FAM114A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the FAM114 family and may play a role in neuronal cell development. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)6.42399242
2COPI coating of Golgi vesicle (GO:0048205)6.42399242
3collagen fibril organization (GO:0030199)5.78570319
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.58202498
5protein retention in ER lumen (GO:0006621)5.23449456
6protein heterotrimerization (GO:0070208)4.99566586
7COPII vesicle coating (GO:0048208)4.61904837
8chondrocyte proliferation (GO:0035988)4.40343958
9peptidyl-proline hydroxylation (GO:0019511)4.03782417
10regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.00198381
11endodermal cell differentiation (GO:0035987)3.98671377
12skin morphogenesis (GO:0043589)3.91906485
13keratan sulfate catabolic process (GO:0042340)3.90946286
14collagen metabolic process (GO:0032963)3.84819425
15sequestering of extracellular ligand from receptor (GO:0035581)3.81466868
16regulation of integrin-mediated signaling pathway (GO:2001044)3.78861185
17collagen catabolic process (GO:0030574)3.76263746
184-hydroxyproline metabolic process (GO:0019471)3.69877718
19peptidyl-glutamic acid carboxylation (GO:0017187)3.69698050
20protein carboxylation (GO:0018214)3.69698050
21activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.68783831
22multicellular organismal macromolecule metabolic process (GO:0044259)3.62519652
23multicellular organismal catabolic process (GO:0044243)3.60498607
24regulation of metalloenzyme activity (GO:0048552)3.59960357
25multicellular organismal metabolic process (GO:0044236)3.56764655
26retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.56064366
27bone trabecula formation (GO:0060346)3.54307560
28positive regulation of nuclease activity (GO:0032075)3.46425442
29protein hydroxylation (GO:0018126)3.44581674
30chondrocyte development (GO:0002063)3.42041073
31negative regulation of fibrinolysis (GO:0051918)3.40332445
32apoptotic cell clearance (GO:0043277)3.40165935
33cell migration involved in heart development (GO:0060973)3.39560069
34cellular response to vitamin (GO:0071295)3.38251405
35cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.37583203
36cell adhesion mediated by integrin (GO:0033627)3.37279967
37endocardial cushion development (GO:0003197)3.35221740
38endoplasmic reticulum unfolded protein response (GO:0030968)3.32942362
39extracellular matrix disassembly (GO:0022617)3.31153406
40positive regulation of endothelial cell apoptotic process (GO:2000353)3.28640895
41cellular response to vitamin D (GO:0071305)3.28135758
42regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.27687922
43kidney mesenchyme development (GO:0072074)3.25790018
44cellular response to unfolded protein (GO:0034620)3.22591903
45regulation of plasminogen activation (GO:0010755)3.21327009
46exocrine pancreas development (GO:0031017)3.16995664
47positive regulation of extracellular matrix organization (GO:1903055)3.14865366
48negative regulation of axon extension involved in axon guidance (GO:0048843)3.14856366
49vesicle coating (GO:0006901)3.13106686
50regulation of nuclease activity (GO:0032069)3.08282783
51ER-nucleus signaling pathway (GO:0006984)3.06881962
52epoxygenase P450 pathway (GO:0019373)3.06589619
53substrate-dependent cell migration (GO:0006929)3.06244773
54extracellular regulation of signal transduction (GO:1900115)3.05356826
55extracellular negative regulation of signal transduction (GO:1900116)3.05356826
56substrate adhesion-dependent cell spreading (GO:0034446)3.04018873
57regulation of fibrinolysis (GO:0051917)3.03715551
58negative regulation of fatty acid transport (GO:2000192)3.02115515
59retina vasculature morphogenesis in camera-type eye (GO:0061299)2.99361120
60cellular response to topologically incorrect protein (GO:0035967)2.98716073
61basement membrane organization (GO:0071711)2.98239258
62regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.97870715
63smooth muscle tissue development (GO:0048745)2.95265621
64positive regulation of actin filament depolymerization (GO:0030836)2.95175229
65vascular endothelial growth factor signaling pathway (GO:0038084)2.94874582
66endothelial cell morphogenesis (GO:0001886)2.88019868
67mesenchymal-epithelial cell signaling (GO:0060638)2.86578151
68positive regulation of fatty acid beta-oxidation (GO:0032000)2.84609360
69blood vessel maturation (GO:0001955)2.80030671
70extracellular fibril organization (GO:0043206)2.78780441
71negative regulation of protein activation cascade (GO:2000258)2.77907530
72UDP-N-acetylglucosamine metabolic process (GO:0006047)2.74472739
73wound healing, spreading of epidermal cells (GO:0035313)2.74218995
74membrane raft organization (GO:0031579)2.73259221
75dermatan sulfate biosynthetic process (GO:0030208)2.72960197
76fibril organization (GO:0097435)2.72809058
77glomerular basement membrane development (GO:0032836)2.70569103
78regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.69770763
79intestinal cholesterol absorption (GO:0030299)2.69582048
80response to endoplasmic reticulum stress (GO:0034976)2.69212357
81actin filament depolymerization (GO:0030042)2.69185324
82neuron projection extension involved in neuron projection guidance (GO:1902284)2.67590614
83axon extension involved in axon guidance (GO:0048846)2.67590614
84extracellular matrix organization (GO:0030198)2.67192868
85extracellular structure organization (GO:0043062)2.65867674
86negative regulation of complement activation (GO:0045916)2.65422197
87mesodermal cell differentiation (GO:0048333)2.64916757
88insulin-like growth factor receptor signaling pathway (GO:0048009)2.64866918
89sequestering of metal ion (GO:0051238)2.64670268
90hemidesmosome assembly (GO:0031581)2.64235147
91fibrinolysis (GO:0042730)2.61885000
92lung vasculature development (GO:0060426)2.61092968
93response to unfolded protein (GO:0006986)2.60720980
94lymphangiogenesis (GO:0001946)2.59529508
95positive regulation of fatty acid oxidation (GO:0046321)2.59169812
96regulation of type B pancreatic cell apoptotic process (GO:2000674)2.58785826
97tooth mineralization (GO:0034505)2.58657559
98peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.57488185
99low-density lipoprotein particle clearance (GO:0034383)2.56904216
100negative regulation of chondrocyte differentiation (GO:0032331)2.56057158
101pericardium development (GO:0060039)2.55227478
102regulation of protein activation cascade (GO:2000257)2.54798799
103protein localization to cell surface (GO:0034394)2.53135937
104extracellular matrix assembly (GO:0085029)2.52735522
105response to redox state (GO:0051775)2.52725877
106regulation of complement activation (GO:0030449)2.52450964
107muscle cell migration (GO:0014812)2.52065280
108negative regulation of cartilage development (GO:0061037)2.51096352
109positive regulation of fibroblast migration (GO:0010763)2.50701295
110regulation of tight junction assembly (GO:2000810)2.49718894
111positive regulation of glycogen biosynthetic process (GO:0045725)2.49004403
112regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.48962543
113positive regulation of epithelial to mesenchymal transition (GO:0010718)2.46889086
114glomerular visceral epithelial cell development (GO:0072015)2.46770443
115response to topologically incorrect protein (GO:0035966)2.46562812
116regulation of glucose import in response to insulin stimulus (GO:2001273)2.45747586
117regulation of chondrocyte differentiation (GO:0032330)2.44303487
118dermatan sulfate metabolic process (GO:0030205)2.44302216
119sprouting angiogenesis (GO:0002040)2.44269667
120positive regulation of protein autophosphorylation (GO:0031954)2.43741856
121regulation of endothelial cell apoptotic process (GO:2000351)2.43254064
122negative regulation of axon guidance (GO:1902668)2.42933756
123regulation of extracellular matrix disassembly (GO:0010715)2.42753327
124desmosome organization (GO:0002934)2.42471752
125negative regulation of smooth muscle cell migration (GO:0014912)2.42366111
126signal peptide processing (GO:0006465)2.42230379
127endothelial cell proliferation (GO:0001935)2.41761074
128type B pancreatic cell proliferation (GO:0044342)2.41668977
129regulation of transforming growth factor beta1 production (GO:0032908)2.41037521
130negative regulation of lipase activity (GO:0060192)2.40255356
131fibroblast migration (GO:0010761)2.39298151
132embryonic cranial skeleton morphogenesis (GO:0048701)2.38255643
133nucleotide-sugar biosynthetic process (GO:0009226)2.37667327
134negative regulation of endothelial cell apoptotic process (GO:2000352)2.37075760
135barbed-end actin filament capping (GO:0051016)2.36907265
136homocysteine metabolic process (GO:0050667)2.36776212
137erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.36413050
138L-phenylalanine catabolic process (GO:0006559)2.36413050
139cellular response to nutrient (GO:0031670)2.36262284
140alpha-linolenic acid metabolic process (GO:0036109)2.35661679
141erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.35026065
142L-phenylalanine metabolic process (GO:0006558)2.35026065
143metanephric mesenchyme development (GO:0072075)2.34732934
144toxin metabolic process (GO:0009404)2.34284352
145opsonization (GO:0008228)2.34039799

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.38660230
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.66452985
3RARG_19884340_ChIP-ChIP_MEFs_Mouse4.54447046
4TP63_17297297_ChIP-ChIP_HaCaT_Human4.18706437
5CLOCK_20551151_ChIP-Seq_293T_Human3.57494049
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.54539516
7RXR_22158963_ChIP-Seq_LIVER_Mouse3.50654929
8LXR_22158963_ChIP-Seq_LIVER_Mouse3.06022658
9PPARA_22158963_ChIP-Seq_LIVER_Mouse2.91729743
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.89703452
11TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.86671700
12CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.69576178
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.53682330
14CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.48582327
15CJUN_26792858_Chip-Seq_BT549_Human2.44630227
16RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.42347564
17ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.39658179
18NRF2_20460467_ChIP-Seq_MEFs_Mouse2.34743937
19NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.34743937
20WT1_19549856_ChIP-ChIP_CCG9911_Human2.33929924
21TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.33150818
22ESR1_21235772_ChIP-Seq_MCF-7_Human2.24701981
23NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.13364335
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.05959210
25TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.03134970
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.00356785
27BRD4_25478319_ChIP-Seq_HGPS_Human1.93696939
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.85325511
29SOX2_20726797_ChIP-Seq_SW620_Human1.81394698
30SALL4_18804426_ChIP-ChIP_XEN_Mouse1.78903808
31EP300_21415370_ChIP-Seq_HL-1_Mouse1.77424164
32EGR1_23403033_ChIP-Seq_LIVER_Mouse1.70602174
33PPAR_26484153_Chip-Seq_NCI-H1993_Human1.68345365
34FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.68264447
35SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.61209065
36ESR2_21235772_ChIP-Seq_MCF-7_Human1.56513288
37HIF1A_21447827_ChIP-Seq_MCF-7_Human1.56274947
38ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.56200843
39CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.53251422
40GATA2_21666600_ChIP-Seq_HMVEC_Human1.52633577
41GBX2_23144817_ChIP-Seq_PC3_Human1.44772025
42SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.43926919
43SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.43926919
44JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.40635446
45* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.39791046
46SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.36400928
47JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.35469729
48RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.34378775
49CDX2_19796622_ChIP-Seq_MESCs_Mouse1.34121269
50ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33404668
51TBX20_22080862_ChIP-Seq_HEART_Mouse1.32895824
52TBX20_22328084_ChIP-Seq_HEART_Mouse1.32895824
53GATA1_22025678_ChIP-Seq_K562_Human1.32603670
54BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.31042016
55ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.23888816
56SOX2_27498859_Chip-Seq_STOMACH_Mouse1.22573163
57FOXM1_26456572_ChIP-Seq_MCF-7_Human1.21921139
58AHR_22903824_ChIP-Seq_MCF-7_Human1.21788014
59FOXO3_23340844_ChIP-Seq_DLD1_Human1.21717458
60ZNF217_24962896_ChIP-Seq_MCF-7_Human1.20967680
61CDX2_20551321_ChIP-Seq_CACO-2_Human1.19918779
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18115876
63NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.17907591
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.17355388
65SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16848687
66* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.14245596
67TP53_18474530_ChIP-ChIP_U2OS_Human1.14131558
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11821585
69GATA4_25053715_ChIP-Seq_YYC3_Human1.11778515
70UBF1/2_26484160_Chip-Seq_HMECs_Human1.11742398
71* FOXA2_19822575_ChIP-Seq_HepG2_Human1.10558518
72CDX2_22108803_ChIP-Seq_LS180_Human1.09941638
73NFIB_24661679_ChIP-Seq_LUNG_Mouse1.09261434
74MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.08764588
75Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07908227
76EGR1_19374776_ChIP-ChIP_THP-1_Human1.07780126
77P300_27058665_Chip-Seq_ZR-75-30cells_Human1.07301408
78ELK3_25401928_ChIP-Seq_HUVEC_Human1.06955249
79ATF3_27146783_Chip-Seq_COLON_Human1.06506391
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06022259
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.04576013
82SMAD4_21799915_ChIP-Seq_A2780_Human1.04438758
83KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04306925
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.04216903
85EOMES_21245162_ChIP-Seq_HESCs_Human1.04007321
86SMC1_22415368_ChIP-Seq_MEFs_Mouse1.03951752
87PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.03706945
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02804741
89WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02711664
90GATA3_24758297_ChIP-Seq_MCF-7_Human0.98366311
91PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97948097
92FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.96462591
93ESR1_20079471_ChIP-ChIP_T-47D_Human0.96198878
94FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.96116569
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.95252343
96P63_26484246_Chip-Seq_KERATINOCYTES_Human0.95209142
97TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94805038
98AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.93657997
99NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93437301
100POU3F2_20337985_ChIP-ChIP_501MEL_Human0.93384795
101CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92783734
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.92536760
103NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91986801
104ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.91659961
105PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.91477263
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.91415523
107BCAT_22108803_ChIP-Seq_LS180_Human0.89668860
108ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88402945
109EZH2_27294783_Chip-Seq_NPCs_Mouse0.88337881
110TP63_23658742_ChIP-Seq_EP156T_Human0.88241666
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.88103668
112HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86847079
113SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.86447941
114TP53_16413492_ChIP-PET_HCT116_Human0.86359129
115SMAD3_21741376_ChIP-Seq_HESCs_Human0.86090465
116TCF4_18268006_ChIP-ChIP_LS174T_Human0.85092839
117EED_16625203_ChIP-ChIP_MESCs_Mouse0.84420430
118PCGF2_27294783_Chip-Seq_NPCs_Mouse0.83480952
119P300_19829295_ChIP-Seq_ESCs_Human0.83384681
120SUZ12_27294783_Chip-Seq_NPCs_Mouse0.82569573
121SA1_22415368_ChIP-Seq_MEFs_Mouse0.82559316
122FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.82421175
123RBPJ_22232070_ChIP-Seq_NCS_Mouse0.81951742
124TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.81307676
125RACK7_27058665_Chip-Seq_MCF-7_Human0.81074936
126PIAS1_25552417_ChIP-Seq_VCAP_Human0.80323593
127KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.79697193
128TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.78364772
129ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77025491
130* TP53_23651856_ChIP-Seq_MEFs_Mouse0.76880475
131TP53_20018659_ChIP-ChIP_R1E_Mouse0.76281133
132IRF8_22096565_ChIP-ChIP_GC-B_Human0.75889991

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen7.62901775
2MP0005503_abnormal_tendon_morphology4.98669335
3MP0005275_abnormal_skin_tensile4.78606143
4MP0003705_abnormal_hypodermis_morpholog3.90976184
5MP0003950_abnormal_plasma_membrane3.84797242
6MP0003279_aneurysm3.15273565
7MP0009384_cardiac_valve_regurgitation2.89541454
8MP0004272_abnormal_basement_membrane2.73153260
9MP0006054_spinal_hemorrhage2.71490339
10MP0001958_emphysema2.53399727
11MP0002139_abnormal_hepatobiliary_system2.20249892
12MP0002060_abnormal_skin_morphology1.95424990
13MP0005508_abnormal_skeleton_morphology1.93192361
14MP0002877_abnormal_melanocyte_morpholog1.92839189
15MP0000013_abnormal_adipose_tissue1.83741254
16MP0002896_abnormal_bone_mineralization1.80582823
17MP0003252_abnormal_bile_duct1.78415552
18MP0003283_abnormal_digestive_organ1.75639759
19MP0005623_abnormal_meninges_morphology1.75293400
20MP0005257_abnormal_intraocular_pressure1.74267849
21MP0002295_abnormal_pulmonary_circulatio1.70184862
22MP0003566_abnormal_cell_adhesion1.70046787
23MP0010368_abnormal_lymphatic_system1.69827690
24MP0005023_abnormal_wound_healing1.69009516
25MP0001542_abnormal_bone_strength1.68099147
26MP0005365_abnormal_bile_salt1.66519402
27MP0003941_abnormal_skin_development1.64271468
28MP0003191_abnormal_cellular_cholesterol1.55084119
29MP0005220_abnormal_exocrine_pancreas1.52228584
30MP0002108_abnormal_muscle_morphology1.51595785
31MP0009780_abnormal_chondrocyte_physiolo1.51433817
32MP0005360_urolithiasis1.44040116
33MP0000163_abnormal_cartilage_morphology1.37025561
34MP0005085_abnormal_gallbladder_physiolo1.36930072
35MP0009250_abnormal_appendicular_skeleto1.34335409
36MP0001243_abnormal_dermal_layer1.34169016
37MP0002933_joint_inflammation1.28657420
38MP0005390_skeleton_phenotype1.28166077
39MP0002115_abnormal_skeleton_extremities1.27452415
40MP0003195_calcinosis1.24239551
41MP0010352_gastrointestinal_tract_polyps1.22385361
42MP0003091_abnormal_cell_migration1.22299628
43MP0002168_other_aberrant_phenotype1.15809700
44MP0001299_abnormal_eye_distance/1.15233499
45MP0000751_myopathy1.14391061
46MP0004134_abnormal_chest_morphology1.11856025
47MP0000762_abnormal_tongue_morphology1.11666357
48MP0000767_abnormal_smooth_muscle1.11206497
49MP0000749_muscle_degeneration1.09293357
50MP0002254_reproductive_system_inflammat1.08883154
51MP0001666_abnormal_nutrient_absorption1.07860632
52MP0001533_abnormal_skeleton_physiology1.06528500
53MP0008004_abnormal_stomach_pH1.06392166
54MP0005083_abnormal_biliary_tract1.05927692
55MP0003385_abnormal_body_wall1.05335983
56MP0003868_abnormal_feces_composition1.04483569
57MP0010030_abnormal_orbit_morphology1.04361083
58MP0000003_abnormal_adipose_tissue1.03816594
59MP0002282_abnormal_trachea_morphology1.03107434
60MP0003045_fibrosis1.02973584
61MP0002837_dystrophic_cardiac_calcinosis1.02384197
62MP0001879_abnormal_lymphatic_vessel1.01751945
63MP0005165_increased_susceptibility_to1.01342183
64MP0009053_abnormal_anal_canal0.99766049
65MP0003806_abnormal_nucleotide_metabolis0.99549622
66MP0003942_abnormal_urinary_system0.98517688
67MP0003795_abnormal_bone_structure0.97927063
68MP0002928_abnormal_bile_duct0.97914209
69MP0003300_gastrointestinal_ulcer0.96081463
70MP0002113_abnormal_skeleton_development0.95710911
71MP0005084_abnormal_gallbladder_morpholo0.93100649
72MP0002998_abnormal_bone_remodeling0.92542688
73MP0001944_abnormal_pancreas_morphology0.90558433
74MP0005197_abnormal_uvea_morphology0.89432323
75MP0002876_abnormal_thyroid_physiology0.89031432
76MP0005171_absent_coat_pigmentation0.83761989
77MP0010329_abnormal_lipoprotein_level0.79802941
78MP0004883_abnormal_blood_vessel0.78803159
79MP0010386_abnormal_urinary_bladder0.78483277
80MP0000733_abnormal_muscle_development0.75066789
81MP0005670_abnormal_white_adipose0.74913024
82MP0005164_abnormal_response_to0.74654737
83MP0003115_abnormal_respiratory_system0.73896316
84MP0002109_abnormal_limb_morphology0.73718345
85MP0000428_abnormal_craniofacial_morphol0.73672874
86MP0000534_abnormal_ureter_morphology0.72837728
87MP0005595_abnormal_vascular_smooth0.71910492
88MP0002128_abnormal_blood_circulation0.70631249
89MP0002932_abnormal_joint_morphology0.70239312
90MP0001270_distended_abdomen0.69744635
91MP0008775_abnormal_heart_ventricle0.69291701
92MP0005375_adipose_tissue_phenotype0.69164395
93MP0003186_abnormal_redox_activity0.67763385
94MP0000750_abnormal_muscle_regeneration0.67214570
95MP0001661_extended_life_span0.67059337
96MP0001756_abnormal_urination0.66295187
97MP0000432_abnormal_head_morphology0.65046508
98MP0005193_abnormal_anterior_eye0.64482263
99MP0005076_abnormal_cell_differentiation0.64050287
100MP0000639_abnormal_adrenal_gland0.63730728
101MP0005058_abnormal_lysosome_morphology0.63510950
102MP0005367_renal/urinary_system_phenotyp0.62039330
103MP0000516_abnormal_urinary_system0.62039330
104MP0005395_other_phenotype0.61066419
105MP0003755_abnormal_palate_morphology0.60931283
106MP0005330_cardiomyopathy0.60495621
107MP0002089_abnormal_postnatal_growth/wei0.58033885
108MP0000613_abnormal_salivary_gland0.57367342
109MP0000462_abnormal_digestive_system0.56995148
110MP0005332_abnormal_amino_acid0.55187373
111MP0010234_abnormal_vibrissa_follicle0.55057797
112MP0001915_intracranial_hemorrhage0.54857901
113MP0000538_abnormal_urinary_bladder0.54492373
114MP0005620_abnormal_muscle_contractility0.52952908
115MP0009840_abnormal_foam_cell0.52767319
116MP0001614_abnormal_blood_vessel0.52635086
117MP0003935_abnormal_craniofacial_develop0.52480493
118MP0009643_abnormal_urine_homeostasis0.52288296
119MP0005666_abnormal_adipose_tissue0.52286108
120MP0005319_abnormal_enzyme/_coenzyme0.52145328
121MP0000609_abnormal_liver_physiology0.52126910
122MP0004084_abnormal_cardiac_muscle0.52048452
123MP0001175_abnormal_lung_morphology0.51785801
124MP0005408_hypopigmentation0.51337430
125MP0002118_abnormal_lipid_homeostasis0.50945932

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.72961389
2Premature rupture of membranes (HP:0001788)7.09049643
3Aortic dissection (HP:0002647)4.47837689
4Peritonitis (HP:0002586)4.21467571
5Soft skin (HP:0000977)4.15569871
6Ankle contracture (HP:0006466)4.09001368
7Abnormality of dentin (HP:0010299)4.02949346
8Cervical subluxation (HP:0003308)4.02890329
9Atrophic scars (HP:0001075)3.95878768
10Aortic aneurysm (HP:0004942)3.95670202
11Broad metatarsal (HP:0001783)3.63496198
12Shallow orbits (HP:0000586)3.53218046
13Neonatal short-limb short stature (HP:0008921)3.52057569
14Vertebral compression fractures (HP:0002953)3.51566043
15Dilatation of the ascending aorta (HP:0005111)3.42833854
16Cerebral aneurysm (HP:0004944)3.42433130
17Biconcave vertebral bodies (HP:0004586)3.41472864
18Bladder diverticulum (HP:0000015)3.38981977
19Wormian bones (HP:0002645)3.27588257
20Blue sclerae (HP:0000592)3.26467163
21Follicular hyperkeratosis (HP:0007502)3.24089601
22Fragile skin (HP:0001030)3.23119092
23Spinal rigidity (HP:0003306)3.09333300
24Mitral valve prolapse (HP:0001634)3.07225101
25Type 1 muscle fiber predominance (HP:0003803)2.96286334
26Genu recurvatum (HP:0002816)2.94520130
27Abnormal delivery (HP:0001787)2.90553514
28Abnormality of the acetabulum (HP:0003170)2.78319146
29Abnormality of the intrinsic pathway (HP:0010989)2.71244443
30Vascular calcification (HP:0004934)2.65618971
31Osteoarthritis (HP:0002758)2.64364413
32Ectopia lentis (HP:0001083)2.63610959
33Cupped ribs (HP:0000887)2.61277556
34Vascular tortuosity (HP:0004948)2.60540588
35Hyperextensible skin (HP:0000974)2.57779454
36Overgrowth (HP:0001548)2.56423084
37Aortic regurgitation (HP:0001659)2.52789352
38Nonimmune hydrops fetalis (HP:0001790)2.50468272
39Aneurysm (HP:0002617)2.48123993
40Beaking of vertebral bodies (HP:0004568)2.45928205
41Increased connective tissue (HP:0009025)2.44263259
42Platyspondyly (HP:0000926)2.41483768
43Delayed gross motor development (HP:0002194)2.39248372
44Abnormality of the common coagulation pathway (HP:0010990)2.37669198
45Wrist flexion contracture (HP:0001239)2.36869751
46Mildly elevated creatine phosphokinase (HP:0008180)2.36858776
47Infantile muscular hypotonia (HP:0008947)2.34081316
48Breech presentation (HP:0001623)2.33230508
49Coxa vara (HP:0002812)2.32775043
50Epiphyseal dysplasia (HP:0002656)2.31933476
51Hypoalphalipoproteinemia (HP:0003233)2.31387820
52Aortic valve stenosis (HP:0001650)2.31146496
53Deep venous thrombosis (HP:0002625)2.29772641
54Arterial tortuosity (HP:0005116)2.28222114
55Thin bony cortex (HP:0002753)2.26636808
56Mitral stenosis (HP:0001718)2.25670103
57Bowel diverticulosis (HP:0005222)2.25339467
58Spondylolisthesis (HP:0003302)2.24499764
59Hypoplastic ischia (HP:0003175)2.24373153
60Coronal craniosynostosis (HP:0004440)2.22415511
61Mesomelia (HP:0003027)2.19819817
62Thoracolumbar scoliosis (HP:0002944)2.19126369
63Hypoglycemic coma (HP:0001325)2.18227831
64Abnormality of the ischium (HP:0003174)2.16740253
65Increased variability in muscle fiber diameter (HP:0003557)2.16535062
66Short nail (HP:0001799)2.15439417
67Elbow flexion contracture (HP:0002987)2.15189562
68Joint stiffness (HP:0001387)2.15110464
69Abnormality of carpal bone ossification (HP:0006257)2.13542140
70Joint laxity (HP:0001388)2.12096557
71Hypolipoproteinemia (HP:0010981)2.11961054
72Wide anterior fontanel (HP:0000260)2.11701713
73Round ear (HP:0100830)2.07052715
74Ovoid vertebral bodies (HP:0003300)2.05893436
75Bell-shaped thorax (HP:0001591)2.05563885
76Osteolytic defects of the phalanges of the hand (HP:0009771)2.05464342
77Osteolytic defects of the hand bones (HP:0009699)2.05464342
78Tibial bowing (HP:0002982)2.05320575
79Abnormal tarsal ossification (HP:0008369)2.05011155
80Slender build (HP:0001533)2.03776058
81Femoral bowing (HP:0002980)2.02913626
82Delayed closure of the anterior fontanelle (HP:0001476)2.01627956
83Metaphyseal dysplasia (HP:0100255)1.99671202
84Abnormal foot bone ossification (HP:0010675)1.99560159
85Keratoconus (HP:0000563)1.99195590
86Increased corneal curvature (HP:0100692)1.99195590
87Camptodactyly of toe (HP:0001836)1.98617258
88Xanthomatosis (HP:0000991)1.96615497
89Back pain (HP:0003418)1.93971328
90Hydroxyprolinuria (HP:0003080)1.93722699
91Abnormality of proline metabolism (HP:0010907)1.93722699
92Natal tooth (HP:0000695)1.93287804
93Absent frontal sinuses (HP:0002688)1.92709543
94Protuberant abdomen (HP:0001538)1.90889241
95Hypoplasia of the iris (HP:0007676)1.88634213
96Skin nodule (HP:0200036)1.88235779
97Mitral regurgitation (HP:0001653)1.87508548
98Mild short stature (HP:0003502)1.85855823
99Intrahepatic cholestasis (HP:0001406)1.85612378
100Generalized amyotrophy (HP:0003700)1.85308448
101Osteopenia (HP:0000938)1.84209379
102Flared iliac wings (HP:0002869)1.83745959
103Abnormality of skeletal muscle fiber size (HP:0012084)1.82337995
104Inguinal hernia (HP:0000023)1.81441345
105Myocardial infarction (HP:0001658)1.81120297
106Broad long bones (HP:0005622)1.80991396
107Reduced subcutaneous adipose tissue (HP:0003758)1.80058553
108Abnormal cartilage morphology (HP:0002763)1.80007522
109Delayed cranial suture closure (HP:0000270)1.79873176
110Microglossia (HP:0000171)1.79827767
111Glucose intolerance (HP:0000833)1.78895732
112Abnormality of skull ossification (HP:0002703)1.78770042
113Hyperglycemia (HP:0003074)1.78165924
114Congenital glaucoma (HP:0001087)1.77902067
115Limited hip movement (HP:0008800)1.77708098
116Knee flexion contracture (HP:0006380)1.77046740
117Abnormality of glutamine family amino acid metabolism (HP:0010902)1.76755252
118Protruding ear (HP:0000411)1.76751826
119Broad ribs (HP:0000885)1.76221972
120Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.75939887
121Decreased skull ossification (HP:0004331)1.75918320
122Right ventricular cardiomyopathy (HP:0011663)1.73558945
123Hypoglycemic seizures (HP:0002173)1.72202747
124Flat acetabular roof (HP:0003180)1.72190026
125Hypoplasia of the odontoid process (HP:0003311)1.71740669
126Ulnar bowing (HP:0003031)1.71159159
127Striae distensae (HP:0001065)1.70929927
128Cardiovascular calcification (HP:0011915)1.70691070
129Hypobetalipoproteinemia (HP:0003563)1.69490209
130Abnormal hand bone ossification (HP:0010660)1.66709776
131Pectus carinatum (HP:0000768)1.66216865
132Bradycardia (HP:0001662)1.65956137
133Abnormal ossification of hand bones (HP:0005921)1.62447296
134Thin skin (HP:0000963)1.62370158
135Gingival overgrowth (HP:0000212)1.60639752
136Tetraparesis (HP:0002273)1.59839016

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.13642289
2ERN13.95188354
3FRK3.39109642
4TRIB33.38290154
5LATS13.03893110
6PDGFRA2.98369307
7SIK12.96658928
8MAP3K122.75460138
9TTN2.39821734
10PKN22.16483529
11AKT32.15146578
12PTK61.94873987
13LATS21.92883575
14EPHA31.91220348
15INSRR1.88297912
16MAP3K31.75942292
17PTK21.73307950
18FLT31.71314758
19LMTK21.71020277
20MAPK151.62528423
21TRPM71.62296370
22TGFBR21.61307195
23MUSK1.57857627
24BCKDK1.53873747
25FER1.51476315
26RIPK11.44809087
27TESK11.44396578
28PAK21.44011765
29MET1.43531757
30NEK91.42647772
31PIK3CG1.42598179
32EPHB21.35351173
33PIK3CA1.31172785
34PAK31.26621558
35FGFR41.23820364
36TIE11.23731048
37TAOK31.21697829
38GRK11.19595303
39NUAK11.17468490
40ERBB31.14851927
41STK381.14585968
42STK38L1.13298507
43MYLK1.10623770
44STK31.09566193
45PLK21.08956886
46PASK1.06720390
47ADRBK11.06296363
48MST41.05774662
49RPS6KA41.04372468
50STK391.03170054
51BMX1.00234287
52PDK20.99312889
53CDC42BPA0.97257078
54PDGFRB0.96713933
55MAP3K20.96501066
56LIMK10.93121356
57JAK10.92002158
58LRRK20.91700065
59ROCK20.91286255
60NTRK10.88295098
61CAMK1D0.86778676
62PRKG20.86673613
63PTK2B0.86616071
64PIM20.86115012
65FGFR10.85828988
66MAPKAPK30.85063284
67MAP2K10.83965464
68NEK10.83249020
69SCYL20.83248814
70ACVR1B0.82448087
71PBK0.82237411
72MTOR0.79954273
73EPHB10.79737666
74EIF2AK10.78404386
75CAMKK20.77073670
76IRAK30.76717920
77EEF2K0.74198697
78MOS0.72801931
79FGFR30.72207612
80ROCK10.72085132
81MST1R0.71617079
82MAP2K30.67521931
83PAK40.66740030
84ADRBK20.65494145
85DAPK30.64320953
86KDR0.62997203
87DMPK0.61795445
88PRKD30.61731748
89WNK40.61693803
90BCR0.61620865
91TGFBR10.60272794
92JAK30.59574148
93MELK0.59437834
94GRK70.58698031
95IRAK10.58612862
96EIF2AK30.58010466
97BRSK20.57982799
98PRKCH0.57735660
99ABL20.57171695
100ERBB40.54950326
101EPHA20.52918040
102CDK80.52361172
103RET0.52217507
104PRKD10.50912988
105IGF1R0.50544221
106TBK10.50537260
107NLK0.49166592
108DYRK1B0.48805793
109GRK50.48461630
110INSR0.47159780
111GSK3A0.46424789
112PAK60.45862503
113FGFR20.45805367
114CAMK2D0.45537132
115STK160.43482450
116NME20.43378879
117PHKG20.42871584
118PHKG10.42871584
119TRIM280.42537734
120ILK0.42509544
121MAP3K60.41424837
122CAMK1G0.41356247
123BMPR1B0.40752122
124PRKCE0.38593844
125CAMK2G0.38478432
126PRKD20.37998369
127HIPK20.37090115
128MAP2K20.35373443
129ABL10.35237959
130WNK10.35192978
131CHUK0.34798041
132CSK0.33745947
133MAP3K10.31657937
134MAPKAPK50.31334574
135PAK10.30918043
136CDK60.28933090
137ERBB20.28081592

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.21473255
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.07686473
3Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.63668915
4Protein digestion and absorption_Homo sapiens_hsa049742.60517596
5Sulfur metabolism_Homo sapiens_hsa009202.42613376
6Protein export_Homo sapiens_hsa030602.41725625
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.22912479
8Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.19819985
9Complement and coagulation cascades_Homo sapiens_hsa046102.07779197
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.06944621
11Focal adhesion_Homo sapiens_hsa045102.03891198
12Tryptophan metabolism_Homo sapiens_hsa003801.85183695
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.67332236
14Fatty acid degradation_Homo sapiens_hsa000711.64479822
15Starch and sucrose metabolism_Homo sapiens_hsa005001.54264327
16Amoebiasis_Homo sapiens_hsa051461.46799879
17Selenocompound metabolism_Homo sapiens_hsa004501.40256938
18Pentose and glucuronate interconversions_Homo sapiens_hsa000401.40137088
19Vitamin B6 metabolism_Homo sapiens_hsa007501.39728520
20Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.36744368
21PPAR signaling pathway_Homo sapiens_hsa033201.36740334
22Fat digestion and absorption_Homo sapiens_hsa049751.34356633
23Mineral absorption_Homo sapiens_hsa049781.31009052
24Bladder cancer_Homo sapiens_hsa052191.30156569
25Malaria_Homo sapiens_hsa051441.29781482
26Fatty acid elongation_Homo sapiens_hsa000621.28201030
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27415114
28Proteoglycans in cancer_Homo sapiens_hsa052051.27386319
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.27082638
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.24914410
31Caffeine metabolism_Homo sapiens_hsa002321.23714829
32Nitrogen metabolism_Homo sapiens_hsa009101.22843360
33N-Glycan biosynthesis_Homo sapiens_hsa005101.17008065
34Adherens junction_Homo sapiens_hsa045201.16516478
35Arginine biosynthesis_Homo sapiens_hsa002201.13410483
36Chemical carcinogenesis_Homo sapiens_hsa052041.09701430
37Regulation of actin cytoskeleton_Homo sapiens_hsa048101.08993196
38Sphingolipid metabolism_Homo sapiens_hsa006001.05041390
39AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.04600651
40PI3K-Akt signaling pathway_Homo sapiens_hsa041511.03007964
41Fatty acid metabolism_Homo sapiens_hsa012120.99845838
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.97299010
43Hedgehog signaling pathway_Homo sapiens_hsa043400.96946927
44Folate biosynthesis_Homo sapiens_hsa007900.96135200
45TGF-beta signaling pathway_Homo sapiens_hsa043500.96033029
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95993882
47Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.95220955
48Galactose metabolism_Homo sapiens_hsa000520.94753773
49Insulin resistance_Homo sapiens_hsa049310.92472457
50Lysosome_Homo sapiens_hsa041420.92445061
51Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.92124784
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91483403
53Propanoate metabolism_Homo sapiens_hsa006400.90572297
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90056302
55Small cell lung cancer_Homo sapiens_hsa052220.89779854
56Arginine and proline metabolism_Homo sapiens_hsa003300.89461771
57Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.89193791
58Peroxisome_Homo sapiens_hsa041460.87661341
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.87261942
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86783599
61Tight junction_Homo sapiens_hsa045300.86437166
62Butanoate metabolism_Homo sapiens_hsa006500.86017242
63Steroid hormone biosynthesis_Homo sapiens_hsa001400.85538546
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.84834660
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84494027
66Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.83230975
67Dilated cardiomyopathy_Homo sapiens_hsa054140.81934610
68Histidine metabolism_Homo sapiens_hsa003400.80994683
69Prion diseases_Homo sapiens_hsa050200.79918268
70Other glycan degradation_Homo sapiens_hsa005110.79489737
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77138212
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.77022378
73Staphylococcus aureus infection_Homo sapiens_hsa051500.75333225
74Phenylalanine metabolism_Homo sapiens_hsa003600.73594060
75Ovarian steroidogenesis_Homo sapiens_hsa049130.73476254
76Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.73341292
77Circadian rhythm_Homo sapiens_hsa047100.73262853
78Lysine degradation_Homo sapiens_hsa003100.73002982
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72466589
80Renin-angiotensin system_Homo sapiens_hsa046140.72392888
81Thyroid hormone synthesis_Homo sapiens_hsa049180.70262216
82Bile secretion_Homo sapiens_hsa049760.69845517
83Prostate cancer_Homo sapiens_hsa052150.66788376
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66541618
85Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66340268
86Fructose and mannose metabolism_Homo sapiens_hsa000510.66235334
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66149593
88Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65864267
89Drug metabolism - other enzymes_Homo sapiens_hsa009830.65862766
90Cyanoamino acid metabolism_Homo sapiens_hsa004600.65779114
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65657137
92Tyrosine metabolism_Homo sapiens_hsa003500.65629187
93Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.65516752
94Arachidonic acid metabolism_Homo sapiens_hsa005900.62985825
95Hippo signaling pathway_Homo sapiens_hsa043900.59417125
96Steroid biosynthesis_Homo sapiens_hsa001000.58997848
97Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57685743
98Vibrio cholerae infection_Homo sapiens_hsa051100.56730801
992-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.55227634
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.55217371
101Retinol metabolism_Homo sapiens_hsa008300.54933956
102Vitamin digestion and absorption_Homo sapiens_hsa049770.54736227
103MicroRNAs in cancer_Homo sapiens_hsa052060.54243423
104beta-Alanine metabolism_Homo sapiens_hsa004100.54075880
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53590663
106Phagosome_Homo sapiens_hsa041450.53143282
107TNF signaling pathway_Homo sapiens_hsa046680.52105019
108Melanoma_Homo sapiens_hsa052180.51614665
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49935995
110Pentose phosphate pathway_Homo sapiens_hsa000300.47173677
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46451267
112Pyruvate metabolism_Homo sapiens_hsa006200.46361712
113Toxoplasmosis_Homo sapiens_hsa051450.46287499
114Chronic myeloid leukemia_Homo sapiens_hsa052200.46247633
115Basal cell carcinoma_Homo sapiens_hsa052170.45948355
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.45598264
117One carbon pool by folate_Homo sapiens_hsa006700.43600553
118Glutathione metabolism_Homo sapiens_hsa004800.43402314
119ABC transporters_Homo sapiens_hsa020100.43142701
120Pathways in cancer_Homo sapiens_hsa052000.42853685
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.42170241
122Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39847155
123Metabolic pathways_Homo sapiens_hsa011000.39793726
124Prolactin signaling pathway_Homo sapiens_hsa049170.39068982
125Legionellosis_Homo sapiens_hsa051340.38267167
126Central carbon metabolism in cancer_Homo sapiens_hsa052300.38054549
127Pertussis_Homo sapiens_hsa051330.37380184
128Glucagon signaling pathway_Homo sapiens_hsa049220.37170657

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