

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | erythrocyte maturation (GO:0043249) | 9.53712969 |
| 2 | granulocyte differentiation (GO:0030851) | 8.86115199 |
| 3 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 7.36752713 |
| 4 | histone H2B ubiquitination (GO:0033523) | 7.25522287 |
| 5 | response to nitrosative stress (GO:0051409) | 7.12848593 |
| 6 | response to misfolded protein (GO:0051788) | 7.12519197 |
| 7 | macrophage differentiation (GO:0030225) | 6.35942542 |
| 8 | estrogen biosynthetic process (GO:0006703) | 6.30285117 |
| 9 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 6.09504485 |
| 10 | protein destabilization (GO:0031648) | 5.96810259 |
| 11 | ribonucleoprotein complex disassembly (GO:0032988) | 5.91481845 |
| 12 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 5.90580593 |
| 13 | xenobiotic catabolic process (GO:0042178) | 5.89714605 |
| 14 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 5.56632078 |
| 15 | negative regulation of NF-kappaB import into nucleus (GO:0042347) | 5.36609298 |
| 16 | regulation of autophagic vacuole assembly (GO:2000785) | 5.01052145 |
| 17 | negative regulation of leukocyte migration (GO:0002686) | 4.94822821 |
| 18 | positive regulation of mRNA 3-end processing (GO:0031442) | 4.89716096 |
| 19 | cerebellar granule cell differentiation (GO:0021707) | 4.76063502 |
| 20 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.67136345 |
| 21 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 4.63393723 |
| 22 | cardiolipin metabolic process (GO:0032048) | 4.62448999 |
| 23 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 4.56551685 |
| 24 | cytoplasmic sequestering of transcription factor (GO:0042994) | 4.50529537 |
| 25 | regulation of mRNA 3-end processing (GO:0031440) | 4.47789725 |
| 26 | histone H2A acetylation (GO:0043968) | 4.45249600 |
| 27 | organelle disassembly (GO:1903008) | 4.38858385 |
| 28 | kinetochore organization (GO:0051383) | 4.29355891 |
| 29 | serotonin metabolic process (GO:0042428) | 4.08705561 |
| 30 | early endosome to late endosome transport (GO:0045022) | 4.06968923 |
| 31 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 4.04704716 |
| 32 | CDP-diacylglycerol metabolic process (GO:0046341) | 4.01459128 |
| 33 | regulation of vacuole organization (GO:0044088) | 3.94102600 |
| 34 | protein polyglutamylation (GO:0018095) | 3.93282610 |
| 35 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.86147445 |
| 36 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 3.84332414 |
| 37 | regulation of hexokinase activity (GO:1903299) | 3.79492211 |
| 38 | regulation of glucokinase activity (GO:0033131) | 3.79492211 |
| 39 | negative regulation of mast cell activation (GO:0033004) | 3.77678860 |
| 40 | positive regulation of mRNA processing (GO:0050685) | 3.73951543 |
| 41 | negative regulation of chemotaxis (GO:0050922) | 3.73010863 |
| 42 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.69084513 |
| 43 | negative regulation of establishment of protein localization to plasma membrane (GO:0090005) | 3.65610496 |
| 44 | cytoplasmic sequestering of protein (GO:0051220) | 3.62532026 |
| 45 | N-terminal protein amino acid acetylation (GO:0006474) | 3.61132337 |
| 46 | CENP-A containing nucleosome assembly (GO:0034080) | 3.59899274 |
| 47 | kinetochore assembly (GO:0051382) | 3.59677381 |
| 48 | G1 DNA damage checkpoint (GO:0044783) | 3.51444979 |
| 49 | DNA strand renaturation (GO:0000733) | 3.51132364 |
| 50 | chromatin remodeling at centromere (GO:0031055) | 3.47179720 |
| 51 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.38440434 |
| 52 | estrogen metabolic process (GO:0008210) | 3.37446670 |
| 53 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 3.35518951 |
| 54 | replicative senescence (GO:0090399) | 3.32555663 |
| 55 | regulation of helicase activity (GO:0051095) | 3.26719553 |
| 56 | histone exchange (GO:0043486) | 3.26460272 |
| 57 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.20815074 |
| 58 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.20815074 |
| 59 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.20815074 |
| 60 | primary amino compound metabolic process (GO:1901160) | 3.19763432 |
| 61 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.19547031 |
| 62 | positive regulation of mRNA metabolic process (GO:1903313) | 3.12212606 |
| 63 | negative regulation of cell cycle G2/M phase transition (GO:1902750) | 3.09586950 |
| 64 | negative regulation of fibroblast proliferation (GO:0048147) | 3.08639468 |
| 65 | regulation of DNA endoreduplication (GO:0032875) | 3.05570817 |
| 66 | positive regulation of response to oxidative stress (GO:1902884) | 3.04055448 |
| 67 | positive regulation of cellular response to oxidative stress (GO:1900409) | 3.04055448 |
| 68 | mRNA polyadenylation (GO:0006378) | 2.98160629 |
| 69 | positive regulation of chromosome segregation (GO:0051984) | 2.97510235 |
| 70 | mitotic G1/S transition checkpoint (GO:0044819) | 2.97452104 |
| 71 | regulation of centriole replication (GO:0046599) | 2.96303309 |
| 72 | negative regulation of exocytosis (GO:0045920) | 2.95946528 |
| 73 | protein localization to kinetochore (GO:0034501) | 2.95898613 |
| 74 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.90765516 |
| 75 | cellular protein catabolic process (GO:0044257) | 2.89945124 |
| 76 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.89140022 |
| 77 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.89140022 |
| 78 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.88988671 |
| 79 | autophagic vacuole assembly (GO:0000045) | 2.86326510 |
| 80 | negative regulation of autophagy (GO:0010507) | 2.85466865 |
| 81 | mitotic metaphase plate congression (GO:0007080) | 2.84800565 |
| 82 | mitotic chromosome condensation (GO:0007076) | 2.83454251 |
| 83 | mitotic sister chromatid segregation (GO:0000070) | 2.83065906 |
| 84 | histone monoubiquitination (GO:0010390) | 2.77656340 |
| 85 | regulation of macroautophagy (GO:0016241) | 2.74883979 |
| 86 | sister chromatid segregation (GO:0000819) | 2.74594121 |
| 87 | regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) | 2.72321026 |
| 88 | RNA polyadenylation (GO:0043631) | 2.70696992 |
| 89 | sodium-independent organic anion transport (GO:0043252) | 2.70609627 |
| 90 | radial glial cell differentiation (GO:0060019) | 2.70581348 |
| 91 | DNA replication checkpoint (GO:0000076) | 2.69563484 |
| 92 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.69185161 |
| 93 | sulfation (GO:0051923) | 2.69176601 |
| 94 | benzene-containing compound metabolic process (GO:0042537) | 2.68735767 |
| 95 | mitotic sister chromatid cohesion (GO:0007064) | 2.68594269 |
| 96 | G2 DNA damage checkpoint (GO:0031572) | 2.67087926 |
| 97 | meiotic chromosome segregation (GO:0045132) | 2.65077547 |
| 98 | cellular protein complex localization (GO:0034629) | 2.64056783 |
| 99 | negative regulation of leukocyte chemotaxis (GO:0002689) | 13.8730452 |
| 100 | regulation of macrophage chemotaxis (GO:0010758) | 10.5820929 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.58024139 |
| 2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.45855581 |
| 3 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 4.16597089 |
| 4 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.06851896 |
| 5 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.85732141 |
| 6 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.81398824 |
| 7 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.57213625 |
| 8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.49620704 |
| 9 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.44861830 |
| 10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.39171871 |
| 11 | FUS_26573619_Chip-Seq_HEK293_Human | 2.22677716 |
| 12 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.15274917 |
| 13 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.10245301 |
| 14 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.04011368 |
| 15 | TP53_16413492_ChIP-PET_HCT116_Human | 2.02090143 |
| 16 | E2F7_22180533_ChIP-Seq_HELA_Human | 11.0969196 |
| 17 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.93563367 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.90655307 |
| 19 | * GBX2_23144817_ChIP-Seq_PC3_Human | 1.85384406 |
| 20 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.75984277 |
| 21 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.67278385 |
| 22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.63881159 |
| 23 | AR_25329375_ChIP-Seq_VCAP_Human | 1.59260150 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.54270379 |
| 25 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.52506091 |
| 26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.47858433 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.43111491 |
| 28 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.37097175 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.36586937 |
| 30 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.35556093 |
| 31 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.33808765 |
| 32 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33808765 |
| 33 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.28523536 |
| 34 | JUN_21703547_ChIP-Seq_K562_Human | 1.25629030 |
| 35 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.25544816 |
| 36 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.24493564 |
| 37 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.23426633 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.23292437 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.23011049 |
| 40 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.22911146 |
| 41 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.21689844 |
| 42 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20736189 |
| 43 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.19911819 |
| 44 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.19502714 |
| 45 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.19197699 |
| 46 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.18564297 |
| 47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.17732978 |
| 48 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.13385546 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.12804559 |
| 50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.09377012 |
| 51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07861982 |
| 52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.07602787 |
| 53 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.07261977 |
| 54 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.07200519 |
| 55 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07089677 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06111662 |
| 57 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.05546518 |
| 58 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.05461491 |
| 59 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.04791897 |
| 60 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.03593845 |
| 61 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.02226279 |
| 62 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.01569219 |
| 63 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.01033957 |
| 64 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98564400 |
| 65 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.98559718 |
| 66 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.98131303 |
| 67 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.97702314 |
| 68 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.97702314 |
| 69 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.95804977 |
| 70 | P300_19829295_ChIP-Seq_ESCs_Human | 0.95531876 |
| 71 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.94885477 |
| 72 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.94872701 |
| 73 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.94554013 |
| 74 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.94009274 |
| 75 | TCF4_23295773_ChIP-Seq_U87_Human | 0.93447711 |
| 76 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.93282122 |
| 77 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.93275900 |
| 78 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.91153984 |
| 79 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.90946551 |
| 80 | NFYB_21822215_ChIP-Seq_K562_Human | 0.90724361 |
| 81 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.89618173 |
| 82 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89342624 |
| 83 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.89225391 |
| 84 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89161789 |
| 85 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.88757448 |
| 86 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.88123826 |
| 87 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88098257 |
| 88 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.87531981 |
| 89 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86352311 |
| 90 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.85973138 |
| 91 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.85287034 |
| 92 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84191771 |
| 93 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.83705661 |
| 94 | TBL1_22424771_ChIP-Seq_293T_Human | 0.82900908 |
| 95 | STAT3_23295773_ChIP-Seq_U87_Human | 0.82559852 |
| 96 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82201185 |
| 97 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.81905107 |
| 98 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.80431312 |
| 99 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.80351350 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.80200134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000383_abnormal_hair_follicle | 5.66133869 |
| 2 | MP0004742_abnormal_vestibular_system | 4.79027399 |
| 3 | MP0006292_abnormal_olfactory_placode | 4.28312900 |
| 4 | MP0010678_abnormal_skin_adnexa | 4.12611369 |
| 5 | MP0000427_abnormal_hair_cycle | 3.35781777 |
| 6 | MP0005379_endocrine/exocrine_gland_phen | 3.22358646 |
| 7 | MP0009053_abnormal_anal_canal | 2.76049833 |
| 8 | MP0001727_abnormal_embryo_implantation | 2.61819707 |
| 9 | MP0009697_abnormal_copulation | 2.61137101 |
| 10 | MP0000647_abnormal_sebaceous_gland | 2.56386815 |
| 11 | MP0000462_abnormal_digestive_system | 2.34636690 |
| 12 | MP0002098_abnormal_vibrissa_morphology | 2.32296852 |
| 13 | MP0004957_abnormal_blastocyst_morpholog | 2.31410269 |
| 14 | MP0010368_abnormal_lymphatic_system | 2.26488614 |
| 15 | MP0003122_maternal_imprinting | 2.19800428 |
| 16 | MP0000566_synostosis | 2.17104765 |
| 17 | MP0002396_abnormal_hematopoietic_system | 1.95520839 |
| 18 | MP0004808_abnormal_hematopoietic_stem | 1.90790012 |
| 19 | MP0008057_abnormal_DNA_replication | 1.90376205 |
| 20 | MP0008932_abnormal_embryonic_tissue | 1.86806392 |
| 21 | MP0003011_delayed_dark_adaptation | 1.82439783 |
| 22 | MP0003879_abnormal_hair_cell | 1.79824949 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.78119108 |
| 24 | MP0008875_abnormal_xenobiotic_pharmacok | 1.74944220 |
| 25 | MP0010094_abnormal_chromosome_stability | 1.74931498 |
| 26 | MP0005377_hearing/vestibular/ear_phenot | 1.73650998 |
| 27 | MP0003878_abnormal_ear_physiology | 1.73650998 |
| 28 | MP0003705_abnormal_hypodermis_morpholog | 1.71600645 |
| 29 | MP0004510_myositis | 1.66437876 |
| 30 | MP0000428_abnormal_craniofacial_morphol | 1.66285535 |
| 31 | MP0003121_genomic_imprinting | 1.57855725 |
| 32 | MP0003111_abnormal_nucleus_morphology | 1.54969287 |
| 33 | MP0009278_abnormal_bone_marrow | 1.49903540 |
| 34 | MP0008789_abnormal_olfactory_epithelium | 1.48359752 |
| 35 | MP0004885_abnormal_endolymph | 1.48207052 |
| 36 | MP0001485_abnormal_pinna_reflex | 1.41755473 |
| 37 | MP0010030_abnormal_orbit_morphology | 1.40851616 |
| 38 | MP0002282_abnormal_trachea_morphology | 1.37703285 |
| 39 | MP0000613_abnormal_salivary_gland | 1.32183172 |
| 40 | MP0001188_hyperpigmentation | 1.26155282 |
| 41 | MP0003077_abnormal_cell_cycle | 1.22852634 |
| 42 | MP0003941_abnormal_skin_development | 1.22282821 |
| 43 | MP0002102_abnormal_ear_morphology | 1.19814296 |
| 44 | MP0000579_abnormal_nail_morphology | 1.19373840 |
| 45 | MP0005499_abnormal_olfactory_system | 1.19286535 |
| 46 | MP0005394_taste/olfaction_phenotype | 1.19286535 |
| 47 | MP0002938_white_spotting | 1.18399838 |
| 48 | MP0005551_abnormal_eye_electrophysiolog | 1.15836023 |
| 49 | MP0000537_abnormal_urethra_morphology | 1.12027978 |
| 50 | MP0003315_abnormal_perineum_morphology | 1.10157171 |
| 51 | MP0001851_eye_inflammation | 1.08511398 |
| 52 | MP0001286_abnormal_eye_development | 1.07406025 |
| 53 | MP0004197_abnormal_fetal_growth/weight/ | 1.07089128 |
| 54 | MP0005501_abnormal_skin_physiology | 1.06956581 |
| 55 | MP0008872_abnormal_physiological_respon | 1.06036439 |
| 56 | MP0000750_abnormal_muscle_regeneration | 1.04909913 |
| 57 | MP0001216_abnormal_epidermal_layer | 1.03831730 |
| 58 | MP0001270_distended_abdomen | 1.02917648 |
| 59 | MP0000377_abnormal_hair_follicle | 1.01878080 |
| 60 | MP0000350_abnormal_cell_proliferation | 1.01309921 |
| 61 | MP0006054_spinal_hemorrhage | 1.00372134 |
| 62 | MP0008058_abnormal_DNA_repair | 0.98799431 |
| 63 | MP0010771_integument_phenotype | 0.95020366 |
| 64 | MP0003937_abnormal_limbs/digits/tail_de | 0.94372239 |
| 65 | MP0005187_abnormal_penis_morphology | 0.93405715 |
| 66 | MP0005310_abnormal_salivary_gland | 0.90790144 |
| 67 | MP0002970_abnormal_white_adipose | 0.89807196 |
| 68 | MP0001915_intracranial_hemorrhage | 0.89544307 |
| 69 | MP0002233_abnormal_nose_morphology | 0.89261900 |
| 70 | MP0005076_abnormal_cell_differentiation | 0.88784063 |
| 71 | MP0002210_abnormal_sex_determination | 0.86924799 |
| 72 | MP0001293_anophthalmia | 0.86386202 |
| 73 | MP0000026_abnormal_inner_ear | 0.85343508 |
| 74 | MP0002796_impaired_skin_barrier | 0.84165596 |
| 75 | MP0001879_abnormal_lymphatic_vessel | 0.83279944 |
| 76 | MP0008007_abnormal_cellular_replicative | 0.82271691 |
| 77 | MP0003656_abnormal_erythrocyte_physiolo | 0.81379291 |
| 78 | MP0002697_abnormal_eye_size | 0.77497503 |
| 79 | MP0004147_increased_porphyrin_level | 0.75595624 |
| 80 | MP0005248_abnormal_Harderian_gland | 0.74698787 |
| 81 | MP0005367_renal/urinary_system_phenotyp | 0.74351074 |
| 82 | MP0000516_abnormal_urinary_system | 0.74351074 |
| 83 | MP0009672_abnormal_birth_weight | 0.72087625 |
| 84 | MP0002234_abnormal_pharynx_morphology | 0.70500021 |
| 85 | MP0009250_abnormal_appendicular_skeleto | 0.69916555 |
| 86 | MP0002092_abnormal_eye_morphology | 0.68945620 |
| 87 | MP0003453_abnormal_keratinocyte_physiol | 0.66499929 |
| 88 | MP0009931_abnormal_skin_appearance | 0.65169302 |
| 89 | MP0003755_abnormal_palate_morphology | 0.65156026 |
| 90 | MP0001243_abnormal_dermal_layer | 0.62690673 |
| 91 | MP0003943_abnormal_hepatobiliary_system | 0.62605318 |
| 92 | MP0001958_emphysema | 0.61927672 |
| 93 | MP0003718_maternal_effect | 0.61593051 |
| 94 | MP0002114_abnormal_axial_skeleton | 0.61468357 |
| 95 | MP0001299_abnormal_eye_distance/ | 0.61220240 |
| 96 | MP0006138_congestive_heart_failure | 0.60755081 |
| 97 | MP0001764_abnormal_homeostasis | 0.60711912 |
| 98 | MP0001853_heart_inflammation | 0.58912130 |
| 99 | MP0005174_abnormal_tail_pigmentation | 0.56513176 |
| 100 | MP0005391_vision/eye_phenotype | 0.56361692 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoamputation (HP:0001218) | 9.29399153 |
| 2 | Osteolytic defects of the hand bones (HP:0009699) | 8.78473153 |
| 3 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 8.78473153 |
| 4 | Amblyopia (HP:0000646) | 7.65786236 |
| 5 | Abnormality of the parathyroid morphology (HP:0011766) | 6.98370765 |
| 6 | Poor speech (HP:0002465) | 6.18310192 |
| 7 | Nephroblastoma (Wilms tumor) (HP:0002667) | 5.71262454 |
| 8 | Embryonal renal neoplasm (HP:0011794) | 5.43096902 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 5.36870437 |
| 10 | Cerebellar dysplasia (HP:0007033) | 4.89013761 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 4.74531634 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 4.56041365 |
| 13 | Hyperparathyroidism (HP:0000843) | 3.80484976 |
| 14 | Wormian bones (HP:0002645) | 3.56451050 |
| 15 | Hyperventilation (HP:0002883) | 3.51485877 |
| 16 | Embryonal neoplasm (HP:0002898) | 3.49558540 |
| 17 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.45850954 |
| 18 | Exertional dyspnea (HP:0002875) | 3.35791663 |
| 19 | Colon cancer (HP:0003003) | 3.18184397 |
| 20 | Ectopic kidney (HP:0000086) | 3.10243446 |
| 21 | Increased intramyocellular lipid droplets (HP:0012240) | 3.04006966 |
| 22 | Hamartoma (HP:0010566) | 2.95620647 |
| 23 | Esotropia (HP:0000565) | 2.92702138 |
| 24 | Neoplasm of the adrenal cortex (HP:0100641) | 2.91278198 |
| 25 | Abnormality of renal resorption (HP:0011038) | 2.85618550 |
| 26 | Abnormal cortical bone morphology (HP:0003103) | 2.79638667 |
| 27 | Abnormal lung lobation (HP:0002101) | 2.78917277 |
| 28 | Short 4th metacarpal (HP:0010044) | 2.76857197 |
| 29 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.76857197 |
| 30 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.75162999 |
| 31 | Respiratory difficulties (HP:0002880) | 2.72786035 |
| 32 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.71907737 |
| 33 | Chromsome breakage (HP:0040012) | 2.64434204 |
| 34 | Difficulty running (HP:0009046) | 2.64152809 |
| 35 | Tapered finger (HP:0001182) | 2.59916615 |
| 36 | Facial hemangioma (HP:0000329) | 2.58186272 |
| 37 | Prostate neoplasm (HP:0100787) | 2.56764651 |
| 38 | Abnormality of the aortic arch (HP:0012303) | 2.53932246 |
| 39 | Neoplasm of the thyroid gland (HP:0100031) | 2.45374546 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.39520780 |
| 41 | Osteomyelitis (HP:0002754) | 2.39263386 |
| 42 | Renal cell carcinoma (HP:0005584) | 2.37115292 |
| 43 | Intellectual disability, severe (HP:0010864) | 2.19817049 |
| 44 | Abnormality of the 4th metacarpal (HP:0010012) | 2.19521667 |
| 45 | Papillary thyroid carcinoma (HP:0002895) | 2.18583918 |
| 46 | Neoplasm of the pancreas (HP:0002894) | 2.15011239 |
| 47 | Cerebral edema (HP:0002181) | 2.12401947 |
| 48 | Abnormality of chromosome stability (HP:0003220) | 2.08206732 |
| 49 | 3-Methylglutaconic aciduria (HP:0003535) | 2.07953984 |
| 50 | Microglossia (HP:0000171) | 2.07786858 |
| 51 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.07571574 |
| 52 | Hypoplasia of the fovea (HP:0007750) | 2.07571574 |
| 53 | Genetic anticipation (HP:0003743) | 2.07481236 |
| 54 | Duodenal stenosis (HP:0100867) | 2.03960186 |
| 55 | Small intestinal stenosis (HP:0012848) | 2.03960186 |
| 56 | Acute myeloid leukemia (HP:0004808) | 2.00097659 |
| 57 | Mitochondrial inheritance (HP:0001427) | 1.95206306 |
| 58 | Oligodactyly (HP:0012165) | 1.92928640 |
| 59 | Congenital primary aphakia (HP:0007707) | 1.88360320 |
| 60 | Hypercalcemia (HP:0003072) | 1.87965810 |
| 61 | Hyperphosphaturia (HP:0003109) | 1.87904524 |
| 62 | Partial agenesis of the corpus callosum (HP:0001338) | 1.87144046 |
| 63 | Abnormal hair whorl (HP:0010721) | 1.85492593 |
| 64 | Myelodysplasia (HP:0002863) | 1.83105056 |
| 65 | Gait imbalance (HP:0002141) | 1.82409362 |
| 66 | Abnormality of the duodenum (HP:0002246) | 1.81432846 |
| 67 | Hyperglycinuria (HP:0003108) | 1.78418733 |
| 68 | Small hand (HP:0200055) | 1.75566546 |
| 69 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.74950124 |
| 70 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.73588315 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.72288603 |
| 72 | Glycosuria (HP:0003076) | 1.72288603 |
| 73 | Birth length less than 3rd percentile (HP:0003561) | 1.70263161 |
| 74 | Acute necrotizing encephalopathy (HP:0006965) | 1.67665002 |
| 75 | Abnormality of the fovea (HP:0000493) | 1.67661718 |
| 76 | Thyroid carcinoma (HP:0002890) | 1.67421249 |
| 77 | Meckel diverticulum (HP:0002245) | 1.65202256 |
| 78 | Sloping forehead (HP:0000340) | 1.62159413 |
| 79 | Urinary incontinence (HP:0000020) | 1.61792226 |
| 80 | Abnormality of the preputium (HP:0100587) | 1.61722500 |
| 81 | Nephrogenic diabetes insipidus (HP:0009806) | 1.60978131 |
| 82 | Acute lymphatic leukemia (HP:0006721) | 1.59935047 |
| 83 | Tetraparesis (HP:0002273) | 1.59372217 |
| 84 | Heterotopia (HP:0002282) | 1.59336030 |
| 85 | Abnormality of cochlea (HP:0000375) | 1.58677665 |
| 86 | Hypermetropia (HP:0000540) | 1.57911370 |
| 87 | Optic nerve hypoplasia (HP:0000609) | 1.57769428 |
| 88 | Capillary hemangiomas (HP:0005306) | 1.57705342 |
| 89 | Poor coordination (HP:0002370) | 1.56243717 |
| 90 | Volvulus (HP:0002580) | 1.55692006 |
| 91 | Renal dysplasia (HP:0000110) | 1.54602528 |
| 92 | Increased CSF lactate (HP:0002490) | 1.54265763 |
| 93 | Psychosis (HP:0000709) | 1.54167432 |
| 94 | Tubulointerstitial nephritis (HP:0001970) | 1.52175338 |
| 95 | Clubbing of toes (HP:0100760) | 1.51428551 |
| 96 | Cupped ear (HP:0000378) | 1.51116762 |
| 97 | Abnormal urine phosphate concentration (HP:0012599) | 1.50679002 |
| 98 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.50338522 |
| 99 | Adrenal hypoplasia (HP:0000835) | 1.48539812 |
| 100 | Hyperkalemia (HP:0002153) | 1.46961113 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WEE1 | 7.70739355 |
| 2 | BRSK1 | 4.94268709 |
| 3 | PBK | 3.57374382 |
| 4 | TAF1 | 3.18254496 |
| 5 | VRK2 | 2.82870698 |
| 6 | MAP3K10 | 2.52227083 |
| 7 | SMG1 | 2.45687385 |
| 8 | NEK9 | 2.13170845 |
| 9 | BRSK2 | 10.5461590 |
| 10 | PNCK | 1.80532662 |
| 11 | NUAK1 | 1.71927981 |
| 12 | BMPR1B | 1.48989821 |
| 13 | MKNK2 | 1.44148723 |
| 14 | CDK4 | 1.39210673 |
| 15 | CASK | 1.23499113 |
| 16 | CDC7 | 1.19896830 |
| 17 | EIF2AK2 | 1.16388732 |
| 18 | BUB1 | 1.08077290 |
| 19 | MST4 | 0.91924032 |
| 20 | VRK1 | 0.91124303 |
| 21 | MKNK1 | 0.86879199 |
| 22 | AURKA | 0.86646094 |
| 23 | CAMK1G | 0.86386476 |
| 24 | MELK | 0.82422016 |
| 25 | EPHB2 | 0.80645628 |
| 26 | ZAK | 0.78072697 |
| 27 | PLK1 | 0.77155221 |
| 28 | TNIK | 0.77043761 |
| 29 | EIF2AK1 | 0.75130322 |
| 30 | PLK4 | 0.70307733 |
| 31 | BRD4 | 0.67798294 |
| 32 | SCYL2 | 0.67770837 |
| 33 | MAPKAPK5 | 0.65306468 |
| 34 | PLK3 | 0.64928661 |
| 35 | DYRK3 | 0.64456912 |
| 36 | MAP3K13 | 0.62874142 |
| 37 | TTK | 0.61615801 |
| 38 | HIPK2 | 0.58009459 |
| 39 | MAP3K12 | 0.57127070 |
| 40 | WNK3 | 0.56812925 |
| 41 | WNK4 | 0.55752581 |
| 42 | CDK3 | 0.55353905 |
| 43 | PINK1 | 0.52331966 |
| 44 | UHMK1 | 0.50163337 |
| 45 | NEK2 | 0.49442757 |
| 46 | ACVR1B | 0.47131330 |
| 47 | NME1 | 0.46826615 |
| 48 | CSNK1G2 | 0.45196777 |
| 49 | GRK5 | 0.42917577 |
| 50 | CHEK2 | 0.41791089 |
| 51 | CSNK1A1L | 0.41053686 |
| 52 | RPS6KA4 | 0.39541967 |
| 53 | LATS1 | 0.38594619 |
| 54 | CSNK1G3 | 0.37474704 |
| 55 | CSNK1G1 | 0.37441030 |
| 56 | NEK1 | 0.36099160 |
| 57 | TSSK6 | 0.33589426 |
| 58 | CDK9 | 0.32181408 |
| 59 | ATR | 0.27560097 |
| 60 | CSNK1D | 0.26699060 |
| 61 | TAOK3 | 0.26259540 |
| 62 | MAP3K7 | 0.26122286 |
| 63 | RPS6KA1 | 0.25881926 |
| 64 | AURKB | 0.25853705 |
| 65 | SGK2 | 0.22860724 |
| 66 | FLT3 | 0.22639359 |
| 67 | EIF2AK3 | 0.21262204 |
| 68 | CDK7 | 0.19060937 |
| 69 | CAMKK2 | 0.16208460 |
| 70 | DYRK2 | 0.15779767 |
| 71 | YES1 | 0.14590469 |
| 72 | WNK1 | 0.13663059 |
| 73 | STK3 | 0.13471377 |
| 74 | STK11 | 0.12390920 |
| 75 | MAP4K2 | 0.11950054 |
| 76 | CDK8 | 0.11936176 |
| 77 | MAPK14 | 0.11051453 |
| 78 | PRKG1 | 0.10901208 |
| 79 | ATM | 0.10776202 |
| 80 | CDK1 | 0.10176020 |
| 81 | MAPK15 | 0.09479717 |
| 82 | GSK3A | 0.08743456 |
| 83 | CSNK2A1 | 0.07858800 |
| 84 | OXSR1 | 0.07065666 |
| 85 | CSNK1E | 0.06136731 |
| 86 | TEC | 0.05481495 |
| 87 | ADRBK2 | 0.05180607 |
| 88 | STK38L | 0.04547709 |
| 89 | CDK6 | 0.04224152 |
| 90 | TRPM7 | 0.04007477 |
| 91 | STK39 | 0.03791644 |
| 92 | DAPK3 | 0.03352043 |
| 93 | CDK2 | 0.03059186 |
| 94 | MAP3K14 | 0.01714488 |
| 95 | CDK5 | 0.00984818 |
| 96 | CSNK2A2 | 0.00947375 |
| 97 | PRKAA1 | 0.00688227 |
| 98 | ERBB4 | 0.00331822 |
| 99 | SGK1 | 0.00274859 |
| 100 | STK16 | -0.0077014 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Regulation of autophagy_Homo sapiens_hsa04140 | 5.52516069 |
| 2 | Cell cycle_Homo sapiens_hsa04110 | 4.81778197 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.18212379 |
| 4 | Homologous recombination_Homo sapiens_hsa03440 | 3.16348404 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.08392327 |
| 6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.23469109 |
| 7 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.15925239 |
| 8 | Base excision repair_Homo sapiens_hsa03410 | 2.15925227 |
| 9 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.88181498 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 1.87683209 |
| 11 | ABC transporters_Homo sapiens_hsa02010 | 1.85456076 |
| 12 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.82580519 |
| 13 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.81191631 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.77743614 |
| 15 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.75649010 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.73996464 |
| 17 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.69438866 |
| 18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.55584563 |
| 19 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.53917244 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.47539218 |
| 21 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.46227317 |
| 22 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.45386439 |
| 23 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.41566453 |
| 24 | Ribosome_Homo sapiens_hsa03010 | 1.41196120 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40560734 |
| 26 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.38389479 |
| 27 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.36692572 |
| 28 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.30411593 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.26286104 |
| 30 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.23911768 |
| 31 | Sulfur relay system_Homo sapiens_hsa04122 | 1.23201386 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.20305874 |
| 33 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.09483942 |
| 34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.06839975 |
| 35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.04699676 |
| 36 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.04011222 |
| 37 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.00182161 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.98242814 |
| 39 | Olfactory transduction_Homo sapiens_hsa04740 | 0.97954716 |
| 40 | Protein export_Homo sapiens_hsa03060 | 0.95479276 |
| 41 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.95400323 |
| 42 | RNA degradation_Homo sapiens_hsa03018 | 0.94775806 |
| 43 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.93485267 |
| 44 | Phototransduction_Homo sapiens_hsa04744 | 0.89898900 |
| 45 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.88667729 |
| 46 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.87980192 |
| 47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.87338915 |
| 48 | Lysine degradation_Homo sapiens_hsa00310 | 0.86298578 |
| 49 | Prostate cancer_Homo sapiens_hsa05215 | 0.85264306 |
| 50 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.85242884 |
| 51 | Thyroid cancer_Homo sapiens_hsa05216 | 0.83654677 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.82557497 |
| 53 | Adherens junction_Homo sapiens_hsa04520 | 0.82003368 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.80439107 |
| 55 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.79527299 |
| 56 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.78730205 |
| 57 | Alcoholism_Homo sapiens_hsa05034 | 0.74759493 |
| 58 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.71901547 |
| 59 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.71443193 |
| 60 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.69991049 |
| 61 | Huntingtons disease_Homo sapiens_hsa05016 | 0.68083210 |
| 62 | Spliceosome_Homo sapiens_hsa03040 | 0.65820378 |
| 63 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.64307927 |
| 64 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.63955379 |
| 65 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.62911251 |
| 66 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.61229534 |
| 67 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.57852264 |
| 68 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.57148866 |
| 69 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.56448407 |
| 70 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.54196011 |
| 71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.53810385 |
| 72 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.52229638 |
| 73 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49596143 |
| 74 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.44231879 |
| 75 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.43601002 |
| 76 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42837604 |
| 77 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.41572430 |
| 78 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.39135774 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39094223 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.35507253 |
| 81 | Parkinsons disease_Homo sapiens_hsa05012 | 0.33297381 |
| 82 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.33212747 |
| 83 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.32195019 |
| 84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.31559786 |
| 85 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.29272564 |
| 86 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.28111065 |
| 87 | Renin secretion_Homo sapiens_hsa04924 | 0.28033682 |
| 88 | Melanoma_Homo sapiens_hsa05218 | 0.27622345 |
| 89 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.26468076 |
| 90 | Axon guidance_Homo sapiens_hsa04360 | 0.25483382 |
| 91 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25400653 |
| 92 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.24980647 |
| 93 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.24699477 |
| 94 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24476321 |
| 95 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.24345670 |
| 96 | Colorectal cancer_Homo sapiens_hsa05210 | 0.23985805 |
| 97 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.22198352 |
| 98 | Pathways in cancer_Homo sapiens_hsa05200 | 0.21105481 |
| 99 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.20055738 |
| 100 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.18917296 |

