

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.86387840 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.59634065 |
| 3 | negative regulation of cell killing (GO:0031342) | 6.59634065 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 6.32511996 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 6.32511996 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.32511996 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.32511996 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.32511996 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 6.32511996 |
| 10 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.75284125 |
| 11 | neutrophil activation involved in immune response (GO:0002283) | 5.63949188 |
| 12 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.49328094 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.46985810 |
| 14 | detection of other organism (GO:0098543) | 5.43384803 |
| 15 | leukocyte migration involved in inflammatory response (GO:0002523) | 5.31600440 |
| 16 | detection of bacterium (GO:0016045) | 5.27909218 |
| 17 | macrophage activation involved in immune response (GO:0002281) | 5.23462612 |
| 18 | leukocyte aggregation (GO:0070486) | 5.17250376 |
| 19 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.11122515 |
| 20 | response to peptidoglycan (GO:0032494) | 4.82660594 |
| 21 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.76085379 |
| 22 | detection of external biotic stimulus (GO:0098581) | 4.72946652 |
| 23 | neutrophil activation (GO:0042119) | 4.63709022 |
| 24 | detection of molecule of bacterial origin (GO:0032490) | 4.60875030 |
| 25 | cellular extravasation (GO:0045123) | 4.60402390 |
| 26 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.58788259 |
| 27 | respiratory burst (GO:0045730) | 4.50179415 |
| 28 | response to interleukin-15 (GO:0070672) | 4.47473762 |
| 29 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.37666968 |
| 30 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.36984717 |
| 31 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.36408561 |
| 32 | negative regulation of interleukin-12 production (GO:0032695) | 4.35054950 |
| 33 | response to host immune response (GO:0052572) | 4.22060018 |
| 34 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.22060018 |
| 35 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.15799588 |
| 36 | regulation of gamma-delta T cell activation (GO:0046643) | 4.13880204 |
| 37 | detection of biotic stimulus (GO:0009595) | 4.11718099 |
| 38 | granulocyte activation (GO:0036230) | 4.11096697 |
| 39 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.98704731 |
| 40 | cellular response to interleukin-15 (GO:0071350) | 3.96461235 |
| 41 | neutrophil mediated immunity (GO:0002446) | 3.93047587 |
| 42 | regulation of mast cell degranulation (GO:0043304) | 3.91481530 |
| 43 | microglial cell activation (GO:0001774) | 3.89685723 |
| 44 | response to host (GO:0075136) | 3.86947215 |
| 45 | response to host defenses (GO:0052200) | 3.86947215 |
| 46 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.86947215 |
| 47 | myeloid cell activation involved in immune response (GO:0002275) | 3.86395142 |
| 48 | immunoglobulin mediated immune response (GO:0016064) | 3.81187751 |
| 49 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.80386522 |
| 50 | macrophage activation (GO:0042116) | 3.79294352 |
| 51 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.77647758 |
| 52 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.77124207 |
| 53 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.71480469 |
| 54 | germinal center formation (GO:0002467) | 3.65605998 |
| 55 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.62308619 |
| 56 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.61401588 |
| 57 | negative regulation of phagocytosis (GO:0050765) | 3.58856456 |
| 58 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.57553211 |
| 59 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.57553211 |
| 60 | leukocyte degranulation (GO:0043299) | 3.55875191 |
| 61 | negative regulation of T cell mediated immunity (GO:0002710) | 3.51839095 |
| 62 | regulation of leukocyte degranulation (GO:0043300) | 3.42613370 |
| 63 | myeloid leukocyte mediated immunity (GO:0002444) | 3.37696951 |
| 64 | cellular response to type I interferon (GO:0071357) | 3.35233251 |
| 65 | type I interferon signaling pathway (GO:0060337) | 3.35233251 |
| 66 | response to type I interferon (GO:0034340) | 3.34640275 |
| 67 | defense response to protozoan (GO:0042832) | 3.33348319 |
| 68 | response to muramyl dipeptide (GO:0032495) | 3.33087490 |
| 69 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.32566449 |
| 70 | regulation of mast cell activation (GO:0033003) | 3.30772479 |
| 71 | positive regulation of mast cell activation (GO:0033005) | 3.30397556 |
| 72 | B cell receptor signaling pathway (GO:0050853) | 3.22627165 |
| 73 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.19651137 |
| 74 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.16803824 |
| 75 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.15340405 |
| 76 | regulation of T cell tolerance induction (GO:0002664) | 3.14534647 |
| 77 | regulation of B cell differentiation (GO:0045577) | 3.13987327 |
| 78 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.13022038 |
| 79 | negative regulation of interleukin-6 production (GO:0032715) | 3.12515307 |
| 80 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.11604384 |
| 81 | regulation of tolerance induction (GO:0002643) | 3.09892461 |
| 82 | regulation of regulated secretory pathway (GO:1903305) | 3.07333760 |
| 83 | neutrophil chemotaxis (GO:0030593) | 3.06103569 |
| 84 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.04021499 |
| 85 | negative regulation of type 2 immune response (GO:0002829) | 3.02299348 |
| 86 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.98931297 |
| 87 | neutrophil migration (GO:1990266) | 2.98211686 |
| 88 | B cell mediated immunity (GO:0019724) | 2.96467295 |
| 89 | tolerance induction (GO:0002507) | 2.95800892 |
| 90 | dendritic cell migration (GO:0036336) | 2.95473924 |
| 91 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.94714938 |
| 92 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.92530265 |
| 93 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.92197555 |
| 94 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.92197555 |
| 95 | dendritic cell chemotaxis (GO:0002407) | 2.91125130 |
| 96 | negative regulation of innate immune response (GO:0045824) | 2.89931211 |
| 97 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.89670773 |
| 98 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.88403711 |
| 99 | myeloid leukocyte activation (GO:0002274) | 2.88250326 |
| 100 | positive regulation of B cell differentiation (GO:0045579) | 2.88212077 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.47352661 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.47276211 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.70233793 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.51233728 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.29812692 |
| 6 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.94476482 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.80836281 |
| 8 | * SPI1_23127762_ChIP-Seq_K562_Human | 2.74653751 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.74405345 |
| 10 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.68060104 |
| 11 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.61453049 |
| 12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.54138879 |
| 13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.51906277 |
| 14 | MAF_26560356_Chip-Seq_TH1_Human | 2.46822629 |
| 15 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.41344029 |
| 16 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.37988472 |
| 17 | MYC_22102868_ChIP-Seq_BL_Human | 2.31935040 |
| 18 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.31242145 |
| 19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.30104398 |
| 20 | UTX_26944678_Chip-Seq_JUKART_Human | 2.27829156 |
| 21 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.27603826 |
| 22 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.27388943 |
| 23 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.26283454 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.21754046 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.20719839 |
| 26 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.20430127 |
| 27 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.15939575 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.15250912 |
| 29 | MYB_26560356_Chip-Seq_TH2_Human | 2.09351719 |
| 30 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.05131883 |
| 31 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.01743511 |
| 32 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.97953688 |
| 33 | MAF_26560356_Chip-Seq_TH2_Human | 1.97660957 |
| 34 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.95383808 |
| 35 | MYB_26560356_Chip-Seq_TH1_Human | 1.94317579 |
| 36 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.94234022 |
| 37 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.93029557 |
| 38 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.91750606 |
| 39 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91137963 |
| 40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.88058536 |
| 41 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.84446637 |
| 42 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.73332463 |
| 43 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.72821476 |
| 44 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.65578962 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.61229257 |
| 46 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.60673045 |
| 47 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.60265093 |
| 48 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.57413760 |
| 49 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.53697429 |
| 50 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.52455730 |
| 51 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.50024755 |
| 52 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.47681292 |
| 53 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.45293463 |
| 54 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.43091631 |
| 55 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.42176330 |
| 56 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.39502828 |
| 57 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.38972431 |
| 58 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.38220164 |
| 59 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.38005281 |
| 60 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.37689021 |
| 61 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.36391944 |
| 62 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.35345958 |
| 63 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33246714 |
| 64 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.31429161 |
| 65 | GATA1_19941826_ChIP-Seq_K562_Human | 1.30613722 |
| 66 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.29887859 |
| 67 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28960233 |
| 68 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.27370074 |
| 69 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.26759605 |
| 70 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.26748905 |
| 71 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.26473882 |
| 72 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.25708420 |
| 73 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.25423163 |
| 74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.24879059 |
| 75 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23813234 |
| 76 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.23582260 |
| 77 | P68_20966046_ChIP-Seq_HELA_Human | 1.18670485 |
| 78 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.17384357 |
| 79 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.17328011 |
| 80 | GATA3_26560356_Chip-Seq_TH2_Human | 1.14594500 |
| 81 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.14513076 |
| 82 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.14193773 |
| 83 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.14155024 |
| 84 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10990546 |
| 85 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.10827590 |
| 86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.10513608 |
| 87 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.10343503 |
| 88 | KDM2B_26808549_Chip-Seq_K562_Human | 1.07868933 |
| 89 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.06915647 |
| 90 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.06861886 |
| 91 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.05394710 |
| 92 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.04246780 |
| 93 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.02241423 |
| 94 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.01675157 |
| 95 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99823016 |
| 96 | GATA2_19941826_ChIP-Seq_K562_Human | 0.98502512 |
| 97 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.98333258 |
| 98 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97824089 |
| 99 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.95577433 |
| 100 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.94972834 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.28308748 |
| 2 | MP0003436_decreased_susceptibility_to | 4.62541899 |
| 3 | MP0003303_peritoneal_inflammation | 3.80347714 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.39233931 |
| 5 | MP0002419_abnormal_innate_immunity | 3.31079079 |
| 6 | MP0005025_abnormal_response_to | 2.95906938 |
| 7 | MP0001790_abnormal_immune_system | 2.84945677 |
| 8 | MP0005387_immune_system_phenotype | 2.84945677 |
| 9 | MP0001800_abnormal_humoral_immune | 2.83801537 |
| 10 | MP0000685_abnormal_immune_system | 2.75141812 |
| 11 | MP0009785_altered_susceptibility_to | 2.70974819 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.66818814 |
| 13 | MP0002132_abnormal_respiratory_system | 2.66164281 |
| 14 | MP0005671_abnormal_response_to | 2.63610827 |
| 15 | MP0002723_abnormal_immune_serum | 2.57512211 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.54232248 |
| 17 | MP0001819_abnormal_immune_cell | 2.51910730 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.40796593 |
| 19 | MP0006082_CNS_inflammation | 2.38698766 |
| 20 | MP0003300_gastrointestinal_ulcer | 2.33309754 |
| 21 | MP0001533_abnormal_skeleton_physiology | 2.24569531 |
| 22 | MP0008260_abnormal_autophagy | 2.19511095 |
| 23 | MP0003191_abnormal_cellular_cholesterol | 2.17795888 |
| 24 | MP0002396_abnormal_hematopoietic_system | 2.09835429 |
| 25 | MP0009278_abnormal_bone_marrow | 2.07403757 |
| 26 | MP0002405_respiratory_system_inflammati | 2.06259170 |
| 27 | MP0003763_abnormal_thymus_physiology | 1.96280059 |
| 28 | MP0002398_abnormal_bone_marrow | 1.93814191 |
| 29 | MP0002148_abnormal_hypersensitivity_rea | 1.92055686 |
| 30 | MP0000716_abnormal_immune_system | 1.87954920 |
| 31 | MP0005464_abnormal_platelet_physiology | 1.87583966 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 1.76241110 |
| 33 | MP0003828_pulmonary_edema | 1.72421350 |
| 34 | MP0010155_abnormal_intestine_physiology | 1.71217207 |
| 35 | MP0003172_abnormal_lysosome_physiology | 1.71206332 |
| 36 | MP0005451_abnormal_body_composition | 1.67661504 |
| 37 | MP0004381_abnormal_hair_follicle | 1.66807982 |
| 38 | MP0003866_abnormal_defecation | 1.66378183 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.65910253 |
| 40 | MP0003183_abnormal_peptide_metabolism | 1.64551661 |
| 41 | MP0005377_hearing/vestibular/ear_phenot | 1.63777640 |
| 42 | MP0003878_abnormal_ear_physiology | 1.63777640 |
| 43 | MP0004947_skin_inflammation | 1.61329041 |
| 44 | MP0002722_abnormal_immune_system | 1.60761548 |
| 45 | MP0000689_abnormal_spleen_morphology | 1.55398186 |
| 46 | MP0000703_abnormal_thymus_morphology | 1.53767293 |
| 47 | MP0004510_myositis | 1.49647013 |
| 48 | MP0002429_abnormal_blood_cell | 1.48499176 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.47424733 |
| 50 | MP0005310_abnormal_salivary_gland | 1.45675596 |
| 51 | MP0008469_abnormal_protein_level | 1.41620076 |
| 52 | MP0009333_abnormal_splenocyte_physiolog | 1.39991292 |
| 53 | MP0009764_decreased_sensitivity_to | 1.38643109 |
| 54 | MP0005397_hematopoietic_system_phenotyp | 1.36344689 |
| 55 | MP0001545_abnormal_hematopoietic_system | 1.36344689 |
| 56 | MP0004883_abnormal_blood_vessel | 1.32895696 |
| 57 | MP0001851_eye_inflammation | 1.29539159 |
| 58 | MP0000858_altered_metastatic_potential | 1.18478011 |
| 59 | MP0002998_abnormal_bone_remodeling | 1.13467830 |
| 60 | MP0003075_altered_response_to | 1.04665174 |
| 61 | MP0005164_abnormal_response_to | 1.01872010 |
| 62 | MP0008004_abnormal_stomach_pH | 0.99558924 |
| 63 | MP0001986_abnormal_taste_sensitivity | 0.97388417 |
| 64 | MP0003690_abnormal_glial_cell | 0.91843629 |
| 65 | MP0001873_stomach_inflammation | 0.90992880 |
| 66 | MP0005390_skeleton_phenotype | 0.89949351 |
| 67 | MP0001663_abnormal_digestive_system | 0.85615546 |
| 68 | MP0005083_abnormal_biliary_tract | 0.84473275 |
| 69 | MP0004808_abnormal_hematopoietic_stem | 0.82604157 |
| 70 | MP0003045_fibrosis | 0.81019637 |
| 71 | MP0005166_decreased_susceptibility_to | 0.80812105 |
| 72 | MP0004858_abnormal_nervous_system | 0.79424875 |
| 73 | MP0000490_abnormal_crypts_of | 0.79322984 |
| 74 | MP0005248_abnormal_Harderian_gland | 0.77510979 |
| 75 | MP0000678_abnormal_parathyroid_gland | 0.74889663 |
| 76 | MP0005076_abnormal_cell_differentiation | 0.72661861 |
| 77 | MP0009763_increased_sensitivity_to | 0.69500684 |
| 78 | MP0005075_abnormal_melanosome_morpholog | 0.66668750 |
| 79 | MP0002928_abnormal_bile_duct | 0.66420333 |
| 80 | MP0003806_abnormal_nucleotide_metabolis | 0.64440193 |
| 81 | MP0009765_abnormal_xenobiotic_induced | 0.63548074 |
| 82 | MP0003448_altered_tumor_morphology | 0.63147776 |
| 83 | MP0002933_joint_inflammation | 0.61891299 |
| 84 | MP0002166_altered_tumor_susceptibility | 0.60757857 |
| 85 | MP0003795_abnormal_bone_structure | 0.60251237 |
| 86 | MP0003656_abnormal_erythrocyte_physiolo | 0.60250639 |
| 87 | MP0002653_abnormal_ependyma_morphology | 0.59824567 |
| 88 | MP0005410_abnormal_fertilization | 0.59247330 |
| 89 | MP0000015_abnormal_ear_pigmentation | 0.58845827 |
| 90 | MP0008874_decreased_physiological_sensi | 0.58569865 |
| 91 | MP0005319_abnormal_enzyme/_coenzyme | 0.57130581 |
| 92 | MP0002138_abnormal_hepatobiliary_system | 0.57127199 |
| 93 | MP0000343_altered_response_to | 0.55868394 |
| 94 | MP0000470_abnormal_stomach_morphology | 0.54628195 |
| 95 | MP0005058_abnormal_lysosome_morphology | 0.54305939 |
| 96 | MP0003705_abnormal_hypodermis_morpholog | 0.53295681 |
| 97 | MP0003221_abnormal_cardiomyocyte_apopto | 0.52789645 |
| 98 | MP0000249_abnormal_blood_vessel | 0.51597214 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.51493617 |
| 100 | MP0004130_abnormal_muscle_cell | 0.48008346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 7.13168785 |
| 2 | Myositis (HP:0100614) | 6.32417716 |
| 3 | Recurrent abscess formation (HP:0002722) | 6.22913512 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 6.01152677 |
| 5 | Orchitis (HP:0100796) | 5.98654933 |
| 6 | Abnormality of macrophages (HP:0004311) | 5.58852089 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 5.51179365 |
| 8 | Optic neuritis (HP:0100653) | 5.51179365 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.25084001 |
| 10 | Stomatitis (HP:0010280) | 5.21086534 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.81296935 |
| 12 | Hypochromic microcytic anemia (HP:0004840) | 4.68817151 |
| 13 | Gastrointestinal infarctions (HP:0005244) | 4.65801251 |
| 14 | Obstructive lung disease (HP:0006536) | 4.54899415 |
| 15 | Chronic obstructive pulmonary disease (HP:0006510) | 4.54899415 |
| 16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.25346116 |
| 17 | Recurrent fungal infections (HP:0002841) | 4.24471354 |
| 18 | Increased IgE level (HP:0003212) | 4.20420296 |
| 19 | Mediastinal lymphadenopathy (HP:0100721) | 4.19684718 |
| 20 | Meningitis (HP:0001287) | 4.08087314 |
| 21 | Keratoconjunctivitis sicca (HP:0001097) | 4.01892931 |
| 22 | Hypochromic anemia (HP:0001931) | 3.99339883 |
| 23 | Recurrent skin infections (HP:0001581) | 3.96193454 |
| 24 | Gingivitis (HP:0000230) | 3.85172251 |
| 25 | Encephalitis (HP:0002383) | 3.80540705 |
| 26 | Keratoconjunctivitis (HP:0001096) | 3.72195613 |
| 27 | Spontaneous hematomas (HP:0007420) | 3.71259539 |
| 28 | Prolonged bleeding time (HP:0003010) | 3.64101331 |
| 29 | Urticaria (HP:0001025) | 3.59595605 |
| 30 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.56318780 |
| 31 | Recurrent cutaneous fungal infections (HP:0011370) | 3.56318780 |
| 32 | Episodic fever (HP:0001954) | 3.53571811 |
| 33 | Peritonitis (HP:0002586) | 3.38684001 |
| 34 | Vasculitis (HP:0002633) | 3.36405724 |
| 35 | Chest pain (HP:0100749) | 3.33506267 |
| 36 | Cellulitis (HP:0100658) | 3.28660441 |
| 37 | Anorexia (HP:0002039) | 3.03942283 |
| 38 | Hemoptysis (HP:0002105) | 3.02384539 |
| 39 | Inflammation of the large intestine (HP:0002037) | 2.87861483 |
| 40 | Gastrointestinal inflammation (HP:0004386) | 2.82585963 |
| 41 | Metaphyseal cupping (HP:0003021) | 2.78162763 |
| 42 | Arterial thrombosis (HP:0004420) | 2.77871653 |
| 43 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.75637850 |
| 44 | Gingival bleeding (HP:0000225) | 2.75476915 |
| 45 | Leukocytosis (HP:0001974) | 2.71994933 |
| 46 | Pustule (HP:0200039) | 2.69984757 |
| 47 | Pulmonary infiltrates (HP:0002113) | 2.69542818 |
| 48 | Microcytic anemia (HP:0001935) | 2.68137754 |
| 49 | Pulmonary embolism (HP:0002204) | 2.66976508 |
| 50 | Epistaxis (HP:0000421) | 2.65515756 |
| 51 | Panhypogammaglobulinemia (HP:0003139) | 2.55451153 |
| 52 | Amyloidosis (HP:0011034) | 2.51360271 |
| 53 | Petechiae (HP:0000967) | 2.50701859 |
| 54 | Osteomyelitis (HP:0002754) | 2.48619899 |
| 55 | Abnormality of the peritoneum (HP:0002585) | 2.47734444 |
| 56 | Granulocytopenia (HP:0001913) | 2.42954482 |
| 57 | Abnormality of T cells (HP:0002843) | 2.40451328 |
| 58 | Sepsis (HP:0100806) | 2.38729032 |
| 59 | T lymphocytopenia (HP:0005403) | 2.36609494 |
| 60 | Increased IgM level (HP:0003496) | 2.35271593 |
| 61 | Abnormality of the pleura (HP:0002103) | 2.33039771 |
| 62 | Premature loss of primary teeth (HP:0006323) | 2.32171198 |
| 63 | Abnormality of T cell number (HP:0011839) | 2.30765243 |
| 64 | Abnormality of T cell physiology (HP:0011840) | 2.29575272 |
| 65 | Lymphopenia (HP:0001888) | 2.26022573 |
| 66 | Recurrent viral infections (HP:0004429) | 2.22540255 |
| 67 | Gangrene (HP:0100758) | 2.20249233 |
| 68 | Acne (HP:0001061) | 2.19531470 |
| 69 | Abnormality of the endocardium (HP:0004306) | 2.18905744 |
| 70 | Slow saccadic eye movements (HP:0000514) | 2.17538861 |
| 71 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.17228851 |
| 72 | Colitis (HP:0002583) | 2.16814953 |
| 73 | Difficulty running (HP:0009046) | 2.11413731 |
| 74 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.10699095 |
| 75 | Hypergammaglobulinemia (HP:0010702) | 2.10217560 |
| 76 | Keratitis (HP:0000491) | 2.09211904 |
| 77 | Nasal polyposis (HP:0100582) | 2.06876226 |
| 78 | Hepatosplenomegaly (HP:0001433) | 2.05046568 |
| 79 | Glomerulopathy (HP:0100820) | 2.04387414 |
| 80 | Skin ulcer (HP:0200042) | 2.02114403 |
| 81 | Acute hepatic failure (HP:0006554) | 2.00258282 |
| 82 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.98794133 |
| 83 | Abnormal platelet volume (HP:0011876) | 1.98094161 |
| 84 | Abnormality of the pericardium (HP:0001697) | 1.97314479 |
| 85 | Recurrent pneumonia (HP:0006532) | 1.96635815 |
| 86 | Cheilitis (HP:0100825) | 1.95783355 |
| 87 | Abnormality of the fingertips (HP:0001211) | 1.94312034 |
| 88 | Vertigo (HP:0002321) | 1.93678249 |
| 89 | Polycythemia (HP:0001901) | 1.92477008 |
| 90 | Toxemia of pregnancy (HP:0100603) | 1.89515237 |
| 91 | Increased serum ferritin (HP:0003281) | 1.87752761 |
| 92 | Purpura (HP:0000979) | 1.86812656 |
| 93 | Abnormality of iron homeostasis (HP:0011031) | 1.86407071 |
| 94 | Chronic otitis media (HP:0000389) | 1.84107940 |
| 95 | Hypermelanotic macule (HP:0001034) | 1.80787072 |
| 96 | Eosinophilia (HP:0001880) | 1.78312123 |
| 97 | IgM deficiency (HP:0002850) | 1.77536266 |
| 98 | Recurrent lower respiratory tract infections (HP:0002783) | 1.73739669 |
| 99 | Recurrent sinusitis (HP:0011108) | 1.72843361 |
| 100 | Skin rash (HP:0000988) | 1.68653551 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.95962319 |
| 2 | IRAK4 | 3.51266358 |
| 3 | MAP4K1 | 3.49303496 |
| 4 | ERN1 | 3.37618510 |
| 5 | MAP2K3 | 3.12054910 |
| 6 | TNK2 | 3.02019719 |
| 7 | BLK | 2.92466241 |
| 8 | CSK | 2.61920288 |
| 9 | TYK2 | 2.59970701 |
| 10 | EPHB1 | 2.57299324 |
| 11 | GRK6 | 2.37788634 |
| 12 | FES | 2.32808434 |
| 13 | TAOK1 | 2.19010230 |
| 14 | ZAP70 | 1.95456982 |
| 15 | MAP3K3 | 1.85977573 |
| 16 | MAP3K11 | 1.84884575 |
| 17 | HCK | 1.82119911 |
| 18 | BTK | 1.75139714 |
| 19 | FGR | 1.72693803 |
| 20 | JAK3 | 1.64959584 |
| 21 | PRPF4B | 1.57926672 |
| 22 | KSR2 | 1.56172350 |
| 23 | TXK | 1.51056858 |
| 24 | SIK3 | 1.49525244 |
| 25 | JAK2 | 1.40579721 |
| 26 | MARK2 | 1.39164310 |
| 27 | SYK | 1.38406542 |
| 28 | TRIB3 | 1.37428828 |
| 29 | MAP3K1 | 1.35526641 |
| 30 | SIK2 | 1.34410148 |
| 31 | PTK6 | 1.29099186 |
| 32 | YES1 | 1.22881964 |
| 33 | PRKD2 | 1.21554488 |
| 34 | LYN | 1.20878070 |
| 35 | IKBKE | 1.18546648 |
| 36 | MARK3 | 1.10232641 |
| 37 | MAP3K13 | 1.08475454 |
| 38 | LCK | 1.04725238 |
| 39 | TBK1 | 1.04274324 |
| 40 | CDK19 | 1.03796261 |
| 41 | STK38 | 1.03668360 |
| 42 | IRAK1 | 1.02175736 |
| 43 | MAP3K7 | 1.01048001 |
| 44 | SMG1 | 0.99815394 |
| 45 | CSF1R | 0.99447908 |
| 46 | MAP3K6 | 0.97773986 |
| 47 | PDK1 | 0.97665000 |
| 48 | SIK1 | 0.96902440 |
| 49 | PTK2B | 0.96882150 |
| 50 | MAP3K14 | 0.95426938 |
| 51 | JAK1 | 0.93563728 |
| 52 | TAOK3 | 0.93488384 |
| 53 | PDPK1 | 0.91334962 |
| 54 | IRAK2 | 0.88671199 |
| 55 | ITK | 0.82966622 |
| 56 | KIT | 0.82765213 |
| 57 | MAP3K2 | 0.81717678 |
| 58 | MATK | 0.79419080 |
| 59 | MAP2K4 | 0.76063626 |
| 60 | STK11 | 0.71690222 |
| 61 | TAOK2 | 0.71480785 |
| 62 | STK10 | 0.69445653 |
| 63 | CDC42BPA | 0.68338802 |
| 64 | DYRK1B | 0.67398887 |
| 65 | FYN | 0.66610692 |
| 66 | FGFR4 | 0.64178041 |
| 67 | TESK2 | 0.61349401 |
| 68 | TEC | 0.59191910 |
| 69 | RET | 0.58698079 |
| 70 | MAP2K6 | 0.58583758 |
| 71 | IKBKB | 0.58442437 |
| 72 | PRKG2 | 0.57599467 |
| 73 | EPHA3 | 0.53410712 |
| 74 | SGK3 | 0.52841194 |
| 75 | MAPK12 | 0.52629021 |
| 76 | LRRK2 | 0.52047151 |
| 77 | HIPK2 | 0.51763836 |
| 78 | RPS6KC1 | 0.51123805 |
| 79 | RPS6KL1 | 0.51123805 |
| 80 | PKN2 | 0.50369777 |
| 81 | CDK12 | 0.48270174 |
| 82 | BMX | 0.48182813 |
| 83 | PRKCZ | 0.46981602 |
| 84 | DAPK2 | 0.46890081 |
| 85 | WNK1 | 0.45643800 |
| 86 | FGFR3 | 0.44646683 |
| 87 | RPS6KA6 | 0.44354769 |
| 88 | RAF1 | 0.44335900 |
| 89 | KSR1 | 0.41716049 |
| 90 | MAPK7 | 0.41520620 |
| 91 | NLK | 0.41283945 |
| 92 | PRKCQ | 0.40521870 |
| 93 | MAP3K5 | 0.39688596 |
| 94 | BMPR2 | 0.36844493 |
| 95 | MAPKAPK2 | 0.36819019 |
| 96 | PIK3CG | 0.35884546 |
| 97 | RPS6KA1 | 0.34003521 |
| 98 | ALK | 0.32931382 |
| 99 | PRKCH | 0.32898520 |
| 100 | SGK2 | 0.32210612 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.15944808 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.88993044 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.67515828 |
| 4 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.40020290 |
| 5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.39154388 |
| 6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.26113756 |
| 7 | Tuberculosis_Homo sapiens_hsa05152 | 2.11126611 |
| 8 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.09039347 |
| 9 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.05681631 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.01944563 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 1.91330706 |
| 12 | Malaria_Homo sapiens_hsa05144 | 1.90118220 |
| 13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.90061587 |
| 14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.88753555 |
| 15 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.82900595 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.81894655 |
| 17 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.79730852 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.79197943 |
| 19 | Measles_Homo sapiens_hsa05162 | 1.71009730 |
| 20 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.55034030 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.51168091 |
| 22 | Legionellosis_Homo sapiens_hsa05134 | 1.44610451 |
| 23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.43795173 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.43527451 |
| 25 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.43447593 |
| 26 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.43285842 |
| 27 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.41728454 |
| 28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.41075091 |
| 29 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.39536964 |
| 30 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.38807729 |
| 31 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.34673404 |
| 32 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.34344758 |
| 33 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.33433660 |
| 34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.33017351 |
| 35 | Phagosome_Homo sapiens_hsa04145 | 1.28981716 |
| 36 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.28317913 |
| 37 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.26848170 |
| 38 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.21284115 |
| 39 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.20605129 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 1.16888536 |
| 41 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.08414069 |
| 42 | Hepatitis C_Homo sapiens_hsa05160 | 1.08159272 |
| 43 | Hepatitis B_Homo sapiens_hsa05161 | 1.08112002 |
| 44 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.04874368 |
| 45 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.03105073 |
| 46 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.01043892 |
| 47 | Endocytosis_Homo sapiens_hsa04144 | 0.96870998 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 0.92949099 |
| 49 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.91892627 |
| 50 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.90233979 |
| 51 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.89358203 |
| 52 | Salmonella infection_Homo sapiens_hsa05132 | 0.88078356 |
| 53 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.86944125 |
| 54 | Other glycan degradation_Homo sapiens_hsa00511 | 0.85027871 |
| 55 | Apoptosis_Homo sapiens_hsa04210 | 0.84542369 |
| 56 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.84327999 |
| 57 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.83745745 |
| 58 | Pertussis_Homo sapiens_hsa05133 | 0.82836628 |
| 59 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.80996810 |
| 60 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.80288909 |
| 61 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.80114758 |
| 62 | Endometrial cancer_Homo sapiens_hsa05213 | 0.78770727 |
| 63 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78142411 |
| 64 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77467018 |
| 65 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.76968858 |
| 66 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.75263922 |
| 67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.74709489 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73998363 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.73364989 |
| 70 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.72317613 |
| 71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.70871374 |
| 72 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.68006407 |
| 73 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.66889810 |
| 74 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.66859624 |
| 75 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.66676553 |
| 76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.66383061 |
| 77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.65868564 |
| 78 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64399932 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.63230522 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62411192 |
| 81 | Insulin resistance_Homo sapiens_hsa04931 | 0.62163108 |
| 82 | Colorectal cancer_Homo sapiens_hsa05210 | 0.61702903 |
| 83 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.61527551 |
| 84 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60456906 |
| 85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.59052495 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.58942225 |
| 87 | Amoebiasis_Homo sapiens_hsa05146 | 0.57619322 |
| 88 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.56959137 |
| 89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.56136069 |
| 90 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.55928253 |
| 91 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.52972302 |
| 92 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49606070 |
| 93 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.48713601 |
| 94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.47246132 |
| 95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46005487 |
| 96 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.45935442 |
| 97 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.41882068 |
| 98 | Prostate cancer_Homo sapiens_hsa05215 | 0.41166445 |
| 99 | Lysosome_Homo sapiens_hsa04142 | 0.40773032 |
| 100 | Asthma_Homo sapiens_hsa05310 | 0.39807236 |

