FABP7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of vascular permeability (GO:0043117)8.13313550
2chondroitin sulfate catabolic process (GO:0030207)6.29567275
3positive regulation of astrocyte differentiation (GO:0048711)6.23858223
4regulation of timing of cell differentiation (GO:0048505)6.21153997
5innervation (GO:0060384)6.20749258
6negative regulation of sodium ion transport (GO:0010766)5.89819288
7regulation of development, heterochronic (GO:0040034)5.76030366
8regulation of synapse structural plasticity (GO:0051823)5.67877632
9lateral sprouting from an epithelium (GO:0060601)5.56406160
10radial glial cell differentiation (GO:0060019)5.53571599
11tongue development (GO:0043586)4.93036582
12response to auditory stimulus (GO:0010996)4.73444229
13negative regulation of homotypic cell-cell adhesion (GO:0034111)4.69583069
14axon ensheathment in central nervous system (GO:0032291)4.59410744
15central nervous system myelination (GO:0022010)4.59410744
16neuron cell-cell adhesion (GO:0007158)4.58758034
17negative regulation of oligodendrocyte differentiation (GO:0048715)4.58608311
18auditory behavior (GO:0031223)4.51179478
19establishment of nucleus localization (GO:0040023)4.49839514
20regulation of plasminogen activation (GO:0010755)4.49392654
21negative regulation of smoothened signaling pathway (GO:0045879)4.48649993
22regulation of somitogenesis (GO:0014807)4.40098350
23dermatan sulfate biosynthetic process (GO:0030208)4.38058584
24gamma-aminobutyric acid transport (GO:0015812)4.37415880
25otic vesicle formation (GO:0030916)4.36622486
26planar cell polarity pathway involved in neural tube closure (GO:0090179)4.30959213
27regulation of astrocyte differentiation (GO:0048710)4.30724846
28dermatan sulfate metabolic process (GO:0030205)4.25647500
29neuron fate determination (GO:0048664)4.17882667
30neuronal stem cell maintenance (GO:0097150)4.15707419
31postsynaptic membrane organization (GO:0001941)4.12754200
32pattern specification involved in kidney development (GO:0061004)4.12708212
33regulation of penile erection (GO:0060405)4.06204276
34dendritic spine morphogenesis (GO:0060997)3.94652315
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.94015055
36regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.90292067
37regulation of fever generation (GO:0031620)3.88034754
38alanine transport (GO:0032328)3.85773743
39positive regulation of Notch signaling pathway (GO:0045747)3.83360950
40positive regulation of synapse assembly (GO:0051965)3.81917580
41negative regulation of axon extension (GO:0030517)3.81841800
42mechanosensory behavior (GO:0007638)3.78646123
43negative regulation of gliogenesis (GO:0014014)3.75120075
44nephron tubule morphogenesis (GO:0072078)3.69809957
45nephron epithelium morphogenesis (GO:0072088)3.69809957
46regulation of fibroblast growth factor receptor signaling pathway (GO:0040036)3.69437525
47presynaptic membrane assembly (GO:0097105)3.66250775
48negative regulation of adenylate cyclase activity (GO:0007194)3.64004303
49cochlea morphogenesis (GO:0090103)3.62809518
50secretory granule organization (GO:0033363)3.62466317
51positive regulation of glial cell differentiation (GO:0045687)3.62017174
52limb bud formation (GO:0060174)3.58905016
53negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.57097540
54negative regulation of astrocyte differentiation (GO:0048712)3.55196331
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.52194354
56astrocyte differentiation (GO:0048708)3.50632894
57regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.48972929
58mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.48791436
59negative regulation of lyase activity (GO:0051350)3.48668023
60cell-cell signaling involved in cell fate commitment (GO:0045168)3.46143230
61cell morphogenesis involved in neuron differentiation (GO:0048667)3.46041460
62cellular response to cholesterol (GO:0071397)3.45893953
63negative regulation of cyclase activity (GO:0031280)3.45383762
64mesenchyme morphogenesis (GO:0072132)3.45294207
65regulation of oligodendrocyte differentiation (GO:0048713)3.44190755
66negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.44045095
67auditory receptor cell differentiation (GO:0042491)3.42209806
68C4-dicarboxylate transport (GO:0015740)3.40846565
69cranial nerve development (GO:0021545)3.39980401
70glomerular basement membrane development (GO:0032836)3.39464214
71eye photoreceptor cell differentiation (GO:0001754)3.37722241
72photoreceptor cell differentiation (GO:0046530)3.37722241
73vascular smooth muscle contraction (GO:0014829)3.37506277
74viral transcription (GO:0019083)3.37005431
75regulation of heat generation (GO:0031650)3.34638380
76epithelial cilium movement (GO:0003351)3.34166447
77regulation of platelet aggregation (GO:0090330)3.33608392
78calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.31659716
79Notch signaling involved in heart development (GO:0061314)3.30773728
80detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.30500781
81vocalization behavior (GO:0071625)3.27717110
82heart valve formation (GO:0003188)3.27392030
83retinal rod cell development (GO:0046548)3.24295328
84forebrain neuron differentiation (GO:0021879)3.24087218
85oligodendrocyte differentiation (GO:0048709)3.23691596
86forebrain neuron development (GO:0021884)3.23537493
87cholesterol biosynthetic process (GO:0006695)3.20209319
88negative regulation of glial cell differentiation (GO:0045686)3.18085812
89mechanoreceptor differentiation (GO:0042490)3.16534113
90cilium movement (GO:0003341)3.16436866
91energy coupled proton transport, down electrochemical gradient (GO:0015985)3.14528221
92ATP synthesis coupled proton transport (GO:0015986)3.14528221
93nonmotile primary cilium assembly (GO:0035058)3.13210550
94retinal ganglion cell axon guidance (GO:0031290)3.13173663
95translational termination (GO:0006415)3.12030433
96establishment of protein localization to mitochondrial membrane (GO:0090151)3.08987375
97negative regulation of transcription regulatory region DNA binding (GO:2000678)3.08489721
98cilium or flagellum-dependent cell motility (GO:0001539)3.08067097
99regulation of vascular permeability (GO:0043114)3.07174027
100regulation of cell proliferation involved in heart morphogenesis (GO:2000136)3.06577343
101somite rostral/caudal axis specification (GO:0032525)3.06065221
102negative regulation of cAMP biosynthetic process (GO:0030818)3.05971198
103presynaptic membrane organization (GO:0097090)3.05189639
104glial cell differentiation (GO:0010001)3.05175413
105behavioral response to nicotine (GO:0035095)3.04314024
106membrane repolarization (GO:0086009)3.04307246
107regulation of synapse assembly (GO:0051963)3.02106875
108potassium ion import (GO:0010107)3.01925891
109pyrimidine nucleobase catabolic process (GO:0006208)3.01906070
110renal tubule morphogenesis (GO:0061333)3.00049031
111regulation of glial cell differentiation (GO:0045685)2.99720383
112epithelial tube branching involved in lung morphogenesis (GO:0060441)2.99394572
113neural crest cell development (GO:0014032)2.98846843
114heart trabecula morphogenesis (GO:0061384)2.98216654
115regulation of synapse organization (GO:0050807)2.97294842
116neuronal action potential propagation (GO:0019227)2.95600775
117regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.94492225
118negative regulation of cyclic nucleotide biosynthetic process (GO:0030803)2.93819327
119glomerular filtration (GO:0003094)2.93038048
120cerebral cortex radially oriented cell migration (GO:0021799)2.92863789
121neurotransmitter uptake (GO:0001504)2.92419862
122sterol biosynthetic process (GO:0016126)2.91869702
123cGMP-mediated signaling (GO:0019934)2.90455304
124positive regulation of neuroblast proliferation (GO:0002052)2.88202404
125protein refolding (GO:0042026)2.87666661
126nephron tubule formation (GO:0072079)2.87331843
127positive regulation of male gonad development (GO:2000020)2.87195682
128axonemal dynein complex assembly (GO:0070286)2.86808032
129positive regulation of oligodendrocyte differentiation (GO:0048714)2.85808792
130positive regulation of gliogenesis (GO:0014015)2.84445216
131central nervous system projection neuron axonogenesis (GO:0021952)2.83240272
132chondroitin sulfate biosynthetic process (GO:0030206)2.79892361
133endocardial cushion morphogenesis (GO:0003203)2.79222608
134G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.79138673
135negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.78977539
136inner ear receptor cell development (GO:0060119)2.78423517
137regulation of synaptic transmission, glutamatergic (GO:0051966)2.77455662
138layer formation in cerebral cortex (GO:0021819)2.77242844
139dendrite morphogenesis (GO:0048813)2.76774244
140astrocyte development (GO:0014002)2.76123857
141telencephalon development (GO:0021537)2.72424888
142midbrain development (GO:0030901)2.72390653
143negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.72179661
144axonal fasciculation (GO:0007413)2.72127645
145nucleus localization (GO:0051647)2.68941099
146regulation of gliogenesis (GO:0014013)2.66404007
147Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.66299842
148cellular response to sterol (GO:0036315)2.65203163
149midgut development (GO:0007494)2.64517383
150exploration behavior (GO:0035640)2.64446652
151chondrocyte development (GO:0002063)2.64143383
152regulation of respiratory system process (GO:0044065)2.63978762
153central nervous system neuron development (GO:0021954)2.63887485
154neuron recognition (GO:0008038)2.63125374
155negative regulation of platelet activation (GO:0010544)2.62283006
156startle response (GO:0001964)2.62149622
157cochlea development (GO:0090102)2.61967896
158primitive streak formation (GO:0090009)2.61501800
159ribosomal small subunit biogenesis (GO:0042274)2.61361134

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.57022597
2EZH2_27304074_Chip-Seq_ESCs_Mouse3.32565933
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.23799645
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.23293235
5SUZ12_16625203_ChIP-ChIP_MESCs_Mouse3.09999399
6AR_21572438_ChIP-Seq_LNCaP_Human3.02802181
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.97389658
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.94657710
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85163220
10CBX2_27304074_Chip-Seq_ESCs_Mouse2.84222664
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.80969881
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.72005789
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.67968680
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.67968680
15PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.67508488
16ZNF274_21170338_ChIP-Seq_K562_Hela2.66649708
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.59989632
18RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.53580399
19MTF2_20144788_ChIP-Seq_MESCs_Mouse2.39506368
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.35489447
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.34327166
22GBX2_23144817_ChIP-Seq_PC3_Human2.33079102
23HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.32648656
24RBPJ_22232070_ChIP-Seq_NCS_Mouse2.26079316
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.26052590
26EZH2_27294783_Chip-Seq_ESCs_Mouse2.24229023
27IGF1R_20145208_ChIP-Seq_DFB_Human2.05300032
28SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.02996324
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98287801
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.92269214
31TP53_20018659_ChIP-ChIP_R1E_Mouse1.87599317
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.87345459
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83730844
34EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.81945796
35* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.81147237
36POU5F1_16153702_ChIP-ChIP_HESCs_Human1.80712175
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.77080549
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.75048076
39RING1B_27294783_Chip-Seq_NPCs_Mouse1.73414688
40REST_21632747_ChIP-Seq_MESCs_Mouse1.71381294
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67909313
42EWS_26573619_Chip-Seq_HEK293_Human1.63352889
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62661004
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60803482
45VDR_22108803_ChIP-Seq_LS180_Human1.60190421
46OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.46670118
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.44941538
48TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.42866072
49REST_18959480_ChIP-ChIP_MESCs_Mouse1.42691868
50TAF15_26573619_Chip-Seq_HEK293_Human1.41987238
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.41598680
52ER_23166858_ChIP-Seq_MCF-7_Human1.40019834
53P300_19829295_ChIP-Seq_ESCs_Human1.39944332
54AR_25329375_ChIP-Seq_VCAP_Human1.39744618
55ERG_21242973_ChIP-ChIP_JURKAT_Human1.38165856
56* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36330335
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36328665
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35011936
59FUS_26573619_Chip-Seq_HEK293_Human1.34216864
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.32676913
61E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.32229232
62OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30747890
63RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.30060924
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.28907394
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.27236260
66SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26735402
67MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25847968
68SOX2_16153702_ChIP-ChIP_HESCs_Human1.23663045
69TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22479470
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22479470
71DROSHA_22980978_ChIP-Seq_HELA_Human1.22232617
72TP53_16413492_ChIP-PET_HCT116_Human1.20933052
73TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20327909
74SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.19558907
75SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.19139657
76SOX9_26525672_Chip-Seq_HEART_Mouse1.17621500
77RUNX2_22187159_ChIP-Seq_PCA_Human1.15554115
78TP53_18474530_ChIP-ChIP_U2OS_Human1.15534598
79YAP1_20516196_ChIP-Seq_MESCs_Mouse1.15349728
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.14666007
81WT1_19549856_ChIP-ChIP_CCG9911_Human1.14140816
82PIAS1_25552417_ChIP-Seq_VCAP_Human1.13305163
83POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.13143245
84NANOG_18555785_Chip-Seq_ESCs_Mouse1.12846014
85RXR_22108803_ChIP-Seq_LS180_Human1.12246768
86BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12111572
87TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11993951
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11209589
89LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09134986
90BCAT_22108803_ChIP-Seq_LS180_Human1.07905871
91STAT3_23295773_ChIP-Seq_U87_Human1.07327704
92CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06777215
93RNF2_27304074_Chip-Seq_NSC_Mouse1.06554275
94SOX2_21211035_ChIP-Seq_LN229_Gbm1.06029239
95TAL1_26923725_Chip-Seq_HPCs_Mouse1.05531524
96IKZF1_21737484_ChIP-ChIP_HCT116_Human1.05196959
97SMAD4_21799915_ChIP-Seq_A2780_Human1.05156646
98KDM2B_26808549_Chip-Seq_REH_Human1.04822080
99TBX3_20139965_ChIP-Seq_ESCs_Mouse1.03559151
100TBX3_20139965_ChIP-Seq_MESCs_Mouse1.03021082
101CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.00721969
102CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99892599
103JUN_21703547_ChIP-Seq_K562_Human0.98953105
104WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97739937
105* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97045469
106SMAD3_21741376_ChIP-Seq_ESCs_Human0.96606079
107WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96101227
108IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.92106449
109CBP_20019798_ChIP-Seq_JUKART_Human0.92106449
110TCF3_18692474_ChIP-Seq_MEFs_Mouse0.90233526
111ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89800813
112ARNT_22903824_ChIP-Seq_MCF-7_Human0.89376474
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89229824
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.88893054
115MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88852401
116* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88847730
117POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.88635837
118* TRIM28_21343339_ChIP-Seq_HEK293_Human0.88333081
119CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88282982
120ISL1_27105846_Chip-Seq_CPCs_Mouse0.88175686
121TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.87451923
122AR_19668381_ChIP-Seq_PC3_Human0.86838601
123EP300_21415370_ChIP-Seq_HL-1_Mouse0.86238295
124POU5F1_16518401_ChIP-PET_MESCs_Mouse0.86120162
125SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84543017
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84180717
127STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.82850640

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.33146600
2MP0004858_abnormal_nervous_system5.16166320
3MP0009379_abnormal_foot_pigmentation3.61883326
4MP0000778_abnormal_nervous_system3.51163009
5MP0000566_synostosis2.74003779
6MP0004859_abnormal_synaptic_plasticity2.61581172
7MP0002653_abnormal_ependyma_morphology2.51974607
8MP0005423_abnormal_somatic_nervous2.33111817
9MP0000569_abnormal_digit_pigmentation2.25094744
10MP0002736_abnormal_nociception_after2.18295286
11MP0003011_delayed_dark_adaptation2.17078454
12MP0006072_abnormal_retinal_apoptosis2.15016138
13MP0001968_abnormal_touch/_nociception2.07825345
14* MP0003635_abnormal_synaptic_transmissio2.02326338
15MP0009745_abnormal_behavioral_response2.01645088
16MP0005171_absent_coat_pigmentation1.98495328
17MP0002282_abnormal_trachea_morphology1.95273292
18MP0001485_abnormal_pinna_reflex1.94906331
19MP0003634_abnormal_glial_cell1.92136831
20MP0004885_abnormal_endolymph1.92103633
21MP0009384_cardiac_valve_regurgitation1.91394742
22MP0006292_abnormal_olfactory_placode1.81223757
23MP0002928_abnormal_bile_duct1.75200303
24MP0001984_abnormal_olfaction1.72645189
25MP0002064_seizures1.68295087
26MP0001486_abnormal_startle_reflex1.66116436
27MP0000631_abnormal_neuroendocrine_gland1.64408221
28MP0002557_abnormal_social/conspecific_i1.58419585
29MP0002067_abnormal_sensory_capabilities1.58286333
30* MP0002063_abnormal_learning/memory/cond1.57317190
31MP0002751_abnormal_autonomic_nervous1.57046884
32MP0002938_white_spotting1.56048840
33MP0000026_abnormal_inner_ear1.55387032
34MP0002249_abnormal_larynx_morphology1.54580866
35MP0001529_abnormal_vocalization1.54418240
36* MP0002572_abnormal_emotion/affect_behav1.53939173
37MP0004742_abnormal_vestibular_system1.52349866
38MP0004270_analgesia1.46710374
39MP0005174_abnormal_tail_pigmentation1.41079276
40MP0000049_abnormal_middle_ear1.39484647
41MP0002734_abnormal_mechanical_nocicepti1.39176333
42MP0002733_abnormal_thermal_nociception1.37188329
43MP0000955_abnormal_spinal_cord1.36552661
44MP0003122_maternal_imprinting1.34710122
45* MP0002152_abnormal_brain_morphology1.34360152
46MP0002822_catalepsy1.30370620
47MP0003861_abnormal_nervous_system1.30340888
48MP0001958_emphysema1.30200595
49MP0003938_abnormal_ear_development1.29634604
50MP0005084_abnormal_gallbladder_morpholo1.29240002
51MP0002272_abnormal_nervous_system1.25739323
52MP0002184_abnormal_innervation1.23320394
53MP0002095_abnormal_skin_pigmentation1.22283175
54MP0002882_abnormal_neuron_morphology1.19077371
55MP0004134_abnormal_chest_morphology1.17543679
56MP0005187_abnormal_penis_morphology1.16825372
57MP0003755_abnormal_palate_morphology1.16750832
58MP0005551_abnormal_eye_electrophysiolog1.15771625
59MP0003942_abnormal_urinary_system1.15274722
60MP0001905_abnormal_dopamine_level1.13387117
61MP0001293_anophthalmia1.12364335
62MP0009053_abnormal_anal_canal1.11684005
63MP0004142_abnormal_muscle_tone1.11661081
64MP0005253_abnormal_eye_physiology1.09527729
65MP0001970_abnormal_pain_threshold1.09173624
66MP0001299_abnormal_eye_distance/1.09039539
67MP0003880_abnormal_central_pattern1.08502247
68MP0002090_abnormal_vision1.08397249
69MP0005391_vision/eye_phenotype1.08327566
70MP0002932_abnormal_joint_morphology1.06542982
71MP0009046_muscle_twitch1.04757663
72MP0005195_abnormal_posterior_eye1.03991040
73MP0002752_abnormal_somatic_nervous1.03301797
74MP0000762_abnormal_tongue_morphology1.02361319
75MP0002638_abnormal_pupillary_reflex1.02294026
76MP0005623_abnormal_meninges_morphology1.01917229
77MP0003632_abnormal_nervous_system1.00887884
78MP0006276_abnormal_autonomic_nervous1.00493561
79MP0002089_abnormal_postnatal_growth/wei1.00416755
80MP0005248_abnormal_Harderian_gland0.99932323
81MP0002092_abnormal_eye_morphology0.99876569
82MP0005645_abnormal_hypothalamus_physiol0.99710529
83MP0005257_abnormal_intraocular_pressure0.98453066
84MP0003385_abnormal_body_wall0.98265005
85MP0004133_heterotaxia0.97759255
86MP0001502_abnormal_circadian_rhythm0.95014969
87MP0009250_abnormal_appendicular_skeleto0.94508190
88MP0004272_abnormal_basement_membrane0.94162513
89MP0001879_abnormal_lymphatic_vessel0.93759897
90MP0002116_abnormal_craniofacial_bone0.92900249
91MP0005409_darkened_coat_color0.91926399
92MP0000534_abnormal_ureter_morphology0.91743397
93MP0002233_abnormal_nose_morphology0.90383746
94MP0005394_taste/olfaction_phenotype0.90254554
95MP0005499_abnormal_olfactory_system0.90254554
96MP0002697_abnormal_eye_size0.90182576
97MP0000537_abnormal_urethra_morphology0.90098328
98MP0003283_abnormal_digestive_organ0.89912956
99MP0003690_abnormal_glial_cell0.89475574
100MP0002234_abnormal_pharynx_morphology0.89382436
101MP0008789_abnormal_olfactory_epithelium0.87962187
102MP0001270_distended_abdomen0.87191265
103MP0005377_hearing/vestibular/ear_phenot0.86407599
104MP0003878_abnormal_ear_physiology0.86407599
105MP0000467_abnormal_esophagus_morphology0.85509450
106MP0000462_abnormal_digestive_system0.84544037
107MP0001963_abnormal_hearing_physiology0.83743842
108MP0003315_abnormal_perineum_morphology0.83495640
109MP0001943_abnormal_respiration0.82437328
110MP0002102_abnormal_ear_morphology0.81908261
111* MP0002066_abnormal_motor_capabilities/c0.80948430
112MP0000647_abnormal_sebaceous_gland0.80653850
113MP0003937_abnormal_limbs/digits/tail_de0.80638444
114MP0001849_ear_inflammation0.78452663
115MP0001286_abnormal_eye_development0.78251868
116MP0003890_abnormal_embryonic-extraembry0.78137755
117MP0002735_abnormal_chemical_nociception0.77876362
118MP0003633_abnormal_nervous_system0.77446290
119MP0003115_abnormal_respiratory_system0.75478195
120MP0000428_abnormal_craniofacial_morphol0.74386926
121MP0003329_amyloid_beta_deposits0.74268058
122MP0002277_abnormal_respiratory_mucosa0.74150723
123MP0000613_abnormal_salivary_gland0.72811140
124MP0005646_abnormal_pituitary_gland0.72453300
125MP0004924_abnormal_behavior0.71839006
126MP0005386_behavior/neurological_phenoty0.71839006
127MP0000383_abnormal_hair_follicle0.71788697

Predicted human phenotypes

RankGene SetZ-score
1Septo-optic dysplasia (HP:0100842)4.15543058
2True hermaphroditism (HP:0010459)4.10784144
3Abnormality of the 4th metacarpal (HP:0010012)3.96341546
4Esophageal atresia (HP:0002032)3.95247133
5Short 4th metacarpal (HP:0010044)3.80615828
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.80615828
7Myokymia (HP:0002411)3.74155435
8Hemiplegia (HP:0002301)3.70754678
9Gastrointestinal atresia (HP:0002589)3.48642387
10Megalencephaly (HP:0001355)3.40925986
11Rib fusion (HP:0000902)3.39400286
12Coronal craniosynostosis (HP:0004440)3.38365255
13Partial duplication of thumb phalanx (HP:0009944)3.18190763
14Abnormality of glycolysis (HP:0004366)3.18031815
15Increased serum pyruvate (HP:0003542)3.18031815
16Morphological abnormality of the middle ear (HP:0008609)3.03750133
17Abnormal respiratory motile cilium physiology (HP:0012261)2.96169267
18Split foot (HP:0001839)2.96064399
19Missing ribs (HP:0000921)2.95532120
20Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.94019529
21Abnormality of the parietal bone (HP:0002696)2.92665409
22Neonatal short-limb short stature (HP:0008921)2.85044965
23Midline defect of the nose (HP:0004122)2.84205815
24Neoplasm of the heart (HP:0100544)2.79961291
25Vertebral hypoplasia (HP:0008417)2.76702470
26Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.76702470
27Pancreatic fibrosis (HP:0100732)2.76264865
28Partial duplication of the phalanx of hand (HP:0009999)2.76146906
29Hyperventilation (HP:0002883)2.74780778
30Pheochromocytoma (HP:0002666)2.74478911
31Anophthalmia (HP:0000528)2.71441755
32Maternal diabetes (HP:0009800)2.70041959
33Polyphagia (HP:0002591)2.68828728
34Bifid tongue (HP:0010297)2.64781184
35Neuroendocrine neoplasm (HP:0100634)2.61030027
36Aplasia involving bones of the extremities (HP:0009825)2.60971158
37Aplasia involving bones of the upper limbs (HP:0009823)2.60971158
38Aplasia of the phalanges of the hand (HP:0009802)2.60971158
39Abnormal sex determination (HP:0012244)2.53188766
40Sex reversal (HP:0012245)2.53188766
41Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.53108954
42Morphological abnormality of the inner ear (HP:0011390)2.51925517
43Humeroradial synostosis (HP:0003041)2.48619047
44Synostosis involving the elbow (HP:0003938)2.48619047
45Sclerocornea (HP:0000647)2.47320724
46Abnormality of midbrain morphology (HP:0002418)2.47261804
47Molar tooth sign on MRI (HP:0002419)2.47261804
48Medial flaring of the eyebrow (HP:0010747)2.45513556
49Fibular hypoplasia (HP:0003038)2.43625468
50Agitation (HP:0000713)2.42629831
51Hemiparesis (HP:0001269)2.41479106
52Gait imbalance (HP:0002141)2.39763839
53Abnormality of the diencephalon (HP:0010662)2.39661272
54Increased number of teeth (HP:0011069)2.38172978
55Deep venous thrombosis (HP:0002625)2.37982971
56Tarsal synostosis (HP:0008368)2.37895096
57Synostosis involving bones of the feet (HP:0009140)2.37883068
58Synostosis involving bones of the lower limbs (HP:0009138)2.37883068
59Progressive cerebellar ataxia (HP:0002073)2.35720275
60Hamartoma (HP:0010566)2.34783119
61Delayed CNS myelination (HP:0002188)2.34671776
62Nephronophthisis (HP:0000090)2.34522212
63Aplasia/Hypoplasia of the sternum (HP:0006714)2.31088694
64Congenital primary aphakia (HP:0007707)2.28982605
65Absent septum pellucidum (HP:0001331)2.28692647
66Cortical dysplasia (HP:0002539)2.27768412
67Median cleft lip (HP:0000161)2.26512991
68Bilateral microphthalmos (HP:0007633)2.25578661
69Spastic diplegia (HP:0001264)2.25187424
70Parakeratosis (HP:0001036)2.24865456
71Abnormality of dentin (HP:0010299)2.23732282
72Buphthalmos (HP:0000557)2.23049499
73Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.22470008
74Pancreatic cysts (HP:0001737)2.20905574
75Rhinitis (HP:0012384)2.20550976
76Bronchomalacia (HP:0002780)2.20011246
77Supernumerary ribs (HP:0005815)2.18787341
78Mesangial abnormality (HP:0001966)2.15807261
79Hypoplastic left heart (HP:0004383)2.15286973
80Specific learning disability (HP:0001328)2.15097831
81Bilateral sensorineural hearing impairment (HP:0008619)2.14233322
82Reticulocytopenia (HP:0001896)2.11741635
83Oligodactyly (hands) (HP:0001180)2.10604087
84Down-sloping shoulders (HP:0200021)2.08983395
85Hypoplastic pelvis (HP:0008839)2.08566217
86Hyperglycinemia (HP:0002154)2.08156620
87Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.07771756
88Focal motor seizures (HP:0011153)2.07518747
89Aplasia/Hypoplasia of the fibula (HP:0006492)2.07515807
90Postaxial hand polydactyly (HP:0001162)2.06767684
91Bone cyst (HP:0012062)2.06569174
92Hemivertebrae (HP:0002937)2.06022562
93Abnormality of the labia minora (HP:0012880)2.05809640
94Large earlobe (HP:0009748)2.05377751
95Drooling (HP:0002307)2.04499253
96Excessive salivation (HP:0003781)2.04499253
97Postaxial foot polydactyly (HP:0001830)2.04169481
98Oligodactyly (HP:0012165)2.04162476
99Nephrogenic diabetes insipidus (HP:0009806)2.04064307
100Abnormality of the renal medulla (HP:0100957)2.03863118
101Patchy hypopigmentation of hair (HP:0011365)2.03307750
102Genital tract atresia (HP:0001827)2.02777404
103Occipital encephalocele (HP:0002085)2.02631464
104Action tremor (HP:0002345)2.00945075
105Aplasia cutis congenita (HP:0001057)2.00773612
106Atonic seizures (HP:0010819)1.99697377
107Abnormality of the axillary hair (HP:0100134)1.95583367
108Abnormality of secondary sexual hair (HP:0009888)1.95583367
109Abnormal number of incisors (HP:0011064)1.94868401
110Hepatoblastoma (HP:0002884)1.94677800
111Abnormal ciliary motility (HP:0012262)1.93840180
112White forelock (HP:0002211)1.92926025
113Abnormality of the middle phalanges of the toes (HP:0010183)1.92259260
114Absent/shortened dynein arms (HP:0200106)1.92216466
115Dynein arm defect of respiratory motile cilia (HP:0012255)1.92216466
116Short tibia (HP:0005736)1.91737281
117Aplasia/Hypoplasia of the tibia (HP:0005772)1.90722503
118Neonatal respiratory distress (HP:0002643)1.90692110
119Abnormality of the septum pellucidum (HP:0007375)1.90568783
120Synostosis of carpal bones (HP:0005048)1.90249329
121Infantile muscular hypotonia (HP:0008947)1.90116325
122Retinal dysplasia (HP:0007973)1.88689689
123Myelomeningocele (HP:0002475)1.87951717
124Wide anterior fontanel (HP:0000260)1.87531871
125Preaxial foot polydactyly (HP:0001841)1.86762506
126Abnormal respiratory motile cilium morphology (HP:0005938)1.86693876
127Abnormal respiratory epithelium morphology (HP:0012253)1.86693876
128Trigonocephaly (HP:0000243)1.86630150
129Vaginal atresia (HP:0000148)1.86273824
130Restlessness (HP:0000711)1.85010414
131Absent hair (HP:0002298)1.84140366
132Supernumerary bones of the axial skeleton (HP:0009144)1.84113094
133Duplication of thumb phalanx (HP:0009942)1.84061821
134Macrocytic anemia (HP:0001972)1.83993251
135Broad-based gait (HP:0002136)1.83031099
136Aplasia/Hypoplasia of the tongue (HP:0010295)1.82707192
137Hypsarrhythmia (HP:0002521)1.82119419
138Bifid scrotum (HP:0000048)1.81768534
139Abnormal eating behavior (HP:0100738)1.80575510
140Preaxial hand polydactyly (HP:0001177)1.80047920
141Renal dysplasia (HP:0000110)1.79782527
142Ankle clonus (HP:0011448)1.79665875
143Large for gestational age (HP:0001520)1.79332584
144Postural tremor (HP:0002174)1.79193633
145EEG with generalized epileptiform discharges (HP:0011198)1.78367853
14611 pairs of ribs (HP:0000878)1.78157382
147Abnormality of the distal phalanx of the thumb (HP:0009617)1.77105686
148Poor coordination (HP:0002370)1.76628121
149Abnormal auditory evoked potentials (HP:0006958)1.76495993
150Febrile seizures (HP:0002373)1.75935917
151Medulloblastoma (HP:0002885)1.75880065
152Focal seizures (HP:0007359)1.75876614
153Broad face (HP:0000283)1.75752276
154Optic nerve hypoplasia (HP:0000609)1.75721940

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.04648222
2TSSK64.50629327
3WEE14.11884441
4MARK14.07814114
5NTRK23.80218125
6CASK3.62607551
7MAPK133.07157851
8STK242.57178642
9EPHB22.43576279
10TNIK2.39620726
11EPHA32.26130894
12EPHB12.21889862
13KSR12.11200303
14BUB12.02627597
15NTRK32.01199801
16PHKG21.94402774
17PHKG11.94402774
18PAK31.93160022
19NME11.83648574
20ILK1.80787974
21PKN11.80401917
22CAMKK21.78968347
23VRK11.72044829
24MAP3K91.68512593
25ERBB41.58646121
26TYRO31.58611429
27ERBB21.55918314
28CSNK1G31.52057174
29CSNK1G21.51073920
30LMTK21.44448950
31FGR1.37411685
32CSNK1A1L1.36433614
33PAK61.36386724
34DYRK1B1.33754247
35BMPR1B1.29695732
36CSNK1G11.26643700
37SIK11.26532044
38PAK41.25407003
39CAMK1G1.24343821
40DYRK21.24210075
41ERBB31.21390155
42TRIB31.21082884
43MAP4K21.19609997
44CDK31.18948620
45LRRK21.17773377
46PRKD31.16941012
47ROCK21.13011513
48PLK21.10842833
49NTRK11.10649391
50CAMK1D1.10204170
51ROCK11.10050033
52MINK11.06185827
53UHMK11.04822605
54EPHA41.02021089
55CDK50.98837657
56MKNK20.97094738
57PINK10.94789159
58DDR20.89663293
59SIK20.86733115
60DYRK30.85165034
61IRAK10.83640464
62MKNK10.81932496
63GSK3A0.78757819
64WNK40.78309355
65LATS10.76501321
66INSRR0.76304488
67PRKCE0.74672531
68CDK140.74223741
69CAMK2A0.73954699
70BMX0.73465228
71FES0.73308541
72PRKCG0.73018698
73DYRK1A0.72902908
74ADRBK20.72881243
75CDK150.72422763
76ADRBK10.69680585
77CDK180.69425200
78IRAK20.68343215
79CDK11A0.66643270
80FGFR10.66139278
81MAPKAPK50.64856900
82MAP2K70.63325491
83FYN0.63117263
84LATS20.62927875
85NEK90.62552311
86YES10.62094470
87MAP3K40.59741010
88MAP2K20.58937616
89IGF1R0.55256306
90FGFR20.54960130
91PTK60.53276974
92SRC0.52148931
93ALK0.51987886
94PTK2B0.51757376
95CAMKK10.50237459
96TGFBR10.50149450
97STK390.49410351
98PRKCZ0.49106009
99SGK4940.48911722
100SGK2230.48911722
101RET0.47828434
102WNK30.47702397
103MET0.46626975
104PRKACA0.45398322
105PRKG10.44932530
106PNCK0.44785647
107LIMK10.44646981
108AKT20.42814805
109PRKCQ0.42387906
110PRKACG0.42013275
111PLK30.41482347
112BCR0.40560204
113INSR0.39767449
114PAK20.39358266
115MAPK90.39297186
116RPS6KA30.38073023
117PRKD10.37620088
118PRKCA0.37541284
119STK160.37108545
120MOS0.34679436
121CDK190.34667366
122PRKACB0.34215314
123PRKCB0.33725448
124CAMK2D0.33502323
125CSNK1E0.32825416
126SGK20.32554588
127TAF10.30390549
128ARAF0.30154874
129CAMK40.29296293
130CAMK2B0.28030263
131PBK0.28019777
132FRK0.26539300
133GRK10.25095675
134CAMK10.25064464
135RAF10.23044617
136MAPK70.22585160
137BCKDK0.22352314
138KSR20.22246498
139VRK20.21947638
140TAOK10.17864478
141FER0.16592181
142TAOK30.16373784
143RPS6KA50.15126136
144CSNK1A10.14448753
145MAP2K40.13829975
146RPS6KA40.12751486

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009104.39304782
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.08224497
3Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010403.86839278
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.29582428
5Ribosome_Homo sapiens_hsa030102.74217478
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.67013803
7Steroid biosynthesis_Homo sapiens_hsa001002.44985302
8Fatty acid elongation_Homo sapiens_hsa000622.33684268
9Axon guidance_Homo sapiens_hsa043602.22298587
10Butanoate metabolism_Homo sapiens_hsa006502.04709380
11Oxidative phosphorylation_Homo sapiens_hsa001902.02167089
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.89392867
13Parkinsons disease_Homo sapiens_hsa050121.87768596
14GABAergic synapse_Homo sapiens_hsa047271.86166873
15Nicotine addiction_Homo sapiens_hsa050331.80978030
16Basal cell carcinoma_Homo sapiens_hsa052171.80689903
17Glutamatergic synapse_Homo sapiens_hsa047241.80614127
18Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.64627666
19Fatty acid metabolism_Homo sapiens_hsa012121.62205074
20Long-term depression_Homo sapiens_hsa047301.51706135
21Alzheimers disease_Homo sapiens_hsa050101.51349894
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.50864293
23Fatty acid degradation_Homo sapiens_hsa000711.47202883
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.46689969
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.44484384
26Huntingtons disease_Homo sapiens_hsa050161.41953176
27Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.41529872
28Melanogenesis_Homo sapiens_hsa049161.33319110
29Cardiac muscle contraction_Homo sapiens_hsa042601.29624116
30Hedgehog signaling pathway_Homo sapiens_hsa043401.26095592
31Propanoate metabolism_Homo sapiens_hsa006401.22800800
32Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.21518432
33Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.21220600
34Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.20144095
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.19864179
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19102246
37Dorso-ventral axis formation_Homo sapiens_hsa043201.16979180
38Circadian entrainment_Homo sapiens_hsa047131.16873124
39Peroxisome_Homo sapiens_hsa041461.11668833
40Fanconi anemia pathway_Homo sapiens_hsa034601.06900416
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03009255
42Serotonergic synapse_Homo sapiens_hsa047261.00313808
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98752841
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98738981
45* PPAR signaling pathway_Homo sapiens_hsa033200.98445568
46Morphine addiction_Homo sapiens_hsa050320.97943396
47Fatty acid biosynthesis_Homo sapiens_hsa000610.97755067
48Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.96156482
49Pyruvate metabolism_Homo sapiens_hsa006200.94303340
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.91008376
51Cholinergic synapse_Homo sapiens_hsa047250.90948346
52Gap junction_Homo sapiens_hsa045400.89867444
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.89721004
54Renin secretion_Homo sapiens_hsa049240.87026071
55Dopaminergic synapse_Homo sapiens_hsa047280.85357761
56Olfactory transduction_Homo sapiens_hsa047400.84612889
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83753359
58Phototransduction_Homo sapiens_hsa047440.83525551
59beta-Alanine metabolism_Homo sapiens_hsa004100.81666873
60Glycerolipid metabolism_Homo sapiens_hsa005610.80075062
61Gastric acid secretion_Homo sapiens_hsa049710.80042206
62Hippo signaling pathway_Homo sapiens_hsa043900.79930293
63Insulin secretion_Homo sapiens_hsa049110.78716352
64Notch signaling pathway_Homo sapiens_hsa043300.78460970
65Glycosaminoglycan degradation_Homo sapiens_hsa005310.78063961
66Taste transduction_Homo sapiens_hsa047420.77010976
67Dilated cardiomyopathy_Homo sapiens_hsa054140.76680616
68Cocaine addiction_Homo sapiens_hsa050300.75705811
69Wnt signaling pathway_Homo sapiens_hsa043100.75349279
70Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.71837959
71TGF-beta signaling pathway_Homo sapiens_hsa043500.71391524
72Calcium signaling pathway_Homo sapiens_hsa040200.70614981
73Long-term potentiation_Homo sapiens_hsa047200.70542460
74Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.67862301
75Maturity onset diabetes of the young_Homo sapiens_hsa049500.65887047
76Glioma_Homo sapiens_hsa052140.65259466
77Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65073652
78Sulfur metabolism_Homo sapiens_hsa009200.64607649
79Prion diseases_Homo sapiens_hsa050200.63761286
80Folate biosynthesis_Homo sapiens_hsa007900.61757389
81Thyroid hormone synthesis_Homo sapiens_hsa049180.61741517
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60156474
83Arginine biosynthesis_Homo sapiens_hsa002200.58130908
84Ether lipid metabolism_Homo sapiens_hsa005650.57411213
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56360349
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.56091185
87Oxytocin signaling pathway_Homo sapiens_hsa049210.53562152
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.52536999
89Estrogen signaling pathway_Homo sapiens_hsa049150.52492666
902-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52097952
91Sulfur relay system_Homo sapiens_hsa041220.51951175
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51428716
93Tryptophan metabolism_Homo sapiens_hsa003800.50844564
94Protein export_Homo sapiens_hsa030600.50510104
95RNA polymerase_Homo sapiens_hsa030200.49646828
96Primary bile acid biosynthesis_Homo sapiens_hsa001200.49516945
97ECM-receptor interaction_Homo sapiens_hsa045120.48950905
98Salivary secretion_Homo sapiens_hsa049700.48890942
99Melanoma_Homo sapiens_hsa052180.47978237
100Proteoglycans in cancer_Homo sapiens_hsa052050.47440000
101Retinol metabolism_Homo sapiens_hsa008300.46520322
102Circadian rhythm_Homo sapiens_hsa047100.46416240
103Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46299863
104Linoleic acid metabolism_Homo sapiens_hsa005910.45546861
105Renal cell carcinoma_Homo sapiens_hsa052110.44773825
106ErbB signaling pathway_Homo sapiens_hsa040120.44377813
107cAMP signaling pathway_Homo sapiens_hsa040240.43420670
108Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.43052071
109ABC transporters_Homo sapiens_hsa020100.42088122
110Basal transcription factors_Homo sapiens_hsa030220.41020768
111Steroid hormone biosynthesis_Homo sapiens_hsa001400.40411965
112Rap1 signaling pathway_Homo sapiens_hsa040150.40386618
113Bile secretion_Homo sapiens_hsa049760.40187136
114Amphetamine addiction_Homo sapiens_hsa050310.39738109
115Chemical carcinogenesis_Homo sapiens_hsa052040.39272503
116Aldosterone synthesis and secretion_Homo sapiens_hsa049250.38612097
117GnRH signaling pathway_Homo sapiens_hsa049120.36959203
118Endometrial cancer_Homo sapiens_hsa052130.36307631
119African trypanosomiasis_Homo sapiens_hsa051430.36035138
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35636907
121Non-small cell lung cancer_Homo sapiens_hsa052230.35446984
122Colorectal cancer_Homo sapiens_hsa052100.34939688
123Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34750416
124Histidine metabolism_Homo sapiens_hsa003400.33565646
125Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.32127125
126Viral myocarditis_Homo sapiens_hsa054160.31823259
127Alcoholism_Homo sapiens_hsa050340.31468918
128Arginine and proline metabolism_Homo sapiens_hsa003300.29810943
129Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.28189732

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