FABP4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1low-density lipoprotein particle clearance (GO:0034383)9.47822826
2valine metabolic process (GO:0006573)7.12982209
3* brown fat cell differentiation (GO:0050873)7.11607903
4* triglyceride catabolic process (GO:0019433)6.99683548
5regulation of cholesterol storage (GO:0010885)6.83287396
6diacylglycerol metabolic process (GO:0046339)6.56398128
7positive regulation of fatty acid oxidation (GO:0046321)6.40426525
8* white fat cell differentiation (GO:0050872)6.21320089
9* acylglycerol catabolic process (GO:0046464)6.21319356
10* neutral lipid catabolic process (GO:0046461)6.21319356
11fatty acid transmembrane transport (GO:1902001)5.93034275
12positive regulation of fatty acid beta-oxidation (GO:0032000)5.89575301
13biotin metabolic process (GO:0006768)5.80211329
14negative regulation of macrophage derived foam cell differentiation (GO:0010745)5.73409184
15lipid particle organization (GO:0034389)5.60582228
16lipid storage (GO:0019915)5.44784582
17fatty acid beta-oxidation (GO:0006635)5.42512753
18regulation of fatty acid oxidation (GO:0046320)5.22688043
19carnitine shuttle (GO:0006853)5.16901500
20triglyceride biosynthetic process (GO:0019432)5.13994817
21positive regulation of lipid storage (GO:0010884)5.05755183
22branched-chain amino acid catabolic process (GO:0009083)4.90848500
23acylglycerol biosynthetic process (GO:0046463)4.90586461
24neutral lipid biosynthetic process (GO:0046460)4.90586461
25branched-chain amino acid metabolic process (GO:0009081)4.90405957
26fatty acid oxidation (GO:0019395)4.79962239
27regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)4.73772773
28lipid oxidation (GO:0034440)4.70901005
29* glycerolipid catabolic process (GO:0046503)4.61954248
30polyol transport (GO:0015791)4.57858794
31fatty acid catabolic process (GO:0009062)4.55649292
32CDP-diacylglycerol biosynthetic process (GO:0016024)4.53473330
33regulation of fatty acid beta-oxidation (GO:0031998)4.53470918
34regulation of macrophage derived foam cell differentiation (GO:0010743)4.43246141
35CDP-diacylglycerol metabolic process (GO:0046341)4.33879722
36tricarboxylic acid cycle (GO:0006099)4.29913927
37negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)4.29825841
38response to phenylpropanoid (GO:0080184)4.27827502
39response to dietary excess (GO:0002021)4.26016890
40positive regulation of fatty acid metabolic process (GO:0045923)4.23600133
41NADH metabolic process (GO:0006734)4.15990684
42negative regulation of lipid storage (GO:0010888)4.15541339
43negative regulation of protein autophosphorylation (GO:0031953)4.12015837
44carnitine transmembrane transport (GO:1902603)4.08424302
45protein heterotrimerization (GO:0070208)4.06589011
46ethanol oxidation (GO:0006069)4.06187448
47ovulation from ovarian follicle (GO:0001542)4.05701939
48regulation of lipid storage (GO:0010883)4.05663307
49regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.03739500
50thioester metabolic process (GO:0035383)3.98295459
51acyl-CoA metabolic process (GO:0006637)3.98295459
52thioester biosynthetic process (GO:0035384)3.97675756
53acyl-CoA biosynthetic process (GO:0071616)3.97675756
54positive regulation of lipid catabolic process (GO:0050996)3.93078100
55plasma lipoprotein particle clearance (GO:0034381)3.92142455
56retinol metabolic process (GO:0042572)3.91327879
57phospholipid homeostasis (GO:0055091)3.88592383
58tricarboxylic acid metabolic process (GO:0072350)3.86801984
59coenzyme A biosynthetic process (GO:0015937)3.86437332
60retina vasculature morphogenesis in camera-type eye (GO:0061299)3.84418147
61* triglyceride metabolic process (GO:0006641)3.83602370
62primary alcohol metabolic process (GO:0034308)3.82318826
63alpha-linolenic acid metabolic process (GO:0036109)3.75669515
64positive regulation of cellular response to insulin stimulus (GO:1900078)3.75647283
65carnitine transport (GO:0015879)3.74476722
66amino-acid betaine transport (GO:0015838)3.74476722
67fatty-acyl-CoA metabolic process (GO:0035337)3.72484283
68cGMP-mediated signaling (GO:0019934)3.72229723
69negative regulation of metanephros development (GO:0072217)3.72163782
70negative regulation of granulocyte differentiation (GO:0030853)3.70384890
71fatty-acyl-CoA biosynthetic process (GO:0046949)3.70364001
72acetyl-CoA metabolic process (GO:0006084)3.69530255
73triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.65328981
74response to epinephrine (GO:0071871)3.62703258
75regulation of acyl-CoA biosynthetic process (GO:0050812)3.62689184
76fatty acid homeostasis (GO:0055089)3.62190917
77phosphatidic acid biosynthetic process (GO:0006654)3.61196426
78phosphatidic acid metabolic process (GO:0046473)3.61196426
79* acylglycerol metabolic process (GO:0006639)3.60340190
80regulation of cAMP-dependent protein kinase activity (GO:2000479)3.57142229
81long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.56654758
82positive regulation of lipoprotein lipase activity (GO:0051006)3.56155869
83positive regulation of triglyceride lipase activity (GO:0061365)3.56155869
84positive regulation of glycolytic process (GO:0045821)3.56059812
85* neutral lipid metabolic process (GO:0006638)3.54831709
86alditol metabolic process (GO:0019400)3.53290860
87oxaloacetate metabolic process (GO:0006107)3.53011770
88positive regulation of glucose import (GO:0046326)3.50379890
89long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.48963529
90negative regulation of lipid catabolic process (GO:0050995)3.48561475
91succinate metabolic process (GO:0006105)3.47392520
92protein localization to cell surface (GO:0034394)3.46459517
93L-serine transport (GO:0015825)3.43411366
94cellular response to epinephrine stimulus (GO:0071872)3.43048114
95positive regulation of glomerulus development (GO:0090193)3.42717056
96regulation of triglyceride catabolic process (GO:0010896)3.41724239
97complement activation, alternative pathway (GO:0006957)3.41667348
98negative regulation of DNA biosynthetic process (GO:2000279)3.41122471
99intracellular lipid transport (GO:0032365)3.40930189
100NADPH regeneration (GO:0006740)3.40082853
101monocarboxylic acid catabolic process (GO:0072329)3.39652332
102negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.38612054
103regulation of cofactor metabolic process (GO:0051193)3.37856887
104regulation of coenzyme metabolic process (GO:0051196)3.37856887
105glycerol metabolic process (GO:0006071)3.36925889
106response to hydroperoxide (GO:0033194)3.36656387
107pentose-phosphate shunt (GO:0006098)3.36408869
108linoleic acid metabolic process (GO:0043651)3.36386145
109regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.35875574
110negative regulation of phagocytosis (GO:0050765)3.35626056
111negative regulation of smooth muscle cell migration (GO:0014912)3.35289850
112transcytosis (GO:0045056)3.32967821
113positive regulation of cholesterol efflux (GO:0010875)3.30512929
114positive regulation of cholesterol transport (GO:0032376)3.29960336
115positive regulation of sterol transport (GO:0032373)3.29960336
116long-chain fatty acid transport (GO:0015909)3.28772283
117regulation of glycogen (starch) synthase activity (GO:2000465)3.23597941
118positive regulation of macrophage derived foam cell differentiation (GO:0010744)3.23095640
119regulation of triglyceride biosynthetic process (GO:0010866)3.21182323
120negative regulation of macrophage differentiation (GO:0045650)3.20407387
121positive regulation of macrophage cytokine production (GO:0060907)3.20215591
122acylglycerol homeostasis (GO:0055090)3.19617062
123triglyceride homeostasis (GO:0070328)3.19617062
124apoptotic cell clearance (GO:0043277)3.17437825
125positive regulation of insulin receptor signaling pathway (GO:0046628)3.17116053
1262-oxoglutarate metabolic process (GO:0006103)3.16794487
127growth hormone receptor signaling pathway (GO:0060396)3.15895512
128endocrine hormone secretion (GO:0060986)3.13187830
129regulation of fatty acid metabolic process (GO:0019217)3.12603506
130regulation of cholesterol efflux (GO:0010874)3.12548924
131negative regulation of gluconeogenesis (GO:0045721)3.10544306
132regulation of sequestering of triglyceride (GO:0010889)10.4424328

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse6.99395533
2CLOCK_20551151_ChIP-Seq_293T_Human4.56412153
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.05832281
4RXR_22158963_ChIP-Seq_LIVER_Mouse2.66693777
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.63914271
6STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.55811633
7* LXR_22158963_ChIP-Seq_LIVER_Mouse2.48052794
8PPARG_20176806_ChIP-Seq_3T3-L1_Mouse2.47730909
9TP63_17297297_ChIP-ChIP_HaCaT_Human2.45859362
10PPARA_22158963_ChIP-Seq_LIVER_Mouse2.31399100
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.15444871
12* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse2.08854211
13* PPARG_19300518_ChIP-PET_3T3-L1_Mouse14.8219887
14CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.88362211
15GATA1_22025678_ChIP-Seq_K562_Human1.87621485
16FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.86733028
17NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.86354175
18* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.73587139
19ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.72716094
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.69882316
21ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.69093221
22TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.54281813
23ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.49021601
24* TBX20_22328084_ChIP-Seq_HEART_Mouse1.48310176
25* TBX20_22080862_ChIP-Seq_HEART_Mouse1.48310176
26CDX2_19796622_ChIP-Seq_MESCs_Mouse1.45930146
27ZNF263_19887448_ChIP-Seq_K562_Human1.42459791
28STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.42413955
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.41348873
30EP300_21415370_ChIP-Seq_HL-1_Mouse1.40743439
31PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.39466294
32BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.38735912
33HIF1A_21447827_ChIP-Seq_MCF-7_Human1.37906316
34FOXO3_23340844_ChIP-Seq_DLD1_Human1.32777636
35CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.30760049
36SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.26717376
37SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.25881441
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.23726633
39CJUN_26792858_Chip-Seq_BT549_Human1.18187219
40ESR1_20079471_ChIP-ChIP_T-47D_Human1.17682424
41* GATA2_21666600_ChIP-Seq_HMVEC_Human1.17243255
42* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14962834
43EZH2_22144423_ChIP-Seq_EOC_Human1.11967985
44VDR_24787735_ChIP-Seq_THP-1_Human1.10926560
45Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.10110459
46PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.07419796
47SA1_22415368_ChIP-Seq_MEFs_Mouse1.06588919
48KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04023841
49EZH2_18974828_ChIP-Seq_MESCs_Mouse1.03881353
50RNF2_18974828_ChIP-Seq_MESCs_Mouse1.03881353
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.02793740
52SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97813623
53IRF8_22096565_ChIP-ChIP_GC-B_Human0.97430795
54NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96508038
55NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96508038
56THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96207442
57NFIB_24661679_ChIP-Seq_LUNG_Mouse0.95495394
58BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.95344948
59SOX9_24532713_ChIP-Seq_HFSC_Mouse0.94074344
60MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93440710
61RAD21_21589869_ChIP-Seq_MESCs_Mouse0.93383119
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.93202951
63RXR_22108803_ChIP-Seq_LS180_Human0.90995675
64RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.90245088
65IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.89815848
66EED_16625203_ChIP-ChIP_MESCs_Mouse0.89329651
67SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.86897282
68FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.86580635
69SMC3_22415368_ChIP-Seq_MEFs_Mouse0.86092577
70SMC1_22415368_ChIP-Seq_MEFs_Mouse0.84320699
71PIAS1_25552417_ChIP-Seq_VCAP_Human0.84156299
72SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.83251760
73GATA1_19941826_ChIP-Seq_K562_Human0.83150753
74P300_27058665_Chip-Seq_ZR-75-30cells_Human0.82235010
75SMAD_19615063_ChIP-ChIP_OVARY_Human0.82115045
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.81922843
77EGR1_23403033_ChIP-Seq_LIVER_Mouse0.81481700
78PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.81318496
79P63_26484246_Chip-Seq_KERATINOCYTES_Human0.81315457
80NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.81225548
81CBP_21632823_ChIP-Seq_H3396_Human0.80928875
82SOX2_20726797_ChIP-Seq_SW620_Human0.80882053
83CTNNB1_20460455_ChIP-Seq_HCT116_Human0.79249777
84ELK3_25401928_ChIP-Seq_HUVEC_Human0.78458747
85ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.77522426
86HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.76995900
87DNAJC2_21179169_ChIP-ChIP_NT2_Human0.76311832
88BCAT_22108803_ChIP-Seq_LS180_Human0.75460826
89LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.75259365
90FOXA2_19822575_ChIP-Seq_HepG2_Human0.74912972
91MYB_21317192_ChIP-Seq_ERMYB_Mouse0.74516245
92SALL4_18804426_ChIP-ChIP_XEN_Mouse0.73237715
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.72738716
94TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.72653067
95KDM2B_26808549_Chip-Seq_K562_Human0.72593182
96RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.70585162
97EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.70348874
98PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.70248759
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.70175618
100NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.69118405
101WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.69035844
102* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.68418797
103WT1_25993318_ChIP-Seq_PODOCYTE_Human0.68007383
104EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.67888834
105ATF3_27146783_Chip-Seq_COLON_Human0.67739493
106WT1_19549856_ChIP-ChIP_CCG9911_Human0.67642652
107JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.67009251
108KLF4_19829295_ChIP-Seq_ESCs_Human0.66828898
109GATA2_19941826_ChIP-Seq_K562_Human0.66402033
110NR3C1_23031785_ChIP-Seq_PC12_Mouse0.65770385
111KDM2B_26808549_Chip-Seq_SUP-B15_Human0.65484422
112TP53_20018659_ChIP-ChIP_R1E_Mouse0.65369956
113SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.64386666
114LXR_22292898_ChIP-Seq_THP-1_Human0.64131846
115TET1_21490601_ChIP-Seq_MESCs_Mouse0.63671596
116EOMES_21245162_ChIP-Seq_HESCs_Human0.63237350
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.62703574
118GATA4_21415370_ChIP-Seq_HL-1_Mouse0.62513766
119ERG_21242973_ChIP-ChIP_JURKAT_Human0.62005869
120GATA3_24758297_ChIP-Seq_MCF-7_Human0.61704225
121JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.61182107
122RACK7_27058665_Chip-Seq_MCF-7_Human0.60140945
123GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.59824712
124TCF4_18268006_ChIP-ChIP_LS174T_Human0.59722586
125UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.59658297
126ELK4_26923725_Chip-Seq_MESODERM_Mouse0.59494196
127SOX2_27498859_Chip-Seq_STOMACH_Mouse0.59119483
128SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.58617300
129BP1_19119308_ChIP-ChIP_Hs578T_Human0.57811031
130RUNX_20019798_ChIP-Seq_JUKART_Human0.57139314
131SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.56367997
132SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.56367997
133BRD4_25478319_ChIP-Seq_HGPS_Human0.55916217
134SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.55529998

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005670_abnormal_white_adipose8.02833420
2* MP0005666_abnormal_adipose_tissue4.85918971
3* MP0004130_abnormal_muscle_cell4.82055855
4MP0008438_abnormal_cutaneous_collagen3.85146985
5* MP0005375_adipose_tissue_phenotype3.80389507
6* MP0004185_abnormal_adipocyte_glucose3.59153990
7MP0000013_abnormal_adipose_tissue3.53975319
8MP0002971_abnormal_brown_adipose3.31291397
9MP0000003_abnormal_adipose_tissue3.22481393
10MP0002837_dystrophic_cardiac_calcinosis3.12853523
11MP0003011_delayed_dark_adaptation2.74265002
12MP0009115_abnormal_fat_cell2.61164921
13MP0010329_abnormal_lipoprotein_level2.55950177
14MP0005275_abnormal_skin_tensile2.48285445
15MP0003724_increased_susceptibility_to2.39063868
16MP0003191_abnormal_cellular_cholesterol2.35933404
17MP0005334_abnormal_fat_pad2.31250740
18MP0003646_muscle_fatigue2.29630318
19MP0002876_abnormal_thyroid_physiology2.21457702
20MP0005535_abnormal_body_temperature2.00889767
21MP0003705_abnormal_hypodermis_morpholog1.98280422
22MP0005503_abnormal_tendon_morphology1.93266896
23MP0008775_abnormal_heart_ventricle1.92824830
24MP0004272_abnormal_basement_membrane1.91676413
25MP0003828_pulmonary_edema1.90484202
26* MP0002970_abnormal_white_adipose1.88882445
27MP0001661_extended_life_span1.87824177
28* MP0002118_abnormal_lipid_homeostasis1.79970361
29MP0006138_congestive_heart_failure1.62396501
30MP0003186_abnormal_redox_activity1.61355209
31MP0003868_abnormal_feces_composition1.60226230
32MP0003959_abnormal_lean_body1.58092325
33MP0000343_altered_response_to1.51031789
34MP0005448_abnormal_energy_balance1.46254864
35MP0003690_abnormal_glial_cell1.39228082
36MP0001881_abnormal_mammary_gland1.39124102
37MP0002332_abnormal_exercise_endurance1.35539087
38MP0001879_abnormal_lymphatic_vessel1.31615322
39MP0004215_abnormal_myocardial_fiber1.31195382
40MP0001544_abnormal_cardiovascular_syste1.29584920
41MP0005385_cardiovascular_system_phenoty1.29584920
42MP0006036_abnormal_mitochondrial_physio1.29130673
43MP0000751_myopathy1.26204931
44MP0005330_cardiomyopathy1.25689762
45MP0002254_reproductive_system_inflammat1.25241724
46MP0005620_abnormal_muscle_contractility1.25030513
47MP0000750_abnormal_muscle_regeneration1.21055779
48MP0004087_abnormal_muscle_fiber1.20532411
49* MP0005452_abnormal_adipose_tissue1.20219885
50* MP0002078_abnormal_glucose_homeostasis1.19608342
51* MP0000609_abnormal_liver_physiology1.16605252
52MP0003221_abnormal_cardiomyocyte_apopto1.16379733
53MP0003950_abnormal_plasma_membrane1.14825644
54MP0005647_abnormal_sex_gland1.13640343
55MP0001501_abnormal_sleep_pattern1.11521838
56MP0009840_abnormal_foam_cell1.08707253
57MP0003566_abnormal_cell_adhesion1.08670438
58MP0002972_abnormal_cardiac_muscle1.08136140
59MP0008961_abnormal_basal_metabolism1.05413445
60MP0009780_abnormal_chondrocyte_physiolo1.04781370
61MP0003045_fibrosis1.02512668
62MP0002796_impaired_skin_barrier1.01061456
63MP0000759_abnormal_skeletal_muscle1.00253394
64MP0004147_increased_porphyrin_level0.99181264
65MP0005365_abnormal_bile_salt0.99018872
66MP0002909_abnormal_adrenal_gland0.98308203
67MP0002060_abnormal_skin_morphology0.93985759
68MP0005164_abnormal_response_to0.93613697
69MP0004084_abnormal_cardiac_muscle0.92928834
70MP0002166_altered_tumor_susceptibility0.91144399
71MP0004036_abnormal_muscle_relaxation0.89831242
72MP0004782_abnormal_surfactant_physiolog0.89403390
73MP0002933_joint_inflammation0.88473106
74MP0005379_endocrine/exocrine_gland_phen0.86164993
75MP0005584_abnormal_enzyme/coenzyme_acti0.83538845
76MP0001727_abnormal_embryo_implantation0.83242721
77MP0000767_abnormal_smooth_muscle0.82475772
78MP0010630_abnormal_cardiac_muscle0.82067889
79MP0005319_abnormal_enzyme/_coenzyme0.79681553
80MP0003948_abnormal_gas_homeostasis0.75817961
81MP0000604_amyloidosis0.74725149
82MP0010234_abnormal_vibrissa_follicle0.74549524
83MP0000230_abnormal_systemic_arterial0.72444804
84MP0001756_abnormal_urination0.72006033
85MP0002168_other_aberrant_phenotype0.70864059
86MP0000858_altered_metastatic_potential0.70621633
87MP0000249_abnormal_blood_vessel0.69240536
88MP0005332_abnormal_amino_acid0.69219461
89MP0000749_muscle_degeneration0.68278561
90MP0005595_abnormal_vascular_smooth0.67009010
91MP0009643_abnormal_urine_homeostasis0.66573308
92MP0005058_abnormal_lysosome_morphology0.65869946
93MP0004484_altered_response_of0.65520657
94MP0005167_abnormal_blood-brain_barrier0.64717841
95MP0002006_tumorigenesis0.64056526
96MP0003279_aneurysm0.62320502
97MP0002638_abnormal_pupillary_reflex0.62004882
98MP0005360_urolithiasis0.60938035
99MP0009763_increased_sensitivity_to0.60391529
100MP0002106_abnormal_muscle_physiology0.58845052
101MP0001533_abnormal_skeleton_physiology0.58689952
102MP0010368_abnormal_lymphatic_system0.58297489
103MP0005388_respiratory_system_phenotype0.58088379
104MP0002133_abnormal_respiratory_system0.58088379
105MP0003075_altered_response_to0.57418698
106* MP0003953_abnormal_hormone_level0.57063535
107MP0005076_abnormal_cell_differentiation0.56661786
108MP0001958_emphysema0.56509174
109MP0005165_increased_susceptibility_to0.56358771
110MP0004883_abnormal_blood_vessel0.56161868
111MP0002139_abnormal_hepatobiliary_system0.55864390
112MP0002295_abnormal_pulmonary_circulatio0.54845232
113MP0003329_amyloid_beta_deposits0.53960435
114MP0001764_abnormal_homeostasis0.52080915
115MP0002108_abnormal_muscle_morphology0.51350382
116MP0001177_atelectasis0.49914650
117MP0003137_abnormal_impulse_conducting0.49216925
118MP0003448_altered_tumor_morphology0.48587957
119MP0005508_abnormal_skeleton_morphology0.47627078
120MP0005376_homeostasis/metabolism_phenot0.47188314

Predicted human phenotypes

RankGene SetZ-score
1Oligomenorrhea (HP:0000876)7.49678830
2Acanthosis nigricans (HP:0000956)6.27063893
3Hypertriglyceridemia (HP:0002155)5.56382042
4Hyperglycinuria (HP:0003108)5.16915495
5Myoglobinuria (HP:0002913)4.47322649
6Hypoglycemic coma (HP:0001325)4.46202927
7Abnormality of serine family amino acid metabolism (HP:0010894)4.33816677
8Abnormality of glycine metabolism (HP:0010895)4.33816677
9Nausea (HP:0002018)4.25981085
10Insulin-resistant diabetes mellitus (HP:0000831)4.24041665
11Difficulty running (HP:0009046)4.07709901
12Abnormality of fatty-acid metabolism (HP:0004359)4.07580354
13Protrusio acetabuli (HP:0003179)4.02126974
14Complement deficiency (HP:0004431)3.88505786
15Reduced subcutaneous adipose tissue (HP:0003758)3.82040567
16Epidermoid cyst (HP:0200040)3.69721320
17Increased connective tissue (HP:0009025)3.67550034
18Rhabdomyolysis (HP:0003201)3.57864339
19Hydroxyprolinuria (HP:0003080)3.54868091
20Abnormality of proline metabolism (HP:0010907)3.54868091
21Back pain (HP:0003418)3.46857632
22Dicarboxylic aciduria (HP:0003215)3.42564943
23Abnormality of dicarboxylic acid metabolism (HP:0010995)3.42564943
24Bone cyst (HP:0012062)3.39215637
25Ketoacidosis (HP:0001993)3.36080820
26Hypoalphalipoproteinemia (HP:0003233)3.35211734
27Axonal loss (HP:0003447)3.34560025
28Pigmentary retinal degeneration (HP:0001146)3.30016109
29Myocardial infarction (HP:0001658)3.27882308
30Hyperlipoproteinemia (HP:0010980)3.25149302
31Vertebral compression fractures (HP:0002953)3.24403150
32Multiple enchondromatosis (HP:0005701)3.24086750
33Increased muscle lipid content (HP:0009058)3.23327954
34Facial shape deformation (HP:0011334)3.22170961
35Potter facies (HP:0002009)3.22170961
36Insulin resistance (HP:0000855)3.17479286
37Ketosis (HP:0001946)3.11875624
38Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.06835036
39Generalized aminoaciduria (HP:0002909)2.99050831
40Long foot (HP:0001833)2.92228890
41Muscle fiber splitting (HP:0003555)2.88806559
42Growth hormone excess (HP:0000845)2.87691944
43Hemorrhage of the eye (HP:0011885)2.85503318
44Large hands (HP:0001176)2.83835956
45Skin nodule (HP:0200036)2.82442063
46Lipoatrophy (HP:0100578)2.81937297
47Broad metatarsal (HP:0001783)2.81428329
48Cerebral aneurysm (HP:0004944)2.78407938
49Hepatic necrosis (HP:0002605)2.74843508
50Increased variability in muscle fiber diameter (HP:0003557)2.74372792
51Abnormality of complement system (HP:0005339)2.73442033
52Xanthomatosis (HP:0000991)2.70054332
53Hyperammonemia (HP:0001987)2.69913367
54Pulmonary artery stenosis (HP:0004415)2.69522128
55Subcapsular cataract (HP:0000523)2.64627968
56Hyporeflexia of lower limbs (HP:0002600)2.63921364
57Type 1 muscle fiber predominance (HP:0003803)2.60929698
58Toxemia of pregnancy (HP:0100603)2.60116450
59Ankle contracture (HP:0006466)2.59659666
60Frequent falls (HP:0002359)2.58511836
61Hyperglycinemia (HP:0002154)2.58414484
62Abnormal eating behavior (HP:0100738)2.56474397
63Spinal rigidity (HP:0003306)2.56321794
64Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.55904793
65Polycythemia (HP:0001901)2.53577873
66Right ventricular cardiomyopathy (HP:0011663)2.53237528
67Facial diplegia (HP:0001349)2.52099104
68Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.50627644
69Abnormality of alanine metabolism (HP:0010916)2.50627644
70Hyperalaninemia (HP:0003348)2.50627644
71Conjunctival hamartoma (HP:0100780)2.47628556
72Pancreatitis (HP:0001733)2.43142139
73Polyphagia (HP:0002591)2.42969470
74Hypercortisolism (HP:0001578)2.39225432
75Ectopia lentis (HP:0001083)2.35746094
76Abnormality of the periventricular white matter (HP:0002518)2.35420772
77Decreased subcutaneous fat (HP:0001002)2.35408319
78Abnormality of skeletal muscle fiber size (HP:0012084)2.34858826
79Hypercholesterolemia (HP:0003124)2.32869231
80Hepatosplenomegaly (HP:0001433)2.31398587
81Abnormal hemoglobin (HP:0011902)2.30658573
82Ileus (HP:0002595)2.30594804
83Abnormal cartilage morphology (HP:0002763)2.29230027
84Tetraparesis (HP:0002273)2.28869118
85Polar cataract (HP:0010696)2.27776287
86Hyperglycemia (HP:0003074)2.27662323
87Palpitations (HP:0001962)2.27311725
88Muscle stiffness (HP:0003552)2.27261092
89Prenatal maternal abnormality (HP:0002686)2.26350387
90Colitis (HP:0002583)2.25260403
91Polygenic inheritance (HP:0010982)2.19793102
92Exercise-induced myalgia (HP:0003738)2.17769253
93Cerebral edema (HP:0002181)2.16889178
94Neck muscle weakness (HP:0000467)2.15658285
95Systemic lupus erythematosus (HP:0002725)2.13985936
96Vascular tortuosity (HP:0004948)2.11404476
97Renal cortical cysts (HP:0000803)2.10798563
98Follicular hyperkeratosis (HP:0007502)2.10748187
99Increased serum pyruvate (HP:0003542)2.09346402
100Abnormality of glycolysis (HP:0004366)2.09346402
101Hyperpituitarism (HP:0010514)2.06902008
102Acute encephalopathy (HP:0006846)2.05230791
103Cerebral inclusion bodies (HP:0100314)2.05143608
104Infantile muscular hypotonia (HP:0008947)2.04679486
105Amyloidosis (HP:0011034)2.01779822
106Beaking of vertebral bodies (HP:0004568)2.00154262
107Lymphangioma (HP:0100764)1.99918692
108Accelerated skeletal maturation (HP:0005616)1.99687722
109Esophageal varix (HP:0002040)1.99651066
110Prominent supraorbital ridges (HP:0000336)1.96037805
111Abnormal mitochondria in muscle tissue (HP:0008316)1.95268547
112Myotonia (HP:0002486)1.94654007
113Mesangial abnormality (HP:0001966)1.94403652
114Hyperthyroidism (HP:0000836)1.92354926
115Premature rupture of membranes (HP:0001788)1.91474615
116Asymmetric septal hypertrophy (HP:0001670)1.90355339
117Abnormality of subcutaneous fat tissue (HP:0001001)1.89430666
118Gowers sign (HP:0003391)1.88364129
119Tubulointerstitial fibrosis (HP:0005576)1.87849033
120Vomiting (HP:0002013)1.87248779
121Aortic dissection (HP:0002647)1.86332688
122Venous abnormality (HP:0002624)1.85091925
123Abnormality of glycolipid metabolism (HP:0010969)1.84723757
124Abnormality of liposaccharide metabolism (HP:0010968)1.84723757
125Abnormality of glycosphingolipid metabolism (HP:0004343)1.84723757
126Striae distensae (HP:0001065)1.84152357
127Abnormality of serum amino acid levels (HP:0003112)1.83507582
128Proximal tubulopathy (HP:0000114)1.83405152
129Hamartoma of the eye (HP:0010568)1.83016678
130Neoplasm of the adrenal gland (HP:0100631)1.79828956
131Mutism (HP:0002300)1.77976104
132Neonatal death (HP:0003811)1.77940183
133Opisthotonus (HP:0002179)1.77486364
134Thyroid-stimulating hormone excess (HP:0002925)1.77025893
135Abnormality of purine metabolism (HP:0004352)1.76952625
136Lethargy (HP:0001254)1.76951499
137Atrioventricular block (HP:0001678)1.76809269
138Scapular winging (HP:0003691)1.76785678
139Aortic aneurysm (HP:0004942)1.75946577
140Acute necrotizing encephalopathy (HP:0006965)1.75455270
141Dilated cardiomyopathy (HP:0001644)1.75097429
142Increased mean platelet volume (HP:0011877)1.72695706
143Abnormal glucose tolerance (HP:0001952)1.66447755

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CAMK1D5.19053744
2TRIB35.15476582
3BCKDK4.34686378
4SIK13.73548410
5CAMK1G3.68072476
6PDK33.24265599
7PDK43.24265599
8RIPK12.64997511
9ERN12.41892220
10TIE12.38721354
11LMTK22.28216399
12PDK22.22385417
13TESK12.04437368
14CDK92.01888085
15EPHB21.92106567
16MST1R1.86094000
17PRKAA21.82791727
18MAPK41.69098470
19INSRR1.61263743
20TGFBR21.60927592
21TTN1.58287761
22FGFR31.56769751
23PKN21.40402937
24PDGFRA1.33371986
25NLK1.32662678
26PRKD31.30065489
27MAP2K11.25336523
28FGFR21.24299984
29PIK3CA1.21074576
30MYLK1.20618859
31KDR1.13938745
32FRK1.13100094
33JAK11.12798494
34FGFR41.12680520
35LATS11.12591424
36CDC42BPA1.11341187
37PHKG21.09997872
38PHKG11.09997872
39GRK51.08918290
40NME21.00293950
41TEC0.98036595
42RIPK40.93332485
43NEK90.92790208
44CDK60.92512160
45PDPK10.90891881
46MAP3K130.89704394
47ADRBK10.88344823
48PRKAA10.85405059
49KIT0.85013820
50MET0.84682414
51EEF2K0.84573289
52FER0.84186671
53JAK20.81451230
54KSR20.80598973
55PRKCH0.80120360
56PTK20.73269256
57PRPF4B0.71369155
58ZAP700.71201640
59PDK10.70909000
60PRKD10.69414196
61PTK2B0.69168487
62DAPK20.67758629
63PRKG10.67312684
64LATS20.62886696
65ILK0.62757104
66JAK30.62558338
67DDR20.62120108
68MTOR0.61028983
69PINK10.60704322
70IRAK30.60007820
71MAPK30.59762819
72MAP3K60.59158360
73EPHB10.59141715
74MAP2K40.59121017
75OBSCN0.58526387
76IRAK10.57908064
77RET0.56958689
78PRKACG0.56647885
79PDGFRB0.56273261
80GSK3A0.54678763
81PRKACB0.52688067
82PAK40.52535283
83CAMKK10.51127955
84CDK40.50737148
85MAP2K30.50717055
86CAMKK20.50060979
87STK38L0.49207347
88PKN10.48822080
89TGFBR10.48564038
90FLT30.47580307
91EPHA30.47515200
92ABL10.47507535
93MAPK70.47448552
94MAPK110.46857953
95PRKG20.45563413
96MAPKAPK30.45529918
97MAPK120.45290523
98EIF2AK20.45288670
99FES0.45222766
100STK380.44740753
101STK30.44093648
102ARAF0.43148479
103ABL20.42218356
104PTK60.41987602
105SGK20.41820795
106RPS6KA30.41297568
107PIM20.41199567
108PAK20.39449963
109AKT20.38870006
110BLK0.38856553
111MARK20.38117440
112BMX0.36825163
113FGFR10.36637567
114SGK30.36386591
115PRKD20.36155262
116DMPK0.35548425
117CSK0.35065219
118CAMK10.34233662
119* IGF1R0.33364773
120TYRO30.32163219
121TBK10.32001296
122CLK10.31574096
123SCYL20.31546378
124MOS0.31247349
125MAP3K10.30469845
126DAPK30.30355861
127SRC0.30243179
128MAP3K90.30009830
129MAP3K30.29453160
130* INSR0.28845381
131TRPM70.28422531
132TYK20.28168821
133RPS6KB10.25264975
134IRAK20.25159524

Predicted pathways (KEGG)

RankGene SetZ-score
1Propanoate metabolism_Homo sapiens_hsa006404.92783390
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.66364624
3* PPAR signaling pathway_Homo sapiens_hsa033204.27782094
4Fatty acid biosynthesis_Homo sapiens_hsa000613.97603907
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.81181089
6* Regulation of lipolysis in adipocytes_Homo sapiens_hsa049233.55561948
7Fatty acid metabolism_Homo sapiens_hsa012123.44099592
8Fatty acid degradation_Homo sapiens_hsa000713.15861582
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.94488632
10Glycerolipid metabolism_Homo sapiens_hsa005612.66115799
11Pyruvate metabolism_Homo sapiens_hsa006202.30541078
12Adipocytokine signaling pathway_Homo sapiens_hsa049202.22127942
13Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.08927818
14Carbon metabolism_Homo sapiens_hsa012002.03324226
15Caffeine metabolism_Homo sapiens_hsa002321.92358430
16AMPK signaling pathway_Homo sapiens_hsa041521.90648560
17beta-Alanine metabolism_Homo sapiens_hsa004101.88853065
18Histidine metabolism_Homo sapiens_hsa003401.66170921
19Peroxisome_Homo sapiens_hsa041461.55660148
20Fat digestion and absorption_Homo sapiens_hsa049751.54269775
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.43134007
22Fatty acid elongation_Homo sapiens_hsa000621.41256563
23Nitrogen metabolism_Homo sapiens_hsa009101.36381429
24Butanoate metabolism_Homo sapiens_hsa006501.31986999
25Insulin resistance_Homo sapiens_hsa049311.31753279
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.15565088
27Insulin signaling pathway_Homo sapiens_hsa049101.11855011
28Staphylococcus aureus infection_Homo sapiens_hsa051501.11790888
29Phenylalanine metabolism_Homo sapiens_hsa003601.05037621
30Longevity regulating pathway - mammal_Homo sapiens_hsa042111.02613118
31Vitamin B6 metabolism_Homo sapiens_hsa007500.92896983
32Renin-angiotensin system_Homo sapiens_hsa046140.91575277
33Glucagon signaling pathway_Homo sapiens_hsa049220.90433646
34Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89977939
35Tryptophan metabolism_Homo sapiens_hsa003800.88257184
36Tyrosine metabolism_Homo sapiens_hsa003500.86624710
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.81734093
38ECM-receptor interaction_Homo sapiens_hsa045120.77596638
39Parkinsons disease_Homo sapiens_hsa050120.71100182
40Glycerophospholipid metabolism_Homo sapiens_hsa005640.68495659
41Renin secretion_Homo sapiens_hsa049240.68424362
42Sulfur metabolism_Homo sapiens_hsa009200.68063900
43Steroid biosynthesis_Homo sapiens_hsa001000.67457231
44Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65753800
45Alzheimers disease_Homo sapiens_hsa050100.63826499
46Oxidative phosphorylation_Homo sapiens_hsa001900.62614519
47Pentose phosphate pathway_Homo sapiens_hsa000300.61930793
48Type II diabetes mellitus_Homo sapiens_hsa049300.59625751
49Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55635185
50Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55541288
51Glycosaminoglycan degradation_Homo sapiens_hsa005310.55220449
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.55046415
53Retinol metabolism_Homo sapiens_hsa008300.54728734
54Focal adhesion_Homo sapiens_hsa045100.52680884
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51154339
56Starch and sucrose metabolism_Homo sapiens_hsa005000.48792578
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48748372
58HIF-1 signaling pathway_Homo sapiens_hsa040660.45454776
59Protein digestion and absorption_Homo sapiens_hsa049740.44855494
60Biosynthesis of amino acids_Homo sapiens_hsa012300.43004682
61Complement and coagulation cascades_Homo sapiens_hsa046100.41990412
62Viral myocarditis_Homo sapiens_hsa054160.41322317
63Huntingtons disease_Homo sapiens_hsa050160.39620297
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.39125902
65ABC transporters_Homo sapiens_hsa020100.37966923
66Lysine degradation_Homo sapiens_hsa003100.37853991
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34579651
68Folate biosynthesis_Homo sapiens_hsa007900.34387258
69Other glycan degradation_Homo sapiens_hsa005110.34259556
70Thyroid cancer_Homo sapiens_hsa052160.33706957
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.32895438
72Arginine biosynthesis_Homo sapiens_hsa002200.32112373
73Cardiac muscle contraction_Homo sapiens_hsa042600.31941117
74Proteoglycans in cancer_Homo sapiens_hsa052050.30499867
75Dilated cardiomyopathy_Homo sapiens_hsa054140.30409109
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.29805280
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.29321183
78Small cell lung cancer_Homo sapiens_hsa052220.29265343
79Acute myeloid leukemia_Homo sapiens_hsa052210.28645606
80Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.27598041
81mTOR signaling pathway_Homo sapiens_hsa041500.27571694
82cAMP signaling pathway_Homo sapiens_hsa040240.26590937
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25740410
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.25462454
85Amoebiasis_Homo sapiens_hsa051460.25005930
86Toxoplasmosis_Homo sapiens_hsa051450.24793846
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.24692964
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24412522
89Malaria_Homo sapiens_hsa051440.23143453
90Arginine and proline metabolism_Homo sapiens_hsa003300.22461486
91Vitamin digestion and absorption_Homo sapiens_hsa049770.21817440
92Melanoma_Homo sapiens_hsa052180.21807027
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.21540770
94Fructose and mannose metabolism_Homo sapiens_hsa000510.21024318
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.20406319
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.20180358
97Glutathione metabolism_Homo sapiens_hsa004800.19770716
98Linoleic acid metabolism_Homo sapiens_hsa005910.18908960
99Metabolic pathways_Homo sapiens_hsa011000.18084870
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.18009969
101Sulfur relay system_Homo sapiens_hsa041220.17858608
102Arachidonic acid metabolism_Homo sapiens_hsa005900.17110140
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16833485
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.16375023
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.15982730
106Jak-STAT signaling pathway_Homo sapiens_hsa046300.15632797
107Lysosome_Homo sapiens_hsa041420.14035086
108Pentose and glucuronate interconversions_Homo sapiens_hsa000400.12663152
109Adherens junction_Homo sapiens_hsa045200.11510187
110FoxO signaling pathway_Homo sapiens_hsa040680.11331307
111Ovarian steroidogenesis_Homo sapiens_hsa049130.10626000
112Steroid hormone biosynthesis_Homo sapiens_hsa001400.10598931
113Autoimmune thyroid disease_Homo sapiens_hsa053200.08734117
114Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.08169217
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.07656178
116Osteoclast differentiation_Homo sapiens_hsa043800.07644244
117Phagosome_Homo sapiens_hsa041450.07529399
118Chemical carcinogenesis_Homo sapiens_hsa052040.06825581
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.06736267
120Mineral absorption_Homo sapiens_hsa049780.03175271
121Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.02664041
122Pertussis_Homo sapiens_hsa051330.00356479
123Circadian rhythm_Homo sapiens_hsa04710-0.0071346

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