FAM105A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.11977157
2regulation of B cell receptor signaling pathway (GO:0050855)6.16309885
3negative regulation of cell killing (GO:0031342)5.72299808
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.72299808
5positive regulation of gamma-delta T cell activation (GO:0046645)5.47286703
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.41521303
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.94214175
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.94214175
9antigen processing and presentation of endogenous antigen (GO:0019883)4.83084410
10regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.73743830
11leukocyte aggregation (GO:0070486)4.58852633
12negative thymic T cell selection (GO:0045060)4.56975674
13negative T cell selection (GO:0043383)4.55946632
14neutrophil activation involved in immune response (GO:0002283)4.51938406
15positive thymic T cell selection (GO:0045059)4.41857461
16mast cell activation (GO:0045576)4.40028872
17immunoglobulin mediated immune response (GO:0016064)4.38335282
18positive regulation of myeloid leukocyte mediated immunity (GO:0002888)4.26628424
19interferon-gamma production (GO:0032609)4.23897012
20T cell migration (GO:0072678)4.23487488
21detection of other organism (GO:0098543)4.22738125
22modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.18035850
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.18035850
24positive regulation by organism of defense response of other organism involved in symbiotic interact4.18035850
25modulation by symbiont of host immune response (GO:0052553)4.18035850
26positive regulation by symbiont of host defense response (GO:0052509)4.18035850
27modulation by symbiont of host defense response (GO:0052031)4.18035850
28Arp2/3 complex-mediated actin nucleation (GO:0034314)4.09736689
29regulation of B cell differentiation (GO:0045577)4.08753728
30detection of bacterium (GO:0016045)4.05552059
31regulation of gamma-delta T cell differentiation (GO:0045586)4.03697788
32respiratory burst (GO:0045730)4.00391107
33microglial cell activation (GO:0001774)4.00062045
34regulation of interferon-beta biosynthetic process (GO:0045357)3.99917707
35regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.99631368
36cellular extravasation (GO:0045123)3.98991780
37cellular response to interleukin-15 (GO:0071350)3.92631993
38detection of molecule of bacterial origin (GO:0032490)3.91775497
39response to interleukin-15 (GO:0070672)3.89501350
40sequestering of actin monomers (GO:0042989)3.89219698
41detection of external biotic stimulus (GO:0098581)3.84864971
42positive regulation of B cell differentiation (GO:0045579)3.80463134
43thymic T cell selection (GO:0045061)3.79263591
44positive regulation of leukocyte degranulation (GO:0043302)3.79170755
45regulation of gamma-delta T cell activation (GO:0046643)3.76799804
46positive T cell selection (GO:0043368)3.75477758
47myeloid cell activation involved in immune response (GO:0002275)3.75078762
48positive regulation of antigen processing and presentation (GO:0002579)3.74731111
49macrophage activation involved in immune response (GO:0002281)3.72747409
50B cell receptor signaling pathway (GO:0050853)3.70696590
51positive regulation of chemokine secretion (GO:0090197)3.69380339
52negative regulation of interleukin-12 production (GO:0032695)3.65654093
53positive regulation of mast cell activation (GO:0033005)3.65244833
54hepatocyte apoptotic process (GO:0097284)3.62743684
55regulation of tolerance induction (GO:0002643)3.60674372
56positive regulation of lamellipodium assembly (GO:0010592)3.49484884
57regulation of myeloid leukocyte mediated immunity (GO:0002886)3.49241965
58regulation of T cell tolerance induction (GO:0002664)3.47386512
59regulation of mast cell activation involved in immune response (GO:0033006)3.45674162
60mature B cell differentiation (GO:0002335)3.45378909
61macrophage activation (GO:0042116)3.44585650
62negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.44215252
63B cell mediated immunity (GO:0019724)3.42805435
64tolerance induction (GO:0002507)3.40500301
65antigen processing and presentation via MHC class Ib (GO:0002475)3.40311955
66T cell selection (GO:0045058)3.40271527
67detection of biotic stimulus (GO:0009595)3.39453944
68neutrophil activation (GO:0042119)3.38857411
69regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.36545094
70regulation of natural killer cell mediated immunity (GO:0002715)3.36545094
71regulation of T cell receptor signaling pathway (GO:0050856)3.36181221
72mast cell activation involved in immune response (GO:0002279)3.35286929
73mast cell degranulation (GO:0043303)3.35286929
74antigen receptor-mediated signaling pathway (GO:0050851)3.35165970
75myeloid dendritic cell activation (GO:0001773)3.32790027
76negative regulation of phagocytosis (GO:0050765)3.26749941
77regulation of leukocyte degranulation (GO:0043300)3.26462284
78T cell receptor signaling pathway (GO:0050852)3.26451341
79T cell costimulation (GO:0031295)3.26055559
80cellular response to zinc ion (GO:0071294)3.25358006
81positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.24622469
82negative regulation of granulocyte differentiation (GO:0030853)3.23191263
83regulation of antigen processing and presentation (GO:0002577)3.22427890
84lymphocyte costimulation (GO:0031294)3.20802650
85interferon-gamma-mediated signaling pathway (GO:0060333)3.20727116
86actin nucleation (GO:0045010)3.19482791
87positive regulation of interferon-alpha production (GO:0032727)3.19005898
88regulation of isotype switching to IgG isotypes (GO:0048302)3.17321132
89pinocytosis (GO:0006907)3.16039770
90granulocyte activation (GO:0036230)3.12727306
91mature B cell differentiation involved in immune response (GO:0002313)3.11710821
92positive regulation of macrophage differentiation (GO:0045651)3.09168708
93positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.08931355
94positive regulation of natural killer cell mediated immunity (GO:0002717)3.08931355
95neutrophil mediated immunity (GO:0002446)3.07885579
96cellular defense response (GO:0006968)3.07548482
97regulation of interferon-alpha production (GO:0032647)3.06786543
98production of molecular mediator involved in inflammatory response (GO:0002532)3.03645976
99leukocyte degranulation (GO:0043299)3.02290674
100response to host immune response (GO:0052572)3.02188579
101response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.02188579
102myeloid leukocyte activation (GO:0002274)3.02001449
103regulation of alpha-beta T cell proliferation (GO:0046640)3.01520476
104positive regulation of lamellipodium organization (GO:1902745)3.01142829
105regulation of interleukin-12 biosynthetic process (GO:0045075)3.00391689
106regulation of mast cell activation (GO:0033003)2.99611890
107myeloid dendritic cell differentiation (GO:0043011)2.98262102
108energy homeostasis (GO:0097009)2.97589642
109response to peptidoglycan (GO:0032494)2.97504991
110regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.97019278
111cellular response to interferon-gamma (GO:0071346)2.96272215
112defense response to protozoan (GO:0042832)2.95885230
113regulation of mast cell degranulation (GO:0043304)2.95288176
114leukocyte cell-cell adhesion (GO:0007159)2.94751036
115regulation of hypersensitivity (GO:0002883)2.94560750
116positive regulation of regulated secretory pathway (GO:1903307)2.93322015
117negative regulation of interleukin-1 beta production (GO:0032691)2.93268730
118negative regulation of T cell mediated immunity (GO:0002710)2.91232286
119cellular response to interferon-beta (GO:0035458)2.90318240
120response to protozoan (GO:0001562)2.90007309
121positive regulation of cellular amide metabolic process (GO:0034250)2.89701169
122glycosphingolipid catabolic process (GO:0046479)2.88633545
123regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.87598403
124negative regulation of lymphocyte mediated immunity (GO:0002707)2.86772522
125positive regulation of mast cell degranulation (GO:0043306)2.86247010
126positive regulation of mast cell activation involved in immune response (GO:0033008)2.86247010
127G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.85909136
128response to interferon-gamma (GO:0034341)2.80720275
129histamine secretion (GO:0001821)2.79313586
130purine nucleotide salvage (GO:0032261)2.76281028
131myeloid leukocyte mediated immunity (GO:0002444)2.75931325
132homocysteine metabolic process (GO:0050667)2.75509545
133positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.73715227
134positive regulation of alpha-beta T cell proliferation (GO:0046641)2.73643439
135adenosine metabolic process (GO:0046085)2.72090906
136glycolipid catabolic process (GO:0019377)2.71256862
137positive regulation of tolerance induction (GO:0002645)2.68697573
138positive regulation of toll-like receptor signaling pathway (GO:0034123)2.66618070
139negative regulation of acute inflammatory response (GO:0002674)2.66504143
140regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.65941744
141neutrophil chemotaxis (GO:0030593)2.64655570
142tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.64487390
143RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.64487390
144regulation of regulated secretory pathway (GO:1903305)2.63764018

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.43126867
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.24344316
3IRF8_21731497_ChIP-ChIP_J774_Mouse5.20254477
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.73141607
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse4.08926625
6BP1_19119308_ChIP-ChIP_Hs578T_Human4.05873090
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.89567771
8* IRF8_27001747_Chip-Seq_BMDM_Mouse3.79418319
9SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.63743556
10STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.43753994
11NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.18112590
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.13489064
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.12434087
14RUNX_20019798_ChIP-Seq_JUKART_Human3.04648868
15STAT4_19710469_ChIP-ChIP_TH1__Mouse3.00370617
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.99468025
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.92329137
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.92191116
19FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.88087765
20MYB_26560356_Chip-Seq_TH2_Human2.78749692
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.75049076
22SPI1_23547873_ChIP-Seq_NB4_Human2.72225508
23SCL_19346495_ChIP-Seq_HPC-7_Human2.68402742
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.57754665
25MAF_26560356_Chip-Seq_TH1_Human2.56442517
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.39360153
27* RUNX1_22412390_ChIP-Seq_EML_Mouse2.32641178
28VDR_21846776_ChIP-Seq_THP-1_Human2.31200570
29MYC_22102868_ChIP-Seq_BL_Human2.30778665
30MYB_26560356_Chip-Seq_TH1_Human2.29794163
31FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.27960980
32* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.24923184
33SPI1_23127762_ChIP-Seq_K562_Human2.19555879
34VDR_24763502_ChIP-Seq_THP-1_Human2.18211920
35UTX_26944678_Chip-Seq_JUKART_Human2.15415480
36MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.09492887
37E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.06775588
38Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.93824790
39E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.90696448
40NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.90435120
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.85202388
42NOTCH1_21737748_ChIP-Seq_TLL_Human1.84535140
43E2F7_22180533_ChIP-Seq_HELA_Human1.82482936
44GATA3_27048872_Chip-Seq_THYMUS_Human1.81777417
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.73325865
46TCF7_22412390_ChIP-Seq_EML_Mouse1.69725334
47PU_27001747_Chip-Seq_BMDM_Mouse1.69683969
48PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.68949896
49LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.68617805
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64984141
51SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.63107242
52CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.54722187
53MAF_26560356_Chip-Seq_TH2_Human1.51810084
54VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.49806975
55GATA2_22383799_ChIP-Seq_G1ME_Mouse1.46437963
56* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.43666435
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.43061766
58GATA1_22025678_ChIP-Seq_K562_Human1.41217046
59ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33732025
60PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.31919597
61KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.31779711
62GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.30688634
63GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.30359555
64GATA3_26560356_Chip-Seq_TH2_Human1.30168380
65* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.27489508
66BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.24043612
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21898564
68KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20611470
69GATA1_22383799_ChIP-Seq_G1ME_Mouse1.19958458
70* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19863449
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15604599
72KDM2B_26808549_Chip-Seq_DND41_Human1.15194029
73SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14797203
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.14082713
75VDR_24787735_ChIP-Seq_THP-1_Human1.13751549
76TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13556815
77KDM2B_26808549_Chip-Seq_SUP-B15_Human1.12687249
78* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07729455
79GATA1_19941827_ChIP-Seq_MEL_Mouse1.05906954
80NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.05616790
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05149841
82STAT1_20625510_ChIP-Seq_HELA_Human1.04341286
83CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.03884086
84RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.02285996
85BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99992343
86FLI1_27457419_Chip-Seq_LIVER_Mouse0.99484971
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97414034
88STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.97070392
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96699433
90* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96041753
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95923453
92ELK3_25401928_ChIP-Seq_HUVEC_Human0.95747060
93EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.95541991
94SMRT_27268052_Chip-Seq_Bcells_Human0.94335135
95* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93934115
96FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.92922990
97* CDX2_22108803_ChIP-Seq_LS180_Human0.92647097
98GATA3_26560356_Chip-Seq_TH1_Human0.89462838
99IKZF1_21737484_ChIP-ChIP_HCT116_Human0.85674923
100BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.84577715
101CEBPB_22108803_ChIP-Seq_LS180_Human0.83739734
102STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83634757
103SMAD_19615063_ChIP-ChIP_OVARY_Human0.83619222
104* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.81838932
105CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.81423887
106RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81375364
107* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81071799
108VDR_23849224_ChIP-Seq_CD4+_Human0.79878731
109TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.78917203
110EGR1_23403033_ChIP-Seq_LIVER_Mouse0.78540171
111SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78477208
112TFEB_21752829_ChIP-Seq_HELA_Human0.78391358
113SALL4_22934838_ChIP-ChIP_CD34+_Human0.78082257
114SPI1_20517297_ChIP-Seq_HL60_Human0.77748024
115LXR_22292898_ChIP-Seq_THP-1_Human0.77143443
116CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.76194638
117VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.76191509
118NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.75189329
119RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.74553655
120EZH2_27294783_Chip-Seq_NPCs_Mouse0.74275322
121GATA2_19941826_ChIP-Seq_K562_Human0.73944341
122GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72041500
123GATA2_21666600_ChIP-Seq_HMVEC_Human0.70830797
124BCAT_22108803_ChIP-Seq_LS180_Human0.69969572
125ETS1_22383799_ChIP-Seq_G1ME_Mouse0.69651451

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.82033593
2MP0005671_abnormal_response_to4.36174359
3MP0006082_CNS_inflammation3.17750277
4MP0005000_abnormal_immune_tolerance3.15414388
5MP0003436_decreased_susceptibility_to3.11688360
6MP0003763_abnormal_thymus_physiology3.09759379
7MP0009785_altered_susceptibility_to3.06494259
8MP0001800_abnormal_humoral_immune2.99547119
9MP0002419_abnormal_innate_immunity2.97136723
10MP0002148_abnormal_hypersensitivity_rea2.96958627
11MP0005025_abnormal_response_to2.89780678
12MP0002452_abnormal_antigen_presenting2.88628688
13MP0000685_abnormal_immune_system2.86869369
14MP0002723_abnormal_immune_serum2.86657066
15MP0002420_abnormal_adaptive_immunity2.84659169
16MP0001819_abnormal_immune_cell2.84059954
17MP0001790_abnormal_immune_system2.74245157
18MP0005387_immune_system_phenotype2.74245157
19MP0003303_peritoneal_inflammation2.64282231
20MP0005058_abnormal_lysosome_morphology2.50560733
21MP0005464_abnormal_platelet_physiology2.47543217
22MP0002166_altered_tumor_susceptibility2.46720198
23MP0002398_abnormal_bone_marrow2.35270023
24MP0003724_increased_susceptibility_to2.33755603
25MP0000716_abnormal_immune_system2.24062479
26MP0002405_respiratory_system_inflammati2.22462290
27MP0003172_abnormal_lysosome_physiology2.22136318
28MP0009333_abnormal_splenocyte_physiolog2.16125347
29MP0002396_abnormal_hematopoietic_system2.11524646
30MP0005360_urolithiasis2.11425425
31MP0004510_myositis2.05394335
32MP0002006_tumorigenesis2.04184321
33MP0000689_abnormal_spleen_morphology1.97126066
34MP0001853_heart_inflammation1.94497810
35MP0002722_abnormal_immune_system1.92728224
36MP0001845_abnormal_inflammatory_respons1.84603371
37MP0010155_abnormal_intestine_physiology1.83511466
38MP0002429_abnormal_blood_cell1.82454974
39MP0003191_abnormal_cellular_cholesterol1.81486271
40MP0003300_gastrointestinal_ulcer1.80154822
41MP0005174_abnormal_tail_pigmentation1.75949319
42MP0001873_stomach_inflammation1.71707505
43MP0003183_abnormal_peptide_metabolism1.65104832
44MP0000703_abnormal_thymus_morphology1.63686951
45MP0005310_abnormal_salivary_gland1.61134546
46MP0001533_abnormal_skeleton_physiology1.60940885
47MP0003806_abnormal_nucleotide_metabolis1.60059842
48MP0004947_skin_inflammation1.56980944
49MP0005670_abnormal_white_adipose1.53321834
50MP0008469_abnormal_protein_level1.51554133
51MP0000465_gastrointestinal_hemorrhage1.49603709
52MP0000343_altered_response_to1.49572940
53MP0000858_altered_metastatic_potential1.46831615
54MP0003866_abnormal_defecation1.45667685
55MP0003448_altered_tumor_morphology1.42734364
56MP0002933_joint_inflammation1.36499990
57MP0005451_abnormal_body_composition1.25841235
58MP0002998_abnormal_bone_remodeling1.23881660
59MP0005075_abnormal_melanosome_morpholog1.23758128
60MP0010234_abnormal_vibrissa_follicle1.19525214
61MP0001545_abnormal_hematopoietic_system1.19183932
62MP0005397_hematopoietic_system_phenotyp1.19183932
63MP0000516_abnormal_urinary_system1.18579634
64MP0005367_renal/urinary_system_phenotyp1.18579634
65MP0001851_eye_inflammation1.17882768
66MP0000015_abnormal_ear_pigmentation1.15508392
67MP0003075_altered_response_to1.13437877
68MP0004808_abnormal_hematopoietic_stem1.11841517
69MP0005164_abnormal_response_to1.11155310
70MP0009764_decreased_sensitivity_to1.05346602
71MP0008995_early_reproductive_senescence1.04671907
72MP0009840_abnormal_foam_cell1.02669436
73MP0004883_abnormal_blood_vessel1.01596345
74MP0005166_decreased_susceptibility_to1.00533263
75MP0000490_abnormal_crypts_of1.00277262
76MP0005646_abnormal_pituitary_gland0.99454591
77MP0000013_abnormal_adipose_tissue0.92547942
78MP0000569_abnormal_digit_pigmentation0.92367392
79MP0002277_abnormal_respiratory_mucosa0.90470274
80MP0001765_abnormal_ion_homeostasis0.90068371
81MP0001661_extended_life_span0.88995122
82MP0005319_abnormal_enzyme/_coenzyme0.88879687
83MP0005332_abnormal_amino_acid0.88706842
84MP0001756_abnormal_urination0.88123240
85MP0000604_amyloidosis0.86910301
86MP0009278_abnormal_bone_marrow0.85996893
87MP0001986_abnormal_taste_sensitivity0.85799015
88MP0009643_abnormal_urine_homeostasis0.85623463
89MP0009763_increased_sensitivity_to0.82018460
90MP0005085_abnormal_gallbladder_physiolo0.81166488
91MP0003252_abnormal_bile_duct0.76429642
92MP0008004_abnormal_stomach_pH0.76218840
93MP0003195_calcinosis0.76190490
94MP0002095_abnormal_skin_pigmentation0.75746575
95MP0003045_fibrosis0.74957010
96MP0000249_abnormal_blood_vessel0.73924566
97MP0002019_abnormal_tumor_incidence0.73856230
98MP0003828_pulmonary_edema0.72904975
99MP0004185_abnormal_adipocyte_glucose0.71212970
100MP0008873_increased_physiological_sensi0.70819412
101MP0003787_abnormal_imprinting0.69792097
102MP0002009_preneoplasia0.68786984
103MP0005647_abnormal_sex_gland0.68035993
104MP0004147_increased_porphyrin_level0.67964681
105MP0008007_abnormal_cellular_replicative0.67889989
106MP0002138_abnormal_hepatobiliary_system0.66308657
107MP0003795_abnormal_bone_structure0.64024511
108MP0001663_abnormal_digestive_system0.60247300
109MP0003690_abnormal_glial_cell0.59832268
110MP0002928_abnormal_bile_duct0.59000418
111MP0005390_skeleton_phenotype0.59000347
112MP0004381_abnormal_hair_follicle0.57785749
113MP0000371_diluted_coat_color0.54216434
114MP0002693_abnormal_pancreas_physiology0.51418970
115MP0002136_abnormal_kidney_physiology0.50320213
116MP0009765_abnormal_xenobiotic_induced0.49682667
117MP0010307_abnormal_tumor_latency0.49451398
118MP0003656_abnormal_erythrocyte_physiolo0.47521582
119MP0010352_gastrointestinal_tract_polyps0.45010030
120MP0005076_abnormal_cell_differentiation0.42782825
121MP0003566_abnormal_cell_adhesion0.41998779
122MP0000920_abnormal_myelination0.41324855
123MP0002132_abnormal_respiratory_system0.40439040
124MP0008874_decreased_physiological_sensi0.40189401
125MP0006054_spinal_hemorrhage0.39849687
126MP0005023_abnormal_wound_healing0.39368154
127MP0003638_abnormal_response/metabolism_0.38452128
128MP0000609_abnormal_liver_physiology0.37818763

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.22942138
2Eczematoid dermatitis (HP:0000976)5.73427897
3Recurrent bacterial skin infections (HP:0005406)5.35050502
4Elevated erythrocyte sedimentation rate (HP:0003565)5.22597665
5Myositis (HP:0100614)4.53857768
6Recurrent fungal infections (HP:0002841)4.39101014
7Recurrent cutaneous fungal infections (HP:0011370)4.16417493
8Chronic mucocutaneous candidiasis (HP:0002728)4.16417493
9T lymphocytopenia (HP:0005403)4.13000799
10Systemic lupus erythematosus (HP:0002725)4.10992766
11Recurrent skin infections (HP:0001581)4.08053028
12Chronic obstructive pulmonary disease (HP:0006510)4.07619868
13Obstructive lung disease (HP:0006536)4.07619868
14Stomatitis (HP:0010280)4.02947189
15Increased cerebral lipofuscin (HP:0011813)3.99518344
16Increased neuronal autofluorescent lipopigment (HP:0002074)3.96629777
17Abnormality of T cell number (HP:0011839)3.96508773
18IgM deficiency (HP:0002850)3.94708454
19Recurrent gram-negative bacterial infections (HP:0005420)3.88294361
20Abnormality of liposaccharide metabolism (HP:0010968)3.80931185
21Abnormality of glycosphingolipid metabolism (HP:0004343)3.80931185
22Abnormality of glycolipid metabolism (HP:0010969)3.80931185
23Abnormality of macrophages (HP:0004311)3.74454529
24Mediastinal lymphadenopathy (HP:0100721)3.67457646
25Anorexia (HP:0002039)3.65096029
26Pulmonary embolism (HP:0002204)3.64759093
27Vacuolated lymphocytes (HP:0001922)3.59956758
28Constricted visual fields (HP:0001133)3.59248148
29Recurrent viral infections (HP:0004429)3.56755283
30Chronic otitis media (HP:0000389)3.51704711
31Severe combined immunodeficiency (HP:0004430)3.45579612
32Recurrent bronchitis (HP:0002837)3.37845706
33Abnormality of T cells (HP:0002843)3.35389420
34Meningitis (HP:0001287)3.33854577
35Glomerulonephritis (HP:0000099)3.30788235
36Gingivitis (HP:0000230)3.28984265
37Chronic diarrhea (HP:0002028)3.25702694
38Thyroiditis (HP:0100646)3.23715184
39Congenital sensorineural hearing impairment (HP:0008527)3.23705198
40Combined immunodeficiency (HP:0005387)3.19784058
41Abnormality of alanine metabolism (HP:0010916)3.17688862
42Hyperalaninemia (HP:0003348)3.17688862
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.17688862
44Gingival bleeding (HP:0000225)3.15312463
45Orchitis (HP:0100796)3.15278709
46Dysostosis multiplex (HP:0000943)3.13642786
47Panhypogammaglobulinemia (HP:0003139)3.13600139
48Pustule (HP:0200039)3.09056884
49Retrobulbar optic neuritis (HP:0100654)3.04622598
50Optic neuritis (HP:0100653)3.04622598
51Leukocytosis (HP:0001974)3.04579928
52Abnormality of eosinophils (HP:0001879)3.03101492
53Fatigue (HP:0012378)2.99218202
54Agnosia (HP:0010524)2.97905732
55Myocardial infarction (HP:0001658)2.97861608
56Abnormality of the vasculature of the conjunctiva (HP:0008054)2.88585918
57Abnormal delayed hypersensitivity skin test (HP:0002963)2.86179282
58Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.85871714
59Conjunctival telangiectasia (HP:0000524)2.85672957
60Vasculitis (HP:0002633)2.83676488
61Inflammation of the large intestine (HP:0002037)2.83638986
62Spontaneous hematomas (HP:0007420)2.83526412
63Thrombocytosis (HP:0001894)2.80503512
64IgG deficiency (HP:0004315)2.78700487
65Eosinophilia (HP:0001880)2.75715211
66Disinhibition (HP:0000734)2.72878098
67Gastrointestinal inflammation (HP:0004386)2.70592138
68Petechiae (HP:0000967)2.69199915
69Hemoptysis (HP:0002105)2.68535589
70Thrombophlebitis (HP:0004418)2.67787732
71Agammaglobulinemia (HP:0004432)2.62911740
72Pulmonary infiltrates (HP:0002113)2.62833769
73Nasal polyposis (HP:0100582)2.61024390
74Decreased electroretinogram (ERG) amplitude (HP:0000654)2.60415254
75Amyloidosis (HP:0011034)2.58790571
76Esophageal varix (HP:0002040)2.58726779
77Abnormality of T cell physiology (HP:0011840)2.55387036
78Lymphopenia (HP:0001888)2.53032380
79Hypoplasia of the thymus (HP:0000778)2.49443725
80Colitis (HP:0002583)2.49127742
81Abnormality of the pleura (HP:0002103)2.45593669
82Granulocytopenia (HP:0001913)2.41363701
83Abnormality of cells of the lymphoid lineage (HP:0012140)2.41263632
84Basal ganglia calcification (HP:0002135)2.40038175
85Gangrene (HP:0100758)2.39942938
86Autoimmune thrombocytopenia (HP:0001973)2.39171171
87Hypergammaglobulinemia (HP:0010702)2.39012401
88Cellulitis (HP:0100658)2.38837005
89Periodontitis (HP:0000704)2.33565342
90Prolonged bleeding time (HP:0003010)2.33461110
91Epistaxis (HP:0000421)2.31566508
92Axonal loss (HP:0003447)2.31073059
93Abnormality of the prostate (HP:0008775)2.30893383
94Hematochezia (HP:0002573)2.29778368
95Abnormality of the nasal mucosa (HP:0000433)2.29189653
96Increased IgM level (HP:0003496)2.27449455
97Mucopolysacchariduria (HP:0008155)2.26315981
98Urinary glycosaminoglycan excretion (HP:0003541)2.26315981
99Encephalitis (HP:0002383)2.25826295
100Interstitial pulmonary disease (HP:0006530)2.25098014
101Abnormality of the pericardium (HP:0001697)2.21886471
102Autoimmune hemolytic anemia (HP:0001890)2.21751591
103Abnormality of the basal ganglia (HP:0002134)2.17708768
104Arterial thrombosis (HP:0004420)2.16248448
105Thoracic kyphosis (HP:0002942)2.15909888
106Urticaria (HP:0001025)2.15202524
107Abnormality of B cell number (HP:0010975)2.15114770
108B lymphocytopenia (HP:0010976)2.15114770
109Increased IgE level (HP:0003212)2.13876757
110Keratoconjunctivitis sicca (HP:0001097)2.13836789
111Chest pain (HP:0100749)2.13351543
112Loss of speech (HP:0002371)2.12031092
113Abnormality of polysaccharide metabolism (HP:0011012)2.11501441
114Abnormality of glycosaminoglycan metabolism (HP:0004371)2.11501441
115Abnormality of mucopolysaccharide metabolism (HP:0011020)2.11501441
116Recurrent sinusitis (HP:0011108)2.09240522
117Polyneuropathy (HP:0001271)2.08881295
118Cheilitis (HP:0100825)2.07045243
119Impaired platelet aggregation (HP:0003540)2.06644742
120Abnormal platelet function (HP:0011869)2.06644742
121Purpura (HP:0000979)2.06385948
122Patchy hypopigmentation of hair (HP:0011365)2.03344937
123Pancreatitis (HP:0001733)2.02689676
124White forelock (HP:0002211)2.01463363
125Restrictive lung disease (HP:0002091)1.99331662
126Keratoconjunctivitis (HP:0001096)1.98505052
127Hepatosplenomegaly (HP:0001433)1.97545000
128Gastrointestinal infarctions (HP:0005244)1.96389195
129Cerebral ischemia (HP:0002637)1.92833609
130Episodic fever (HP:0001954)1.92736024
131Glomerulopathy (HP:0100820)1.91733489
132Abnormality of homocysteine metabolism (HP:0010919)1.90090915
133Homocystinuria (HP:0002156)1.90090915
134Pigmentary retinal degeneration (HP:0001146)1.89768162
135Microcytic anemia (HP:0001935)1.88035383
136Mucosal telangiectasiae (HP:0100579)1.86503592
137Paresthesia (HP:0003401)1.80682363
138Peritonitis (HP:0002586)1.79145145
139Hyperglycemia (HP:0003074)1.78626758
140Vertigo (HP:0002321)1.78060072
141Insulin-resistant diabetes mellitus (HP:0000831)1.77124223

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.37059776
2TXK4.08247462
3BLK3.20046375
4ACVR1B3.12354959
5TGFBR23.08764412
6IRAK43.06855665
7TYK22.89667489
8ZAP702.80158377
9RIPK42.79016858
10KIT2.68362687
11CSF1R2.59533915
12FRK2.58958326
13ITK2.54122634
14TBK12.38380297
15MAP3K142.32846068
16JAK32.28927262
17IKBKE2.15133669
18TEC2.12488828
19SYK1.87026406
20MAP3K121.85935524
21NME21.81071348
22BTK1.79639400
23JAK11.77692231
24FES1.75603740
25MAP3K131.75109002
26STK101.72171931
27LCK1.70740168
28GRK71.65643411
29HCK1.60950821
30CSK1.59872350
31GRK61.51244009
32FLT31.50413605
33CLK11.47302871
34IKBKB1.42389289
35KDR1.41317659
36TRPM71.39735061
37LYN1.36858861
38IRAK31.36726748
39YES11.29504779
40MAPK151.16080444
41NEK91.15806705
42TESK21.09345761
43JAK21.07040380
44TAOK31.06055894
45FGFR41.05200850
46MAP2K31.04003937
47ADRBK21.01076051
48TSSK60.90010544
49SGK20.88868249
50OXSR10.85013512
51ERN10.84011624
52PKN20.83564285
53SIK20.83474924
54MAP2K60.80431694
55FGFR30.79263553
56CDK90.78011300
57MATK0.77190649
58RPS6KA40.77100679
59NLK0.76363211
60SCYL20.76141924
61FGR0.73679118
62MAP3K20.73060873
63RPS6KB20.71966985
64CAMKK20.71825237
65NEK60.69957634
66VRK10.68158303
67MAP3K10.66415190
68MARK30.65565101
69SGK2230.64493518
70SGK4940.64493518
71PRKCQ0.64373314
72PIM10.62972816
73LRRK20.61392983
74SGK30.61281015
75TNK20.61101901
76PRPF4B0.59862649
77PIM20.59480657
78PDK10.56622818
79PDPK10.54515660
80PAK40.54478737
81SIK30.52802447
82MAP2K20.51050619
83STK110.50651155
84TAOK10.50639848
85DAPK10.50470841
86CHUK0.49837649
87FYN0.48727234
88DAPK20.48324997
89PRKCD0.47967484
90BMPR20.47751279
91MAPK120.45771602
92PDK20.44818787
93MYLK0.43433208
94PRKAA20.43106485
95ILK0.42171620
96PASK0.40047398
97IGF1R0.39342760
98HIPK20.39241247
99RAF10.38963925
100MAPKAPK20.38309263
101CAMKK10.38096391
102EPHB10.37911963
103ERBB30.35930154
104ABL10.35648768
105MOS0.35073549
106MAPK40.33349250
107ADRBK10.32873736
108MST40.31703160
109IRAK10.30406370
110RPS6KA60.30314730
111PTK60.30296769
112PIK3CG0.29223284
113STK240.28948700
114SGK10.28683357
115EGFR0.27900631
116MAP2K10.26798448
117CDK60.26724056
118EIF2AK30.26078514
119IRAK20.25406917
120MAP3K100.25200693
121INSR0.24159229
122TLK10.23558012
123PRKG20.23252483
124RPS6KC10.22986752
125RPS6KL10.22986752
126PRKCH0.21904908
127CDK190.20995512
128EEF2K0.20563551
129STK40.20376869
130MAP3K110.20000686
131MAPK70.19947449
132EIF2AK10.18238844
133MAP3K30.17676093

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.46514018
2Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.88355897
3Antigen processing and presentation_Homo sapiens_hsa046122.87465272
4Leishmaniasis_Homo sapiens_hsa051402.83545045
5Other glycan degradation_Homo sapiens_hsa005112.68719763
6Osteoclast differentiation_Homo sapiens_hsa043802.62861608
7Staphylococcus aureus infection_Homo sapiens_hsa051502.43016766
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.32436640
9Measles_Homo sapiens_hsa051622.24963327
10T cell receptor signaling pathway_Homo sapiens_hsa046602.24150611
11Graft-versus-host disease_Homo sapiens_hsa053322.23552506
12B cell receptor signaling pathway_Homo sapiens_hsa046622.20793486
13Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.11796419
14NF-kappa B signaling pathway_Homo sapiens_hsa040642.11425857
15Glycosaminoglycan degradation_Homo sapiens_hsa005312.07881122
16Maturity onset diabetes of the young_Homo sapiens_hsa049502.06220360
17Hematopoietic cell lineage_Homo sapiens_hsa046402.05421084
18Lysosome_Homo sapiens_hsa041422.04478979
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.99278070
20Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.91684280
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.83710586
22Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.78649793
23Allograft rejection_Homo sapiens_hsa053301.77828007
24Pertussis_Homo sapiens_hsa051331.69931717
25Tuberculosis_Homo sapiens_hsa051521.66205702
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.58044863
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.57000432
28Collecting duct acid secretion_Homo sapiens_hsa049661.55138086
29RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.53011157
30Chemokine signaling pathway_Homo sapiens_hsa040621.51299312
31Legionellosis_Homo sapiens_hsa051341.42313503
32Toxoplasmosis_Homo sapiens_hsa051451.38715374
33Asthma_Homo sapiens_hsa053101.36836754
34Shigellosis_Homo sapiens_hsa051311.34040950
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.32108884
36Jak-STAT signaling pathway_Homo sapiens_hsa046301.31395125
37Salmonella infection_Homo sapiens_hsa051321.28097745
38Regulation of autophagy_Homo sapiens_hsa041401.27185871
39Herpes simplex infection_Homo sapiens_hsa051681.25861965
40Malaria_Homo sapiens_hsa051441.24367320
41Leukocyte transendothelial migration_Homo sapiens_hsa046701.22818607
42Influenza A_Homo sapiens_hsa051641.21018876
43Apoptosis_Homo sapiens_hsa042101.16914739
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16244004
45Viral myocarditis_Homo sapiens_hsa054161.13920174
46Sulfur metabolism_Homo sapiens_hsa009201.12278521
47Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.12107864
48Hepatitis B_Homo sapiens_hsa051611.08514829
49Acute myeloid leukemia_Homo sapiens_hsa052211.06551971
50Platelet activation_Homo sapiens_hsa046111.04810493
51Rheumatoid arthritis_Homo sapiens_hsa053231.03501006
52Phagosome_Homo sapiens_hsa041450.98554668
53Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.97664343
54Systemic lupus erythematosus_Homo sapiens_hsa053220.97641655
55Pancreatic cancer_Homo sapiens_hsa052120.94957121
56TNF signaling pathway_Homo sapiens_hsa046680.94841926
57Autoimmune thyroid disease_Homo sapiens_hsa053200.91572309
58Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84296535
59Type I diabetes mellitus_Homo sapiens_hsa049400.80624512
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70751482
61Chronic myeloid leukemia_Homo sapiens_hsa052200.69440474
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.69313224
63VEGF signaling pathway_Homo sapiens_hsa043700.68406889
64Epstein-Barr virus infection_Homo sapiens_hsa051690.67875254
65Galactose metabolism_Homo sapiens_hsa000520.67568849
66Colorectal cancer_Homo sapiens_hsa052100.66562766
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65285462
68Sphingolipid signaling pathway_Homo sapiens_hsa040710.64640051
69Endocytosis_Homo sapiens_hsa041440.64591652
70Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64029696
71DNA replication_Homo sapiens_hsa030300.63820000
72Ribosome_Homo sapiens_hsa030100.62943714
73HTLV-I infection_Homo sapiens_hsa051660.58509230
74African trypanosomiasis_Homo sapiens_hsa051430.57215711
75Hepatitis C_Homo sapiens_hsa051600.56557137
76Ether lipid metabolism_Homo sapiens_hsa005650.56484628
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54330856
78Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49935756
79Arginine biosynthesis_Homo sapiens_hsa002200.49342099
80Vibrio cholerae infection_Homo sapiens_hsa051100.48287724
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48148394
82Viral carcinogenesis_Homo sapiens_hsa052030.46242707
83Non-small cell lung cancer_Homo sapiens_hsa052230.45880281
84Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45462050
85Renin-angiotensin system_Homo sapiens_hsa046140.45329460
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42312190
87Vitamin digestion and absorption_Homo sapiens_hsa049770.40095775
88Prolactin signaling pathway_Homo sapiens_hsa049170.38142299
89Prion diseases_Homo sapiens_hsa050200.37430662
90Arachidonic acid metabolism_Homo sapiens_hsa005900.35628050
91Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33253951
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32730822
93Inositol phosphate metabolism_Homo sapiens_hsa005620.32651139
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.32304561
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.32022824
96Type II diabetes mellitus_Homo sapiens_hsa049300.31164321
97Nitrogen metabolism_Homo sapiens_hsa009100.30902272
98N-Glycan biosynthesis_Homo sapiens_hsa005100.28990512
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28890894
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.27527517
101Sphingolipid metabolism_Homo sapiens_hsa006000.27404201
102Mineral absorption_Homo sapiens_hsa049780.25903189
103Rap1 signaling pathway_Homo sapiens_hsa040150.25801663
104MAPK signaling pathway_Homo sapiens_hsa040100.25607807
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25444921
106Renin secretion_Homo sapiens_hsa049240.25355381
107Protein export_Homo sapiens_hsa030600.25213934
108Morphine addiction_Homo sapiens_hsa050320.24930126
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23939619
110Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.23226371
111alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22736723
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20669465
113Choline metabolism in cancer_Homo sapiens_hsa052310.20601028
114p53 signaling pathway_Homo sapiens_hsa041150.20181134
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.19918750
116Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19596230
117Non-homologous end-joining_Homo sapiens_hsa034500.19228510
118Serotonergic synapse_Homo sapiens_hsa047260.19206998
119Amoebiasis_Homo sapiens_hsa051460.18077292
120Mismatch repair_Homo sapiens_hsa034300.16686625
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.15634253
122GnRH signaling pathway_Homo sapiens_hsa049120.15609112
123Linoleic acid metabolism_Homo sapiens_hsa005910.14856133
124Homologous recombination_Homo sapiens_hsa034400.14846807
125Base excision repair_Homo sapiens_hsa034100.14393021
126FoxO signaling pathway_Homo sapiens_hsa040680.13681078
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.12182967
128One carbon pool by folate_Homo sapiens_hsa006700.11344252
129Complement and coagulation cascades_Homo sapiens_hsa046100.10616193

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