FAM110B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.48567936
2vocalization behavior (GO:0071625)5.26129649
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.05872741
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.98189899
5synaptic vesicle exocytosis (GO:0016079)4.89973183
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.82160523
7neuron cell-cell adhesion (GO:0007158)4.82147387
8regulation of glutamate receptor signaling pathway (GO:1900449)4.76992638
9protein localization to synapse (GO:0035418)4.64631979
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.60487970
11nucleobase catabolic process (GO:0046113)4.59421311
12regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.54976367
13synaptic vesicle maturation (GO:0016188)4.44606465
14regulation of synaptic vesicle exocytosis (GO:2000300)4.41064243
15glutamate secretion (GO:0014047)4.37231031
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.36022077
17regulation of synapse structural plasticity (GO:0051823)4.26313832
18postsynaptic membrane organization (GO:0001941)4.26095859
19locomotory exploration behavior (GO:0035641)4.18586525
20glutamate receptor signaling pathway (GO:0007215)4.11066777
21limb bud formation (GO:0060174)4.08721116
22synaptic transmission, glutamatergic (GO:0035249)4.01967606
23positive regulation of synapse maturation (GO:0090129)4.00730934
24regulation of synaptic vesicle transport (GO:1902803)3.97480180
25exploration behavior (GO:0035640)3.90925488
26neurotransmitter-gated ion channel clustering (GO:0072578)3.90103660
27neuron-neuron synaptic transmission (GO:0007270)3.88868154
28regulation of long-term neuronal synaptic plasticity (GO:0048169)3.84775579
29neuron recognition (GO:0008038)3.84071811
30presynaptic membrane assembly (GO:0097105)3.81945968
31regulation of neuronal synaptic plasticity (GO:0048168)3.80833063
32synaptic vesicle endocytosis (GO:0048488)3.77757181
33neurotransmitter secretion (GO:0007269)3.76194363
34neuronal action potential propagation (GO:0019227)3.73158497
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.68548310
36positive regulation of synaptic transmission, GABAergic (GO:0032230)3.63812125
37synaptic vesicle docking involved in exocytosis (GO:0016081)3.62827366
38layer formation in cerebral cortex (GO:0021819)3.58743799
39cell migration in hindbrain (GO:0021535)3.57639055
40presynaptic membrane organization (GO:0097090)3.55507294
41dendritic spine morphogenesis (GO:0060997)3.53844436
42response to pheromone (GO:0019236)3.53414472
43axonal fasciculation (GO:0007413)3.52664263
44membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.52269833
45regulation of excitatory postsynaptic membrane potential (GO:0060079)3.50711956
46behavioral fear response (GO:0001662)3.44784696
47behavioral defense response (GO:0002209)3.44784696
48positive regulation of membrane potential (GO:0045838)3.42935868
49long-term memory (GO:0007616)3.39457000
50adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.37410543
51G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.33156856
52regulation of postsynaptic membrane potential (GO:0060078)3.31940635
53regulation of synaptic transmission, glutamatergic (GO:0051966)3.31494598
54glial cell proliferation (GO:0014009)3.25113707
55regulation of dendritic spine morphogenesis (GO:0061001)3.24462218
56regulation of synapse maturation (GO:0090128)3.23282134
57glycosphingolipid biosynthetic process (GO:0006688)3.23152960
58dendrite morphogenesis (GO:0048813)3.23144989
59C4-dicarboxylate transport (GO:0015740)3.22170538
60positive regulation of mitochondrial fission (GO:0090141)3.22097751
61central nervous system projection neuron axonogenesis (GO:0021952)3.22034340
62positive regulation of synapse assembly (GO:0051965)3.20870741
63positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.18900860
64positive regulation of dendritic spine morphogenesis (GO:0061003)3.18759603
65fear response (GO:0042596)3.18211315
66dopamine receptor signaling pathway (GO:0007212)3.17070018
67gamma-aminobutyric acid signaling pathway (GO:0007214)3.16229015
68prepulse inhibition (GO:0060134)3.15540672
69activation of protein kinase A activity (GO:0034199)3.15353395
70negative regulation of synaptic transmission, GABAergic (GO:0032229)3.14569754
71negative regulation of oligodendrocyte differentiation (GO:0048715)3.13335149
72response to histamine (GO:0034776)3.12804484
73regulation of synaptic plasticity (GO:0048167)3.10856103
74synapse assembly (GO:0007416)3.10849960
75innervation (GO:0060384)3.09611102
76protein-cofactor linkage (GO:0018065)3.08466268
77long-term synaptic potentiation (GO:0060291)3.07870330
78sympathetic nervous system development (GO:0048485)3.06890608
79proline transport (GO:0015824)3.05389516
80regulation of neurotransmitter secretion (GO:0046928)3.04661507
81regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.03431630
82negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.02991958
83striatum development (GO:0021756)3.02962230
84transmission of nerve impulse (GO:0019226)3.01532082
85neural tube formation (GO:0001841)3.00455404
86mechanosensory behavior (GO:0007638)2.98680056
87auditory behavior (GO:0031223)2.98007591
88gamma-aminobutyric acid transport (GO:0015812)2.96462484
89response to auditory stimulus (GO:0010996)2.96372271
90learning (GO:0007612)2.96357108
91cell communication by electrical coupling (GO:0010644)2.95813110
92neurotransmitter transport (GO:0006836)2.95764321
93behavioral response to nicotine (GO:0035095)2.95500282
94negative regulation of dendrite development (GO:2000171)2.95281197
95membrane depolarization during action potential (GO:0086010)2.94903590
96G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.92677790
97positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.92634880
98regulation of vesicle fusion (GO:0031338)2.91260073
99regulation of neurotransmitter transport (GO:0051588)2.90546951
100detection of calcium ion (GO:0005513)2.89179796
101membrane depolarization (GO:0051899)2.88794251
102inositol phosphate catabolic process (GO:0071545)2.88528667
103cornea development in camera-type eye (GO:0061303)2.85708691
104dendritic spine organization (GO:0097061)2.85184395
105startle response (GO:0001964)2.82613130
106regulation of synaptic transmission, GABAergic (GO:0032228)2.81993815
107synaptic transmission (GO:0007268)2.81561836
108regulation of cAMP-dependent protein kinase activity (GO:2000479)2.81457204
109olfactory bulb development (GO:0021772)2.81352357
110dendrite development (GO:0016358)2.80446820
111positive regulation of dendritic spine development (GO:0060999)2.79647619
112negative regulation of microtubule polymerization (GO:0031115)2.79426310
113regulation of synapse organization (GO:0050807)2.79345558
114synaptic transmission, dopaminergic (GO:0001963)2.79203528
115female mating behavior (GO:0060180)2.79040756
116cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.78071448
117regulation of synapse assembly (GO:0051963)2.77839071
118establishment of synaptic vesicle localization (GO:0097480)2.77475899
119protein polyglutamylation (GO:0018095)2.75957170
120reflex (GO:0060004)2.75352821
121nonmotile primary cilium assembly (GO:0035058)2.72346700
122somite development (GO:0061053)2.72136910
123retinal ganglion cell axon guidance (GO:0031290)2.71495605
124calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.71413600
125cardiac ventricle formation (GO:0003211)2.71386163
126hippocampus development (GO:0021766)2.71005093
127water-soluble vitamin biosynthetic process (GO:0042364)2.70955123
128spinal cord development (GO:0021510)2.69198271
129positive regulation of amino acid transport (GO:0051957)2.68853497
130negative regulation of transcription regulatory region DNA binding (GO:2000678)2.66494576
131establishment of mitochondrion localization (GO:0051654)2.66094521
132cellular ketone body metabolic process (GO:0046950)2.64571926
133protein localization to cilium (GO:0061512)2.63108428
134regulation of cilium movement (GO:0003352)2.60807583
135regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.57433964
136head development (GO:0060322)2.56038367
137negative regulation of axon extension (GO:0030517)2.53335045
138regulation of respiratory system process (GO:0044065)2.52909232
139regulation of timing of cell differentiation (GO:0048505)2.52877366
140positive regulation of potassium ion transmembrane transport (GO:1901381)2.52040337
141regulation of collateral sprouting (GO:0048670)2.51620626
142cardiac chamber formation (GO:0003207)2.48255938
143regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.47890613
144regulation of development, heterochronic (GO:0040034)2.47284597
145cell proliferation in forebrain (GO:0021846)2.47085472
146regulation of membrane repolarization (GO:0060306)2.47058588
147synapse organization (GO:0050808)2.46801846
148regulation of oligodendrocyte differentiation (GO:0048713)2.45364734
149cyclic nucleotide catabolic process (GO:0009214)2.45021043
150regulation of action potential (GO:0098900)2.43779699
151cerebral cortex radially oriented cell migration (GO:0021799)2.43128293
152negative regulation of cytosolic calcium ion concentration (GO:0051481)2.42714927
153positive regulation of oligodendrocyte differentiation (GO:0048714)2.41991061
154regulation of neurotransmitter uptake (GO:0051580)2.41795455
155neuronal action potential (GO:0019228)2.40242584
156righting reflex (GO:0060013)2.39442945
157regulation of dendritic spine development (GO:0060998)2.39230292
158neuromuscular synaptic transmission (GO:0007274)2.38587603
159detection of light stimulus involved in sensory perception (GO:0050962)2.38356790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.11272774
2GBX2_23144817_ChIP-Seq_PC3_Human4.11375437
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.22370771
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.09881250
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98426200
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.77784428
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.77122011
8REST_21632747_ChIP-Seq_MESCs_Mouse2.73653358
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64114876
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64114876
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.60844899
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.60649152
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59115017
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.50561606
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.45221192
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.38835160
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35251415
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.34690376
19CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.31560358
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.28146882
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.26809162
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.20614236
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18851734
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18844345
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.16137612
26CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.09412082
27SALL1_21062744_ChIP-ChIP_HESCs_Human2.04413623
28DROSHA_22980978_ChIP-Seq_HELA_Human2.00050136
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99414740
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.99255535
31IGF1R_20145208_ChIP-Seq_DFB_Human1.92025904
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.91641923
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.90293493
34TAF15_26573619_Chip-Seq_HEK293_Human1.80186475
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.78143904
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.73744012
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.70678369
38* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68862344
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.68564370
40ZNF274_21170338_ChIP-Seq_K562_Hela1.67864136
41SMAD4_21799915_ChIP-Seq_A2780_Human1.65964007
42* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.64507178
43AR_21572438_ChIP-Seq_LNCaP_Human1.56833457
44P300_19829295_ChIP-Seq_ESCs_Human1.54896917
45ER_23166858_ChIP-Seq_MCF-7_Human1.51853068
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50128135
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.48844285
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46357685
49RNF2_27304074_Chip-Seq_NSC_Mouse1.43428915
50BCAT_22108803_ChIP-Seq_LS180_Human1.40912667
51GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40905419
52FUS_26573619_Chip-Seq_HEK293_Human1.39235127
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.38418092
54CBP_20019798_ChIP-Seq_JUKART_Human1.37364189
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37364189
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.37304432
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.37285635
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37059888
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.36422416
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35147835
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.34633336
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.33637878
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32515621
64* AR_25329375_ChIP-Seq_VCAP_Human1.31878337
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29446494
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.28867909
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23226437
68AR_19668381_ChIP-Seq_PC3_Human1.21350228
69TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20961547
70RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.20535991
71STAT3_23295773_ChIP-Seq_U87_Human1.20518725
72* PIAS1_25552417_ChIP-Seq_VCAP_Human1.19784831
73CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19391214
74POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19164806
75YAP1_20516196_ChIP-Seq_MESCs_Mouse1.18995779
76RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.17260494
77RING1B_27294783_Chip-Seq_NPCs_Mouse1.16562464
78PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16483691
79TCF4_22108803_ChIP-Seq_LS180_Human1.15864577
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15767394
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14592957
82FLI1_21867929_ChIP-Seq_TH2_Mouse1.13634805
83MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.13543720
84TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13427726
85KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12987599
86SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12030963
87* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11481093
88EZH2_27294783_Chip-Seq_NPCs_Mouse1.10864351
89EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10386202
90PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09719498
91* RUNX2_22187159_ChIP-Seq_PCA_Human1.07824962
92CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07682109
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.06903825
94FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05648021
95P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05639001
96JUN_21703547_ChIP-Seq_K562_Human1.05501856
97NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.05180878
98BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.04733816
99* TCF4_23295773_ChIP-Seq_U87_Human1.04643155
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01561670
101ZFP281_18757296_ChIP-ChIP_E14_Mouse1.01559999
102LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01523140
103* KDM2B_26808549_Chip-Seq_REH_Human1.00781346
104* P53_22387025_ChIP-Seq_ESCs_Mouse1.00564392
105* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00186617
106VDR_22108803_ChIP-Seq_LS180_Human0.99861431
107NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99156421
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97269925
109* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96498375
110ARNT_22903824_ChIP-Seq_MCF-7_Human0.96071751
111PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.95920374
112* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95545672
113AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95494577
114SMAD3_21741376_ChIP-Seq_ESCs_Human0.94984112
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94573754
116POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94573754
117TP53_20018659_ChIP-ChIP_R1E_Mouse0.92814944
118TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92152751
119PRDM14_20953172_ChIP-Seq_ESCs_Human0.92148528
120WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91846698
121NANOG_18555785_Chip-Seq_ESCs_Mouse0.89829247
122* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89162769
123AHR_22903824_ChIP-Seq_MCF-7_Human0.89128494
124TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.88988575
125* SOX9_26525672_Chip-Seq_HEART_Mouse0.88142318
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.87910764
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87241874
128TP53_18474530_ChIP-ChIP_U2OS_Human0.83202418
129EWS_26573619_Chip-Seq_HEK293_Human0.82018245
130MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.81121344

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.37526974
2MP0003880_abnormal_central_pattern4.34075531
3MP0003635_abnormal_synaptic_transmissio3.72839168
4MP0004270_analgesia3.21798155
5MP0002063_abnormal_learning/memory/cond3.13334222
6MP0009745_abnormal_behavioral_response2.94154087
7MP0001968_abnormal_touch/_nociception2.71096900
8MP0002572_abnormal_emotion/affect_behav2.71074402
9MP0002064_seizures2.62093781
10MP0003787_abnormal_imprinting2.52558540
11MP0009046_muscle_twitch2.52301563
12MP0002734_abnormal_mechanical_nocicepti2.32412842
13MP0005646_abnormal_pituitary_gland2.22725280
14MP0005423_abnormal_somatic_nervous2.19714331
15MP0001486_abnormal_startle_reflex2.18802162
16MP0002735_abnormal_chemical_nociception2.18167670
17MP0002736_abnormal_nociception_after2.17100210
18MP0003122_maternal_imprinting2.16141913
19MP0002272_abnormal_nervous_system2.15955714
20MP0002102_abnormal_ear_morphology2.15072268
21MP0006276_abnormal_autonomic_nervous2.13907033
22MP0002822_catalepsy2.04006987
23MP0000778_abnormal_nervous_system2.02253695
24MP0002733_abnormal_thermal_nociception2.00151934
25MP0002184_abnormal_innervation1.96338452
26MP0001440_abnormal_grooming_behavior1.92895489
27MP0002557_abnormal_social/conspecific_i1.87385013
28MP0001188_hyperpigmentation1.85102543
29MP0009780_abnormal_chondrocyte_physiolo1.82231771
30MP0001970_abnormal_pain_threshold1.80666675
31MP0002909_abnormal_adrenal_gland1.80010584
32MP0002067_abnormal_sensory_capabilities1.77279105
33MP0001984_abnormal_olfaction1.77048132
34MP0001529_abnormal_vocalization1.74773534
35MP0005253_abnormal_eye_physiology1.67825631
36MP0001501_abnormal_sleep_pattern1.66726642
37MP0004811_abnormal_neuron_physiology1.65627268
38MP0004924_abnormal_behavior1.60100339
39MP0005386_behavior/neurological_phenoty1.60100339
40MP0006292_abnormal_olfactory_placode1.58731621
41MP0004858_abnormal_nervous_system1.57973042
42MP0000955_abnormal_spinal_cord1.52347339
43MP0005645_abnormal_hypothalamus_physiol1.48112890
44MP0003011_delayed_dark_adaptation1.47098650
45MP0001986_abnormal_taste_sensitivity1.44157156
46MP0003195_calcinosis1.43994280
47MP0003283_abnormal_digestive_organ1.43609528
48MP0008569_lethality_at_weaning1.42513485
49MP0003121_genomic_imprinting1.41678637
50MP0003879_abnormal_hair_cell1.40182814
51MP0001502_abnormal_circadian_rhythm1.38366020
52MP0005187_abnormal_penis_morphology1.35871788
53MP0002882_abnormal_neuron_morphology1.35870674
54MP0001905_abnormal_dopamine_level1.34378000
55MP0000569_abnormal_digit_pigmentation1.31276785
56MP0005367_renal/urinary_system_phenotyp1.30276873
57MP0000516_abnormal_urinary_system1.30276873
58MP0002837_dystrophic_cardiac_calcinosis1.28212991
59MP0002066_abnormal_motor_capabilities/c1.26136898
60MP0002638_abnormal_pupillary_reflex1.25035267
61MP0010386_abnormal_urinary_bladder1.20731507
62MP0000631_abnormal_neuroendocrine_gland1.20114085
63MP0003123_paternal_imprinting1.17157973
64MP0002152_abnormal_brain_morphology1.15668141
65MP0001485_abnormal_pinna_reflex1.12820858
66MP0002653_abnormal_ependyma_morphology1.12812188
67MP0005394_taste/olfaction_phenotype1.12756698
68MP0005499_abnormal_olfactory_system1.12756698
69MP0000013_abnormal_adipose_tissue1.11309248
70MP0004142_abnormal_muscle_tone1.10520993
71MP0003755_abnormal_palate_morphology1.05499452
72MP0000751_myopathy1.01432454
73MP0008872_abnormal_physiological_respon1.01336889
74MP0004134_abnormal_chest_morphology1.00744957
75MP0002751_abnormal_autonomic_nervous0.98913365
76MP0004885_abnormal_endolymph0.97595914
77MP0006072_abnormal_retinal_apoptosis0.94596494
78MP0005379_endocrine/exocrine_gland_phen0.93239053
79MP0004085_abnormal_heartbeat0.90357779
80MP0001270_distended_abdomen0.90067167
81MP0002233_abnormal_nose_morphology0.88065714
82MP0003329_amyloid_beta_deposits0.87898763
83MP0004043_abnormal_pH_regulation0.87166951
84MP0002938_white_spotting0.87100033
85MP0003137_abnormal_impulse_conducting0.87067353
86MP0005195_abnormal_posterior_eye0.87034380
87MP0002069_abnormal_eating/drinking_beha0.86749108
88MP0003633_abnormal_nervous_system0.84785117
89MP0008995_early_reproductive_senescence0.84713026
90MP0002752_abnormal_somatic_nervous0.84395383
91MP0003937_abnormal_limbs/digits/tail_de0.84091639
92MP0003861_abnormal_nervous_system0.84091235
93MP0003136_yellow_coat_color0.84046381
94MP0005248_abnormal_Harderian_gland0.83066549
95MP0000678_abnormal_parathyroid_gland0.82967679
96MP0001963_abnormal_hearing_physiology0.81681946
97MP0000049_abnormal_middle_ear0.81148095
98MP0002234_abnormal_pharynx_morphology0.77993512
99MP0008877_abnormal_DNA_methylation0.75280423
100MP0004233_abnormal_muscle_weight0.75250141
101MP0003119_abnormal_digestive_system0.73541957
102MP0004215_abnormal_myocardial_fiber0.71430709
103MP0003631_nervous_system_phenotype0.69598321
104MP0000026_abnormal_inner_ear0.69023111
105MP0003385_abnormal_body_wall0.67101513
106MP0005551_abnormal_eye_electrophysiolog0.67098886
107MP0004133_heterotaxia0.66522989
108MP0004145_abnormal_muscle_electrophysio0.65236777
109MP0008789_abnormal_olfactory_epithelium0.64490020
110MP0005409_darkened_coat_color0.62828823
111MP0002229_neurodegeneration0.62796139
112MP0001664_abnormal_digestion0.62678899
113MP0001299_abnormal_eye_distance/0.60580575
114MP0001177_atelectasis0.60045790
115MP0001943_abnormal_respiration0.58077266
116MP0004742_abnormal_vestibular_system0.57924437
117MP0003634_abnormal_glial_cell0.57744190
118MP0002082_postnatal_lethality0.57632998
119MP0010770_preweaning_lethality0.57632998
120MP0000534_abnormal_ureter_morphology0.57391157
121MP0003938_abnormal_ear_development0.57169419
122MP0010769_abnormal_survival0.56277321
123MP0002876_abnormal_thyroid_physiology0.55560257

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.08861912
2Myokymia (HP:0002411)5.30532288
3Epileptic encephalopathy (HP:0200134)4.74548154
4Focal seizures (HP:0007359)4.58644021
5Visual hallucinations (HP:0002367)4.49886879
6Febrile seizures (HP:0002373)4.29442574
7Progressive cerebellar ataxia (HP:0002073)3.93176145
8Atonic seizures (HP:0010819)3.80214381
9True hermaphroditism (HP:0010459)3.72766992
10Hyperventilation (HP:0002883)3.72382199
11Pancreatic fibrosis (HP:0100732)3.59945414
12Absence seizures (HP:0002121)3.52761879
13Pancreatic cysts (HP:0001737)3.52694897
14Broad-based gait (HP:0002136)3.34825636
15Dialeptic seizures (HP:0011146)3.21197027
16Ankle clonus (HP:0011448)3.06813355
17Abnormality of midbrain morphology (HP:0002418)3.01824400
18Molar tooth sign on MRI (HP:0002419)3.01824400
19Generalized tonic-clonic seizures (HP:0002069)2.97235330
20Pendular nystagmus (HP:0012043)2.96442044
21Impaired vibration sensation in the lower limbs (HP:0002166)2.93240246
22Nephronophthisis (HP:0000090)2.91553624
23Amblyopia (HP:0000646)2.89658073
24Type II lissencephaly (HP:0007260)2.85201052
25Pachygyria (HP:0001302)2.84104290
26Excessive salivation (HP:0003781)2.78267684
27Drooling (HP:0002307)2.78267684
28Epileptiform EEG discharges (HP:0011182)2.77902149
29Limb dystonia (HP:0002451)2.75327777
30Poor eye contact (HP:0000817)2.70807031
31EEG with generalized epileptiform discharges (HP:0011198)2.67160096
32Truncal ataxia (HP:0002078)2.66453522
33Gait imbalance (HP:0002141)2.60797741
34Depression (HP:0000716)2.60498853
35Anxiety (HP:0000739)2.53960570
36Hypsarrhythmia (HP:0002521)2.51443245
37Gaze-evoked nystagmus (HP:0000640)2.50535535
38Intestinal atresia (HP:0011100)2.50433421
39Chronic hepatic failure (HP:0100626)2.47886618
40Progressive macrocephaly (HP:0004481)2.46282579
41Supranuclear gaze palsy (HP:0000605)2.45033350
42Protruding tongue (HP:0010808)2.40410991
43Absent speech (HP:0001344)2.40008108
44Acute necrotizing encephalopathy (HP:0006965)2.36897669
45Abnormality of the renal medulla (HP:0100957)2.35999759
46Mutism (HP:0002300)2.35950301
47Keratoconus (HP:0000563)2.35911575
48Increased corneal curvature (HP:0100692)2.35911575
49Agitation (HP:0000713)2.35098380
50Action tremor (HP:0002345)2.34705822
51Polyphagia (HP:0002591)2.33246738
52Hemiparesis (HP:0001269)2.32538787
53Genetic anticipation (HP:0003743)2.30951790
54Renal cortical cysts (HP:0000803)2.29138374
55Progressive inability to walk (HP:0002505)2.29021136
56Optic nerve hypoplasia (HP:0000609)2.28358599
57Abnormal eating behavior (HP:0100738)2.26750046
58Impaired social interactions (HP:0000735)2.24577169
59Abnormal social behavior (HP:0012433)2.24577169
60Hypothermia (HP:0002045)2.22851629
61Abnormality of the renal cortex (HP:0011035)2.22468429
62Megalencephaly (HP:0001355)2.21430365
63Pheochromocytoma (HP:0002666)2.20689316
64Abnormality of the lower motor neuron (HP:0002366)2.20515121
65Abolished electroretinogram (ERG) (HP:0000550)2.20079961
66Urinary bladder sphincter dysfunction (HP:0002839)2.17530814
67Torticollis (HP:0000473)2.16169644
68Dysdiadochokinesis (HP:0002075)2.15213926
69Congenital primary aphakia (HP:0007707)2.15193671
70Cystic liver disease (HP:0006706)2.15143144
71Aplasia/Hypoplasia of the tongue (HP:0010295)2.14915421
72Sclerocornea (HP:0000647)2.14752297
73Postaxial hand polydactyly (HP:0001162)2.12659490
74Stereotypic behavior (HP:0000733)2.09731021
75Obstructive sleep apnea (HP:0002870)2.09458556
76Hypoplasia of the brainstem (HP:0002365)2.08717933
77Aplasia/Hypoplasia of the brainstem (HP:0007362)2.08717933
78Aplasia/Hypoplasia of the tibia (HP:0005772)2.07236566
79Medial flaring of the eyebrow (HP:0010747)2.06381041
80Nephrogenic diabetes insipidus (HP:0009806)2.05206044
81Abnormal hair whorl (HP:0010721)2.04652974
82Impaired smooth pursuit (HP:0007772)2.04649391
83Focal dystonia (HP:0004373)2.04207167
84Oligodactyly (hands) (HP:0001180)2.04118632
85Occipital encephalocele (HP:0002085)2.03989830
86Poor coordination (HP:0002370)2.03267656
87Decreased central vision (HP:0007663)2.02269356
88Lissencephaly (HP:0001339)2.01261526
89Split foot (HP:0001839)2.00310861
90Anencephaly (HP:0002323)1.99758267
91Inability to walk (HP:0002540)1.99337298
92Fetal akinesia sequence (HP:0001989)1.98822058
93Hepatoblastoma (HP:0002884)1.98659149
94Specific learning disability (HP:0001328)1.97615382
95Abnormality of ocular smooth pursuit (HP:0000617)1.97280869
96Neuroendocrine neoplasm (HP:0100634)1.96748509
97Urinary urgency (HP:0000012)1.96519007
98Papilledema (HP:0001085)1.93019514
99Methylmalonic acidemia (HP:0002912)1.92760900
100Postaxial foot polydactyly (HP:0001830)1.92679147
101Abnormal mitochondria in muscle tissue (HP:0008316)1.92481033
102Attenuation of retinal blood vessels (HP:0007843)1.92193817
103Sleep apnea (HP:0010535)1.90730312
104Acute encephalopathy (HP:0006846)1.90464183
105Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.90070423
106Short tibia (HP:0005736)1.89515048
107Colon cancer (HP:0003003)1.88520664
108Hypoplastic pelvis (HP:0008839)1.88462406
109Congenital stationary night blindness (HP:0007642)1.88437381
110Chorioretinal atrophy (HP:0000533)1.87756169
111Retinal dysplasia (HP:0007973)1.87629662
112Spastic tetraplegia (HP:0002510)1.87055866
113Hypoventilation (HP:0002791)1.85784213
114Dysmetria (HP:0001310)1.84384176
115Abnormal EKG (HP:0003115)1.83933302
116Poor suck (HP:0002033)1.83763044
117Narrow forehead (HP:0000341)1.83141692
118Abnormality of the astrocytes (HP:0100707)1.82411113
119Astrocytoma (HP:0009592)1.82411113
120Mitochondrial inheritance (HP:0001427)1.81793294
121Esotropia (HP:0000565)1.81044275
122Abnormality of binocular vision (HP:0011514)1.79760672
123Diplopia (HP:0000651)1.79760672
124Amyotrophic lateral sclerosis (HP:0007354)1.79641757
125Male pseudohermaphroditism (HP:0000037)1.79188013
126Incomplete penetrance (HP:0003829)1.77805900
127Narrow nasal bridge (HP:0000446)1.77158773
128Bradykinesia (HP:0002067)1.77034945
129Dyskinesia (HP:0100660)1.76831548
130Abnormality of salivation (HP:0100755)1.76729138
131Spinal canal stenosis (HP:0003416)1.76700384
132Abnormality of the labia minora (HP:0012880)1.76485662
133Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.76272825
134Renal hypoplasia (HP:0000089)1.75453933
135Furrowed tongue (HP:0000221)1.75044507
136Spastic gait (HP:0002064)1.74959441
137Failure to thrive in infancy (HP:0001531)1.74556602
138Craniofacial dystonia (HP:0012179)1.73546163
139Congenital hepatic fibrosis (HP:0002612)1.72235409
140Postural instability (HP:0002172)1.68583053
141Abnormal rod and cone electroretinograms (HP:0008323)1.67989521
142Abnormality of vitamin B metabolism (HP:0004340)1.67982387
143Scanning speech (HP:0002168)1.66460764
144Absent rod-and cone-mediated responses on ERG (HP:0007688)1.66192945
145Bony spicule pigmentary retinopathy (HP:0007737)1.66105390
146Prolonged QT interval (HP:0001657)1.65989431
147Abnormality of the corticospinal tract (HP:0002492)1.65616443
148Congenital sensorineural hearing impairment (HP:0008527)1.65028755
149Increased CSF lactate (HP:0002490)1.64865750
150Decreased circulating renin level (HP:0003351)1.64658961
151Impaired vibratory sensation (HP:0002495)1.64082683
152Cerebellar dysplasia (HP:0007033)1.64008232
153Neoplasm of the peripheral nervous system (HP:0100007)1.63802377
154Gait ataxia (HP:0002066)1.62179643
155Lower limb muscle weakness (HP:0007340)1.62051477
156Genital tract atresia (HP:0001827)1.62030813
157Gastroesophageal reflux (HP:0002020)1.61819462
158Vaginal atresia (HP:0000148)1.60649291
159Shoulder girdle muscle weakness (HP:0003547)1.60473634
160Exotropia (HP:0000577)1.60296175

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.86802087
2EPHA44.63666848
3MARK14.24757521
4FRK3.71598735
5MAP3K43.07480001
6CASK3.02323557
7MAP2K72.87317361
8MAP3K92.74304151
9MINK12.73993830
10MAP4K22.53852527
11NTRK22.30543768
12TNIK2.25996458
13MAPK132.18233482
14EPHA32.05067058
15KSR11.78755546
16DAPK21.75591637
17MAP3K121.68094427
18PAK61.65306609
19CSNK1G31.63465154
20TRIM281.61990549
21DAPK11.58483779
22CAMKK21.58021558
23PLK21.57573678
24PRPF4B1.55594319
25BMPR1B1.55047060
26SIK31.50560282
27GRK11.50368069
28CSNK1G11.49475969
29PRKD31.44635809
30CDK51.43341831
31CSNK1A1L1.43294667
32MAP2K41.41448998
33CAMKK11.39706922
34SIK21.37372887
35PRKCG1.28497376
36UHMK11.21386881
37GRK51.20151810
38NTRK11.17820132
39ARAF1.17525054
40DYRK21.16655744
41INSRR1.15143333
42NUAK11.15130003
43KSR21.13890828
44PHKG21.09648383
45PHKG11.09648383
46LATS21.05176051
47FGFR21.04523546
48FES1.02776398
49RIPK41.01359349
50STK38L1.00332057
51DYRK1A1.00272909
52OXSR10.98334646
53AKT30.98276157
54CDK180.96105525
55SGK20.95262696
56CDK140.93954374
57SGK2230.93609374
58SGK4940.93609374
59CAMK2A0.90968226
60DYRK30.87703007
61MKNK20.87524960
62CDK150.87498277
63CAMK10.86280924
64BCKDK0.86124002
65ERBB30.85166453
66CDK190.83910781
67STK390.81499187
68PKN10.81309956
69CAMK2B0.80426338
70MARK20.78830393
71NME10.78550916
72CDK11A0.78131378
73MAP3K20.75292890
74ZAK0.74938465
75BRAF0.74720419
76OBSCN0.72723999
77PTK2B0.71586498
78PAK30.71569577
79PRKCE0.70219732
80FER0.69411852
81TYRO30.67302704
82CSNK1G20.66129601
83PNCK0.65044621
84ADRBK20.63953436
85BCR0.63804426
86RPS6KA20.60450141
87CAMK40.60355016
88CCNB10.59666076
89STK380.57337613
90PINK10.56259943
91RAF10.54934587
92BMPR20.54340467
93SGK10.52429595
94CSNK1A10.52129821
95WNK30.52114297
96PRKCZ0.51508034
97SRPK10.51222389
98SGK30.51199457
99MUSK0.50205036
100WNK40.48954687
101MAP3K60.48408300
102LIMK10.47502894
103CAMK2D0.46179240
104CSNK1D0.45683177
105VRK10.45328198
106PRKCH0.44906171
107EPHB20.44241051
108MAPKAPK50.43948006
109LMTK20.43739431
110PRKD20.42629590
111PASK0.42485025
112PRKG10.42406844
113ADRBK10.41645708
114MAP2K10.41170091
115CDC42BPA0.41161867
116ROCK10.39886932
117PRKAA10.39419166
118DDR20.39394105
119RET0.39391950
120PLK40.39160321
121PRKCI0.39118898
122RPS6KA30.38503906
123HIPK20.38231798
124MAPK100.37622248
125RPS6KA40.37436000
126STK110.37373482
127EIF2AK30.36732144
128BRSK10.36501163
129CDK30.36172042
130TAOK10.36100171
131CAMK2G0.35634287
132PRKACB0.35553916
133PRKACA0.35009205
134YES10.34675450
135FGR0.34203589
136PLK30.33859571
137GRK70.32133075
138MKNK10.31016351
139CSNK1E0.28347934
140RPS6KA50.26343442
141NEK10.24831028

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.75519702
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.17004808
3Synaptic vesicle cycle_Homo sapiens_hsa047213.13529805
4Circadian entrainment_Homo sapiens_hsa047132.82401971
5Olfactory transduction_Homo sapiens_hsa047402.75446622
6GABAergic synapse_Homo sapiens_hsa047272.71848400
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.71332378
8Morphine addiction_Homo sapiens_hsa050322.60810673
9Long-term potentiation_Homo sapiens_hsa047202.59569607
10Amphetamine addiction_Homo sapiens_hsa050312.59386208
11Butanoate metabolism_Homo sapiens_hsa006502.49931134
12Glutamatergic synapse_Homo sapiens_hsa047242.47107696
13Dopaminergic synapse_Homo sapiens_hsa047282.31263654
14Insulin secretion_Homo sapiens_hsa049112.20099244
15Taste transduction_Homo sapiens_hsa047422.15793093
16Cocaine addiction_Homo sapiens_hsa050302.06668279
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02295125
18Serotonergic synapse_Homo sapiens_hsa047261.92293227
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.91970993
20Cholinergic synapse_Homo sapiens_hsa047251.90920293
21Protein export_Homo sapiens_hsa030601.87834476
22Salivary secretion_Homo sapiens_hsa049701.82361733
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.74153342
24Long-term depression_Homo sapiens_hsa047301.67744901
25Renin secretion_Homo sapiens_hsa049241.65313533
26Collecting duct acid secretion_Homo sapiens_hsa049661.63573436
27Oxytocin signaling pathway_Homo sapiens_hsa049211.62709867
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.58934737
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.58264752
30Gap junction_Homo sapiens_hsa045401.57810016
31Calcium signaling pathway_Homo sapiens_hsa040201.55610056
32Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.54694869
33Gastric acid secretion_Homo sapiens_hsa049711.49153237
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.47369868
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.46063344
36Vibrio cholerae infection_Homo sapiens_hsa051101.42751132
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.36243500
38Nitrogen metabolism_Homo sapiens_hsa009101.33326813
39GnRH signaling pathway_Homo sapiens_hsa049121.32319995
40Propanoate metabolism_Homo sapiens_hsa006401.32149385
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.29202604
42Steroid biosynthesis_Homo sapiens_hsa001001.28522785
43Axon guidance_Homo sapiens_hsa043601.28073655
44beta-Alanine metabolism_Homo sapiens_hsa004101.25715618
45cAMP signaling pathway_Homo sapiens_hsa040241.21626283
46Selenocompound metabolism_Homo sapiens_hsa004501.21607372
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.21272725
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17859607
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.11278452
50Linoleic acid metabolism_Homo sapiens_hsa005911.10308799
51Melanogenesis_Homo sapiens_hsa049161.09371602
52Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.07364487
53Cardiac muscle contraction_Homo sapiens_hsa042601.07015115
54Estrogen signaling pathway_Homo sapiens_hsa049151.06862889
55Type II diabetes mellitus_Homo sapiens_hsa049301.06635396
56Oocyte meiosis_Homo sapiens_hsa041141.05140794
57Fatty acid elongation_Homo sapiens_hsa000621.02979710
58ErbB signaling pathway_Homo sapiens_hsa040121.02688143
59Glioma_Homo sapiens_hsa052141.02120147
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99705740
61Tryptophan metabolism_Homo sapiens_hsa003800.97240668
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94718453
63Ether lipid metabolism_Homo sapiens_hsa005650.92822384
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.90154977
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89012378
66Peroxisome_Homo sapiens_hsa041460.88053690
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.87675330
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.87652273
69Basal transcription factors_Homo sapiens_hsa030220.85580637
70Alcoholism_Homo sapiens_hsa050340.85154507
71Alzheimers disease_Homo sapiens_hsa050100.83404756
72Fatty acid metabolism_Homo sapiens_hsa012120.82942735
73Oxidative phosphorylation_Homo sapiens_hsa001900.81573293
74Circadian rhythm_Homo sapiens_hsa047100.81555779
75Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80619817
76Phototransduction_Homo sapiens_hsa047440.79840285
77Dilated cardiomyopathy_Homo sapiens_hsa054140.76332951
78Parkinsons disease_Homo sapiens_hsa050120.73810450
79RNA polymerase_Homo sapiens_hsa030200.73763430
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.72613583
81Caffeine metabolism_Homo sapiens_hsa002320.72166549
82Fanconi anemia pathway_Homo sapiens_hsa034600.71787517
83Wnt signaling pathway_Homo sapiens_hsa043100.71376456
84Primary bile acid biosynthesis_Homo sapiens_hsa001200.69984327
85Glucagon signaling pathway_Homo sapiens_hsa049220.69825508
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.69678592
87Type I diabetes mellitus_Homo sapiens_hsa049400.67829924
88Choline metabolism in cancer_Homo sapiens_hsa052310.64933630
89Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64179514
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.63877659
91MAPK signaling pathway_Homo sapiens_hsa040100.63437168
92Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.62091669
93Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62087973
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.62012784
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61586584
96Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61269993
97Huntingtons disease_Homo sapiens_hsa050160.59885546
98Ras signaling pathway_Homo sapiens_hsa040140.59161887
99Endometrial cancer_Homo sapiens_hsa052130.58763852
100Thyroid hormone synthesis_Homo sapiens_hsa049180.57957977
101Pancreatic secretion_Homo sapiens_hsa049720.57927257
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57503521
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56851413
104Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55538629
105Retinol metabolism_Homo sapiens_hsa008300.55109278
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54608561
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54070836
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.53718576
109Colorectal cancer_Homo sapiens_hsa052100.53715922
110Rap1 signaling pathway_Homo sapiens_hsa040150.53653305
111Basal cell carcinoma_Homo sapiens_hsa052170.50957036
112RNA degradation_Homo sapiens_hsa030180.50466116
113Insulin signaling pathway_Homo sapiens_hsa049100.49753120
114Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49472661
115Chemical carcinogenesis_Homo sapiens_hsa052040.47807689
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47216377
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47076968
118Fatty acid biosynthesis_Homo sapiens_hsa000610.46402393
119Hippo signaling pathway_Homo sapiens_hsa043900.44352307
120Hedgehog signaling pathway_Homo sapiens_hsa043400.44331709
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44250211
122ABC transporters_Homo sapiens_hsa020100.41801759
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.41781923
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41688673
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41261683
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41014439
127Metabolic pathways_Homo sapiens_hsa011000.40978697
128VEGF signaling pathway_Homo sapiens_hsa043700.40504975
129mTOR signaling pathway_Homo sapiens_hsa041500.38737266
130Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38311641
131Ovarian steroidogenesis_Homo sapiens_hsa049130.38025431
132Melanoma_Homo sapiens_hsa052180.37855191
133Renal cell carcinoma_Homo sapiens_hsa052110.36470157
134Fatty acid degradation_Homo sapiens_hsa000710.36324384
135Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35996610
136Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35599891
137Glycerolipid metabolism_Homo sapiens_hsa005610.35514664
138Sphingolipid signaling pathway_Homo sapiens_hsa040710.35435071
139Folate biosynthesis_Homo sapiens_hsa007900.34009776
140Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33644621
141Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33034170
142Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.32139757
143Non-small cell lung cancer_Homo sapiens_hsa052230.31491389
144Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.31253537
145Prion diseases_Homo sapiens_hsa050200.30976126
146Endocytosis_Homo sapiens_hsa041440.30535399
147Regulation of autophagy_Homo sapiens_hsa041400.29862402

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