FAM102A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.55706359
2axon ensheathment in central nervous system (GO:0032291)5.55706359
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.68559756
4antigen processing and presentation of endogenous antigen (GO:0019883)4.60977876
5axon ensheathment (GO:0008366)4.22857750
6ensheathment of neurons (GO:0007272)4.22857750
7myelination (GO:0042552)4.15354808
8regulation of gamma-delta T cell activation (GO:0046643)3.87500556
9positive regulation of gamma-delta T cell activation (GO:0046645)3.86436114
10peptidyl-tyrosine autophosphorylation (GO:0038083)3.85282746
11leukocyte aggregation (GO:0070486)3.84974888
12negative regulation of erythrocyte differentiation (GO:0045647)3.83188730
13histone H3-K36 demethylation (GO:0070544)3.82780263
14myelin maintenance (GO:0043217)3.82031691
15positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.81992967
16negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.68492210
17creatine metabolic process (GO:0006600)3.66163802
18fatty acid elongation (GO:0030497)3.59340683
19positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.58599029
20protein localization to endosome (GO:0036010)3.54338565
21negative regulation of neurotransmitter secretion (GO:0046929)3.51174617
22regulation of histone H3-K27 methylation (GO:0061085)3.47061174
23response to laminar fluid shear stress (GO:0034616)3.35901590
24mannose metabolic process (GO:0006013)3.25745662
25NIK/NF-kappaB signaling (GO:0038061)3.21421529
26negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)3.12446788
27oligodendrocyte differentiation (GO:0048709)3.09383608
28asymmetric protein localization (GO:0008105)3.07493042
29regulation of defense response to virus by virus (GO:0050690)3.05747278
30negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.05343177
31thymic T cell selection (GO:0045061)3.01086479
32regulation of extracellular matrix organization (GO:1903053)3.00616322
33apical protein localization (GO:0045176)2.97798750
34virion attachment to host cell (GO:0019062)2.97337471
35adhesion of symbiont to host cell (GO:0044650)2.97337471
36sodium ion export (GO:0071436)2.96719269
37positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.94715875
38negative T cell selection (GO:0043383)2.93041458
39positive thymic T cell selection (GO:0045059)2.92773947
40adenosine receptor signaling pathway (GO:0001973)2.92177087
41activated T cell proliferation (GO:0050798)2.91630878
42germinal center formation (GO:0002467)2.89817609
43nerve growth factor signaling pathway (GO:0038180)2.88915092
44synaptic vesicle maturation (GO:0016188)2.88286446
45cytoskeletal anchoring at plasma membrane (GO:0007016)2.87342858
46negative thymic T cell selection (GO:0045060)2.87238040
47detection of bacterium (GO:0016045)2.87110336
48response to muramyl dipeptide (GO:0032495)2.86731620
49positive T cell selection (GO:0043368)2.85257901
50negative regulation of lymphocyte mediated immunity (GO:0002707)2.82734786
51regulation of ARF protein signal transduction (GO:0032012)2.82213700
52T-helper cell differentiation (GO:0042093)2.79024630
53CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.79024630
54regulation of isotype switching to IgG isotypes (GO:0048302)2.77218260
55negative regulation of glycoprotein biosynthetic process (GO:0010561)2.76412246
56protein targeting to Golgi (GO:0000042)2.74111665
57T cell migration (GO:0072678)2.73550792
58regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.73256429
59negative regulation of inclusion body assembly (GO:0090084)2.72694074
60T cell selection (GO:0045058)2.72103401
61positive regulation of tolerance induction (GO:0002645)2.71156052
62regulation of B cell receptor signaling pathway (GO:0050855)2.71004578
63regulation of interleukin-4 production (GO:0032673)2.70993718
64regulation of tolerance induction (GO:0002643)2.69926025
65negative regulation of leukocyte mediated immunity (GO:0002704)2.68719383
66positive regulation of Cdc42 GTPase activity (GO:0043089)2.63162860
67protein palmitoylation (GO:0018345)2.62004169
68alpha-beta T cell differentiation (GO:0046632)2.61951562
69negative regulation of neurotransmitter transport (GO:0051589)2.61649543
70detection of other organism (GO:0098543)2.61215475
71antigen receptor-mediated signaling pathway (GO:0050851)2.59888826
72regulation of interleukin-5 production (GO:0032674)2.59198044
73negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.58686762
74positive regulation of interleukin-4 production (GO:0032753)2.58269563
75histone lysine demethylation (GO:0070076)2.56530329
76cellular potassium ion homeostasis (GO:0030007)2.55477618
77potassium ion import (GO:0010107)2.54602055
78negative regulation of cell killing (GO:0031342)2.53746377
79negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.53746377
80COPI coating of Golgi vesicle (GO:0048205)2.53449651
81Golgi transport vesicle coating (GO:0048200)2.53449651
82positive regulation of extracellular matrix organization (GO:1903055)2.53423066
83positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.53091446
84regulation of ARF GTPase activity (GO:0032312)2.52836561
85antigen processing and presentation via MHC class Ib (GO:0002475)2.52047023
86establishment of protein localization to Golgi (GO:0072600)2.51187075
87positive regulation of granulocyte differentiation (GO:0030854)2.50159398
88regulation of amyloid precursor protein catabolic process (GO:1902991)2.49293895
89embryonic process involved in female pregnancy (GO:0060136)2.49053930
90positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.48735393
91phospholipid translocation (GO:0045332)2.48492610
92lipid translocation (GO:0034204)2.48492610
93regulation of beta-amyloid formation (GO:1902003)2.48362145
94regulation of alpha-beta T cell proliferation (GO:0046640)2.47152549
95regulation of regulatory T cell differentiation (GO:0045589)2.46902719
96modulation by virus of host process (GO:0019054)2.45858714
97signal complex assembly (GO:0007172)2.45298308
98cellular response to interleukin-4 (GO:0071353)2.45045809
99tolerance induction (GO:0002507)2.43733169
100histone demethylation (GO:0016577)2.43703565
101L-amino acid import (GO:0043092)2.43592042
102response to type I interferon (GO:0034340)2.43416405
103positive regulation of T cell differentiation in thymus (GO:0033089)2.42755336
104photoreceptor cell differentiation (GO:0046530)2.42676343
105eye photoreceptor cell differentiation (GO:0001754)2.42676343
106macroautophagy (GO:0016236)2.42324261
107B cell receptor signaling pathway (GO:0050853)2.41752931
108histone H3-K9 demethylation (GO:0033169)2.41637213
109ear development (GO:0043583)2.41246612
110response to interleukin-15 (GO:0070672)2.40478706
111negative regulation of cAMP-mediated signaling (GO:0043951)2.40468671
112negative regulation of toll-like receptor signaling pathway (GO:0034122)2.40433758
113regulation of interleukin-2 biosynthetic process (GO:0045076)2.40246438
114negative regulation of JUN kinase activity (GO:0043508)2.39833378
115positive regulation of keratinocyte differentiation (GO:0045618)2.39259136
116B cell homeostasis (GO:0001782)2.38820690
117type I interferon signaling pathway (GO:0060337)2.38755521
118cellular response to type I interferon (GO:0071357)2.38755521
119positive regulation of CREB transcription factor activity (GO:0032793)2.38321571
120adhesion of symbiont to host (GO:0044406)2.37970901
121response to lipoprotein particle (GO:0055094)2.37769990
122long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.36661920
123positive regulation of Rap GTPase activity (GO:0032854)2.36042917
124regulation of type I interferon-mediated signaling pathway (GO:0060338)2.35325292
125alpha-beta T cell activation (GO:0046631)2.34946422
126regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.33449744
127regulation of natural killer cell mediated immunity (GO:0002715)2.33449744
128CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.32925589
129membrane tubulation (GO:0097320)2.32308159
130negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.31373241
131T cell differentiation involved in immune response (GO:0002292)2.30646136
132alpha-beta T cell differentiation involved in immune response (GO:0002293)2.30646136
133alpha-beta T cell activation involved in immune response (GO:0002287)2.30646136
134negative regulation of innate immune response (GO:0045824)2.30598305
135regulation of extracellular matrix disassembly (GO:0010715)2.29220917
136glycosylceramide metabolic process (GO:0006677)2.28529932
137neuronal action potential propagation (GO:0019227)2.28298909
138intestinal absorption (GO:0050892)2.27681467
139cellular response to interleukin-15 (GO:0071350)2.26476355
140potassium ion homeostasis (GO:0055075)2.26105456
141astrocyte development (GO:0014002)2.24677135
142Golgi to endosome transport (GO:0006895)2.24333475
143regulation of interleukin-13 production (GO:0032656)2.23495309
144myelination in peripheral nervous system (GO:0022011)2.23354613
145peripheral nervous system axon ensheathment (GO:0032292)2.23354613
146antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.22512492
147antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.22512492
148regulation of gamma-delta T cell differentiation (GO:0045586)2.22511733
149regulation of synaptic vesicle exocytosis (GO:2000300)2.21879231
150very long-chain fatty acid metabolic process (GO:0000038)2.21621596
151peptide hormone processing (GO:0016486)2.21135179
152regulation of short-term neuronal synaptic plasticity (GO:0048172)2.20916468
153neuronal ion channel clustering (GO:0045161)2.19210617
154intestinal cholesterol absorption (GO:0030299)2.18177108
155transmission of nerve impulse (GO:0019226)2.16856902
156regulation of collateral sprouting (GO:0048670)2.16184607
157regulation of Rap GTPase activity (GO:0032317)2.16175529
158positive regulation of glial cell differentiation (GO:0045687)2.15622052
159endocrine pancreas development (GO:0031018)2.15484853
160T cell receptor signaling pathway (GO:0050852)2.15376381
161Leydig cell differentiation (GO:0033327)2.14074008
162regulation of lipoprotein metabolic process (GO:0050746)2.13563389
163response to hepatocyte growth factor (GO:0035728)2.12602202
164cellular response to hepatocyte growth factor stimulus (GO:0035729)2.12602202
165regulation of T cell tolerance induction (GO:0002664)2.12588288
166cellular response to nerve growth factor stimulus (GO:1990090)2.12091737
167response to nerve growth factor (GO:1990089)2.12091737
168regulation of cholesterol homeostasis (GO:2000188)2.12040412
169retrograde transport, vesicle recycling within Golgi (GO:0000301)2.11686589

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.93826510
2MYC_22102868_ChIP-Seq_BL_Human2.89942593
3VDR_21846776_ChIP-Seq_THP-1_Human2.31931893
4DROSHA_22980978_ChIP-Seq_HELA_Human2.21121826
5VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.20830774
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.19546387
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.12080647
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.11335079
9ELK3_25401928_ChIP-Seq_HUVEC_Human2.10337707
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.07781332
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.01486114
12UTX_26944678_Chip-Seq_JUKART_Human1.94689393
13RUNX_20019798_ChIP-Seq_JUKART_Human1.93883107
14* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.91013031
15MAF_26560356_Chip-Seq_TH2_Human1.84327077
16ESR1_21235772_ChIP-Seq_MCF-7_Human1.83198225
17MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.73041621
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.70016168
19RUNX1_22412390_ChIP-Seq_EML_Mouse1.69884104
20TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68889079
21EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.68271334
22MTF2_20144788_ChIP-Seq_MESCs_Mouse1.65420555
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.63703484
24VDR_24763502_ChIP-Seq_THP-1_Human1.62923196
25ESR2_21235772_ChIP-Seq_MCF-7_Human1.60465168
26SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.59460156
27NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.57142332
28KDM2B_26808549_Chip-Seq_DND41_Human1.55649081
29* MYB_26560356_Chip-Seq_TH1_Human1.55482677
30SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.52350599
31SUZ12_27294783_Chip-Seq_ESCs_Mouse1.51826706
32* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.51143428
33KDM2B_26808549_Chip-Seq_K562_Human1.49824163
34FOXO3_23340844_ChIP-Seq_DLD1_Human1.48489070
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47353621
36RARG_19884340_ChIP-ChIP_MEFs_Mouse1.47243338
37* MYB_26560356_Chip-Seq_TH2_Human1.46794033
38* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.45488107
39KDM2B_26808549_Chip-Seq_SUP-B15_Human1.41964259
40SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.41201327
41CTCF_27219007_Chip-Seq_ERYTHROID_Human1.38877453
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.38837824
43GATA1_19941826_ChIP-Seq_K562_Human1.38531644
44* P68_20966046_ChIP-Seq_HELA_Human1.37984025
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.37662529
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35914614
47SA1_27219007_Chip-Seq_ERYTHROID_Human1.34482260
48RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.34213697
49TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.33578538
50RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.32350314
51EGR1_19374776_ChIP-ChIP_THP-1_Human1.29882736
52EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29545264
53RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29545264
54SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29348058
55IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28576610
56PPARA_22158963_ChIP-Seq_LIVER_Mouse1.27427169
57SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.27210701
58RNF2_27304074_Chip-Seq_ESCs_Mouse1.26834465
59* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26094563
60WT1_25993318_ChIP-Seq_PODOCYTE_Human1.25494606
61GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.23154456
62JARID2_20064375_ChIP-Seq_MESCs_Mouse1.23019001
63WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22850772
64STAT4_19710469_ChIP-ChIP_TH1__Mouse1.22082841
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21891213
66ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21451601
67AR_21572438_ChIP-Seq_LNCaP_Human1.20437298
68KDM2B_26808549_Chip-Seq_JURKAT_Human1.20407628
69IKZF1_21737484_ChIP-ChIP_HCT116_Human1.19025839
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18244944
71LXR_22158963_ChIP-Seq_LIVER_Mouse1.17557787
72REST_21632747_ChIP-Seq_MESCs_Mouse1.16962157
73SPI1_23127762_ChIP-Seq_K562_Human1.16677639
74GATA1_19941827_ChIP-Seq_MEL_Mouse1.15991503
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14974858
76LXR_22292898_ChIP-Seq_THP-1_Human1.14304241
77TET1_21451524_ChIP-Seq_MESCs_Mouse1.13377152
78SCL_19346495_ChIP-Seq_HPC-7_Human1.13041129
79* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.11892502
80SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11824033
81RACK7_27058665_Chip-Seq_MCF-7_Human1.11773449
82* FOXA2_19822575_ChIP-Seq_HepG2_Human1.11697174
83STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.10253109
84* BCOR_27268052_Chip-Seq_Bcells_Human1.09327019
85* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08722337
86* RUNX1_27514584_Chip-Seq_MCF-7_Human1.08566796
87SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08417030
88MYB_21317192_ChIP-Seq_ERMYB_Mouse1.08083201
89REST_18959480_ChIP-ChIP_MESCs_Mouse1.07589714
90MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.07510728
91CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.07177606
92STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06800961
93JARID2_20075857_ChIP-Seq_MESCs_Mouse1.06402826
94* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05699518
95GATA1_22383799_ChIP-Seq_G1ME_Mouse1.05108854
96UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05057034
97CREB1_26743006_Chip-Seq_LNCaP_Human1.04261919
98SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.04131589
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.04054101
100NCOR1_26117541_ChIP-Seq_K562_Human1.03649649
101NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03108913
102CDX2_19796622_ChIP-Seq_MESCs_Mouse1.02702425
103CTCF_27219007_Chip-Seq_Bcells_Human1.01174402
104TRIM28_21343339_ChIP-Seq_HEK293_Human1.01001214
105* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.00882215
106IRF8_27001747_Chip-Seq_BMDM_Mouse0.99822525
107ERG_21242973_ChIP-ChIP_JURKAT_Human0.99545976
108ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98893777
109* TP63_22573176_ChIP-Seq_HFKS_Human0.97962392
110TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97606388
111P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97566421
112NR3C1_23031785_ChIP-Seq_PC12_Mouse0.97323845
113CTNNB1_20460455_ChIP-Seq_HCT116_Human0.96504515
114NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96106891
115SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94933686
116* AHR_22903824_ChIP-Seq_MCF-7_Human0.94586754
117CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.94213974
118SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93652422
119* GATA3_27048872_Chip-Seq_THYMUS_Human0.93398614
120* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93187951
121NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92994183
122TCF7_22412390_ChIP-Seq_EML_Mouse0.92754727
123PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92715980
124ATF3_27146783_Chip-Seq_COLON_Human0.92627367
125AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.92567285
126TET1_21490601_ChIP-Seq_MESCs_Mouse0.91334154
127FOXA1_25552417_ChIP-Seq_VCAP_Human0.91103747
128CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90765604
129ELF1_20517297_ChIP-Seq_JURKAT_Human0.90145366
130TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90114930
131SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.90062940
132SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.89244160
133BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.88342489
134RXR_22108803_ChIP-Seq_LS180_Human0.86862439
135* GATA2_19941826_ChIP-Seq_K562_Human0.85097062
136FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.84958276
137SMAD4_21741376_ChIP-Seq_HESCs_Human0.84110421
138EZH2_27304074_Chip-Seq_ESCs_Mouse0.83803796
139* ARNT_22903824_ChIP-Seq_MCF-7_Human0.83726367
140FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.83569655
141THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83059581
142ESR1_20079471_ChIP-ChIP_T-47D_Human0.82800561
143DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.81375953
144MAF_26560356_Chip-Seq_TH1_Human0.81228575
145* SMC4_20622854_ChIP-Seq_HELA_Human0.81173839
146ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.81132178
147ZFP281_27345836_Chip-Seq_ESCs_Mouse0.79773116
148RXR_22158963_ChIP-Seq_LIVER_Mouse0.79265763
149* PPAR_26484153_Chip-Seq_NCI-H1993_Human0.79233421
150GATA2_21666600_ChIP-Seq_HMVEC_Human0.78939268
151STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.78313956
152KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.78246175
153ZFP281_18757296_ChIP-ChIP_E14_Mouse0.77641370
154EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.77635770

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination3.57003072
2MP0004043_abnormal_pH_regulation3.21111061
3MP0003436_decreased_susceptibility_to3.12755954
4MP0003300_gastrointestinal_ulcer3.10665566
5MP0004270_analgesia2.99220977
6MP0003329_amyloid_beta_deposits2.96225063
7MP0004859_abnormal_synaptic_plasticity2.93906083
8MP0009780_abnormal_chondrocyte_physiolo2.68038758
9MP0004885_abnormal_endolymph2.64325881
10MP0002822_catalepsy2.63306618
11MP0003866_abnormal_defecation2.56272477
12MP0009333_abnormal_splenocyte_physiolog2.39582814
13MP0003690_abnormal_glial_cell2.36321130
14MP0003195_calcinosis2.22293541
15MP0001800_abnormal_humoral_immune2.14117098
16MP0003763_abnormal_thymus_physiology2.08470707
17MP0008260_abnormal_autophagy2.07269316
18MP0003172_abnormal_lysosome_physiology2.05090771
19MP0005000_abnormal_immune_tolerance2.04494727
20MP0010234_abnormal_vibrissa_follicle2.02923175
21MP0004742_abnormal_vestibular_system1.94736604
22MP0002796_impaired_skin_barrier1.93363316
23MP0005310_abnormal_salivary_gland1.92445640
24MP0000703_abnormal_thymus_morphology1.90701854
25MP0003045_fibrosis1.88869489
26MP0008961_abnormal_basal_metabolism1.86906979
27MP0003191_abnormal_cellular_cholesterol1.83331259
28MP0000604_amyloidosis1.81885659
29MP0002272_abnormal_nervous_system1.80638816
30MP0002909_abnormal_adrenal_gland1.80287949
31MP0000685_abnormal_immune_system1.79733124
32MP0003724_increased_susceptibility_to1.76384433
33MP0002420_abnormal_adaptive_immunity1.73698857
34MP0001666_abnormal_nutrient_absorption1.73454633
35MP0001348_abnormal_lacrimal_gland1.73033300
36MP0001819_abnormal_immune_cell1.71527965
37MP0002064_seizures1.70687511
38MP0002723_abnormal_immune_serum1.70322592
39MP0003634_abnormal_glial_cell1.69423534
40MP0003635_abnormal_synaptic_transmissio1.68927223
41MP0003183_abnormal_peptide_metabolism1.68819071
42MP0005025_abnormal_response_to1.67647302
43MP0001485_abnormal_pinna_reflex1.66088803
44MP0003283_abnormal_digestive_organ1.65811165
45MP0000013_abnormal_adipose_tissue1.63179190
46MP0001486_abnormal_startle_reflex1.62201142
47MP0005076_abnormal_cell_differentiation1.59666724
48MP0002398_abnormal_bone_marrow1.58322049
49MP0000003_abnormal_adipose_tissue1.54646561
50MP0003453_abnormal_keratinocyte_physiol1.53688888
51MP0003878_abnormal_ear_physiology1.53513654
52MP0005377_hearing/vestibular/ear_phenot1.53513654
53MP0002452_abnormal_antigen_presenting1.52842579
54MP0002254_reproductive_system_inflammat1.52467201
55MP0008569_lethality_at_weaning1.52316146
56MP0003705_abnormal_hypodermis_morpholog1.51288489
57MP0000462_abnormal_digestive_system1.51098706
58MP0002138_abnormal_hepatobiliary_system1.50444027
59MP0005360_urolithiasis1.49779215
60MP0000716_abnormal_immune_system1.48356944
61MP0001835_abnormal_antigen_presentation1.47482484
62MP0010678_abnormal_skin_adnexa1.45862344
63MP0002933_joint_inflammation1.42845486
64MP0001765_abnormal_ion_homeostasis1.40890616
65MP0003880_abnormal_central_pattern1.40588605
66MP0002009_preneoplasia1.39119169
67MP0002405_respiratory_system_inflammati1.38383036
68MP0001533_abnormal_skeleton_physiology1.36457198
69MP0002166_altered_tumor_susceptibility1.32176515
70MP0002229_neurodegeneration1.32063525
71MP0009745_abnormal_behavioral_response1.29868879
72MP0002419_abnormal_innate_immunity1.28743110
73MP0001501_abnormal_sleep_pattern1.27599969
74MP0005451_abnormal_body_composition1.27596750
75MP0002722_abnormal_immune_system1.27281343
76MP0003303_peritoneal_inflammation1.25485925
77MP0002998_abnormal_bone_remodeling1.23389605
78MP0004381_abnormal_hair_follicle1.21952839
79MP0009840_abnormal_foam_cell1.21022175
80MP0002396_abnormal_hematopoietic_system1.20066150
81MP0003633_abnormal_nervous_system1.19655218
82MP0002693_abnormal_pancreas_physiology1.19447800
83MP0001845_abnormal_inflammatory_respons1.18985338
84MP0000689_abnormal_spleen_morphology1.18709050
85MP0002572_abnormal_emotion/affect_behav1.18503424
86MP0004510_myositis1.17254824
87MP0001873_stomach_inflammation1.16820272
88MP0005671_abnormal_response_to1.16008487
89MP0001849_ear_inflammation1.15887914
90MP0002063_abnormal_learning/memory/cond1.15703612
91MP0003879_abnormal_hair_cell1.13303762
92MP0004185_abnormal_adipocyte_glucose1.13267376
93MP0005075_abnormal_melanosome_morpholog1.12197541
94MP0004264_abnormal_extraembryonic_tissu1.11575405
95MP0002429_abnormal_blood_cell1.11099958
96MP0003091_abnormal_cell_migration1.10668639
97MP0004947_skin_inflammation1.10492187
98MP0001440_abnormal_grooming_behavior1.10257835
99MP0001851_eye_inflammation1.09506214
100MP0002734_abnormal_mechanical_nocicepti1.06877710
101MP0002089_abnormal_postnatal_growth/wei1.01418383
102MP0001944_abnormal_pancreas_morphology0.99361833
103MP0000955_abnormal_spinal_cord0.98049923
104MP0009785_altered_susceptibility_to0.97187044
105MP0003632_abnormal_nervous_system0.96703300
106MP0000465_gastrointestinal_hemorrhage0.96594471
107MP0003631_nervous_system_phenotype0.96294906
108MP0002877_abnormal_melanocyte_morpholog0.96204121
109MP0008875_abnormal_xenobiotic_pharmacok0.95887018
110MP0005058_abnormal_lysosome_morphology0.95836312
111MP0002733_abnormal_thermal_nociception0.95826712
112MP0000858_altered_metastatic_potential0.95785817
113MP0000383_abnormal_hair_follicle0.95585392
114MP0006082_CNS_inflammation0.95260237
115MP0005387_immune_system_phenotype0.94995422
116MP0001790_abnormal_immune_system0.94995422
117MP0003252_abnormal_bile_duct0.94514259
118MP0005375_adipose_tissue_phenotype0.93936257
119MP0001970_abnormal_pain_threshold0.93646149
120MP0005501_abnormal_skin_physiology0.92458358
121MP0003123_paternal_imprinting0.92087554
122MP0001853_heart_inflammation0.91764514
123MP0005365_abnormal_bile_salt0.90441718
124MP0009278_abnormal_bone_marrow0.88739708
125MP0002118_abnormal_lipid_homeostasis0.87825036
126MP0002098_abnormal_vibrissa_morphology0.85396064
127MP0001502_abnormal_circadian_rhythm0.84434975
128MP0005464_abnormal_platelet_physiology0.84085213
129MP0001905_abnormal_dopamine_level0.83255444
130MP0005410_abnormal_fertilization0.82768671
131MP0001664_abnormal_digestion0.81908767
132MP0002132_abnormal_respiratory_system0.80659764
133MP0009643_abnormal_urine_homeostasis0.80343752
134MP0005423_abnormal_somatic_nervous0.78893655
135MP0006072_abnormal_retinal_apoptosis0.77602219
136MP0002066_abnormal_motor_capabilities/c0.77592516
137MP0002139_abnormal_hepatobiliary_system0.77172430
138MP0001216_abnormal_epidermal_layer0.76854703
139MP0002882_abnormal_neuron_morphology0.76246344
140MP0000490_abnormal_crypts_of0.76194734
141MP0000678_abnormal_parathyroid_gland0.75483959
142MP0001663_abnormal_digestive_system0.74609530
143MP0005166_decreased_susceptibility_to0.74270360
144MP0002078_abnormal_glucose_homeostasis0.73893444
145MP0005381_digestive/alimentary_phenotyp0.73892156
146MP0004924_abnormal_behavior0.73722944
147MP0005386_behavior/neurological_phenoty0.73722944
148MP0009115_abnormal_fat_cell0.73706887
149MP0001661_extended_life_span0.73696941
150MP0005666_abnormal_adipose_tissue0.73326537
151MP0003075_altered_response_to0.73168359
152MP0000477_abnormal_intestine_morphology0.73004369
153MP0000609_abnormal_liver_physiology0.72642855
154MP0002148_abnormal_hypersensitivity_rea0.71838545
155MP0002168_other_aberrant_phenotype0.70882057
156MP0005535_abnormal_body_temperature0.70203469
157MP0010155_abnormal_intestine_physiology0.69790203
158MP0005409_darkened_coat_color0.69682562
159MP0005645_abnormal_hypothalamus_physiol0.69304400
160MP0008874_decreased_physiological_sensi0.68626702

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.00611536
2Neurofibrillary tangles (HP:0002185)4.83485195
3Obstructive sleep apnea (HP:0002870)4.71501197
4Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.27004046
5Degeneration of the lateral corticospinal tracts (HP:0002314)4.27004046
6Cerebral inclusion bodies (HP:0100314)3.92372521
7Peripheral hypomyelination (HP:0007182)3.89692623
8Pustule (HP:0200039)3.79766219
9Ankle clonus (HP:0011448)3.77084318
10Sensory axonal neuropathy (HP:0003390)3.76964997
11Papilledema (HP:0001085)3.56339019
12Spastic gait (HP:0002064)3.47871674
13Supranuclear gaze palsy (HP:0000605)3.47740419
14Increased IgE level (HP:0003212)3.45708798
15Abnormality of the corticospinal tract (HP:0002492)3.42497955
16Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.32675146
17Onion bulb formation (HP:0003383)3.32296777
18Increased circulating renin level (HP:0000848)3.30590901
19Metabolic alkalosis (HP:0200114)3.13370379
20Myokymia (HP:0002411)3.13309202
21T lymphocytopenia (HP:0005403)3.05879385
22Hypokalemic alkalosis (HP:0001949)3.01307212
23Abnormality of the fingertips (HP:0001211)2.99623378
24Intention tremor (HP:0002080)2.98653267
25Hyperinsulinemic hypoglycemia (HP:0000825)2.93039182
26Dysmetria (HP:0001310)2.92934198
27Broad face (HP:0000283)2.92514286
28Hypoglycemic seizures (HP:0002173)2.87111430
29Large for gestational age (HP:0001520)2.85445609
30Abnormality of T cell number (HP:0011839)2.76390034
31J-shaped sella turcica (HP:0002680)2.75800792
32Papilloma (HP:0012740)2.73130385
33Verrucae (HP:0200043)2.73130385
34Elevated erythrocyte sedimentation rate (HP:0003565)2.67902249
35Anteriorly placed anus (HP:0001545)2.66693231
36Myositis (HP:0100614)2.65537443
37Abnormal auditory evoked potentials (HP:0006958)2.57012628
38Thin bony cortex (HP:0002753)2.54799156
39Symptomatic seizures (HP:0011145)2.51126720
40Clonus (HP:0002169)2.47025179
41Chronic otitis media (HP:0000389)2.46156931
42Gastrointestinal stroma tumor (HP:0100723)2.45713923
43Slow saccadic eye movements (HP:0000514)2.45388281
44Premature skin wrinkling (HP:0100678)2.45373173
45Abnormality of renin-angiotensin system (HP:0000847)2.45074448
46Seborrheic dermatitis (HP:0001051)2.44360869
47Panhypogammaglobulinemia (HP:0003139)2.42071183
48Nasal polyposis (HP:0100582)2.39363245
49Abnormal delayed hypersensitivity skin test (HP:0002963)2.35922357
50Megalencephaly (HP:0001355)2.34265129
51Abnormality of endocrine pancreas physiology (HP:0012093)2.29984389
52Abnormality of the pancreatic islet cells (HP:0006476)2.29984389
53Malnutrition (HP:0004395)2.29825045
54Gastrointestinal inflammation (HP:0004386)2.29083041
55Abnormality of chloride homeostasis (HP:0011422)2.28499986
56Germ cell neoplasia (HP:0100728)2.27922196
57Growth hormone excess (HP:0000845)2.26597638
58Abnormality of macrophages (HP:0004311)2.26324501
59Micronodular cirrhosis (HP:0001413)2.25105038
60Stridor (HP:0010307)2.24686034
61Insidious onset (HP:0003587)2.23078915
62Termporal pattern (HP:0011008)2.23078915
63Orchitis (HP:0100796)2.21649245
64Atonic seizures (HP:0010819)2.21465072
65Spinal canal stenosis (HP:0003416)2.19403234
66Macroorchidism (HP:0000053)2.19270230
67Stomatitis (HP:0010280)2.19005136
68Recurrent fungal infections (HP:0002841)2.18180300
69Gastrointestinal infarctions (HP:0005244)2.17760461
70Cellulitis (HP:0100658)2.16490110
71Hemorrhage of the eye (HP:0011885)2.15376049
72Vasculitis (HP:0002633)2.15031952
73Thickened helices (HP:0000391)2.12538942
74Meningitis (HP:0001287)2.11294104
75Abnormality of calcium-phosphate metabolism (HP:0100530)2.10948710
76Pheochromocytoma (HP:0002666)2.10239281
77Male infertility (HP:0003251)2.10080207
78Inflammation of the large intestine (HP:0002037)2.09600733
79Hyperkalemia (HP:0002153)2.08846985
80Colitis (HP:0002583)2.08756444
81Urinary urgency (HP:0000012)2.08464260
82Cerebral aneurysm (HP:0004944)2.07781939
83Action tremor (HP:0002345)2.06456753
84Pancreatic islet-cell hyperplasia (HP:0004510)2.06227722
85Subacute progressive viral hepatitis (HP:0006572)2.05013462
86Flat acetabular roof (HP:0003180)2.03251090
87Recurrent abscess formation (HP:0002722)2.02862670
88Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.01890901
89Gingivitis (HP:0000230)2.01871212
90Segmental peripheral demyelination/remyelination (HP:0003481)2.01078587
91Lymphopenia (HP:0001888)2.00733139
92Scanning speech (HP:0002168)2.00648531
93Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.00644528
94Autoimmune hemolytic anemia (HP:0001890)2.00593762
95Cerebral hemorrhage (HP:0001342)2.00430006
96Spastic paraparesis (HP:0002313)2.00294566
97Clumsiness (HP:0002312)2.00275531
98Abnormality of the nasal mucosa (HP:0000433)1.99036058
99Emphysema (HP:0002097)1.98350485
100Recurrent bacterial skin infections (HP:0005406)1.98322368
101Recurrent bronchitis (HP:0002837)1.97274881
102Abnormality of potassium homeostasis (HP:0011042)1.96500100
103Hypokalemia (HP:0002900)1.94947717
104Hyperparathyroidism (HP:0000843)1.94798261
105Testicular neoplasm (HP:0010788)1.94401912
106Basal cell carcinoma (HP:0002671)1.93972203
107Hyperactive renin-angiotensin system (HP:0000841)1.93051209
108Deep venous thrombosis (HP:0002625)1.92923558
109Ileus (HP:0002595)1.92432367
110Dysostosis multiplex (HP:0000943)1.91266748
111Retrobulbar optic neuritis (HP:0100654)1.89781119
112Optic neuritis (HP:0100653)1.89781119
113Hypomagnesemia (HP:0002917)1.89471689
114Interstitial pulmonary disease (HP:0006530)1.89111060
115Decreased circulating renin level (HP:0003351)1.88999667
116Increased CSF protein (HP:0002922)1.86572554
117Prolonged bleeding time (HP:0003010)1.86061363
118Neonatal hypoglycemia (HP:0001998)1.84355744
119Easy fatigability (HP:0003388)1.84164500
120Hemiplegia (HP:0002301)1.83960741
121Chronic diarrhea (HP:0002028)1.83262373
122Annular pancreas (HP:0001734)1.83247316
123Dislocated radial head (HP:0003083)1.82737163
124Abnormality of oral frenula (HP:0000190)1.82460743
125Lower limb muscle weakness (HP:0007340)1.82322497
126Abnormality of polysaccharide metabolism (HP:0011012)1.82172399
127Abnormality of glycosaminoglycan metabolism (HP:0004371)1.82172399
128Abnormality of mucopolysaccharide metabolism (HP:0011020)1.82172399
129Abnormality of T cells (HP:0002843)1.82036261
130Cerebral hypomyelination (HP:0006808)1.82032890
131Abnormality of aromatic amino acid family metabolism (HP:0004338)1.81183711
132Spastic tetraparesis (HP:0001285)1.80975642
133Alacrima (HP:0000522)1.80959030
134Distal upper limb amyotrophy (HP:0007149)1.80600566
135Upper limb amyotrophy (HP:0009129)1.80600566
136Hypercortisolism (HP:0001578)1.80405774
137Hyperphosphatemia (HP:0002905)1.79920108
138Mediastinal lymphadenopathy (HP:0100721)1.79873772
139Hypoglycemic coma (HP:0001325)1.79123510
140Spontaneous hematomas (HP:0007420)1.78612394
141Turricephaly (HP:0000262)1.78197857
142Abnormality of cells of the lymphoid lineage (HP:0012140)1.77613247
143Hyporeflexia of lower limbs (HP:0002600)1.77394710
144Visual hallucinations (HP:0002367)1.77341598
145Polygenic inheritance (HP:0010982)1.76061947
146Recurrent otitis media (HP:0000403)1.75051606
147Recurrent viral infections (HP:0004429)1.74644994
148Deformed sella turcica (HP:0002681)1.73911813
149Lower limb asymmetry (HP:0100559)1.73638555
150Abnormality of the radial head (HP:0003995)1.73198701
151Neuronal loss in central nervous system (HP:0002529)1.72226224
152Ocular albinism (HP:0001107)1.71798515
153Asymmetry of the thorax (HP:0001555)1.69433828
154Restrictive lung disease (HP:0002091)1.68855244
155Villous atrophy (HP:0011473)1.68248732
156Abnormality of small intestinal villus morphology (HP:0011472)1.68248732
157Distal sensory impairment (HP:0002936)1.67610680
158Mucopolysacchariduria (HP:0008155)1.66758155
159Urinary glycosaminoglycan excretion (HP:0003541)1.66758155
160Alkalosis (HP:0001948)1.66462187
161Xanthomatosis (HP:0000991)1.66319952
162Renal salt wasting (HP:0000127)1.63473469
163Joint swelling (HP:0001386)1.63394383
164Protuberant abdomen (HP:0001538)1.63215322
165Overriding aorta (HP:0002623)1.63025628
166Pulmonary infiltrates (HP:0002113)1.62943118
167Abdominal distention (HP:0003270)1.62558792
168Decreased motor nerve conduction velocity (HP:0003431)1.60739078
169Focal motor seizures (HP:0011153)1.60716364
170Abnormality of saccadic eye movements (HP:0000570)1.60512007
171Postural tremor (HP:0002174)1.60178892
172Urinary bladder sphincter dysfunction (HP:0002839)1.60045647
173Abnormality of magnesium homeostasis (HP:0004921)1.59240004
174Hyperaldosteronism (HP:0000859)1.58848176
175Focal seizures (HP:0007359)1.58748048
176Paraparesis (HP:0002385)1.57984062
177Neuroendocrine neoplasm (HP:0100634)1.57185930
178Hammertoe (HP:0001765)1.56416376
179Ketoacidosis (HP:0001993)1.56259782
180Abnormal tarsal ossification (HP:0008369)1.55591601
181Humeroradial synostosis (HP:0003041)1.55354734

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.81165256
2EPHB13.13426735
3WNK42.87948682
4ERN12.67138859
5MAP4K12.51232467
6OXSR12.48225853
7TXK2.45107647
8SMG12.40459578
9PRKD32.40319406
10SIK32.31561481
11TYRO32.27540949
12ICK2.19321800
13ITK2.09651968
14WNK12.09334950
15MAP3K102.07168049
16MAP3K22.03594123
17PRKCH1.94729363
18RIPK41.75759846
19SIK21.70522794
20MAPK151.70292665
21FGFR21.64862645
22NTRK11.62844967
23PRPF4B1.55090163
24EPHA21.54875770
25MST41.54435174
26TYK21.48515668
27FGFR41.45375149
28KSR21.43120672
29PAK61.33918973
30EEF2K1.33601308
31PKN21.32237314
32EPHA41.30059226
33MET1.29291518
34UHMK11.28480029
35INSRR1.26192551
36MAP3K31.25092330
37HIPK21.20573083
38PRKCQ1.18400451
39MARK21.15369659
40PAK31.14357621
41PASK1.12448344
42MAP3K141.11655650
43IRAK41.11503617
44PRKD21.11466013
45STK101.09852692
46MAP2K21.08640483
47BTK1.07911166
48NEK61.07437390
49JAK11.04454770
50MAP3K131.04453838
51MAP3K91.03581748
52GRK61.02268469
53MAP3K10.99145932
54SGK4940.98712818
55SGK2230.98712818
56CSNK1A1L0.98234709
57TBK10.97555092
58CDK190.95785401
59TNIK0.95197008
60MAP3K70.93867060
61CAMK2B0.90499846
62STK380.89987191
63STK110.89883431
64PKN10.89736957
65ROCK20.89671732
66PDPK10.89608358
67CDK50.88345899
68MAP2K30.88038427
69PTK20.87896805
70TRIB30.85728444
71CLK10.85634248
72MAPK120.84487323
73BCR0.84362193
74PDK10.84358088
75CSK0.82863550
76ALK0.82177541
77PTK60.81927445
78PDGFRB0.81003771
79NTRK30.80749227
80ZAP700.77505310
81RET0.77476052
82CHUK0.76833175
83TAOK10.75044443
84PRKD10.71582148
85CSNK1G20.71253589
86IRAK20.70812726
87NLK0.70596197
88DMPK0.69094390
89CAMK1G0.69069451
90CSNK1G10.68735675
91CDK120.68167905
92JAK20.67656812
93MELK0.67167679
94IKBKE0.66931107
95JAK30.66916374
96FYN0.66552072
97NTRK20.66529761
98CSNK1G30.66366683
99LCK0.66221691
100MAPKAPK30.66102945
101CAMKK20.65000625
102MAP3K110.64311806
103MARK30.63925216
104RPS6KB20.63869910
105MAPK110.63783088
106RIPK10.63775410
107MTOR0.61222852
108FES0.60722140
109CAMKK10.59738263
110TESK10.59328129
111MST1R0.58746513
112LRRK20.58037362
113IKBKB0.57962619
114TAOK30.57813546
115MAP2K60.57102246
116CAMK2D0.56904542
117SIK10.56165671
118MAPK70.55523516
119PNCK0.55311021
120IRAK10.55289524
121LMTK20.53673290
122FGFR30.53176408
123IRAK30.53107464
124SGK30.52685416
125WNK30.52412001
126TAOK20.51547869
127BMX0.49480443
128FGR0.49239726
129CAMK2G0.49079445
130SGK20.48453590
131EPHA30.47695159
132RPS6KA20.46749481
133DYRK1B0.46432663
134SYK0.45762534
135PIK3CA0.45224310
136HCK0.44853927
137FGFR10.42388861
138TNK20.41823958
139CDC42BPA0.41551343
140BRD40.40709619
141CSNK1A10.39146122

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049502.59357861
2Nitrogen metabolism_Homo sapiens_hsa009102.48143725
3Sulfur metabolism_Homo sapiens_hsa009202.32981299
4Acute myeloid leukemia_Homo sapiens_hsa052212.29611161
5T cell receptor signaling pathway_Homo sapiens_hsa046601.93907569
6Non-small cell lung cancer_Homo sapiens_hsa052231.71986497
7Endometrial cancer_Homo sapiens_hsa052131.68379765
8Osteoclast differentiation_Homo sapiens_hsa043801.66346076
9Insulin secretion_Homo sapiens_hsa049111.63673606
10Other glycan degradation_Homo sapiens_hsa005111.58658129
11Fatty acid elongation_Homo sapiens_hsa000621.57543767
12Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.55826160
13Dorso-ventral axis formation_Homo sapiens_hsa043201.54787219
14Carbohydrate digestion and absorption_Homo sapiens_hsa049731.54271287
15mTOR signaling pathway_Homo sapiens_hsa041501.44595705
16Chronic myeloid leukemia_Homo sapiens_hsa052201.43244007
17Gastric acid secretion_Homo sapiens_hsa049711.38432473
18Type II diabetes mellitus_Homo sapiens_hsa049301.36280644
19Cocaine addiction_Homo sapiens_hsa050301.35142163
20Hepatitis C_Homo sapiens_hsa051601.34760787
21Notch signaling pathway_Homo sapiens_hsa043301.34595383
22Thyroid cancer_Homo sapiens_hsa052161.33891855
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.33214093
24Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32747346
25Measles_Homo sapiens_hsa051621.29707023
26NF-kappa B signaling pathway_Homo sapiens_hsa040641.27636587
27Primary immunodeficiency_Homo sapiens_hsa053401.27551433
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.24250923
29Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23417533
30Neurotrophin signaling pathway_Homo sapiens_hsa047221.22871194
31Pancreatic cancer_Homo sapiens_hsa052121.22327935
32Pancreatic secretion_Homo sapiens_hsa049721.22182610
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.22070721
34Autoimmune thyroid disease_Homo sapiens_hsa053201.20865465
35Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.20304593
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.18901285
37Long-term potentiation_Homo sapiens_hsa047201.18234892
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.17366897
39Salivary secretion_Homo sapiens_hsa049701.16619213
40Mineral absorption_Homo sapiens_hsa049781.15031075
41Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.14861553
42Thyroid hormone signaling pathway_Homo sapiens_hsa049191.13125264
43Colorectal cancer_Homo sapiens_hsa052101.12648045
44Amphetamine addiction_Homo sapiens_hsa050311.12241534
45Renal cell carcinoma_Homo sapiens_hsa052111.10637881
46GABAergic synapse_Homo sapiens_hsa047271.10272910
47Bile secretion_Homo sapiens_hsa049761.08409609
48Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07894199
49Butanoate metabolism_Homo sapiens_hsa006501.07600500
50Hepatitis B_Homo sapiens_hsa051611.07248109
51TNF signaling pathway_Homo sapiens_hsa046681.06842571
52Steroid biosynthesis_Homo sapiens_hsa001001.05365440
53Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.05068710
54AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.04654393
55Glutamatergic synapse_Homo sapiens_hsa047241.04144675
56Renin secretion_Homo sapiens_hsa049241.03601572
57Morphine addiction_Homo sapiens_hsa050321.03582887
58Toll-like receptor signaling pathway_Homo sapiens_hsa046201.03533100
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02522772
60Circadian entrainment_Homo sapiens_hsa047131.01216313
61Endocytosis_Homo sapiens_hsa041441.00620880
62Fat digestion and absorption_Homo sapiens_hsa049751.00598806
63Dopaminergic synapse_Homo sapiens_hsa047280.99991190
64Prostate cancer_Homo sapiens_hsa052150.99857007
65FoxO signaling pathway_Homo sapiens_hsa040680.99411075
66Cholinergic synapse_Homo sapiens_hsa047250.99189336
67Cyanoamino acid metabolism_Homo sapiens_hsa004600.98061502
68Longevity regulating pathway - mammal_Homo sapiens_hsa042110.97574562
69Axon guidance_Homo sapiens_hsa043600.96682791
70Ether lipid metabolism_Homo sapiens_hsa005650.95723868
71Glioma_Homo sapiens_hsa052140.95558380
72RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94329793
73Jak-STAT signaling pathway_Homo sapiens_hsa046300.94317584
74Insulin signaling pathway_Homo sapiens_hsa049100.93332728
75Toxoplasmosis_Homo sapiens_hsa051450.92112277
76Influenza A_Homo sapiens_hsa051640.91438391
77Leishmaniasis_Homo sapiens_hsa051400.89375209
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.87708844
79Olfactory transduction_Homo sapiens_hsa047400.87376660
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86857226
81Sphingolipid metabolism_Homo sapiens_hsa006000.86447656
82Graft-versus-host disease_Homo sapiens_hsa053320.85551780
83ABC transporters_Homo sapiens_hsa020100.85307239
84Thyroid hormone synthesis_Homo sapiens_hsa049180.84872066
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.83581605
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.81781138
87Histidine metabolism_Homo sapiens_hsa003400.81441624
88Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.78845343
89cAMP signaling pathway_Homo sapiens_hsa040240.78185378
90Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77548597
91Synaptic vesicle cycle_Homo sapiens_hsa047210.77119458
92Inositol phosphate metabolism_Homo sapiens_hsa005620.77115486
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.76828034
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76811027
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76703526
96Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.76583189
97Herpes simplex infection_Homo sapiens_hsa051680.76463476
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.74894281
99ErbB signaling pathway_Homo sapiens_hsa040120.73970194
100Glycerolipid metabolism_Homo sapiens_hsa005610.73493127
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71560248
102Allograft rejection_Homo sapiens_hsa053300.71088999
103Long-term depression_Homo sapiens_hsa047300.69588806
104Apoptosis_Homo sapiens_hsa042100.69374589
105Chemokine signaling pathway_Homo sapiens_hsa040620.69088074
106Estrogen signaling pathway_Homo sapiens_hsa049150.68690318
107Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.68620749
108Platelet activation_Homo sapiens_hsa046110.68196141
109Choline metabolism in cancer_Homo sapiens_hsa052310.68105949
110Tuberculosis_Homo sapiens_hsa051520.67051487
111Vibrio cholerae infection_Homo sapiens_hsa051100.66682434
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.65927881
113Protein export_Homo sapiens_hsa030600.65291566
114VEGF signaling pathway_Homo sapiens_hsa043700.65214929
115HTLV-I infection_Homo sapiens_hsa051660.65194724
116Vitamin digestion and absorption_Homo sapiens_hsa049770.65136985
117HIF-1 signaling pathway_Homo sapiens_hsa040660.64212483
118Glycosaminoglycan degradation_Homo sapiens_hsa005310.63120229
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62743315
120Protein digestion and absorption_Homo sapiens_hsa049740.62191621
121AMPK signaling pathway_Homo sapiens_hsa041520.62095534
122Hematopoietic cell lineage_Homo sapiens_hsa046400.61749988
123Lysosome_Homo sapiens_hsa041420.60586727
124Serotonergic synapse_Homo sapiens_hsa047260.60122788
125Circadian rhythm_Homo sapiens_hsa047100.59687924
126Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59635915
127Type I diabetes mellitus_Homo sapiens_hsa049400.58990141
128Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.58854089
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58742417
130Tight junction_Homo sapiens_hsa045300.57976380
131Viral myocarditis_Homo sapiens_hsa054160.57449645
132Insulin resistance_Homo sapiens_hsa049310.57419763
133Fructose and mannose metabolism_Homo sapiens_hsa000510.57152845
134Prion diseases_Homo sapiens_hsa050200.57106553
135Oxytocin signaling pathway_Homo sapiens_hsa049210.56937227
136Prolactin signaling pathway_Homo sapiens_hsa049170.55434227
137Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54986353
138B cell receptor signaling pathway_Homo sapiens_hsa046620.54681361
139GnRH signaling pathway_Homo sapiens_hsa049120.54581986
140Ras signaling pathway_Homo sapiens_hsa040140.53203794
141Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52489102
142Rap1 signaling pathway_Homo sapiens_hsa040150.51956771
143Intestinal immune network for IgA production_Homo sapiens_hsa046720.51540178
144Epstein-Barr virus infection_Homo sapiens_hsa051690.51359187
145Fatty acid metabolism_Homo sapiens_hsa012120.50726055
146Leukocyte transendothelial migration_Homo sapiens_hsa046700.50404183
147MAPK signaling pathway_Homo sapiens_hsa040100.50354882
148Viral carcinogenesis_Homo sapiens_hsa052030.48513340
149Taste transduction_Homo sapiens_hsa047420.47290480
150Lysine degradation_Homo sapiens_hsa003100.47043513
151Adipocytokine signaling pathway_Homo sapiens_hsa049200.46728314
152Gap junction_Homo sapiens_hsa045400.46323769
153Asthma_Homo sapiens_hsa053100.46294436
154NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45802332
155Fatty acid biosynthesis_Homo sapiens_hsa000610.43565048

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