FABP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.29948668
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.29948668
3L-phenylalanine metabolic process (GO:0006558)7.00890743
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.00890743
5triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.78760690
6aromatic amino acid family catabolic process (GO:0009074)6.60544167
7regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)6.12152997
8tryptophan catabolic process (GO:0006569)5.99534706
9indole-containing compound catabolic process (GO:0042436)5.99534706
10indolalkylamine catabolic process (GO:0046218)5.99534706
11high-density lipoprotein particle remodeling (GO:0034375)5.90238115
12kynurenine metabolic process (GO:0070189)5.90008535
13alpha-linolenic acid metabolic process (GO:0036109)5.88231738
14bile acid biosynthetic process (GO:0006699)5.85263362
15epoxygenase P450 pathway (GO:0019373)5.82238786
16tryptophan metabolic process (GO:0006568)5.64227244
17glyoxylate metabolic process (GO:0046487)5.57769620
18urea metabolic process (GO:0019627)5.55004856
19urea cycle (GO:0000050)5.55004856
20negative regulation of fibrinolysis (GO:0051918)5.50961577
21regulation of cholesterol esterification (GO:0010872)5.48120723
22* intestinal absorption (GO:0050892)5.47493399
23regulation of fibrinolysis (GO:0051917)5.27992693
24protein carboxylation (GO:0018214)5.25170171
25peptidyl-glutamic acid carboxylation (GO:0017187)5.25170171
26regulation of triglyceride catabolic process (GO:0010896)5.13767736
27phospholipid efflux (GO:0033700)5.13526964
28cysteine metabolic process (GO:0006534)5.11757472
29reverse cholesterol transport (GO:0043691)5.11724127
30sulfur amino acid catabolic process (GO:0000098)5.10429277
31nitrogen cycle metabolic process (GO:0071941)5.09878498
32plasma lipoprotein particle remodeling (GO:0034369)5.07183387
33protein-lipid complex remodeling (GO:0034368)5.07183387
34macromolecular complex remodeling (GO:0034367)5.07183387
35bile acid metabolic process (GO:0008206)5.05370142
36regulation of protein activation cascade (GO:2000257)5.05028424
37complement activation, alternative pathway (GO:0006957)5.03001583
38fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.00868888
39angiotensin maturation (GO:0002003)4.99997943
40negative regulation of cholesterol transport (GO:0032375)4.94564681
41negative regulation of sterol transport (GO:0032372)4.94564681
42serine family amino acid catabolic process (GO:0009071)4.90930749
43aromatic amino acid family metabolic process (GO:0009072)4.80687685
44regulation of complement activation (GO:0030449)4.68918671
45acylglycerol homeostasis (GO:0055090)4.66833663
46triglyceride homeostasis (GO:0070328)4.66833663
47fat-soluble vitamin biosynthetic process (GO:0042362)4.66514417
48tyrosine metabolic process (GO:0006570)4.60508977
49plasma lipoprotein particle clearance (GO:0034381)4.59147935
50cholesterol efflux (GO:0033344)4.56518082
51amino-acid betaine metabolic process (GO:0006577)4.56289900
52diacylglycerol metabolic process (GO:0046339)4.52409507
53homocysteine metabolic process (GO:0050667)4.50316148
54alpha-amino acid catabolic process (GO:1901606)4.47227190
55lysine metabolic process (GO:0006553)4.46913985
56lysine catabolic process (GO:0006554)4.46913985
57cellular ketone body metabolic process (GO:0046950)4.45307833
58exogenous drug catabolic process (GO:0042738)4.44032591
59plasma lipoprotein particle assembly (GO:0034377)4.41552986
60bile acid and bile salt transport (GO:0015721)4.41417403
61ethanol metabolic process (GO:0006067)4.37216017
62cellular glucuronidation (GO:0052695)4.28622549
63indolalkylamine metabolic process (GO:0006586)4.24556680
64coenzyme catabolic process (GO:0009109)4.24178536
65drug metabolic process (GO:0017144)4.23436480
66glycine metabolic process (GO:0006544)4.22297920
67drug catabolic process (GO:0042737)4.19699648
68renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)4.17825597
69low-density lipoprotein particle remodeling (GO:0034374)4.16869589
70amine catabolic process (GO:0009310)4.16028763
71cellular biogenic amine catabolic process (GO:0042402)4.16028763
72very-low-density lipoprotein particle assembly (GO:0034379)4.15735578
73benzene-containing compound metabolic process (GO:0042537)4.13512764
74positive regulation of lipoprotein lipase activity (GO:0051006)4.13187386
75positive regulation of triglyceride lipase activity (GO:0061365)4.13187386
76cellular amino acid catabolic process (GO:0009063)4.11518682
77imidazole-containing compound metabolic process (GO:0052803)4.11113782
78glutamate metabolic process (GO:0006536)4.08622940
79ethanol oxidation (GO:0006069)4.05179842
80serine family amino acid metabolic process (GO:0009069)4.00794742
81lipoprotein transport (GO:0042953)3.97685872
82protein-lipid complex assembly (GO:0065005)3.96580091
83NADH metabolic process (GO:0006734)3.94918398
84dicarboxylic acid biosynthetic process (GO:0043650)3.93879855
85regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.93534925
86endocrine process (GO:0050886)3.93534925
87regulation of systemic arterial blood pressure by hormone (GO:0001990)3.93534925
88negative regulation of lipase activity (GO:0060192)3.91688924
89arginine metabolic process (GO:0006525)3.91478760
90cellular modified amino acid catabolic process (GO:0042219)3.89792118
91fibrinolysis (GO:0042730)3.88778324
92plasma lipoprotein particle organization (GO:0071827)3.87654690
93cholesterol homeostasis (GO:0042632)3.87592593
94ketone body metabolic process (GO:1902224)3.85307954
95serine family amino acid biosynthetic process (GO:0009070)3.85229855
96regulation of guanylate cyclase activity (GO:0031282)3.83223187
97phospholipid homeostasis (GO:0055091)3.82084348
98aldehyde catabolic process (GO:0046185)3.82074882
99sterol homeostasis (GO:0055092)3.81177025
100uronic acid metabolic process (GO:0006063)3.80232910
101glucuronate metabolic process (GO:0019585)3.80232910
102intestinal cholesterol absorption (GO:0030299)3.78910752
103blood coagulation, intrinsic pathway (GO:0007597)3.73499733
104cofactor catabolic process (GO:0051187)3.72137208
105sulfate transmembrane transport (GO:1902358)3.71970096
106flavonoid metabolic process (GO:0009812)3.71266427
107protein activation cascade (GO:0072376)3.71146165
108renal system process involved in regulation of blood volume (GO:0001977)3.71108139
109short-chain fatty acid metabolic process (GO:0046459)3.71091036
110regulation of bile acid biosynthetic process (GO:0070857)3.70521782
111negative regulation of hemostasis (GO:1900047)3.69792661
112negative regulation of blood coagulation (GO:0030195)3.69792661
113drug transmembrane transport (GO:0006855)3.68350921
114* positive regulation of lipid catabolic process (GO:0050996)3.67985595
115lipoprotein metabolic process (GO:0042157)3.67247494
116organic acid catabolic process (GO:0016054)3.66413676
117carboxylic acid catabolic process (GO:0046395)3.66413676
118heme transport (GO:0015886)3.66113875
119protein-lipid complex subunit organization (GO:0071825)3.65018706
120regulation of cholesterol homeostasis (GO:2000188)3.64068940
121acetyl-CoA metabolic process (GO:0006084)3.62547584
122maintenance of gastrointestinal epithelium (GO:0030277)3.60213247
123complement activation, classical pathway (GO:0006958)3.59227392
124regulation of plasminogen activation (GO:0010755)3.54888116
125regulation of apoptotic cell clearance (GO:2000425)3.54399691
126hormone catabolic process (GO:0042447)3.45940435
127complement activation (GO:0006956)3.45903857
128proline metabolic process (GO:0006560)3.44412033
129acute-phase response (GO:0006953)3.44024082
130drug transport (GO:0015893)3.43977177
131negative regulation of coagulation (GO:0050819)3.43150683
132positive regulation of fatty acid biosynthetic process (GO:0045723)3.33225703
133fructose metabolic process (GO:0006000)3.30927729
134regulation of systemic arterial blood pressure (GO:0003073)3.30382861
135glutamine family amino acid biosynthetic process (GO:0009084)3.27132481
136phenylpropanoid metabolic process (GO:0009698)3.20646820
137negative regulation of wound healing (GO:0061045)3.20574803
138regulation of cholesterol metabolic process (GO:0090181)3.18180908
139regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.13310705
140negative regulation of protein activation cascade (GO:2000258)3.11282159
141transcytosis (GO:0045056)3.11195142
142vitamin transmembrane transport (GO:0035461)3.07205140
143omega-hydroxylase P450 pathway (GO:0097267)3.06484987

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.33837183
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.19358921
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.99562433
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.49879292
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.08549208
6* FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.07337327
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.98967915
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.04101271
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.96476300
10CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.21878782
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.30858893
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.10571032
13TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.04737013
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00208503
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8425158
16FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.80126326
17CDX2_19796622_ChIP-Seq_MESCs_Mouse1.74034411
18TCF4_18268006_ChIP-ChIP_LS174T_Human1.70846690
19* FOXA2_19822575_ChIP-Seq_HepG2_Human1.60868109
20CLOCK_20551151_ChIP-Seq_293T_Human1.58460677
21HTT_18923047_ChIP-ChIP_STHdh_Human1.55304054
22TRIM28_21343339_ChIP-Seq_HEK293_Human1.50805100
23GATA1_22025678_ChIP-Seq_K562_Human1.47341057
24* HNF4A_19822575_ChIP-Seq_HepG2_Human1.43078168
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.42743968
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.26871711
27STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.24309638
28RACK7_27058665_Chip-Seq_MCF-7_Human1.20641752
29AR_21909140_ChIP-Seq_LNCAP_Human1.18175870
30RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17107478
31TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.11203844
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10170079
33KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09911613
34STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.07189617
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05614533
36SOX2_27498859_Chip-Seq_STOMACH_Mouse1.04454022
37ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03599727
38ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03461378
39ESR1_15608294_ChIP-ChIP_MCF-7_Human1.02707331
40SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02230659
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99902150
42CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98941323
43P63_26484246_Chip-Seq_KERATINOCYTES_Human0.97021802
44JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.96640428
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94771437
46GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.93769227
47ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93594357
48RUNX1_27514584_Chip-Seq_MCF-7_Human0.91727411
49GATA4_25053715_ChIP-Seq_YYC3_Human0.91602152
50IRF8_22096565_ChIP-ChIP_GC-B_Human0.91388673
51PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.88151862
52TET1_21451524_ChIP-Seq_MESCs_Mouse0.87017775
53DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85322785
54RARG_19884340_ChIP-ChIP_MEFs_Mouse0.83135945
55AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82481971
56KAP1_22055183_ChIP-Seq_ESCs_Mouse0.81788985
57KLF5_25053715_ChIP-Seq_YYC3_Human0.81352964
58HIF1A_21447827_ChIP-Seq_MCF-7_Human0.81168611
59POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80009067
60ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.79729715
61ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.79512842
62BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78822265
63SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.76807992
64SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.76709384
65RARA_24833708_ChIP-Seq_LIVER_Mouse0.75670596
66SA1_27219007_Chip-Seq_Bcells_Human0.75477158
67SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.75093085
68Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.73887535
69SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.73876527
70ZNF263_19887448_ChIP-Seq_K562_Human0.73790348
71BCOR_27268052_Chip-Seq_Bcells_Human0.73484105
72GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70509363
73DROSHA_22980978_ChIP-Seq_HELA_Human0.70150356
74SALL4_18804426_ChIP-ChIP_XEN_Mouse0.70054927
75BCL6_27268052_Chip-Seq_Bcells_Human0.69997298
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.69170614
77CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69164688
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.68873884
79AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.68836286
80TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.68712290
81ESR2_21235772_ChIP-Seq_MCF-7_Human0.67900081
82ETS1_21867929_ChIP-Seq_TH2_Mouse0.66476292
83NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.65770300
84CTCF_27219007_Chip-Seq_Bcells_Human0.65632412
85RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.65105015
86NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.65006750
87CDX2_20551321_ChIP-Seq_CACO-2_Human0.64775894
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.64211543
89NRF2_20460467_ChIP-Seq_MEFs_Mouse0.64075644
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.64075644
91RAD21_21589869_ChIP-Seq_MESCs_Mouse0.62471977
92BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.62422604
93RARB_24833708_ChIP-Seq_LIVER_Mouse0.62073587
94CEBPB_22108803_ChIP-Seq_LS180_Human0.59505919
95PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.55859268
96EGR1_19032775_ChIP-ChIP_M12_Human0.54699490
97LXR_22292898_ChIP-Seq_THP-1_Human0.53384463
98E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.52981755
99FOXA1_25552417_ChIP-Seq_VCAP_Human0.52962068
100AR_20517297_ChIP-Seq_VCAP_Human0.52674234
101FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.52208945
102MYC_19915707_ChIP-ChIP_AK7_Human0.52076323
103ESET_19884257_ChIP-Seq_ESCs_Mouse0.50652684
104PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.50010263
105FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.49996380
106STAT3_1855785_ChIP-Seq_MESCs_Mouse0.49970002
107STAT1_17558387_ChIP-Seq_HELA_Human0.49367799
108CBP_21632823_ChIP-Seq_H3396_Human0.48762903
109PPAR_26484153_Chip-Seq_NCI-H1993_Human0.47634866
110GATA6_25053715_ChIP-Seq_YYC3_Human0.47624664
111P53_21459846_ChIP-Seq_SAOS-2_Human0.47038031
112PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.46710116
113PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.45171615
114BCAT_22108803_ChIP-Seq_LS180_Human0.44418222
115FOXO3_23340844_ChIP-Seq_DLD1_Human0.43931163
116FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.43753767
117ESR1_21235772_ChIP-Seq_MCF-7_Human0.43727501
118GATA2_19941826_ChIP-Seq_K562_Human0.43605967
119ESR1_20079471_ChIP-ChIP_T-47D_Human0.42995707
120TAF15_26573619_Chip-Seq_HEK293_Human0.41983493
121GATA1_19941826_ChIP-Seq_K562_Human0.41688015
122TAF2_19829295_ChIP-Seq_ESCs_Human0.40659607
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.40478516
124SOX2_20726797_ChIP-Seq_SW620_Human0.40444750
125* GATA1_19941827_ChIP-Seq_MEL_Mouse0.40437166
126CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39117783
127LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.36380674
128NCOR_22424771_ChIP-Seq_293T_Human0.36081007
129CDX2_22108803_ChIP-Seq_LS180_Human0.35886195
130SPI1_26923725_Chip-Seq_HPCs_Mouse0.35626408
131ERG_21242973_ChIP-ChIP_JURKAT_Human0.35185505
132SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35166311
133MYC_27129775_Chip-Seq_CORNEA_Mouse0.35080524
134CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.35077228
135FOXH1_21741376_ChIP-Seq_EPCs_Human0.34803468
136GATA3_24758297_ChIP-Seq_MCF-7_Human0.34225204
137EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.33859967

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0002139_abnormal_hepatobiliary_system7.73822615
2MP0005360_urolithiasis7.72961015
3MP0005085_abnormal_gallbladder_physiolo6.51966942
4MP0005365_abnormal_bile_salt6.35174201
5MP0008875_abnormal_xenobiotic_pharmacok5.21732276
6MP0003806_abnormal_nucleotide_metabolis4.19889720
7MP0003252_abnormal_bile_duct4.03665887
8MP0010329_abnormal_lipoprotein_level3.70885733
9MP0009840_abnormal_foam_cell3.61626655
10MP0005083_abnormal_biliary_tract3.06704649
11MP0001666_abnormal_nutrient_absorption2.85909660
12MP0005332_abnormal_amino_acid2.71929524
13MP0003195_calcinosis2.68197437
14MP0003183_abnormal_peptide_metabolism2.47559403
15MP0003191_abnormal_cellular_cholesterol2.32473543
16MP0004019_abnormal_vitamin_homeostasis2.17063814
17* MP0000609_abnormal_liver_physiology2.15587258
18* MP0002118_abnormal_lipid_homeostasis2.12216426
19MP0003866_abnormal_defecation2.01656514
20MP0004043_abnormal_pH_regulation1.95262215
21MP0002138_abnormal_hepatobiliary_system1.94830518
22MP0003868_abnormal_feces_composition1.88434260
23MP0005409_darkened_coat_color1.87948654
24MP0005319_abnormal_enzyme/_coenzyme1.81847006
25MP0010155_abnormal_intestine_physiology1.80141787
26MP0009697_abnormal_copulation1.72587496
27MP0001764_abnormal_homeostasis1.67436485
28MP0000566_synostosis1.57254420
29MP0005584_abnormal_enzyme/coenzyme_acti1.54485607
30MP0004147_increased_porphyrin_level1.54130086
31MP0005451_abnormal_body_composition1.54070280
32MP0009379_abnormal_foot_pigmentation1.53066397
33MP0000477_abnormal_intestine_morphology1.44092775
34MP0001765_abnormal_ion_homeostasis1.39523192
35MP0001664_abnormal_digestion1.39338824
36MP0003122_maternal_imprinting1.37458783
37MP0010352_gastrointestinal_tract_polyps1.37074078
38MP0003011_delayed_dark_adaptation1.35119416
39MP0005058_abnormal_lysosome_morphology1.30692883
40MP0009643_abnormal_urine_homeostasis1.24069493
41MP0001663_abnormal_digestive_system1.21388957
42MP0003656_abnormal_erythrocyte_physiolo1.20418053
43MP0003879_abnormal_hair_cell1.20197388
44MP0003186_abnormal_redox_activity1.19338471
45MP0000598_abnormal_liver_morphology1.15508491
46MP0005647_abnormal_sex_gland1.11189008
47MP0003705_abnormal_hypodermis_morpholog1.11050628
48MP0000604_amyloidosis1.10833363
49MP0002089_abnormal_postnatal_growth/wei1.07450292
50MP0000678_abnormal_parathyroid_gland1.07009480
51MP0009764_decreased_sensitivity_to1.06012438
52MP0000490_abnormal_crypts_of1.05764139
53MP0002254_reproductive_system_inflammat1.01473860
54MP0009763_increased_sensitivity_to0.99618937
55MP0005381_digestive/alimentary_phenotyp0.99348050
56MP0005636_abnormal_mineral_homeostasis0.94279207
57MP0010368_abnormal_lymphatic_system0.89666933
58MP0005084_abnormal_gallbladder_morpholo0.89176745
59MP0008469_abnormal_protein_level0.88850588
60* MP0009642_abnormal_blood_homeostasis0.87310287
61MP0001873_stomach_inflammation0.84526276
62MP0005408_hypopigmentation0.81533080
63MP0006036_abnormal_mitochondrial_physio0.81120604
64MP0005376_homeostasis/metabolism_phenot0.80532053
65MP0002876_abnormal_thyroid_physiology0.79279338
66MP0009765_abnormal_xenobiotic_induced0.78623297
67* MP0002078_abnormal_glucose_homeostasis0.75651508
68MP0003172_abnormal_lysosome_physiology0.74970473
69MP0005257_abnormal_intraocular_pressure0.73916875
70MP0003123_paternal_imprinting0.73272827
71MP0002166_altered_tumor_susceptibility0.72354894
72MP0002971_abnormal_brown_adipose0.71899166
73MP0005334_abnormal_fat_pad0.71326293
74MP0009053_abnormal_anal_canal0.70268063
75MP0004858_abnormal_nervous_system0.69991269
76MP0002098_abnormal_vibrissa_morphology0.68484022
77MP0005670_abnormal_white_adipose0.68361015
78MP0005220_abnormal_exocrine_pancreas0.67003412
79MP0003690_abnormal_glial_cell0.66814292
80MP0005266_abnormal_metabolism0.66309563
81MP0003329_amyloid_beta_deposits0.65179459
82MP0005535_abnormal_body_temperature0.65013912
83MP0004130_abnormal_muscle_cell0.64848153
84MP0005448_abnormal_energy_balance0.62488228
85MP0003315_abnormal_perineum_morphology0.60374612
86MP0009785_altered_susceptibility_to0.60370102
87MP0002822_catalepsy0.59378398
88MP0000639_abnormal_adrenal_gland0.59319440
89MP0001661_extended_life_span0.58694993
90MP0001756_abnormal_urination0.58555572
91MP0009780_abnormal_chondrocyte_physiolo0.58546652
92MP0003567_abnormal_fetal_cardiomyocyte0.58173768
93MP0006035_abnormal_mitochondrial_morpho0.57549909
94MP0000462_abnormal_digestive_system0.57262727
95MP0005464_abnormal_platelet_physiology0.53813527
96MP0002896_abnormal_bone_mineralization0.52693275
97MP0009333_abnormal_splenocyte_physiolog0.52209330
98MP0000538_abnormal_urinary_bladder0.50095838
99MP0003718_maternal_effect0.48537532
100MP0003638_abnormal_response/metabolism_0.47549601
101MP0005395_other_phenotype0.46899370
102MP0005023_abnormal_wound_healing0.46589824
103MP0002136_abnormal_kidney_physiology0.46583527
104MP0003303_peritoneal_inflammation0.46396241
105MP0003300_gastrointestinal_ulcer0.46312948
106MP0008874_decreased_physiological_sensi0.45609595
107MP0008873_increased_physiological_sensi0.44912874
108MP0002928_abnormal_bile_duct0.43594918
109MP0005025_abnormal_response_to0.42456117
110MP0001915_intracranial_hemorrhage0.42068470
111MP0006054_spinal_hemorrhage0.41414715
112MP0008872_abnormal_physiological_respon0.40348169
113MP0004782_abnormal_surfactant_physiolog0.40321841
114MP0003075_altered_response_to0.39508685
115* MP0003953_abnormal_hormone_level0.39429634
116MP0005248_abnormal_Harderian_gland0.39177742
117MP0003724_increased_susceptibility_to0.38937291
118MP0005166_decreased_susceptibility_to0.38260380
119MP0002796_impaired_skin_barrier0.37908611
120MP0003436_decreased_susceptibility_to0.37640336
121MP0002837_dystrophic_cardiac_calcinosis0.35799323
122MP0009115_abnormal_fat_cell0.35562038
123MP0005666_abnormal_adipose_tissue0.35418303
124MP0000579_abnormal_nail_morphology0.33674863
125MP0004381_abnormal_hair_follicle0.33596632
126MP0000249_abnormal_blood_vessel0.33003006
127MP0006082_CNS_inflammation0.32998866
128MP0000230_abnormal_systemic_arterial0.32383445
129MP0001881_abnormal_mammary_gland0.32371426
130MP0009672_abnormal_birth_weight0.32279485
131MP0001243_abnormal_dermal_layer0.31551691
132MP0004883_abnormal_blood_vessel0.31426429
133MP0002970_abnormal_white_adipose0.29260239
134MP0004264_abnormal_extraembryonic_tissu0.29176899
135MP0001853_heart_inflammation0.29128967
136MP0001845_abnormal_inflammatory_respons0.28034796
137MP0002168_other_aberrant_phenotype0.27730108
138MP0009384_cardiac_valve_regurgitation0.27360458
139MP0010234_abnormal_vibrissa_follicle0.26604410
140MP0005164_abnormal_response_to0.23994170
141MP0002132_abnormal_respiratory_system0.23948409

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.31228721
2Intrahepatic cholestasis (HP:0001406)7.29178792
3Abnormality of aromatic amino acid family metabolism (HP:0004338)7.19077230
4Hypobetalipoproteinemia (HP:0003563)6.83180140
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.63911925
6Prolonged partial thromboplastin time (HP:0003645)6.49049717
7Xanthomatosis (HP:0000991)6.35148516
8Hyperlipoproteinemia (HP:0010980)5.50810487
9Complement deficiency (HP:0004431)5.04063045
10Hypolipoproteinemia (HP:0010981)5.00595741
11Joint hemorrhage (HP:0005261)4.70681533
12Hyperammonemia (HP:0001987)4.58196036
13Epidermoid cyst (HP:0200040)4.55837125
14Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.54430662
15Abnormality of the common coagulation pathway (HP:0010990)4.37624118
16Hyperactive renin-angiotensin system (HP:0000841)4.33590496
17Hyperglycinemia (HP:0002154)4.31169704
18Flat acetabular roof (HP:0003180)4.27205758
19Fat malabsorption (HP:0002630)4.26651259
20Ketosis (HP:0001946)4.22642456
21Hypoalphalipoproteinemia (HP:0003233)4.22248954
22Abnormality of glutamine family amino acid metabolism (HP:0010902)4.16563082
23Abnormality of sulfur amino acid metabolism (HP:0004339)4.14689024
24Abnormality of methionine metabolism (HP:0010901)4.10981071
25Abnormality of aspartate family amino acid metabolism (HP:0010899)4.06008370
26Hypoglycemic coma (HP:0001325)4.01622361
27Hyperglycinuria (HP:0003108)3.91870158
28Conjugated hyperbilirubinemia (HP:0002908)3.88738270
29Abnormality of serine family amino acid metabolism (HP:0010894)3.87567808
30Abnormality of glycine metabolism (HP:0010895)3.87567808
31Abnormality of pyrimidine metabolism (HP:0004353)3.79000272
32Hypercholesterolemia (HP:0003124)3.77432994
33Metabolic alkalosis (HP:0200114)3.75144468
34Abnormality of the intrinsic pathway (HP:0010989)3.70582860
35Abnormality of complement system (HP:0005339)3.67329516
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.42911274
37Hyperbilirubinemia (HP:0002904)3.41776129
38Abnormal tarsal ossification (HP:0008369)3.41630744
39Abnormality of fatty-acid metabolism (HP:0004359)3.37671026
40Alkalosis (HP:0001948)3.21287704
41Decreased circulating renin level (HP:0003351)3.17109781
42Ileus (HP:0002595)3.11916726
43Abnormality of renin-angiotensin system (HP:0000847)3.11658004
44Steatorrhea (HP:0002570)3.11327149
45Abnormality of carpal bone ossification (HP:0006257)3.10730538
46Ketoacidosis (HP:0001993)3.08990357
47Abnormality of nucleobase metabolism (HP:0010932)3.06681912
48Delayed CNS myelination (HP:0002188)3.03670639
49Abnormality of serum amino acid levels (HP:0003112)2.95748847
50Widely patent fontanelles and sutures (HP:0004492)2.93328111
51Spontaneous abortion (HP:0005268)2.93097312
52Nephritis (HP:0000123)2.91854696
53Acanthocytosis (HP:0001927)2.89442410
54Hypochromic microcytic anemia (HP:0004840)2.88063639
55Hepatocellular carcinoma (HP:0001402)2.86961995
56Myocardial infarction (HP:0001658)2.84744383
57Metabolic acidosis (HP:0001942)2.81614278
58Skin nodule (HP:0200036)2.78777500
59Abnormality of purine metabolism (HP:0004352)2.70522731
60Hypoglycemic seizures (HP:0002173)2.63863096
61Abnormality of dicarboxylic acid metabolism (HP:0010995)2.58677706
62Dicarboxylic aciduria (HP:0003215)2.58677706
63Vascular calcification (HP:0004934)2.58657006
64Systemic lupus erythematosus (HP:0002725)2.58424167
65Lethargy (HP:0001254)2.58393422
66Abdominal distention (HP:0003270)2.57475239
67Abnormal gallbladder morphology (HP:0012437)2.50325469
68Malnutrition (HP:0004395)2.48967207
69Right ventricular cardiomyopathy (HP:0011663)2.47848454
70Cholecystitis (HP:0001082)2.45040143
71Abnormal gallbladder physiology (HP:0012438)2.45040143
72Cholelithiasis (HP:0001081)2.43961347
73Spastic diplegia (HP:0001264)2.43435277
74Abnormality of chloride homeostasis (HP:0011422)2.41979892
75Cerebral edema (HP:0002181)2.36738768
76Glomerulonephritis (HP:0000099)2.36209661
77Amyloidosis (HP:0011034)2.35754241
78Mitral stenosis (HP:0001718)2.34291921
79Irritability (HP:0000737)2.33745795
80Abnormal hand bone ossification (HP:0010660)2.33523434
81Pigmentary retinal degeneration (HP:0001146)2.33348518
82Abnormal ossification of hand bones (HP:0005921)2.30610737
83Proximal tubulopathy (HP:0000114)2.30241175
84Cardiovascular calcification (HP:0011915)2.29118738
85Neonatal short-limb short stature (HP:0008921)2.28761928
86Late onset (HP:0003584)2.27446749
87Purpura (HP:0000979)2.26233027
88Neonatal onset (HP:0003623)2.25470521
89Gout (HP:0001997)2.24980360
90Abnormality of the vitamin B12 metabolism (HP:0004341)2.23131273
91Potter facies (HP:0002009)2.21883525
92Facial shape deformation (HP:0011334)2.21883525
93Poikilocytosis (HP:0004447)2.21214206
94Gingival bleeding (HP:0000225)2.18651903
95Wide cranial sutures (HP:0010537)2.18276891
96Recurrent gram-negative bacterial infections (HP:0005420)2.18200829
97Brushfield spots (HP:0001088)2.17332686
98Hyperinsulinemic hypoglycemia (HP:0000825)2.16279865
99Sensorimotor neuropathy (HP:0007141)2.15898733
100Hypotension (HP:0002615)2.15682018
101Esophageal varix (HP:0002040)2.15524661
102Pancreatitis (HP:0001733)2.14742859
103Abnormal foot bone ossification (HP:0010675)2.14696748
104Menorrhagia (HP:0000132)2.11674976
105Chronic diarrhea (HP:0002028)2.07289542
106Hyperaldosteronism (HP:0000859)2.07149569
107Abnormality of vitamin B metabolism (HP:0004340)2.06541455
108Vomiting (HP:0002013)2.05994596
109Generalized aminoaciduria (HP:0002909)2.03625433
110Abnormality of iron homeostasis (HP:0011031)2.02709577
111Abnormality of the gallbladder (HP:0005264)2.02051475
112Opisthotonus (HP:0002179)2.02017691
113Thrombophlebitis (HP:0004418)2.00541851
114Abnormality of transition element cation homeostasis (HP:0011030)2.00356172
115Enlarged kidneys (HP:0000105)2.00120416
116Rickets (HP:0002748)1.98607574
117Focal segmental glomerulosclerosis (HP:0000097)1.98225748
118Hypophosphatemia (HP:0002148)1.96527697
119Hemorrhage of the eye (HP:0011885)1.96254961
120Thin bony cortex (HP:0002753)1.95391129
121Abnormality of proline metabolism (HP:0010907)1.93419649
122Hydroxyprolinuria (HP:0003080)1.93419649
123Hyponatremia (HP:0002902)1.93074007
124Confusion (HP:0001289)1.92434466
125Renal cortical cysts (HP:0000803)1.89787926
126Abnormal cartilage morphology (HP:0002763)1.88799673
127Increased serum pyruvate (HP:0003542)1.84565688
128Reticulocytosis (HP:0001923)1.83295171
129Hypokalemia (HP:0002900)1.82487969
130Glomerulosclerosis (HP:0000096)1.82375735
131Hyperphosphaturia (HP:0003109)1.82226506
132Abnormality of vitamin metabolism (HP:0100508)1.81622954
133Abnormality of urine glucose concentration (HP:0011016)1.81255946
134Glycosuria (HP:0003076)1.81255946
135Hyperglycemia (HP:0003074)1.80979854
136Cupped ribs (HP:0000887)1.80328338
137Hypophosphatemic rickets (HP:0004912)1.79898289
138Nephrolithiasis (HP:0000787)1.79337016
139Elevated hepatic transaminases (HP:0002910)1.79302318
140Abnormal enzyme/coenzyme activity (HP:0012379)1.78001541
141Osteomalacia (HP:0002749)1.77684802
142Visceral angiomatosis (HP:0100761)1.76235637

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.98721996
2ACVR1B4.85335017
3SIK14.58310030
4FGFR44.36480535
5ERN14.28001373
6EPHA24.16006798
7TAOK33.27959596
8INSRR2.91749443
9ERBB42.74394258
10LMTK22.53177475
11MST1R2.39775901
12PKN22.33984959
13WNK42.32686391
14MAP2K42.25681661
15PIK3CG2.04334206
16FLT31.96222135
17FRK1.88761240
18MAPK111.84117234
19DAPK21.83723699
20STK391.82777352
21TRIB31.68650988
22TYK21.66716020
23LATS11.62226996
24PTK61.58016268
25DDR21.52088139
26ABL21.44169808
27MAP3K21.42658207
28GRK61.32085615
29FGFR21.30462082
30NEK91.30279742
31KDR1.30276424
32PDGFRA1.26817135
33MAP3K71.21975674
34JAK21.19025316
35PRKAA21.18926651
36MAP3K101.17091111
37EPHB21.14797605
38TBK11.11810194
39TESK21.07936876
40STK241.06142927
41PINK11.02621220
42MAP3K121.01299545
43MAP2K31.00393152
44MAP3K140.99326641
45ERBB20.98851119
46TYRO30.98778697
47CDK120.98494078
48MATK0.98466573
49MAPK40.97451117
50JAK10.95791133
51PDK20.95018175
52MET0.93431248
53CDC42BPA0.91805312
54PRKCZ0.91315282
55MAP3K110.90464211
56MAP3K30.86658715
57EPHB10.84006268
58MAPK150.83112677
59FGFR10.82247743
60CAMK1D0.80235452
61RIPK10.79860394
62CDK60.79860171
63PRKACG0.79209767
64STK38L0.77323731
65MAP2K60.76065915
66CSK0.75734862
67MAPK120.75381959
68DYRK1B0.75128496
69CAMK2G0.72768608
70TIE10.70018619
71EEF2K0.67867257
72MAPKAPK30.67427779
73WNK10.67388639
74PRKAA10.66415361
75EPHA30.66090235
76GSK3A0.64653832
77KSR20.62040749
78SMG10.61954148
79IRAK30.61461728
80PTK20.57964172
81PRPF4B0.57134340
82SGK30.56662415
83PDPK10.55700043
84MYLK0.55298206
85IKBKE0.54154408
86SRC0.53829872
87OXSR10.53590365
88PRKCQ0.52976281
89NLK0.52804606
90CSF1R0.52716974
91EPHA40.52094921
92MAPK70.50616977
93FGFR30.49762250
94TGFBR20.48828766
95MAP2K10.48538493
96TAOK10.48163808
97PIK3CA0.46527894
98TAOK20.46465201
99FGR0.46286396
100CSNK1G10.46111287
101GRK10.46059704
102FER0.45490578
103IGF1R0.44970286
104ICK0.42660743
105CAMK2D0.42403492
106RET0.41352527
107MAP3K50.40672370
108PBK0.40627071
109CDK40.39279082
110MAP3K130.39080124
111RIPK40.38894250
112PDK10.37074698
113TESK10.36819294
114YES10.36370908
115PRKCG0.35597999
116SGK20.35497070
117SGK10.33784513
118MTOR0.33186472
119MAPKAPK20.32891511
120MAP2K20.32811986
121CAMK40.32156459
122RPS6KB10.31933913
123EGFR0.31932344
124PAK40.31541305
125MAP4K10.31198546
126MAP3K10.30963308
127AKT30.29706527
128MAP3K60.29506162
129PRKCA0.29256336
130BCR0.28595910
131ZAP700.27827810
132FYN0.27762597
133CSNK1G20.27366772
134PKN10.26652289
135BMX0.26083960
136CAMK1G0.25900409
137CSNK1E0.25206828
138CSNK1G30.23965731
139PRKG20.23719951
140PAK30.23559113
141SGK4940.22867281
142SGK2230.22867281
143PDK40.22040399
144PDK30.22040399
145TNIK0.17834352
146CSNK1A10.16885420
147PRKCB0.16425029

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.43948203
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.44909207
3Nitrogen metabolism_Homo sapiens_hsa009103.40358983
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.17544227
5Arginine biosynthesis_Homo sapiens_hsa002202.95729273
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.81750976
7Tryptophan metabolism_Homo sapiens_hsa003802.72306737
8Complement and coagulation cascades_Homo sapiens_hsa046102.63700639
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.57284523
10Fatty acid degradation_Homo sapiens_hsa000712.54311849
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.42989033
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.37761369
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.30266672
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.24877155
15Butanoate metabolism_Homo sapiens_hsa006502.18036589
16Peroxisome_Homo sapiens_hsa041462.10659934
17Chemical carcinogenesis_Homo sapiens_hsa052042.03302935
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.02501879
19Propanoate metabolism_Homo sapiens_hsa006401.93789255
20Histidine metabolism_Homo sapiens_hsa003401.93269024
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.91573267
22Fatty acid metabolism_Homo sapiens_hsa012121.87080247
23* PPAR signaling pathway_Homo sapiens_hsa033201.85290114
24Caffeine metabolism_Homo sapiens_hsa002321.82707578
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.79803967
26Retinol metabolism_Homo sapiens_hsa008301.75271037
27beta-Alanine metabolism_Homo sapiens_hsa004101.73611220
28Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.69444711
29Staphylococcus aureus infection_Homo sapiens_hsa051501.66697947
30Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.63532346
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.62247623
32Bile secretion_Homo sapiens_hsa049761.53678662
33Selenocompound metabolism_Homo sapiens_hsa004501.51791045
34Phenylalanine metabolism_Homo sapiens_hsa003601.49689571
352-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45782774
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41192965
37Pyruvate metabolism_Homo sapiens_hsa006201.40248575
38Fatty acid elongation_Homo sapiens_hsa000621.39588736
39Tyrosine metabolism_Homo sapiens_hsa003501.39021244
40Starch and sucrose metabolism_Homo sapiens_hsa005001.38888571
41Sulfur metabolism_Homo sapiens_hsa009201.35972483
42Folate biosynthesis_Homo sapiens_hsa007901.28370866
43* Fat digestion and absorption_Homo sapiens_hsa049751.28012897
44ABC transporters_Homo sapiens_hsa020101.22894561
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.22294027
46Steroid biosynthesis_Homo sapiens_hsa001001.18695512
47Biosynthesis of amino acids_Homo sapiens_hsa012301.14508759
48Carbon metabolism_Homo sapiens_hsa012001.13474808
49Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.11912991
50Maturity onset diabetes of the young_Homo sapiens_hsa049501.09903718
51Other glycan degradation_Homo sapiens_hsa005111.08683488
52Vitamin digestion and absorption_Homo sapiens_hsa049771.02254535
53Cyanoamino acid metabolism_Homo sapiens_hsa004601.01393733
54Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.99583111
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99286719
56Arginine and proline metabolism_Homo sapiens_hsa003300.98432531
57Vitamin B6 metabolism_Homo sapiens_hsa007500.90423410
58Sulfur relay system_Homo sapiens_hsa041220.90066711
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88469134
60Protein digestion and absorption_Homo sapiens_hsa049740.86097601
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.83126954
62Lysine degradation_Homo sapiens_hsa003100.82372523
63Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76490587
64Glutathione metabolism_Homo sapiens_hsa004800.74724240
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74377407
66Glycerolipid metabolism_Homo sapiens_hsa005610.73245459
67One carbon pool by folate_Homo sapiens_hsa006700.67047639
68Fatty acid biosynthesis_Homo sapiens_hsa000610.60298015
69Pentose phosphate pathway_Homo sapiens_hsa000300.59142690
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50323995
71Metabolic pathways_Homo sapiens_hsa011000.45499694
72Pertussis_Homo sapiens_hsa051330.39582777
73Pancreatic secretion_Homo sapiens_hsa049720.39376167
74Galactose metabolism_Homo sapiens_hsa000520.38746494
75Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.36771008
76Sphingolipid metabolism_Homo sapiens_hsa006000.36764632
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35844572
78Fructose and mannose metabolism_Homo sapiens_hsa000510.31111207
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30027857
80Prion diseases_Homo sapiens_hsa050200.28816676
81Linoleic acid metabolism_Homo sapiens_hsa005910.23468992
82Insulin resistance_Homo sapiens_hsa049310.21492127
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.20151989
84Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17922717
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.17458010
86N-Glycan biosynthesis_Homo sapiens_hsa005100.12982395
87Glucagon signaling pathway_Homo sapiens_hsa049220.08540711
88Tight junction_Homo sapiens_hsa045300.02653892
89Renin secretion_Homo sapiens_hsa049240.01856088
90AMPK signaling pathway_Homo sapiens_hsa041520.00696775
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.00014661
92Ether lipid metabolism_Homo sapiens_hsa00565-0.2367826
93Type II diabetes mellitus_Homo sapiens_hsa04930-0.2315351
94Bladder cancer_Homo sapiens_hsa05219-0.2311819
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.2209933
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2145952
97Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.2013039
98Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1949572
99Mineral absorption_Homo sapiens_hsa04978-0.1870029
100Hepatitis C_Homo sapiens_hsa05160-0.1774855
101Regulation of autophagy_Homo sapiens_hsa04140-0.1742197
102Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1695747
103Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1482952
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1444012
105Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1428657
106Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1245610
107African trypanosomiasis_Homo sapiens_hsa05143-0.1211894
108Insulin signaling pathway_Homo sapiens_hsa04910-0.1058975
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0831947
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0336954
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0201461
112Renin-angiotensin system_Homo sapiens_hsa04614-0.0191830
113Leukocyte transendothelial migration_Homo sapiens_hsa04670-0.0053907
114Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961-0.0031098

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »