaxia0.71675877
102MP0004084_abnormal_cardiac_muscle0.70746338
103MP0002092_abnormal_eye_morphology0.70472954
104MP0000465_gastrointestinal_hemorrhage0.69831211
105MP0003698_abnormal_male_reproductive0.69825604
106MP0008770_decreased_survivor_rate0.69320717
107MP0000266_abnormal_heart_morphology0.69169273
108MP0001119_abnormal_female_reproductive0.69138674
109MP0002420_abnormal_adaptive_immunity0.68092457
110MP0003718_maternal_effect0.67810506
111MP0005671_abnormal_response_to0.67228551
112MP0005389_reproductive_system_phenotype0.66965981
113MP0005394_taste/olfaction_phenotype0.66918956
114MP0005499_abnormal_olfactory_system0.66918956
115MP0005501_abnormal_skin_physiology0.66218622
116MP0001819_abnormal_immune_cell0.66081089
117MP0005395_other_phenotype0.65922030
118MP0005075_abnormal_melanosome_morpholog0.65685965
119MP0003861_abnormal_nervous_system0.65512381
120MP0003937_abnormal_limbs/digits/tail_de0.64285178
121MP0001727_abnormal_embryo_implantation0.63585700
122MP0000750_abnormal_muscle_regeneration0.63544714
123MP0000477_abnormal_intestine_morphology0.63510701
124MP0003935_abnormal_craniofacial_develop0.63124447
125MP0002111_abnormal_tail_morphology0.61641880
126MP0000372_irregular_coat_pigmentation0.58287270
127MP0005408_hypopigmentation0.57706941
128MP0002161_abnormal_fertility/fecundity0.56487799
129MP0002102_abnormal_ear_morphology0.55199625
130MP0003699_abnormal_female_reproductive0.53444182
131MP0005266_abnormal_metabolism0.48392148
132MP0000598_abnormal_liver_morphology0.47118402
133MP0001853_heart_inflammation0.43915391
134MP0001270_distended_abdomen0.42532352
135MP0008873_increased_physiological_sensi0.42134742
136MP0002166_altered_tumor_susceptibility0.41983358

Predicted human phenotypes

RankGene SetZ-score
1Microvesicular hepatic steatosis (HP:0001414)4.12275421
2Type I transferrin isoform profile (HP:0003642)4.03369994
3Reduced antithrombin III activity (HP:0001976)3.81386416
4Abnormal protein glycosylation (HP:0012346)3.80207549
5Abnormal glycosylation (HP:0012345)3.80207549
6Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.80207549
7Abnormal protein N-linked glycosylation (HP:0012347)3.80207549
8Abnormality of DNA repair (HP:0003254)3.80015351
9Selective tooth agenesis (HP:0001592)3.77292418
10Birth length less than 3rd percentile (HP:0003561)3.66347205
11Abnormal number of incisors (HP:0011064)3.35946339
12Ependymoma (HP:0002888)3.30819372
13Poikiloderma (HP:0001029)3.21230553
14Entropion (HP:0000621)3.20672937
15Medulloblastoma (HP:0002885)2.98671453
16Chromsome breakage (HP:0040012)2.93598436
17Reticulocytopenia (HP:0001896)2.89763958
18Abnormality of the anterior horn cell (HP:0006802)2.82426320
19Degeneration of anterior horn cells (HP:0002398)2.82426320
20Colon cancer (HP:0003003)2.78615554
21Patellar aplasia (HP:0006443)2.75670994
22Chromosomal breakage induced by crosslinking agents (HP:0003221)2.67910364
23Short 4th metacarpal (HP:0010044)2.66287592
24Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.66287592
25Prominent nose (HP:0000448)2.65409675
26Bicuspid aortic valve (HP:0001647)2.64202322
27Myelodysplasia (HP:0002863)2.64043550
28Oral leukoplakia (HP:0002745)2.62094890
29Increased nuchal translucency (HP:0010880)2.61739837
30Aplasia/Hypoplasia of the patella (HP:0006498)2.57531361
31Abnormal number of erythroid precursors (HP:0012131)2.56921876
32Progressive muscle weakness (HP:0003323)2.56421359
33Breast hypoplasia (HP:0003187)2.54511455
34Abnormality of cells of the erythroid lineage (HP:0012130)2.54394077
35Poor head control (HP:0002421)2.54220977
3611 pairs of ribs (HP:0000878)2.53488428
37Basal cell carcinoma (HP:0002671)2.50212918
38Pancytopenia (HP:0001876)2.49940776
39Facial hemangioma (HP:0000329)2.46706036
40Abnormality of the astrocytes (HP:0100707)2.46226104
41Astrocytoma (HP:0009592)2.46226104
42Abnormality of methionine metabolism (HP:0010901)2.42873655
43Proximal placement of thumb (HP:0009623)2.41190500
44Long clavicles (HP:0000890)2.39665989
45Abnormality of glycolysis (HP:0004366)2.36698936
46Deviation of the thumb (HP:0009603)2.34828883
47Meckel diverticulum (HP:0002245)2.34768591
48Abnormality of the fingertips (HP:0001211)2.32628023
49Abnormality of the ileum (HP:0001549)2.32448842
50Broad distal phalanx of finger (HP:0009836)2.31619794
51Abnormality of chromosome stability (HP:0003220)2.29542184
52Ectopic kidney (HP:0000086)2.29243490
53High anterior hairline (HP:0009890)2.28921629
54Ragged-red muscle fibers (HP:0003200)2.27929669
55Aplastic anemia (HP:0001915)2.23252149
56Impulsivity (HP:0100710)2.22355569
57Absent thumb (HP:0009777)2.21961094
58IgM deficiency (HP:0002850)2.20501743
59Abnormal lung lobation (HP:0002101)2.19566802
60Nephroblastoma (Wilms tumor) (HP:0002667)2.19369075
61Broad palm (HP:0001169)2.18914195
62Volvulus (HP:0002580)2.18801761
63Missing ribs (HP:0000921)2.17907102
64High pitched voice (HP:0001620)2.17400118
65Duplicated collecting system (HP:0000081)2.16590650
66Hyperacusis (HP:0010780)2.15981950
67Increased serum pyruvate (HP:0003542)2.15295507
68Rhabdomyosarcoma (HP:0002859)2.14054678
69Abnormality of the preputium (HP:0100587)2.13527613
70Multiple enchondromatosis (HP:0005701)2.13073058
71Glioma (HP:0009733)2.12499160
72Trismus (HP:0000211)2.11280506
73Carpal bone hypoplasia (HP:0001498)2.10982730
74Thrombocytosis (HP:0001894)2.10579653
75Intestinal fistula (HP:0100819)2.09755901
76Abnormality of the labia minora (HP:0012880)2.08828239
77Increased serum lactate (HP:0002151)2.07795243
78Aplasia/Hypoplasia of the uvula (HP:0010293)2.07397501
79Insomnia (HP:0100785)2.07010116
80Squamous cell carcinoma (HP:0002860)2.06826960
81Small intestinal stenosis (HP:0012848)2.05949892
82Duodenal stenosis (HP:0100867)2.05949892
83Neoplasm of the oral cavity (HP:0100649)2.05582525
84Overriding aorta (HP:0002623)2.05438525
85Testicular atrophy (HP:0000029)2.05432419
86Gout (HP:0001997)2.05399081
87Embryonal renal neoplasm (HP:0011794)2.02171497
88Neoplasm of the pancreas (HP:0002894)2.01466223
89Amaurosis fugax (HP:0100576)1.98786379
90Heterotopia (HP:0002282)1.98481247
91Abnormal biliary tract physiology (HP:0012439)1.98218068
92Bile duct proliferation (HP:0001408)1.98218068
93Tongue fasciculations (HP:0001308)1.98141240
94Horseshoe kidney (HP:0000085)1.98023387
95Clubbing of toes (HP:0100760)1.97892239
96Absent radius (HP:0003974)1.95777091
97Preauricular skin tag (HP:0000384)1.95580532
98Abnormality of the calcaneus (HP:0008364)1.95119146
99Anal stenosis (HP:0002025)1.94987731
100Rough bone trabeculation (HP:0100670)1.94178905
101Skin tags (HP:0010609)1.93774572
102Renal duplication (HP:0000075)1.93631285
103Urethral obstruction (HP:0000796)1.93330413
104Cutaneous melanoma (HP:0012056)1.93146121
105Redundant skin (HP:0001582)1.93045448
106Aplasia/Hypoplasia of the sternum (HP:0006714)1.92890111
107Premature ovarian failure (HP:0008209)1.92311943
108Increased density of long bones (HP:0006392)1.91464881
109Rectovaginal fistula (HP:0000143)1.89732955
110Rectal fistula (HP:0100590)1.89732955
111Tracheoesophageal fistula (HP:0002575)1.89711960
112Abnormality of cochlea (HP:0000375)1.89134019
113Sloping forehead (HP:0000340)1.88897909
114Neoplasm of striated muscle (HP:0009728)1.88664578
115Bone marrow hypocellularity (HP:0005528)1.88424949
116Partial agenesis of the corpus callosum (HP:0001338)1.87480919
117Long eyelashes (HP:0000527)1.87189047
118Muscle fibrillation (HP:0010546)1.87048065
119Cutis marmorata (HP:0000965)1.86077785
120Cafe-au-lait spot (HP:0000957)1.85927321
121Slender long bone (HP:0003100)1.85776493
122Microretrognathia (HP:0000308)1.85183729
123Agnosia (HP:0010524)1.84492810
124Abnormal gallbladder physiology (HP:0012438)1.83954976
125Cholecystitis (HP:0001082)1.83954976
126Abnormality of the duodenum (HP:0002246)1.83745315
127Lymphoma (HP:0002665)1.83307134
128Abnormality of the carotid arteries (HP:0005344)1.82962995
129Atrophy/Degeneration involving motor neurons (HP:0007373)1.81926715
130Supernumerary spleens (HP:0009799)1.81424258
131Abnormality of the renal collecting system (HP:0004742)1.81336483
132Homocystinuria (HP:0002156)1.81097576
133Abnormality of homocysteine metabolism (HP:0010919)1.81097576
134Choanal atresia (HP:0000453)1.80957325
135Autoamputation (HP:0001218)1.80258602
136Combined immunodeficiency (HP:0005387)1.79648923
137Abnormality of the 4th metacarpal (HP:0010012)1.79382208
138Rib fusion (HP:0000902)1.79237451
139Abnormality of reticulocytes (HP:0004312)1.78432769
140Cortical dysplasia (HP:0002539)1.78245615
141Pallor (HP:0000980)1.77665802
142Truncus arteriosus (HP:0001660)1.77654277
143Absent forearm bone (HP:0003953)1.77244696
144Aplasia involving forearm bones (HP:0009822)1.77244696
145Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74260723
146Retinal dysplasia (HP:0007973)1.68719718
147Acute myeloid leukemia (HP:0004808)1.68069198
148Hypoplasia of the pons (HP:0012110)1.67709764
149Abnormality of sulfur amino acid metabolism (HP:0004339)1.67170456
150Limb hypertonia (HP:0002509)1.65853708
151Overlapping toe (HP:0001845)1.65428094
152Breech presentation (HP:0001623)1.62898390
153Opisthotonus (HP:0002179)1.62144536
154Cutaneous photosensitivity (HP:0000992)1.61575305

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.96177462
2WEE13.31435621
3CDK123.25638810
4BUB13.13651667
5TESK22.99123985
6NEK22.93768012
7EIF2AK12.70622447
8PBK2.66450563
9EEF2K2.49745742
10NEK12.37600985
11TSSK62.32656721
12ZAK2.24984431
13SRPK12.24723767
14SCYL22.13634689
15PASK2.07540382
16VRK22.06966444
17MAP3K101.99455907
18TTK1.91621739
19MAP4K11.86193274
20STK101.78852614
21CDK71.78508595
22ATR1.69943795
23PLK11.69126771
24ACVR1B1.57373096
25CDK41.53598815
26PAK41.51661040
27CCNB11.50980637
28BRSK21.47410475
29MKNK11.45556694
30TGFBR11.36090846
31AURKB1.32977509
32RPS6KB21.28774202
33BCKDK1.28149002
34MAP4K21.27433542
35PKN21.27424687
36CHEK21.21320990
37TESK11.19691860
38CHEK11.18331463
39RPS6KA41.18240100
40NME11.17011780
41BRD41.14249047
42MST41.13911191
43DYRK31.10842604
44CAMK1D1.09993052
45TRIB31.09736709
46MAP3K81.07046431
47SMG11.04666372
48PLK31.03459910
49BRSK11.03359956
50ALK1.02654836
51ICK0.99547925
52PLK40.98638854
53CDK20.98566830
54MKNK20.93757952
55MAP2K30.93529389
56LRRK20.91325464
57AURKA0.89616754
58STK160.89273800
59ZAP700.88651960
60TLK10.85414013
61MTOR0.85205507
62EIF2AK30.81333403
63ATM0.80502639
64ILK0.79432949
65TTN0.78750621
66CDK60.77487209
67NUAK10.76566622
68MAP3K110.76043342
69PIM10.75543517
70GRK60.74183713
71EIF2AK20.73620626
72PRKDC0.72179309
73TAOK20.72142045
74VRK10.71845521
75NME20.70347935
76CSNK1G30.69907999
77KDR0.69071336
78CAMK1G0.67281010
79PIM20.66278461
80CSNK1A1L0.66211797
81MAPKAPK50.65730172
82STK30.65304965
83MAPK110.64862775
84CDK10.63876051
85BTK0.63753590
86ERN10.63016667
87CSNK1G10.62729790
88JAK30.62559234
89FLT30.62033741
90CDK30.61094761
91RPS6KA50.59905818
92STK40.59774859
93CSF1R0.59569304
94CDK80.54433498
95TAOK10.53975169
96CHUK0.53552128
97PAK10.53515895
98MAPK100.51928518
99RPS6KL10.49876437
100RPS6KC10.49876437
101MAP3K30.49114207
102MAP3K70.48710692
103TGFBR20.48687709
104RPS6KA60.48291643
105CDK90.46920029
106CLK10.45710564
107CSNK2A20.45481901
108RAF10.45202869
109MAP3K130.43862289
110MELK0.42788997
111PDK20.42385692
112AKT20.41875920
113EPHA20.41766765
114PTK60.41368799
115CAMK40.39802845
116PAK20.39370413
117IRAK30.39365338
118FGFR10.39232082
119ERBB40.38623381
120CSNK2A10.38271249
121MATK0.37932595
122CSNK1E0.36583672
123PDGFRA0.36430342
124GSK3B0.36073888
125TXK0.35528425
126KIT0.35411343
127MAPK140.35161741
128MAP2K20.33816183
129CDK190.33474747
130PRKCI0.32962907
131DAPK10.32918822
132RPS6KA10.32711786
133BMX0.32158754
134MAP2K70.31747456
135CDK11A0.28396021
136CDK140.26548883
137MST1R0.25993003
138CDK150.22749689
139CSNK1A10.22349016
140MAPK90.22011102

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.90634793
2Mismatch repair_Homo sapiens_hsa034303.85288750
3Spliceosome_Homo sapiens_hsa030403.36313008
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.31440552
5RNA transport_Homo sapiens_hsa030133.18292385
6Base excision repair_Homo sapiens_hsa034103.15484465
7Cell cycle_Homo sapiens_hsa041102.89009103
8Homologous recombination_Homo sapiens_hsa034402.55357054
9Nucleotide excision repair_Homo sapiens_hsa034202.42653385
10One carbon pool by folate_Homo sapiens_hsa006702.41494789
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.35258737
12RNA polymerase_Homo sapiens_hsa030202.31459663
13mRNA surveillance pathway_Homo sapiens_hsa030152.22768840
14Ribosome_Homo sapiens_hsa030102.12534108
15Fanconi anemia pathway_Homo sapiens_hsa034601.98283903
16Pyrimidine metabolism_Homo sapiens_hsa002401.88058562
17Proteasome_Homo sapiens_hsa030501.77503718
18* RNA degradation_Homo sapiens_hsa030181.71163865
19Non-homologous end-joining_Homo sapiens_hsa034501.70695313
20p53 signaling pathway_Homo sapiens_hsa041151.63926017
21Basal transcription factors_Homo sapiens_hsa030221.44034338
22Epstein-Barr virus infection_Homo sapiens_hsa051691.37483305
23Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.28914104
24Viral carcinogenesis_Homo sapiens_hsa052031.25389009
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21830064
26HTLV-I infection_Homo sapiens_hsa051661.20383100
27Herpes simplex infection_Homo sapiens_hsa051681.19758100
28Antigen processing and presentation_Homo sapiens_hsa046121.14074781
29Primary immunodeficiency_Homo sapiens_hsa053401.13996426
30Colorectal cancer_Homo sapiens_hsa052101.10892019
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10212059
32Notch signaling pathway_Homo sapiens_hsa043301.09906556
33Oocyte meiosis_Homo sapiens_hsa041141.03919181
34Chronic myeloid leukemia_Homo sapiens_hsa052201.03298494
35Propanoate metabolism_Homo sapiens_hsa006401.02340018
36Fatty acid elongation_Homo sapiens_hsa000621.01522260
37Purine metabolism_Homo sapiens_hsa002300.97870387
38MicroRNAs in cancer_Homo sapiens_hsa052060.97174757
39Biosynthesis of amino acids_Homo sapiens_hsa012300.95832855
40Small cell lung cancer_Homo sapiens_hsa052220.95424203
41Pyruvate metabolism_Homo sapiens_hsa006200.93355659
42Cyanoamino acid metabolism_Homo sapiens_hsa004600.90048826
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89993348
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89422950
45Systemic lupus erythematosus_Homo sapiens_hsa053220.88345476
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83497481
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81075514
48Selenocompound metabolism_Homo sapiens_hsa004500.80160222
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79313005
50T cell receptor signaling pathway_Homo sapiens_hsa046600.79053777
51Pentose phosphate pathway_Homo sapiens_hsa000300.79044609
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.78554916
53Acute myeloid leukemia_Homo sapiens_hsa052210.77479148
54Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75756331
55B cell receptor signaling pathway_Homo sapiens_hsa046620.74752382
56Measles_Homo sapiens_hsa051620.73647301
57Legionellosis_Homo sapiens_hsa051340.73602803
58Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.72228973
59Viral myocarditis_Homo sapiens_hsa054160.71998893
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70012135
61Hepatitis B_Homo sapiens_hsa051610.69848680
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69179500
63Apoptosis_Homo sapiens_hsa042100.68580940
64Thyroid cancer_Homo sapiens_hsa052160.68103639
65Lysine degradation_Homo sapiens_hsa003100.67400896
66Hippo signaling pathway_Homo sapiens_hsa043900.66203934
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.65666784
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.65240130
69mTOR signaling pathway_Homo sapiens_hsa041500.64760463
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64659509
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64630164
72Shigellosis_Homo sapiens_hsa051310.64581234
73Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63005629
74Steroid biosynthesis_Homo sapiens_hsa001000.62472509
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62153267
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.60748674
77Central carbon metabolism in cancer_Homo sapiens_hsa052300.60401204
78TGF-beta signaling pathway_Homo sapiens_hsa043500.58950036
79Pancreatic cancer_Homo sapiens_hsa052120.58182036
80Fatty acid metabolism_Homo sapiens_hsa012120.57975835
81Basal cell carcinoma_Homo sapiens_hsa052170.55369367
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.55222500
83N-Glycan biosynthesis_Homo sapiens_hsa005100.54674431
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.54282690
85Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.52916437
86Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.52632345
87Adherens junction_Homo sapiens_hsa045200.50769678
88Influenza A_Homo sapiens_hsa051640.49981392
89Galactose metabolism_Homo sapiens_hsa000520.49778569
90HIF-1 signaling pathway_Homo sapiens_hsa040660.49156268
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48828899
92Non-small cell lung cancer_Homo sapiens_hsa052230.46848490
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45137067
94Metabolic pathways_Homo sapiens_hsa011000.44510238
95Peroxisome_Homo sapiens_hsa041460.44419749
96Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44045919
97Carbon metabolism_Homo sapiens_hsa012000.43809717
98Huntingtons disease_Homo sapiens_hsa050160.43753850
99Pathways in cancer_Homo sapiens_hsa052000.43563650
100Protein export_Homo sapiens_hsa030600.43211487
101Endometrial cancer_Homo sapiens_hsa052130.39090439
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.38536985
103Butanoate metabolism_Homo sapiens_hsa006500.38234259
104Proteoglycans in cancer_Homo sapiens_hsa052050.37956064
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.36866401
106Leishmaniasis_Homo sapiens_hsa051400.35970493
107Sulfur relay system_Homo sapiens_hsa041220.34282986
108Parkinsons disease_Homo sapiens_hsa050120.33836617
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.33417974
110Hedgehog signaling pathway_Homo sapiens_hsa043400.33007515
111Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.31362925
112Alcoholism_Homo sapiens_hsa050340.31030171
113Leukocyte transendothelial migration_Homo sapiens_hsa046700.30777130
114Glutathione metabolism_Homo sapiens_hsa004800.30689090
115Toxoplasmosis_Homo sapiens_hsa051450.29383567
116VEGF signaling pathway_Homo sapiens_hsa043700.29325952
117Bladder cancer_Homo sapiens_hsa052190.29217218
118Hematopoietic cell lineage_Homo sapiens_hsa046400.28967606
119Prostate cancer_Homo sapiens_hsa052150.28368071
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.27972296
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27235495
122Fructose and mannose metabolism_Homo sapiens_hsa000510.26860866
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26673348
124Prolactin signaling pathway_Homo sapiens_hsa049170.25977143
125AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.25355120
126Renal cell carcinoma_Homo sapiens_hsa052110.23087763
127Wnt signaling pathway_Homo sapiens_hsa043100.23019092
128Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22981847
129Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.22284119
130Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.19025375
131NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18450750
132Drug metabolism - other enzymes_Homo sapiens_hsa009830.15723935
133Folate biosynthesis_Homo sapiens_hsa007900.15506689
134Oxidative phosphorylation_Homo sapiens_hsa001900.12004013
135Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.06569775
136Arginine and proline metabolism_Homo sapiens_hsa003300.06107030
137Sphingolipid metabolism_Homo sapiens_hsa006000.04675062

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