Rank | Gene Set | Z-score |
---|---|---|
1 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.48567936 |
2 | vocalization behavior (GO:0071625) | 5.26129649 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.05872741 |
4 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.98189899 |
5 | synaptic vesicle exocytosis (GO:0016079) | 4.89973183 |
6 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.82160523 |
7 | neuron cell-cell adhesion (GO:0007158) | 4.82147387 |
8 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.76992638 |
9 | protein localization to synapse (GO:0035418) | 4.64631979 |
10 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.60487970 |
11 | nucleobase catabolic process (GO:0046113) | 4.59421311 |
12 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.54976367 |
13 | synaptic vesicle maturation (GO:0016188) | 4.44606465 |
14 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.41064243 |
15 | glutamate secretion (GO:0014047) | 4.37231031 |
16 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.36022077 |
17 | regulation of synapse structural plasticity (GO:0051823) | 4.26313832 |
18 | postsynaptic membrane organization (GO:0001941) | 4.26095859 |
19 | locomotory exploration behavior (GO:0035641) | 4.18586525 |
20 | glutamate receptor signaling pathway (GO:0007215) | 4.11066777 |
21 | limb bud formation (GO:0060174) | 4.08721116 |
22 | synaptic transmission, glutamatergic (GO:0035249) | 4.01967606 |
23 | positive regulation of synapse maturation (GO:0090129) | 4.00730934 |
24 | regulation of synaptic vesicle transport (GO:1902803) | 3.97480180 |
25 | exploration behavior (GO:0035640) | 3.90925488 |
26 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.90103660 |
27 | neuron-neuron synaptic transmission (GO:0007270) | 3.88868154 |
28 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.84775579 |
29 | neuron recognition (GO:0008038) | 3.84071811 |
30 | presynaptic membrane assembly (GO:0097105) | 3.81945968 |
31 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.80833063 |
32 | synaptic vesicle endocytosis (GO:0048488) | 3.77757181 |
33 | neurotransmitter secretion (GO:0007269) | 3.76194363 |
34 | neuronal action potential propagation (GO:0019227) | 3.73158497 |
35 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.68548310 |
36 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.63812125 |
37 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.62827366 |
38 | layer formation in cerebral cortex (GO:0021819) | 3.58743799 |
39 | cell migration in hindbrain (GO:0021535) | 3.57639055 |
40 | presynaptic membrane organization (GO:0097090) | 3.55507294 |
41 | dendritic spine morphogenesis (GO:0060997) | 3.53844436 |
42 | response to pheromone (GO:0019236) | 3.53414472 |
43 | axonal fasciculation (GO:0007413) | 3.52664263 |
44 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.52269833 |
45 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.50711956 |
46 | behavioral fear response (GO:0001662) | 3.44784696 |
47 | behavioral defense response (GO:0002209) | 3.44784696 |
48 | positive regulation of membrane potential (GO:0045838) | 3.42935868 |
49 | long-term memory (GO:0007616) | 3.39457000 |
50 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.37410543 |
51 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.33156856 |
52 | regulation of postsynaptic membrane potential (GO:0060078) | 3.31940635 |
53 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.31494598 |
54 | glial cell proliferation (GO:0014009) | 3.25113707 |
55 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.24462218 |
56 | regulation of synapse maturation (GO:0090128) | 3.23282134 |
57 | glycosphingolipid biosynthetic process (GO:0006688) | 3.23152960 |
58 | dendrite morphogenesis (GO:0048813) | 3.23144989 |
59 | C4-dicarboxylate transport (GO:0015740) | 3.22170538 |
60 | positive regulation of mitochondrial fission (GO:0090141) | 3.22097751 |
61 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.22034340 |
62 | positive regulation of synapse assembly (GO:0051965) | 3.20870741 |
63 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.18900860 |
64 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.18759603 |
65 | fear response (GO:0042596) | 3.18211315 |
66 | dopamine receptor signaling pathway (GO:0007212) | 3.17070018 |
67 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.16229015 |
68 | prepulse inhibition (GO:0060134) | 3.15540672 |
69 | activation of protein kinase A activity (GO:0034199) | 3.15353395 |
70 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.14569754 |
71 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.13335149 |
72 | response to histamine (GO:0034776) | 3.12804484 |
73 | regulation of synaptic plasticity (GO:0048167) | 3.10856103 |
74 | synapse assembly (GO:0007416) | 3.10849960 |
75 | innervation (GO:0060384) | 3.09611102 |
76 | protein-cofactor linkage (GO:0018065) | 3.08466268 |
77 | long-term synaptic potentiation (GO:0060291) | 3.07870330 |
78 | sympathetic nervous system development (GO:0048485) | 3.06890608 |
79 | proline transport (GO:0015824) | 3.05389516 |
80 | regulation of neurotransmitter secretion (GO:0046928) | 3.04661507 |
81 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.03431630 |
82 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.02991958 |
83 | striatum development (GO:0021756) | 3.02962230 |
84 | transmission of nerve impulse (GO:0019226) | 3.01532082 |
85 | neural tube formation (GO:0001841) | 3.00455404 |
86 | mechanosensory behavior (GO:0007638) | 2.98680056 |
87 | auditory behavior (GO:0031223) | 2.98007591 |
88 | gamma-aminobutyric acid transport (GO:0015812) | 2.96462484 |
89 | response to auditory stimulus (GO:0010996) | 2.96372271 |
90 | learning (GO:0007612) | 2.96357108 |
91 | cell communication by electrical coupling (GO:0010644) | 2.95813110 |
92 | neurotransmitter transport (GO:0006836) | 2.95764321 |
93 | behavioral response to nicotine (GO:0035095) | 2.95500282 |
94 | negative regulation of dendrite development (GO:2000171) | 2.95281197 |
95 | membrane depolarization during action potential (GO:0086010) | 2.94903590 |
96 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.92677790 |
97 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.92634880 |
98 | regulation of vesicle fusion (GO:0031338) | 2.91260073 |
99 | regulation of neurotransmitter transport (GO:0051588) | 2.90546951 |
100 | detection of calcium ion (GO:0005513) | 2.89179796 |
101 | membrane depolarization (GO:0051899) | 2.88794251 |
102 | inositol phosphate catabolic process (GO:0071545) | 2.88528667 |
103 | cornea development in camera-type eye (GO:0061303) | 2.85708691 |
104 | dendritic spine organization (GO:0097061) | 2.85184395 |
105 | startle response (GO:0001964) | 2.82613130 |
106 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.81993815 |
107 | synaptic transmission (GO:0007268) | 2.81561836 |
108 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.81457204 |
109 | olfactory bulb development (GO:0021772) | 2.81352357 |
110 | dendrite development (GO:0016358) | 2.80446820 |
111 | positive regulation of dendritic spine development (GO:0060999) | 2.79647619 |
112 | negative regulation of microtubule polymerization (GO:0031115) | 2.79426310 |
113 | regulation of synapse organization (GO:0050807) | 2.79345558 |
114 | synaptic transmission, dopaminergic (GO:0001963) | 2.79203528 |
115 | female mating behavior (GO:0060180) | 2.79040756 |
116 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.78071448 |
117 | regulation of synapse assembly (GO:0051963) | 2.77839071 |
118 | establishment of synaptic vesicle localization (GO:0097480) | 2.77475899 |
119 | protein polyglutamylation (GO:0018095) | 2.75957170 |
120 | reflex (GO:0060004) | 2.75352821 |
121 | nonmotile primary cilium assembly (GO:0035058) | 2.72346700 |
122 | somite development (GO:0061053) | 2.72136910 |
123 | retinal ganglion cell axon guidance (GO:0031290) | 2.71495605 |
124 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.71413600 |
125 | cardiac ventricle formation (GO:0003211) | 2.71386163 |
126 | hippocampus development (GO:0021766) | 2.71005093 |
127 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.70955123 |
128 | spinal cord development (GO:0021510) | 2.69198271 |
129 | positive regulation of amino acid transport (GO:0051957) | 2.68853497 |
130 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.66494576 |
131 | establishment of mitochondrion localization (GO:0051654) | 2.66094521 |
132 | cellular ketone body metabolic process (GO:0046950) | 2.64571926 |
133 | protein localization to cilium (GO:0061512) | 2.63108428 |
134 | regulation of cilium movement (GO:0003352) | 2.60807583 |
135 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.57433964 |
136 | head development (GO:0060322) | 2.56038367 |
137 | negative regulation of axon extension (GO:0030517) | 2.53335045 |
138 | regulation of respiratory system process (GO:0044065) | 2.52909232 |
139 | regulation of timing of cell differentiation (GO:0048505) | 2.52877366 |
140 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.52040337 |
141 | regulation of collateral sprouting (GO:0048670) | 2.51620626 |
142 | cardiac chamber formation (GO:0003207) | 2.48255938 |
143 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.47890613 |
144 | regulation of development, heterochronic (GO:0040034) | 2.47284597 |
145 | cell proliferation in forebrain (GO:0021846) | 2.47085472 |
146 | regulation of membrane repolarization (GO:0060306) | 2.47058588 |
147 | synapse organization (GO:0050808) | 2.46801846 |
148 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.45364734 |
149 | cyclic nucleotide catabolic process (GO:0009214) | 2.45021043 |
150 | regulation of action potential (GO:0098900) | 2.43779699 |
151 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.43128293 |
152 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.42714927 |
153 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.41991061 |
154 | regulation of neurotransmitter uptake (GO:0051580) | 2.41795455 |
155 | neuronal action potential (GO:0019228) | 2.40242584 |
156 | righting reflex (GO:0060013) | 2.39442945 |
157 | regulation of dendritic spine development (GO:0060998) | 2.39230292 |
158 | neuromuscular synaptic transmission (GO:0007274) | 2.38587603 |
159 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.38356790 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.11272774 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.11375437 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.22370771 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.09881250 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.98426200 |
6 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.77784428 |
7 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.77122011 |
8 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.73653358 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.64114876 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.64114876 |
11 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.60844899 |
12 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.60649152 |
13 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.59115017 |
14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.50561606 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.45221192 |
16 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.38835160 |
17 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.35251415 |
18 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.34690376 |
19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.31560358 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.28146882 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.26809162 |
22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.20614236 |
23 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.18851734 |
24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.18844345 |
25 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.16137612 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.09412082 |
27 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.04413623 |
28 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.00050136 |
29 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.99414740 |
30 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.99255535 |
31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.92025904 |
32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91641923 |
33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.90293493 |
34 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.80186475 |
35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.78143904 |
36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73744012 |
37 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.70678369 |
38 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.68862344 |
39 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.68564370 |
40 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.67864136 |
41 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.65964007 |
42 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.64507178 |
43 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.56833457 |
44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.54896917 |
45 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.51853068 |
46 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.50128135 |
47 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.48844285 |
48 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.46357685 |
49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.43428915 |
50 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.40912667 |
51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40905419 |
52 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39235127 |
53 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.38418092 |
54 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.37364189 |
55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.37364189 |
56 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.37304432 |
57 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.37285635 |
58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.37059888 |
59 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.36422416 |
60 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.35147835 |
61 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.34633336 |
62 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.33637878 |
63 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.32515621 |
64 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.31878337 |
65 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29446494 |
66 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.28867909 |
67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23226437 |
68 | AR_19668381_ChIP-Seq_PC3_Human | 1.21350228 |
69 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20961547 |
70 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.20535991 |
71 | STAT3_23295773_ChIP-Seq_U87_Human | 1.20518725 |
72 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.19784831 |
73 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.19391214 |
74 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19164806 |
75 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.18995779 |
76 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.17260494 |
77 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.16562464 |
78 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.16483691 |
79 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.15864577 |
80 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.15767394 |
81 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.14592957 |
82 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.13634805 |
83 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.13543720 |
84 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13427726 |
85 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.12987599 |
86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12030963 |
87 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11481093 |
88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.10864351 |
89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.10386202 |
90 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.09719498 |
91 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07824962 |
92 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07682109 |
93 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.06903825 |
94 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05648021 |
95 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.05639001 |
96 | JUN_21703547_ChIP-Seq_K562_Human | 1.05501856 |
97 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.05180878 |
98 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.04733816 |
99 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.04643155 |
100 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01561670 |
101 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.01559999 |
102 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01523140 |
103 | * KDM2B_26808549_Chip-Seq_REH_Human | 1.00781346 |
104 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.00564392 |
105 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00186617 |
106 | VDR_22108803_ChIP-Seq_LS180_Human | 0.99861431 |
107 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.99156421 |
108 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.97269925 |
109 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.96498375 |
110 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.96071751 |
111 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.95920374 |
112 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.95545672 |
113 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.95494577 |
114 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.94984112 |
115 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94573754 |
116 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94573754 |
117 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.92814944 |
118 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.92152751 |
119 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.92148528 |
120 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.91846698 |
121 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.89829247 |
122 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.89162769 |
123 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.89128494 |
124 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.88988575 |
125 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 0.88142318 |
126 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.87910764 |
127 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87241874 |
128 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.83202418 |
129 | EWS_26573619_Chip-Seq_HEK293_Human | 0.82018245 |
130 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.81121344 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.37526974 |
2 | MP0003880_abnormal_central_pattern | 4.34075531 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.72839168 |
4 | MP0004270_analgesia | 3.21798155 |
5 | MP0002063_abnormal_learning/memory/cond | 3.13334222 |
6 | MP0009745_abnormal_behavioral_response | 2.94154087 |
7 | MP0001968_abnormal_touch/_nociception | 2.71096900 |
8 | MP0002572_abnormal_emotion/affect_behav | 2.71074402 |
9 | MP0002064_seizures | 2.62093781 |
10 | MP0003787_abnormal_imprinting | 2.52558540 |
11 | MP0009046_muscle_twitch | 2.52301563 |
12 | MP0002734_abnormal_mechanical_nocicepti | 2.32412842 |
13 | MP0005646_abnormal_pituitary_gland | 2.22725280 |
14 | MP0005423_abnormal_somatic_nervous | 2.19714331 |
15 | MP0001486_abnormal_startle_reflex | 2.18802162 |
16 | MP0002735_abnormal_chemical_nociception | 2.18167670 |
17 | MP0002736_abnormal_nociception_after | 2.17100210 |
18 | MP0003122_maternal_imprinting | 2.16141913 |
19 | MP0002272_abnormal_nervous_system | 2.15955714 |
20 | MP0002102_abnormal_ear_morphology | 2.15072268 |
21 | MP0006276_abnormal_autonomic_nervous | 2.13907033 |
22 | MP0002822_catalepsy | 2.04006987 |
23 | MP0000778_abnormal_nervous_system | 2.02253695 |
24 | MP0002733_abnormal_thermal_nociception | 2.00151934 |
25 | MP0002184_abnormal_innervation | 1.96338452 |
26 | MP0001440_abnormal_grooming_behavior | 1.92895489 |
27 | MP0002557_abnormal_social/conspecific_i | 1.87385013 |
28 | MP0001188_hyperpigmentation | 1.85102543 |
29 | MP0009780_abnormal_chondrocyte_physiolo | 1.82231771 |
30 | MP0001970_abnormal_pain_threshold | 1.80666675 |
31 | MP0002909_abnormal_adrenal_gland | 1.80010584 |
32 | MP0002067_abnormal_sensory_capabilities | 1.77279105 |
33 | MP0001984_abnormal_olfaction | 1.77048132 |
34 | MP0001529_abnormal_vocalization | 1.74773534 |
35 | MP0005253_abnormal_eye_physiology | 1.67825631 |
36 | MP0001501_abnormal_sleep_pattern | 1.66726642 |
37 | MP0004811_abnormal_neuron_physiology | 1.65627268 |
38 | MP0004924_abnormal_behavior | 1.60100339 |
39 | MP0005386_behavior/neurological_phenoty | 1.60100339 |
40 | MP0006292_abnormal_olfactory_placode | 1.58731621 |
41 | MP0004858_abnormal_nervous_system | 1.57973042 |
42 | MP0000955_abnormal_spinal_cord | 1.52347339 |
43 | MP0005645_abnormal_hypothalamus_physiol | 1.48112890 |
44 | MP0003011_delayed_dark_adaptation | 1.47098650 |
45 | MP0001986_abnormal_taste_sensitivity | 1.44157156 |
46 | MP0003195_calcinosis | 1.43994280 |
47 | MP0003283_abnormal_digestive_organ | 1.43609528 |
48 | MP0008569_lethality_at_weaning | 1.42513485 |
49 | MP0003121_genomic_imprinting | 1.41678637 |
50 | MP0003879_abnormal_hair_cell | 1.40182814 |
51 | MP0001502_abnormal_circadian_rhythm | 1.38366020 |
52 | MP0005187_abnormal_penis_morphology | 1.35871788 |
53 | MP0002882_abnormal_neuron_morphology | 1.35870674 |
54 | MP0001905_abnormal_dopamine_level | 1.34378000 |
55 | MP0000569_abnormal_digit_pigmentation | 1.31276785 |
56 | MP0005367_renal/urinary_system_phenotyp | 1.30276873 |
57 | MP0000516_abnormal_urinary_system | 1.30276873 |
58 | MP0002837_dystrophic_cardiac_calcinosis | 1.28212991 |
59 | MP0002066_abnormal_motor_capabilities/c | 1.26136898 |
60 | MP0002638_abnormal_pupillary_reflex | 1.25035267 |
61 | MP0010386_abnormal_urinary_bladder | 1.20731507 |
62 | MP0000631_abnormal_neuroendocrine_gland | 1.20114085 |
63 | MP0003123_paternal_imprinting | 1.17157973 |
64 | MP0002152_abnormal_brain_morphology | 1.15668141 |
65 | MP0001485_abnormal_pinna_reflex | 1.12820858 |
66 | MP0002653_abnormal_ependyma_morphology | 1.12812188 |
67 | MP0005394_taste/olfaction_phenotype | 1.12756698 |
68 | MP0005499_abnormal_olfactory_system | 1.12756698 |
69 | MP0000013_abnormal_adipose_tissue | 1.11309248 |
70 | MP0004142_abnormal_muscle_tone | 1.10520993 |
71 | MP0003755_abnormal_palate_morphology | 1.05499452 |
72 | MP0000751_myopathy | 1.01432454 |
73 | MP0008872_abnormal_physiological_respon | 1.01336889 |
74 | MP0004134_abnormal_chest_morphology | 1.00744957 |
75 | MP0002751_abnormal_autonomic_nervous | 0.98913365 |
76 | MP0004885_abnormal_endolymph | 0.97595914 |
77 | MP0006072_abnormal_retinal_apoptosis | 0.94596494 |
78 | MP0005379_endocrine/exocrine_gland_phen | 0.93239053 |
79 | MP0004085_abnormal_heartbeat | 0.90357779 |
80 | MP0001270_distended_abdomen | 0.90067167 |
81 | MP0002233_abnormal_nose_morphology | 0.88065714 |
82 | MP0003329_amyloid_beta_deposits | 0.87898763 |
83 | MP0004043_abnormal_pH_regulation | 0.87166951 |
84 | MP0002938_white_spotting | 0.87100033 |
85 | MP0003137_abnormal_impulse_conducting | 0.87067353 |
86 | MP0005195_abnormal_posterior_eye | 0.87034380 |
87 | MP0002069_abnormal_eating/drinking_beha | 0.86749108 |
88 | MP0003633_abnormal_nervous_system | 0.84785117 |
89 | MP0008995_early_reproductive_senescence | 0.84713026 |
90 | MP0002752_abnormal_somatic_nervous | 0.84395383 |
91 | MP0003937_abnormal_limbs/digits/tail_de | 0.84091639 |
92 | MP0003861_abnormal_nervous_system | 0.84091235 |
93 | MP0003136_yellow_coat_color | 0.84046381 |
94 | MP0005248_abnormal_Harderian_gland | 0.83066549 |
95 | MP0000678_abnormal_parathyroid_gland | 0.82967679 |
96 | MP0001963_abnormal_hearing_physiology | 0.81681946 |
97 | MP0000049_abnormal_middle_ear | 0.81148095 |
98 | MP0002234_abnormal_pharynx_morphology | 0.77993512 |
99 | MP0008877_abnormal_DNA_methylation | 0.75280423 |
100 | MP0004233_abnormal_muscle_weight | 0.75250141 |
101 | MP0003119_abnormal_digestive_system | 0.73541957 |
102 | MP0004215_abnormal_myocardial_fiber | 0.71430709 |
103 | MP0003631_nervous_system_phenotype | 0.69598321 |
104 | MP0000026_abnormal_inner_ear | 0.69023111 |
105 | MP0003385_abnormal_body_wall | 0.67101513 |
106 | MP0005551_abnormal_eye_electrophysiolog | 0.67098886 |
107 | MP0004133_heterotaxia | 0.66522989 |
108 | MP0004145_abnormal_muscle_electrophysio | 0.65236777 |
109 | MP0008789_abnormal_olfactory_epithelium | 0.64490020 |
110 | MP0005409_darkened_coat_color | 0.62828823 |
111 | MP0002229_neurodegeneration | 0.62796139 |
112 | MP0001664_abnormal_digestion | 0.62678899 |
113 | MP0001299_abnormal_eye_distance/ | 0.60580575 |
114 | MP0001177_atelectasis | 0.60045790 |
115 | MP0001943_abnormal_respiration | 0.58077266 |
116 | MP0004742_abnormal_vestibular_system | 0.57924437 |
117 | MP0003634_abnormal_glial_cell | 0.57744190 |
118 | MP0002082_postnatal_lethality | 0.57632998 |
119 | MP0010770_preweaning_lethality | 0.57632998 |
120 | MP0000534_abnormal_ureter_morphology | 0.57391157 |
121 | MP0003938_abnormal_ear_development | 0.57169419 |
122 | MP0010769_abnormal_survival | 0.56277321 |
123 | MP0002876_abnormal_thyroid_physiology | 0.55560257 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 6.08861912 |
2 | Myokymia (HP:0002411) | 5.30532288 |
3 | Epileptic encephalopathy (HP:0200134) | 4.74548154 |
4 | Focal seizures (HP:0007359) | 4.58644021 |
5 | Visual hallucinations (HP:0002367) | 4.49886879 |
6 | Febrile seizures (HP:0002373) | 4.29442574 |
7 | Progressive cerebellar ataxia (HP:0002073) | 3.93176145 |
8 | Atonic seizures (HP:0010819) | 3.80214381 |
9 | True hermaphroditism (HP:0010459) | 3.72766992 |
10 | Hyperventilation (HP:0002883) | 3.72382199 |
11 | Pancreatic fibrosis (HP:0100732) | 3.59945414 |
12 | Absence seizures (HP:0002121) | 3.52761879 |
13 | Pancreatic cysts (HP:0001737) | 3.52694897 |
14 | Broad-based gait (HP:0002136) | 3.34825636 |
15 | Dialeptic seizures (HP:0011146) | 3.21197027 |
16 | Ankle clonus (HP:0011448) | 3.06813355 |
17 | Abnormality of midbrain morphology (HP:0002418) | 3.01824400 |
18 | Molar tooth sign on MRI (HP:0002419) | 3.01824400 |
19 | Generalized tonic-clonic seizures (HP:0002069) | 2.97235330 |
20 | Pendular nystagmus (HP:0012043) | 2.96442044 |
21 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.93240246 |
22 | Nephronophthisis (HP:0000090) | 2.91553624 |
23 | Amblyopia (HP:0000646) | 2.89658073 |
24 | Type II lissencephaly (HP:0007260) | 2.85201052 |
25 | Pachygyria (HP:0001302) | 2.84104290 |
26 | Excessive salivation (HP:0003781) | 2.78267684 |
27 | Drooling (HP:0002307) | 2.78267684 |
28 | Epileptiform EEG discharges (HP:0011182) | 2.77902149 |
29 | Limb dystonia (HP:0002451) | 2.75327777 |
30 | Poor eye contact (HP:0000817) | 2.70807031 |
31 | EEG with generalized epileptiform discharges (HP:0011198) | 2.67160096 |
32 | Truncal ataxia (HP:0002078) | 2.66453522 |
33 | Gait imbalance (HP:0002141) | 2.60797741 |
34 | Depression (HP:0000716) | 2.60498853 |
35 | Anxiety (HP:0000739) | 2.53960570 |
36 | Hypsarrhythmia (HP:0002521) | 2.51443245 |
37 | Gaze-evoked nystagmus (HP:0000640) | 2.50535535 |
38 | Intestinal atresia (HP:0011100) | 2.50433421 |
39 | Chronic hepatic failure (HP:0100626) | 2.47886618 |
40 | Progressive macrocephaly (HP:0004481) | 2.46282579 |
41 | Supranuclear gaze palsy (HP:0000605) | 2.45033350 |
42 | Protruding tongue (HP:0010808) | 2.40410991 |
43 | Absent speech (HP:0001344) | 2.40008108 |
44 | Acute necrotizing encephalopathy (HP:0006965) | 2.36897669 |
45 | Abnormality of the renal medulla (HP:0100957) | 2.35999759 |
46 | Mutism (HP:0002300) | 2.35950301 |
47 | Keratoconus (HP:0000563) | 2.35911575 |
48 | Increased corneal curvature (HP:0100692) | 2.35911575 |
49 | Agitation (HP:0000713) | 2.35098380 |
50 | Action tremor (HP:0002345) | 2.34705822 |
51 | Polyphagia (HP:0002591) | 2.33246738 |
52 | Hemiparesis (HP:0001269) | 2.32538787 |
53 | Genetic anticipation (HP:0003743) | 2.30951790 |
54 | Renal cortical cysts (HP:0000803) | 2.29138374 |
55 | Progressive inability to walk (HP:0002505) | 2.29021136 |
56 | Optic nerve hypoplasia (HP:0000609) | 2.28358599 |
57 | Abnormal eating behavior (HP:0100738) | 2.26750046 |
58 | Impaired social interactions (HP:0000735) | 2.24577169 |
59 | Abnormal social behavior (HP:0012433) | 2.24577169 |
60 | Hypothermia (HP:0002045) | 2.22851629 |
61 | Abnormality of the renal cortex (HP:0011035) | 2.22468429 |
62 | Megalencephaly (HP:0001355) | 2.21430365 |
63 | Pheochromocytoma (HP:0002666) | 2.20689316 |
64 | Abnormality of the lower motor neuron (HP:0002366) | 2.20515121 |
65 | Abolished electroretinogram (ERG) (HP:0000550) | 2.20079961 |
66 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.17530814 |
67 | Torticollis (HP:0000473) | 2.16169644 |
68 | Dysdiadochokinesis (HP:0002075) | 2.15213926 |
69 | Congenital primary aphakia (HP:0007707) | 2.15193671 |
70 | Cystic liver disease (HP:0006706) | 2.15143144 |
71 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.14915421 |
72 | Sclerocornea (HP:0000647) | 2.14752297 |
73 | Postaxial hand polydactyly (HP:0001162) | 2.12659490 |
74 | Stereotypic behavior (HP:0000733) | 2.09731021 |
75 | Obstructive sleep apnea (HP:0002870) | 2.09458556 |
76 | Hypoplasia of the brainstem (HP:0002365) | 2.08717933 |
77 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.08717933 |
78 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.07236566 |
79 | Medial flaring of the eyebrow (HP:0010747) | 2.06381041 |
80 | Nephrogenic diabetes insipidus (HP:0009806) | 2.05206044 |
81 | Abnormal hair whorl (HP:0010721) | 2.04652974 |
82 | Impaired smooth pursuit (HP:0007772) | 2.04649391 |
83 | Focal dystonia (HP:0004373) | 2.04207167 |
84 | Oligodactyly (hands) (HP:0001180) | 2.04118632 |
85 | Occipital encephalocele (HP:0002085) | 2.03989830 |
86 | Poor coordination (HP:0002370) | 2.03267656 |
87 | Decreased central vision (HP:0007663) | 2.02269356 |
88 | Lissencephaly (HP:0001339) | 2.01261526 |
89 | Split foot (HP:0001839) | 2.00310861 |
90 | Anencephaly (HP:0002323) | 1.99758267 |
91 | Inability to walk (HP:0002540) | 1.99337298 |
92 | Fetal akinesia sequence (HP:0001989) | 1.98822058 |
93 | Hepatoblastoma (HP:0002884) | 1.98659149 |
94 | Specific learning disability (HP:0001328) | 1.97615382 |
95 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.97280869 |
96 | Neuroendocrine neoplasm (HP:0100634) | 1.96748509 |
97 | Urinary urgency (HP:0000012) | 1.96519007 |
98 | Papilledema (HP:0001085) | 1.93019514 |
99 | Methylmalonic acidemia (HP:0002912) | 1.92760900 |
100 | Postaxial foot polydactyly (HP:0001830) | 1.92679147 |
101 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.92481033 |
102 | Attenuation of retinal blood vessels (HP:0007843) | 1.92193817 |
103 | Sleep apnea (HP:0010535) | 1.90730312 |
104 | Acute encephalopathy (HP:0006846) | 1.90464183 |
105 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.90070423 |
106 | Short tibia (HP:0005736) | 1.89515048 |
107 | Colon cancer (HP:0003003) | 1.88520664 |
108 | Hypoplastic pelvis (HP:0008839) | 1.88462406 |
109 | Congenital stationary night blindness (HP:0007642) | 1.88437381 |
110 | Chorioretinal atrophy (HP:0000533) | 1.87756169 |
111 | Retinal dysplasia (HP:0007973) | 1.87629662 |
112 | Spastic tetraplegia (HP:0002510) | 1.87055866 |
113 | Hypoventilation (HP:0002791) | 1.85784213 |
114 | Dysmetria (HP:0001310) | 1.84384176 |
115 | Abnormal EKG (HP:0003115) | 1.83933302 |
116 | Poor suck (HP:0002033) | 1.83763044 |
117 | Narrow forehead (HP:0000341) | 1.83141692 |
118 | Abnormality of the astrocytes (HP:0100707) | 1.82411113 |
119 | Astrocytoma (HP:0009592) | 1.82411113 |
120 | Mitochondrial inheritance (HP:0001427) | 1.81793294 |
121 | Esotropia (HP:0000565) | 1.81044275 |
122 | Abnormality of binocular vision (HP:0011514) | 1.79760672 |
123 | Diplopia (HP:0000651) | 1.79760672 |
124 | Amyotrophic lateral sclerosis (HP:0007354) | 1.79641757 |
125 | Male pseudohermaphroditism (HP:0000037) | 1.79188013 |
126 | Incomplete penetrance (HP:0003829) | 1.77805900 |
127 | Narrow nasal bridge (HP:0000446) | 1.77158773 |
128 | Bradykinesia (HP:0002067) | 1.77034945 |
129 | Dyskinesia (HP:0100660) | 1.76831548 |
130 | Abnormality of salivation (HP:0100755) | 1.76729138 |
131 | Spinal canal stenosis (HP:0003416) | 1.76700384 |
132 | Abnormality of the labia minora (HP:0012880) | 1.76485662 |
133 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.76272825 |
134 | Renal hypoplasia (HP:0000089) | 1.75453933 |
135 | Furrowed tongue (HP:0000221) | 1.75044507 |
136 | Spastic gait (HP:0002064) | 1.74959441 |
137 | Failure to thrive in infancy (HP:0001531) | 1.74556602 |
138 | Craniofacial dystonia (HP:0012179) | 1.73546163 |
139 | Congenital hepatic fibrosis (HP:0002612) | 1.72235409 |
140 | Postural instability (HP:0002172) | 1.68583053 |
141 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.67989521 |
142 | Abnormality of vitamin B metabolism (HP:0004340) | 1.67982387 |
143 | Scanning speech (HP:0002168) | 1.66460764 |
144 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.66192945 |
145 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.66105390 |
146 | Prolonged QT interval (HP:0001657) | 1.65989431 |
147 | Abnormality of the corticospinal tract (HP:0002492) | 1.65616443 |
148 | Congenital sensorineural hearing impairment (HP:0008527) | 1.65028755 |
149 | Increased CSF lactate (HP:0002490) | 1.64865750 |
150 | Decreased circulating renin level (HP:0003351) | 1.64658961 |
151 | Impaired vibratory sensation (HP:0002495) | 1.64082683 |
152 | Cerebellar dysplasia (HP:0007033) | 1.64008232 |
153 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.63802377 |
154 | Gait ataxia (HP:0002066) | 1.62179643 |
155 | Lower limb muscle weakness (HP:0007340) | 1.62051477 |
156 | Genital tract atresia (HP:0001827) | 1.62030813 |
157 | Gastroesophageal reflux (HP:0002020) | 1.61819462 |
158 | Vaginal atresia (HP:0000148) | 1.60649291 |
159 | Shoulder girdle muscle weakness (HP:0003547) | 1.60473634 |
160 | Exotropia (HP:0000577) | 1.60296175 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.86802087 |
2 | EPHA4 | 4.63666848 |
3 | MARK1 | 4.24757521 |
4 | FRK | 3.71598735 |
5 | MAP3K4 | 3.07480001 |
6 | CASK | 3.02323557 |
7 | MAP2K7 | 2.87317361 |
8 | MAP3K9 | 2.74304151 |
9 | MINK1 | 2.73993830 |
10 | MAP4K2 | 2.53852527 |
11 | NTRK2 | 2.30543768 |
12 | TNIK | 2.25996458 |
13 | MAPK13 | 2.18233482 |
14 | EPHA3 | 2.05067058 |
15 | KSR1 | 1.78755546 |
16 | DAPK2 | 1.75591637 |
17 | MAP3K12 | 1.68094427 |
18 | PAK6 | 1.65306609 |
19 | CSNK1G3 | 1.63465154 |
20 | TRIM28 | 1.61990549 |
21 | DAPK1 | 1.58483779 |
22 | CAMKK2 | 1.58021558 |
23 | PLK2 | 1.57573678 |
24 | PRPF4B | 1.55594319 |
25 | BMPR1B | 1.55047060 |
26 | SIK3 | 1.50560282 |
27 | GRK1 | 1.50368069 |
28 | CSNK1G1 | 1.49475969 |
29 | PRKD3 | 1.44635809 |
30 | CDK5 | 1.43341831 |
31 | CSNK1A1L | 1.43294667 |
32 | MAP2K4 | 1.41448998 |
33 | CAMKK1 | 1.39706922 |
34 | SIK2 | 1.37372887 |
35 | PRKCG | 1.28497376 |
36 | UHMK1 | 1.21386881 |
37 | GRK5 | 1.20151810 |
38 | NTRK1 | 1.17820132 |
39 | ARAF | 1.17525054 |
40 | DYRK2 | 1.16655744 |
41 | INSRR | 1.15143333 |
42 | NUAK1 | 1.15130003 |
43 | KSR2 | 1.13890828 |
44 | PHKG2 | 1.09648383 |
45 | PHKG1 | 1.09648383 |
46 | LATS2 | 1.05176051 |
47 | FGFR2 | 1.04523546 |
48 | FES | 1.02776398 |
49 | RIPK4 | 1.01359349 |
50 | STK38L | 1.00332057 |
51 | DYRK1A | 1.00272909 |
52 | OXSR1 | 0.98334646 |
53 | AKT3 | 0.98276157 |
54 | CDK18 | 0.96105525 |
55 | SGK2 | 0.95262696 |
56 | CDK14 | 0.93954374 |
57 | SGK223 | 0.93609374 |
58 | SGK494 | 0.93609374 |
59 | CAMK2A | 0.90968226 |
60 | DYRK3 | 0.87703007 |
61 | MKNK2 | 0.87524960 |
62 | CDK15 | 0.87498277 |
63 | CAMK1 | 0.86280924 |
64 | BCKDK | 0.86124002 |
65 | ERBB3 | 0.85166453 |
66 | CDK19 | 0.83910781 |
67 | STK39 | 0.81499187 |
68 | PKN1 | 0.81309956 |
69 | CAMK2B | 0.80426338 |
70 | MARK2 | 0.78830393 |
71 | NME1 | 0.78550916 |
72 | CDK11A | 0.78131378 |
73 | MAP3K2 | 0.75292890 |
74 | ZAK | 0.74938465 |
75 | BRAF | 0.74720419 |
76 | OBSCN | 0.72723999 |
77 | PTK2B | 0.71586498 |
78 | PAK3 | 0.71569577 |
79 | PRKCE | 0.70219732 |
80 | FER | 0.69411852 |
81 | TYRO3 | 0.67302704 |
82 | CSNK1G2 | 0.66129601 |
83 | PNCK | 0.65044621 |
84 | ADRBK2 | 0.63953436 |
85 | BCR | 0.63804426 |
86 | RPS6KA2 | 0.60450141 |
87 | CAMK4 | 0.60355016 |
88 | CCNB1 | 0.59666076 |
89 | STK38 | 0.57337613 |
90 | PINK1 | 0.56259943 |
91 | RAF1 | 0.54934587 |
92 | BMPR2 | 0.54340467 |
93 | SGK1 | 0.52429595 |
94 | CSNK1A1 | 0.52129821 |
95 | WNK3 | 0.52114297 |
96 | PRKCZ | 0.51508034 |
97 | SRPK1 | 0.51222389 |
98 | SGK3 | 0.51199457 |
99 | MUSK | 0.50205036 |
100 | WNK4 | 0.48954687 |
101 | MAP3K6 | 0.48408300 |
102 | LIMK1 | 0.47502894 |
103 | CAMK2D | 0.46179240 |
104 | CSNK1D | 0.45683177 |
105 | VRK1 | 0.45328198 |
106 | PRKCH | 0.44906171 |
107 | EPHB2 | 0.44241051 |
108 | MAPKAPK5 | 0.43948006 |
109 | LMTK2 | 0.43739431 |
110 | PRKD2 | 0.42629590 |
111 | PASK | 0.42485025 |
112 | PRKG1 | 0.42406844 |
113 | ADRBK1 | 0.41645708 |
114 | MAP2K1 | 0.41170091 |
115 | CDC42BPA | 0.41161867 |
116 | ROCK1 | 0.39886932 |
117 | PRKAA1 | 0.39419166 |
118 | DDR2 | 0.39394105 |
119 | RET | 0.39391950 |
120 | PLK4 | 0.39160321 |
121 | PRKCI | 0.39118898 |
122 | RPS6KA3 | 0.38503906 |
123 | HIPK2 | 0.38231798 |
124 | MAPK10 | 0.37622248 |
125 | RPS6KA4 | 0.37436000 |
126 | STK11 | 0.37373482 |
127 | EIF2AK3 | 0.36732144 |
128 | BRSK1 | 0.36501163 |
129 | CDK3 | 0.36172042 |
130 | TAOK1 | 0.36100171 |
131 | CAMK2G | 0.35634287 |
132 | PRKACB | 0.35553916 |
133 | PRKACA | 0.35009205 |
134 | YES1 | 0.34675450 |
135 | FGR | 0.34203589 |
136 | PLK3 | 0.33859571 |
137 | GRK7 | 0.32133075 |
138 | MKNK1 | 0.31016351 |
139 | CSNK1E | 0.28347934 |
140 | RPS6KA5 | 0.26343442 |
141 | NEK1 | 0.24831028 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.75519702 |
2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.17004808 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.13529805 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.82401971 |
5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.75446622 |
6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.71848400 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.71332378 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 2.60810673 |
9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.59569607 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.59386208 |
11 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.49931134 |
12 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.47107696 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.31263654 |
14 | Insulin secretion_Homo sapiens_hsa04911 | 2.20099244 |
15 | Taste transduction_Homo sapiens_hsa04742 | 2.15793093 |
16 | Cocaine addiction_Homo sapiens_hsa05030 | 2.06668279 |
17 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.02295125 |
18 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.92293227 |
19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.91970993 |
20 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.90920293 |
21 | Protein export_Homo sapiens_hsa03060 | 1.87834476 |
22 | Salivary secretion_Homo sapiens_hsa04970 | 1.82361733 |
23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.74153342 |
24 | Long-term depression_Homo sapiens_hsa04730 | 1.67744901 |
25 | Renin secretion_Homo sapiens_hsa04924 | 1.65313533 |
26 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.63573436 |
27 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.62709867 |
28 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.58934737 |
29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.58264752 |
30 | Gap junction_Homo sapiens_hsa04540 | 1.57810016 |
31 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.55610056 |
32 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.54694869 |
33 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.49153237 |
34 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.47369868 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.46063344 |
36 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.42751132 |
37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.36243500 |
38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.33326813 |
39 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.32319995 |
40 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32149385 |
41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.29202604 |
42 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.28522785 |
43 | Axon guidance_Homo sapiens_hsa04360 | 1.28073655 |
44 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.25715618 |
45 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.21626283 |
46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.21607372 |
47 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.21272725 |
48 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.17859607 |
49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.11278452 |
50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.10308799 |
51 | Melanogenesis_Homo sapiens_hsa04916 | 1.09371602 |
52 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.07364487 |
53 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.07015115 |
54 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06862889 |
55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.06635396 |
56 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.05140794 |
57 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.02979710 |
58 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.02688143 |
59 | Glioma_Homo sapiens_hsa05214 | 1.02120147 |
60 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.99705740 |
61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97240668 |
62 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.94718453 |
63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.92822384 |
64 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.90154977 |
65 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.89012378 |
66 | Peroxisome_Homo sapiens_hsa04146 | 0.88053690 |
67 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.87675330 |
68 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.87652273 |
69 | Basal transcription factors_Homo sapiens_hsa03022 | 0.85580637 |
70 | Alcoholism_Homo sapiens_hsa05034 | 0.85154507 |
71 | Alzheimers disease_Homo sapiens_hsa05010 | 0.83404756 |
72 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.82942735 |
73 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.81573293 |
74 | Circadian rhythm_Homo sapiens_hsa04710 | 0.81555779 |
75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.80619817 |
76 | Phototransduction_Homo sapiens_hsa04744 | 0.79840285 |
77 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.76332951 |
78 | Parkinsons disease_Homo sapiens_hsa05012 | 0.73810450 |
79 | RNA polymerase_Homo sapiens_hsa03020 | 0.73763430 |
80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72613583 |
81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.72166549 |
82 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71787517 |
83 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.71376456 |
84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.69984327 |
85 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.69825508 |
86 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.69678592 |
87 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.67829924 |
88 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.64933630 |
89 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.64179514 |
90 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.63877659 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63437168 |
92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62091669 |
93 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.62087973 |
94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.62012784 |
95 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.61586584 |
96 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61269993 |
97 | Huntingtons disease_Homo sapiens_hsa05016 | 0.59885546 |
98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.59161887 |
99 | Endometrial cancer_Homo sapiens_hsa05213 | 0.58763852 |
100 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.57957977 |
101 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.57927257 |
102 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.57503521 |
103 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.56851413 |
104 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.55538629 |
105 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55109278 |
106 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.54608561 |
107 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.54070836 |
108 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53718576 |
109 | Colorectal cancer_Homo sapiens_hsa05210 | 0.53715922 |
110 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.53653305 |
111 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50957036 |
112 | RNA degradation_Homo sapiens_hsa03018 | 0.50466116 |
113 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.49753120 |
114 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.49472661 |
115 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47807689 |
116 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47216377 |
117 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.47076968 |
118 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.46402393 |
119 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.44352307 |
120 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.44331709 |
121 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.44250211 |
122 | ABC transporters_Homo sapiens_hsa02010 | 0.41801759 |
123 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41781923 |
124 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41688673 |
125 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.41261683 |
126 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.41014439 |
127 | Metabolic pathways_Homo sapiens_hsa01100 | 0.40978697 |
128 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.40504975 |
129 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38737266 |
130 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38311641 |
131 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38025431 |
132 | Melanoma_Homo sapiens_hsa05218 | 0.37855191 |
133 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.36470157 |
134 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36324384 |
135 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35996610 |
136 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.35599891 |
137 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35514664 |
138 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.35435071 |
139 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34009776 |
140 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.33644621 |
141 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.33034170 |
142 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.32139757 |
143 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.31491389 |
144 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.31253537 |
145 | Prion diseases_Homo sapiens_hsa05020 | 0.30976126 |
146 | Endocytosis_Homo sapiens_hsa04144 | 0.30535399 |
147 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.29862402 |