FAM129C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)9.71501377
2B cell receptor signaling pathway (GO:0050853)9.49130118
3positive regulation of B cell differentiation (GO:0045579)8.29909314
4regulation of gamma-delta T cell differentiation (GO:0045586)7.40669660
5serine transport (GO:0032329)7.29434122
6L-serine transport (GO:0015825)7.00990310
7regulation of gamma-delta T cell activation (GO:0046643)6.79670074
8V(D)J recombination (GO:0033151)6.39953092
9regulation of B cell differentiation (GO:0045577)6.34972509
10regulation of superoxide anion generation (GO:0032928)6.30759725
11neutrophil activation involved in immune response (GO:0002283)5.90838215
12regulation of histone H3-K9 methylation (GO:0051570)5.64696910
13neutrophil activation (GO:0042119)5.52375731
14positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)5.44527639
15positive regulation of mast cell degranulation (GO:0043306)5.40434662
16positive regulation of mast cell activation involved in immune response (GO:0033008)5.40434662
17regulation of platelet aggregation (GO:0090330)5.29162177
18lymph vessel development (GO:0001945)5.25972020
19granulocyte activation (GO:0036230)4.89047439
20regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)4.72751969
21negative regulation of histone methylation (GO:0031061)4.68925794
22macrophage activation involved in immune response (GO:0002281)4.66938033
23positive regulation of cell adhesion mediated by integrin (GO:0033630)4.61524344
24B cell proliferation (GO:0042100)4.47897275
25hepatocyte apoptotic process (GO:0097284)4.44245630
26regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.38668007
27positive regulation of mast cell activation (GO:0033005)4.38141797
28antibacterial humoral response (GO:0019731)4.31752751
29natural killer cell differentiation (GO:0001779)4.31336093
30negative regulation of phagocytosis (GO:0050765)4.29149843
31regulation of B cell receptor signaling pathway (GO:0050855)4.27302763
32positive regulation of myeloid leukocyte mediated immunity (GO:0002888)4.24341492
33positive regulation of bone remodeling (GO:0046852)4.18474399
34positive regulation of bone resorption (GO:0045780)4.18474399
35antimicrobial humoral response (GO:0019730)4.15199561
36mucosal-associated lymphoid tissue development (GO:0048537)4.12607208
37Peyers patch development (GO:0048541)4.12607208
38regulation of alpha-beta T cell proliferation (GO:0046640)4.09569858
39regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.06991020
40vesicle targeting (GO:0006903)4.06871848
41cellular response to zinc ion (GO:0071294)4.03076828
42germ cell migration (GO:0008354)3.98845267
43antigen processing and presentation of endogenous antigen (GO:0019883)3.91977055
44positive regulation of leukocyte degranulation (GO:0043302)3.91856802
45T cell homeostasis (GO:0043029)3.87660046
46antigen receptor-mediated signaling pathway (GO:0050851)3.82332032
47regulation of antigen processing and presentation (GO:0002577)3.82217706
48regulation of superoxide metabolic process (GO:0090322)3.80499475
49negative thymic T cell selection (GO:0045060)3.74111564
50immunoglobulin mediated immune response (GO:0016064)3.73454423
51negative regulation of bone resorption (GO:0045779)3.73260156
52negative T cell selection (GO:0043383)3.69298127
53positive T cell selection (GO:0043368)3.68373750
54DNA deamination (GO:0045006)3.68188832
55regulation of germinal center formation (GO:0002634)3.62926034
56positive regulation of alpha-beta T cell proliferation (GO:0046641)3.61767533
57cellular hyperosmotic response (GO:0071474)3.60691187
58positive regulation by host of viral transcription (GO:0043923)3.59724172
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.59242022
60fucose catabolic process (GO:0019317)3.55477232
61L-fucose metabolic process (GO:0042354)3.55477232
62L-fucose catabolic process (GO:0042355)3.55477232
63regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.54218609
64regulation of mast cell degranulation (GO:0043304)3.52025944
65lymphocyte homeostasis (GO:0002260)3.51696210
66antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.47553300
67antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.47553300
68negative regulation of B cell proliferation (GO:0030889)3.46105452
69regulation of dendritic cell antigen processing and presentation (GO:0002604)3.45067893
70somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.44321874
71somatic cell DNA recombination (GO:0016444)3.44321874
72tachykinin receptor signaling pathway (GO:0007217)3.41238457
73positive regulation of antigen processing and presentation (GO:0002579)3.40949603
74T cell selection (GO:0045058)3.40816242
75regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.40329201
76protein-DNA complex disassembly (GO:0032986)3.40007321
77nucleosome disassembly (GO:0006337)3.40007321
78positive regulation of granulocyte differentiation (GO:0030854)3.37885634
79regulation of MHC class I biosynthetic process (GO:0045343)3.37498811
80activated T cell proliferation (GO:0050798)3.33457944
81response to protozoan (GO:0001562)3.32604282
82regulation of icosanoid secretion (GO:0032303)3.32054922
83adaptation of signaling pathway (GO:0023058)3.29373612
84regulation of interferon-beta biosynthetic process (GO:0045357)3.29260603
85positive regulation of gene expression, epigenetic (GO:0045815)3.28050133
86regulation of B cell proliferation (GO:0030888)3.26798951
87negative regulation of calcium ion transport into cytosol (GO:0010523)3.24544016
88positive regulation of protein homooligomerization (GO:0032464)3.24134746
89negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.23241307
90negative regulation of T-helper cell differentiation (GO:0045623)3.23241307
91negative regulation of cell killing (GO:0031342)3.22840055
92negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.22840055
93positive regulation of B cell activation (GO:0050871)3.22415868
94B cell differentiation (GO:0030183)3.20387316
95cellular response to exogenous dsRNA (GO:0071360)3.20075580
96myelin maintenance (GO:0043217)3.19728391
97positive regulation of defense response to virus by host (GO:0002230)3.19458952
98regulation of mast cell activation involved in immune response (GO:0033006)3.18040215
99cellular response to interleukin-15 (GO:0071350)3.16935538
100regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.16414434
101immune response-activating cell surface receptor signaling pathway (GO:0002429)3.16282191
102negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.13945420
103somatic diversification of immune receptors (GO:0002200)3.13150873
104B cell activation (GO:0042113)3.12323718
105regulation of homotypic cell-cell adhesion (GO:0034110)3.11547169
106tolerance induction (GO:0002507)3.10348200
107Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)3.10230752
108immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00023.10230752
109Fc-gamma receptor signaling pathway (GO:0038094)3.10230752
110response to interleukin-15 (GO:0070672)3.07238536
111activation of JUN kinase activity (GO:0007257)3.07137782
112leukotriene biosynthetic process (GO:0019370)3.07014975
113Fc receptor mediated stimulatory signaling pathway (GO:0002431)3.05510131
114mitotic chromosome condensation (GO:0007076)3.03882640
115B cell homeostasis (GO:0001782)3.03876814
116leukocyte homeostasis (GO:0001776)3.03809751
117regulation of B cell apoptotic process (GO:0002902)3.01848692
118negative regulation of lymphocyte mediated immunity (GO:0002707)3.00913299
119negative regulation of mast cell activation (GO:0033004)3.00678420
120mature B cell differentiation (GO:0002335)3.00553609
121purinergic nucleotide receptor signaling pathway (GO:0035590)3.00540572
122antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.97057578
123positive regulation of alpha-beta T cell differentiation (GO:0046638)2.95625659
124DNA topological change (GO:0006265)2.94880095
125thymic T cell selection (GO:0045061)2.94578633
126negative regulation of bone remodeling (GO:0046851)2.94236912
127defense response to protozoan (GO:0042832)2.91860970
128mononuclear cell proliferation (GO:0032943)2.91821318
129detection of bacterium (GO:0016045)2.91216994
130production of molecular mediator involved in inflammatory response (GO:0002532)2.90848086
131leukocyte aggregation (GO:0070486)2.90536128
132positive thymic T cell selection (GO:0045059)2.89781620
133lymphocyte proliferation (GO:0046651)2.89469536
134mast cell activation (GO:0045576)2.86848406
135interferon-gamma-mediated signaling pathway (GO:0060333)2.86663146
136positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.86646022
137regulation of histone methylation (GO:0031060)2.86057029
138regulation of bone resorption (GO:0045124)2.85179288
139regulation of T cell mediated cytotoxicity (GO:0001914)2.85004256
140B cell mediated immunity (GO:0019724)2.84034261
141negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.83981053
142interferon-gamma production (GO:0032609)2.82722552
143regulation of mast cell activation (GO:0033003)2.81621024
144positive regulation of interferon-alpha production (GO:0032727)2.80840670
145positive regulation of T cell mediated cytotoxicity (GO:0001916)2.80199766
146negative regulation of T cell mediated immunity (GO:0002710)2.78167761
147positive regulation of B cell proliferation (GO:0030890)2.77378761
148detection of other organism (GO:0098543)2.76890009
149pyrimidine ribonucleoside catabolic process (GO:0046133)2.75887259
150negative regulation of alpha-beta T cell activation (GO:0046636)2.75645859
151CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.73935540
152mast cell degranulation (GO:0043303)2.72834277
153mast cell activation involved in immune response (GO:0002279)2.72834277
154modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.69608997
155positive regulation by organism of defense response of other organism involved in symbiotic interact2.69608997
156modulation by symbiont of host immune response (GO:0052553)2.69608997
157positive regulation by symbiont of host defense response (GO:0052509)2.69608997
158modulation by symbiont of host defense response (GO:0052031)2.69608997
159modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.69608997
160regulation of interferon-alpha production (GO:0032647)2.69271660
161response to type I interferon (GO:0034340)2.69041104
162cytidine metabolic process (GO:0046087)2.65012480
163cytidine catabolic process (GO:0006216)2.65012480
164cytidine deamination (GO:0009972)2.65012480
165regulation of T cell receptor signaling pathway (GO:0050856)2.62804118
166positive regulation of CREB transcription factor activity (GO:0032793)2.61439828
167negative regulation of adaptive immune response (GO:0002820)2.60968359
168type I interferon signaling pathway (GO:0060337)2.59603633
169cellular response to type I interferon (GO:0071357)2.59603633
170regulation of defense response to virus by host (GO:0050691)2.58840158
171indolalkylamine metabolic process (GO:0006586)2.58247850

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.57599614
2MYC_22102868_ChIP-Seq_BL_Human4.83593145
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.79649219
4SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.94869026
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.87683638
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.71419388
7VDR_21846776_ChIP-Seq_THP-1_Human3.68383857
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.42624433
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.29838566
10ZNF274_21170338_ChIP-Seq_K562_Hela2.83597033
11* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.79102893
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.64811179
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.61667335
14EZH2_22144423_ChIP-Seq_EOC_Human2.56169568
15RUNX_20019798_ChIP-Seq_JUKART_Human2.50813526
16E2F4_17652178_ChIP-ChIP_JURKAT_Human2.44275521
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.34319719
18MAF_26560356_Chip-Seq_TH1_Human2.31524010
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.24129084
20IRF8_27001747_Chip-Seq_BMDM_Mouse2.20707838
21FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.15072745
22* UTX_26944678_Chip-Seq_JUKART_Human2.13702213
23MYB_26560356_Chip-Seq_TH2_Human2.10417070
24TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.10253300
25VDR_24763502_ChIP-Seq_THP-1_Human2.07700517
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.06195867
27TCF7_22412390_ChIP-Seq_EML_Mouse2.01239367
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse10.4684968
29MYB_26560356_Chip-Seq_TH1_Human1.98941522
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.96239688
31GATA3_26560356_Chip-Seq_TH2_Human1.92573763
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.89780175
33* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.87163761
34SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.83315131
35SCL_19346495_ChIP-Seq_HPC-7_Human1.81877342
36BRD4_27068464_Chip-Seq_AML-cells_Mouse1.81254717
37CIITA_25753668_ChIP-Seq_RAJI_Human1.78853397
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.77703283
39VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.75068313
40LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.73278605
41FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.64693323
42STAT4_19710469_ChIP-ChIP_TH1__Mouse1.64338341
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62022479
44IGF1R_20145208_ChIP-Seq_DFB_Human1.61567042
45* KDM2B_26808549_Chip-Seq_DND41_Human1.61232509
46GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59471030
47VDR_22108803_ChIP-Seq_LS180_Human1.58451009
48NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.56506219
49TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.54447564
50VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.48720370
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.45390431
52NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.45214281
53* SPI1_23547873_ChIP-Seq_NB4_Human1.42751350
54SPI1_23127762_ChIP-Seq_K562_Human1.42062560
55STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40451830
56FLI1_27457419_Chip-Seq_LIVER_Mouse1.40433514
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.39545596
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36621593
59GATA1_22025678_ChIP-Seq_K562_Human1.36010657
60ER_23166858_ChIP-Seq_MCF-7_Human1.35119004
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.33607261
62NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.31410578
63MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30444984
64EGR1_23403033_ChIP-Seq_LIVER_Mouse1.30045076
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28492092
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28340087
67KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.28004424
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26781742
69GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26197280
70BCAT_22108803_ChIP-Seq_LS180_Human1.26040045
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.25344316
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24721462
73TP53_22573176_ChIP-Seq_HFKS_Human1.22112473
74GATA3_27048872_Chip-Seq_THYMUS_Human1.20699559
75IKZF1_21737484_ChIP-ChIP_HCT116_Human1.19798386
76GATA1_22383799_ChIP-Seq_G1ME_Mouse1.19022644
77MAF_26560356_Chip-Seq_TH2_Human1.18548410
78SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.17784940
79STAT6_21828071_ChIP-Seq_BEAS2B_Human1.16434262
80ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16418564
81PRDM14_20953172_ChIP-Seq_ESCs_Human1.15079338
82RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14431727
83DROSHA_22980978_ChIP-Seq_HELA_Human1.13256190
84GATA3_26560356_Chip-Seq_TH1_Human1.13035418
85ZFP57_27257070_Chip-Seq_ESCs_Mouse1.12158523
86GATA3_21878914_ChIP-Seq_MCF-7_Human1.11993472
87FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.11815326
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.11756303
89TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11470742
90RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.10548696
91MYB_21317192_ChIP-Seq_ERMYB_Mouse1.10061585
92CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10044906
93EWS_26573619_Chip-Seq_HEK293_Human1.09128283
94ELK3_25401928_ChIP-Seq_HUVEC_Human1.08921638
95IRF1_19129219_ChIP-ChIP_H3396_Human1.08149753
96GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07476523
97POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05318739
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05318739
99MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02528093
100ETV2_25802403_ChIP-Seq_MESCs_Mouse1.01904303
101TAF15_26573619_Chip-Seq_HEK293_Human1.01851719
102TP63_19390658_ChIP-ChIP_HaCaT_Human1.01238733
103SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.00941950
104PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00514031
105PU.1_20513432_ChIP-Seq_Bcells_Mouse0.99893707
106POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99317269
107FOXA1_25329375_ChIP-Seq_VCAP_Human0.99230958
108FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99230958
109ERA_21632823_ChIP-Seq_H3396_Human0.98441876
110RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.98388578
111CTBP2_25329375_ChIP-Seq_LNCAP_Human0.98303863
112HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.98293670
113RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97496300
114NANOG_20526341_ChIP-Seq_ESCs_Human0.97480821
115PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97176163
116SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96694817
117TCF4_23295773_ChIP-Seq_U87_Human0.96168162
118ETS1_22383799_ChIP-Seq_G1ME_Mouse0.96048493
119TAF2_19829295_ChIP-Seq_ESCs_Human0.94825600
120GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.94223694
121PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93859710
122EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.93085134
123GBX2_23144817_ChIP-Seq_PC3_Human0.92950893
124* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92850621
125PU_27001747_Chip-Seq_BMDM_Mouse0.91362238
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89933240
127BP1_19119308_ChIP-ChIP_Hs578T_Human0.89876533
128STAT3_23295773_ChIP-Seq_U87_Human0.89793182
129RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.89638040
130KDM2B_26808549_Chip-Seq_JURKAT_Human0.88954129
131NCOR1_26117541_ChIP-Seq_K562_Human0.84838476
132VDR_23849224_ChIP-Seq_CD4+_Human0.82319739
133VDR_24787735_ChIP-Seq_THP-1_Human0.79654036
134POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78496157
135FOXP3_21729870_ChIP-Seq_TREG_Human0.77660968
136RBPJ_22232070_ChIP-Seq_NCS_Mouse0.75754180
137EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.74729016
138CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.73496479
139LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.73118589
140GATA1_19941826_ChIP-Seq_K562_Human0.72791362
141MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.71981931
142IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.70781978
143KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.68973500
144GATA1_19941827_ChIP-Seq_MEL_Mouse0.68502900
145P300_27268052_Chip-Seq_Bcells_Human0.68438055
146* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.67729679
147SMRT_27268052_Chip-Seq_Bcells_Human0.67139683
148CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.64648145
149CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.63867386
150FOXO3_23340844_ChIP-Seq_DLD1_Human0.63851883
151BCL6_27268052_Chip-Seq_Bcells_Human0.63292693
152CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.62173608
153PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.61135437

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001800_abnormal_humoral_immune4.63571739
2MP0001835_abnormal_antigen_presentation4.26587914
3MP0006054_spinal_hemorrhage4.07631966
4MP0001790_abnormal_immune_system3.96197521
5MP0005387_immune_system_phenotype3.96197521
6MP0000685_abnormal_immune_system3.87735801
7MP0003303_peritoneal_inflammation3.68264525
8MP0002452_abnormal_antigen_presenting3.54030933
9MP0002166_altered_tumor_susceptibility3.19921582
10MP0002398_abnormal_bone_marrow3.06920549
11MP0002420_abnormal_adaptive_immunity2.85231054
12MP0002723_abnormal_immune_serum2.84365395
13MP0001819_abnormal_immune_cell2.78165784
14MP0000689_abnormal_spleen_morphology2.76232315
15MP0005000_abnormal_immune_tolerance2.74962715
16MP0002396_abnormal_hematopoietic_system2.72531710
17MP0000716_abnormal_immune_system2.67119703
18MP0005671_abnormal_response_to2.59701576
19MP0002722_abnormal_immune_system2.42122957
20MP0003724_increased_susceptibility_to2.41439765
21MP0004808_abnormal_hematopoietic_stem2.26362302
22MP0002006_tumorigenesis2.21944025
23MP0002429_abnormal_blood_cell2.20595605
24MP0000703_abnormal_thymus_morphology2.20127719
25MP0003436_decreased_susceptibility_to2.19331668
26MP0005075_abnormal_melanosome_morpholog2.18323377
27MP0001879_abnormal_lymphatic_vessel2.17015226
28MP0001986_abnormal_taste_sensitivity2.14460025
29MP0003300_gastrointestinal_ulcer2.08462428
30MP0003646_muscle_fatigue2.08363200
31MP0009785_altered_susceptibility_to1.80042670
32MP0005025_abnormal_response_to1.79806952
33MP0003763_abnormal_thymus_physiology1.76174284
34MP0010234_abnormal_vibrissa_follicle1.74974676
35MP0000465_gastrointestinal_hemorrhage1.65876940
36MP0010155_abnormal_intestine_physiology1.63797209
37MP0010094_abnormal_chromosome_stability1.60456446
38MP0004043_abnormal_pH_regulation1.56939821
39MP0008057_abnormal_DNA_replication1.53219860
40MP0005645_abnormal_hypothalamus_physiol1.52532290
41MP0002019_abnormal_tumor_incidence1.51183093
42MP0010352_gastrointestinal_tract_polyps1.49464762
43MP0004947_skin_inflammation1.48339661
44MP0002405_respiratory_system_inflammati1.47649303
45MP0002419_abnormal_innate_immunity1.47055791
46MP0009278_abnormal_bone_marrow1.44852533
47MP0002653_abnormal_ependyma_morphology1.41996348
48MP0003172_abnormal_lysosome_physiology1.38360913
49MP0003787_abnormal_imprinting1.38072780
50MP0002933_joint_inflammation1.37875092
51MP0009764_decreased_sensitivity_to1.37640562
52MP0001845_abnormal_inflammatory_respons1.36345019
53MP0003195_calcinosis1.35528202
54MP0004381_abnormal_hair_follicle1.30939150
55MP0003866_abnormal_defecation1.26515708
56MP0001873_stomach_inflammation1.26299169
57MP0003252_abnormal_bile_duct1.24395927
58MP0003077_abnormal_cell_cycle1.22724957
59MP0002148_abnormal_hypersensitivity_rea1.22145229
60MP0008872_abnormal_physiological_respon1.21772154
61MP0003183_abnormal_peptide_metabolism1.12460146
62MP0005551_abnormal_eye_electrophysiolog1.08976760
63MP0000372_irregular_coat_pigmentation1.06990879
64MP0006082_CNS_inflammation1.04964576
65MP0004142_abnormal_muscle_tone1.03937824
66MP0001968_abnormal_touch/_nociception1.03164927
67MP0005076_abnormal_cell_differentiation0.99205412
68MP0001501_abnormal_sleep_pattern0.98739049
69MP0002095_abnormal_skin_pigmentation0.98666802
70MP0000490_abnormal_crypts_of0.97909698
71MP0002009_preneoplasia0.97141823
72MP0002693_abnormal_pancreas_physiology0.94684583
73MP0002132_abnormal_respiratory_system0.94307728
74MP0005464_abnormal_platelet_physiology0.93925185
75MP0003111_abnormal_nucleus_morphology0.93491559
76MP0008961_abnormal_basal_metabolism0.93333839
77MP0001853_heart_inflammation0.91843027
78MP0005397_hematopoietic_system_phenotyp0.91516164
79MP0001545_abnormal_hematopoietic_system0.91516164
80MP0000350_abnormal_cell_proliferation0.91237239
81MP0002136_abnormal_kidney_physiology0.90493883
82MP0004510_myositis0.85765137
83MP0003091_abnormal_cell_migration0.84470943
84MP0000569_abnormal_digit_pigmentation0.83708157
85MP0005084_abnormal_gallbladder_morpholo0.83457660
86MP0002102_abnormal_ear_morphology0.80966075
87MP0002876_abnormal_thyroid_physiology0.80405050
88MP0005310_abnormal_salivary_gland0.79901132
89MP0003045_fibrosis0.79007982
90MP0001915_intracranial_hemorrhage0.77129132
91MP0003453_abnormal_keratinocyte_physiol0.77031315
92MP0003279_aneurysm0.76061789
93MP0003693_abnormal_embryo_hatching0.74891979
94MP0001764_abnormal_homeostasis0.70713549
95MP0002928_abnormal_bile_duct0.70335376
96MP0005501_abnormal_skin_physiology0.69329539
97MP0009931_abnormal_skin_appearance0.68682484
98MP0005621_abnormal_cell_physiology0.68661712
99MP0005253_abnormal_eye_physiology0.68087662
100MP0004883_abnormal_blood_vessel0.67696034
101MP0003566_abnormal_cell_adhesion0.67554628
102MP0008877_abnormal_DNA_methylation0.67190832
103MP0009333_abnormal_splenocyte_physiolog0.66538077
104MP0009745_abnormal_behavioral_response0.66302160
105MP0000470_abnormal_stomach_morphology0.66215818
106MP0010307_abnormal_tumor_latency0.65341130
107MP0002163_abnormal_gland_morphology0.65245927
108MP0000313_abnormal_cell_death0.64856600
109MP0008469_abnormal_protein_level0.64689935
110MP0004885_abnormal_endolymph0.64360657
111MP0000371_diluted_coat_color0.63187181
112MP0008874_decreased_physiological_sensi0.62255387
113MP0000427_abnormal_hair_cycle0.62110665
114MP0001784_abnormal_fluid_regulation0.62010740
115MP0001533_abnormal_skeleton_physiology0.61587705
116MP0001919_abnormal_reproductive_system0.61335154
117MP0004130_abnormal_muscle_cell0.60928042
118MP0003656_abnormal_erythrocyte_physiolo0.60767518
119MP0002083_premature_death0.60530159
120MP0004742_abnormal_vestibular_system0.60520039
121MP0001730_embryonic_growth_arrest0.60496486
122MP0000733_abnormal_muscle_development0.59383489
123MP0004957_abnormal_blastocyst_morpholog0.58911349
124MP0001663_abnormal_digestive_system0.58832944
125MP0008007_abnormal_cellular_replicative0.58048607
126MP0002138_abnormal_hepatobiliary_system0.57741739
127MP0000249_abnormal_blood_vessel0.57302545
128MP0008995_early_reproductive_senescence0.56481683
129MP0004197_abnormal_fetal_growth/weight/0.55499227
130MP0005389_reproductive_system_phenotype0.55116805
131MP0005167_abnormal_blood-brain_barrier0.54241274
132MP0002277_abnormal_respiratory_mucosa0.54217517
133MP0002638_abnormal_pupillary_reflex0.53199315
134MP0004484_altered_response_of0.53109447
135MP0010329_abnormal_lipoprotein_level0.52956211
136MP0004147_increased_porphyrin_level0.52801983
137MP0002060_abnormal_skin_morphology0.52661090
138MP0001849_ear_inflammation0.52263367
139MP0000015_abnormal_ear_pigmentation0.51630949
140MP0000767_abnormal_smooth_muscle0.50801245
141MP0005174_abnormal_tail_pigmentation0.50537828
142MP0003943_abnormal_hepatobiliary_system0.47907728
143MP0005384_cellular_phenotype0.47482464

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)8.99398580
2Verrucae (HP:0200043)7.58947340
3Papilloma (HP:0012740)7.58947340
4B lymphocytopenia (HP:0010976)7.21828118
5Abnormality of B cell number (HP:0010975)7.21828118
6Cellulitis (HP:0100658)7.01136057
7Small epiphyses (HP:0010585)6.10980033
8Thyroiditis (HP:0100646)5.95671887
9Recurrent bronchitis (HP:0002837)5.47213322
10Gastrointestinal stroma tumor (HP:0100723)5.40214928
11Colitis (HP:0002583)5.23661096
12Recurrent viral infections (HP:0004429)5.21383690
13Panhypogammaglobulinemia (HP:0003139)5.20271321
14Recurrent sinusitis (HP:0011108)4.77747300
15Meningitis (HP:0001287)4.68764618
16Vertebral arch anomaly (HP:0008438)4.50335727
17Inflammation of the large intestine (HP:0002037)4.35304301
18Chronic sinusitis (HP:0011109)4.24165583
19Osteomyelitis (HP:0002754)4.24114463
20Gastrointestinal inflammation (HP:0004386)4.24066456
21Mitral stenosis (HP:0001718)4.14224526
22Sepsis (HP:0100806)4.02849391
23Hypoplasia of the thymus (HP:0000778)3.96965467
24Severe combined immunodeficiency (HP:0004430)3.96941729
25Abnormality of the intervertebral disk (HP:0005108)3.90873939
26Flattened epiphyses (HP:0003071)3.79544023
27Hypoplasia of the capital femoral epiphysis (HP:0003090)3.79490045
28Recurrent pneumonia (HP:0006532)3.70079431
29Combined immunodeficiency (HP:0005387)3.61490204
30Lymphopenia (HP:0001888)3.54764053
31Recurrent fungal infections (HP:0002841)3.48141224
32Ulnar bowing (HP:0003031)3.41428058
33T lymphocytopenia (HP:0005403)3.40201511
34IgM deficiency (HP:0002850)3.40096026
35Stomatitis (HP:0010280)3.39188426
36Abnormality of cells of the lymphoid lineage (HP:0012140)3.38079670
37Recurrent otitis media (HP:0000403)3.37886123
38IgG deficiency (HP:0004315)3.28829615
39Congenital stationary night blindness (HP:0007642)3.23865891
40Abnormality of T cell number (HP:0011839)3.15382453
41Arthropathy (HP:0003040)3.14196467
42Emphysema (HP:0002097)3.11458107
43Recurrent lower respiratory tract infections (HP:0002783)3.10549940
44Encephalitis (HP:0002383)3.09159643
45Bronchitis (HP:0012387)3.07143618
46Pancreatic cysts (HP:0001737)3.00889339
47Absent epiphyses (HP:0010577)3.00792219
48Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.00792219
49Elevated erythrocyte sedimentation rate (HP:0003565)2.93517197
50Eczematoid dermatitis (HP:0000976)2.89068562
51Irregular vertebral endplates (HP:0003301)2.85278830
52Stomach cancer (HP:0012126)2.83603484
53Eosinophilia (HP:0001880)2.79653499
54Retrobulbar optic neuritis (HP:0100654)2.78443537
55Optic neuritis (HP:0100653)2.78443537
56Myositis (HP:0100614)2.75887067
57Abnormality of T cell physiology (HP:0011840)2.75211683
58Restrictive lung disease (HP:0002091)2.70020499
59Abnormal delayed hypersensitivity skin test (HP:0002963)2.66936644
60Vasculitis (HP:0002633)2.66085053
61Clumsiness (HP:0002312)2.61914046
62Attenuation of retinal blood vessels (HP:0007843)2.59593156
63Abnormality of the fingertips (HP:0001211)2.56817872
64Skin rash (HP:0000988)2.54951417
65Abnormality of the prostate (HP:0008775)2.53524933
66Hypoproteinemia (HP:0003075)2.46866392
67Orchitis (HP:0100796)2.46098352
68Pustule (HP:0200039)2.42827344
69Barrel-shaped chest (HP:0001552)2.41752913
70Abnormality of midbrain morphology (HP:0002418)2.41461183
71Molar tooth sign on MRI (HP:0002419)2.41461183
72Chronic otitis media (HP:0000389)2.40379521
73Vertebral clefting (HP:0008428)2.37099322
74Abnormality of T cells (HP:0002843)2.35934182
75Lymphoma (HP:0002665)2.35032974
76Abnormality of eosinophils (HP:0001879)2.32979612
77Limited elbow extension (HP:0001377)2.32743012
78Granulocytopenia (HP:0001913)2.31980795
79Gastrointestinal infarctions (HP:0005244)2.30866876
80Hyperventilation (HP:0002883)2.26568629
81Abnormality of the renal cortex (HP:0011035)2.21541664
82Chronic obstructive pulmonary disease (HP:0006510)2.18729923
83Obstructive lung disease (HP:0006536)2.18729923
84Autoimmune thrombocytopenia (HP:0001973)2.18134006
85Neutropenia (HP:0001875)2.18038409
86Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.17658234
87Pancreatic fibrosis (HP:0100732)2.17038980
88Pulmonary infiltrates (HP:0002113)2.15960252
89Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15485658
90Recurrent gram-negative bacterial infections (HP:0005420)2.14642604
91Abnormal biliary tract physiology (HP:0012439)2.13206799
92Bile duct proliferation (HP:0001408)2.13206799
93Abnormal rod and cone electroretinograms (HP:0008323)2.12634183
94Abnormality of the vertebral endplates (HP:0005106)2.11670285
95Aqueductal stenosis (HP:0002410)2.10952017
96Abolished electroretinogram (ERG) (HP:0000550)2.09207293
97Recurrent cutaneous fungal infections (HP:0011370)2.06870463
98Chronic mucocutaneous candidiasis (HP:0002728)2.06870463
99Hypochromic anemia (HP:0001931)2.05730231
100Keratoconjunctivitis (HP:0001096)2.05386602
101Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.04944100
102Hemoptysis (HP:0002105)2.04940762
103Chronic hepatic failure (HP:0100626)2.03861164
104Recurrent bacterial skin infections (HP:0005406)2.03783875
105Genetic anticipation (HP:0003743)2.03077034
106Protruding tongue (HP:0010808)2.02303387
107Mediastinal lymphadenopathy (HP:0100721)2.01954561
108Nephronophthisis (HP:0000090)1.99984088
109Recurrent abscess formation (HP:0002722)1.98195790
110Aortic regurgitation (HP:0001659)1.96857479
111Bowing of the arm (HP:0006488)1.96848723
112Bowed forearm bones (HP:0003956)1.96848723
113Gaze-evoked nystagmus (HP:0000640)1.95109855
114Prostate neoplasm (HP:0100787)1.94700211
115Facial diplegia (HP:0001349)1.93569969
116Skin ulcer (HP:0200042)1.93242704
117Abnormality of the pleura (HP:0002103)1.93129432
118Leukopenia (HP:0001882)1.92258361
119Hypochromic microcytic anemia (HP:0004840)1.91298432
120True hermaphroditism (HP:0010459)1.91023425
121IgA deficiency (HP:0002720)1.90720709
122Abnormality of macrophages (HP:0004311)1.90274242
123Volvulus (HP:0002580)1.90134132
124Abnormal drinking behavior (HP:0030082)1.89554571
125Polydipsia (HP:0001959)1.89554571
126Viral hepatitis (HP:0006562)1.88019266
127Dehydration (HP:0001944)1.87818797
128Cutis marmorata (HP:0000965)1.87707524
129Long eyelashes (HP:0000527)1.86529488
130Hematochezia (HP:0002573)1.85909772
131Keratoconjunctivitis sicca (HP:0001097)1.85907270
132Abnormality of the renal medulla (HP:0100957)1.85689114
133Prolonged bleeding time (HP:0003010)1.84673657
134Aplasia/Hypoplasia of the thymus (HP:0010515)1.83864781
135Abnormality of carpal bone ossification (HP:0006257)1.82554838
136Abnormality of the tricuspid valve (HP:0001702)1.82494738
137Abnormality of the thymus (HP:0000777)1.78638494
138Acute lymphatic leukemia (HP:0006721)1.78576576
139Cutaneous melanoma (HP:0012056)1.78027475
140Cortical dysplasia (HP:0002539)1.75607973
141Leukocytosis (HP:0001974)1.72965683
142Recurrent skin infections (HP:0001581)1.72241785
143Abnormal ossification of hand bones (HP:0005921)1.71692316
144Cubitus valgus (HP:0002967)1.70500673
145Spontaneous hematomas (HP:0007420)1.66135052
146External ear malformation (HP:0008572)1.65862815
147Asymmetry of the thorax (HP:0001555)1.63713726
148Short femoral neck (HP:0100864)1.62372234
149Erythroderma (HP:0001019)1.62223040
150Abnormal hand bone ossification (HP:0010660)1.61231505
151Increased IgE level (HP:0003212)1.58234194

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K109.14962626
2GRK64.87366540
3TLK13.68744918
4MAP4K13.25881856
5ERN12.83055779
6TXK2.69297412
7STK42.51188710
8TAOK32.41170015
9RIPK42.24996795
10SYK2.20557009
11ADRBK22.14117134
12IRAK42.10031915
13ACVR1B2.09755110
14BLK1.96741479
15IKBKE1.84610622
16CSF1R1.82880798
17BTK1.82193240
18EEF2K1.77564926
19SIK21.74391920
20DYRK1B1.71034225
21CDK91.64854045
22BMPR1B1.62859575
23PIM11.53878334
24KIT1.53758847
25STK101.53014338
26FRK1.52598363
27ZAK1.50969606
28LRRK21.45424066
29LYN1.41844249
30BMPR21.39964970
31CDK121.35941602
32CDK41.34022874
33MAP4K21.29675945
34JAK31.27792580
35WNK41.27672233
36NUAK11.26209399
37TRIB31.24468456
38EIF2AK31.23685714
39DYRK31.21460659
40NEK21.20704120
41MAPK131.19850255
42MAPK71.14618580
43FES1.13836521
44MAP3K141.13351595
45FGFR21.12466027
46MAP2K11.09174156
47CSK1.06405739
48WNK11.05298954
49HCK1.05152011
50TYK21.02556231
51MAP3K81.00244586
52INSRR0.94367686
53CLK10.91686419
54RPS6KB20.90750091
55MAPK40.89651024
56RPS6KA50.88629018
57FGFR30.87831307
58PINK10.87801681
59TNK20.85773964
60PKN10.84095775
61OXSR10.83129852
62MATK0.82600168
63MARK30.80688478
64LCK0.79674602
65HIPK20.79393124
66PIK3CG0.78554228
67JAK10.77899975
68PRKD10.77678942
69ADRBK10.77567681
70IRAK10.76588085
71VRK10.75418154
72SIK10.73044844
73WNK30.72927744
74PKN20.70935699
75TBK10.68294058
76DAPK20.66637089
77MAP3K70.65910700
78PTK2B0.60550435
79MAP2K60.58897043
80MAP3K130.58381403
81CSNK1D0.58227201
82CAMKK20.57091416
83MAP3K110.56143477
84TESK20.55949729
85MELK0.55062893
86PRKCQ0.54359933
87MST40.54203386
88CDK30.53850024
89ITK0.52852992
90CDC42BPA0.52186405
91STK390.51663982
92FYN0.51327034
93PDK10.50936655
94ZAP700.50299008
95IKBKB0.50108438
96MAP2K20.49285296
97JAK20.48550697
98MAPK120.48288541
99FGR0.46126365
100AURKB0.46040218
101SCYL20.45687853
102TEC0.44728451
103BRD40.42790617
104CDK60.42339163
105RPS6KA60.42004420
106PRKD20.41047712
107SIK30.40552390
108TGFBR20.40239156
109MAPK110.40204850
110SGK20.39783067
111NLK0.39721173
112CHEK10.38820406
113CAMK10.37750207
114INSR0.37571577
115CAMKK10.36640141
116SGK30.36454261
117PRKAA10.34526164
118NTRK30.34013815
119CAMK40.31936248
120MAP3K40.30925604
121DYRK1A0.30550403
122PRKCZ0.28682944
123RPS6KB10.28575360
124PASK0.28195095
125STK110.27254812
126MUSK0.27218895
127EGFR0.27018187
128GRK10.26446515
129MARK20.26102402
130CHEK20.25297694
131STK160.25168132
132MAPK30.25149262
133PRKCH0.24364918
134MAP2K30.24087944
135CAMK1G0.24045852
136PRKAA20.23753257
137ABL10.23678293
138CDC70.22518717
139STK30.21758970
140RAF10.21073908
141ATR0.20461024
142PRKCD0.20227667
143ALK0.20154180
144CHUK0.19467359
145CAMK1D0.19326851
146PAK30.19206188

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046625.58978149
2Systemic lupus erythematosus_Homo sapiens_hsa053225.56607478
3Primary immunodeficiency_Homo sapiens_hsa053405.27136615
4Allograft rejection_Homo sapiens_hsa053303.58601448
5Asthma_Homo sapiens_hsa053103.54964403
6Graft-versus-host disease_Homo sapiens_hsa053323.54551027
7Autoimmune thyroid disease_Homo sapiens_hsa053203.46327751
8Non-homologous end-joining_Homo sapiens_hsa034503.45089649
9Alcoholism_Homo sapiens_hsa050343.31174167
10Type I diabetes mellitus_Homo sapiens_hsa049402.87204141
11Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.58092480
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.48633343
13Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.36685618
14Viral carcinogenesis_Homo sapiens_hsa052032.35996943
15Staphylococcus aureus infection_Homo sapiens_hsa051502.25304089
16Fc epsilon RI signaling pathway_Homo sapiens_hsa046642.14156216
17Intestinal immune network for IgA production_Homo sapiens_hsa046722.07249192
18Osteoclast differentiation_Homo sapiens_hsa043801.92406490
19Hematopoietic cell lineage_Homo sapiens_hsa046401.84274609
20Transcriptional misregulation in cancer_Homo sapiens_hsa052021.72270888
21Base excision repair_Homo sapiens_hsa034101.68444600
22Non-small cell lung cancer_Homo sapiens_hsa052231.64104080
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.56787768
24Linoleic acid metabolism_Homo sapiens_hsa005911.53228544
25Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.52547120
26Antigen processing and presentation_Homo sapiens_hsa046121.49382973
27Chronic myeloid leukemia_Homo sapiens_hsa052201.38757881
28Phototransduction_Homo sapiens_hsa047441.37833704
29Leishmaniasis_Homo sapiens_hsa051401.30079499
30Epstein-Barr virus infection_Homo sapiens_hsa051691.29162344
31Ether lipid metabolism_Homo sapiens_hsa005651.22700773
32T cell receptor signaling pathway_Homo sapiens_hsa046601.15448728
33Pancreatic cancer_Homo sapiens_hsa052121.15298883
34Chemokine signaling pathway_Homo sapiens_hsa040621.14923561
35Platelet activation_Homo sapiens_hsa046111.13769790
36Mismatch repair_Homo sapiens_hsa034301.10774782
37Rheumatoid arthritis_Homo sapiens_hsa053231.09631443
38Tuberculosis_Homo sapiens_hsa051521.07991591
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07432982
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07392796
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.07135565
42Glioma_Homo sapiens_hsa052141.04611221
43Measles_Homo sapiens_hsa051621.03598282
44Hepatitis B_Homo sapiens_hsa051611.02930453
45ABC transporters_Homo sapiens_hsa020101.00279743
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.98851537
47Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97647146
48Nitrogen metabolism_Homo sapiens_hsa009100.97086865
49Herpes simplex infection_Homo sapiens_hsa051680.96930312
50DNA replication_Homo sapiens_hsa030300.96792632
51MicroRNAs in cancer_Homo sapiens_hsa052060.93378581
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92448738
53Small cell lung cancer_Homo sapiens_hsa052220.92118742
54FoxO signaling pathway_Homo sapiens_hsa040680.90825036
55Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.90112890
56Caffeine metabolism_Homo sapiens_hsa002320.89113486
57HTLV-I infection_Homo sapiens_hsa051660.85304791
58Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84183895
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.83962698
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.83693957
61Acute myeloid leukemia_Homo sapiens_hsa052210.83374363
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.79475318
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.78548192
64Toxoplasmosis_Homo sapiens_hsa051450.77264197
65Regulation of autophagy_Homo sapiens_hsa041400.75154577
66Apoptosis_Homo sapiens_hsa042100.74616916
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.74059785
68Shigellosis_Homo sapiens_hsa051310.73778983
69Morphine addiction_Homo sapiens_hsa050320.73465108
70Fanconi anemia pathway_Homo sapiens_hsa034600.73299548
71SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73190164
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72501840
73RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71913135
74mTOR signaling pathway_Homo sapiens_hsa041500.70975211
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.67870095
76Prostate cancer_Homo sapiens_hsa052150.67339895
77Influenza A_Homo sapiens_hsa051640.65561330
78Arachidonic acid metabolism_Homo sapiens_hsa005900.64768371
79Inositol phosphate metabolism_Homo sapiens_hsa005620.64307798
80Cell cycle_Homo sapiens_hsa041100.63902537
81Lysine degradation_Homo sapiens_hsa003100.61222756
82VEGF signaling pathway_Homo sapiens_hsa043700.61151390
83Insulin resistance_Homo sapiens_hsa049310.61049883
84Colorectal cancer_Homo sapiens_hsa052100.60771012
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.59940063
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59270178
87Choline metabolism in cancer_Homo sapiens_hsa052310.59210766
88Taste transduction_Homo sapiens_hsa047420.58530121
89Butanoate metabolism_Homo sapiens_hsa006500.57582911
90Dorso-ventral axis formation_Homo sapiens_hsa043200.57184768
91mRNA surveillance pathway_Homo sapiens_hsa030150.55724529
92Spliceosome_Homo sapiens_hsa030400.55265121
93Pentose phosphate pathway_Homo sapiens_hsa000300.52740216
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.52499300
95Glycerolipid metabolism_Homo sapiens_hsa005610.52035844
96Type II diabetes mellitus_Homo sapiens_hsa049300.51575267
97Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49186474
98Selenocompound metabolism_Homo sapiens_hsa004500.49009948
99Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48729048
100Olfactory transduction_Homo sapiens_hsa047400.48088159
101Phagosome_Homo sapiens_hsa041450.48032890
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48026066
103Homologous recombination_Homo sapiens_hsa034400.46827616
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46291810
105Serotonergic synapse_Homo sapiens_hsa047260.44822978
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44620799
107MAPK signaling pathway_Homo sapiens_hsa040100.42708110
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42675417
109Hepatitis C_Homo sapiens_hsa051600.41732558
110Tryptophan metabolism_Homo sapiens_hsa003800.41336803
111Calcium signaling pathway_Homo sapiens_hsa040200.40634146
112p53 signaling pathway_Homo sapiens_hsa041150.40577379
113RNA polymerase_Homo sapiens_hsa030200.40502999
114TNF signaling pathway_Homo sapiens_hsa046680.38932135
115Endocytosis_Homo sapiens_hsa041440.37730648
116Ovarian steroidogenesis_Homo sapiens_hsa049130.37498668
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.35409884
118Endometrial cancer_Homo sapiens_hsa052130.34319938
119Nicotine addiction_Homo sapiens_hsa050330.34262432
120RNA degradation_Homo sapiens_hsa030180.33228200
121African trypanosomiasis_Homo sapiens_hsa051430.32131665
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.31549188
123Renal cell carcinoma_Homo sapiens_hsa052110.30999806
124Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.30824321
125ErbB signaling pathway_Homo sapiens_hsa040120.30703694
126Long-term depression_Homo sapiens_hsa047300.30693591
127Long-term potentiation_Homo sapiens_hsa047200.29703535
128Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28892738
129Proteoglycans in cancer_Homo sapiens_hsa052050.27954216
130Basal transcription factors_Homo sapiens_hsa030220.27731373
131Circadian entrainment_Homo sapiens_hsa047130.27436231
132Pertussis_Homo sapiens_hsa051330.27152571
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26785634
134Salmonella infection_Homo sapiens_hsa051320.25996855
135Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.25630207
136Pathways in cancer_Homo sapiens_hsa052000.25351360
137Cholinergic synapse_Homo sapiens_hsa047250.24828639
138Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.24379144
139Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.23923756
140Salivary secretion_Homo sapiens_hsa049700.22938828
141Regulation of actin cytoskeleton_Homo sapiens_hsa048100.21733404
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.21721736
143HIF-1 signaling pathway_Homo sapiens_hsa040660.21661191
144Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.21230528
145cGMP-PKG signaling pathway_Homo sapiens_hsa040220.21221437
146Glutamatergic synapse_Homo sapiens_hsa047240.21167965
147Ribosome_Homo sapiens_hsa030100.21163527
148Malaria_Homo sapiens_hsa051440.20462057
149Notch signaling pathway_Homo sapiens_hsa043300.18018401
150Glucagon signaling pathway_Homo sapiens_hsa049220.17158637
151Viral myocarditis_Homo sapiens_hsa054160.16384718

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