FAM110A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.07278992
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.59959292
3negative regulation of cell killing (GO:0031342)4.59959292
4ribosomal small subunit assembly (GO:0000028)4.44811540
5pattern specification involved in kidney development (GO:0061004)4.38019157
6negative regulation of oligodendrocyte differentiation (GO:0048715)4.25080147
7response to peptidoglycan (GO:0032494)4.23792503
8negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.12538946
9neuron fate determination (GO:0048664)4.07916891
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.07287081
11viral transcription (GO:0019083)3.94183313
12leukocyte aggregation (GO:0070486)3.88354379
13modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.87438720
14modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.87438720
15positive regulation by organism of defense response of other organism involved in symbiotic interact3.87438720
16modulation by symbiont of host immune response (GO:0052553)3.87438720
17positive regulation by symbiont of host defense response (GO:0052509)3.87438720
18modulation by symbiont of host defense response (GO:0052031)3.87438720
19detection of bacterium (GO:0016045)3.87332944
20neutrophil activation (GO:0042119)3.86999201
21positive regulation of mast cell activation (GO:0033005)3.85531455
22immunoglobulin mediated immune response (GO:0016064)3.79844605
23translational termination (GO:0006415)3.72702482
24detection of other organism (GO:0098543)3.72636721
253-UTR-mediated mRNA stabilization (GO:0070935)3.71600705
26protein-DNA complex disassembly (GO:0032986)3.71259310
27nucleosome disassembly (GO:0006337)3.71259310
28radial glial cell differentiation (GO:0060019)3.62770851
29negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.59795435
30protein neddylation (GO:0045116)3.55274524
31leukocyte migration involved in inflammatory response (GO:0002523)3.54845191
32positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.54443342
33granulocyte activation (GO:0036230)3.52260484
34respiratory burst (GO:0045730)3.47599430
35nodal signaling pathway (GO:0038092)3.42953746
36regulation of mast cell degranulation (GO:0043304)3.41235492
37platelet dense granule organization (GO:0060155)3.38969789
38negative regulation of interleukin-12 production (GO:0032695)3.30463853
39translational elongation (GO:0006414)3.26294717
40mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.25642103
41positive regulation of Notch signaling pathway (GO:0045747)3.24230698
42neuronal stem cell maintenance (GO:0097150)3.23281464
43viral life cycle (GO:0019058)3.21775577
44positive regulation of mast cell degranulation (GO:0043306)3.20810301
45positive regulation of mast cell activation involved in immune response (GO:0033008)3.20810301
46NIK/NF-kappaB signaling (GO:0038061)3.19457829
47dopaminergic neuron differentiation (GO:0071542)3.16747548
48nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.16273202
49SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.15544189
50energy coupled proton transport, down electrochemical gradient (GO:0015985)3.14706932
51ATP synthesis coupled proton transport (GO:0015986)3.14706932
52lipoxygenase pathway (GO:0019372)3.12222378
53regulation of B cell receptor signaling pathway (GO:0050855)3.10111621
54negative regulation of T cell mediated immunity (GO:0002710)3.09961413
55positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.08193087
56cotranslational protein targeting to membrane (GO:0006613)3.03485991
57protein targeting to ER (GO:0045047)3.02885579
58regulation of mast cell activation involved in immune response (GO:0033006)3.01933356
59leukocyte degranulation (GO:0043299)3.00806047
60response to muramyl dipeptide (GO:0032495)2.99513355
61negative regulation of lymphocyte mediated immunity (GO:0002707)2.99469179
62regulation of mast cell activation (GO:0033003)2.98628566
63protein complex disassembly (GO:0043241)2.96624206
64pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.95842527
65pyrimidine dimer repair (GO:0006290)2.92623246
66myeloid cell activation involved in immune response (GO:0002275)2.91901916
67viral protein processing (GO:0019082)2.90918260
68cellular protein complex disassembly (GO:0043624)2.88321556
69negative regulation of RNA splicing (GO:0033119)2.87717530
70lymphoid progenitor cell differentiation (GO:0002320)2.87703455
71B cell mediated immunity (GO:0019724)2.86734243
72G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.85943811
73dosage compensation (GO:0007549)2.85445528
74negative regulation of erythrocyte differentiation (GO:0045647)2.85015746
75purinergic nucleotide receptor signaling pathway (GO:0035590)2.84510121
76deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.83425183
77activated T cell proliferation (GO:0050798)2.83092448
78translational initiation (GO:0006413)2.81932329
79establishment of protein localization to endoplasmic reticulum (GO:0072599)2.81368204
80pyrimidine nucleotide catabolic process (GO:0006244)2.78804986
81regulation of regulatory T cell differentiation (GO:0045589)2.77852072
82negative regulation of leukocyte mediated immunity (GO:0002704)2.77192109
83macrophage activation involved in immune response (GO:0002281)2.75744900
84protein localization to endoplasmic reticulum (GO:0070972)2.75619549
85mast cell activation (GO:0045576)2.75496922
86negative regulation of transcription by competitive promoter binding (GO:0010944)2.75240585
87segment specification (GO:0007379)2.73866011
88detection of external biotic stimulus (GO:0098581)2.73316915
89ribosomal small subunit biogenesis (GO:0042274)2.72171882
90macromolecular complex disassembly (GO:0032984)2.72028867
91phagosome maturation (GO:0090382)2.71253904
92regulation of myeloid leukocyte mediated immunity (GO:0002886)2.70933396
93response to UV-B (GO:0010224)2.69912928
94positive regulation of T cell mediated cytotoxicity (GO:0001916)2.69572177
95negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.69201081
96defense response to protozoan (GO:0042832)2.68905996
97maturation of SSU-rRNA (GO:0030490)2.66553994
98positive regulation of interleukin-8 secretion (GO:2000484)2.64242307
99response to host immune response (GO:0052572)2.63835529
100response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.63835529
101positive regulation of antigen processing and presentation (GO:0002579)2.62404839
102regulation of natural killer cell mediated immunity (GO:0002715)2.61195208
103regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.61195208
104positive regulation of B cell differentiation (GO:0045579)2.59978349
105astrocyte differentiation (GO:0048708)2.58877616
106regulation of T cell mediated cytotoxicity (GO:0001914)2.57800545
107negative regulation of telomere maintenance (GO:0032205)2.56641275
108paraxial mesoderm development (GO:0048339)2.55223636
109positive regulation of interleukin-17 production (GO:0032740)2.55143196
110nuclear-transcribed mRNA catabolic process (GO:0000956)2.53938751
111response to protozoan (GO:0001562)2.53650540
112virion assembly (GO:0019068)2.53376291
113regulation of antigen processing and presentation (GO:0002577)2.52331990
114autophagic vacuole fusion (GO:0000046)2.52189115
115cellular extravasation (GO:0045123)2.51670433
116regulation of leukocyte degranulation (GO:0043300)2.51256550
117negative regulation of phagocytosis (GO:0050765)2.50969249
118regulation of hypersensitivity (GO:0002883)2.50462279
119purinergic receptor signaling pathway (GO:0035587)2.47722948
120negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.47704551
121positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.46535433
122regulation of T cell tolerance induction (GO:0002664)2.46159109
123RNA destabilization (GO:0050779)2.44522850
124hair cell differentiation (GO:0035315)2.43508821
125mRNA catabolic process (GO:0006402)2.43196173
126protein retention in ER lumen (GO:0006621)2.42610230
127antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.41307461
128antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.41307461
129definitive hemopoiesis (GO:0060216)2.38033220
130positive regulation of erythrocyte differentiation (GO:0045648)2.36605595
131auditory receptor cell differentiation (GO:0042491)2.35471170
132regulation of fever generation (GO:0031620)2.32417473
133negative regulation of glycoprotein biosynthetic process (GO:0010561)2.31864572
134RNA catabolic process (GO:0006401)2.30226384
135venous blood vessel morphogenesis (GO:0048845)2.30060123
136positive regulation of BMP signaling pathway (GO:0030513)2.29758987
137maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.28140254
138sequestering of actin monomers (GO:0042989)2.27687303
139regulation of erythrocyte differentiation (GO:0045646)2.27261455
140embryonic hemopoiesis (GO:0035162)2.27244362
141tolerance induction (GO:0002507)2.26852778
142mitotic nuclear envelope reassembly (GO:0007084)2.26678991
143nuclear envelope reassembly (GO:0031468)2.26678991
144positive regulation of gamma-delta T cell activation (GO:0046645)2.22817185
145megakaryocyte development (GO:0035855)2.21505975
146positive regulation of receptor biosynthetic process (GO:0010870)2.20393245
147positive thymic T cell selection (GO:0045059)2.20158967
148antigen processing and presentation of endogenous antigen (GO:0019883)2.18938030
149spliceosomal complex assembly (GO:0000245)2.18908582
150cell migration involved in heart development (GO:0060973)2.18635625
151positive regulation by host of viral transcription (GO:0043923)2.17974313
152formation of translation preinitiation complex (GO:0001731)2.17802999
153activation of MAPKKK activity (GO:0000185)2.17574359
154granulocyte differentiation (GO:0030851)2.17400595
155negative regulation of mRNA processing (GO:0050686)2.17347742
156DNA integration (GO:0015074)2.16437122
157secretory granule organization (GO:0033363)2.16365449
158Arp2/3 complex-mediated actin nucleation (GO:0034314)2.16280837
159negative regulation of epidermal cell differentiation (GO:0045605)2.16087499
160negative regulation of Notch signaling pathway (GO:0045746)2.13989006
161positive regulation of histone deacetylation (GO:0031065)2.13048982
162regulation of gamma-delta T cell activation (GO:0046643)2.12821434
163transport of virus (GO:0046794)2.12244994
164intracellular transport of virus (GO:0075733)2.12244994
165multi-organism transport (GO:0044766)2.12244994
166multi-organism localization (GO:1902579)2.12244994
167multi-organism intracellular transport (GO:1902583)2.12244994
168mRNA stabilization (GO:0048255)2.10142342
169RNA stabilization (GO:0043489)2.10142342
170binding of sperm to zona pellucida (GO:0007339)2.09816699
171regulation of gamma-delta T cell differentiation (GO:0045586)2.09488087
172viral mRNA export from host cell nucleus (GO:0046784)2.08877149

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.78220248
2E2F7_22180533_ChIP-Seq_HELA_Human4.76615130
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.63923831
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.52460375
5STAT6_21828071_ChIP-Seq_BEAS2B_Human3.31320127
6MYC_22102868_ChIP-Seq_BL_Human3.28969790
7* FOXM1_23109430_ChIP-Seq_U2OS_Human3.21997976
8IRF8_21731497_ChIP-ChIP_J774_Mouse3.19815582
9SCL_19346495_ChIP-Seq_HPC-7_Human2.95517289
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.93838191
11TP63_19390658_ChIP-ChIP_HaCaT_Human2.83432466
12VDR_21846776_ChIP-Seq_THP-1_Human2.57026499
13IKZF1_21737484_ChIP-ChIP_HCT116_Human2.47915391
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.35240273
15* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.31423619
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.16054632
17STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.15717831
18LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.11623438
19MYC_18555785_ChIP-Seq_MESCs_Mouse2.10626913
20TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.08360648
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.02219862
22FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.01447679
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.98758354
24RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.96894647
25XRN2_22483619_ChIP-Seq_HELA_Human1.92329717
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91630279
27IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.85336632
28* TCF7_22412390_ChIP-Seq_EML_Mouse1.83521715
29MYC_19079543_ChIP-ChIP_MESCs_Mouse1.79398516
30* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.74942439
31MAF_26560356_Chip-Seq_TH1_Human1.71582944
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.71414364
33* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68627792
34VDR_24763502_ChIP-Seq_THP-1_Human1.68619808
35CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.68413777
36CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.67493862
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.67216348
38FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.66139839
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.66090839
40SPI1_23127762_ChIP-Seq_K562_Human1.63305692
41HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.59992037
42UTX_26944678_Chip-Seq_JUKART_Human1.58031241
43GABP_17652178_ChIP-ChIP_JURKAT_Human1.56146123
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.55263962
45E2F4_17652178_ChIP-ChIP_JURKAT_Human1.53393427
46BCOR_27268052_Chip-Seq_Bcells_Human1.51331451
47STAT4_19710469_ChIP-ChIP_TH1__Mouse1.50328231
48* RUNX1_22412390_ChIP-Seq_EML_Mouse1.49734541
49SA1_27219007_Chip-Seq_ERYTHROID_Human1.48866317
50PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.48584130
51CTCF_26484167_Chip-Seq_Bcells_Mouse1.47867032
52CIITA_25753668_ChIP-Seq_RAJI_Human1.46899420
53EZH2_22144423_ChIP-Seq_EOC_Human1.46365459
54MYB_26560356_Chip-Seq_TH2_Human1.46111815
55RARG_19884340_ChIP-ChIP_MEFs_Mouse1.46083902
56RUNX_20019798_ChIP-Seq_JUKART_Human1.45385193
57DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.44418736
58IRF8_27001747_Chip-Seq_BMDM_Mouse1.44286065
59TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.43392540
60ELK3_25401928_ChIP-Seq_HUVEC_Human1.41697800
61NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41345937
62P68_20966046_ChIP-Seq_HELA_Human1.40753179
63JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39405951
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38570860
65EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.37835955
66MYB_26560356_Chip-Seq_TH1_Human1.37417004
67IRF8_22096565_ChIP-ChIP_GC-B_Human1.37261002
68MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35666534
69KDM2B_26808549_Chip-Seq_DND41_Human1.34985179
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.33399142
71MYC_19030024_ChIP-ChIP_MESCs_Mouse1.31427131
72KDM2B_26808549_Chip-Seq_SUP-B15_Human1.31265536
73CTCF_27219007_Chip-Seq_ERYTHROID_Human1.31137220
74PU.1_20513432_ChIP-Seq_Bcells_Mouse1.30982199
75MAF_26560356_Chip-Seq_TH2_Human1.29744234
76* SPI1_23547873_ChIP-Seq_NB4_Human1.28671461
77GATA1_19941827_ChIP-Seq_MEL_Mouse1.28138137
78* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.25856033
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.25788644
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.25678449
81* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.25578621
82YY1_21170310_ChIP-Seq_MESCs_Mouse1.24019977
83E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23757727
84SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23515853
85TTF2_22483619_ChIP-Seq_HELA_Human1.22278740
86RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.22099123
87STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.21788453
88CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20808552
89BRD4_27068464_Chip-Seq_AML-cells_Mouse1.20698024
90FOXP3_21729870_ChIP-Seq_TREG_Human1.20485042
91E2F1_20622854_ChIP-Seq_HELA_Human1.19920652
92* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19464990
93CTCF_20526341_ChIP-Seq_ESCs_Human1.19370256
94KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.19270725
95P300_27268052_Chip-Seq_Bcells_Human1.18704445
96CTCF_21964334_ChIP-Seq_BJAB-B_Human1.18455518
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.18442251
98HIF1A_21447827_ChIP-Seq_MCF-7_Human1.18430995
99* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17965424
100MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.17212732
101CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16743943
102PHF8_20622854_ChIP-Seq_HELA_Human1.14177747
103E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.13956854
104PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13875819
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.13032498
106STAT1_20625510_ChIP-Seq_HELA_Human1.12686856
107NELFA_20434984_ChIP-Seq_ESCs_Mouse1.11659523
108CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11461973
109* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.11018996
110FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.10480015
111YY1_22570637_ChIP-Seq_MALME-3M_Human1.10370575
112* TET1_21451524_ChIP-Seq_MESCs_Mouse1.09330094
113* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.08802377
114ESR1_21235772_ChIP-Seq_MCF-7_Human1.07842961
115SA1_27219007_Chip-Seq_Bcells_Human1.07385303
116CTCF_21964334_Chip-Seq_Bcells_Human1.07050674
117VDR_23849224_ChIP-Seq_CD4+_Human1.06844105
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06643447
119VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.06074083
120SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.04212780
121GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03518524
122SOX2_18555785_ChIP-Seq_MESCs_Mouse1.03464884
123ETS1_20019798_ChIP-Seq_JURKAT_Human1.02980592
124LXR_22292898_ChIP-Seq_THP-1_Human1.01401177
125* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00962452
126ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00859076
127ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00731924
128SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99705093
129LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98318791
130RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.97123399
131GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96171778
132ZNF263_19887448_ChIP-Seq_K562_Human0.96030560
133SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95628065
134* DCP1A_22483619_ChIP-Seq_HELA_Human0.95518017
135SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.95388027
136PKCTHETA_26484144_Chip-Seq_BREAST_Human0.93810921
137ELF1_20517297_ChIP-Seq_JURKAT_Human0.92258291
138HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92248250
139EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.91855268
140IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.90316603
141ERG_20887958_ChIP-Seq_HPC-7_Mouse0.89278448
142EST1_17652178_ChIP-ChIP_JURKAT_Human0.88750295
143BCL6_27268052_Chip-Seq_Bcells_Human0.87963627
144NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.87946635
145STAT3_1855785_ChIP-Seq_MESCs_Mouse0.87816940

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology3.28608782
2MP0003693_abnormal_embryo_hatching2.60763438
3MP0008995_early_reproductive_senescence2.56143064
4MP0008007_abnormal_cellular_replicative2.50818943
5MP0002653_abnormal_ependyma_morphology2.45231872
6MP0000685_abnormal_immune_system2.40760963
7MP0009379_abnormal_foot_pigmentation2.37093645
8MP0003436_decreased_susceptibility_to2.31763707
9MP0009278_abnormal_bone_marrow2.22271650
10MP0002822_catalepsy2.19084263
11MP0008961_abnormal_basal_metabolism2.18538881
12MP0004808_abnormal_hematopoietic_stem2.10210726
13MP0005397_hematopoietic_system_phenotyp1.92594711
14MP0001545_abnormal_hematopoietic_system1.92594711
15MP0002396_abnormal_hematopoietic_system1.91307536
16MP0003866_abnormal_defecation1.87817282
17MP0002277_abnormal_respiratory_mucosa1.83675472
18MP0001835_abnormal_antigen_presentation1.82166762
19MP0003077_abnormal_cell_cycle1.79133353
20MP0009785_altered_susceptibility_to1.78711413
21MP0003787_abnormal_imprinting1.77546762
22MP0003303_peritoneal_inflammation1.77213385
23MP0006082_CNS_inflammation1.76841010
24MP0005174_abnormal_tail_pigmentation1.76093168
25MP0008004_abnormal_stomach_pH1.75820401
26MP0003786_premature_aging1.75419498
27MP0000490_abnormal_crypts_of1.70932070
28MP0003806_abnormal_nucleotide_metabolis1.69957304
29MP0005083_abnormal_biliary_tract1.65245063
30MP0004510_myositis1.65176273
31MP0005671_abnormal_response_to1.60435610
32MP0004381_abnormal_hair_follicle1.58801391
33MP0009764_decreased_sensitivity_to1.58259723
34MP0004947_skin_inflammation1.53968809
35MP0003763_abnormal_thymus_physiology1.53941722
36MP0004133_heterotaxia1.53464739
37MP0005076_abnormal_cell_differentiation1.53387495
38MP0001905_abnormal_dopamine_level1.52902165
39MP0010352_gastrointestinal_tract_polyps1.52498072
40MP0001800_abnormal_humoral_immune1.52356073
41MP0002398_abnormal_bone_marrow1.52310465
42MP0002452_abnormal_antigen_presenting1.50988214
43MP0005000_abnormal_immune_tolerance1.50752185
44MP0000858_altered_metastatic_potential1.48436316
45MP0000465_gastrointestinal_hemorrhage1.48010235
46MP0000343_altered_response_to1.45621802
47MP0008058_abnormal_DNA_repair1.42203691
48MP0002723_abnormal_immune_serum1.41516039
49MP0001881_abnormal_mammary_gland1.41393220
50MP0010094_abnormal_chromosome_stability1.40987954
51MP0001819_abnormal_immune_cell1.40977088
52MP0010155_abnormal_intestine_physiology1.40679643
53MP0002420_abnormal_adaptive_immunity1.40445628
54MP0001790_abnormal_immune_system1.39519214
55MP0005387_immune_system_phenotype1.39519214
56MP0001853_heart_inflammation1.39347370
57MP0000566_synostosis1.36502118
58MP0004957_abnormal_blastocyst_morpholog1.34090082
59MP0003183_abnormal_peptide_metabolism1.33831230
60MP0002877_abnormal_melanocyte_morpholog1.33648588
61MP0000689_abnormal_spleen_morphology1.33529651
62MP0000703_abnormal_thymus_morphology1.33515204
63MP0002132_abnormal_respiratory_system1.33357409
64MP0006054_spinal_hemorrhage1.33107747
65MP0005025_abnormal_response_to1.31962543
66MP0003315_abnormal_perineum_morphology1.31065837
67MP0002405_respiratory_system_inflammati1.30538175
68MP0001188_hyperpigmentation1.29061642
69MP0002722_abnormal_immune_system1.27663313
70MP0008469_abnormal_protein_level1.24792132
71MP0000716_abnormal_immune_system1.22981457
72MP0001663_abnormal_digestive_system1.21698020
73MP0005501_abnormal_skin_physiology1.20036984
74MP0008260_abnormal_autophagy1.19854319
75MP0003011_delayed_dark_adaptation1.18113013
76MP0002282_abnormal_trachea_morphology1.17582493
77MP0005310_abnormal_salivary_gland1.17154022
78MP0001270_distended_abdomen1.15327338
79MP0002148_abnormal_hypersensitivity_rea1.12920259
80MP0002429_abnormal_blood_cell1.11195771
81MP0003111_abnormal_nucleus_morphology1.10265353
82MP0002419_abnormal_innate_immunity1.09650043
83MP0002166_altered_tumor_susceptibility1.09195502
84MP0000350_abnormal_cell_proliferation1.08531090
85MP0005023_abnormal_wound_healing1.07996096
86MP0005084_abnormal_gallbladder_morpholo1.07443253
87MP0002933_joint_inflammation1.06565159
88MP0003878_abnormal_ear_physiology1.06154267
89MP0005377_hearing/vestibular/ear_phenot1.06154267
90MP0008932_abnormal_embryonic_tissue1.03827928
91MP0000049_abnormal_middle_ear1.03548875
92MP0001986_abnormal_taste_sensitivity1.03175519
93MP0001529_abnormal_vocalization1.01370385
94MP0005410_abnormal_fertilization0.99567821
95MP0005075_abnormal_melanosome_morpholog0.99452616
96MP0005058_abnormal_lysosome_morphology0.98515819
97MP0009765_abnormal_xenobiotic_induced0.98005104
98MP0006292_abnormal_olfactory_placode0.97447099
99MP0003566_abnormal_cell_adhesion0.96988657
100MP0003638_abnormal_response/metabolism_0.94642157
101MP0003448_altered_tumor_morphology0.93917551
102MP0000313_abnormal_cell_death0.93697353
103MP0006276_abnormal_autonomic_nervous0.92933300
104MP0003191_abnormal_cellular_cholesterol0.92456487
105MP0002751_abnormal_autonomic_nervous0.91830886
106MP0001873_stomach_inflammation0.91759822
107MP0000569_abnormal_digit_pigmentation0.91672894
108MP0002019_abnormal_tumor_incidence0.91546030
109MP0001968_abnormal_touch/_nociception0.91138186
110MP0002234_abnormal_pharynx_morphology0.90494238
111MP0009333_abnormal_splenocyte_physiolog0.90333665
112MP0001845_abnormal_inflammatory_respons0.87093877
113MP0001851_eye_inflammation0.84504273
114MP0003091_abnormal_cell_migration0.83911382
115MP0001533_abnormal_skeleton_physiology0.83756980
116MP0002796_impaired_skin_barrier0.82893448
117MP0003941_abnormal_skin_development0.81275990
118MP0003300_gastrointestinal_ulcer0.80816434
119MP0005167_abnormal_blood-brain_barrier0.80337355
120MP0005464_abnormal_platelet_physiology0.79477764
121MP0005381_digestive/alimentary_phenotyp0.78348313
122MP0003453_abnormal_keratinocyte_physiol0.78348201
123MP0002249_abnormal_larynx_morphology0.78291621
124MP0001216_abnormal_epidermal_layer0.77710385
125MP0003828_pulmonary_edema0.77601598
126MP0005390_skeleton_phenotype0.77464703
127MP0005367_renal/urinary_system_phenotyp0.75838660
128MP0000516_abnormal_urinary_system0.75838660
129MP0005220_abnormal_exocrine_pancreas0.75682888
130MP0004782_abnormal_surfactant_physiolog0.75393020
131MP0003172_abnormal_lysosome_physiology0.74469134
132MP0008789_abnormal_olfactory_epithelium0.72486875
133MP0003724_increased_susceptibility_to0.71973518
134MP0004264_abnormal_extraembryonic_tissu0.71962966
135MP0002909_abnormal_adrenal_gland0.71557034
136MP0001919_abnormal_reproductive_system0.71516029
137MP0002098_abnormal_vibrissa_morphology0.71390797
138MP0004142_abnormal_muscle_tone0.69451411
139MP0009763_increased_sensitivity_to0.68108312
140MP0004883_abnormal_blood_vessel0.67596125
141MP0008874_decreased_physiological_sensi0.63496592
142MP0006035_abnormal_mitochondrial_morpho0.62619659
143MP0005394_taste/olfaction_phenotype0.61127622
144MP0005499_abnormal_olfactory_system0.61127622
145MP0002254_reproductive_system_inflammat0.60923579
146MP0002102_abnormal_ear_morphology0.60715889
147MP0002736_abnormal_nociception_after0.60069984
148MP0006036_abnormal_mitochondrial_physio0.58930777

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)4.51660366
2Abnormality of macrophages (HP:0004311)4.02936963
3Elevated erythrocyte sedimentation rate (HP:0003565)4.02867294
4Myositis (HP:0100614)3.98822547
5Purpura (HP:0000979)3.81562870
6Chronic obstructive pulmonary disease (HP:0006510)3.72866033
7Obstructive lung disease (HP:0006536)3.72866033
8Increased IgM level (HP:0003496)3.46412352
9Optic neuritis (HP:0100653)3.44350037
10Retrobulbar optic neuritis (HP:0100654)3.44350037
11Orchitis (HP:0100796)3.40369383
12Nasal polyposis (HP:0100582)3.35332173
13Large eyes (HP:0001090)3.33033872
14Abnormality of the intervertebral disk (HP:0005108)3.32536010
15Abnormality of the nasal mucosa (HP:0000433)3.24756370
16Increased density of long bones (HP:0006392)3.20271266
17Abnormal number of erythroid precursors (HP:0012131)3.19053225
18Prominent metopic ridge (HP:0005487)3.18618295
19Overlapping toe (HP:0001845)3.11054662
20Nonprogressive disorder (HP:0003680)3.11011529
21Degeneration of anterior horn cells (HP:0002398)3.10678225
22Abnormality of the anterior horn cell (HP:0006802)3.10678225
23Abnormality of cells of the erythroid lineage (HP:0012130)3.07747198
24Epistaxis (HP:0000421)3.06683252
25Encephalitis (HP:0002383)3.04719772
26Urticaria (HP:0001025)3.03042539
27Thrombocytosis (HP:0001894)3.02365135
28Renal Fanconi syndrome (HP:0001994)3.02009696
29Pustule (HP:0200039)2.93018743
30Recurrent skin infections (HP:0001581)2.90957799
31Reticulocytopenia (HP:0001896)2.86389462
32Abnormality of the heme biosynthetic pathway (HP:0010472)2.84511904
33Abnormality of the metopic suture (HP:0005556)2.77630238
343-Methylglutaconic aciduria (HP:0003535)2.73726011
35Meningitis (HP:0001287)2.70335175
36Persistence of primary teeth (HP:0006335)2.68789198
37Abnormal platelet volume (HP:0011876)2.67156357
38Failure to thrive in infancy (HP:0001531)2.66443596
39Spontaneous hematomas (HP:0007420)2.65484212
40Panhypogammaglobulinemia (HP:0003139)2.65347828
41Cortical dysplasia (HP:0002539)2.63618184
4211 pairs of ribs (HP:0000878)2.63266187
43Rib fusion (HP:0000902)2.63233697
44Menorrhagia (HP:0000132)2.62681821
45Abnormal delayed hypersensitivity skin test (HP:0002963)2.60683511
46Hypochromic anemia (HP:0001931)2.58143654
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.56457005
48Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.56457005
49Recurrent cutaneous fungal infections (HP:0011370)2.56086234
50Chronic mucocutaneous candidiasis (HP:0002728)2.56086234
51Pallor (HP:0000980)2.52258439
52Generalized aminoaciduria (HP:0002909)2.51654933
53Hypochromic microcytic anemia (HP:0004840)2.50410642
54Chronic otitis media (HP:0000389)2.49765102
55Hyperacusis (HP:0010780)2.49072386
56Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.47277547
57Gingival bleeding (HP:0000225)2.46843917
58Recurrent gram-negative bacterial infections (HP:0005420)2.46743117
59Broad face (HP:0000283)2.46508308
60Mitochondrial inheritance (HP:0001427)2.43224567
61IgM deficiency (HP:0002850)2.39453791
62Exertional dyspnea (HP:0002875)2.39317032
63Interstitial pulmonary disease (HP:0006530)2.37937657
64Lipid accumulation in hepatocytes (HP:0006561)2.37417329
65Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.37086382
66Increased muscle lipid content (HP:0009058)2.35542087
67Muscle fiber atrophy (HP:0100295)2.35481051
68Increased hepatocellular lipid droplets (HP:0006565)2.34184967
69Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.31733861
70Hypergammaglobulinemia (HP:0010702)2.27661089
71Anorexia (HP:0002039)2.26923106
72Increased intramyocellular lipid droplets (HP:0012240)2.26892638
73Abnormality of the fingertips (HP:0001211)2.26640217
74Reduced antithrombin III activity (HP:0001976)2.26239735
75Absent rod-and cone-mediated responses on ERG (HP:0007688)2.25791980
76Episodic fever (HP:0001954)2.24637894
77Microcytic anemia (HP:0001935)2.23693994
78Abnormality of the radial head (HP:0003995)2.21250507
79Patchy hypopigmentation of hair (HP:0011365)2.20328718
80Increased serum ferritin (HP:0003281)2.20058792
81Heterochromia iridis (HP:0001100)2.18042478
82Agnosia (HP:0010524)2.17947950
83Acute necrotizing encephalopathy (HP:0006965)2.16952200
84Respiratory difficulties (HP:0002880)2.15588436
85Eczematoid dermatitis (HP:0000976)2.14652487
86Keratoconjunctivitis sicca (HP:0001097)2.14277584
87Hypertensive crisis (HP:0100735)2.13796922
88Bicuspid aortic valve (HP:0001647)2.11380208
89Increased mean platelet volume (HP:0011877)2.10522022
90Abnormality of iron homeostasis (HP:0011031)2.09245411
91Pendular nystagmus (HP:0012043)2.09224432
92Abnormal mitochondria in muscle tissue (HP:0008316)2.08640584
93Hepatocellular necrosis (HP:0001404)2.02782923
94Macrocytic anemia (HP:0001972)2.02435367
95Hepatosplenomegaly (HP:0001433)2.00609103
96Rectal prolapse (HP:0002035)1.99951618
97Patellar aplasia (HP:0006443)1.99016853
98Arterial thrombosis (HP:0004420)1.98663185
99Abnormality of renal resorption (HP:0011038)1.98049136
100Amaurosis fugax (HP:0100576)1.97984042
101Down-sloping shoulders (HP:0200021)1.97568672
102Parakeratosis (HP:0001036)1.96598365
103Hepatic necrosis (HP:0002605)1.94995723
104Glomerulopathy (HP:0100820)1.94601027
105Abnormality of lateral ventricle (HP:0030047)1.93625647
106Polyphagia (HP:0002591)1.92734193
107Keratoconjunctivitis (HP:0001096)1.91967735
108Congenital ichthyosiform erythroderma (HP:0007431)1.90225892
109Aplastic anemia (HP:0001915)1.88786922
110Vasculitis (HP:0002633)1.88466237
111Chronic sinusitis (HP:0011109)1.86255005
112Chest pain (HP:0100749)1.86083671
113Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.86019601
114Increased CSF lactate (HP:0002490)1.84926060
115Optic nerve coloboma (HP:0000588)1.84272435
116Gastrointestinal infarctions (HP:0005244)1.83207158
117Abnormality of transition element cation homeostasis (HP:0011030)1.82216825
118Broad alveolar ridges (HP:0000187)1.81975231
119IgG deficiency (HP:0004315)1.81564219
120Anomalous pulmonary venous return (HP:0010772)1.81427441
121Seborrheic dermatitis (HP:0001051)1.81247356
122Abnormal hemoglobin (HP:0011902)1.81051214
123Abnormality of the aortic arch (HP:0012303)1.80996199
124Self-mutilation (HP:0000742)1.80224318
125Aplasia/Hypoplasia of the patella (HP:0006498)1.79453724
126Ridged nail (HP:0001807)1.77956317
127Gastrointestinal inflammation (HP:0004386)1.77527578
128Increased IgE level (HP:0003212)1.77344126
129Long eyelashes (HP:0000527)1.77343920
130Spinal muscular atrophy (HP:0007269)1.76829996
131Microretrognathia (HP:0000308)1.76631614
132Agammaglobulinemia (HP:0004432)1.76627451
133Thyroiditis (HP:0100646)1.75528685
134Congenital glaucoma (HP:0001087)1.75109804
135Hemivertebrae (HP:0002937)1.74354090
136Recurrent bacterial skin infections (HP:0005406)1.73998217
137Anterior segment dysgenesis (HP:0007700)1.72865577
138Cellulitis (HP:0100658)1.72603460
139Hemoptysis (HP:0002105)1.71344764
140Pulmonary infiltrates (HP:0002113)1.70772246
141Petechiae (HP:0000967)1.70500449
142Dislocated radial head (HP:0003083)1.70310641
143Recurrent bronchitis (HP:0002837)1.69437429
144Type I transferrin isoform profile (HP:0003642)1.69387177
145Broad palm (HP:0001169)1.67239554
146Growth hormone excess (HP:0000845)1.67215042
147Short philtrum (HP:0000322)1.67212561
148Abnormal number of incisors (HP:0011064)1.67100572
149White forelock (HP:0002211)1.66777283
150Abnormality of the pericardium (HP:0001697)1.65741892
151Medulloblastoma (HP:0002885)1.64914368
152Abnormal sex determination (HP:0012244)1.64508916
153Sex reversal (HP:0012245)1.64508916
154Recurrent fungal infections (HP:0002841)1.63411716
155Bilateral microphthalmos (HP:0007633)1.63239146
156Aseptic necrosis (HP:0010885)1.62945405
157Recurrent abscess formation (HP:0002722)1.61784170
158Prolonged bleeding time (HP:0003010)1.59677855
159Leukocytosis (HP:0001974)1.57625492
160Long palpebral fissure (HP:0000637)1.54776241
161Mediastinal lymphadenopathy (HP:0100721)1.54324738
162Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.53794131
163Abnormal protein N-linked glycosylation (HP:0012347)1.53794131
164Abnormal protein glycosylation (HP:0012346)1.53794131
165Abnormal glycosylation (HP:0012345)1.53794131
166Oral leukoplakia (HP:0002745)1.52887487
167Gangrene (HP:0100758)1.52424881
168Abnormality of eosinophils (HP:0001879)1.52303034
169Bronchitis (HP:0012387)1.52220518
170Erythema (HP:0010783)1.51690139
171Type 2 muscle fiber atrophy (HP:0003554)1.50438115

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.53265212
2EEF2K2.91226870
3GRK62.86028813
4SIK32.83878180
5DYRK32.83742860
6EPHA32.57451800
7PIM22.49621413
8ACVR1B2.36832680
9TAOK12.22328489
10ADRBK22.19220075
11TESK12.16622501
12EPHB22.16230690
13IRAK22.15902864
14RPS6KA42.14192332
15MAPKAPK32.10785213
16TNK22.03038664
17TGFBR11.95233473
18MAP3K101.90550954
19BCKDK1.89174360
20TBK11.88414065
21MAP2K71.87854965
22CSK1.77888603
23MAP4K11.77487418
24FES1.77004472
25TRIB31.74557216
26ZAP701.73443914
27CHUK1.71226268
28MAP3K141.65041058
29DYRK1B1.61341611
30BLK1.60902243
31BTK1.60330837
32MAP4K21.59608525
33TGFBR21.57932677
34IRAK41.49226008
35BRD41.48722349
36PAK41.44426010
37TESK21.44369200
38FGR1.43848227
39KIT1.41651671
40IKBKB1.36536113
41SIK21.35978435
42MAP2K41.34745042
43ERN11.33418303
44MAP2K21.32808118
45MAP3K61.26431728
46MAPK151.23151972
47PRKD21.23006368
48RPS6KB21.22449075
49STK101.21751415
50TAOK21.19738091
51TXK1.19233512
52SRPK11.18542062
53BUB11.18491787
54PASK1.17904918
55VRK11.15750455
56LYN1.14637963
57IKBKE1.13432359
58CDK191.13005357
59MKNK11.12588692
60PIM11.10929952
61EPHB11.09584754
62VRK21.09382018
63RPS6KA11.06629765
64NME21.06628030
65CDK121.05051219
66NME11.03095047
67GRK10.96720979
68MARK30.95825354
69RPS6KA20.95250569
70SIK10.92690901
71CDK80.90396913
72LCK0.89923662
73RPS6KA60.89255690
74FGFR40.88960316
75CSF1R0.88879733
76MAPKAPK20.87804501
77FGFR30.87309809
78RPS6KC10.87081373
79RPS6KL10.87081373
80MAP3K130.86191790
81MAP2K30.85787105
82JAK30.83218811
83RPS6KA50.83150430
84TYK20.82885008
85STK160.81461348
86MAP3K10.81345603
87TSSK60.80675116
88NEK20.80121260
89ERBB20.80048014
90MAP3K120.77807530
91AURKB0.76372040
92KSR10.73081347
93MATK0.72861520
94MAP3K110.72573343
95TEC0.71326463
96ATR0.70699177
97MELK0.70472808
98CDK60.68921165
99LRRK20.67745362
100MARK20.63534789
101MAPK110.62392757
102ICK0.61977377
103SYK0.61854689
104TIE10.61614670
105TLK10.61279209
106CDK70.61162124
107GRK70.61044225
108PKN20.60413560
109MAPK130.59293548
110DYRK20.59139318
111MAP3K40.58606173
112EIF2AK10.58438053
113YES10.57882539
114PRKCQ0.57864081
115MAP3K30.56575522
116EPHA20.56465406
117ILK0.56099356
118BRSK10.55897342
119PTK60.55789983
120MAP3K50.54518069
121MAP2K60.54407467
122BMX0.53705544
123ABL20.53633372
124JAK20.52783632
125ERBB30.52527369
126EIF2AK20.51829573
127PRKG20.51563053
128HCK0.51537735
129ITK0.51374600
130HIPK20.50714312
131NLK0.50112060
132AURKA0.48673310
133PRKCD0.48258886
134PINK10.47690818
135MAPK40.47516857
136FYN0.47450241
137ADRBK10.47108684
138ARAF0.45660022
139MAPK70.45234340
140IRAK30.43865964
141TAOK30.42621483
142IRAK10.41676252
143KDR0.41566155
144MINK10.41394971
145GRK50.37933917
146PRKCZ0.32335042

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.06276545
2Ribosome_Homo sapiens_hsa030102.92746904
3Notch signaling pathway_Homo sapiens_hsa043302.65140579
4Parkinsons disease_Homo sapiens_hsa050122.63539766
5Spliceosome_Homo sapiens_hsa030402.51992030
6Leishmaniasis_Homo sapiens_hsa051402.18891803
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.15355107
8Autoimmune thyroid disease_Homo sapiens_hsa053202.12727296
9Collecting duct acid secretion_Homo sapiens_hsa049662.01745434
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93348608
11DNA replication_Homo sapiens_hsa030301.85194673
12Herpes simplex infection_Homo sapiens_hsa051681.82994132
13Measles_Homo sapiens_hsa051621.80955237
14Cell cycle_Homo sapiens_hsa041101.79891090
15Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.79346377
16Asthma_Homo sapiens_hsa053101.74818876
17Osteoclast differentiation_Homo sapiens_hsa043801.72328326
18Base excision repair_Homo sapiens_hsa034101.71041821
19Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.70278940
20Staphylococcus aureus infection_Homo sapiens_hsa051501.67119647
21Type I diabetes mellitus_Homo sapiens_hsa049401.66917722
22Epstein-Barr virus infection_Homo sapiens_hsa051691.60851982
23Tuberculosis_Homo sapiens_hsa051521.57590214
24Chronic myeloid leukemia_Homo sapiens_hsa052201.57492639
25Legionellosis_Homo sapiens_hsa051341.56666564
26Alzheimers disease_Homo sapiens_hsa050101.56188280
27Shigellosis_Homo sapiens_hsa051311.54995550
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.53652274
29Rheumatoid arthritis_Homo sapiens_hsa053231.53410579
30Phagosome_Homo sapiens_hsa041451.49679080
31Antigen processing and presentation_Homo sapiens_hsa046121.48605313
32Toll-like receptor signaling pathway_Homo sapiens_hsa046201.48522374
33TNF signaling pathway_Homo sapiens_hsa046681.47623141
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.45913087
35Chemokine signaling pathway_Homo sapiens_hsa040621.45644308
36p53 signaling pathway_Homo sapiens_hsa041151.44269169
37Huntingtons disease_Homo sapiens_hsa050161.43376361
38Acute myeloid leukemia_Homo sapiens_hsa052211.41981739
39RNA polymerase_Homo sapiens_hsa030201.38027317
40B cell receptor signaling pathway_Homo sapiens_hsa046621.37852624
41Primary immunodeficiency_Homo sapiens_hsa053401.37121585
42Proteasome_Homo sapiens_hsa030501.35161739
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.32005373
44HTLV-I infection_Homo sapiens_hsa051661.31894690
45Influenza A_Homo sapiens_hsa051641.31797443
46Pyrimidine metabolism_Homo sapiens_hsa002401.29513924
47Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.28536034
48Fanconi anemia pathway_Homo sapiens_hsa034601.27191713
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.26334541
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.26221518
51Apoptosis_Homo sapiens_hsa042101.26220199
52Prolactin signaling pathway_Homo sapiens_hsa049171.25014535
53Jak-STAT signaling pathway_Homo sapiens_hsa046301.23546712
54Mismatch repair_Homo sapiens_hsa034301.23314388
55T cell receptor signaling pathway_Homo sapiens_hsa046601.22690165
56Small cell lung cancer_Homo sapiens_hsa052221.22678753
57Hepatitis B_Homo sapiens_hsa051611.22625998
58Regulation of autophagy_Homo sapiens_hsa041401.19601212
59Intestinal immune network for IgA production_Homo sapiens_hsa046721.18124981
60Toxoplasmosis_Homo sapiens_hsa051451.17975807
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14659652
62Colorectal cancer_Homo sapiens_hsa052101.13114788
63RNA transport_Homo sapiens_hsa030131.11515359
64Nucleotide excision repair_Homo sapiens_hsa034201.09212660
65Hematopoietic cell lineage_Homo sapiens_hsa046401.05790941
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.02649343
67Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99188751
68Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.98154168
69MicroRNAs in cancer_Homo sapiens_hsa052060.96869232
70Bladder cancer_Homo sapiens_hsa052190.96405974
71Pertussis_Homo sapiens_hsa051330.96393249
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.95153557
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93341093
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92709607
75Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.92318455
76Leukocyte transendothelial migration_Homo sapiens_hsa046700.91547497
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.91257914
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86829487
79mRNA surveillance pathway_Homo sapiens_hsa030150.86610071
80Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84825829
81RNA degradation_Homo sapiens_hsa030180.82432947
82Circadian rhythm_Homo sapiens_hsa047100.81192959
83Viral carcinogenesis_Homo sapiens_hsa052030.79814278
84Homologous recombination_Homo sapiens_hsa034400.79063682
85Graft-versus-host disease_Homo sapiens_hsa053320.78136843
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76758127
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76661537
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.76498879
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.76359091
90Maturity onset diabetes of the young_Homo sapiens_hsa049500.75294181
91Cardiac muscle contraction_Homo sapiens_hsa042600.74311794
92Salmonella infection_Homo sapiens_hsa051320.74302750
93Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73166232
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72421515
95Pancreatic cancer_Homo sapiens_hsa052120.72106339
96Lysosome_Homo sapiens_hsa041420.72017173
97Malaria_Homo sapiens_hsa051440.70932584
98Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69080382
99TGF-beta signaling pathway_Homo sapiens_hsa043500.68801797
100Endocytosis_Homo sapiens_hsa041440.67918304
101Pathways in cancer_Homo sapiens_hsa052000.67451173
102N-Glycan biosynthesis_Homo sapiens_hsa005100.67000249
103Arachidonic acid metabolism_Homo sapiens_hsa005900.66912055
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65765228
105Basal transcription factors_Homo sapiens_hsa030220.65458903
106Hepatitis C_Homo sapiens_hsa051600.65158653
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64395189
108Basal cell carcinoma_Homo sapiens_hsa052170.63713436
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63705911
110Viral myocarditis_Homo sapiens_hsa054160.62699930
111Allograft rejection_Homo sapiens_hsa053300.62512897
112Thyroid cancer_Homo sapiens_hsa052160.62053750
113Systemic lupus erythematosus_Homo sapiens_hsa053220.58896131
114Sulfur relay system_Homo sapiens_hsa041220.58534004
115FoxO signaling pathway_Homo sapiens_hsa040680.58440295
116Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.58279551
117Hippo signaling pathway_Homo sapiens_hsa043900.57753148
118Non-homologous end-joining_Homo sapiens_hsa034500.55964861
119Platelet activation_Homo sapiens_hsa046110.54777753
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52978604
121Phototransduction_Homo sapiens_hsa047440.51364493
122Proteoglycans in cancer_Homo sapiens_hsa052050.50806001
123Non-small cell lung cancer_Homo sapiens_hsa052230.49989302
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49413144
125Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48088548
126Endometrial cancer_Homo sapiens_hsa052130.47710002
127Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.47532429
128Other glycan degradation_Homo sapiens_hsa005110.47231646
129Linoleic acid metabolism_Homo sapiens_hsa005910.46420191
130Renal cell carcinoma_Homo sapiens_hsa052110.46035115
131VEGF signaling pathway_Homo sapiens_hsa043700.45434864
132Synaptic vesicle cycle_Homo sapiens_hsa047210.45047286
133HIF-1 signaling pathway_Homo sapiens_hsa040660.44194632
134Vibrio cholerae infection_Homo sapiens_hsa051100.43600108
135Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42562820
136African trypanosomiasis_Homo sapiens_hsa051430.41953974
137Alcoholism_Homo sapiens_hsa050340.41747802
138Olfactory transduction_Homo sapiens_hsa047400.41543570
139Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36607251
140Sphingolipid signaling pathway_Homo sapiens_hsa040710.36499059
141Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.33273423
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31998014
143Serotonergic synapse_Homo sapiens_hsa047260.29836164
144Glycerophospholipid metabolism_Homo sapiens_hsa005640.29225450

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