FAM120A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)3.89778059
2COPI coating of Golgi vesicle (GO:0048205)3.89778059
3negative regulation of fatty acid transport (GO:2000192)3.75834132
4protein localization to endosome (GO:0036010)3.75598108
5hypotonic response (GO:0006971)3.71360697
6desmosome organization (GO:0002934)3.56473614
7maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.36794996
8negative regulation of erythrocyte differentiation (GO:0045647)3.30347062
9regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.28127983
10positive regulation of Cdc42 GTPase activity (GO:0043089)3.28062507
11glucocorticoid receptor signaling pathway (GO:0042921)3.24873825
12regulation of histone H3-K27 methylation (GO:0061085)3.24262869
13focal adhesion assembly (GO:0048041)3.23124773
14cell-substrate adherens junction assembly (GO:0007045)3.23124773
15antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.17162760
16antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.17162760
17nuclear pore complex assembly (GO:0051292)3.15812703
18regulation of glucose import in response to insulin stimulus (GO:2001273)3.11538162
19protein retention in ER lumen (GO:0006621)3.11255297
20response to laminar fluid shear stress (GO:0034616)3.08226305
21regulation of early endosome to late endosome transport (GO:2000641)3.07601997
22activation of Rac GTPase activity (GO:0032863)3.04432152
23regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.01183763
24adherens junction assembly (GO:0034333)2.98997130
25pinocytosis (GO:0006907)2.95943401
26positive regulation of keratinocyte differentiation (GO:0045618)2.93275585
27regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.92546046
28positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.91914916
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.87156930
30positive regulation of histone deacetylation (GO:0031065)2.86068845
31cell adhesion mediated by integrin (GO:0033627)2.85311607
32collagen fibril organization (GO:0030199)2.85019831
33nuclear pore organization (GO:0006999)2.84029152
34corticosteroid receptor signaling pathway (GO:0031958)2.82574723
35antigen processing and presentation of endogenous antigen (GO:0019883)2.80248349
36negative regulation of protein localization to plasma membrane (GO:1903077)2.77439988
37positive regulation of natural killer cell differentiation (GO:0032825)2.76594952
38growth hormone receptor signaling pathway (GO:0060396)2.76508979
39endodermal cell differentiation (GO:0035987)2.74443928
40COPII vesicle coating (GO:0048208)2.73346812
41insulin-like growth factor receptor signaling pathway (GO:0048009)2.70167426
42barbed-end actin filament capping (GO:0051016)2.69838171
43negative regulation of phagocytosis (GO:0050765)2.69246436
44apoptotic cell clearance (GO:0043277)2.68752707
45activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.67216561
46stress fiber assembly (GO:0043149)2.66166340
47epithelial cell differentiation involved in prostate gland development (GO:0060742)2.65290728
48positive regulation of protein import into nucleus, translocation (GO:0033160)2.64885058
49maternal placenta development (GO:0001893)2.64786416
50keratan sulfate catabolic process (GO:0042340)2.64630136
51membrane raft organization (GO:0031579)2.62563538
52embryonic process involved in female pregnancy (GO:0060136)2.62007666
53mammary gland epithelial cell proliferation (GO:0033598)2.60077246
54cytoskeletal anchoring at plasma membrane (GO:0007016)2.59634720
55definitive hemopoiesis (GO:0060216)2.59011168
56positive regulation of nuclease activity (GO:0032075)2.58754291
57pentose-phosphate shunt (GO:0006098)2.54804004
58endoplasmic reticulum unfolded protein response (GO:0030968)2.52869330
59epithelial cell-cell adhesion (GO:0090136)2.50267445
60branching involved in mammary gland duct morphogenesis (GO:0060444)2.49346811
61cytoplasmic mRNA processing body assembly (GO:0033962)2.49175535
62positive regulation of p38MAPK cascade (GO:1900745)2.48967826
63negative regulation of anoikis (GO:2000811)2.45775159
64positive regulation of receptor recycling (GO:0001921)2.45360459
65regulation of extracellular matrix disassembly (GO:0010715)2.44561274
66cellular response to unfolded protein (GO:0034620)2.44424875
67regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.42121515
68ER-nucleus signaling pathway (GO:0006984)2.40957405
69regulation of translational termination (GO:0006449)2.40468090
70iron ion import (GO:0097286)2.39986849
71pore complex assembly (GO:0046931)2.39701869
72cellular response to growth hormone stimulus (GO:0071378)2.38570645
73regulation of nuclease activity (GO:0032069)2.37978653
74membrane protein ectodomain proteolysis (GO:0006509)2.37772575
75regulation of cholesterol storage (GO:0010885)2.36780615
76hormone catabolic process (GO:0042447)2.35494617
77cellular response to epidermal growth factor stimulus (GO:0071364)2.34704312
78fibroblast migration (GO:0010761)2.33445464
79mitotic chromosome condensation (GO:0007076)2.33101713
80negative regulation of viral release from host cell (GO:1902187)2.32675757
81response to peptidoglycan (GO:0032494)2.31663627
82endothelial cell morphogenesis (GO:0001886)2.31455767
83hemidesmosome assembly (GO:0031581)2.31022854
84apoptotic process involved in morphogenesis (GO:0060561)2.30635586
85regulation of apoptotic cell clearance (GO:2000425)2.27615386
86regulation of nucleobase-containing compound transport (GO:0032239)2.27357789
87antigen processing and presentation via MHC class Ib (GO:0002475)2.27222930
88valine metabolic process (GO:0006573)2.25775592
89regulation of cholesterol homeostasis (GO:2000188)2.25472036
90regulation of anoikis (GO:2000209)2.24785368
91embryonic eye morphogenesis (GO:0048048)2.24552314
92positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.24326758
93positive regulation of extracellular matrix organization (GO:1903055)2.23703999
94basement membrane organization (GO:0071711)2.23689971
95positive regulation of epidermal cell differentiation (GO:0045606)2.23477330
96protein heterotrimerization (GO:0070208)2.23228525
97JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.22630378
98regulation of protein localization to plasma membrane (GO:1903076)2.22250058
99peptide catabolic process (GO:0043171)2.22063071
100positive regulation of DNA-templated transcription, initiation (GO:2000144)2.21268312
101regulation of transforming growth factor beta1 production (GO:0032908)2.21184828
102Arp2/3 complex-mediated actin nucleation (GO:0034314)2.20819836
103positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.20651040
104establishment of endothelial barrier (GO:0061028)2.19488374
105skin morphogenesis (GO:0043589)2.19477917
1063-UTR-mediated mRNA stabilization (GO:0070935)2.18806565
107UDP-N-acetylglucosamine metabolic process (GO:0006047)2.17477815
108mRNA transcription (GO:0009299)2.17390479
109positive regulation of endothelial cell apoptotic process (GO:2000353)2.17254555
110glucose catabolic process (GO:0006007)2.16687248
111regulation of integrin activation (GO:0033623)2.16621218
112positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.15724967
113hepatocyte apoptotic process (GO:0097284)2.15525148
114cell-substrate junction assembly (GO:0007044)2.15378524
115regulation of protein import into nucleus, translocation (GO:0033158)2.15265447
116cellular response to topologically incorrect protein (GO:0035967)2.15214503
117regulation of RNA export from nucleus (GO:0046831)2.15004016
118surfactant homeostasis (GO:0043129)2.14878784
119low-density lipoprotein particle clearance (GO:0034383)2.14552803
120mannose metabolic process (GO:0006013)2.14551579
121vesicle coating (GO:0006901)2.14507985
122trophectodermal cell differentiation (GO:0001829)2.13994053
123regulation of necroptotic process (GO:0060544)2.12735142
124positive regulation of blood vessel endothelial cell migration (GO:0043536)2.12530582
125negative regulation of establishment of protein localization to plasma membrane (GO:0090005)2.12341891
126lysine catabolic process (GO:0006554)2.12057061
127lysine metabolic process (GO:0006553)2.12057061
128wound healing, spreading of epidermal cells (GO:0035313)2.12041355
129regulation of interleukin-12 biosynthetic process (GO:0045075)2.12005512
130retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.11998866
131negative regulation of lipid transport (GO:0032369)2.11844686
132negative regulation of necroptotic process (GO:0060546)2.11471661
133regulation of fatty acid beta-oxidation (GO:0031998)2.11031762
134response to epidermal growth factor (GO:0070849)2.10882492
135cortical actin cytoskeleton organization (GO:0030866)2.10600561
136IMP biosynthetic process (GO:0006188)2.10091946
137mRNA stabilization (GO:0048255)2.09368707
138RNA stabilization (GO:0043489)2.09368707
139mitotic sister chromatid cohesion (GO:0007064)2.09291927
140negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.09134052
141substrate adhesion-dependent cell spreading (GO:0034446)2.09120393
142bundle of His cell to Purkinje myocyte communication (GO:0086069)2.08519746
143NADPH regeneration (GO:0006740)2.08470228
144cellular response to vitamin D (GO:0071305)2.07829927
145positive regulation of gamma-delta T cell activation (GO:0046645)2.07287268
146regulation of type I interferon-mediated signaling pathway (GO:0060338)2.06153149
147negative regulation of cell size (GO:0045792)2.05959881
148vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.05716777
149phospholipid homeostasis (GO:0055091)2.05452773
150positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.05057748
151collagen metabolic process (GO:0032963)2.04434545
152regulation of keratinocyte differentiation (GO:0045616)2.04227114
153embryonic camera-type eye morphogenesis (GO:0048596)2.03704327
154NLS-bearing protein import into nucleus (GO:0006607)2.03421347
155organ regeneration (GO:0031100)2.02762784
156IMP metabolic process (GO:0046040)2.02602591
157glycoprotein catabolic process (GO:0006516)2.01975479
158hippo signaling (GO:0035329)2.01559855
159cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.01348640
160angiogenesis involved in wound healing (GO:0060055)2.00993351
161response to interferon-alpha (GO:0035455)2.00675414
162positive regulation of protein deacetylation (GO:0090312)2.00251948

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.28493629
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.16144713
3TP63_17297297_ChIP-ChIP_HaCaT_Human3.92621220
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.77967314
5IRF8_22096565_ChIP-ChIP_GC-B_Human2.95349035
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.79495970
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.79317001
8CLOCK_20551151_ChIP-Seq_293T_Human2.52642045
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.42840528
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.42560538
11ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.37015334
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.34329981
13GATA1_22025678_ChIP-Seq_K562_Human2.18115147
14ZNF263_19887448_ChIP-Seq_K562_Human2.15989820
15MYC_22102868_ChIP-Seq_BL_Human2.14276602
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.06062745
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.00931116
18NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.92646876
19PPARA_22158963_ChIP-Seq_LIVER_Mouse1.91612249
20RXR_22158963_ChIP-Seq_LIVER_Mouse1.88164445
21KDM2B_26808549_Chip-Seq_SUP-B15_Human1.85190774
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.83024452
23SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.80268211
24KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.77318965
25* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.73863577
26LXR_22158963_ChIP-Seq_LIVER_Mouse1.72731596
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.72500055
28LXR_22292898_ChIP-Seq_THP-1_Human1.70960893
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.70734225
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.70706795
31RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.69786241
32PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.69282775
33TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67824913
34TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.67706733
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.66869077
36SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.65353173
37SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.65353173
38Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.62995399
39STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.62822633
40MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.61614959
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.59929830
42THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.59717396
43STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59604908
44RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.56277207
45AR_21909140_ChIP-Seq_LNCAP_Human1.56184849
46TCF7_22412390_ChIP-Seq_EML_Mouse1.52609734
47ESR1_21235772_ChIP-Seq_MCF-7_Human1.52368559
48TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.52352483
49HIF1A_21447827_ChIP-Seq_MCF-7_Human1.48917966
50BRD4_25478319_ChIP-Seq_HGPS_Human1.47530903
51* IRF8_27001747_Chip-Seq_BMDM_Mouse1.45263502
52STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.44661750
53NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.43770575
54FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.43683575
55NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.43034892
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40552203
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.39733301
58GATA2_21666600_ChIP-Seq_HMVEC_Human1.37890724
59MYB_26560356_Chip-Seq_TH2_Human1.36448952
60PPAR_26484153_Chip-Seq_NCI-H1993_Human1.36040437
61RUNX1_27514584_Chip-Seq_MCF-7_Human1.34787300
62MYB_26560356_Chip-Seq_TH1_Human1.33235535
63TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.32975332
64FOXO3_23340844_ChIP-Seq_DLD1_Human1.32336446
65SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.31679848
66* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.31172940
67FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.30167363
68MAF_26560356_Chip-Seq_TH1_Human1.29283537
69EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.28255160
70KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28007573
71NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.25216793
72SOX9_24532713_ChIP-Seq_HFSC_Mouse1.25030594
73DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24336416
74ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.24004462
75GATA6_25053715_ChIP-Seq_YYC3_Human1.22830841
76KLF4_18555785_ChIP-Seq_MESCs_Mouse1.21832047
77VDR_24763502_ChIP-Seq_THP-1_Human1.20857214
78CJUN_26792858_Chip-Seq_BT549_Human1.20441687
79WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.20376887
80ATF3_27146783_Chip-Seq_COLON_Human1.20090287
81IRF8_21731497_ChIP-ChIP_J774_Mouse1.19804696
82VDR_21846776_ChIP-Seq_THP-1_Human1.19457520
83CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.19424861
84P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17883199
85E2F1_21310950_ChIP-Seq_MCF-7_Human1.17732320
86RUNX_20019798_ChIP-Seq_JUKART_Human1.17395613
87* PU_27001747_Chip-Seq_BMDM_Mouse1.16988050
88KDM2B_26808549_Chip-Seq_JURKAT_Human1.16543990
89KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.16259674
90UBF1/2_26484160_Chip-Seq_HMECs_Human1.16085642
91KDM2B_26808549_Chip-Seq_K562_Human1.16052017
92* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.15893062
93TBX20_22080862_ChIP-Seq_HEART_Mouse1.15832194
94TBX20_22328084_ChIP-Seq_HEART_Mouse1.15832194
95STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15572954
96SALL4_18804426_ChIP-ChIP_XEN_Mouse1.15433595
97SCL_19346495_ChIP-Seq_HPC-7_Human1.15294773
98GATA1_22383799_ChIP-Seq_G1ME_Mouse1.14488651
99* SPI1_23127762_ChIP-Seq_K562_Human1.08849030
100GATA4_25053715_ChIP-Seq_YYC3_Human1.08644296
101ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.08585482
102FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.08270046
103TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.08041569
104* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.08032135
105BP1_19119308_ChIP-ChIP_Hs578T_Human1.07643616
106ESR2_21235772_ChIP-Seq_MCF-7_Human1.07578021
107KDM2B_26808549_Chip-Seq_DND41_Human1.07059106
108ESR1_20079471_ChIP-ChIP_T-47D_Human1.06768519
109* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.06767537
110IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.05341282
111CHD1_26751641_Chip-Seq_LNCaP_Human1.05235306
112NCOR1_26117541_ChIP-Seq_K562_Human1.04847558
113SOX2_20726797_ChIP-Seq_SW620_Human1.04324082
114RACK7_27058665_Chip-Seq_MCF-7_Human1.03094395
115STAT4_19710469_ChIP-ChIP_TH1__Mouse1.02954117
116KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02296558
117* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02243330
118HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.02189784
119UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.01857592
120P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01407356
121UTX_26944678_Chip-Seq_JUKART_Human1.00373031
122CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99804527
123ZFX_18555785_ChIP-Seq_MESCs_Mouse0.99615154
124* RUNX1_22412390_ChIP-Seq_EML_Mouse0.99275534
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.98429534
126CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98143584
127TFEB_21752829_ChIP-Seq_HELA_Human0.96734002
128JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96023023
129RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95097397
130TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94790814
131FOXA2_19822575_ChIP-Seq_HepG2_Human0.94099331

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.85242622
2MP0008438_abnormal_cutaneous_collagen3.43957793
3MP0002877_abnormal_melanocyte_morpholog3.26292165
4MP0006054_spinal_hemorrhage2.80938085
5MP0010352_gastrointestinal_tract_polyps2.73284121
6MP0003300_gastrointestinal_ulcer2.72228210
7MP0005451_abnormal_body_composition2.50994980
8MP0003566_abnormal_cell_adhesion2.27959980
9MP0005275_abnormal_skin_tensile2.21929268
10MP0005503_abnormal_tendon_morphology2.11425540
11MP0002796_impaired_skin_barrier1.89497723
12MP0005409_darkened_coat_color1.86397578
13MP0004185_abnormal_adipocyte_glucose1.86265839
14MP0010234_abnormal_vibrissa_follicle1.82303868
15MP0005076_abnormal_cell_differentiation1.75049112
16MP0003279_aneurysm1.74462228
17MP0002166_altered_tumor_susceptibility1.65793328
18MP0010307_abnormal_tumor_latency1.61007564
19MP0004808_abnormal_hematopoietic_stem1.59858033
20MP0003252_abnormal_bile_duct1.59412655
21MP0004272_abnormal_basement_membrane1.58754927
22MP0004233_abnormal_muscle_weight1.56476007
23MP0005023_abnormal_wound_healing1.55318504
24MP0002060_abnormal_skin_morphology1.50000375
25MP0000569_abnormal_digit_pigmentation1.47890770
26MP0003763_abnormal_thymus_physiology1.40266626
27MP0002396_abnormal_hematopoietic_system1.38928013
28MP0004264_abnormal_extraembryonic_tissu1.34759839
29MP0002139_abnormal_hepatobiliary_system1.34628487
30MP0005501_abnormal_skin_physiology1.28940924
31MP0003828_pulmonary_edema1.28099154
32MP0001958_emphysema1.26529547
33MP0001849_ear_inflammation1.26407642
34MP0002006_tumorigenesis1.26032871
35MP0008260_abnormal_autophagy1.24943790
36MP0005666_abnormal_adipose_tissue1.23716929
37MP0000733_abnormal_muscle_development1.21911463
38MP0005360_urolithiasis1.21189222
39MP0001216_abnormal_epidermal_layer1.18117525
40MP0004858_abnormal_nervous_system1.16828014
41MP0003436_decreased_susceptibility_to1.16642678
42MP0009053_abnormal_anal_canal1.14656442
43MP0003091_abnormal_cell_migration1.13757889
44MP0010368_abnormal_lymphatic_system1.12449806
45MP0002138_abnormal_hepatobiliary_system1.11733622
46MP0000516_abnormal_urinary_system1.11532680
47MP0005367_renal/urinary_system_phenotyp1.11532680
48MP0005397_hematopoietic_system_phenotyp1.10701233
49MP0001545_abnormal_hematopoietic_system1.10701233
50MP0004947_skin_inflammation1.07943522
51MP0004782_abnormal_surfactant_physiolog1.06845180
52MP0001243_abnormal_dermal_layer1.05219770
53MP0003045_fibrosis1.04960567
54MP0001915_intracranial_hemorrhage1.04947929
55MP0003303_peritoneal_inflammation1.02293079
56MP0000767_abnormal_smooth_muscle1.02104148
57MP0005375_adipose_tissue_phenotype1.01238631
58MP0005621_abnormal_cell_physiology1.00692119
59MP0000678_abnormal_parathyroid_gland0.99612462
60MP0003191_abnormal_cellular_cholesterol0.99417132
61MP0010155_abnormal_intestine_physiology0.98908932
62MP0009384_cardiac_valve_regurgitation0.98860950
63MP0003183_abnormal_peptide_metabolism0.98329837
64MP0009278_abnormal_bone_marrow0.97572042
65MP0002896_abnormal_bone_mineralization0.96834025
66MP0001348_abnormal_lacrimal_gland0.96686233
67MP0000858_altered_metastatic_potential0.96127646
68MP0005257_abnormal_intraocular_pressure0.94876080
69MP0009333_abnormal_splenocyte_physiolog0.94531511
70MP0000371_diluted_coat_color0.94406972
71MP0002933_joint_inflammation0.93729087
72MP0005408_hypopigmentation0.93382462
73MP0001835_abnormal_antigen_presentation0.93344549
74MP0003943_abnormal_hepatobiliary_system0.93197935
75MP0001879_abnormal_lymphatic_vessel0.93194476
76MP0004197_abnormal_fetal_growth/weight/0.92566276
77MP0001851_eye_inflammation0.92563217
78MP0003453_abnormal_keratinocyte_physiol0.91985179
79MP0010678_abnormal_skin_adnexa0.90639312
80MP0001533_abnormal_skeleton_physiology0.90567677
81MP0000685_abnormal_immune_system0.90561579
82MP0000490_abnormal_crypts_of0.90394703
83MP0005365_abnormal_bile_salt0.88992827
84MP0000003_abnormal_adipose_tissue0.88975415
85MP0003448_altered_tumor_morphology0.87478154
86MP0005508_abnormal_skeleton_morphology0.87406043
87MP0001730_embryonic_growth_arrest0.86674851
88MP0002998_abnormal_bone_remodeling0.86586185
89MP0002086_abnormal_extraembryonic_tissu0.85822928
90MP0003172_abnormal_lysosome_physiology0.84568828
91MP0003950_abnormal_plasma_membrane0.84282550
92MP0005248_abnormal_Harderian_gland0.84220070
93MP0009931_abnormal_skin_appearance0.83139538
94MP0005464_abnormal_platelet_physiology0.83137764
95MP0003795_abnormal_bone_structure0.80891309
96MP0010329_abnormal_lipoprotein_level0.79723001
97MP0005164_abnormal_response_to0.79695710
98MP0005390_skeleton_phenotype0.79037581
99MP0000377_abnormal_hair_follicle0.78759429
100MP0002115_abnormal_skeleton_extremities0.77859153
101MP0003868_abnormal_feces_composition0.77789346
102MP0008057_abnormal_DNA_replication0.77673551
103MP0004087_abnormal_muscle_fiber0.77614131
104MP0003656_abnormal_erythrocyte_physiolo0.77510406
105MP0001881_abnormal_mammary_gland0.76618957
106MP0000598_abnormal_liver_morphology0.76395708
107MP0003984_embryonic_growth_retardation0.75857328
108MP0002928_abnormal_bile_duct0.75798792
109MP0004381_abnormal_hair_follicle0.75709949
110MP0002088_abnormal_embryonic_growth/wei0.75537842
111MP0002128_abnormal_blood_circulation0.75296682
112MP0000350_abnormal_cell_proliferation0.75290534
113MP0009780_abnormal_chondrocyte_physiolo0.75005529
114MP0005085_abnormal_gallbladder_physiolo0.74996943
115MP0001661_extended_life_span0.74921380
116MP0002098_abnormal_vibrissa_morphology0.74672415
117MP0002168_other_aberrant_phenotype0.74221561
118MP0000609_abnormal_liver_physiology0.73741362
119MP0006138_congestive_heart_failure0.73656720
120MP0000751_myopathy0.73592447
121MP0003567_abnormal_fetal_cardiomyocyte0.72960081
122MP0005623_abnormal_meninges_morphology0.72943422
123MP0009840_abnormal_foam_cell0.72701666
124MP0000747_muscle_weakness0.72443558
125MP0002925_abnormal_cardiovascular_devel0.71893969
126MP0000759_abnormal_skeletal_muscle0.71668044
127MP0002113_abnormal_skeleton_development0.71491804
128MP0003866_abnormal_defecation0.71361410
129MP0010630_abnormal_cardiac_muscle0.71265800
130MP0005220_abnormal_exocrine_pancreas0.70613632
131MP0005165_increased_susceptibility_to0.70544664
132MP0001790_abnormal_immune_system0.70372508
133MP0005387_immune_system_phenotype0.70372508
134MP0003941_abnormal_skin_development0.70014991
135MP0008007_abnormal_cellular_replicative0.69551337
136MP0001853_heart_inflammation0.69548578
137MP0005025_abnormal_response_to0.69499344
138MP0003115_abnormal_respiratory_system0.68976980
139MP0005058_abnormal_lysosome_morphology0.68544769
140MP0002419_abnormal_innate_immunity0.67979606
141MP0000627_abnormal_mammary_gland0.67785940
142MP0002405_respiratory_system_inflammati0.67488585
143MP0000163_abnormal_cartilage_morphology0.67416618
144MP0002009_preneoplasia0.67271605
145MP0001873_stomach_inflammation0.66451295
146MP0002089_abnormal_postnatal_growth/wei0.65930645

Predicted human phenotypes

RankGene SetZ-score
1Cervical subluxation (HP:0003308)3.62550590
2Protrusio acetabuli (HP:0003179)3.49145600
3Subacute progressive viral hepatitis (HP:0006572)3.03930731
4Premature rupture of membranes (HP:0001788)3.00446045
5Aortic aneurysm (HP:0004942)2.88747288
6Spinal cord lesions (HP:0100561)2.88602208
7Syringomyelia (HP:0003396)2.88602208
8Cerebral aneurysm (HP:0004944)2.80429878
9Asymmetry of the thorax (HP:0001555)2.77334509
10Osteolytic defects of the hand bones (HP:0009699)2.75007230
11Osteolytic defects of the phalanges of the hand (HP:0009771)2.75007230
12Abnormal foot bone ossification (HP:0010675)2.67274557
13Flat acetabular roof (HP:0003180)2.61395431
14Cupped ribs (HP:0000887)2.59310982
15Hyperacusis (HP:0010780)2.58602588
16Distal lower limb muscle weakness (HP:0009053)2.53679563
17Distal lower limb amyotrophy (HP:0008944)2.52097600
18Epiphyseal dysplasia (HP:0002656)2.50634201
19Ankle contracture (HP:0006466)2.49482554
20Ankyloglossia (HP:0010296)2.48720508
21Autoimmune thrombocytopenia (HP:0001973)2.44610771
22Absent frontal sinuses (HP:0002688)2.41615756
23Aortic dissection (HP:0002647)2.40759982
24Arterial tortuosity (HP:0005116)2.40594362
25Increased connective tissue (HP:0009025)2.40469654
26Hypoplastic ischia (HP:0003175)2.38019628
27Mitral valve prolapse (HP:0001634)2.32885184
28Increased mean platelet volume (HP:0011877)2.32808053
29Myocardial infarction (HP:0001658)2.32604993
30Dilatation of the ascending aorta (HP:0005111)2.32300307
31Hematochezia (HP:0002573)2.30425110
32Abnormality of oral frenula (HP:0000190)2.30249374
33Abnormality of the ischium (HP:0003174)2.27142941
34Right ventricular cardiomyopathy (HP:0011663)2.26155998
35Centrally nucleated skeletal muscle fibers (HP:0003687)2.25618812
36Abnormal platelet volume (HP:0011876)2.25008092
37Abnormality of the fingertips (HP:0001211)2.22025462
38Atrophic scars (HP:0001075)2.21160082
39Thin bony cortex (HP:0002753)2.21067014
40Cutaneous melanoma (HP:0012056)2.18372475
41Enlarged penis (HP:0000040)2.15881221
42Aneurysm (HP:0002617)2.14436928
43Increased variability in muscle fiber diameter (HP:0003557)2.11602566
44Abnormality of skeletal muscle fiber size (HP:0012084)2.09552834
45Rectal prolapse (HP:0002035)2.08240616
46Shallow orbits (HP:0000586)2.07190753
47Macroorchidism (HP:0000053)2.03962529
48Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.01233721
49Achilles tendon contracture (HP:0001771)2.00936658
50Exostoses (HP:0100777)2.00114615
51Metaphyseal cupping (HP:0003021)1.97185176
52Nonimmune hydrops fetalis (HP:0001790)1.96245905
53Cellulitis (HP:0100658)1.94270025
54Abnormality of the acetabulum (HP:0003170)1.94066917
55Micronodular cirrhosis (HP:0001413)1.93972111
56Vertebral compression fractures (HP:0002953)1.93059603
57Advanced eruption of teeth (HP:0006288)1.91291600
58Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.89904456
59Short 4th metacarpal (HP:0010044)1.89904456
60Abnormal tarsal ossification (HP:0008369)1.87787485
61Neoplasm of the adrenal cortex (HP:0100641)1.87592253
62Abnormality of the distal phalanx of the thumb (HP:0009617)1.87323001
63Wormian bones (HP:0002645)1.87298472
64Blue sclerae (HP:0000592)1.86374378
65Abnormality of the Achilles tendon (HP:0005109)1.85371275
66Short nail (HP:0001799)1.85194996
67Hemorrhage of the eye (HP:0011885)1.83904372
68Radial bowing (HP:0002986)1.83552219
69Periodontitis (HP:0000704)1.83316859
70Mesomelia (HP:0003027)1.82589178
71Upper limb amyotrophy (HP:0009129)1.82422080
72Distal upper limb amyotrophy (HP:0007149)1.82422080
73Ulnar bowing (HP:0003031)1.82085155
74Spinal cord compression (HP:0002176)1.81986945
75Peritonitis (HP:0002586)1.80906359
76Esophageal varix (HP:0002040)1.80806077
77Spondylolisthesis (HP:0003302)1.80382859
78Lymphangioma (HP:0100764)1.79876070
79Thoracolumbar scoliosis (HP:0002944)1.79796545
80Obstructive sleep apnea (HP:0002870)1.79426976
81Abnormality of the distal phalanges of the toes (HP:0010182)1.78982522
82Increased density of long bones (HP:0006392)1.78196559
83Dysmetric saccades (HP:0000641)1.77974428
84Back pain (HP:0003418)1.77203140
85Abnormality of the intrinsic pathway (HP:0010989)1.76577988
86Sparse lateral eyebrow (HP:0005338)1.76073074
87Disproportionate tall stature (HP:0001519)1.75986355
88Bilateral sensorineural hearing impairment (HP:0008619)1.75783383
89Interstitial pulmonary disease (HP:0006530)1.75462508
90Neonatal short-limb short stature (HP:0008921)1.75307817
91Platyspondyly (HP:0000926)1.74227630
92Broad metatarsal (HP:0001783)1.73185701
93Deep venous thrombosis (HP:0002625)1.71376475
94Hepatocellular carcinoma (HP:0001402)1.71344733
95Polycythemia (HP:0001901)1.71071048
96Severe short stature (HP:0003510)1.71051139
97Colitis (HP:0002583)1.70516369
98Gingivitis (HP:0000230)1.70476217
99Deep philtrum (HP:0002002)1.69758389
100Eczematoid dermatitis (HP:0000976)1.69689703
101Fatigue (HP:0012378)1.69671445
102Natal tooth (HP:0000695)1.69180768
103Exercise-induced myalgia (HP:0003738)1.68803061
104Vascular tortuosity (HP:0004948)1.68219206
105Elbow flexion contracture (HP:0002987)1.68134735
106Hyperparathyroidism (HP:0000843)1.67802497
107Abnormal ossification of hand bones (HP:0005921)1.67734166
108Vitreoretinal degeneration (HP:0000655)1.67065058
109Hyperglycemia (HP:0003074)1.66948854
110Mitral regurgitation (HP:0001653)1.66479635
111Trismus (HP:0000211)1.66243230
112Abnormality of the common coagulation pathway (HP:0010990)1.66088028
113Urethral obstruction (HP:0000796)1.65468135
114Abnormality of the frontal sinuses (HP:0002687)1.64304728
115Viral hepatitis (HP:0006562)1.63797449
116Mildly elevated creatine phosphokinase (HP:0008180)1.63473091
117Abnormality of monocarboxylic acid metabolism (HP:0010996)1.63320844
118Insidious onset (HP:0003587)1.63258625
119Termporal pattern (HP:0011008)1.63258625
120Asymmetric septal hypertrophy (HP:0001670)1.62792196
121Abnormality of the thoracic spine (HP:0100711)1.62491360
122Abnormality of carpal bone ossification (HP:0006257)1.62058578
123Fragile skin (HP:0001030)1.61656069
124Hydroxyprolinuria (HP:0003080)1.61477158
125Abnormality of proline metabolism (HP:0010907)1.61477158
126Mitral stenosis (HP:0001718)1.61276767
127Spinal rigidity (HP:0003306)1.61154231
128Bone pain (HP:0002653)1.60709157
129Abnormality of the calcaneus (HP:0008364)1.60546202
130Abdominal distention (HP:0003270)1.60230492
131Type 1 muscle fiber predominance (HP:0003803)1.59591177
132Malnutrition (HP:0004395)1.57817099
133Coarse hair (HP:0002208)1.57481307
134Genu recurvatum (HP:0002816)1.57082448
135Glucose intolerance (HP:0000833)1.57004889
136Ovoid vertebral bodies (HP:0003300)1.56892847
137Stillbirth (HP:0003826)1.56662150
138Tibial bowing (HP:0002982)1.56511360
139Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.56480042
140Dislocated radial head (HP:0003083)1.56196220
141Persistence of primary teeth (HP:0006335)1.56111285
142Beaking of vertebral bodies (HP:0004568)1.55984122
143Long palpebral fissure (HP:0000637)1.55950970
144Milia (HP:0001056)1.55461696
145Bladder diverticulum (HP:0000015)1.55344465
146J-shaped sella turcica (HP:0002680)1.55243791
147Broad face (HP:0000283)1.54463902
148Ectopia lentis (HP:0001083)1.54135491
149Hepatoblastoma (HP:0002884)1.54103719
150Vertebral hypoplasia (HP:0008417)1.53889781
151Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.53889781
152Gastrointestinal inflammation (HP:0004386)1.53400270
153Abnormal vertebral ossification (HP:0100569)1.52651270
154Coxa vara (HP:0002812)1.51613865
155Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.51564612

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.67806456
2PKN23.31125793
3FRK3.18849203
4PRPF4B3.17966223
5SMG13.02993166
6LATS12.30343462
7TTN2.27854235
8ICK2.11407043
9SIK12.09548499
10NEK92.03478639
11MAP3K142.02960290
12ERN12.02769538
13CDK121.97224856
14PTK61.91386109
15EEF2K1.89996572
16MAP3K101.79113681
17TRPM71.74223644
18RIPK11.69784483
19FGFR31.62991086
20STK31.57416815
21JAK31.51236708
22STK101.48525024
23MAP3K131.46563426
24RIPK41.45365797
25MST1R1.40787817
26JAK11.38521685
27PDGFRA1.38033837
28SCYL21.36682120
29KSR21.36668247
30CDK61.35836040
31LRRK21.34545087
32ERBB31.33676758
33BMX1.31777409
34DDR21.29156605
35MAP3K31.25385719
36TGFBR21.25275845
37RPS6KA41.21711177
38CHUK1.21039606
39EPHA31.20468848
40MAP4K11.20274453
41PRKG21.19816650
42CAMK1D1.18214925
43FGFR41.18061397
44TAOK31.16182224
45STK241.12800957
46ZAK1.11728668
47SGK31.10158165
48SIK31.08821162
49LMTK21.07887877
50TESK11.07432074
51NUAK11.07040494
52FLT31.05985737
53EPHA21.05364788
54NME21.04244401
55PIM11.02077334
56MAP2K31.01364798
57MTOR0.95165997
58MAP3K60.94049646
59MAP3K10.92636010
60LATS20.90353956
61TYK20.89699477
62CDC42BPA0.89466564
63PDPK10.88077483
64TBK10.87567277
65PRKCH0.87008358
66MARK30.86888947
67TAOK20.85535560
68PIM20.82644200
69MELK0.81240433
70STK40.78755946
71PRKD20.78173984
72BRSK20.77486025
73SGK20.76025682
74MAPK110.75767816
75PAK20.75142441
76CDK40.71377094
77ZAP700.71161152
78ALK0.69409864
79MAP3K80.68165640
80IRAK20.65711616
81DMPK0.65233482
82PDGFRB0.64208739
83TGFBR10.63712317
84INSRR0.63705816
85PASK0.63491735
86PTK20.62655247
87TAOK10.62647188
88NEK20.61788370
89PAK40.61714853
90EIF2AK10.60775518
91JAK20.60772180
92EPHB10.60375047
93STK380.59520733
94CAMK1G0.57379611
95IRAK30.56744876
96NEK10.55219149
97FER0.55086599
98HIPK20.54687607
99BMPR20.54532813
100CDK70.53618469
101IKBKE0.53158056
102STK38L0.52314440
103PDK10.52063029
104RPS6KB10.51348997
105FGFR10.50802763
106MYLK0.49235481
107MARK20.49230188
108CSF1R0.48629919
109MAP3K70.48319392
110MOS0.47777665
111RAF10.46470478
112PRKD30.46221657
113MAPKAPK30.45686953
114CSK0.44610351
115MST40.44256476
116RPS6KB20.44180478
117ARAF0.43799452
118MAPKAPK20.43488899
119IRAK40.43038219
120RPS6KL10.42909362
121RPS6KC10.42909362
122BTK0.42550018
123YES10.42231269
124BLK0.39684888
125KIT0.38405706
126ITK0.38186274
127WNK10.38078961
128MAP2K20.37644863
129RET0.37198130
130MAP3K50.37048990
131MAP3K20.36699279
132ILK0.36455894
133FGFR20.36401352
134NEK60.36292559
135MET0.36027012
136RPS6KA20.36015168
137IKBKB0.35751397
138TEC0.35748420
139MAPK70.35524870

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052201.82573609
2ECM-receptor interaction_Homo sapiens_hsa045121.76824228
3Renal cell carcinoma_Homo sapiens_hsa052111.69102570
4Adherens junction_Homo sapiens_hsa045201.69045677
5Small cell lung cancer_Homo sapiens_hsa052221.66711928
6Focal adhesion_Homo sapiens_hsa045101.65329950
7Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.63346549
8Other glycan degradation_Homo sapiens_hsa005111.60807869
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.59091254
10Proteoglycans in cancer_Homo sapiens_hsa052051.55238399
11Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.46738930
12Lysine degradation_Homo sapiens_hsa003101.42902264
13Leishmaniasis_Homo sapiens_hsa051401.42782216
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.40465909
15VEGF signaling pathway_Homo sapiens_hsa043701.39179372
16Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.37689935
17Nitrogen metabolism_Homo sapiens_hsa009101.35268781
18Caffeine metabolism_Homo sapiens_hsa002321.31345217
19Pentose phosphate pathway_Homo sapiens_hsa000301.30385019
20Thyroid cancer_Homo sapiens_hsa052161.29834807
21Viral myocarditis_Homo sapiens_hsa054161.28336137
22Toxoplasmosis_Homo sapiens_hsa051451.28187180
23AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.27614682
24Insulin resistance_Homo sapiens_hsa049311.25145754
25Endometrial cancer_Homo sapiens_hsa052131.24077017
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24056402
27Antigen processing and presentation_Homo sapiens_hsa046121.23877620
28MicroRNAs in cancer_Homo sapiens_hsa052061.23361934
29Acute myeloid leukemia_Homo sapiens_hsa052211.20859897
30Legionellosis_Homo sapiens_hsa051341.20515424
31Amoebiasis_Homo sapiens_hsa051461.18568329
32Starch and sucrose metabolism_Homo sapiens_hsa005001.18473358
33Leukocyte transendothelial migration_Homo sapiens_hsa046701.17870231
34Prostate cancer_Homo sapiens_hsa052151.14863921
35Protein digestion and absorption_Homo sapiens_hsa049741.14747003
36Selenocompound metabolism_Homo sapiens_hsa004501.13252923
37Insulin signaling pathway_Homo sapiens_hsa049101.12563016
38NF-kappa B signaling pathway_Homo sapiens_hsa040641.12505502
39Measles_Homo sapiens_hsa051621.11638242
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.11466097
41Osteoclast differentiation_Homo sapiens_hsa043801.11300069
42Prion diseases_Homo sapiens_hsa050201.09878069
43Pancreatic cancer_Homo sapiens_hsa052121.09000645
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.08862812
45One carbon pool by folate_Homo sapiens_hsa006701.08597713
46Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.07450544
47Hepatitis B_Homo sapiens_hsa051611.04959663
48Notch signaling pathway_Homo sapiens_hsa043301.04384340
49Bladder cancer_Homo sapiens_hsa052191.03505412
50ErbB signaling pathway_Homo sapiens_hsa040121.02761634
51TNF signaling pathway_Homo sapiens_hsa046681.02476599
52Fructose and mannose metabolism_Homo sapiens_hsa000511.02368844
53Glycosaminoglycan degradation_Homo sapiens_hsa005311.00656153
54Apoptosis_Homo sapiens_hsa042100.99895789
55Pentose and glucuronate interconversions_Homo sapiens_hsa000400.98362487
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97830060
57Viral carcinogenesis_Homo sapiens_hsa052030.95363078
58Non-small cell lung cancer_Homo sapiens_hsa052230.94817757
59Toll-like receptor signaling pathway_Homo sapiens_hsa046200.94115998
60Galactose metabolism_Homo sapiens_hsa000520.93947711
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.93849777
62Prolactin signaling pathway_Homo sapiens_hsa049170.93445673
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92213000
64Staphylococcus aureus infection_Homo sapiens_hsa051500.92040924
65HTLV-I infection_Homo sapiens_hsa051660.91852248
66Complement and coagulation cascades_Homo sapiens_hsa046100.91581667
67Choline metabolism in cancer_Homo sapiens_hsa052310.91282330
68Platelet activation_Homo sapiens_hsa046110.91221197
69T cell receptor signaling pathway_Homo sapiens_hsa046600.91028723
70Inositol phosphate metabolism_Homo sapiens_hsa005620.90858631
71GnRH signaling pathway_Homo sapiens_hsa049120.90692352
72Influenza A_Homo sapiens_hsa051640.90270333
73Fatty acid degradation_Homo sapiens_hsa000710.87832328
74Estrogen signaling pathway_Homo sapiens_hsa049150.87104923
75Colorectal cancer_Homo sapiens_hsa052100.84704742
76Jak-STAT signaling pathway_Homo sapiens_hsa046300.84676469
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84520438
78mTOR signaling pathway_Homo sapiens_hsa041500.84474049
79Malaria_Homo sapiens_hsa051440.82757793
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.82444982
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.81447403
82PPAR signaling pathway_Homo sapiens_hsa033200.80820751
83AMPK signaling pathway_Homo sapiens_hsa041520.80210563
84B cell receptor signaling pathway_Homo sapiens_hsa046620.79979599
85FoxO signaling pathway_Homo sapiens_hsa040680.79916353
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.79586231
87Maturity onset diabetes of the young_Homo sapiens_hsa049500.77975812
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77079900
89Herpes simplex infection_Homo sapiens_hsa051680.75665344
90Sulfur metabolism_Homo sapiens_hsa009200.75597261
91Endocytosis_Homo sapiens_hsa041440.74845082
92Shigellosis_Homo sapiens_hsa051310.73975257
93Thyroid hormone signaling pathway_Homo sapiens_hsa049190.73828356
94Hepatitis C_Homo sapiens_hsa051600.73660774
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.73423692
96Glioma_Homo sapiens_hsa052140.73306128
97TGF-beta signaling pathway_Homo sapiens_hsa043500.71625949
98PI3K-Akt signaling pathway_Homo sapiens_hsa041510.70527445
99Tuberculosis_Homo sapiens_hsa051520.69499126
100Hematopoietic cell lineage_Homo sapiens_hsa046400.69366012
101Intestinal immune network for IgA production_Homo sapiens_hsa046720.67539359
102HIF-1 signaling pathway_Homo sapiens_hsa040660.66989687
103Renin-angiotensin system_Homo sapiens_hsa046140.66461893
104Pertussis_Homo sapiens_hsa051330.66376025
105Arginine biosynthesis_Homo sapiens_hsa002200.65348731
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.65262559
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.65235760
108Cyanoamino acid metabolism_Homo sapiens_hsa004600.64713804
109Tryptophan metabolism_Homo sapiens_hsa003800.64384061
110N-Glycan biosynthesis_Homo sapiens_hsa005100.62743518
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61907303
112p53 signaling pathway_Homo sapiens_hsa041150.61580138
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60942865
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60937360
115Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60755186
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60751019
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.60475588
118Lysosome_Homo sapiens_hsa041420.60419827
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.60210302
120Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59524144
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58699915
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58334475
123Chemokine signaling pathway_Homo sapiens_hsa040620.57794756
124Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56765405
125Pathways in cancer_Homo sapiens_hsa052000.55764544
126ABC transporters_Homo sapiens_hsa020100.55469023
127Cell cycle_Homo sapiens_hsa041100.54871377
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54363184
129Salmonella infection_Homo sapiens_hsa051320.54084585
130Melanoma_Homo sapiens_hsa052180.53958765
131Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.53629188
132Long-term potentiation_Homo sapiens_hsa047200.52626605
133Phenylalanine metabolism_Homo sapiens_hsa003600.47157586
134Vibrio cholerae infection_Homo sapiens_hsa051100.46817128
135Glucagon signaling pathway_Homo sapiens_hsa049220.46777649
136RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46394214

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