

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.57602993 |
| 2 | maturation of 5.8S rRNA (GO:0000460) | 5.29104692 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.97365776 |
| 4 | cytidine metabolic process (GO:0046087) | 4.85350693 |
| 5 | cytidine catabolic process (GO:0006216) | 4.85350693 |
| 6 | cytidine deamination (GO:0009972) | 4.85350693 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.55499508 |
| 8 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.55499508 |
| 9 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.50777506 |
| 10 | proteasome assembly (GO:0043248) | 4.44862554 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.44735401 |
| 12 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.41329704 |
| 13 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.41329704 |
| 14 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.41156020 |
| 15 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.41156020 |
| 16 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.41156020 |
| 17 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.40222638 |
| 18 | GTP biosynthetic process (GO:0006183) | 4.31532512 |
| 19 | maturation of SSU-rRNA (GO:0030490) | 4.30175943 |
| 20 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 4.24815399 |
| 21 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 4.24815399 |
| 22 | isotype switching (GO:0045190) | 4.24815399 |
| 23 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.24271691 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.23667744 |
| 25 | ATP synthesis coupled proton transport (GO:0015986) | 4.23667744 |
| 26 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.23256772 |
| 27 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.23256772 |
| 28 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.18895318 |
| 29 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.17091031 |
| 30 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.04285119 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.98113703 |
| 32 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.96336146 |
| 33 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.95908779 |
| 34 | negative regulation of ligase activity (GO:0051352) | 3.95908779 |
| 35 | cellular response to ATP (GO:0071318) | 3.94837662 |
| 36 | chaperone-mediated protein transport (GO:0072321) | 3.94559544 |
| 37 | UTP biosynthetic process (GO:0006228) | 3.83076496 |
| 38 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.82948146 |
| 39 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.80092601 |
| 40 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.80092601 |
| 41 | NADH dehydrogenase complex assembly (GO:0010257) | 3.80092601 |
| 42 | protein complex biogenesis (GO:0070271) | 3.77014158 |
| 43 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.67286776 |
| 44 | ribosomal large subunit biogenesis (GO:0042273) | 3.66832777 |
| 45 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.65300872 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.57567452 |
| 47 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.56226842 |
| 48 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.55133975 |
| 49 | protein K63-linked deubiquitination (GO:0070536) | 3.50707422 |
| 50 | positive regulation of ligase activity (GO:0051351) | 3.45330764 |
| 51 | UTP metabolic process (GO:0046051) | 3.44244819 |
| 52 | positive regulation of cell cycle arrest (GO:0071158) | 3.44197140 |
| 53 | viral mRNA export from host cell nucleus (GO:0046784) | 3.43612583 |
| 54 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.43407887 |
| 55 | glomerular visceral epithelial cell development (GO:0072015) | 3.42758135 |
| 56 | electron transport chain (GO:0022900) | 3.40508569 |
| 57 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.40061186 |
| 58 | respiratory electron transport chain (GO:0022904) | 3.37641009 |
| 59 | histone mRNA metabolic process (GO:0008334) | 3.37132949 |
| 60 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.34188549 |
| 61 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.32134572 |
| 62 | rRNA modification (GO:0000154) | 3.30421469 |
| 63 | protein neddylation (GO:0045116) | 3.24804138 |
| 64 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.23979758 |
| 65 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 3.23689072 |
| 66 | GDP-mannose metabolic process (GO:0019673) | 3.23570664 |
| 67 | rRNA methylation (GO:0031167) | 3.22003938 |
| 68 | rRNA processing (GO:0006364) | 3.17858680 |
| 69 | regulation of cellular amine metabolic process (GO:0033238) | 3.17787949 |
| 70 | pseudouridine synthesis (GO:0001522) | 3.13772862 |
| 71 | rRNA metabolic process (GO:0016072) | 3.06390869 |
| 72 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.03370573 |
| 73 | ncRNA catabolic process (GO:0034661) | 3.01637027 |
| 74 | CTP metabolic process (GO:0046036) | 3.00893142 |
| 75 | CTP biosynthetic process (GO:0006241) | 3.00893142 |
| 76 | glomerular epithelial cell development (GO:0072310) | 2.97017246 |
| 77 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.95818004 |
| 78 | DNA replication checkpoint (GO:0000076) | 2.93361954 |
| 79 | DNA double-strand break processing (GO:0000729) | 2.92779102 |
| 80 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.91260128 |
| 81 | regulation of ligase activity (GO:0051340) | 2.90252468 |
| 82 | signal peptide processing (GO:0006465) | 2.90022034 |
| 83 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.89761848 |
| 84 | sequestering of metal ion (GO:0051238) | 2.87179296 |
| 85 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85049491 |
| 86 | regulation of immunoglobulin secretion (GO:0051023) | 2.84004554 |
| 87 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.83298206 |
| 88 | IMP biosynthetic process (GO:0006188) | 2.81974740 |
| 89 | negative regulation of protein ubiquitination (GO:0031397) | 2.81273910 |
| 90 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.79735262 |
| 91 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.79735262 |
| 92 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.79422926 |
| 93 | termination of RNA polymerase III transcription (GO:0006386) | 2.79422926 |
| 94 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.79411699 |
| 95 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.79411699 |
| 96 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.77326123 |
| 97 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.76952605 |
| 98 | signal transduction in response to DNA damage (GO:0042770) | 2.76304353 |
| 99 | regulation of cell cycle arrest (GO:0071156) | 2.76266609 |
| 100 | aldehyde catabolic process (GO:0046185) | 2.75688628 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.28041145 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.00425970 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.61113565 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.90044808 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.57813477 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.43599324 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.32767840 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.03402230 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.82543482 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79005010 |
| 11 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.63060864 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.48709660 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.47896363 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.46831667 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.44775918 |
| 16 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.36670067 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.35360655 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26439545 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.19476617 |
| 20 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.17577049 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12057626 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.11797426 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.00144262 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.93010373 |
| 25 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.91287509 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.86323746 |
| 27 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.82908489 |
| 28 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.77094330 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.75780939 |
| 30 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.72140159 |
| 31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.68648847 |
| 32 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.65639501 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.63175969 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.60794373 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.58293790 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57519999 |
| 37 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.53341134 |
| 38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.51879487 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.50715178 |
| 40 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.50597954 |
| 41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.47838905 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.47244404 |
| 43 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.44851432 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41673412 |
| 45 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.41003670 |
| 46 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.39650484 |
| 47 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.39125832 |
| 48 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38886693 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.37021222 |
| 50 | EWS_26573619_Chip-Seq_HEK293_Human | 1.36030589 |
| 51 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.34465356 |
| 52 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.32345501 |
| 53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.31633196 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.30194094 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.27337425 |
| 56 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26751265 |
| 57 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.26544821 |
| 58 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.20993693 |
| 59 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.17711562 |
| 60 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16132120 |
| 61 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15162667 |
| 62 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12897467 |
| 63 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11995548 |
| 64 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07715327 |
| 65 | GATA3_26560356_Chip-Seq_TH2_Human | 1.04029477 |
| 66 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.02899013 |
| 67 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.02094666 |
| 68 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.00467274 |
| 69 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.00207954 |
| 70 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98824708 |
| 71 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.98440310 |
| 72 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98327848 |
| 73 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.98279138 |
| 74 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94916840 |
| 75 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94916840 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.94259308 |
| 77 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.94259308 |
| 78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.94014711 |
| 79 | P300_19829295_ChIP-Seq_ESCs_Human | 0.93757088 |
| 80 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.93139545 |
| 81 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92376462 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91974704 |
| 83 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.91623748 |
| 84 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91201867 |
| 85 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90964871 |
| 86 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.87169324 |
| 87 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.86811313 |
| 88 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.86074662 |
| 89 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.84929299 |
| 90 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.84831780 |
| 91 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.84203318 |
| 92 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.84034470 |
| 93 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.83949396 |
| 94 | AR_20517297_ChIP-Seq_VCAP_Human | 0.83715560 |
| 95 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.83654594 |
| 96 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.82574123 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.82406474 |
| 98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.81793935 |
| 99 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.81132038 |
| 100 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.80180594 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.09245275 |
| 2 | MP0005671_abnormal_response_to | 3.99959754 |
| 3 | MP0008875_abnormal_xenobiotic_pharmacok | 3.96480980 |
| 4 | MP0002102_abnormal_ear_morphology | 3.44941776 |
| 5 | MP0003806_abnormal_nucleotide_metabolis | 3.30806080 |
| 6 | MP0003693_abnormal_embryo_hatching | 3.18029267 |
| 7 | MP0003195_calcinosis | 2.94546486 |
| 8 | MP0000685_abnormal_immune_system | 2.78095855 |
| 9 | MP0001873_stomach_inflammation | 2.75029157 |
| 10 | MP0005408_hypopigmentation | 2.55826741 |
| 11 | MP0008058_abnormal_DNA_repair | 2.55300797 |
| 12 | MP0002736_abnormal_nociception_after | 2.43345378 |
| 13 | MP0005360_urolithiasis | 2.37931262 |
| 14 | MP0003950_abnormal_plasma_membrane | 2.15216385 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.14053602 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 2.13612187 |
| 17 | MP0009785_altered_susceptibility_to | 2.08505154 |
| 18 | MP0008872_abnormal_physiological_respon | 2.06352084 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 2.04382444 |
| 20 | MP0001790_abnormal_immune_system | 2.03412531 |
| 21 | MP0005387_immune_system_phenotype | 2.03412531 |
| 22 | MP0004957_abnormal_blastocyst_morpholog | 2.03096095 |
| 23 | MP0003890_abnormal_embryonic-extraembry | 1.91103099 |
| 24 | MP0005084_abnormal_gallbladder_morpholo | 1.84187190 |
| 25 | MP0004147_increased_porphyrin_level | 1.81345378 |
| 26 | MP0001529_abnormal_vocalization | 1.78498453 |
| 27 | MP0005167_abnormal_blood-brain_barrier | 1.77015710 |
| 28 | MP0010094_abnormal_chromosome_stability | 1.73229392 |
| 29 | MP0003045_fibrosis | 1.67480895 |
| 30 | MP0001800_abnormal_humoral_immune | 1.59813015 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.51517494 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.51389305 |
| 33 | MP0004142_abnormal_muscle_tone | 1.50276598 |
| 34 | MP0003786_premature_aging | 1.46089245 |
| 35 | MP0006036_abnormal_mitochondrial_physio | 1.44051829 |
| 36 | MP0002148_abnormal_hypersensitivity_rea | 1.34869984 |
| 37 | MP0008007_abnormal_cellular_replicative | 1.31973340 |
| 38 | MP0005000_abnormal_immune_tolerance | 1.31806603 |
| 39 | MP0003186_abnormal_redox_activity | 1.26781648 |
| 40 | MP0004885_abnormal_endolymph | 1.24275382 |
| 41 | MP0004782_abnormal_surfactant_physiolog | 1.24073913 |
| 42 | MP0003011_delayed_dark_adaptation | 1.18880507 |
| 43 | MP0008877_abnormal_DNA_methylation | 1.18073847 |
| 44 | MP0002405_respiratory_system_inflammati | 1.17476310 |
| 45 | MP0002006_tumorigenesis | 1.15285498 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 1.15139151 |
| 47 | MP0003718_maternal_effect | 1.14990252 |
| 48 | MP0002138_abnormal_hepatobiliary_system | 1.12692218 |
| 49 | MP0000749_muscle_degeneration | 1.11893820 |
| 50 | MP0005636_abnormal_mineral_homeostasis | 1.11755378 |
| 51 | MP0010155_abnormal_intestine_physiology | 1.09533447 |
| 52 | MP0001919_abnormal_reproductive_system | 1.08309140 |
| 53 | MP0002452_abnormal_antigen_presenting | 1.04365923 |
| 54 | MP0000372_irregular_coat_pigmentation | 0.98751498 |
| 55 | MP0001905_abnormal_dopamine_level | 0.97208414 |
| 56 | MP0005389_reproductive_system_phenotype | 0.96926288 |
| 57 | MP0001764_abnormal_homeostasis | 0.96799266 |
| 58 | MP0003866_abnormal_defecation | 0.95313514 |
| 59 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94606440 |
| 60 | MP0006035_abnormal_mitochondrial_morpho | 0.94211469 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 0.92931284 |
| 62 | MP0003763_abnormal_thymus_physiology | 0.92455949 |
| 63 | MP0002723_abnormal_immune_serum | 0.92335898 |
| 64 | MP0005025_abnormal_response_to | 0.91069589 |
| 65 | MP0005085_abnormal_gallbladder_physiolo | 0.89566788 |
| 66 | MP0002909_abnormal_adrenal_gland | 0.89438073 |
| 67 | MP0001958_emphysema | 0.89412482 |
| 68 | MP0008873_increased_physiological_sensi | 0.87280268 |
| 69 | MP0003137_abnormal_impulse_conducting | 0.86426317 |
| 70 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.85746864 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.84387773 |
| 72 | MP0005365_abnormal_bile_salt | 0.83902948 |
| 73 | MP0002420_abnormal_adaptive_immunity | 0.83588820 |
| 74 | MP0005379_endocrine/exocrine_gland_phen | 0.82531891 |
| 75 | MP0001845_abnormal_inflammatory_respons | 0.82097083 |
| 76 | MP0001819_abnormal_immune_cell | 0.81309546 |
| 77 | MP0005319_abnormal_enzyme/_coenzyme | 0.79795610 |
| 78 | MP0000470_abnormal_stomach_morphology | 0.79593420 |
| 79 | MP0009745_abnormal_behavioral_response | 0.79110126 |
| 80 | MP0000358_abnormal_cell_content/ | 0.78808882 |
| 81 | MP0000689_abnormal_spleen_morphology | 0.78691784 |
| 82 | MP0005075_abnormal_melanosome_morpholog | 0.76687817 |
| 83 | MP0005076_abnormal_cell_differentiation | 0.76045598 |
| 84 | MP0005332_abnormal_amino_acid | 0.75870726 |
| 85 | MP0001485_abnormal_pinna_reflex | 0.74249194 |
| 86 | MP0003111_abnormal_nucleus_morphology | 0.69855380 |
| 87 | MP0003646_muscle_fatigue | 0.68655843 |
| 88 | MP0003252_abnormal_bile_duct | 0.68095674 |
| 89 | MP0002938_white_spotting | 0.67275395 |
| 90 | MP0004742_abnormal_vestibular_system | 0.64369343 |
| 91 | MP0002733_abnormal_thermal_nociception | 0.64308398 |
| 92 | MP0003943_abnormal_hepatobiliary_system | 0.63359901 |
| 93 | MP0002139_abnormal_hepatobiliary_system | 0.63191917 |
| 94 | MP0001663_abnormal_digestive_system | 0.63099857 |
| 95 | MP0004019_abnormal_vitamin_homeostasis | 0.62602263 |
| 96 | MP0002396_abnormal_hematopoietic_system | 0.62558291 |
| 97 | MP0001970_abnormal_pain_threshold | 0.60168733 |
| 98 | MP0003638_abnormal_response/metabolism_ | 0.58449033 |
| 99 | MP0003077_abnormal_cell_cycle | 0.57560809 |
| 100 | MP0000716_abnormal_immune_system | 0.57536228 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.10564565 |
| 2 | Hypoproteinemia (HP:0003075) | 5.56513389 |
| 3 | Abnormality of the pons (HP:0007361) | 4.92749686 |
| 4 | Reduced antithrombin III activity (HP:0001976) | 4.89628260 |
| 5 | Hypoplasia of the pons (HP:0012110) | 4.38811377 |
| 6 | Type I transferrin isoform profile (HP:0003642) | 4.21899728 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 4.16045087 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.92647144 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.78627119 |
| 10 | Abnormality of DNA repair (HP:0003254) | 3.70651947 |
| 11 | Increased CSF lactate (HP:0002490) | 3.60080323 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.50186977 |
| 13 | Hepatic necrosis (HP:0002605) | 3.47588678 |
| 14 | Acute encephalopathy (HP:0006846) | 3.45922458 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.33444303 |
| 16 | Increased IgM level (HP:0003496) | 3.31452927 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.29589912 |
| 18 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.29589912 |
| 19 | Increased serum pyruvate (HP:0003542) | 3.24075190 |
| 20 | Duplicated collecting system (HP:0000081) | 3.21854290 |
| 21 | Type 2 muscle fiber atrophy (HP:0003554) | 3.20867909 |
| 22 | IgG deficiency (HP:0004315) | 3.16428939 |
| 23 | Cerebral hypomyelination (HP:0006808) | 3.12194070 |
| 24 | Abnormal protein glycosylation (HP:0012346) | 3.02341563 |
| 25 | Abnormal glycosylation (HP:0012345) | 3.02341563 |
| 26 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.02341563 |
| 27 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.02341563 |
| 28 | CNS demyelination (HP:0007305) | 2.98474484 |
| 29 | Abnormality of placental membranes (HP:0011409) | 2.84305729 |
| 30 | Amniotic constriction ring (HP:0009775) | 2.84305729 |
| 31 | Abnormality of the renal collecting system (HP:0004742) | 2.83129093 |
| 32 | Increased serum lactate (HP:0002151) | 2.74644552 |
| 33 | Abnormality of glycolysis (HP:0004366) | 2.69316168 |
| 34 | Muscle fiber atrophy (HP:0100295) | 2.65812545 |
| 35 | Methylmalonic acidemia (HP:0002912) | 2.64926439 |
| 36 | Oral leukoplakia (HP:0002745) | 2.64334585 |
| 37 | Increased hepatocellular lipid droplets (HP:0006565) | 2.62287667 |
| 38 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.59805112 |
| 39 | Exercise intolerance (HP:0003546) | 2.56095192 |
| 40 | Lipid accumulation in hepatocytes (HP:0006561) | 2.53661886 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.51450775 |
| 42 | Abnormality of methionine metabolism (HP:0010901) | 2.50716495 |
| 43 | Poor head control (HP:0002421) | 2.50602104 |
| 44 | Cerebral edema (HP:0002181) | 2.49306811 |
| 45 | Abnormality of T cell physiology (HP:0011840) | 2.45067733 |
| 46 | Abnormality of the ileum (HP:0001549) | 2.37408304 |
| 47 | Panhypogammaglobulinemia (HP:0003139) | 2.36916296 |
| 48 | Optic disc pallor (HP:0000543) | 2.34202790 |
| 49 | Respiratory failure (HP:0002878) | 2.32858353 |
| 50 | Hypochromic microcytic anemia (HP:0004840) | 2.30137884 |
| 51 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.29932590 |
| 52 | Absent/shortened dynein arms (HP:0200106) | 2.29932590 |
| 53 | IgA deficiency (HP:0002720) | 2.25229888 |
| 54 | Absent thumb (HP:0009777) | 2.24524521 |
| 55 | Large for gestational age (HP:0001520) | 2.24319985 |
| 56 | Lactic acidosis (HP:0003128) | 2.22155747 |
| 57 | Abnormality of the labia minora (HP:0012880) | 2.20454392 |
| 58 | Increased intramyocellular lipid droplets (HP:0012240) | 2.19419147 |
| 59 | Cleft eyelid (HP:0000625) | 2.16812974 |
| 60 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.16703826 |
| 61 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.15280978 |
| 62 | Multiple enchondromatosis (HP:0005701) | 2.10082306 |
| 63 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.09672006 |
| 64 | Lethargy (HP:0001254) | 2.09102949 |
| 65 | Prolonged QT interval (HP:0001657) | 2.08751960 |
| 66 | Abnormality of the prostate (HP:0008775) | 2.06909623 |
| 67 | Oligomenorrhea (HP:0000876) | 2.06611539 |
| 68 | Abnormality of the renal cortex (HP:0011035) | 2.04802576 |
| 69 | Renal cortical cysts (HP:0000803) | 2.04463187 |
| 70 | Leukodystrophy (HP:0002415) | 2.01256198 |
| 71 | Exertional dyspnea (HP:0002875) | 2.00694012 |
| 72 | Meckel diverticulum (HP:0002245) | 1.99000766 |
| 73 | Opisthotonus (HP:0002179) | 1.96317379 |
| 74 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92390438 |
| 75 | Clubbing of toes (HP:0100760) | 1.91196831 |
| 76 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.90923795 |
| 77 | Renal Fanconi syndrome (HP:0001994) | 1.90551006 |
| 78 | Abnormality of the preputium (HP:0100587) | 1.89908110 |
| 79 | Abnormality of the anterior horn cell (HP:0006802) | 1.87128193 |
| 80 | Degeneration of anterior horn cells (HP:0002398) | 1.87128193 |
| 81 | Generalized aminoaciduria (HP:0002909) | 1.85579934 |
| 82 | Abnormality of T cells (HP:0002843) | 1.85378634 |
| 83 | Microvesicular hepatic steatosis (HP:0001414) | 1.84469488 |
| 84 | Inability to walk (HP:0002540) | 1.83124597 |
| 85 | Increased muscle lipid content (HP:0009058) | 1.80783226 |
| 86 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.77694201 |
| 87 | Myopathic facies (HP:0002058) | 1.77518841 |
| 88 | Respiratory difficulties (HP:0002880) | 1.69380973 |
| 89 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.69136058 |
| 90 | Dicarboxylic aciduria (HP:0003215) | 1.69136058 |
| 91 | Supernumerary spleens (HP:0009799) | 1.68535584 |
| 92 | Abnormality of alanine metabolism (HP:0010916) | 1.67746078 |
| 93 | Hyperalaninemia (HP:0003348) | 1.67746078 |
| 94 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.67746078 |
| 95 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.67457548 |
| 96 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.67457548 |
| 97 | Homocystinuria (HP:0002156) | 1.65828206 |
| 98 | Abnormality of homocysteine metabolism (HP:0010919) | 1.65828206 |
| 99 | Megaloblastic anemia (HP:0001889) | 1.65767203 |
| 100 | Cerebral hemorrhage (HP:0001342) | 1.63826336 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.11726346 |
| 2 | EIF2AK3 | 4.03935025 |
| 3 | TLK1 | 3.37850644 |
| 4 | MST4 | 3.32494613 |
| 5 | NUAK1 | 3.23018718 |
| 6 | BUB1 | 3.20425713 |
| 7 | ZAK | 3.05378069 |
| 8 | VRK1 | 2.76341235 |
| 9 | TSSK6 | 2.55579261 |
| 10 | EIF2AK1 | 2.48366118 |
| 11 | NME1 | 2.36969009 |
| 12 | TXK | 2.36569064 |
| 13 | TAF1 | 2.21034547 |
| 14 | MAP3K12 | 2.13634365 |
| 15 | ADRBK2 | 1.90249882 |
| 16 | NEK1 | 1.90099538 |
| 17 | PLK3 | 1.83685715 |
| 18 | PBK | 1.82358003 |
| 19 | SMG1 | 1.81052875 |
| 20 | IKBKE | 1.46741914 |
| 21 | NEK9 | 1.44762516 |
| 22 | GRK1 | 1.41670151 |
| 23 | DAPK1 | 1.36346219 |
| 24 | WNK3 | 1.27359551 |
| 25 | PDK2 | 1.27172476 |
| 26 | CCNB1 | 1.24577157 |
| 27 | EIF2AK2 | 1.20801753 |
| 28 | SCYL2 | 1.19525139 |
| 29 | PLK4 | 1.18083160 |
| 30 | TRIM28 | 1.15801020 |
| 31 | OXSR1 | 1.13177655 |
| 32 | IKBKB | 1.09337430 |
| 33 | DYRK2 | 1.08029521 |
| 34 | CSNK1G3 | 1.06746813 |
| 35 | PLK2 | 1.06553051 |
| 36 | WEE1 | 1.05092431 |
| 37 | CSNK1A1L | 1.03072482 |
| 38 | MYLK | 1.01940973 |
| 39 | NME2 | 0.97386581 |
| 40 | FRK | 0.97201364 |
| 41 | CAMKK2 | 0.96099016 |
| 42 | OBSCN | 0.93188258 |
| 43 | ATR | 0.91941687 |
| 44 | BCKDK | 0.88052535 |
| 45 | BMPR1B | 0.86066799 |
| 46 | DAPK2 | 0.84015626 |
| 47 | CSNK1G1 | 0.83203660 |
| 48 | PAK4 | 0.83177385 |
| 49 | CSNK1G2 | 0.83156603 |
| 50 | DAPK3 | 0.82954184 |
| 51 | SYK | 0.79481475 |
| 52 | STK16 | 0.77454104 |
| 53 | PLK1 | 0.76119657 |
| 54 | FGFR1 | 0.75825258 |
| 55 | PRKCQ | 0.73933115 |
| 56 | JAK3 | 0.72593380 |
| 57 | TAOK3 | 0.71406925 |
| 58 | SRPK1 | 0.68537646 |
| 59 | STK39 | 0.64090643 |
| 60 | CDC7 | 0.61499688 |
| 61 | AURKB | 0.60362597 |
| 62 | INSRR | 0.60201303 |
| 63 | RIPK4 | 0.60075057 |
| 64 | WNK4 | 0.59069086 |
| 65 | PHKG1 | 0.58971554 |
| 66 | PHKG2 | 0.58971554 |
| 67 | TTK | 0.56364322 |
| 68 | AURKA | 0.56170845 |
| 69 | STK10 | 0.55018559 |
| 70 | STK4 | 0.54519476 |
| 71 | PNCK | 0.53119525 |
| 72 | LATS1 | 0.49810946 |
| 73 | PRKCE | 0.47322773 |
| 74 | TIE1 | 0.46028098 |
| 75 | ADRBK1 | 0.45592838 |
| 76 | IGF1R | 0.45457208 |
| 77 | CHEK2 | 0.45416652 |
| 78 | RPS6KA5 | 0.44486848 |
| 79 | ATM | 0.44324579 |
| 80 | MAPKAPK5 | 0.43425708 |
| 81 | GRK5 | 0.41194442 |
| 82 | MKNK2 | 0.41159132 |
| 83 | LYN | 0.41036079 |
| 84 | CSNK2A2 | 0.39735405 |
| 85 | ITK | 0.39540788 |
| 86 | PRKCG | 0.38058142 |
| 87 | CSNK1E | 0.37256382 |
| 88 | PRKDC | 0.36827868 |
| 89 | PRKCA | 0.35460024 |
| 90 | CSNK1A1 | 0.34531216 |
| 91 | ALK | 0.33648011 |
| 92 | GRK7 | 0.32228073 |
| 93 | MAP3K14 | 0.31012589 |
| 94 | LCK | 0.29830285 |
| 95 | PRKCD | 0.29623233 |
| 96 | CSNK2A1 | 0.29003940 |
| 97 | PRKACA | 0.28244515 |
| 98 | PINK1 | 0.27168528 |
| 99 | MINK1 | 0.25465804 |
| 100 | CHEK1 | 0.25191708 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.57660890 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.13125318 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.84251954 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.73665223 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.67184295 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.47975453 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.45974499 |
| 8 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.31849749 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.16857937 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.10583131 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.92628227 |
| 12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.85909319 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.79347850 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.74882541 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.74443053 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.72187780 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.71635405 |
| 18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.71007223 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.66218284 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.62699487 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.60996823 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58761202 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.56195272 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.54970519 |
| 25 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.54592997 |
| 26 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.50172599 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.45667122 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.42863552 |
| 29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.41327193 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34760159 |
| 31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32424713 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28074943 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23412676 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.12015065 |
| 35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.07210288 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.04003766 |
| 37 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.03903386 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.03682255 |
| 39 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.03544633 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.03417432 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.03259802 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03134455 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02765890 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.01984948 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.01585117 |
| 46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.01177122 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.96005877 |
| 48 | Spliceosome_Homo sapiens_hsa03040 | 0.94864505 |
| 49 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91189122 |
| 50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90066379 |
| 51 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.88344431 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 0.87889524 |
| 53 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.82792129 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.79369083 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.79349283 |
| 56 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.78503498 |
| 57 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.78439084 |
| 58 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.75594415 |
| 59 | Histidine metabolism_Homo sapiens_hsa00340 | 0.73357964 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.73184725 |
| 61 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72169455 |
| 62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.69149845 |
| 63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.69028134 |
| 64 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.62957057 |
| 65 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62238676 |
| 66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.61230406 |
| 67 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.61104122 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.58577337 |
| 69 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.57590157 |
| 70 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.55906724 |
| 71 | Carbon metabolism_Homo sapiens_hsa01200 | 0.55100896 |
| 72 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.54608883 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53915261 |
| 74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.53814380 |
| 75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.51471020 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49914620 |
| 77 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.49329588 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.46964954 |
| 79 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.45109853 |
| 80 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.44336911 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.44150741 |
| 82 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41362460 |
| 83 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.40679506 |
| 84 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40103791 |
| 85 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.37735762 |
| 86 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.37576899 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.36763682 |
| 88 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36068301 |
| 89 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35408950 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34233690 |
| 91 | Phototransduction_Homo sapiens_hsa04744 | 0.34009148 |
| 92 | Alcoholism_Homo sapiens_hsa05034 | 0.32150166 |
| 93 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31184899 |
| 94 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.30101398 |
| 95 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.30076127 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29871877 |
| 97 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.27755025 |
| 98 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.27231368 |
| 99 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.26234965 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.26089197 |

