FAM122B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)8.14285851
2polyketide metabolic process (GO:0030638)8.14285851
3doxorubicin metabolic process (GO:0044598)8.14285851
4protein localization to kinetochore (GO:0034501)6.87585992
5mitotic sister chromatid cohesion (GO:0007064)6.08727229
6regulation of telomere maintenance via telomerase (GO:0032210)5.84397349
7maintenance of protein location in nucleus (GO:0051457)5.72833235
8negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)5.67294186
9regulation of nuclear cell cycle DNA replication (GO:0033262)5.52835028
10mitotic sister chromatid segregation (GO:0000070)5.49862056
11protein localization to chromosome, centromeric region (GO:0071459)5.40719822
12DNA topological change (GO:0006265)5.32577623
13negative regulation of cell cycle G2/M phase transition (GO:1902750)5.19746989
14regulation of mammary gland epithelial cell proliferation (GO:0033599)5.16172884
15DNA replication-dependent nucleosome assembly (GO:0006335)5.16022089
16DNA replication-dependent nucleosome organization (GO:0034723)5.16022089
17aminoglycoside antibiotic metabolic process (GO:0030647)5.12901614
18somite rostral/caudal axis specification (GO:0032525)5.02294716
19histone H4-K12 acetylation (GO:0043983)5.00703429
20negative regulation of epidermis development (GO:0045683)4.99145872
21nuclear pore complex assembly (GO:0051292)4.97077082
22regulation of response to osmotic stress (GO:0047484)4.95196939
23histone H4-K5 acetylation (GO:0043981)4.80813185
24histone H4-K8 acetylation (GO:0043982)4.80813185
25negative regulation of telomerase activity (GO:0051974)4.79283756
26negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)4.76170987
27sister chromatid segregation (GO:0000819)4.74750045
28rRNA transcription (GO:0009303)4.70141159
29metaphase plate congression (GO:0051310)4.68212213
30DNA replication checkpoint (GO:0000076)4.66188441
31nuclear pore organization (GO:0006999)4.48320743
32heterochromatin organization (GO:0070828)4.37501954
33establishment of chromosome localization (GO:0051303)4.35772415
34muscle organ morphogenesis (GO:0048644)4.32938944
35positive regulation of DNA-dependent DNA replication (GO:2000105)4.30838246
36telomere maintenance via semi-conservative replication (GO:0032201)4.30193529
37negative regulation of telomere maintenance (GO:0032205)4.29402133
38regulation of MHC class I biosynthetic process (GO:0045343)4.18682658
39mitotic chromosome condensation (GO:0007076)4.18532863
40DNA strand elongation involved in DNA replication (GO:0006271)4.18166379
41chromatin assembly (GO:0031497)4.17981156
42kinetochore organization (GO:0051383)4.10821542
43notochord development (GO:0030903)4.09798978
44DNA strand elongation (GO:0022616)4.01683870
45cell fate commitment involved in formation of primary germ layer (GO:0060795)3.98434420
46rRNA methylation (GO:0031167)3.95200248
47regulation of sister chromatid cohesion (GO:0007063)3.91739747
48regulation of translation in response to stress (GO:0043555)3.91666372
49positive regulation of chromosome segregation (GO:0051984)3.90758319
50negative regulation of epidermal cell differentiation (GO:0045605)3.87079840
51mitotic recombination (GO:0006312)3.86805563
52regulation of chromosome segregation (GO:0051983)3.85686167
53regulation of mitotic spindle organization (GO:0060236)3.83341754
54regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.82611511
55DNA ligation (GO:0006266)3.82012761
56telomere maintenance via recombination (GO:0000722)3.81420085
57positive regulation of mitotic sister chromatid separation (GO:1901970)3.81045472
58positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.81045472
59positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.81045472
60DNA unwinding involved in DNA replication (GO:0006268)3.79587733
61CENP-A containing nucleosome assembly (GO:0034080)3.78288045
62pore complex assembly (GO:0046931)3.77000544
63regulation of centriole replication (GO:0046599)3.72314737
64rRNA modification (GO:0000154)3.71951349
65chromosome segregation (GO:0007059)3.69959022
66histone H4-K16 acetylation (GO:0043984)3.68362290
67regulation of telomere maintenance (GO:0032204)3.63597183
68sister chromatid cohesion (GO:0007062)3.63353005
69pre-miRNA processing (GO:0031054)3.63040535
70intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)3.62933666
71spindle checkpoint (GO:0031577)3.61656927
72membrane disassembly (GO:0030397)3.59387536
73regulation of histone H3-K27 methylation (GO:0061085)3.58356674
74chromatin remodeling at centromere (GO:0031055)3.58265615
75mitotic spindle checkpoint (GO:0071174)3.57760583
76DNA duplex unwinding (GO:0032508)3.53219039
77DNA geometric change (GO:0032392)3.50183255
78regulation of apoptotic process involved in morphogenesis (GO:1902337)3.48163758
79negative regulation of chromosome segregation (GO:0051985)3.46238541
80regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.44912059
81purine nucleobase biosynthetic process (GO:0009113)3.44176661
82IMP biosynthetic process (GO:0006188)3.44006189
83regulation of mitotic sister chromatid separation (GO:0010965)3.43934883
84regulation of mitotic sister chromatid segregation (GO:0033047)3.43934883
85regulation of sister chromatid segregation (GO:0033045)3.43934883
86mitotic spindle assembly checkpoint (GO:0007094)3.42712488
87regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.42154897
88regulation of mitotic metaphase/anaphase transition (GO:0030071)3.42154897
89nucleoside transmembrane transport (GO:1901642)3.40909557
90branching involved in mammary gland duct morphogenesis (GO:0060444)3.40325198
91interferon-gamma production (GO:0032609)3.40046280
92DNA packaging (GO:0006323)3.39873923
93DNA replication initiation (GO:0006270)3.38276110
94formation of translation preinitiation complex (GO:0001731)3.38036594
95negative regulation of sister chromatid segregation (GO:0033046)3.37860267
96negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.37860267
97negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.37860267
98negative regulation of mitotic sister chromatid segregation (GO:0033048)3.37860267
99negative regulation of mitotic sister chromatid separation (GO:2000816)3.37860267
100regulation of cilium movement (GO:0003352)3.37146319
101spindle assembly checkpoint (GO:0071173)3.36665820
102meiotic chromosome segregation (GO:0045132)3.36500115
103regulation of gene silencing by RNA (GO:0060966)3.36095454
104regulation of posttranscriptional gene silencing (GO:0060147)3.36095454
105regulation of gene silencing by miRNA (GO:0060964)3.36095454
106mitotic G2/M transition checkpoint (GO:0044818)3.35918943
107negative regulation of mRNA metabolic process (GO:1903312)3.34653729
108DNA replication-independent nucleosome organization (GO:0034724)3.34053894
109DNA replication-independent nucleosome assembly (GO:0006336)3.34053894
110regulation of DNA endoreduplication (GO:0032875)3.31800665
111establishment of integrated proviral latency (GO:0075713)3.30094808
112regulation of spindle organization (GO:0090224)3.29399648
113cytidine metabolic process (GO:0046087)3.28956385
114cytidine catabolic process (GO:0006216)3.28956385
115cytidine deamination (GO:0009972)3.28956385
116regulation of double-strand break repair (GO:2000779)3.26057645
117negative regulation of DNA repair (GO:0045738)3.24759028
118quinone metabolic process (GO:1901661)3.22298245
119cullin deneddylation (GO:0010388)3.21434452
120kinetochore assembly (GO:0051382)3.20593560
121negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.19845845
122attachment of spindle microtubules to kinetochore (GO:0008608)3.19731261
123mRNA stabilization (GO:0048255)3.19542486
124RNA stabilization (GO:0043489)3.19542486
125trophectodermal cell differentiation (GO:0001829)3.18577383
126phenol-containing compound catabolic process (GO:0019336)3.17803373
127regulation of centrosome cycle (GO:0046605)3.17179502
128protein localization to chromosome (GO:0034502)3.17108395
129response to dietary excess (GO:0002021)3.16644003
130regulation of telomerase activity (GO:0051972)3.15166682
131histone exchange (GO:0043486)3.13429158
132maintenance of protein localization in organelle (GO:0072595)3.12286637
133ribosome biogenesis (GO:0042254)3.10417979
134DNA synthesis involved in DNA repair (GO:0000731)3.09984557
135negative regulation of mRNA processing (GO:0050686)3.08171937
136double-strand break repair via nonhomologous end joining (GO:0006303)3.07951049
137non-recombinational repair (GO:0000726)3.07951049
138positive regulation of protein deacetylation (GO:0090312)3.05810554
139histone phosphorylation (GO:0016572)3.04713253
140nucleobase biosynthetic process (GO:0046112)3.03271344
141spindle assembly (GO:0051225)3.03221375
142negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.02890556
143intestinal epithelial cell development (GO:0060576)3.01701393
144regulation of DNA-dependent DNA replication (GO:0090329)2.98303213
145primitive streak formation (GO:0090009)2.98139500
146regulation of RNA export from nucleus (GO:0046831)2.97986304
147IMP metabolic process (GO:0046040)2.96039958
148regulation of double-strand break repair via homologous recombination (GO:0010569)2.95389318
149mitotic nuclear envelope disassembly (GO:0007077)2.95052110
150negative regulation of gene silencing (GO:0060969)2.93965651
151V(D)J recombination (GO:0033151)2.92155676
152positive regulation of histone H3-K4 methylation (GO:0051571)2.91772970
153nuclear envelope organization (GO:0006998)2.91647802
154N-terminal protein amino acid acetylation (GO:0006474)2.90464907
155chromatin assembly or disassembly (GO:0006333)2.90023781
156DNA conformation change (GO:0071103)2.89194822
157hormone catabolic process (GO:0042447)2.89142784
158coenzyme catabolic process (GO:0009109)2.87068673
159regulation of centrosome duplication (GO:0010824)2.86637465
1603-UTR-mediated mRNA stabilization (GO:0070935)2.86035735
161chromosome condensation (GO:0030261)2.85142511
162negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.84855130
163regulation of translational fidelity (GO:0006450)2.84282976
164DNA damage response, detection of DNA damage (GO:0042769)2.83315071
165regulation of odontogenesis of dentin-containing tooth (GO:0042487)2.82901447
166mitotic metaphase plate congression (GO:0007080)2.82533000
167protein deneddylation (GO:0000338)2.82435422
168positive regulation of defense response to virus by host (GO:0002230)2.82165068
169DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.80542366
170regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.77413272
171maternal placenta development (GO:0001893)2.74972812
172nuclear envelope disassembly (GO:0051081)2.70083487

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.94489988
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse5.56092004
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse5.56092004
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse5.56092004
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.51433595
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.67972439
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.56778086
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.42438262
9NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.82879132
10POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.78567863
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.78294092
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.73605126
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.67170448
14* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.60049642
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.45785807
16NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.43342917
17SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.43163896
18TCF3_18692474_ChIP-Seq_MESCs_Mouse2.28037853
19TCF3_18692474_ChIP-Seq_MEFs_Mouse2.27350450
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.25544998
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12550796
22MYC_19079543_ChIP-ChIP_MESCs_Mouse2.09884499
23RBPJ_22232070_ChIP-Seq_NCS_Mouse2.03102349
24SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.02661079
25* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.98344681
26ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.97187184
27MYC_19030024_ChIP-ChIP_MESCs_Mouse1.95123294
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89323735
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.85621225
30NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.83656013
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.82010993
32DCP1A_22483619_ChIP-Seq_HELA_Human1.80502853
33NANOG_18555785_ChIP-Seq_MESCs_Mouse1.78759528
34NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.78323871
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77357894
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.73958755
37POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.70333300
38KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.68023762
39CREB1_15753290_ChIP-ChIP_HEK293T_Human1.66750964
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.64638453
41MYC_18358816_ChIP-ChIP_MESCs_Mouse1.63356413
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.62676845
43ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.62048685
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.60232974
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.59755488
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.58960387
47ELK1_19687146_ChIP-ChIP_HELA_Human1.58337051
48ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.56980256
49SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.55608009
50KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.55406729
51CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.55133940
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54617762
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54084999
54CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.52252402
55EST1_17652178_ChIP-ChIP_JURKAT_Human1.51984306
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51296806
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.51179356
58HIF1A_21447827_ChIP-Seq_MCF-7_Human1.50502233
59POU5F1_16518401_ChIP-PET_MESCs_Mouse1.46851109
60NANOG_18692474_ChIP-Seq_MEFs_Mouse1.46041515
61MYC_22102868_ChIP-Seq_BL_Human1.46011451
62IRF1_19129219_ChIP-ChIP_H3396_Human1.44780969
63TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.40624228
64NANOG_18692474_ChIP-Seq_MESCs_Mouse1.40218059
65NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.39903524
66AR_21909140_ChIP-Seq_LNCAP_Human1.38846166
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34845011
68YY1_21170310_ChIP-Seq_MESCs_Mouse1.30218689
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25498413
70POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.25368920
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24323712
72NELFA_20434984_ChIP-Seq_ESCs_Mouse1.23024536
73SOX2_18692474_ChIP-Seq_MESCs_Mouse1.21768444
74CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.21393844
75OCT4_18692474_ChIP-Seq_MEFs_Mouse1.20664725
76E2F1_18555785_ChIP-Seq_MESCs_Mouse1.20422975
77CHD1_26751641_Chip-Seq_LNCaP_Human1.20030180
78SOX2_18692474_ChIP-Seq_MEFs_Mouse1.18964002
79TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18747589
80NANOG_21062744_ChIP-ChIP_HESCs_Human1.18215004
81PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.17843920
82KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14826357
83XRN2_22483619_ChIP-Seq_HELA_Human1.14567637
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14207175
85MYB_21317192_ChIP-Seq_ERMYB_Mouse1.12033178
86FOXP3_21729870_ChIP-Seq_TREG_Human1.11291845
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07070575
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05036574
89ETS1_20019798_ChIP-Seq_JURKAT_Human1.05033152
90MYCN_18555785_ChIP-Seq_MESCs_Mouse1.04473114
91KDM5A_27292631_Chip-Seq_BREAST_Human1.03627533
92GATA1_22025678_ChIP-Seq_K562_Human1.02510538
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00849340
94NANOG_16153702_ChIP-ChIP_HESCs_Human0.99549348
95JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97591297
96TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96980098
97NOTCH1_21737748_ChIP-Seq_TLL_Human0.96890664
98SPI1_23547873_ChIP-Seq_NB4_Human0.96368810
99E2F1_17053090_ChIP-ChIP_MCF-7_Human0.95746039
100GABP_17652178_ChIP-ChIP_JURKAT_Human0.95487283
101EGR1_19374776_ChIP-ChIP_THP-1_Human0.94512331
102E2F1_21310950_ChIP-Seq_MCF-7_Human0.94048238
103SALL1_21062744_ChIP-ChIP_HESCs_Human0.93091942
104NANOG_16518401_ChIP-PET_MESCs_Mouse0.92722281
105TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92570434
106ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.92286215
107E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91491341
108MYB_26560356_Chip-Seq_TH1_Human0.90716721
109KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.90439192
110* NCOR1_26117541_ChIP-Seq_K562_Human0.89946591
111ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89780805
112POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.89768714
113SCL_19346495_ChIP-Seq_HPC-7_Human0.89015264
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.88760421
115VDR_23849224_ChIP-Seq_CD4+_Human0.88303821
116TTF2_22483619_ChIP-Seq_HELA_Human0.88070992
117TP53_22127205_ChIP-Seq_IMR90_Human0.87832047
118ZFP281_18757296_ChIP-ChIP_E14_Mouse0.86961072
119ZNF263_19887448_ChIP-Seq_K562_Human0.86204228
120POU5F1_16153702_ChIP-ChIP_HESCs_Human0.85882812
121MYB_26560356_Chip-Seq_TH2_Human0.84031400
122ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.83300243
123GATA1_22383799_ChIP-Seq_G1ME_Mouse0.83277603
124TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.82561249
125CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.82433806
126CIITA_25753668_ChIP-Seq_RAJI_Human0.82279949
127PKCTHETA_26484144_Chip-Seq_BREAST_Human0.82089126
128ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81762016
129SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.81720886
130* GABP_19822575_ChIP-Seq_HepG2_Human0.81613178
131VDR_21846776_ChIP-Seq_THP-1_Human0.80418182
132SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.80091778
133KAP1_27257070_Chip-Seq_ESCs_Mouse0.79805853
134TFEB_21752829_ChIP-Seq_HELA_Human0.79137131
135DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.79104273
136SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.76814118
137PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.76026975
138BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.75341852
139TCF7_22412390_ChIP-Seq_EML_Mouse0.75101999
140SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.74870536
141MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.74709054
142TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.74165779
143RUNX1_22412390_ChIP-Seq_EML_Mouse0.74001804
144KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.73979035
145EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.73970376

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.02320363
2MP0004264_abnormal_extraembryonic_tissu4.01007721
3MP0004957_abnormal_blastocyst_morpholog3.54332109
4MP0002254_reproductive_system_inflammat3.43275823
5MP0006292_abnormal_olfactory_placode3.42732291
6MP0003011_delayed_dark_adaptation3.31104467
7MP0003890_abnormal_embryonic-extraembry3.06822710
8MP0005075_abnormal_melanosome_morpholog2.91126319
9MP0003121_genomic_imprinting2.58824262
10MP0003077_abnormal_cell_cycle2.47432973
11MP0010352_gastrointestinal_tract_polyps2.42697826
12MP0010094_abnormal_chromosome_stability2.38851097
13MP0003122_maternal_imprinting2.37746979
14MP0005499_abnormal_olfactory_system2.37338878
15MP0005394_taste/olfaction_phenotype2.37338878
16MP0004185_abnormal_adipocyte_glucose2.31538145
17MP0010234_abnormal_vibrissa_follicle2.30878009
18MP0003111_abnormal_nucleus_morphology2.24891874
19MP0004808_abnormal_hematopoietic_stem2.20408194
20MP0001672_abnormal_embryogenesis/_devel2.16427567
21MP0005380_embryogenesis_phenotype2.16427567
22MP0005076_abnormal_cell_differentiation2.13087190
23MP0003693_abnormal_embryo_hatching2.04673632
24MP0002088_abnormal_embryonic_growth/wei1.99450070
25MP0003984_embryonic_growth_retardation1.99141203
26MP0010307_abnormal_tumor_latency1.97272037
27MP0003705_abnormal_hypodermis_morpholog1.96861478
28MP0004858_abnormal_nervous_system1.95848515
29MP0002396_abnormal_hematopoietic_system1.94991411
30MP0000350_abnormal_cell_proliferation1.93010748
31MP0009697_abnormal_copulation1.92918550
32MP0003123_paternal_imprinting1.91443909
33MP0002332_abnormal_exercise_endurance1.91274758
34MP0002009_preneoplasia1.87385414
35MP0002653_abnormal_ependyma_morphology1.81258668
36MP0008932_abnormal_embryonic_tissue1.71347293
37MP0001293_anophthalmia1.70540856
38MP0003938_abnormal_ear_development1.64494756
39MP0006035_abnormal_mitochondrial_morpho1.64233441
40MP0002086_abnormal_extraembryonic_tissu1.62689501
41MP0002085_abnormal_embryonic_tissue1.62043251
42MP0001849_ear_inflammation1.58426940
43MP0001730_embryonic_growth_arrest1.58125069
44MP0003943_abnormal_hepatobiliary_system1.52791735
45MP0002084_abnormal_developmental_patter1.50981771
46MP0009672_abnormal_birth_weight1.48327013
47MP0004197_abnormal_fetal_growth/weight/1.48136645
48MP0010030_abnormal_orbit_morphology1.42986766
49MP0001697_abnormal_embryo_size1.40690086
50MP0000703_abnormal_thymus_morphology1.39960318
51MP0005464_abnormal_platelet_physiology1.39443758
52MP0002127_abnormal_cardiovascular_syste1.38336124
53MP0005257_abnormal_intraocular_pressure1.38282041
54MP0002092_abnormal_eye_morphology1.36210098
55MP0000490_abnormal_crypts_of1.30474029
56MP0008995_early_reproductive_senescence1.29764758
57MP0000678_abnormal_parathyroid_gland1.23831552
58MP0006082_CNS_inflammation1.22633716
59MP0008007_abnormal_cellular_replicative1.22546406
60MP0002277_abnormal_respiratory_mucosa1.21431521
61MP0005666_abnormal_adipose_tissue1.20901231
62MP0005174_abnormal_tail_pigmentation1.20426156
63MP0003315_abnormal_perineum_morphology1.20128082
64MP0000762_abnormal_tongue_morphology1.19322813
65MP0002080_prenatal_lethality1.18867351
66MP0002932_abnormal_joint_morphology1.18694597
67MP0005621_abnormal_cell_physiology1.18148476
68MP0000313_abnormal_cell_death1.17666165
69MP0003763_abnormal_thymus_physiology1.17587250
70MP0004133_heterotaxia1.17474016
71MP0002398_abnormal_bone_marrow1.15181979
72MP0001348_abnormal_lacrimal_gland1.14819229
73MP0003183_abnormal_peptide_metabolism1.13081038
74MP0005451_abnormal_body_composition1.12934247
75MP0003787_abnormal_imprinting1.08916415
76MP0002796_impaired_skin_barrier1.08438748
77MP0008789_abnormal_olfactory_epithelium1.07431927
78MP0005266_abnormal_metabolism1.06813637
79MP0000428_abnormal_craniofacial_morphol1.06112695
80MP0003937_abnormal_limbs/digits/tail_de1.05929227
81MP0000432_abnormal_head_morphology1.04965945
82MP0002114_abnormal_axial_skeleton1.04879371
83MP0008058_abnormal_DNA_repair1.04198174
84MP0000049_abnormal_middle_ear1.03798649
85MP0001346_abnormal_lacrimal_gland1.01634560
86MP0008004_abnormal_stomach_pH1.01257372
87MP0005501_abnormal_skin_physiology1.00723566
88MP0003119_abnormal_digestive_system1.00679516
89MP0002233_abnormal_nose_morphology1.00369015
90MP0000537_abnormal_urethra_morphology0.99313510
91MP0002166_altered_tumor_susceptibility0.98678556
92MP0003935_abnormal_craniofacial_develop0.98444518
93MP0002925_abnormal_cardiovascular_devel0.95739645
94MP0003755_abnormal_palate_morphology0.95130902
95MP0004381_abnormal_hair_follicle0.94984768
96MP0005623_abnormal_meninges_morphology0.93994114
97MP0002006_tumorigenesis0.93248335
98MP0009703_decreased_birth_body0.93122776
99MP0003718_maternal_effect0.92843262
100MP0003656_abnormal_erythrocyte_physiolo0.91286611
101MP0008770_decreased_survivor_rate0.90685448
102MP0002697_abnormal_eye_size0.90404467
103MP0002210_abnormal_sex_determination0.89158987
104MP0002722_abnormal_immune_system0.87442478
105MP0003950_abnormal_plasma_membrane0.83523814
106MP0001929_abnormal_gametogenesis0.83494841
107MP0002019_abnormal_tumor_incidence0.82798230
108MP0002970_abnormal_white_adipose0.82239224
109MP0000383_abnormal_hair_follicle0.81383613
110MP0005023_abnormal_wound_healing0.81312941
111MP0005397_hematopoietic_system_phenotyp0.81285385
112MP0001545_abnormal_hematopoietic_system0.81285385
113MP0001286_abnormal_eye_development0.80936796
114MP0000689_abnormal_spleen_morphology0.80459681
115MP0009278_abnormal_bone_marrow0.79798180
116MP0003221_abnormal_cardiomyocyte_apopto0.77769720
117MP0003566_abnormal_cell_adhesion0.77152721
118MP0005384_cellular_phenotype0.76179248
119MP0002249_abnormal_larynx_morphology0.75907141
120MP0003806_abnormal_nucleotide_metabolis0.75456643
121MP0005391_vision/eye_phenotype0.75149066
122MP0003786_premature_aging0.74580598
123MP0000015_abnormal_ear_pigmentation0.74402576
124MP0000358_abnormal_cell_content/0.73948439
125MP0003136_yellow_coat_color0.72433536
126MP0001851_eye_inflammation0.72210083
127MP0001661_extended_life_span0.71759311
128MP0002429_abnormal_blood_cell0.71723773
129MP0000653_abnormal_sex_gland0.70552289
130MP0001853_heart_inflammation0.70257436
131MP0008961_abnormal_basal_metabolism0.69933433
132MP0003448_altered_tumor_morphology0.69460393
133MP0001881_abnormal_mammary_gland0.69261771
134MP0002111_abnormal_tail_morphology0.67981291
135MP0005508_abnormal_skeleton_morphology0.67561915
136MP0001915_intracranial_hemorrhage0.65262639
137MP0010678_abnormal_skin_adnexa0.63754035
138MP0000377_abnormal_hair_follicle0.63209703
139MP0002269_muscular_atrophy0.62831061
140MP0003699_abnormal_female_reproductive0.62797910
141MP0002751_abnormal_autonomic_nervous0.62499209
142MP0003861_abnormal_nervous_system0.61749224
143MP0002116_abnormal_craniofacial_bone0.61203464
144MP0003828_pulmonary_edema0.61188163
145MP0002877_abnormal_melanocyte_morpholog0.60196681
146MP0001216_abnormal_epidermal_layer0.60071600
147MP0003453_abnormal_keratinocyte_physiol0.59912112
148MP0001145_abnormal_male_reproductive0.59905026
149MP0010630_abnormal_cardiac_muscle0.59600125
150MP0000627_abnormal_mammary_gland0.58752449
151MP0003172_abnormal_lysosome_physiology0.58385103
152MP0008260_abnormal_autophagy0.57763004

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)6.48557099
2Hypochromic microcytic anemia (HP:0004840)6.20167091
3Multiple enchondromatosis (HP:0005701)4.69420225
4Hepatoblastoma (HP:0002884)4.68927473
5Ependymoma (HP:0002888)4.61331093
6Rib fusion (HP:0000902)4.55639004
7Chromosomal breakage induced by crosslinking agents (HP:0003221)4.06136317
8Nephroblastoma (Wilms tumor) (HP:0002667)3.91334436
9Increased nuchal translucency (HP:0010880)3.82904461
10Rhabdomyosarcoma (HP:0002859)3.80025070
11Chromsome breakage (HP:0040012)3.74619917
12Ankyloglossia (HP:0010296)3.69753923
13Neoplasm of striated muscle (HP:0009728)3.69453571
14Abnormality of the lower motor neuron (HP:0002366)3.68262758
15Embryonal renal neoplasm (HP:0011794)3.65456171
16Rectal fistula (HP:0100590)3.39704988
17Rectovaginal fistula (HP:0000143)3.39704988
18Fused cervical vertebrae (HP:0002949)3.25414643
19Abnormality of the salivary glands (HP:0010286)3.24245948
20Abnormality of the astrocytes (HP:0100707)3.23007751
21Astrocytoma (HP:0009592)3.23007751
22Abnormal lung lobation (HP:0002101)3.21656124
23Abnormality of oral frenula (HP:0000190)3.15435420
24Meckel diverticulum (HP:0002245)3.12259600
25Partial duplication of thumb phalanx (HP:0009944)3.07072751
26Intestinal fistula (HP:0100819)3.04014793
27Aplasia/hypoplasia of the humerus (HP:0006507)2.98459630
28Abnormality of the ileum (HP:0001549)2.95328480
29Aplasia/Hypoplasia of the uvula (HP:0010293)2.91473111
30Short humerus (HP:0005792)2.88660638
31Impulsivity (HP:0100710)2.86395711
32Cafe-au-lait spot (HP:0000957)2.84826481
33Reticulocytopenia (HP:0001896)2.83862346
34Aplasia/Hypoplasia of the fovea (HP:0008060)2.81053724
35Hypoplasia of the fovea (HP:0007750)2.81053724
36Vaginal fistula (HP:0004320)2.79830050
37Abnormal umbilical cord blood vessels (HP:0011403)2.78971843
38Single umbilical artery (HP:0001195)2.78971843
39Abnormality of the fetal cardiovascular system (HP:0010948)2.78971843
40Amyotrophic lateral sclerosis (HP:0007354)2.75961163
41Supernumerary spleens (HP:0009799)2.75419365
42Transitional cell carcinoma of the bladder (HP:0006740)2.74474227
43Aplasia/Hypoplasia of the sacrum (HP:0008517)2.73261206
44Partial duplication of the phalanx of hand (HP:0009999)2.70215541
45Trismus (HP:0000211)2.70151393
46Abnormality of chromosome segregation (HP:0002916)2.66756949
47Sensory axonal neuropathy (HP:0003390)2.60336887
48Cholecystitis (HP:0001082)2.60179741
49Abnormal gallbladder physiology (HP:0012438)2.60179741
50Uterine leiomyosarcoma (HP:0002891)2.59700299
51Leiomyosarcoma (HP:0100243)2.59700299
52Malignant gastrointestinal tract tumors (HP:0006749)2.59253728
53Gastrointestinal carcinoma (HP:0002672)2.59253728
54Ragged-red muscle fibers (HP:0003200)2.58445386
55Hypochromic anemia (HP:0001931)2.57564201
56Birth length less than 3rd percentile (HP:0003561)2.56499387
57Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.55571959
58Small intestinal stenosis (HP:0012848)2.54229690
59Duodenal stenosis (HP:0100867)2.54229690
60Proximal placement of thumb (HP:0009623)2.53943561
61Microvesicular hepatic steatosis (HP:0001414)2.53664822
62Preauricular skin tag (HP:0000384)2.53580094
63Shawl scrotum (HP:0000049)2.49287969
64Bifid tongue (HP:0010297)2.47893694
65Anomalous pulmonary venous return (HP:0010772)2.47448049
66Bladder carcinoma (HP:0002862)2.44868487
67Bladder neoplasm (HP:0009725)2.44868487
68Deviation of the thumb (HP:0009603)2.43595533
69Abnormal platelet volume (HP:0011876)2.43248838
70Glioma (HP:0009733)2.42181381
71Testicular atrophy (HP:0000029)2.41633677
72Increased mean platelet volume (HP:0011877)2.41157031
73Large earlobe (HP:0009748)2.40115758
74Deep philtrum (HP:0002002)2.39143999
75Asymmetry of the thorax (HP:0001555)2.39138321
76Horizontal nystagmus (HP:0000666)2.39002795
77Progressive external ophthalmoplegia (HP:0000590)2.38209289
78Medulloblastoma (HP:0002885)2.35385024
79Absent radius (HP:0003974)2.31748028
80Ectopic kidney (HP:0000086)2.29123897
81Macroorchidism (HP:0000053)2.24707597
82Clubbing of toes (HP:0100760)2.23701517
83Abnormal cartilage morphology (HP:0002763)2.23433925
84Abnormality of the fingertips (HP:0001211)2.23395446
85Skin tags (HP:0010609)2.23361434
86Preauricular pit (HP:0004467)2.22752824
87Periauricular skin pits (HP:0100277)2.22752824
88Nasolacrimal duct obstruction (HP:0000579)2.18702304
89Neoplasm of the oral cavity (HP:0100649)2.18604176
90Sandal gap (HP:0001852)2.16769054
91Abnormality of chromosome stability (HP:0003220)2.16177648
92Choanal atresia (HP:0000453)2.16165822
93Hyperinsulinemic hypoglycemia (HP:0000825)2.16028572
94Abnormality of the pulmonary veins (HP:0011718)2.14910704
95Aplasia/Hypoplasia of the sternum (HP:0006714)2.14663377
96Abnormality of the phalanges of the hallux (HP:0010057)2.14558824
97Reduced antithrombin III activity (HP:0001976)2.14215846
98Acute myeloid leukemia (HP:0004808)2.13402193
99Prolonged bleeding time (HP:0003010)2.13204875
100Abnormality of the umbilical cord (HP:0010881)2.12183047
101Abnormality of the preputium (HP:0100587)2.11191994
102Myelodysplasia (HP:0002863)2.10605347
103Ovarian neoplasm (HP:0100615)2.10392531
104Unilateral renal agenesis (HP:0000122)2.10284480
105Volvulus (HP:0002580)2.09599536
106Glossoptosis (HP:0000162)2.09270871
107Abnormality of the duodenum (HP:0002246)2.08708843
108Abnormality of the distal phalanx of the thumb (HP:0009617)2.08336724
109Uterine neoplasm (HP:0010784)2.08006655
110Supernumerary ribs (HP:0005815)2.07837974
111Aqueductal stenosis (HP:0002410)2.06658610
112Orthostatic hypotension (HP:0001278)2.06031811
113Atresia of the external auditory canal (HP:0000413)2.05619738
114Generalized hypotonia (HP:0001290)2.04538432
115Hypopigmentation of the fundus (HP:0007894)2.04255779
116Progressive muscle weakness (HP:0003323)2.03547138
117Short 5th finger (HP:0009237)2.02805918
118Aplasia involving forearm bones (HP:0009822)2.02515122
119Absent forearm bone (HP:0003953)2.02515122
120Missing ribs (HP:0000921)2.02011495
121Combined immunodeficiency (HP:0005387)2.01876744
122Neoplasm of the colon (HP:0100273)2.01669522
123Abnormality of the musculature of the hand (HP:0001421)2.01471688
124Difficulty running (HP:0009046)2.01086000
125Truncal obesity (HP:0001956)2.00685981
126Low anterior hairline (HP:0000294)2.00410387
127Acute lymphatic leukemia (HP:0006721)1.99574195
128Renal duplication (HP:0000075)1.99251987
129Pendular nystagmus (HP:0012043)1.98010751
130Abnormality of the fovea (HP:0000493)1.97807099
131Short middle phalanx of the 5th finger (HP:0004220)1.97681716
132Supernumerary bones of the axial skeleton (HP:0009144)1.96297524
133Sloping forehead (HP:0000340)1.95149500
134Neoplasm of the adrenal cortex (HP:0100641)1.95112315
135Overlapping toe (HP:0001845)1.94371915
136Abnormality of glycolysis (HP:0004366)1.94325297
137Increased serum pyruvate (HP:0003542)1.94325297
138Biliary tract neoplasm (HP:0100574)1.93685375
139Prominent occiput (HP:0000269)1.93342494
140Duplication of thumb phalanx (HP:0009942)1.92883359
141Tongue fasciculations (HP:0001308)1.92392962
142Atrophy/Degeneration involving motor neurons (HP:0007373)1.90544537
143Panhypogammaglobulinemia (HP:0003139)1.90537756
144Duplicated collecting system (HP:0000081)1.90355394
145Cutaneous melanoma (HP:0012056)1.88932385
146Vertebral fusion (HP:0002948)1.88930519
147Abnormality of small intestinal villus morphology (HP:0011472)1.88426843
148Villous atrophy (HP:0011473)1.88426843
149Papillary thyroid carcinoma (HP:0002895)1.87637522
150Broad alveolar ridges (HP:0000187)1.87480996
151Malignant neoplasm of the central nervous system (HP:0100836)1.87349074
152Basal cell carcinoma (HP:0002671)1.87054018
153Increased density of long bones (HP:0006392)1.86785480
154Urethral obstruction (HP:0000796)1.85958017
155Triphalangeal thumb (HP:0001199)1.85652883
156Abnormality of the labia minora (HP:0012880)1.85537720
157Breast hypoplasia (HP:0003187)1.85282577
158Embryonal neoplasm (HP:0002898)1.85150382
159Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.84727816
160Skin pits (HP:0100276)1.84615095
161Premature ovarian failure (HP:0008209)1.83630628
162Pseudobulbar signs (HP:0002200)1.83628697
163Absent thumb (HP:0009777)1.81942670
164Testicular neoplasm (HP:0010788)1.78396362
165Viral hepatitis (HP:0006562)1.77442303
166Fatigue (HP:0012378)1.74989934
167Micronodular cirrhosis (HP:0001413)1.74531694
168Obsessive-compulsive behavior (HP:0000722)1.72664968
169Lymphoma (HP:0002665)1.72624949
170Selective tooth agenesis (HP:0001592)1.68095366
171Dyschromatopsia (HP:0007641)1.68041115
172Ureteral duplication (HP:0000073)1.67998685
173Recurrent viral infections (HP:0004429)1.66842135
174Prominent nose (HP:0000448)1.65905021
175Thyroid carcinoma (HP:0002890)1.65775224
176Abnormality of the carotid arteries (HP:0005344)1.63833730

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK128.39426479
2GRK54.41261141
3GRK63.48897181
4ERN13.46968890
5TTK3.33995447
6STK102.83012248
7PBK2.79946637
8CSF1R2.78141341
9SMG12.69537645
10GRK12.44406875
11SIK32.40024021
12ADRBK22.32738286
13TYRO32.32041380
14TGFBR22.17089004
15TAF12.12754725
16WNK12.03647118
17PNCK2.03061624
18MATK1.99504878
19CDC71.96314128
20VRK21.95748308
21MAPK71.92800823
22CDK71.90644869
23MOS1.86749785
24GRK71.85905827
25TRIB31.82389930
26PKN21.79941640
27MKNK21.74591149
28PRPF4B1.66046355
29EPHA21.61735500
30TRIM281.61150747
31PLK31.60648905
32CHEK21.60624914
33WEE11.60405094
34NEK21.56765321
35PLK11.56116897
36PASK1.52715117
37BUB11.49923228
38SCYL21.49749847
39MST1R1.45865348
40PAK41.33515117
41TESK21.29601759
42RIPK41.25756222
43NTRK11.20796322
44RPS6KB21.18108696
45PRKG21.17209060
46CHEK11.17192888
47MAP3K101.09399626
48AKT31.04596306
49CDK61.04316199
50HIPK21.03005075
51CAMK41.01455461
52MARK21.01420090
53KSR10.96625667
54YES10.88576630
55LRRK20.88512063
56FGFR10.88355762
57SRPK10.87652000
58CDK90.86238013
59IRAK20.85654258
60ALK0.84965866
61AURKB0.80933394
62MAP2K30.80132462
63EIF2AK30.78965071
64BRSK20.78878362
65STK40.78161462
66ADRBK10.77080385
67CDK40.75978204
68MARK30.75813492
69NEK10.74659045
70CSK0.72895616
71NME20.72771701
72FGFR30.72210350
73AURKA0.70567473
74AKT20.69574606
75CDK20.68774251
76NEK60.66802390
77DYRK30.66773164
78MAP3K140.66468007
79MAP3K80.66414619
80ATM0.64247494
81FGFR20.63011540
82MTOR0.60889898
83MST40.59647373
84EIF2AK20.58354729
85SIK10.58335914
86BMX0.57241110
87RPS6KA40.55713708
88IRAK30.55603567
89PLK40.55203689
90LATS10.55089276
91LATS20.54593269
92TSSK60.54340798
93BMPR20.54322307
94MAP3K130.54019834
95PAK10.51787581
96BRAF0.49553101
97KSR20.49163819
98MELK0.49050127
99ITK0.48279559
100CDK10.47356410
101MKNK10.46652882
102STK240.46160153
103PRKCI0.45838902
104NUAK10.45813816
105STK390.45573586
106MAPK120.45391997
107ATR0.45302886
108DMPK0.43865938
109MAP3K90.41877260
110PRKD30.41745295
111CDK30.41665069
112CCNB10.41609449
113CAMK1G0.39025818
114CSNK1E0.37284984
115CLK10.35871950
116MAP2K60.35289976
117STK30.35085648
118MAPKAPK30.34580312
119EEF2K0.33958327
120UHMK10.33501125
121BRD40.33279027
122MAP2K40.32968233
123EPHB10.32416827
124MET0.31346703
125PTK60.31288524
126FLT30.31221620
127ILK0.29724074
128MAPK10.29521179
129PIM10.29052398
130MAPK100.28627438
131ACVR1B0.28408644
132PTK20.27856465
133TRPM70.27716237
134CDK150.27473730
135MAP3K70.26980672
136CDK11A0.26949747
137EIF2AK10.25694061
138IGF1R0.25492827
139MAPK140.25260779
140RPS6KB10.24836613
141GSK3B0.24830972
142PLK20.24801257
143BRSK10.24530176
144ERBB20.22326444
145CDK180.22135530
146CSNK1D0.22106729
147IKBKB0.21763171
148DYRK20.21149730
149CDK140.20010814
150MAPKAPK20.20002827
151ICK0.19982278
152CDK80.17523004
153BLK0.16133763
154INSR0.15523483

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.96401405
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.16714146
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006034.09520822
4DNA replication_Homo sapiens_hsa030303.07813674
5Mismatch repair_Homo sapiens_hsa034302.85517275
6RNA transport_Homo sapiens_hsa030132.62904794
7Cell cycle_Homo sapiens_hsa041102.62801857
8Homologous recombination_Homo sapiens_hsa034402.50276033
9Fructose and mannose metabolism_Homo sapiens_hsa000512.45729866
10Fanconi anemia pathway_Homo sapiens_hsa034602.38129458
11Arachidonic acid metabolism_Homo sapiens_hsa005902.05927688
12Spliceosome_Homo sapiens_hsa030401.96982159
13Linoleic acid metabolism_Homo sapiens_hsa005911.91452813
14mRNA surveillance pathway_Homo sapiens_hsa030151.85257113
15RNA degradation_Homo sapiens_hsa030181.80215893
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.79653324
17Ribosome_Homo sapiens_hsa030101.78782682
18Base excision repair_Homo sapiens_hsa034101.75774417
19Chronic myeloid leukemia_Homo sapiens_hsa052201.73455401
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.72595509
21Nucleotide excision repair_Homo sapiens_hsa034201.71404524
22One carbon pool by folate_Homo sapiens_hsa006701.69038851
23RNA polymerase_Homo sapiens_hsa030201.63872844
24p53 signaling pathway_Homo sapiens_hsa041151.63435429
25Galactose metabolism_Homo sapiens_hsa000521.54379399
26Thyroid cancer_Homo sapiens_hsa052161.52572728
27Basal transcription factors_Homo sapiens_hsa030221.48668602
28Non-homologous end-joining_Homo sapiens_hsa034501.47483357
29Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.32087919
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.25249466
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.23888587
32Endometrial cancer_Homo sapiens_hsa052131.21179834
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18094164
34Ether lipid metabolism_Homo sapiens_hsa005651.14813983
35mTOR signaling pathway_Homo sapiens_hsa041501.14468992
36Glioma_Homo sapiens_hsa052141.14156107
37Prostate cancer_Homo sapiens_hsa052151.13534255
38MicroRNAs in cancer_Homo sapiens_hsa052061.09528816
39B cell receptor signaling pathway_Homo sapiens_hsa046621.09177498
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.03194493
41Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.94718845
42Pyrimidine metabolism_Homo sapiens_hsa002400.93132613
43Cysteine and methionine metabolism_Homo sapiens_hsa002700.88596882
44Regulation of actin cytoskeleton_Homo sapiens_hsa048100.88293872
45Long-term potentiation_Homo sapiens_hsa047200.87016749
46Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85035943
47Pathways in cancer_Homo sapiens_hsa052000.84817651
48Hepatitis B_Homo sapiens_hsa051610.83822794
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.80038614
50Hippo signaling pathway_Homo sapiens_hsa043900.79978429
51Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77514236
52Basal cell carcinoma_Homo sapiens_hsa052170.76937585
53Viral carcinogenesis_Homo sapiens_hsa052030.76693907
54Folate biosynthesis_Homo sapiens_hsa007900.76414137
55Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74766527
56N-Glycan biosynthesis_Homo sapiens_hsa005100.72840987
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72411804
58Herpes simplex infection_Homo sapiens_hsa051680.71626307
59Ovarian steroidogenesis_Homo sapiens_hsa049130.70348881
60Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.70172419
61ErbB signaling pathway_Homo sapiens_hsa040120.68235600
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68043363
63Platelet activation_Homo sapiens_hsa046110.66652083
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.66579530
65Hedgehog signaling pathway_Homo sapiens_hsa043400.66408126
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64563436
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63253366
68Pentose phosphate pathway_Homo sapiens_hsa000300.62985527
69T cell receptor signaling pathway_Homo sapiens_hsa046600.62248699
70Other glycan degradation_Homo sapiens_hsa005110.62059878
71Notch signaling pathway_Homo sapiens_hsa043300.61855712
72HTLV-I infection_Homo sapiens_hsa051660.61422145
73Leukocyte transendothelial migration_Homo sapiens_hsa046700.61307085
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59697017
75Lysine degradation_Homo sapiens_hsa003100.59562036
76Acute myeloid leukemia_Homo sapiens_hsa052210.59415604
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.59357348
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59349233
79Tight junction_Homo sapiens_hsa045300.59268394
80Protein export_Homo sapiens_hsa030600.59089446
81Inositol phosphate metabolism_Homo sapiens_hsa005620.58458931
82Pancreatic cancer_Homo sapiens_hsa052120.57604580
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55647909
84Small cell lung cancer_Homo sapiens_hsa052220.55621735
85Non-small cell lung cancer_Homo sapiens_hsa052230.55526523
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.55345688
87Oocyte meiosis_Homo sapiens_hsa041140.55160121
88FoxO signaling pathway_Homo sapiens_hsa040680.53808908
89Measles_Homo sapiens_hsa051620.53787862
90HIF-1 signaling pathway_Homo sapiens_hsa040660.53587814
91Carbon metabolism_Homo sapiens_hsa012000.53199319
92Bladder cancer_Homo sapiens_hsa052190.52714183
93Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50441071
94Melanoma_Homo sapiens_hsa052180.49511770
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48781874
96Choline metabolism in cancer_Homo sapiens_hsa052310.48651836
97Primary immunodeficiency_Homo sapiens_hsa053400.48479724
98Shigellosis_Homo sapiens_hsa051310.48034175
99Melanogenesis_Homo sapiens_hsa049160.47677018
100Rap1 signaling pathway_Homo sapiens_hsa040150.46039580
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45946399
102Adherens junction_Homo sapiens_hsa045200.45339564
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.43417530
104Proteasome_Homo sapiens_hsa030500.41709815
105Apoptosis_Homo sapiens_hsa042100.40768842
106Pyruvate metabolism_Homo sapiens_hsa006200.40596226
107Regulation of autophagy_Homo sapiens_hsa041400.40544466
108Antigen processing and presentation_Homo sapiens_hsa046120.40534205
109Insulin signaling pathway_Homo sapiens_hsa049100.40231360
110Glycerophospholipid metabolism_Homo sapiens_hsa005640.40101729
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39736337
112Wnt signaling pathway_Homo sapiens_hsa043100.39729156
113PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39491607
114Proteoglycans in cancer_Homo sapiens_hsa052050.39479217
115Glucagon signaling pathway_Homo sapiens_hsa049220.39021824
116Glutathione metabolism_Homo sapiens_hsa004800.35707067
117TGF-beta signaling pathway_Homo sapiens_hsa043500.34887431
118Biosynthesis of amino acids_Homo sapiens_hsa012300.33991272
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33263539
120Colorectal cancer_Homo sapiens_hsa052100.32829858
121Epstein-Barr virus infection_Homo sapiens_hsa051690.32527783
122VEGF signaling pathway_Homo sapiens_hsa043700.31757913
123Gap junction_Homo sapiens_hsa045400.31720179
124Estrogen signaling pathway_Homo sapiens_hsa049150.31719393
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30931601
126NF-kappa B signaling pathway_Homo sapiens_hsa040640.29263790
127Chemical carcinogenesis_Homo sapiens_hsa052040.28930077
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.27682743
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.24328639
130Selenocompound metabolism_Homo sapiens_hsa004500.24318667
131Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24300027
132Purine metabolism_Homo sapiens_hsa002300.24246208
133Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.24123083
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.23110959
135AMPK signaling pathway_Homo sapiens_hsa041520.22828903
136Renal cell carcinoma_Homo sapiens_hsa052110.21334275
137Ras signaling pathway_Homo sapiens_hsa040140.20661230

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