FABP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)9.29073641
2cardiac myofibril assembly (GO:0055003)8.54872519
3negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.87705163
4myofibril assembly (GO:0030239)7.60286194
5tricarboxylic acid cycle (GO:0006099)7.17553856
6negative regulation of potassium ion transmembrane transport (GO:1901380)7.10585269
7actin-myosin filament sliding (GO:0033275)6.61074459
8muscle filament sliding (GO:0030049)6.61074459
9positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.57428783
10cardiac muscle contraction (GO:0060048)6.57142071
11regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.48318708
12cardiac muscle cell development (GO:0055013)6.40014462
13plasma membrane repair (GO:0001778)6.28872826
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.15747575
15regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.09734425
16cardiac cell development (GO:0055006)5.97598096
17adult heart development (GO:0007512)5.94013273
18regulation of actin filament-based movement (GO:1903115)5.85034934
19ventricular cardiac muscle tissue morphogenesis (GO:0055010)5.80961083
20ventricular cardiac muscle cell action potential (GO:0086005)5.77609073
21skeletal muscle contraction (GO:0003009)5.77285539
22cardiac muscle tissue morphogenesis (GO:0055008)5.77130985
23regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.74377531
24ATP synthesis coupled proton transport (GO:0015986)5.71735732
25energy coupled proton transport, down electrochemical gradient (GO:0015985)5.71735732
26actomyosin structure organization (GO:0031032)5.71397749
27regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.68065879
28bundle of His cell to Purkinje myocyte communication (GO:0086069)5.59335401
29regulation of relaxation of muscle (GO:1901077)5.56068961
30actin-mediated cell contraction (GO:0070252)5.40141554
31cardiac muscle hypertrophy (GO:0003300)5.37739221
32regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.34148156
33carnitine shuttle (GO:0006853)5.31934044
34regulation of acyl-CoA biosynthetic process (GO:0050812)5.29976079
35mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.24016971
36regulation of skeletal muscle contraction (GO:0014819)5.23969508
37heart trabecula formation (GO:0060347)5.17659680
38muscle tissue morphogenesis (GO:0060415)5.12651691
39respiratory electron transport chain (GO:0022904)5.12226114
40heart contraction (GO:0060047)5.11949836
41heart process (GO:0003015)5.11949836
42regulation of sarcomere organization (GO:0060297)5.10057809
43striated muscle hypertrophy (GO:0014897)5.08466558
44striated muscle contraction (GO:0006941)5.04096999
45electron transport chain (GO:0022900)4.97456294
46response to inactivity (GO:0014854)4.96778021
47regulation of cofactor metabolic process (GO:0051193)4.85542906
48regulation of coenzyme metabolic process (GO:0051196)4.85542906
49NADH metabolic process (GO:0006734)4.80713113
50regulation of striated muscle contraction (GO:0006942)4.76638305
51regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.76139547
52regulation of the force of heart contraction (GO:0002026)4.75457151
53oxidative phosphorylation (GO:0006119)4.67134322
54cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.62114647
55regulation of cell communication by electrical coupling (GO:0010649)4.60821754
56cell communication involved in cardiac conduction (GO:0086065)4.57213371
57sarcoplasmic reticulum calcium ion transport (GO:0070296)4.55660296
58fatty acid transmembrane transport (GO:1902001)4.54419433
59regulation of membrane repolarization (GO:0060306)4.52620747
60muscle hypertrophy (GO:0014896)4.46558631
61regulation of cardioblast differentiation (GO:0051890)4.35437824
62response to muscle activity (GO:0014850)4.20656682
63muscle system process (GO:0003012)4.20476115
64membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.17918746
65carnitine transmembrane transport (GO:1902603)4.16308038
66regulation of ATP catabolic process (GO:1903289)4.11911934
67regulation of ATPase activity (GO:0043462)4.11911934
68cardiac chamber formation (GO:0003207)4.04555442
69regulation of cardiac muscle contraction (GO:0055117)4.03439780
70negative regulation of protein localization to cell surface (GO:2000009)4.03288978
71cardiac muscle cell action potential involved in contraction (GO:0086002)4.02820321
72regulation of heart rate (GO:0002027)3.99501988
73negative regulation of potassium ion transport (GO:0043267)3.99163107
74cardiac muscle hypertrophy in response to stress (GO:0014898)3.98993491
75muscle hypertrophy in response to stress (GO:0003299)3.98993491
76cardiac muscle adaptation (GO:0014887)3.98993491
77actin filament-based movement (GO:0030048)3.98012135
78cardiac muscle cell action potential (GO:0086001)3.96064478
79cell communication by electrical coupling (GO:0010644)3.95697622
80regulation of cardiac muscle cell contraction (GO:0086004)3.93468354
81striated muscle adaptation (GO:0014888)3.93188311
82ventricular cardiac muscle cell development (GO:0055015)3.91362694
83positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.89547399
84detection of calcium ion (GO:0005513)3.88726775
85cardiac ventricle formation (GO:0003211)3.88719454
86regulation of sulfur metabolic process (GO:0042762)3.88665603
87creatine metabolic process (GO:0006600)3.87871195
88response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.85865901
89regulation of sequestering of triglyceride (GO:0010889)3.85785833
90oxygen transport (GO:0015671)3.85695958
91carnitine transport (GO:0015879)3.84580450
92amino-acid betaine transport (GO:0015838)3.84580450
932-oxoglutarate metabolic process (GO:0006103)3.81834053
94negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.73321594
95regulation of heart contraction (GO:0008016)3.69422882
96negative regulation of striated muscle cell apoptotic process (GO:0010664)3.69123061
97ATP biosynthetic process (GO:0006754)3.64781484
98regulation of muscle contraction (GO:0006937)3.60153238
99negative regulation of calcium ion transmembrane transport (GO:1903170)3.57526154
100negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.57526154
101negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.56124136
102response to epinephrine (GO:0071871)3.54039654
103striated muscle cell development (GO:0055002)3.53878059
104neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.52107360
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.51389588
106cardiac conduction (GO:0061337)3.43766395
107relaxation of cardiac muscle (GO:0055119)3.42806054
108succinate metabolic process (GO:0006105)3.41792064
109positive regulation of heart rate (GO:0010460)3.41463974
110oxaloacetate metabolic process (GO:0006107)3.41185484
111regulation of muscle system process (GO:0090257)3.40907360
112positive regulation of cation channel activity (GO:2001259)3.40733636
113cellular response to epinephrine stimulus (GO:0071872)3.39885135
114regulation of heart rate by cardiac conduction (GO:0086091)3.37523848
115positive regulation of heart contraction (GO:0045823)3.34309005
116regulation of calcium ion transmembrane transporter activity (GO:1901019)3.30540217
117regulation of calcium ion transmembrane transport (GO:1903169)3.30540217
118muscle contraction (GO:0006936)3.29910578
119muscle fiber development (GO:0048747)3.27500714
120muscle adaptation (GO:0043500)3.26200832
121muscle cell cellular homeostasis (GO:0046716)3.22799423
122regulation of cation channel activity (GO:2001257)3.14798027
123response to caffeine (GO:0031000)3.14689489
124mitochondrial genome maintenance (GO:0000002)3.10978828
125skeletal muscle adaptation (GO:0043501)3.05268491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.38982743
2* ESRRB_18555785_ChIP-Seq_MESCs_Mouse5.46070036
3EP300_21415370_ChIP-Seq_HL-1_Mouse4.46393804
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.15481911
5ZNF263_19887448_ChIP-Seq_K562_Human4.06900720
6* TBX20_22328084_ChIP-Seq_HEART_Mouse3.78382447
7* TBX20_22080862_ChIP-Seq_HEART_Mouse3.78382447
8RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.68404293
9MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.88240642
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.79263633
11CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.70713184
12ESR1_20079471_ChIP-ChIP_T-47D_Human2.47661850
13* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.45776642
14GATA4_21415370_ChIP-Seq_HL-1_Mouse2.36491025
15TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.21726005
16ESR2_21235772_ChIP-Seq_MCF-7_Human2.07036064
17PPARD_23208498_ChIP-Seq_MDA-MB-231_Human2.06327503
18EZH2_22144423_ChIP-Seq_EOC_Human1.94186148
19* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.88740178
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.87252634
21NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.76625953
22GATA1_22025678_ChIP-Seq_K562_Human1.69928147
23* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.60740537
24* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.59610493
25EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.57613462
26NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.55293764
27CLOCK_20551151_ChIP-Seq_293T_Human1.53698130
28ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.50878530
29BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.50589324
30ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.50154342
31NFIB_24661679_ChIP-Seq_LUNG_Mouse1.47403962
32FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.47058408
33CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.42872932
34EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.38620126
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.37651593
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36507961
37ATF3_27146783_Chip-Seq_COLON_Human1.35294804
38SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.32362827
39TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29529797
40SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.29134267
41SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.29101310
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28734475
43MTF2_20144788_ChIP-Seq_MESCs_Mouse1.28202694
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.28187435
45PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.27364639
46* TP63_22573176_ChIP-Seq_HFKS_Human1.26003847
47TRIM28_21343339_ChIP-Seq_HEK293_Human1.25525402
48RARB_27405468_Chip-Seq_BRAIN_Mouse1.24569378
49EZH2_27294783_Chip-Seq_ESCs_Mouse1.22630858
50NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.21341084
51GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.20836444
52* CTCF_27219007_Chip-Seq_Bcells_Human1.20175320
53* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18821533
54RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16152484
55EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16152484
56RACK7_27058665_Chip-Seq_MCF-7_Human1.16044678
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.13602983
58LXR_22292898_ChIP-Seq_THP-1_Human1.12516042
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12226233
60RUNX1_27514584_Chip-Seq_MCF-7_Human1.09299099
61BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.06166021
62TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05694709
63NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.05500700
64P68_20966046_ChIP-Seq_HELA_Human1.04805659
65KDM2B_26808549_Chip-Seq_SUP-B15_Human1.04054758
66SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03483976
67SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.03289341
68* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00729155
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.00625504
70YY1_21170310_ChIP-Seq_MESCs_Mouse0.99409662
71SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.99209512
72YY1_22570637_ChIP-Seq_MALME-3M_Human0.99120151
73EZH2_27304074_Chip-Seq_ESCs_Mouse0.99108207
74SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.97781667
75ESR1_21235772_ChIP-Seq_MCF-7_Human0.97375976
76ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.96779036
77RXR_22158963_ChIP-Seq_LIVER_Mouse0.96536479
78PPARA_22158963_ChIP-Seq_LIVER_Mouse0.95682280
79ELK3_25401928_ChIP-Seq_HUVEC_Human0.95187261
80PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93631444
81FOXH1_21741376_ChIP-Seq_ESCs_Human0.93142454
82SMC3_22415368_ChIP-Seq_MEFs_Mouse0.93088213
83WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92150317
84* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.91750404
85SPI1_20517297_ChIP-Seq_HL60_Human0.91160704
86SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.89660571
87RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.89186134
88BCL6_27268052_Chip-Seq_Bcells_Human0.88820943
89SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.88330279
90* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88206631
91JARID2_20075857_ChIP-Seq_MESCs_Mouse0.88025033
92HIF1A_21447827_ChIP-Seq_MCF-7_Human0.86347912
93TBX5_21415370_ChIP-Seq_HL-1_Mouse0.86236974
94CREB1_15753290_ChIP-ChIP_HEK293T_Human0.86151771
95GATA1_19941826_ChIP-Seq_K562_Human0.85840728
96* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85056317
97ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84856134
98E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.84274189
99PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.84130741
100GF1_26923725_Chip-Seq_HPCs_Mouse0.83137368
101BCOR_27268052_Chip-Seq_Bcells_Human0.82851472
102* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.82800861
103* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.82037524
104SMAD4_21741376_ChIP-Seq_HESCs_Human0.81794496
105NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.80998928
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.80998928
107* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.80685586
108* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.80549412
109SALL4_18804426_ChIP-ChIP_XEN_Mouse0.80432831
110* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.80199264
111DROSHA_22980978_ChIP-Seq_HELA_Human0.80027263
112TP53_23651856_ChIP-Seq_MEFs_Mouse0.79645837
113STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.79445759
114RAD21_21589869_ChIP-Seq_MESCs_Mouse0.79428153
115WT1_19549856_ChIP-ChIP_CCG9911_Human0.78765824
116STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.78263756
117DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78181940
118SOX2_21211035_ChIP-Seq_LN229_Gbm0.78124267
119SOX9_24532713_ChIP-Seq_HFSC_Mouse0.78031526
120NANOG_21062744_ChIP-ChIP_HESCs_Human0.77951652
121CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.77895837
122ERG_21242973_ChIP-ChIP_JURKAT_Human0.77320325
123ISL1_27105846_Chip-Seq_CPCs_Mouse0.77272212
124OCT4_20526341_ChIP-Seq_ESCs_Human0.77052110
125KDM2B_26808549_Chip-Seq_DND41_Human0.76903374
126CREB1_26743006_Chip-Seq_LNCaP_Human0.76842804
127THAP11_20581084_ChIP-Seq_MESCs_Mouse0.76653287
128VDR_22108803_ChIP-Seq_LS180_Human0.76324425
129E2F1_20622854_ChIP-Seq_HELA_Human0.75880060
130TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.75769616
131LXR_22158963_ChIP-Seq_LIVER_Mouse0.75638264
132CTCF_21964334_Chip-Seq_Bcells_Human0.75124690
133TET1_21451524_ChIP-Seq_MESCs_Mouse0.74473095
134PCGF2_27294783_Chip-Seq_NPCs_Mouse0.74068926
135MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.73801071
136* SMC4_20622854_ChIP-Seq_HELA_Human0.73545981
137SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.73464936
138AUTS2_25519132_ChIP-Seq_293T-REX_Human0.73455672
139SMAD3_21741376_ChIP-Seq_HESCs_Human0.72599221
140BP1_19119308_ChIP-ChIP_Hs578T_Human0.72457593
141SUZ12_27294783_Chip-Seq_ESCs_Mouse0.71487088
142SMAD4_21799915_ChIP-Seq_A2780_Human0.70318026
143HTT_18923047_ChIP-ChIP_STHdh_Human0.70307416
144EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.69788253
145MYC_27129775_Chip-Seq_CORNEA_Mouse0.69670277
146GBX2_23144817_ChIP-Seq_PC3_Human0.69396485
147WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.67969923
148SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.67964153
149GATA1_19941827_ChIP-Seq_MEL_Mouse0.67663510
150EED_16625203_ChIP-ChIP_MESCs_Mouse0.67389434
151YAP1_20516196_ChIP-Seq_MESCs_Mouse0.66495557

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis7.48563123
2MP0003646_muscle_fatigue5.98393721
3MP0004084_abnormal_cardiac_muscle5.95977910
4MP0000751_myopathy5.03377457
5MP0004215_abnormal_myocardial_fiber4.86236645
6MP0004036_abnormal_muscle_relaxation4.24491312
7MP0005330_cardiomyopathy3.95026300
8MP0000749_muscle_degeneration3.61230323
9MP0002972_abnormal_cardiac_muscle3.13632755
10MP0004087_abnormal_muscle_fiber2.98221702
11MP0003137_abnormal_impulse_conducting2.92009579
12MP0008775_abnormal_heart_ventricle2.87168365
13MP0000750_abnormal_muscle_regeneration2.74363411
14* MP0005385_cardiovascular_system_phenoty2.59283331
15* MP0001544_abnormal_cardiovascular_syste2.59283331
16MP0005620_abnormal_muscle_contractility2.58888925
17MP0006138_congestive_heart_failure2.56036612
18MP0010630_abnormal_cardiac_muscle2.53530363
19MP0004484_altered_response_of2.50231325
20MP0002106_abnormal_muscle_physiology2.37669926
21MP0003828_pulmonary_edema2.32869408
22MP0002269_muscular_atrophy2.30650256
23MP0004085_abnormal_heartbeat2.14402347
24MP0003221_abnormal_cardiomyocyte_apopto1.95216486
25* MP0004130_abnormal_muscle_cell1.93597064
26MP0005369_muscle_phenotype1.92571137
27MP0006036_abnormal_mitochondrial_physio1.89681799
28MP0000747_muscle_weakness1.85148253
29MP0000759_abnormal_skeletal_muscle1.82874791
30MP0004145_abnormal_muscle_electrophysio1.82675739
31MP0004233_abnormal_muscle_weight1.71150999
32MP0003950_abnormal_plasma_membrane1.64087397
33MP0002127_abnormal_cardiovascular_syste1.62145688
34MP0004510_myositis1.55115446
35MP0002332_abnormal_exercise_endurance1.52530460
36MP0005670_abnormal_white_adipose1.48141109
37MP0005666_abnormal_adipose_tissue1.46722683
38MP0003567_abnormal_fetal_cardiomyocyte1.29465960
39MP0006035_abnormal_mitochondrial_morpho1.28010380
40MP0001881_abnormal_mammary_gland1.10893959
41MP0000343_altered_response_to1.09630920
42MP0005165_increased_susceptibility_to1.07837041
43* MP0000266_abnormal_heart_morphology1.06660083
44MP0004185_abnormal_adipocyte_glucose1.00928950
45MP0002234_abnormal_pharynx_morphology0.99879173
46MP0004270_analgesia0.98958960
47MP0005375_adipose_tissue_phenotype0.98302119
48MP0005266_abnormal_metabolism0.92928849
49MP0003279_aneurysm0.90032562
50MP0010368_abnormal_lymphatic_system0.87364729
51MP0005623_abnormal_meninges_morphology0.85234188
52MP0003806_abnormal_nucleotide_metabolis0.84344308
53MP0003566_abnormal_cell_adhesion0.77646541
54MP0001661_extended_life_span0.76997359
55MP0000230_abnormal_systemic_arterial0.76535589
56MP0002108_abnormal_muscle_morphology0.74000904
57MP0003705_abnormal_hypodermis_morpholog0.70809666
58MP0002128_abnormal_blood_circulation0.69820806
59MP0002909_abnormal_adrenal_gland0.68633981
60MP0009840_abnormal_foam_cell0.67256951
61MP0008569_lethality_at_weaning0.66030705
62MP0000013_abnormal_adipose_tissue0.63672257
63MP0004043_abnormal_pH_regulation0.60724335
64MP0000003_abnormal_adipose_tissue0.57896047
65MP0009780_abnormal_chondrocyte_physiolo0.57004524
66MP0008004_abnormal_stomach_pH0.56075769
67MP0004272_abnormal_basement_membrane0.55923260
68MP0005187_abnormal_penis_morphology0.55606386
69MP0003984_embryonic_growth_retardation0.55279336
70MP0001727_abnormal_embryo_implantation0.54303220
71MP0002088_abnormal_embryonic_growth/wei0.54042133
72MP0003195_calcinosis0.47982131
73MP0005319_abnormal_enzyme/_coenzyme0.47133108
74MP0000767_abnormal_smooth_muscle0.46201675
75MP0002971_abnormal_brown_adipose0.44692045
76MP0005584_abnormal_enzyme/coenzyme_acti0.43389894
77MP0003045_fibrosis0.43359427
78MP0001984_abnormal_olfaction0.43061981
79MP0005451_abnormal_body_composition0.42708102
80MP0001299_abnormal_eye_distance/0.42017034
81MP0001879_abnormal_lymphatic_vessel0.41884131
82MP0005535_abnormal_body_temperature0.41843196
83MP0004147_increased_porphyrin_level0.41693726
84* MP0002078_abnormal_glucose_homeostasis0.40522993
85MP0009384_cardiac_valve_regurgitation0.40504522
86MP0003329_amyloid_beta_deposits0.39871239
87MP0008874_decreased_physiological_sensi0.39212027
88MP0002925_abnormal_cardiovascular_devel0.39201249
89MP0005380_embryogenesis_phenotype0.37399398
90MP0001672_abnormal_embryogenesis/_devel0.37399398
91MP0003879_abnormal_hair_cell0.36835627
92MP0002295_abnormal_pulmonary_circulatio0.36288433
93MP0002822_catalepsy0.36138600
94MP0003941_abnormal_skin_development0.33689924
95MP0004859_abnormal_synaptic_plasticity0.33550208
96MP0005332_abnormal_amino_acid0.33024759
97MP0000358_abnormal_cell_content/0.33011203
98MP0000733_abnormal_muscle_development0.32867950
99MP0001784_abnormal_fluid_regulation0.32211426
100MP0001958_emphysema0.30784747
101MP0003948_abnormal_gas_homeostasis0.30296038
102MP0002272_abnormal_nervous_system0.28947876
103MP0002638_abnormal_pupillary_reflex0.28770325
104MP0001614_abnormal_blood_vessel0.28257542
105MP0005167_abnormal_blood-brain_barrier0.28070691
106MP0005595_abnormal_vascular_smooth0.27556308
107MP0002734_abnormal_mechanical_nocicepti0.27485939
108MP0005452_abnormal_adipose_tissue0.27481935
109MP0003878_abnormal_ear_physiology0.26812797
110MP0005377_hearing/vestibular/ear_phenot0.26812797
111* MP0005386_behavior/neurological_phenoty0.26348987
112* MP0004924_abnormal_behavior0.26348987
113MP0001440_abnormal_grooming_behavior0.26277715
114MP0002254_reproductive_system_inflammat0.25563815
115MP0002064_seizures0.25131867
116MP0005376_homeostasis/metabolism_phenot0.25070976
117MP0008438_abnormal_cutaneous_collagen0.24505663
118MP0001756_abnormal_urination0.24287696
119MP0009745_abnormal_behavioral_response0.24206990
120MP0002066_abnormal_motor_capabilities/c0.24206024
121MP0009115_abnormal_fat_cell0.23933573
122MP0002090_abnormal_vision0.23096768
123MP0005334_abnormal_fat_pad0.22607779
124* MP0002118_abnormal_lipid_homeostasis0.22528537
125MP0005083_abnormal_biliary_tract0.22394409
126MP0005275_abnormal_skin_tensile0.22103637
127MP0008961_abnormal_basal_metabolism0.21519000
128MP0001529_abnormal_vocalization0.21338771
129MP0001765_abnormal_ion_homeostasis0.20373208

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)8.14371547
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)7.10100331
3Muscle fiber inclusion bodies (HP:0100299)7.09380723
4Ventricular tachycardia (HP:0004756)7.00692910
5Nemaline bodies (HP:0003798)6.85393089
6Calf muscle hypertrophy (HP:0008981)6.14771281
7Atrial fibrillation (HP:0005110)5.91359121
8Muscle fiber splitting (HP:0003555)5.80829531
9Muscle hypertrophy of the lower extremities (HP:0008968)5.58569383
10Primary atrial arrhythmia (HP:0001692)5.55272499
11Supraventricular tachycardia (HP:0004755)5.38170698
12Exercise-induced muscle cramps (HP:0003710)5.36371515
13Lipoatrophy (HP:0100578)5.32645011
14Exercise-induced myalgia (HP:0003738)5.29809644
15Supraventricular arrhythmia (HP:0005115)5.28633888
16Abnormality of the calf musculature (HP:0001430)5.04793758
17Right ventricular cardiomyopathy (HP:0011663)4.91849474
18Abnormality of the left ventricular outflow tract (HP:0011103)4.85375515
19Subaortic stenosis (HP:0001682)4.85375515
20Hyporeflexia of lower limbs (HP:0002600)4.74776620
21Syncope (HP:0001279)4.71616552
22Palpitations (HP:0001962)4.59125042
23Bundle branch block (HP:0011710)4.53715900
24Myoglobinuria (HP:0002913)4.46084751
25Dilated cardiomyopathy (HP:0001644)4.42634450
26Prolonged QT interval (HP:0001657)4.20804701
27Centrally nucleated skeletal muscle fibers (HP:0003687)4.18719053
28EMG: myopathic abnormalities (HP:0003458)4.07166140
29Asymmetric septal hypertrophy (HP:0001670)3.92747770
30Ventricular arrhythmia (HP:0004308)3.91234377
31Acute necrotizing encephalopathy (HP:0006965)3.81798322
32Increased connective tissue (HP:0009025)3.80788499
33Abnormal mitochondria in muscle tissue (HP:0008316)3.75768676
34Heart block (HP:0012722)3.73184348
35Ventricular fibrillation (HP:0001663)3.63566772
36Atrioventricular block (HP:0001678)3.62262267
37Hepatic necrosis (HP:0002605)3.55039154
38Abnormal atrioventricular conduction (HP:0005150)3.52332343
39Rhabdomyolysis (HP:0003201)3.45935223
40Difficulty running (HP:0009046)3.43550765
41Myotonia (HP:0002486)3.38443909
42Acute encephalopathy (HP:0006846)3.24732146
43Hepatocellular necrosis (HP:0001404)3.18857893
44Myopathic facies (HP:0002058)3.17509465
45Mitochondrial inheritance (HP:0001427)3.14144745
46Progressive macrocephaly (HP:0004481)3.12900016
47Difficulty climbing stairs (HP:0003551)3.11933302
48Distal arthrogryposis (HP:0005684)3.08234559
49Abnormal EKG (HP:0003115)3.05253982
50Mildly elevated creatine phosphokinase (HP:0008180)2.96346167
51Increased CSF lactate (HP:0002490)2.93087637
52Cerebral edema (HP:0002181)2.90423155
53Left ventricular hypertrophy (HP:0001712)2.89587301
54Generalized muscle weakness (HP:0003324)2.85679900
55Round ear (HP:0100830)2.81940501
56Palmoplantar keratoderma (HP:0000982)2.74861875
57Ketoacidosis (HP:0001993)2.74385629
58Testicular atrophy (HP:0000029)2.72899948
59Increased muscle lipid content (HP:0009058)2.68080384
60Frequent falls (HP:0002359)2.67766394
61Hypoglycemic coma (HP:0001325)2.63220307
62Distal lower limb muscle weakness (HP:0009053)2.60023561
63Dicarboxylic aciduria (HP:0003215)2.59721206
64Abnormality of dicarboxylic acid metabolism (HP:0010995)2.59721206
65Lower limb amyotrophy (HP:0007210)2.59450065
66Respiratory failure (HP:0002878)2.56639305
67Ragged-red muscle fibers (HP:0003200)2.52631382
68Ulnar deviation of the wrist (HP:0003049)2.51389968
69Lactic acidosis (HP:0003128)2.50507965
70Abnormality of fatty-acid metabolism (HP:0004359)2.48535412
71Exercise intolerance (HP:0003546)2.47486106
72Areflexia of lower limbs (HP:0002522)2.43025364
73Increased intramyocellular lipid droplets (HP:0012240)2.42116053
74Conjunctival hamartoma (HP:0100780)2.39102679
75Neck muscle weakness (HP:0000467)2.38718045
76Gowers sign (HP:0003391)2.38631742
77Scapular winging (HP:0003691)2.37787863
78Bulbar palsy (HP:0001283)2.36784188
79Muscle stiffness (HP:0003552)2.32711912
80Limb-girdle muscle atrophy (HP:0003797)2.32596111
81Pheochromocytoma (HP:0002666)2.31752646
82Athetosis (HP:0002305)2.30243557
83Increased variability in muscle fiber diameter (HP:0003557)2.26858096
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.16307005
85Abnormality of alanine metabolism (HP:0010916)2.16307005
86Hyperalaninemia (HP:0003348)2.16307005
87Progressive muscle weakness (HP:0003323)2.12748632
88Lipid accumulation in hepatocytes (HP:0006561)2.08385583
89Abnormality of the foot musculature (HP:0001436)2.07915154
90Neuroendocrine neoplasm (HP:0100634)2.07369897
91Double outlet right ventricle (HP:0001719)2.06603800
92Congenital malformation of the right heart (HP:0011723)2.06603800
93Abnormality of skeletal muscle fiber size (HP:0012084)2.03955287
94Dysmetric saccades (HP:0000641)2.01923133
95Weak cry (HP:0001612)2.01659598
96Calcaneovalgus deformity (HP:0001848)2.00988941
97Ketosis (HP:0001946)1.97106066
98Sudden cardiac death (HP:0001645)1.95756194
99Foot dorsiflexor weakness (HP:0009027)1.94897352
100Abnormality of the shoulder girdle musculature (HP:0001435)1.94798298
101Rimmed vacuoles (HP:0003805)1.94441890
102Esophageal neoplasm (HP:0100751)1.93846376
103Neoplasm of head and neck (HP:0012288)1.93846376
104Congestive heart failure (HP:0001635)1.93832336
105Hamartoma of the eye (HP:0010568)1.93275076
106Steppage gait (HP:0003376)1.93016115
107Proximal amyotrophy (HP:0007126)1.92131381
108Distal lower limb amyotrophy (HP:0008944)1.90890449
109Neoplasm of the adrenal gland (HP:0100631)1.90045352
110Abnormality of glycolysis (HP:0004366)1.89386401
111Increased serum pyruvate (HP:0003542)1.89386401
112Hypoplastic heart (HP:0001961)1.88848618
113EMG: neuropathic changes (HP:0003445)1.88485186
114Muscular dystrophy (HP:0003560)1.88098902
115Respiratory insufficiency due to muscle weakness (HP:0002747)1.87252154
116Absent phalangeal crease (HP:0006109)1.84143852
117Tinnitus (HP:0000360)1.83934670
118Large for gestational age (HP:0001520)1.83834551
119Type 1 muscle fiber predominance (HP:0003803)1.83205719
120Hyperinsulinemic hypoglycemia (HP:0000825)1.81306976
121Hypoplastic left heart (HP:0004383)1.81221852
122Increased serum lactate (HP:0002151)1.80108657
123Waddling gait (HP:0002515)1.78811415
124Hyperglycinuria (HP:0003108)1.78605626
125Increased hepatocellular lipid droplets (HP:0006565)1.78224175
126Generalized aminoaciduria (HP:0002909)1.77269323
127Deformed tarsal bones (HP:0008119)1.74961870
128Hip contracture (HP:0003273)1.72855575
129Malignant hyperthermia (HP:0002047)1.66987216
130Abnormality of the neuromuscular junction (HP:0003398)1.65517364
131Fatigable weakness (HP:0003473)1.65517364
132Abnormality of the tricuspid valve (HP:0001702)1.63547470
133Aplasia of the musculature (HP:0100854)1.62404383
134Fetal akinesia sequence (HP:0001989)1.61577014
135Spinal rigidity (HP:0003306)1.49671485
136Abnormal finger flexion creases (HP:0006143)1.43846310
137Limb-girdle muscle weakness (HP:0003325)1.43710279
138Skin nodule (HP:0200036)1.43371072
139Bradycardia (HP:0001662)1.41849873

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.67836669
2MYLK4.34995820
3LMTK24.10194283
4PDK34.08256209
5PDK44.08256209
6PHKG23.83826188
7PHKG13.83826188
8OBSCN3.43412354
9NEK12.96431365
10PKN22.75979176
11DMPK2.66777177
12BCKDK2.58970311
13PDK22.56390992
14TRIB32.43858433
15MUSK2.17891763
16PINK12.16075699
17PIK3CA2.13002220
18TIE11.96257528
19PIK3CG1.86223575
20LIMK11.79230194
21STK241.71818074
22MARK11.71365028
23EPHA21.66510510
24PAK31.54650051
25GRK71.45310375
26CAMK2D1.45070055
27ILK1.29014350
28STK38L1.28245991
29CDC42BPA1.27855153
30PRKD11.24744245
31DAPK31.21554231
32NME11.17379578
33MAPKAPK31.10354610
34ROCK11.01580402
35MAPK120.94492080
36ZAK0.94306351
37STK40.93882747
38STK380.92192490
39WNK40.91554781
40MAP3K60.91443222
41MAP3K50.91156559
42PRKAA10.83812940
43NME20.78034236
44PKN10.74098378
45RIPK10.72779845
46ROCK20.71682272
47CAMK2A0.67689796
48PRKAA20.66466803
49CAMK10.65299800
50MAPK40.65088496
51RPS6KC10.64829777
52RPS6KL10.64829777
53MAP3K70.64223921
54KDR0.62171704
55EPHA30.62027946
56MAP3K30.61589421
57CAMK40.61267617
58PRKCE0.59826947
59RPS6KB20.58115330
60MOS0.58023615
61PDGFRA0.55373964
62TESK10.54364141
63MAPK70.53835829
64PTK2B0.53707460
65RPS6KA60.52101661
66PRKACB0.50520125
67KSR20.49977361
68LATS20.49533031
69PRKG10.47607746
70CAMK2G0.47234404
71FLT30.46059022
72MAP2K30.45683791
73ARAF0.45095319
74MAP2K60.44192848
75TRPM70.43472072
76PDPK10.41491149
77PRKACA0.41460107
78FER0.39098303
79PNCK0.38614964
80DAPK20.38054063
81CCNB10.37860162
82ICK0.37524523
83PRKACG0.37415095
84INSRR0.35908006
85ZAP700.35393463
86WNK10.33995894
87EPHB10.33784525
88CAMK1D0.33297532
89UHMK10.32632622
90EEF2K0.30956467
91AKT20.30894160
92MAP3K40.30545960
93EPHA40.29628811
94PDK10.26948276
95CDK50.26944547
96SGK20.25944323
97MARK20.25807000
98TGFBR20.24356983
99CAMK2B0.24051173
100DYRK1B0.23787895
101MAPK100.21956950
102PRPF4B0.21913773
103RPS6KA10.21768802
104MTOR0.21686595
105TAOK20.21183254
106ABL20.18823989
107SGK4940.18818160
108SGK2230.18818160
109DDR20.18736295
110PRKD30.17102068
111MAP3K10.16942874
112CAMK1G0.16815643
113MAP3K110.16588443
114STK390.16552306
115SIK10.15457030
116STK110.14602496
117TAOK10.14280164
118MAP3K120.14272905
119EPHB20.12888628
120PRKG20.12778816
121NEK90.12595551
122ERBB30.12344941
123RPS6KA20.12040149
124RPS6KA30.10795789
125SGK30.09504724
126PTK60.09366847
127MAP2K10.09091908
128RET0.08706732
129MAPKAPK20.08558535
130SGK10.08498462
131GRK50.07990280
132MAP2K40.07976144
133PAK60.07643302
134PRKCD0.07373525

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000206.09788077
2Cardiac muscle contraction_Homo sapiens_hsa042604.50805390
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.40211066
4Oxidative phosphorylation_Homo sapiens_hsa001904.07965226
5Parkinsons disease_Homo sapiens_hsa050123.93550641
6Dilated cardiomyopathy_Homo sapiens_hsa054143.38208211
7Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.29966755
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.21008956
9Propanoate metabolism_Homo sapiens_hsa006403.15989487
10Alzheimers disease_Homo sapiens_hsa050102.86026940
11Huntingtons disease_Homo sapiens_hsa050162.62993595
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.56991835
13Carbon metabolism_Homo sapiens_hsa012002.53228343
14Fatty acid degradation_Homo sapiens_hsa000712.46633212
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.11498041
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.07734180
17Fatty acid metabolism_Homo sapiens_hsa012122.03075890
18Pyruvate metabolism_Homo sapiens_hsa006201.92102881
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.63393393
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56204745
21Viral myocarditis_Homo sapiens_hsa054161.52333497
22Butanoate metabolism_Homo sapiens_hsa006501.31919756
23Fatty acid elongation_Homo sapiens_hsa000621.21875265
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.21824973
25Biosynthesis of amino acids_Homo sapiens_hsa012301.16347596
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04815913
27Fatty acid biosynthesis_Homo sapiens_hsa000611.00084837
28Galactose metabolism_Homo sapiens_hsa000520.92542418
29Glucagon signaling pathway_Homo sapiens_hsa049220.86541853
30Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.86437971
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79194448
32Insulin resistance_Homo sapiens_hsa049310.78585241
33cGMP-PKG signaling pathway_Homo sapiens_hsa040220.78144720
34Insulin signaling pathway_Homo sapiens_hsa049100.77437285
35Fructose and mannose metabolism_Homo sapiens_hsa000510.76247231
36Adipocytokine signaling pathway_Homo sapiens_hsa049200.75777042
37Tight junction_Homo sapiens_hsa045300.70366491
38* PPAR signaling pathway_Homo sapiens_hsa033200.70181526
39Starch and sucrose metabolism_Homo sapiens_hsa005000.68518164
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65031537
41beta-Alanine metabolism_Homo sapiens_hsa004100.64728572
42Arginine biosynthesis_Homo sapiens_hsa002200.64429179
43Calcium signaling pathway_Homo sapiens_hsa040200.64256455
44Arginine and proline metabolism_Homo sapiens_hsa003300.63250322
45HIF-1 signaling pathway_Homo sapiens_hsa040660.60630651
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60405357
47Ovarian steroidogenesis_Homo sapiens_hsa049130.59069034
48AMPK signaling pathway_Homo sapiens_hsa041520.58083770
49Tryptophan metabolism_Homo sapiens_hsa003800.56983864
50Long-term potentiation_Homo sapiens_hsa047200.55040218
51GABAergic synapse_Homo sapiens_hsa047270.51704834
52Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49419818
53Lysine degradation_Homo sapiens_hsa003100.48874405
54Type II diabetes mellitus_Homo sapiens_hsa049300.48726804
55Focal adhesion_Homo sapiens_hsa045100.48441277
56Amphetamine addiction_Homo sapiens_hsa050310.46731595
57Phenylalanine metabolism_Homo sapiens_hsa003600.46705671
58Oxytocin signaling pathway_Homo sapiens_hsa049210.46213602
59Morphine addiction_Homo sapiens_hsa050320.45005953
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.42356146
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42199901
62Metabolic pathways_Homo sapiens_hsa011000.40473160
63Peroxisome_Homo sapiens_hsa041460.39604156
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37724132
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.35953616
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.35794226
67Proteasome_Homo sapiens_hsa030500.34923092
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.33467278
69Gastric acid secretion_Homo sapiens_hsa049710.33392873
70Renin secretion_Homo sapiens_hsa049240.31431990
71Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31048531
72Synaptic vesicle cycle_Homo sapiens_hsa047210.29726516
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.27336793
74Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.26911373
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26749958
76Dopaminergic synapse_Homo sapiens_hsa047280.26050547
77Insulin secretion_Homo sapiens_hsa049110.25835906
78cAMP signaling pathway_Homo sapiens_hsa040240.25758711
79Bile secretion_Homo sapiens_hsa049760.25717308
80Prion diseases_Homo sapiens_hsa050200.25319633
81ECM-receptor interaction_Homo sapiens_hsa045120.24795625
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.24490984
83Adherens junction_Homo sapiens_hsa045200.21756906
84Collecting duct acid secretion_Homo sapiens_hsa049660.21726993
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20875002
86Sulfur relay system_Homo sapiens_hsa041220.19856748
87Fat digestion and absorption_Homo sapiens_hsa049750.19646612
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19613566
89Cocaine addiction_Homo sapiens_hsa050300.18760351
90Nitrogen metabolism_Homo sapiens_hsa009100.18258147
91Glutamatergic synapse_Homo sapiens_hsa047240.18075405
92Melanogenesis_Homo sapiens_hsa049160.17175824
93Circadian entrainment_Homo sapiens_hsa047130.16539546
94Taste transduction_Homo sapiens_hsa047420.16251334
95Amoebiasis_Homo sapiens_hsa051460.15430573
96Circadian rhythm_Homo sapiens_hsa047100.15211486
97Mineral absorption_Homo sapiens_hsa049780.14859983
98Pentose phosphate pathway_Homo sapiens_hsa000300.14744982
99Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.13863515
100Regulation of autophagy_Homo sapiens_hsa041400.13842062
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.13288161
102Aldosterone synthesis and secretion_Homo sapiens_hsa049250.12859470
103Renal cell carcinoma_Homo sapiens_hsa052110.11771566
104Gap junction_Homo sapiens_hsa045400.11310565
105Caffeine metabolism_Homo sapiens_hsa002320.10416926
106mTOR signaling pathway_Homo sapiens_hsa041500.08940630
107Glycerolipid metabolism_Homo sapiens_hsa005610.08589805
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.08097687
109Tyrosine metabolism_Homo sapiens_hsa003500.06530951
110Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.05446781
111Vibrio cholerae infection_Homo sapiens_hsa051100.03240931
112GnRH signaling pathway_Homo sapiens_hsa049120.00532508
113Estrogen signaling pathway_Homo sapiens_hsa04915-0.0360075
114Cholinergic synapse_Homo sapiens_hsa04725-0.0301630
115Salivary secretion_Homo sapiens_hsa04970-0.0292311
116Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0292156
117Ribosome_Homo sapiens_hsa03010-0.0256168
118Proteoglycans in cancer_Homo sapiens_hsa05205-0.0158650
119Pancreatic secretion_Homo sapiens_hsa04972-0.0139634
120VEGF signaling pathway_Homo sapiens_hsa04370-0.0032384

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