FABP7P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of timing of cell differentiation (GO:0048505)6.61551715
2secondary heart field specification (GO:0003139)6.36064284
3heart field specification (GO:0003128)6.36064284
4regulation of development, heterochronic (GO:0040034)6.18982723
5positive regulation of cardiac muscle cell differentiation (GO:2000727)5.97995969
6morphogenesis of an endothelium (GO:0003159)5.52260654
7endothelial tube morphogenesis (GO:0061154)5.52260654
8regulation of protein glycosylation (GO:0060049)5.41193436
9presynaptic membrane organization (GO:0097090)4.95382807
10regulation of Wnt signaling pathway involved in heart development (GO:0003307)4.89106027
11specification of organ identity (GO:0010092)4.86437481
12epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)4.82286090
13ventricular trabecula myocardium morphogenesis (GO:0003222)4.75271008
14positive regulation of dendritic spine morphogenesis (GO:0061003)4.59387918
15microtubule depolymerization (GO:0007019)4.56753607
16cerebral cortex radially oriented cell migration (GO:0021799)4.34924449
17positive regulation of male gonad development (GO:2000020)4.32050388
18heart trabecula morphogenesis (GO:0061384)4.27768812
19Notch signaling involved in heart development (GO:0061314)4.21847105
20olfactory bulb development (GO:0021772)4.12009817
21negative regulation of axon guidance (GO:1902668)4.11589426
22somite development (GO:0061053)4.11557769
23limb bud formation (GO:0060174)4.11234415
24regulation of short-term neuronal synaptic plasticity (GO:0048172)4.09762594
25regulation of sarcomere organization (GO:0060297)4.00199202
26protein localization to synapse (GO:0035418)3.96790631
27neural tube formation (GO:0001841)3.95077537
28positive regulation of synapse assembly (GO:0051965)3.89761123
29protein polyglutamylation (GO:0018095)3.81910399
30protein K11-linked deubiquitination (GO:0035871)3.80108179
31startle response (GO:0001964)3.75229909
32DNA integration (GO:0015074)3.73942404
33ganglion development (GO:0061548)3.71938715
34central nervous system projection neuron axonogenesis (GO:0021952)3.69588664
35neuron recognition (GO:0008038)3.64727927
36regulation of respiratory system process (GO:0044065)3.64426596
37axonal fasciculation (GO:0007413)3.63700884
38calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.54641909
39epithelial cell fate commitment (GO:0072148)3.50834832
40cardiac left ventricle morphogenesis (GO:0003214)3.47242934
41intraciliary transport (GO:0042073)3.42211828
42cardiac ventricle formation (GO:0003211)3.41046712
43L-fucose catabolic process (GO:0042355)3.39338338
44fucose catabolic process (GO:0019317)3.39338338
45L-fucose metabolic process (GO:0042354)3.39338338
46retinal rod cell development (GO:0046548)3.38555564
47presynaptic membrane assembly (GO:0097105)3.38106026
48epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.37379331
49negative chemotaxis (GO:0050919)3.36258570
50positive regulation of cell fate commitment (GO:0010455)3.36133087
51regulation of synapse assembly (GO:0051963)3.34500911
52neuron fate determination (GO:0048664)3.33751553
53regulation of chemokine-mediated signaling pathway (GO:0070099)3.32867242
54axon extension involved in axon guidance (GO:0048846)3.32240458
55neuron projection extension involved in neuron projection guidance (GO:1902284)3.32240458
56regulation of cell proliferation involved in heart morphogenesis (GO:2000136)3.31862279
57microtubule severing (GO:0051013)3.30269431
58branched-chain amino acid catabolic process (GO:0009083)3.26600407
59neuroblast proliferation (GO:0007405)3.24979584
60regulation of male gonad development (GO:2000018)3.24459592
61G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.23506647
62regulation of collateral sprouting (GO:0048670)3.23410299
63regulation of cardiac muscle cell differentiation (GO:2000725)3.19939021
64negative regulation of microtubule polymerization (GO:0031115)3.19259705
65hindbrain development (GO:0030902)3.16097250
66DNA double-strand break processing (GO:0000729)3.15731953
67positive regulation of dendritic spine development (GO:0060999)3.13936261
68cardiac chamber formation (GO:0003207)3.11795654
69trabecula morphogenesis (GO:0061383)3.09647981
70regulation of axon guidance (GO:1902667)3.05736441
71postsynaptic membrane organization (GO:0001941)3.03575784
72serotonin metabolic process (GO:0042428)2.99275670
73negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.98270261
74negative regulation of axon extension involved in axon guidance (GO:0048843)2.94347123
75central nervous system neuron axonogenesis (GO:0021955)2.94239186
76regulation of dendritic spine development (GO:0060998)2.90402726
77regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.87993672
78pituitary gland development (GO:0021983)2.87145939
79retinal cone cell development (GO:0046549)2.86730086
80ubiquinone metabolic process (GO:0006743)2.85727008
81fibroblast migration (GO:0010761)2.83931687
82ubiquinone biosynthetic process (GO:0006744)2.79824198
83negative regulation of axon extension (GO:0030517)2.78863395
84behavioral fear response (GO:0001662)2.78770303
85behavioral defense response (GO:0002209)2.78770303
86glial cell proliferation (GO:0014009)2.78573684
87regulation of synapse organization (GO:0050807)2.78355251
88retinal ganglion cell axon guidance (GO:0031290)2.77639845
89establishment of protein localization to Golgi (GO:0072600)2.74552221
90regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.72084380
91response to nitrosative stress (GO:0051409)2.68413055
92neuron cell-cell adhesion (GO:0007158)2.68234710
93microtubule polymerization or depolymerization (GO:0031109)2.67558990
94positive regulation of cardiac muscle cell proliferation (GO:0060045)2.63534541
95regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.62194507
96sympathetic nervous system development (GO:0048485)2.61418257
97regulation of respiratory gaseous exchange (GO:0043576)2.61278006
98single strand break repair (GO:0000012)2.61272690
99regulation of dendritic spine morphogenesis (GO:0061001)2.60053999
100negative regulation of transcription regulatory region DNA binding (GO:2000678)2.59335155

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IGF1R_20145208_ChIP-Seq_DFB_Human4.62301274
2ZFP57_27257070_Chip-Seq_ESCs_Mouse3.25635178
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.25121718
4ZNF274_21170338_ChIP-Seq_K562_Hela3.09874256
5EZH2_22144423_ChIP-Seq_EOC_Human3.04790025
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.97553846
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.88958480
8GBX2_23144817_ChIP-Seq_PC3_Human2.85385045
9TAF15_26573619_Chip-Seq_HEK293_Human2.69605008
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.31237651
11P300_19829295_ChIP-Seq_ESCs_Human2.24501115
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.21608232
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.19319213
14PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.18511011
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.17512538
16FUS_26573619_Chip-Seq_HEK293_Human2.14092383
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.09897700
18SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.04935161
19POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.04721525
20TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.04721525
21ER_23166858_ChIP-Seq_MCF-7_Human2.04049979
22SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.02798571
23PCGF2_27294783_Chip-Seq_ESCs_Mouse2.02078804
24EWS_26573619_Chip-Seq_HEK293_Human2.00445114
25RNF2_27304074_Chip-Seq_NSC_Mouse1.92165575
26PIAS1_25552417_ChIP-Seq_VCAP_Human1.86019338
27OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.81302938
28SMAD4_21799915_ChIP-Seq_A2780_Human1.79313827
29CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.76863277
30SUZ12_27294783_Chip-Seq_NPCs_Mouse1.73300554
31TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.71283978
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.70040946
33CBP_20019798_ChIP-Seq_JUKART_Human1.70040946
34PCGF2_27294783_Chip-Seq_NPCs_Mouse1.69607532
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.67149490
36SMAD3_21741376_ChIP-Seq_EPCs_Human1.66194819
37STAT3_23295773_ChIP-Seq_U87_Human1.66163535
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.66162287
39MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.64181892
40TOP2B_26459242_ChIP-Seq_MCF-7_Human1.62092237
41NANOG_18555785_Chip-Seq_ESCs_Mouse1.61351617
42NR3C1_21868756_ChIP-Seq_MCF10A_Human1.58709457
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.57887547
44TCF4_23295773_ChIP-Seq_U87_Human1.57195666
45AR_25329375_ChIP-Seq_VCAP_Human1.56769871
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.54448825
47TP53_18474530_ChIP-ChIP_U2OS_Human1.54371514
48CDX2_19796622_ChIP-Seq_MESCs_Mouse1.48375133
49TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.44657379
50TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42731179
51EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.42538175
52UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.42125588
53DROSHA_22980978_ChIP-Seq_HELA_Human1.38038829
54AHR_22903824_ChIP-Seq_MCF-7_Human1.36171492
55EZH2_27294783_Chip-Seq_NPCs_Mouse1.35961100
56P53_22387025_ChIP-Seq_ESCs_Mouse1.35136012
57RUNX2_22187159_ChIP-Seq_PCA_Human1.35133871
58CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.35007159
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.34504813
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.34391142
61BCAT_22108803_ChIP-Seq_LS180_Human1.34195149
62TAL1_26923725_Chip-Seq_HPCs_Mouse1.31970470
63NFE2_27457419_Chip-Seq_LIVER_Mouse1.28953419
64KDM2B_26808549_Chip-Seq_REH_Human1.28785846
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.26264139
66GATA1_26923725_Chip-Seq_HPCs_Mouse1.24030556
67TCF4_22108803_ChIP-Seq_LS180_Human1.21940159
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20686194
69CMYC_18555785_Chip-Seq_ESCs_Mouse1.20632172
70SOX2_19829295_ChIP-Seq_ESCs_Human1.20160645
71NANOG_19829295_ChIP-Seq_ESCs_Human1.20160645
72LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19651989
73FLI1_21867929_ChIP-Seq_TH2_Mouse1.19224372
74SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.18244355
75E2F1_18555785_Chip-Seq_ESCs_Mouse1.18185669
76PRDM14_20953172_ChIP-Seq_ESCs_Human1.16575954
77RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15065230
78P53_22127205_ChIP-Seq_FIBROBLAST_Human1.15001179
79TP53_16413492_ChIP-PET_HCT116_Human1.14203720
80SOX2_21211035_ChIP-Seq_LN229_Gbm1.13322914
81TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13249907
82CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13193018
83ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11606032
84NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11246617
85NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11246617
86FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.10700766
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10582097
88SMAD_19615063_ChIP-ChIP_OVARY_Human1.09970665
89CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07845453
90ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07793202
91TBX3_20139965_ChIP-Seq_MESCs_Mouse1.07628498
92STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.06776550
93IRF1_19129219_ChIP-ChIP_H3396_Human1.06654637
94TBX3_20139965_ChIP-Seq_ESCs_Mouse1.06654586
95JUN_21703547_ChIP-Seq_K562_Human1.06359855
96WDR5_24793694_ChIP-Seq_LNCAP_Human1.04670605
97TP53_22573176_ChIP-Seq_HFKS_Human1.03424775
98CRX_20693478_ChIP-Seq_RETINA_Mouse1.01970105
99EP300_21415370_ChIP-Seq_HL-1_Mouse1.01924126
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01543368

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.18840477
2MP0005171_absent_coat_pigmentation3.64577590
3MP0006292_abnormal_olfactory_placode3.38654272
4MP0003880_abnormal_central_pattern3.17554032
5MP0002653_abnormal_ependyma_morphology3.15344979
6MP0003567_abnormal_fetal_cardiomyocyte2.92289518
7MP0000778_abnormal_nervous_system2.71917660
8MP0002234_abnormal_pharynx_morphology2.71455236
9MP0006072_abnormal_retinal_apoptosis2.47535432
10MP0000371_diluted_coat_color2.31454052
11MP0000427_abnormal_hair_cycle2.31339414
12MP0000372_irregular_coat_pigmentation2.28314028
13MP0008789_abnormal_olfactory_epithelium2.19236650
14MP0005360_urolithiasis2.09574449
15MP0003011_delayed_dark_adaptation2.05911677
16MP0003787_abnormal_imprinting2.04098222
17MP0001486_abnormal_startle_reflex2.02609945
18MP0008877_abnormal_DNA_methylation1.93766184
19MP0005551_abnormal_eye_electrophysiolog1.89605345
20MP0003890_abnormal_embryonic-extraembry1.86184100
21MP0005253_abnormal_eye_physiology1.81192881
22MP0005503_abnormal_tendon_morphology1.80800866
23MP0004147_increased_porphyrin_level1.77062598
24MP0005499_abnormal_olfactory_system1.76604682
25MP0005394_taste/olfaction_phenotype1.76604682
26MP0004133_heterotaxia1.61954314
27MP0006054_spinal_hemorrhage1.57176460
28MP0004742_abnormal_vestibular_system1.55320318
29MP0005187_abnormal_penis_morphology1.53790159
30MP0000026_abnormal_inner_ear1.49525950
31MP0001501_abnormal_sleep_pattern1.47615165
32MP0001299_abnormal_eye_distance/1.44911939
33MP0000049_abnormal_middle_ear1.38588131
34MP0000631_abnormal_neuroendocrine_gland1.38470234
35MP0005248_abnormal_Harderian_gland1.34346176
36MP0004885_abnormal_endolymph1.34147349
37MP0005386_behavior/neurological_phenoty1.33972261
38MP0004924_abnormal_behavior1.33972261
39MP0001529_abnormal_vocalization1.33824380
40MP0004272_abnormal_basement_membrane1.33314065
41MP0002752_abnormal_somatic_nervous1.33167773
42MP0003136_yellow_coat_color1.31898395
43MP0003635_abnormal_synaptic_transmissio1.24136494
44MP0005195_abnormal_posterior_eye1.22531368
45MP0002102_abnormal_ear_morphology1.22271510
46MP0002734_abnormal_mechanical_nocicepti1.21267533
47MP0002638_abnormal_pupillary_reflex1.20963861
48MP0004043_abnormal_pH_regulation1.20837751
49MP0000647_abnormal_sebaceous_gland1.20656857
50MP0002075_abnormal_coat/hair_pigmentati1.20228503
51MP0010030_abnormal_orbit_morphology1.19168450
52MP0002095_abnormal_skin_pigmentation1.18004365
53MP0002751_abnormal_autonomic_nervous1.16260145
54MP0002282_abnormal_trachea_morphology1.15814840
55MP0006276_abnormal_autonomic_nervous1.15088760
56MP0002063_abnormal_learning/memory/cond1.14651775
57MP0000383_abnormal_hair_follicle1.11725125
58MP0002882_abnormal_neuron_morphology1.10538879
59MP0001963_abnormal_hearing_physiology1.10232196
60MP0003122_maternal_imprinting1.08887042
61MP0005623_abnormal_meninges_morphology1.08696335
62MP0002067_abnormal_sensory_capabilities1.05114677
63MP0000015_abnormal_ear_pigmentation1.03979927
64MP0009745_abnormal_behavioral_response1.03719416
65MP0002233_abnormal_nose_morphology1.03539403
66MP0002127_abnormal_cardiovascular_syste1.01886200
67MP0005174_abnormal_tail_pigmentation1.01193844
68MP0001293_anophthalmia0.98752870
69MP0004270_analgesia0.97253654
70MP0002938_white_spotting0.91963296
71MP0002160_abnormal_reproductive_system0.91338785
72MP0003121_genomic_imprinting0.90541104
73MP0003861_abnormal_nervous_system0.89884087
74MP0003937_abnormal_limbs/digits/tail_de0.89101503
75MP0000955_abnormal_spinal_cord0.88419350
76MP0001485_abnormal_pinna_reflex0.88158899
77MP0002932_abnormal_joint_morphology0.86305309
78MP0001186_pigmentation_phenotype0.86127088
79MP0002557_abnormal_social/conspecific_i0.86014309
80MP0002090_abnormal_vision0.85707169
81MP0001968_abnormal_touch/_nociception0.85299373
82MP0000751_myopathy0.85205097
83MP0009697_abnormal_copulation0.84689986
84MP0001177_atelectasis0.82929013
85MP0001663_abnormal_digestive_system0.80854437
86MP0002152_abnormal_brain_morphology0.78169268
87MP0002272_abnormal_nervous_system0.77314692
88MP0005391_vision/eye_phenotype0.77083969
89MP0005377_hearing/vestibular/ear_phenot0.75787187
90MP0003878_abnormal_ear_physiology0.75787187
91MP0002572_abnormal_emotion/affect_behav0.74454408
92MP0008569_lethality_at_weaning0.74265141
93MP0003755_abnormal_palate_morphology0.73168887
94MP0004142_abnormal_muscle_tone0.72195552
95MP0001286_abnormal_eye_development0.70302157
96MP0002184_abnormal_innervation0.70011784
97MP0008875_abnormal_xenobiotic_pharmacok0.69827466
98MP0002109_abnormal_limb_morphology0.68709216
99MP0002098_abnormal_vibrissa_morphology0.67058284
100MP0005381_digestive/alimentary_phenotyp0.66505939

Predicted human phenotypes

RankGene SetZ-score
1Adactyly (HP:0009776)4.92876164
2Type II lissencephaly (HP:0007260)4.82431084
3Retinal dysplasia (HP:0007973)4.49206876
4True hermaphroditism (HP:0010459)4.43574823
5Focal motor seizures (HP:0011153)4.02133603
6Broad alveolar ridges (HP:0000187)3.45610702
7Abnormality of midbrain morphology (HP:0002418)3.39548436
8Molar tooth sign on MRI (HP:0002419)3.39548436
9Pancreatic fibrosis (HP:0100732)3.27037383
10Pancreatic cysts (HP:0001737)3.25928319
11Tented upper lip vermilion (HP:0010804)3.15131296
12Neoplasm of the heart (HP:0100544)3.15076799
13Congenital hepatic fibrosis (HP:0002612)3.13218325
14Nephronophthisis (HP:0000090)3.07401828
15Metaphyseal dysplasia (HP:0100255)3.03203740
16Focal seizures (HP:0007359)3.02730436
17Drooling (HP:0002307)3.02074226
18Medial flaring of the eyebrow (HP:0010747)2.97548559
19Neonatal respiratory distress (HP:0002643)2.88980029
20Excessive salivation (HP:0003781)2.80439786
21Chronic hepatic failure (HP:0100626)2.76800257
22Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.68420289
23Short 1st metacarpal (HP:0010034)2.68420289
24Genital tract atresia (HP:0001827)2.56860730
25Poikiloderma (HP:0001029)2.51316574
26Colon cancer (HP:0003003)2.48898785
27Aplasia/Hypoplasia of the tongue (HP:0010295)2.47282399
28Broad-based gait (HP:0002136)2.45728720
29Vaginal atresia (HP:0000148)2.45418456
30Mesomelia (HP:0003027)2.44026570
31Hypothermia (HP:0002045)2.43328608
32Sclerocornea (HP:0000647)2.42096028
33Facial hemangioma (HP:0000329)2.38662344
34Abnormality of the 1st metacarpal (HP:0010009)2.38182379
35Abolished electroretinogram (ERG) (HP:0000550)2.38044938
36Broad ribs (HP:0000885)2.37738610
37Thyroiditis (HP:0100646)2.35747866
38Gait imbalance (HP:0002141)2.31513036
39Abnormality of the renal medulla (HP:0100957)2.31073916
40Bony spicule pigmentary retinopathy (HP:0007737)2.29814030
41Cystic liver disease (HP:0006706)2.26272751
42Ependymoma (HP:0002888)2.25610836
43Congenital primary aphakia (HP:0007707)2.24057407
44Abnormality of the antihelix (HP:0009738)2.23713871
45Hyperventilation (HP:0002883)2.22881941
462-3 toe syndactyly (HP:0004691)2.20724343
47Glioma (HP:0009733)2.20174400
48Septo-optic dysplasia (HP:0100842)2.20055007
49Skull defect (HP:0001362)2.19064020
50Bifid tongue (HP:0010297)2.16536517
51Calf muscle hypertrophy (HP:0008981)2.16120431
52Abnormality of the renal cortex (HP:0011035)2.15432563
53Febrile seizures (HP:0002373)2.12734135
54Poor eye contact (HP:0000817)2.12649395
55Lymphangioma (HP:0100764)2.11441568
56Dialeptic seizures (HP:0011146)2.10050542
57Exotropia (HP:0000577)2.08152542
58Hyperglycinemia (HP:0002154)2.07974636
59Nephrogenic diabetes insipidus (HP:0009806)2.07298159
60Postaxial hand polydactyly (HP:0001162)2.07088297
61Long clavicles (HP:0000890)2.06983985
62Cerebellar dysplasia (HP:0007033)2.04761795
63Short palpebral fissure (HP:0012745)2.03656179
64Lissencephaly (HP:0001339)2.03610990
65Entropion (HP:0000621)2.03567630
66Abnormality of the phalanges of the 2nd finger (HP:0009541)2.02340621
67Concave nail (HP:0001598)2.02003078
68Short phalanx of the thumb (HP:0009660)2.01431804
69Porencephaly (HP:0002132)2.00754962
70Anophthalmia (HP:0000528)2.00638539
71Anencephaly (HP:0002323)1.99729721
72Astrocytoma (HP:0009592)1.98437062
73Abnormality of the astrocytes (HP:0100707)1.98437062
74Aplasia/Hypoplasia of the sternum (HP:0006714)1.96421685
75Occipital encephalocele (HP:0002085)1.96381420
76Tubular atrophy (HP:0000092)1.96001874
77Optic nerve hypoplasia (HP:0000609)1.94924513
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94556479
79High anterior hairline (HP:0009890)1.93584939
80Narrow forehead (HP:0000341)1.92040604
81Abnormal social behavior (HP:0012433)1.88519836
82Impaired social interactions (HP:0000735)1.88519836
83Postaxial foot polydactyly (HP:0001830)1.87008455
84Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.83719496
85Short 5th finger (HP:0009237)1.83473258
86Thin upper lip vermilion (HP:0000219)1.82062799
87Muscle hypertrophy of the lower extremities (HP:0008968)1.82050396
88Abnormality of chromosome stability (HP:0003220)1.80916681
89Hip dysplasia (HP:0001385)1.80349297
90Renal hypoplasia (HP:0000089)1.80108291
91Severe combined immunodeficiency (HP:0004430)1.79881204
92Aplasia/Hypoplasia of the tibia (HP:0005772)1.79321872
93Short humerus (HP:0005792)1.78822543
94Spinal muscular atrophy (HP:0007269)1.76250732
95Abnormal biliary tract physiology (HP:0012439)1.72577829
96Bile duct proliferation (HP:0001408)1.72577829
97Male pseudohermaphroditism (HP:0000037)1.72300630
98Arterial tortuosity (HP:0005116)1.72079677
99Severe Myopia (HP:0011003)1.71656762
100Limited elbow extension (HP:0001377)1.71527340

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK134.96534821
2CLK13.65245179
3CDK193.59965068
4AKT33.47007922
5CCNB13.36924504
6MARK13.33191817
7WNK33.06033627
8UHMK12.47093073
9EPHA42.35933795
10PRKD32.19524125
11CASK2.19396551
12ERBB31.92695023
13NTRK21.92206277
14BCR1.86416963
15FRK1.84758786
16EPHA31.82454146
17DYRK31.80714401
18CAMKK21.73307199
19MAP3K101.68700642
20PAK31.66459418
21NEK11.64370182
22CAMK41.48820682
23MAP3K91.41298647
24MAP4K21.34848940
25TRIM281.32935792
26BMPR1B1.22422603
27MAPK71.18459322
28ZAK1.08963012
29PKN21.03399698
30PKN11.00235370
31CDK81.00094811
32DYRK20.96517088
33SRPK10.96414488
34CDK30.94221758
35TAOK10.93704691
36EPHB20.91790913
37ADRBK20.90429440
38MKNK10.89758894
39ROCK20.86615175
40CSNK1G20.84156670
41MAP3K40.83519552
42ERBB20.83235209
43SGK20.83194565
44CAMK2B0.80806810
45MINK10.78571922
46NEK90.78285611
47NUAK10.78204964
48TAOK30.77930561
49PRKCE0.77218183
50PINK10.73157051
51DYRK1B0.72602194
52TGFBR20.72391108
53MARK20.68986550
54BCKDK0.66552351
55PTK2B0.65281337
56MKNK20.62190435
57MAPK40.58222344
58MAP2K70.57926003
59CSNK1G30.55025205
60CAMK2A0.54427135
61BRSK20.53802056
62ATM0.52381531
63PRKCB0.50944690
64PRKCZ0.49767764
65FER0.49456445
66IRAK10.49316316
67DYRK1A0.48505242
68CSNK1A1L0.47764432
69BRAF0.46279730
70CSNK1G10.44495087
71SGK2230.43596368
72SGK4940.43596368
73CAMK2D0.43568636
74MAPKAPK30.42785889
75SIK30.42512720
76CDK11A0.41222446
77TNIK0.40908246
78KSR10.40890284
79CAMKK10.40163237
80SGK10.39888774
81NTRK30.39379489
82PRKCG0.39136136
83VRK10.38903931
84TXK0.38183213
85MAP3K70.37846326
86CDK50.37387139
87CSNK1A10.34453314
88CAMK10.33571248
89SIK20.33391093
90ATR0.33173020
91PLK30.32949280
92TEC0.32744097
93SGK30.32508028
94PRKACA0.31914848
95INSR0.31584759
96INSRR0.31581191
97PHKG10.31156858
98PHKG20.31156858
99PRKG10.30517324
100CDK180.30418042

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034504.16962550
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.41343176
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.38300632
4Sulfur relay system_Homo sapiens_hsa041223.17963217
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.16431173
6Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.11297309
7Propanoate metabolism_Homo sapiens_hsa006402.47367141
8Protein export_Homo sapiens_hsa030602.41169127
9Nitrogen metabolism_Homo sapiens_hsa009102.37032984
10Primary bile acid biosynthesis_Homo sapiens_hsa001202.26551482
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.19354549
12Nicotine addiction_Homo sapiens_hsa050331.99340788
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.93943645
14Hedgehog signaling pathway_Homo sapiens_hsa043401.86953628
15Steroid biosynthesis_Homo sapiens_hsa001001.82231569
16Taste transduction_Homo sapiens_hsa047421.79446119
17Circadian entrainment_Homo sapiens_hsa047131.73660914
18Glutamatergic synapse_Homo sapiens_hsa047241.69292651
19Olfactory transduction_Homo sapiens_hsa047401.68477593
20Phototransduction_Homo sapiens_hsa047441.59128510
21Axon guidance_Homo sapiens_hsa043601.52563521
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.49149480
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.48441095
24Morphine addiction_Homo sapiens_hsa050321.47620261
25Circadian rhythm_Homo sapiens_hsa047101.34866046
26Basal cell carcinoma_Homo sapiens_hsa052171.34554633
27Butanoate metabolism_Homo sapiens_hsa006501.31690008
28Amphetamine addiction_Homo sapiens_hsa050311.31657613
29Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.29062993
30Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.28847988
31Dopaminergic synapse_Homo sapiens_hsa047281.26751421
32GABAergic synapse_Homo sapiens_hsa047271.19237766
33Notch signaling pathway_Homo sapiens_hsa043301.15920582
34Alcoholism_Homo sapiens_hsa050341.07142760
35Cocaine addiction_Homo sapiens_hsa050301.06944629
36Salivary secretion_Homo sapiens_hsa049701.03027469
37Basal transcription factors_Homo sapiens_hsa030221.00573215
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.96874025
39TGF-beta signaling pathway_Homo sapiens_hsa043500.91476128
40Fanconi anemia pathway_Homo sapiens_hsa034600.90390664
41Wnt signaling pathway_Homo sapiens_hsa043100.89099085
42Serotonergic synapse_Homo sapiens_hsa047260.86904482
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.84419726
44beta-Alanine metabolism_Homo sapiens_hsa004100.77040683
45Fatty acid elongation_Homo sapiens_hsa000620.76781976
46ABC transporters_Homo sapiens_hsa020100.76110222
47Steroid hormone biosynthesis_Homo sapiens_hsa001400.74787197
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72873692
49SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71805802
50Renin secretion_Homo sapiens_hsa049240.70379286
51Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70161470
52Linoleic acid metabolism_Homo sapiens_hsa005910.67800562
53Cholinergic synapse_Homo sapiens_hsa047250.66269699
54Ras signaling pathway_Homo sapiens_hsa040140.60279848
55Caffeine metabolism_Homo sapiens_hsa002320.59524508
56Long-term depression_Homo sapiens_hsa047300.59425242
57Insulin secretion_Homo sapiens_hsa049110.59189066
58cAMP signaling pathway_Homo sapiens_hsa040240.58906352
59Melanogenesis_Homo sapiens_hsa049160.58800231
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.57972095
61Pentose phosphate pathway_Homo sapiens_hsa000300.56407774
62Regulation of autophagy_Homo sapiens_hsa041400.54449988
63Gap junction_Homo sapiens_hsa045400.51948490
64Hippo signaling pathway_Homo sapiens_hsa043900.51803311
65Calcium signaling pathway_Homo sapiens_hsa040200.51320097
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50468643
67Thyroid hormone synthesis_Homo sapiens_hsa049180.50389820
68Ether lipid metabolism_Homo sapiens_hsa005650.50384504
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48656630
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48468879
71Oxytocin signaling pathway_Homo sapiens_hsa049210.47991660
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47639060
73Lysine degradation_Homo sapiens_hsa003100.47281349
74Peroxisome_Homo sapiens_hsa041460.47144669
75Homologous recombination_Homo sapiens_hsa034400.45634602
76MicroRNAs in cancer_Homo sapiens_hsa052060.44427440
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.43257563
78Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43228576
79mRNA surveillance pathway_Homo sapiens_hsa030150.43029200
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42901445
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42631886
82Long-term potentiation_Homo sapiens_hsa047200.41755294
83Gastric acid secretion_Homo sapiens_hsa049710.40840785
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40716076
85RNA degradation_Homo sapiens_hsa030180.39445475
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38710176
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37751039
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37032076
89Inositol phosphate metabolism_Homo sapiens_hsa005620.35408788
90Melanoma_Homo sapiens_hsa052180.35025479
91Colorectal cancer_Homo sapiens_hsa052100.34830051
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34240244
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34111641
94Retinol metabolism_Homo sapiens_hsa008300.34027861
95Sphingolipid metabolism_Homo sapiens_hsa006000.33779325
96Metabolic pathways_Homo sapiens_hsa011000.33359299
97Mineral absorption_Homo sapiens_hsa049780.30817505
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.29816077
99p53 signaling pathway_Homo sapiens_hsa041150.28109115
100Pathways in cancer_Homo sapiens_hsa052000.25712549

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