FAM110C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of female gonad development (GO:2000194)7.07333839
2establishment of skin barrier (GO:0061436)6.84858801
3regulation of water loss via skin (GO:0033561)6.50740953
4keratinization (GO:0031424)6.41508362
5hemidesmosome assembly (GO:0031581)5.43989345
6multicellular organismal water homeostasis (GO:0050891)5.29617098
7intestinal cholesterol absorption (GO:0030299)4.93275281
8cellular glucuronidation (GO:0052695)4.87093905
9water homeostasis (GO:0030104)4.55754530
10glucuronate metabolic process (GO:0019585)4.55349703
11uronic acid metabolic process (GO:0006063)4.55349703
12intestinal absorption (GO:0050892)4.31250636
13keratinocyte differentiation (GO:0030216)4.21092213
14gap junction assembly (GO:0016264)4.19869454
15valine metabolic process (GO:0006573)3.96181233
16interferon-gamma secretion (GO:0072643)3.84161067
17transcytosis (GO:0045056)3.70428395
18calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.69480774
19citrulline biosynthetic process (GO:0019240)3.67054932
20epoxygenase P450 pathway (GO:0019373)3.56313662
21regulation of cholesterol homeostasis (GO:2000188)3.56080798
22flavonoid metabolic process (GO:0009812)3.56004285
23definitive hemopoiesis (GO:0060216)3.55262741
24epidermal cell differentiation (GO:0009913)3.52329250
25keratinocyte development (GO:0003334)3.51893725
26regulation of bile acid biosynthetic process (GO:0070857)3.44229509
27growth hormone receptor signaling pathway (GO:0060396)3.40844709
28bundle of His cell to Purkinje myocyte communication (GO:0086069)3.40346301
29lung lobe morphogenesis (GO:0060463)3.32362016
30mesodermal cell differentiation (GO:0048333)3.31234474
31chemical homeostasis within a tissue (GO:0048875)3.28967355
32epidermis development (GO:0008544)3.28331834
33positive regulation of Cdc42 GTPase activity (GO:0043089)3.21903033
34intestinal epithelial cell development (GO:0060576)3.21601582
35molting cycle (GO:0042303)3.19816453
36hair cycle (GO:0042633)3.19816453
37regulation of keratinocyte proliferation (GO:0010837)3.15619702
38digestion (GO:0007586)3.15015823
39piRNA metabolic process (GO:0034587)3.12818891
40regulation of keratinocyte differentiation (GO:0045616)3.11093233
41drug transmembrane transport (GO:0006855)3.10948513
42hepatocyte apoptotic process (GO:0097284)3.07066034
43regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.04958385
44cell adhesion mediated by integrin (GO:0033627)3.02988183
45surfactant homeostasis (GO:0043129)2.99846278
46polarized epithelial cell differentiation (GO:0030859)2.98679950
47negative regulation of smooth muscle cell differentiation (GO:0051151)2.95154763
48diterpenoid biosynthetic process (GO:0016102)2.92151898
49regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.90954800
50regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.90415266
51protein retention in ER lumen (GO:0006621)2.87810430
52auditory receptor cell differentiation (GO:0042491)2.86459892
53exogenous drug catabolic process (GO:0042738)2.84526733
54maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.84119380
55notochord development (GO:0030903)2.83725134
56negative regulation of epidermal cell differentiation (GO:0045605)2.83714783
57cellular response to growth hormone stimulus (GO:0071378)2.82970508
58regulation of transforming growth factor beta1 production (GO:0032908)2.82664487
59phenylpropanoid metabolic process (GO:0009698)2.82376752
60intermediate filament organization (GO:0045109)2.81955396
61maintenance of gastrointestinal epithelium (GO:0030277)2.81550887
62sulfur amino acid catabolic process (GO:0000098)2.78991023
63drug metabolic process (GO:0017144)2.77274919
64phosphatidylserine acyl-chain remodeling (GO:0036150)2.76924950
65ventricular cardiac muscle cell action potential (GO:0086005)2.76265487
66Leydig cell differentiation (GO:0033327)2.72747332
67negative regulation of keratinocyte proliferation (GO:0010839)2.72205755
68bile acid and bile salt transport (GO:0015721)2.69251921
69regulation of cardioblast differentiation (GO:0051890)2.68967367
70oocyte development (GO:0048599)2.68728707
71ectoderm development (GO:0007398)2.67780038
72positive regulation of epidermis development (GO:0045684)2.67537790
73O-glycan processing (GO:0016266)2.67151123
74wound healing, spreading of cells (GO:0044319)2.66940546
75regulation of complement activation (GO:0030449)2.66630201
76histone H2A monoubiquitination (GO:0035518)2.65873392
77mitotic chromosome condensation (GO:0007076)2.65778905
78skin morphogenesis (GO:0043589)2.64906482
79regulation of protein activation cascade (GO:2000257)2.64616871
80regulation of epidermal cell differentiation (GO:0045604)2.64376525
81regulation of transforming growth factor beta2 production (GO:0032909)2.62691800
82desmosome organization (GO:0002934)2.61938623
83exocrine pancreas development (GO:0031017)2.61867703
84decidualization (GO:0046697)2.59834965
85peptide cross-linking (GO:0018149)2.59705795
86mitotic sister chromatid cohesion (GO:0007064)2.59671540
87urea metabolic process (GO:0019627)2.59332401
88regulation of apoptotic process involved in morphogenesis (GO:1902337)2.59174636
89cysteine metabolic process (GO:0006534)2.58726236
90epithelial cell-cell adhesion (GO:0090136)2.58572554
91vitamin A metabolic process (GO:0006776)2.58332666
92mitochondrial calcium ion transport (GO:0006851)2.57756098
93phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.57105497
94regulation of proton transport (GO:0010155)2.56690063
95erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.56580220
96L-phenylalanine metabolic process (GO:0006558)2.56580220
97COPI coating of Golgi vesicle (GO:0048205)2.56202644
98Golgi transport vesicle coating (GO:0048200)2.56202644
99negative regulation of complement activation (GO:0045916)2.56073729
100negative regulation of protein activation cascade (GO:2000258)2.56025166
101somatic stem cell division (GO:0048103)2.55745840
102branching involved in mammary gland duct morphogenesis (GO:0060444)2.55664885
103mammary gland alveolus development (GO:0060749)2.55330501
104keratinocyte proliferation (GO:0043616)2.54980106
105positive regulation of epidermal cell differentiation (GO:0045606)2.54206130
106regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.53048560
107cell-substrate junction assembly (GO:0007044)2.50509799
108gland morphogenesis (GO:0022612)2.49273579
109lateral sprouting from an epithelium (GO:0060601)2.48753574
110cellular response to vitamin (GO:0071295)2.48330263
111cell-cell junction assembly (GO:0007043)2.47972866
112tight junction assembly (GO:0070830)2.47525168
113membrane budding (GO:0006900)2.47361345
114terpenoid biosynthetic process (GO:0016114)2.47194776
115bile acid metabolic process (GO:0008206)2.46126014
116androgen metabolic process (GO:0008209)2.45066810
117negative regulation of epidermis development (GO:0045683)2.45034020
118peptide catabolic process (GO:0043171)2.43626317
119regulation of epidermis development (GO:0045682)2.43532871
120regulation of transforming growth factor beta production (GO:0071634)2.43520784
121cellular response to arsenic-containing substance (GO:0071243)2.42991921
122regulation of endothelial cell chemotaxis (GO:2001026)2.41755258
123drug transport (GO:0015893)2.41724422
124atrioventricular valve morphogenesis (GO:0003181)2.41467874
125endosome to pigment granule transport (GO:0043485)2.40384654
126endosome to melanosome transport (GO:0035646)2.40384654
127urea cycle (GO:0000050)2.40255517
128muscle cell migration (GO:0014812)2.39004756
129regulation of RIG-I signaling pathway (GO:0039535)2.38635780
130folic acid transport (GO:0015884)2.37296428
131cardiac right ventricle morphogenesis (GO:0003215)2.37238312
132L-phenylalanine catabolic process (GO:0006559)2.37213346
133erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.37213346
134smooth muscle tissue development (GO:0048745)2.36371232
135renal system process involved in regulation of blood volume (GO:0001977)2.36351079
136positive regulation of p38MAPK cascade (GO:1900745)2.35854695
137ER overload response (GO:0006983)2.35190517
138establishment of planar polarity (GO:0001736)2.34791558
139establishment of tissue polarity (GO:0007164)2.34791558
140low-density lipoprotein particle clearance (GO:0034383)2.34377324
141digestive system process (GO:0022600)2.34316334
142apical protein localization (GO:0045176)2.33339470
143regulation of hair cycle (GO:0042634)2.33028986
144positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.32294248
145regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.31916515
146lung vasculature development (GO:0060426)2.31622301
147epithelial cell maturation (GO:0002070)2.31531493
148antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.31162695
149positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.30970375
150ribosomal small subunit assembly (GO:0000028)2.30286993
151fibroblast migration (GO:0010761)2.30014123
152regulation of heart rate by cardiac conduction (GO:0086091)2.29898682
153negative regulation of protein autophosphorylation (GO:0031953)2.29291708
154AMP metabolic process (GO:0046033)2.28860144
155retinal metabolic process (GO:0042574)2.25688306
156epithelial structure maintenance (GO:0010669)2.25012670
157regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.24519919
158diacylglycerol metabolic process (GO:0046339)2.23253410
159regulation of acrosome reaction (GO:0060046)2.21997428
160negative regulation of reproductive process (GO:2000242)2.20418597
161purine nucleotide salvage (GO:0032261)2.20397818
162branching involved in salivary gland morphogenesis (GO:0060445)2.19130378
163regulation of sister chromatid cohesion (GO:0007063)2.18944515
164drug catabolic process (GO:0042737)2.17067998
165positive regulation of epithelial to mesenchymal transition (GO:0010718)2.16597574
166negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.15225043
167apoptotic cell clearance (GO:0043277)2.14131353
168angiotensin maturation (GO:0002003)2.13335683
169face development (GO:0060324)2.12617703
170histone H2A ubiquitination (GO:0033522)2.12199165
171UDP-N-acetylglucosamine metabolic process (GO:0006047)2.11594074
172oocyte maturation (GO:0001556)2.09298646
173modified amino acid transport (GO:0072337)2.08986218
174myoblast migration (GO:0051451)2.08839020
175toxin transport (GO:1901998)2.07265953
176cellular response to vitamin D (GO:0071305)2.06509392
177negative regulation of smooth muscle cell migration (GO:0014912)2.06435910

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.09540489
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.74095229
3ESR1_21235772_ChIP-Seq_MCF-7_Human2.93246639
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.88423982
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.74583864
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.67139938
7AR_21909140_ChIP-Seq_LNCAP_Human2.65024308
8CLOCK_20551151_ChIP-Seq_293T_Human2.50668627
9RARG_19884340_ChIP-ChIP_MEFs_Mouse2.47566932
10STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.33954224
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.26856177
12TRIM28_21343339_ChIP-Seq_HEK293_Human2.26661161
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.23358725
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.22899223
15PPAR_26484153_Chip-Seq_NCI-H1993_Human2.14377324
16* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.13318822
17GATA4_25053715_ChIP-Seq_YYC3_Human2.12935433
18FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.09624240
19GATA6_25053715_ChIP-Seq_YYC3_Human2.06017577
20* SOX2_20726797_ChIP-Seq_SW620_Human2.04662523
21KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.01856332
22SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.95767401
23SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.95767401
24FOXO3_23340844_ChIP-Seq_DLD1_Human1.95607281
25RXR_22158963_ChIP-Seq_LIVER_Mouse1.95013638
26AHR_22903824_ChIP-Seq_MCF-7_Human1.93055378
27PPARA_22158963_ChIP-Seq_LIVER_Mouse1.92056864
28ATF3_27146783_Chip-Seq_COLON_Human1.89452915
29FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.88402839
30SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.84030552
31SCL_19346495_ChIP-Seq_HPC-7_Human1.83543994
32TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82866857
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.79692079
34GATA2_21666600_ChIP-Seq_HMVEC_Human1.74978285
35CDX2_20551321_ChIP-Seq_CACO-2_Human1.74742273
36EGR1_19374776_ChIP-ChIP_THP-1_Human1.70448432
37* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.62736456
38ARNT_22903824_ChIP-Seq_MCF-7_Human1.59602439
39ZNF263_19887448_ChIP-Seq_K562_Human1.57162155
40LXR_22158963_ChIP-Seq_LIVER_Mouse1.56346913
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.55186925
42* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.49746874
43FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.49622812
44HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.49191784
45CJUN_26792858_Chip-Seq_BT549_Human1.48298941
46RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.48233370
47FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.47225713
48SALL4_18804426_ChIP-ChIP_XEN_Mouse1.47168271
49* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.46753086
50IRF8_22096565_ChIP-ChIP_GC-B_Human1.46534026
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45596751
52CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.45031672
53TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44826141
54* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42049600
55ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.41067618
56PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.39868488
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.33293478
58TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.33280081
59RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31867219
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.31818828
61SOX9_24532713_ChIP-Seq_HFSC_Mouse1.31735849
62KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28943753
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.26449918
64CDX2_22108803_ChIP-Seq_LS180_Human1.25984538
65JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25086383
66ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.24925523
67FOXA1_25552417_ChIP-Seq_VCAP_Human1.23991818
68RACK7_27058665_Chip-Seq_MCF-7_Human1.23819113
69TP53_18474530_ChIP-ChIP_U2OS_Human1.23371973
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.22993937
71KLF5_25053715_ChIP-Seq_YYC3_Human1.22671233
72FOXA2_19822575_ChIP-Seq_HepG2_Human1.21333211
73RUNX1_27514584_Chip-Seq_MCF-7_Human1.20835261
74GATA3_24758297_ChIP-Seq_MCF-7_Human1.20098746
75P63_26484246_Chip-Seq_KERATINOCYTES_Human1.19650789
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15708044
77ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11704795
78CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10270841
79GATA2_19941826_ChIP-Seq_K562_Human1.10130766
80ELK3_25401928_ChIP-Seq_HUVEC_Human1.09883085
81NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.09474299
82EGR1_23403033_ChIP-Seq_LIVER_Mouse1.09131481
83* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.07257779
84STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06058059
85* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04177067
86TCF4_18268006_ChIP-ChIP_LS174T_Human1.04163155
87STAT6_21828071_ChIP-Seq_BEAS2B_Human1.03208083
88SMAD3_21741376_ChIP-Seq_HESCs_Human1.02955868
89FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.01500010
90BRD4_25478319_ChIP-Seq_HGPS_Human1.00559448
91ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99641532
92EP300_21415370_ChIP-Seq_HL-1_Mouse0.99464783
93RXR_22108803_ChIP-Seq_LS180_Human0.98290357
94FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.97805307
95NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.97411770
96FOXM1_23109430_ChIP-Seq_U2OS_Human0.96682158
97NRF2_20460467_ChIP-Seq_MEFs_Mouse0.95942955
98NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.95942955
99FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95441245
100JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94207517
101EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.92886074
102ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.92032116
103GATA1_19941826_ChIP-Seq_K562_Human0.91871645
104CHD1_26751641_Chip-Seq_LNCaP_Human0.91209313
105RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.90230673
106BP1_19119308_ChIP-ChIP_Hs578T_Human0.89767100
107GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.89673414
108Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.88330651
109SALL1_21062744_ChIP-ChIP_HESCs_Human0.87637289
110* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.87136589
111TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.87070273
112IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.87016153
113UBF1/2_26484160_Chip-Seq_HMECs_Human0.85853689
114EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.82976684
115* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.82581103
116TP63_23658742_ChIP-Seq_EP156T_Human0.82145835
117HNF4A_19822575_ChIP-Seq_HepG2_Human0.82060956
118ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.81817755
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.81397830
120POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80789105
121KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.80784681
122AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.80439022
123* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.80413813
124RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.79839463
125TP53_16413492_ChIP-PET_HCT116_Human0.74942112
126BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74127351
127PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.74044783
128ELF5_23300383_ChIP-Seq_T47D_Human0.71839050
129* TCF4_22108803_ChIP-Seq_LS180_Human0.71458768
130NR3C1_21868756_ChIP-Seq_MCF10A_Human0.71163848
131CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.67679683
132SMAD_19615063_ChIP-ChIP_OVARY_Human0.66927459
133* PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.65293446
134SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.65100196
135TP63_22573176_ChIP-Seq_HFKS_Human0.65059580
136TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.64424189
137CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.63698633

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001666_abnormal_nutrient_absorption3.27049198
2MP0010234_abnormal_vibrissa_follicle3.21180085
3MP0002877_abnormal_melanocyte_morpholog2.70344426
4MP0004264_abnormal_extraembryonic_tissu2.64177106
5MP0010352_gastrointestinal_tract_polyps2.54475231
6MP0006054_spinal_hemorrhage2.53341193
7MP0005360_urolithiasis2.53131735
8MP0003705_abnormal_hypodermis_morpholog2.51991315
9MP0003718_maternal_effect2.51984549
10MP0003195_calcinosis2.24752886
11MP0002254_reproductive_system_inflammat2.17343249
12MP0002060_abnormal_skin_morphology1.96116140
13MP0000490_abnormal_crypts_of1.90757070
14MP0005365_abnormal_bile_salt1.89646019
15MP0005409_darkened_coat_color1.87819113
16MP0004782_abnormal_surfactant_physiolog1.86963290
17MP0003453_abnormal_keratinocyte_physiol1.84884938
18MP0003283_abnormal_digestive_organ1.84759845
19MP0008004_abnormal_stomach_pH1.84670924
20MP0003566_abnormal_cell_adhesion1.83740784
21MP0009780_abnormal_chondrocyte_physiolo1.82959956
22MP0010386_abnormal_urinary_bladder1.82397993
23MP0005023_abnormal_wound_healing1.71930296
24MP0002138_abnormal_hepatobiliary_system1.67899910
25MP0004147_increased_porphyrin_level1.65003630
26MP0008438_abnormal_cutaneous_collagen1.64867988
27MP0002796_impaired_skin_barrier1.62429692
28MP0009384_cardiac_valve_regurgitation1.59544339
29MP0005083_abnormal_biliary_tract1.56256141
30MP0003941_abnormal_skin_development1.53707190
31MP0000566_synostosis1.52818887
32MP0008875_abnormal_xenobiotic_pharmacok1.50206904
33MP0002139_abnormal_hepatobiliary_system1.47203603
34MP0001346_abnormal_lacrimal_gland1.46696897
35MP0005275_abnormal_skin_tensile1.45851995
36MP0010368_abnormal_lymphatic_system1.45536732
37MP0005220_abnormal_exocrine_pancreas1.43779482
38MP0001849_ear_inflammation1.42362908
39MP0000537_abnormal_urethra_morphology1.41405150
40MP0003300_gastrointestinal_ulcer1.41115200
41MP0005395_other_phenotype1.41098736
42MP0005085_abnormal_gallbladder_physiolo1.40734297
43MP0010155_abnormal_intestine_physiology1.37762810
44MP0000465_gastrointestinal_hemorrhage1.36685128
45MP0001216_abnormal_epidermal_layer1.34258912
46MP0004043_abnormal_pH_regulation1.32636291
47MP0005084_abnormal_gallbladder_morpholo1.29798564
48MP0003191_abnormal_cellular_cholesterol1.28702783
49MP0003693_abnormal_embryo_hatching1.26729755
50MP0001881_abnormal_mammary_gland1.21992468
51MP0004272_abnormal_basement_membrane1.20998950
52MP0005408_hypopigmentation1.20383209
53MP0000477_abnormal_intestine_morphology1.19978469
54MP0003866_abnormal_defecation1.18793755
55MP0005501_abnormal_skin_physiology1.18414867
56MP0000858_altered_metastatic_potential1.17563990
57MP0002909_abnormal_adrenal_gland1.16683351
58MP0005332_abnormal_amino_acid1.15139414
59MP0001915_intracranial_hemorrhage1.10733318
60MP0004185_abnormal_adipocyte_glucose1.10580516
61MP0002098_abnormal_vibrissa_morphology1.10224318
62MP0010678_abnormal_skin_adnexa1.09687536
63MP0002876_abnormal_thyroid_physiology1.06499728
64MP0009840_abnormal_foam_cell1.06290533
65MP0000467_abnormal_esophagus_morphology1.06023249
66MP0000613_abnormal_salivary_gland1.04360833
67MP0000678_abnormal_parathyroid_gland1.04076213
68MP0001664_abnormal_digestion1.03819994
69MP0010329_abnormal_lipoprotein_level1.02953679
70MP0004957_abnormal_blastocyst_morpholog1.02795879
71MP0009053_abnormal_anal_canal1.02295562
72MP0004947_skin_inflammation1.00485821
73MP0004808_abnormal_hematopoietic_stem0.99928587
74MP0003183_abnormal_peptide_metabolism0.98412485
75MP0003045_fibrosis0.97675604
76MP0002295_abnormal_pulmonary_circulatio0.97606900
77MP0003011_delayed_dark_adaptation0.97239729
78MP0010030_abnormal_orbit_morphology0.95534438
79MP0009643_abnormal_urine_homeostasis0.95414511
80MP0005397_hematopoietic_system_phenotyp0.94115452
81MP0001545_abnormal_hematopoietic_system0.94115452
82MP0008007_abnormal_cellular_replicative0.92679994
83MP0003186_abnormal_redox_activity0.92465655
84MP0003699_abnormal_female_reproductive0.92344514
85MP0003656_abnormal_erythrocyte_physiolo0.91778475
86MP0001958_emphysema0.90405163
87MP0009931_abnormal_skin_appearance0.89767543
88MP0000377_abnormal_hair_follicle0.89214245
89MP0002396_abnormal_hematopoietic_system0.88576629
90MP0004381_abnormal_hair_follicle0.88007274
91MP0010771_integument_phenotype0.87654503
92MP0005451_abnormal_body_composition0.87329257
93MP0001851_eye_inflammation0.87234831
94MP0001119_abnormal_female_reproductive0.86807149
95MP0000579_abnormal_nail_morphology0.86129517
96MP0003868_abnormal_feces_composition0.85670371
97MP0001765_abnormal_ion_homeostasis0.85319717
98MP0001873_stomach_inflammation0.85285521
99MP0003315_abnormal_perineum_morphology0.85202326
100MP0003252_abnormal_bile_duct0.84969253
101MP0000462_abnormal_digestive_system0.84747828
102MP0002234_abnormal_pharynx_morphology0.84450148
103MP0002282_abnormal_trachea_morphology0.84139725
104MP0003091_abnormal_cell_migration0.83803008
105MP0004019_abnormal_vitamin_homeostasis0.83658873
106MP0003878_abnormal_ear_physiology0.82297133
107MP0005377_hearing/vestibular/ear_phenot0.82297133
108MP0005666_abnormal_adipose_tissue0.81494718
109MP0000538_abnormal_urinary_bladder0.80946300
110MP0005464_abnormal_platelet_physiology0.80751586
111MP0004885_abnormal_endolymph0.79991330
112MP0000367_abnormal_coat/_hair0.79772370
113MP0002089_abnormal_postnatal_growth/wei0.78874343
114MP0001756_abnormal_urination0.78596103
115MP0002896_abnormal_bone_mineralization0.78483637
116MP0000383_abnormal_hair_follicle0.77047180
117MP0001661_extended_life_span0.76712619
118MP0005076_abnormal_cell_differentiation0.76371674
119MP0000647_abnormal_sebaceous_gland0.75919040
120MP0003936_abnormal_reproductive_system0.75357234
121MP0009764_decreased_sensitivity_to0.74322255
122MP0001663_abnormal_digestive_system0.74104343
123MP0000762_abnormal_tongue_morphology0.73857817
124MP0000427_abnormal_hair_cycle0.73459174
125MP0003279_aneurysm0.73219606
126MP0000598_abnormal_liver_morphology0.71682182
127MP0002118_abnormal_lipid_homeostasis0.71677049
128MP0000470_abnormal_stomach_morphology0.70801021
129MP0001191_abnormal_skin_condition0.70211137
130MP0000627_abnormal_mammary_gland0.69946963
131MP0002249_abnormal_larynx_morphology0.69861089
132MP0005248_abnormal_Harderian_gland0.69306628
133MP0003937_abnormal_limbs/digits/tail_de0.68996400
134MP0000003_abnormal_adipose_tissue0.65490958
135MP0002136_abnormal_kidney_physiology0.63323038
136MP0003638_abnormal_response/metabolism_0.62879516
137MP0005670_abnormal_white_adipose0.61412222
138MP0005636_abnormal_mineral_homeostasis0.59136039
139MP0000013_abnormal_adipose_tissue0.58825666
140MP0008872_abnormal_physiological_respon0.58050435
141MP0001501_abnormal_sleep_pattern0.57988766
142MP0003943_abnormal_hepatobiliary_system0.56278113
143MP0005257_abnormal_intraocular_pressure0.55923755
144MP0001340_abnormal_eyelid_morphology0.54360573
145MP0003950_abnormal_plasma_membrane0.53454825
146MP0005375_adipose_tissue_phenotype0.51497108

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of nail color (HP:0100643)6.67487016
2Palmoplantar hyperkeratosis (HP:0000972)5.03807081
3Palmar hyperkeratosis (HP:0010765)4.73987666
4Thick nail (HP:0001805)4.31442195
5Right ventricular cardiomyopathy (HP:0011663)4.18590197
6Atrophic scars (HP:0001075)3.97438895
7Milia (HP:0001056)3.97219587
8Hypotrichosis (HP:0001006)3.70752249
9Onycholysis (HP:0001806)3.65366714
10Ileus (HP:0002595)3.52758474
11Pili torti (HP:0003777)3.50631056
12Abnormality of secondary sexual hair (HP:0009888)3.39892532
13Abnormality of the axillary hair (HP:0100134)3.39892532
14Fragile skin (HP:0001030)3.23483110
15Corneal erosion (HP:0200020)3.17766361
16Oral leukoplakia (HP:0002745)3.17761326
17Fragile nails (HP:0001808)3.15786970
18Hyperactive renin-angiotensin system (HP:0000841)3.14410771
19Protrusio acetabuli (HP:0003179)3.08249296
20Male infertility (HP:0003251)2.96925682
21Congenital ichthyosiform erythroderma (HP:0007431)2.96745905
22Ankle contracture (HP:0006466)2.91151945
23Sparse eyelashes (HP:0000653)2.88789172
24Abnormality of monocarboxylic acid metabolism (HP:0010996)2.86305286
25Abnormality of the distal phalanges of the toes (HP:0010182)2.81453016
26Malnutrition (HP:0004395)2.79120988
27Ridged nail (HP:0001807)2.78788561
28Absent eyelashes (HP:0000561)2.69628598
29Hypoplasia of the uterus (HP:0000013)2.69280369
30Rectal prolapse (HP:0002035)2.68541189
31Conjugated hyperbilirubinemia (HP:0002908)2.64447463
32Premature rupture of membranes (HP:0001788)2.63397888
33Curly hair (HP:0002212)2.58944047
34Erythema (HP:0010783)2.58066108
35Amelogenesis imperfecta (HP:0000705)2.54303763
36Spondylolisthesis (HP:0003302)2.53244161
37Aortic dissection (HP:0002647)2.51917606
38Alopecia of scalp (HP:0002293)2.51853615
39Cutaneous melanoma (HP:0012056)2.47062413
40Abnormal platelet function (HP:0011869)2.47058665
41Impaired platelet aggregation (HP:0003540)2.47058665
42Septate vagina (HP:0001153)2.46979504
43Abnormality of the salivary glands (HP:0010286)2.46390023
44Abnormality of permanent molar morphology (HP:0011071)2.45731377
45Abnormality of the dental root (HP:0006486)2.45731377
46Taurodontia (HP:0000679)2.45731377
47Epidermoid cyst (HP:0200040)2.42092159
48Thrombocytosis (HP:0001894)2.39581032
49Palmoplantar keratoderma (HP:0000982)2.37450059
50Lip pit (HP:0100267)2.37421445
51Increased mean platelet volume (HP:0011877)2.36716208
52Erythroderma (HP:0001019)2.36381685
53Follicular hyperkeratosis (HP:0007502)2.34199400
54Cervical subluxation (HP:0003308)2.31361308
55Premature ovarian failure (HP:0008209)2.31106627
56Blepharitis (HP:0000498)2.29956887
57Aortic aneurysm (HP:0004942)2.29953565
58Advanced eruption of teeth (HP:0006288)2.29410093
59Pterygium (HP:0001059)2.27389866
60Abnormality of the dental pulp (HP:0006479)2.26480425
61Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.25716613
62Shallow orbits (HP:0000586)2.22546250
63Abnormality of molar (HP:0011077)2.20141374
64Abnormality of molar morphology (HP:0011070)2.20141374
65Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.19910091
66Cortical dysplasia (HP:0002539)2.19198889
67Fat malabsorption (HP:0002630)2.19081672
68Abnormality of chloride homeostasis (HP:0011422)2.16914129
69Vascular calcification (HP:0004934)2.16881697
70Absent hair (HP:0002298)2.16108722
71Abnormal hemoglobin (HP:0011902)2.15903744
72Hypoplastic labia majora (HP:0000059)2.15396199
73Stenosis of the external auditory canal (HP:0000402)2.15040026
74Micronodular cirrhosis (HP:0001413)2.14669298
75Short nail (HP:0001799)2.14611556
76Abnormal hair laboratory examination (HP:0003328)2.13868258
77Secondary amenorrhea (HP:0000869)2.11406496
78Intrahepatic cholestasis (HP:0001406)2.09299226
79Thin bony cortex (HP:0002753)2.09271891
80Complement deficiency (HP:0004431)2.09168489
81Aplasia involving bones of the extremities (HP:0009825)2.08309418
82Aplasia involving bones of the upper limbs (HP:0009823)2.08309418
83Aplasia of the phalanges of the hand (HP:0009802)2.08309418
84Oligodontia (HP:0000677)2.07756552
85Natal tooth (HP:0000695)2.07383820
86Acanthosis nigricans (HP:0000956)2.06713065
87Osteolytic defects of the hand bones (HP:0009699)2.06463166
88Osteolytic defects of the phalanges of the hand (HP:0009771)2.06463166
89Parakeratosis (HP:0001036)2.06032873
90Selective tooth agenesis (HP:0001592)2.04797987
91Hyperaldosteronism (HP:0000859)2.04115957
92Abnormality of glutamine family amino acid metabolism (HP:0010902)2.02797702
93Arterial tortuosity (HP:0005116)2.02753187
94Abnormal platelet volume (HP:0011876)2.01979583
95Abnormality of the heme biosynthetic pathway (HP:0010472)2.01931519
96Insulin resistance (HP:0000855)2.00949376
97Abnormality of the labia majora (HP:0012881)2.00910366
98Abnormal blistering of the skin (HP:0008066)2.00400557
99Labial hypoplasia (HP:0000066)2.00198175
100Aplastic anemia (HP:0001915)1.99124681
101Flat acetabular roof (HP:0003180)1.99065287
102Plantar hyperkeratosis (HP:0007556)1.98978996
103Abnormality of the 2nd finger (HP:0004100)1.97932142
104Dehydration (HP:0001944)1.96037356
105Woolly hair (HP:0002224)1.96028272
106Glomerulosclerosis (HP:0000096)1.95491224
107Sparse scalp hair (HP:0002209)1.94737022
108Myositis (HP:0100614)1.94694632
109Radial bowing (HP:0002986)1.94089141
110Abnormality of aromatic amino acid family metabolism (HP:0004338)1.93374286
111Abnormality of renin-angiotensin system (HP:0000847)1.91941379
112Aplasia/hypoplasia of the uterus (HP:0008684)1.91050243
113Acute myeloid leukemia (HP:0004808)1.90695914
114Insulin-resistant diabetes mellitus (HP:0000831)1.90212341
115Focal segmental glomerulosclerosis (HP:0000097)1.89436807
116Vascular tortuosity (HP:0004948)1.88538496
117Nail dystrophy (HP:0008404)1.86453891
118Hydroxyprolinuria (HP:0003080)1.85833322
119Abnormality of proline metabolism (HP:0010907)1.85833322
120Entropion (HP:0000621)1.84939165
121Esophageal varix (HP:0002040)1.84573649
122Hyperkalemia (HP:0002153)1.84544014
123Gastrointestinal dysmotility (HP:0002579)1.84195147
124Glomerulonephritis (HP:0000099)1.82317822
125Hypobetalipoproteinemia (HP:0003563)1.82291978
126Hypohidrosis (HP:0000966)1.82193171
127Myocardial infarction (HP:0001658)1.81980735
128Decreased circulating renin level (HP:0003351)1.81775030
129Interstitial pulmonary disease (HP:0006530)1.80668758
130Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.80590317
131Autoimmune thrombocytopenia (HP:0001973)1.79932793
132Acanthocytosis (HP:0001927)1.79090282
133Esophageal atresia (HP:0002032)1.78419144
134Prolonged partial thromboplastin time (HP:0003645)1.78314487
135Abnormality of the nasal septum (HP:0000419)1.76721550
136Bowed forearm bones (HP:0003956)1.76613433
137Bowing of the arm (HP:0006488)1.76613433
138Ectropion (HP:0000656)1.76607317
139Abdominal distention (HP:0003270)1.76236897
140Deep venous thrombosis (HP:0002625)1.75484622
141Abnormal biliary tract morphology (HP:0012440)1.75045046
142Hypoplasia of dental enamel (HP:0006297)1.74867676
143Hypoplastic female external genitalia (HP:0012815)1.73930783
144Decreased subcutaneous fat (HP:0001002)1.73540758
145Popliteal pterygium (HP:0009756)1.73531081
146Infertility (HP:0000789)1.73494524
147Hypertriglyceridemia (HP:0002155)1.73278838
148Abnormality of carpal bone ossification (HP:0006257)1.73226522
149Conical tooth (HP:0000698)1.73182780
150Pancreatitis (HP:0001733)1.72453128
151Anonychia (HP:0001798)1.71467679
152Mitral stenosis (HP:0001718)1.71148776
153Cardiovascular calcification (HP:0011915)1.71104630
154Orchitis (HP:0100796)1.71085481
155Steatorrhea (HP:0002570)1.71080979
156Abnormality of cochlea (HP:0000375)1.70603049
157Nephritis (HP:0000123)1.70474460
158Aneurysm (HP:0002617)1.70213154
159Hypodontia (HP:0000668)1.69708906
160Increased density of long bones (HP:0006392)1.69575554
161Abnormality of the gastric mucosa (HP:0004295)1.67853271
162Abnormality of the distal phalanx of the thumb (HP:0009617)1.67444506
163Peritonitis (HP:0002586)1.66256315
164Beaking of vertebral bodies (HP:0004568)1.62642705
165Increased connective tissue (HP:0009025)1.62099787
166Abnormality of the labia (HP:0000058)1.61905199
167Mesangial abnormality (HP:0001966)1.61257579
168Ureteral stenosis (HP:0000071)1.60797014
169Subacute progressive viral hepatitis (HP:0006572)1.60276316

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.14010195
2STK244.06414798
3EPHA23.64235197
4LATS13.33860084
5MST1R2.99611080
6MAP3K122.92988615
7ERN12.65109734
8RPS6KB22.62202605
9MAPKAPK32.58737388
10FRK2.42442086
11TAOK32.35690799
12MAP3K22.34858771
13MAP3K62.18009241
14STK102.13952340
15TRIB32.08457081
16STK392.06886682
17TGFBR11.95933758
18CDK81.89403366
19MAPKAPK51.82613523
20TRPM71.81538551
21EPHA31.78074778
22MAP3K31.76495171
23LRRK21.73707865
24ERBB41.70753938
25MOS1.63563537
26MST41.58436612
27AKT31.55620719
28MAP2K21.55377194
29BCR1.53009135
30EPHB11.51145518
31LMTK21.46091661
32MAP3K91.43693437
33ACVR1B1.41134185
34MET1.38944857
35PKN21.36010577
36FER1.35794100
37STK31.32414220
38LATS21.30455124
39CASK1.25486734
40EPHB21.24599883
41TTK1.20700943
42NEK91.19699752
43CDK61.14260030
44BCKDK1.10315624
45JAK31.08730855
46STK38L1.07914899
47PTK61.05099831
48NEK61.03664650
49FLT31.01764635
50BMPR1B1.01747909
51PTK20.99135130
52PRKG20.98712078
53KSR20.97446595
54EIF2AK30.97414093
55MELK0.96252183
56PIK3CA0.96084471
57PDK20.95237905
58TIE10.94964493
59TNIK0.94473498
60MAP2K10.94463662
61MAP3K80.92852341
62RET0.88699285
63ERBB30.87511183
64TRIM280.86451848
65MATK0.85107211
66CDK90.85004776
67TTN0.83303553
68RIPK10.82379326
69NLK0.80583941
70PAK20.79583616
71FGFR10.78832780
72NME10.78243409
73FGFR20.76219560
74PDGFRA0.75555290
75AURKB0.74920329
76MAPK110.74689212
77RPS6KA40.74206055
78BRSK20.73937760
79FGFR40.72216410
80PDGFRB0.70647956
81HIPK20.70603903
82PRKCE0.70402745
83PIM20.70268824
84SIK10.69917077
85PBK0.69023997
86OXSR10.68780371
87BMPR20.68081515
88PRKD30.67856252
89TGFBR20.67255393
90SIK30.65965887
91PAK40.64949201
92TAOK10.64069440
93MAP3K10.62532025
94INSRR0.58021130
95STK380.57743552
96ERBB20.54966559
97EIF2AK10.52237398
98PRKCI0.49648408
99MAPKAPK20.49091637
100CHUK0.48945335
101MYLK0.47901010
102NTRK10.47440319
103GRK10.45134059
104BMX0.44407046
105CDK120.44003504
106PIM10.43787743
107BRAF0.43608000
108DDR20.41534951
109WNK40.39058469
110PRKAA20.38876044
111CAMK1D0.38081336
112NUAK10.37736714
113ABL20.36002743
114RAF10.35213857
115TAF10.34964400
116MAP3K130.34639442
117ICK0.34289612
118MUSK0.33575504
119CDK70.33417130
120MAP2K60.32358137
121DMPK0.32140038
122MAP2K30.31780712
123FGFR30.31132750
124PLK40.30767345
125MAP3K110.30757290
126ZAP700.30717557
127RPS6KB10.29222917
128SCYL20.29106826
129PASK0.29051582
130TEC0.27443862
131TBK10.27293277
132MTOR0.26695278
133CSNK1G10.24236508
134IRAK10.22929960
135EIF2AK20.22458401
136ROCK10.22163520
137IGF1R0.21676563
138JAK10.20992437
139CSNK1A10.20197529
140SGK4940.19693099
141SGK2230.19693099
142BRD40.19009265

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002324.15986454
2Fat digestion and absorption_Homo sapiens_hsa049753.16254601
3Steroid hormone biosynthesis_Homo sapiens_hsa001402.63437051
4Retinol metabolism_Homo sapiens_hsa008302.58827287
5Protein digestion and absorption_Homo sapiens_hsa049742.17662210
6Phenylalanine metabolism_Homo sapiens_hsa003602.15147412
7Bladder cancer_Homo sapiens_hsa052192.11688420
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.04474733
9Vitamin digestion and absorption_Homo sapiens_hsa049771.94708238
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.93597021
11Drug metabolism - other enzymes_Homo sapiens_hsa009831.90707904
12Sulfur metabolism_Homo sapiens_hsa009201.90547701
13Folate biosynthesis_Homo sapiens_hsa007901.86222394
14ECM-receptor interaction_Homo sapiens_hsa045121.83991278
15Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.75343115
16Mineral absorption_Homo sapiens_hsa049781.69384685
17Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.66795393
18Renin-angiotensin system_Homo sapiens_hsa046141.62720779
19Small cell lung cancer_Homo sapiens_hsa052221.53196065
20Tyrosine metabolism_Homo sapiens_hsa003501.51849458
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.51199917
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.50826497
23Fatty acid degradation_Homo sapiens_hsa000711.40529708
24Glutathione metabolism_Homo sapiens_hsa004801.39397870
25Pancreatic secretion_Homo sapiens_hsa049721.38672841
26Chemical carcinogenesis_Homo sapiens_hsa052041.37539801
27Thyroid cancer_Homo sapiens_hsa052161.33995141
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29528904
29Glycerolipid metabolism_Homo sapiens_hsa005611.29213212
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.28302935
31Ovarian steroidogenesis_Homo sapiens_hsa049131.27960665
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27009887
33Sphingolipid metabolism_Homo sapiens_hsa006001.25773845
34Cell cycle_Homo sapiens_hsa041101.20274983
35Arginine and proline metabolism_Homo sapiens_hsa003301.19996147
36Linoleic acid metabolism_Homo sapiens_hsa005911.19571250
37Pancreatic cancer_Homo sapiens_hsa052121.19404724
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.18994144
39p53 signaling pathway_Homo sapiens_hsa041151.18591257
40Arachidonic acid metabolism_Homo sapiens_hsa005901.17261239
41Nitrogen metabolism_Homo sapiens_hsa009101.15190926
42TGF-beta signaling pathway_Homo sapiens_hsa043501.14721195
43beta-Alanine metabolism_Homo sapiens_hsa004101.13442200
44Vitamin B6 metabolism_Homo sapiens_hsa007501.13429992
45Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.12399924
46Other glycan degradation_Homo sapiens_hsa005111.06681251
47Histidine metabolism_Homo sapiens_hsa003401.06366745
48PPAR signaling pathway_Homo sapiens_hsa033201.06151339
49Adherens junction_Homo sapiens_hsa045201.05814437
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01691204
51MicroRNAs in cancer_Homo sapiens_hsa052061.00844018
52Focal adhesion_Homo sapiens_hsa045100.98423293
53Galactose metabolism_Homo sapiens_hsa000520.98053437
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.95703292
55Butanoate metabolism_Homo sapiens_hsa006500.92850488
56Fatty acid biosynthesis_Homo sapiens_hsa000610.92484967
57Chronic myeloid leukemia_Homo sapiens_hsa052200.91589931
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.91267861
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90990499
60Fructose and mannose metabolism_Homo sapiens_hsa000510.90656981
61Starch and sucrose metabolism_Homo sapiens_hsa005000.90434469
62Toxoplasmosis_Homo sapiens_hsa051450.89720731
63ABC transporters_Homo sapiens_hsa020100.89556089
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88240979
65Amoebiasis_Homo sapiens_hsa051460.87856520
66Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.87266443
67Proteoglycans in cancer_Homo sapiens_hsa052050.86704717
68Platelet activation_Homo sapiens_hsa046110.86332298
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84004723
70Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.82084621
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81822384
72Leukocyte transendothelial migration_Homo sapiens_hsa046700.74048580
73Cysteine and methionine metabolism_Homo sapiens_hsa002700.72767885
74Ether lipid metabolism_Homo sapiens_hsa005650.71681818
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71350096
76Shigellosis_Homo sapiens_hsa051310.70844767
77Ribosome_Homo sapiens_hsa030100.69429407
78Hippo signaling pathway_Homo sapiens_hsa043900.68635433
79Tight junction_Homo sapiens_hsa045300.68583714
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68031084
81Sulfur relay system_Homo sapiens_hsa041220.65073071
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64515747
83Peroxisome_Homo sapiens_hsa041460.62906180
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62896215
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62075789
86Prolactin signaling pathway_Homo sapiens_hsa049170.60925021
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60540394
88Influenza A_Homo sapiens_hsa051640.58362008
89Insulin resistance_Homo sapiens_hsa049310.58012937
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.56232917
91Malaria_Homo sapiens_hsa051440.55246095
92Bile secretion_Homo sapiens_hsa049760.54853543
93Fatty acid metabolism_Homo sapiens_hsa012120.54397695
94Tryptophan metabolism_Homo sapiens_hsa003800.54217284
95Propanoate metabolism_Homo sapiens_hsa006400.53205503
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52781237
97Circadian rhythm_Homo sapiens_hsa047100.52523935
98Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52302785
99Pyruvate metabolism_Homo sapiens_hsa006200.52208993
100Selenocompound metabolism_Homo sapiens_hsa004500.52171913
101Hematopoietic cell lineage_Homo sapiens_hsa046400.51916514
102Basal transcription factors_Homo sapiens_hsa030220.51873342
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50709741
104TNF signaling pathway_Homo sapiens_hsa046680.50150456
105Steroid biosynthesis_Homo sapiens_hsa001000.49987664
106Acute myeloid leukemia_Homo sapiens_hsa052210.49089067
107Hepatitis C_Homo sapiens_hsa051600.48455142
108Melanoma_Homo sapiens_hsa052180.47929860
109VEGF signaling pathway_Homo sapiens_hsa043700.47856531
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47752853
111Leishmaniasis_Homo sapiens_hsa051400.47599566
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.47329893
113N-Glycan biosynthesis_Homo sapiens_hsa005100.46555055
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46176209
115Hepatitis B_Homo sapiens_hsa051610.44945117
116Glucagon signaling pathway_Homo sapiens_hsa049220.44412849
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43897534
118Thyroid hormone synthesis_Homo sapiens_hsa049180.43755044
119Apoptosis_Homo sapiens_hsa042100.43516488
120RNA degradation_Homo sapiens_hsa030180.42869719
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.42826019
122Arginine biosynthesis_Homo sapiens_hsa002200.42678917
123Complement and coagulation cascades_Homo sapiens_hsa046100.42108757
124Pathways in cancer_Homo sapiens_hsa052000.41211719
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40462267
126Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.37167887
127AMPK signaling pathway_Homo sapiens_hsa041520.36610161
128Metabolic pathways_Homo sapiens_hsa011000.35192585
129Dorso-ventral axis formation_Homo sapiens_hsa043200.33395860
130Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.27651857
131Renin secretion_Homo sapiens_hsa049240.25600904
132Choline metabolism in cancer_Homo sapiens_hsa052310.25089822
133Insulin signaling pathway_Homo sapiens_hsa049100.23251023
134Serotonergic synapse_Homo sapiens_hsa047260.19687565
135ErbB signaling pathway_Homo sapiens_hsa040120.19334985
136Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19292378
137Central carbon metabolism in cancer_Homo sapiens_hsa052300.17704861

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