FAM166A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)8.19756160
2epithelial cilium movement (GO:0003351)7.96355877
3axonemal dynein complex assembly (GO:0070286)7.91810898
4viral transcription (GO:0019083)6.96201346
5translational termination (GO:0006415)6.72236290
6GTP biosynthetic process (GO:0006183)6.17892789
7ribosomal small subunit biogenesis (GO:0042274)6.16047108
8ribosomal large subunit biogenesis (GO:0042273)6.06875458
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.83284478
10cotranslational protein targeting to membrane (GO:0006613)5.80888442
11mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.77013348
12protein targeting to ER (GO:0045047)5.76225478
13establishment of protein localization to mitochondrial membrane (GO:0090151)5.72712527
14chaperone-mediated protein transport (GO:0072321)5.66913621
15establishment of protein localization to endoplasmic reticulum (GO:0072599)5.48156233
16translational elongation (GO:0006414)5.48065100
17cellular protein complex disassembly (GO:0043624)5.40667846
18protein localization to endoplasmic reticulum (GO:0070972)5.40234145
19energy coupled proton transport, down electrochemical gradient (GO:0015985)5.32498574
20ATP synthesis coupled proton transport (GO:0015986)5.32498574
21UTP biosynthetic process (GO:0006228)5.27728435
22viral life cycle (GO:0019058)5.19534167
23cilium or flagellum-dependent cell motility (GO:0001539)5.16826559
24motile cilium assembly (GO:0044458)5.05618048
25protein complex biogenesis (GO:0070271)5.02946446
26NADH dehydrogenase complex assembly (GO:0010257)4.98183296
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.98183296
28mitochondrial respiratory chain complex I assembly (GO:0032981)4.98183296
29nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.92089839
30mitochondrial respiratory chain complex assembly (GO:0033108)4.88381038
31ribosomal small subunit assembly (GO:0000028)4.81842156
32nucleoside diphosphate phosphorylation (GO:0006165)4.77221062
33axoneme assembly (GO:0035082)4.77171490
34protein neddylation (GO:0045116)4.76243279
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.74329526
36ventricular system development (GO:0021591)4.73760372
37translational initiation (GO:0006413)4.67437062
38water-soluble vitamin biosynthetic process (GO:0042364)4.64829287
39protein complex disassembly (GO:0043241)4.63205573
40maturation of SSU-rRNA (GO:0030490)4.52131630
41UTP metabolic process (GO:0046051)4.50967700
42macromolecular complex disassembly (GO:0032984)4.37749281
43regulation of mitochondrial translation (GO:0070129)4.37178553
44respiratory electron transport chain (GO:0022904)4.37119131
45guanosine-containing compound biosynthetic process (GO:1901070)4.33876002
46electron transport chain (GO:0022900)4.33233680
47sperm motility (GO:0030317)4.32232136
48behavioral response to nicotine (GO:0035095)4.23817468
49CTP metabolic process (GO:0046036)4.16363038
50CTP biosynthetic process (GO:0006241)4.16363038
51rRNA modification (GO:0000154)3.93161828
52microtubule depolymerization (GO:0007019)3.91948829
53acrosome reaction (GO:0007340)3.86510803
54DNA replication checkpoint (GO:0000076)3.84069407
55deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.80928916
56protein targeting to membrane (GO:0006612)3.79487198
57cell wall macromolecule catabolic process (GO:0016998)3.77888461
58cell wall macromolecule metabolic process (GO:0044036)3.77888461
59rRNA methylation (GO:0031167)3.72738625
60protein-cofactor linkage (GO:0018065)3.69521832
61male meiosis I (GO:0007141)3.67720253
62spermatid development (GO:0007286)3.64488582
63pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.63677829
64DNA deamination (GO:0045006)3.62156167
65interferon-gamma secretion (GO:0072643)3.59902552
66translation (GO:0006412)3.59146330
67acrosome assembly (GO:0001675)3.55725925
68pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.55010309
69fusion of sperm to egg plasma membrane (GO:0007342)3.53414579
70ribonucleoprotein complex biogenesis (GO:0022613)3.53278019
71sperm-egg recognition (GO:0035036)3.49266272
72transcription elongation from RNA polymerase III promoter (GO:0006385)3.44735122
73termination of RNA polymerase III transcription (GO:0006386)3.44735122
74glucosamine-containing compound catabolic process (GO:1901072)3.39480389
75short-term memory (GO:0007614)3.36476312
76exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36035328
77binding of sperm to zona pellucida (GO:0007339)3.33435117
78nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32933937
79pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.29572816
80keratinocyte proliferation (GO:0043616)3.28434878
81DNA ligation (GO:0006266)3.28323033
82regulation of cilium movement (GO:0003352)3.26517876
83desmosome organization (GO:0002934)3.25486245
84nuclear-transcribed mRNA catabolic process (GO:0000956)3.25235669
85protein targeting to mitochondrion (GO:0006626)3.22657482
86pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.16360440
87left/right pattern formation (GO:0060972)3.16039942
88meiotic cell cycle (GO:0051321)3.15097921
89keratinocyte development (GO:0003334)3.12983644
90intraciliary transport (GO:0042073)3.12561593
91pseudouridine synthesis (GO:0001522)3.10219676
92left/right axis specification (GO:0070986)3.09613720
93tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.09359218
94RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.09359218
95meiosis I (GO:0007127)3.08368302
96mRNA catabolic process (GO:0006402)3.08113489
97chromatin remodeling at centromere (GO:0031055)3.08027825
98establishment of protein localization to mitochondrion (GO:0072655)3.07600080
99DNA damage response, detection of DNA damage (GO:0042769)3.04563111
100protein K6-linked ubiquitination (GO:0085020)3.03347885
101protein localization to mitochondrion (GO:0070585)3.01895813
102embryonic body morphogenesis (GO:0010172)2.99038123
103CENP-A containing nucleosome assembly (GO:0034080)2.98779890
104intracellular protein transmembrane import (GO:0044743)2.98483118
105multicellular organism reproduction (GO:0032504)2.98062523
106nucleotide phosphorylation (GO:0046939)2.95258729
107proteasome assembly (GO:0043248)2.94533862
108cell-cell recognition (GO:0009988)2.93504233
109cytochrome complex assembly (GO:0017004)2.91785793
110cellular component biogenesis (GO:0044085)2.91304613
111kinetochore assembly (GO:0051382)2.89654777
112purine nucleoside triphosphate biosynthetic process (GO:0009145)2.88923923
113ATP biosynthetic process (GO:0006754)2.87291368
114negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.86544040
115cilium organization (GO:0044782)2.85469449
116purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.84349615
117RNA catabolic process (GO:0006401)2.82486263
118mitotic nuclear envelope reassembly (GO:0007084)2.82371675
119nuclear envelope reassembly (GO:0031468)2.82371675
120protein deneddylation (GO:0000338)2.81605701
121kinetochore organization (GO:0051383)2.81145672
122sphingoid metabolic process (GO:0046519)2.80917395
123regulation of protein kinase C signaling (GO:0090036)2.77860885
124cilium morphogenesis (GO:0060271)2.77520875
125intra-S DNA damage checkpoint (GO:0031573)2.76868207
126pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.76673939
127rRNA processing (GO:0006364)2.76384499
128negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.76328201
129pattern specification involved in kidney development (GO:0061004)2.76326300
130positive regulation of chemokine secretion (GO:0090197)2.76168028
131regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.75045793
132regulation of chemokine secretion (GO:0090196)2.74715996
133hydrogen ion transmembrane transport (GO:1902600)2.74420998
134rRNA metabolic process (GO:0016072)2.74404722
135respiratory chain complex IV assembly (GO:0008535)2.74180836
136cullin deneddylation (GO:0010388)2.73318831
137cilium assembly (GO:0042384)2.69030553
138histone exchange (GO:0043486)2.67837264
139ribonucleoside triphosphate biosynthetic process (GO:0009201)2.66978276
140negative regulation of T cell differentiation in thymus (GO:0033085)2.66568062
141tRNA processing (GO:0008033)2.65754615
142single fertilization (GO:0007338)2.65558386
143DNA catabolic process, exonucleolytic (GO:0000738)2.65026946
144protein targeting (GO:0006605)2.64173506
145establishment of protein localization to membrane (GO:0090150)2.62930833
146nucleoside diphosphate metabolic process (GO:0009132)2.61881482
147cardiovascular system development (GO:0072358)2.60744394
148spliceosomal snRNP assembly (GO:0000387)2.60321588
149mitochondrial transport (GO:0006839)2.58690786
150DNA replication-independent nucleosome assembly (GO:0006336)2.58690137
151DNA replication-independent nucleosome organization (GO:0034724)2.58690137
152mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.57234766
153mitochondrion morphogenesis (GO:0070584)2.56202980
154ncRNA processing (GO:0034470)2.50756774
155inner mitochondrial membrane organization (GO:0007007)2.49317625
156negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.48891726
157nucleoside triphosphate biosynthetic process (GO:0009142)2.48216174

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.10175997
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.75706122
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.53754204
4TP63_17297297_ChIP-ChIP_HaCaT_Human4.50022700
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.61528336
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.82461994
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.72087398
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.68495997
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.61232037
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.56275881
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.49222131
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.36478116
13EZH2_22144423_ChIP-Seq_EOC_Human2.22445164
14VDR_22108803_ChIP-Seq_LS180_Human2.18769921
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.15538269
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.14019921
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.11763921
18STAT6_21828071_ChIP-Seq_BEAS2B_Human2.10055926
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.06826890
20PCGF2_27294783_Chip-Seq_ESCs_Mouse1.99749956
21EST1_17652178_ChIP-ChIP_JURKAT_Human1.99400438
22NOTCH1_21737748_ChIP-Seq_TLL_Human1.96518668
23* TTF2_22483619_ChIP-Seq_HELA_Human1.96026286
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.95503866
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.92705597
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92306087
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.91796899
28FOXM1_23109430_ChIP-Seq_U2OS_Human1.90201397
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.89870380
30BMI1_23680149_ChIP-Seq_NPCS_Mouse1.85869348
31JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.80626470
32MYC_18358816_ChIP-ChIP_MESCs_Mouse1.80242853
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80114323
34TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73761806
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70805739
36EWS_26573619_Chip-Seq_HEK293_Human1.68514942
37E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.68502000
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.65280686
39DCP1A_22483619_ChIP-Seq_HELA_Human1.62735414
40ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.62599765
41RNF2_27304074_Chip-Seq_NSC_Mouse1.61338918
42NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.60917738
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.60316634
44NFE2_27457419_Chip-Seq_LIVER_Mouse1.56174991
45SUZ12_27294783_Chip-Seq_NPCs_Mouse1.51653437
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.50653467
47CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.49954883
48VDR_23849224_ChIP-Seq_CD4+_Human1.49824873
49* XRN2_22483619_ChIP-Seq_HELA_Human1.48841267
50* GABP_19822575_ChIP-Seq_HepG2_Human1.46177417
51MYC_19030024_ChIP-ChIP_MESCs_Mouse1.44340911
52E2F7_22180533_ChIP-Seq_HELA_Human1.42335028
53IRF1_19129219_ChIP-ChIP_H3396_Human1.41584050
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.36762988
55MYC_18940864_ChIP-ChIP_HL60_Human1.35339923
56TP63_19390658_ChIP-ChIP_HaCaT_Human1.34005771
57KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29763440
58KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.29628506
59KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.29628506
60KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.29628506
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28787222
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26632841
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26507607
64SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.25864413
65NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.25272168
66EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.24846218
67PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23291368
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19944167
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.19189388
70YY1_21170310_ChIP-Seq_MESCs_Mouse1.19083287
71FUS_26573619_Chip-Seq_HEK293_Human1.19039386
72GATA1_26923725_Chip-Seq_HPCs_Mouse1.18972788
73PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18351584
74P53_22387025_ChIP-Seq_ESCs_Mouse1.17086096
75FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15001932
76TAF15_26573619_Chip-Seq_HEK293_Human1.13731136
77EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.11377261
78P300_18555785_Chip-Seq_ESCs_Mouse1.11170623
79ELK1_19687146_ChIP-ChIP_HELA_Human1.10999956
80SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10016989
81ZFP57_27257070_Chip-Seq_ESCs_Mouse1.09831252
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.09367153
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08066376
84TAL1_26923725_Chip-Seq_HPCs_Mouse1.07684887
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.07569080
86CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07321239
87ZFX_18555785_Chip-Seq_ESCs_Mouse1.06191206
88EZH2_27294783_Chip-Seq_NPCs_Mouse1.06026325
89POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05931783
90SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05571255
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05076483
92FOXP3_21729870_ChIP-Seq_TREG_Human1.04758557
93MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04750314
94SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.04182975
95* TP53_22573176_ChIP-Seq_HFKS_Human1.03614155
96EED_16625203_ChIP-ChIP_MESCs_Mouse1.02996774
97OCT4_18555785_Chip-Seq_ESCs_Mouse1.02092191
98NMYC_18555785_Chip-Seq_ESCs_Mouse1.01688149
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00657479
100CRX_20693478_ChIP-Seq_RETINA_Mouse1.00561031
101AR_21909140_ChIP-Seq_LNCAP_Human1.00118565
102KLF4_18555785_Chip-Seq_ESCs_Mouse0.99094204
103PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98596149
104SOX2_18555785_Chip-Seq_ESCs_Mouse0.97418696
105RUNX1_27457419_Chip-Seq_LIVER_Mouse0.97213042
106GATA3_21878914_ChIP-Seq_MCF-7_Human0.96773491
107STAT3_18555785_Chip-Seq_ESCs_Mouse0.95446907
108SOX2_16153702_ChIP-ChIP_HESCs_Human0.95312790
109ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94926034
110E2F1_18555785_Chip-Seq_ESCs_Mouse0.94723544
111GATA3_21867929_ChIP-Seq_CD8_Mouse0.93204514
112TAF2_19829295_ChIP-Seq_ESCs_Human0.92925640
113* SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91317719
114YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91080162
115EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.90893574
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.90636314
117ESRRB_18555785_Chip-Seq_ESCs_Mouse0.90495513
118EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.90495351
119ZNF274_21170338_ChIP-Seq_K562_Hela0.90157122
120E2F1_18555785_ChIP-Seq_MESCs_Mouse0.89705836
121KDM5A_27292631_Chip-Seq_BREAST_Human0.89294408
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88709434
123RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.88431423
124FOXA1_25329375_ChIP-Seq_VCAP_Human0.87817095
125FOXA1_27270436_Chip-Seq_PROSTATE_Human0.87817095
126PU1_27457419_Chip-Seq_LIVER_Mouse0.86036518
127NCOR_22424771_ChIP-Seq_293T_Human0.85140770
128POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.84836145
129PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.84815850
130POU3F2_20337985_ChIP-ChIP_501MEL_Human0.84811579
131* FOXP1_21924763_ChIP-Seq_HESCs_Human0.84294165
132CTCF_18555785_ChIP-Seq_MESCs_Mouse0.84244349
133CMYC_18555785_Chip-Seq_ESCs_Mouse0.83908047
134NANOG_20526341_ChIP-Seq_ESCs_Human0.83784381
135EZH2_27304074_Chip-Seq_ESCs_Mouse0.82966089
136TDRD3_21172665_ChIP-Seq_MCF-7_Human0.82782770
137AUTS2_25519132_ChIP-Seq_293T-REX_Human0.81344796
138HOXB4_20404135_ChIP-ChIP_EML_Mouse0.81244968
139ERA_21632823_ChIP-Seq_H3396_Human0.80707489
140ERG_20517297_ChIP-Seq_VCAP_Human0.80045500
141CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.79828698
142AR_20517297_ChIP-Seq_VCAP_Human0.79538637
143HTT_18923047_ChIP-ChIP_STHdh_Human0.79507665
144* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.79039591
145NANOG_19829295_ChIP-Seq_ESCs_Human0.77876264
146SOX2_19829295_ChIP-Seq_ESCs_Human0.77876264
147NELFA_20434984_ChIP-Seq_ESCs_Mouse0.77560164

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.44450359
2MP0003136_yellow_coat_color5.81126268
3MP0004381_abnormal_hair_follicle4.32986298
4MP0005410_abnormal_fertilization3.90403364
5MP0003941_abnormal_skin_development3.64617326
6MP0001188_hyperpigmentation3.09739846
7MP0002796_impaired_skin_barrier2.55279410
8MP0000566_synostosis2.53584181
9MP0001485_abnormal_pinna_reflex2.24796082
10MP0002102_abnormal_ear_morphology2.07569327
11MP0002837_dystrophic_cardiac_calcinosis1.91431465
12MP0008932_abnormal_embryonic_tissue1.86334056
13MP0003698_abnormal_male_reproductive1.85521606
14MP0005501_abnormal_skin_physiology1.84398137
15MP0006276_abnormal_autonomic_nervous1.83006583
16MP0010030_abnormal_orbit_morphology1.80262114
17MP0005646_abnormal_pituitary_gland1.78618574
18MP0001929_abnormal_gametogenesis1.74050646
19MP0003938_abnormal_ear_development1.72436711
20MP0002876_abnormal_thyroid_physiology1.70759385
21MP0001986_abnormal_taste_sensitivity1.69883462
22MP0003880_abnormal_central_pattern1.69672473
23MP0003693_abnormal_embryo_hatching1.65802552
24MP0008004_abnormal_stomach_pH1.65378368
25MP0001293_anophthalmia1.64849432
26MP0003724_increased_susceptibility_to1.61679872
27MP0002277_abnormal_respiratory_mucosa1.61344630
28MP0002210_abnormal_sex_determination1.60494354
29MP0006292_abnormal_olfactory_placode1.51548708
30MP0002160_abnormal_reproductive_system1.50236393
31MP0001905_abnormal_dopamine_level1.49163657
32MP0009250_abnormal_appendicular_skeleto1.48009614
33MP0000049_abnormal_middle_ear1.46785468
34MP0003186_abnormal_redox_activity1.46744846
35MP0009046_muscle_twitch1.45791543
36MP0003315_abnormal_perineum_morphology1.42808729
37MP0003786_premature_aging1.39842959
38MP0003283_abnormal_digestive_organ1.39792009
39MP0005377_hearing/vestibular/ear_phenot1.37558145
40MP0003878_abnormal_ear_physiology1.37558145
41MP0004885_abnormal_endolymph1.36909744
42MP0006036_abnormal_mitochondrial_physio1.35967403
43MP0003806_abnormal_nucleotide_metabolis1.35229088
44MP0008875_abnormal_xenobiotic_pharmacok1.34081549
45MP0003123_paternal_imprinting1.33044591
46MP0000467_abnormal_esophagus_morphology1.33042523
47MP0002249_abnormal_larynx_morphology1.32944524
48MP0001919_abnormal_reproductive_system1.32419454
49MP0000762_abnormal_tongue_morphology1.31970970
50MP0002095_abnormal_skin_pigmentation1.31944834
51MP0005551_abnormal_eye_electrophysiolog1.30221873
52MP0002163_abnormal_gland_morphology1.29823338
53MP0005174_abnormal_tail_pigmentation1.29674802
54MP0001346_abnormal_lacrimal_gland1.29651939
55MP0005409_darkened_coat_color1.29119235
56MP0010771_integument_phenotype1.26860948
57MP0002653_abnormal_ependyma_morphology1.26248688
58MP0002098_abnormal_vibrissa_morphology1.26000028
59MP0002177_abnormal_outer_ear1.22317951
60MP0005075_abnormal_melanosome_morpholog1.22306786
61MP0008877_abnormal_DNA_methylation1.21778134
62MP0002272_abnormal_nervous_system1.21766311
63MP0008872_abnormal_physiological_respon1.21189370
64MP0000647_abnormal_sebaceous_gland1.19725974
65MP0001145_abnormal_male_reproductive1.18606505
66MP0004957_abnormal_blastocyst_morpholog1.18209259
67MP0002132_abnormal_respiratory_system1.17643807
68MP0002009_preneoplasia1.15233742
69MP0003122_maternal_imprinting1.13658294
70MP0005389_reproductive_system_phenotype1.12061391
71MP0003303_peritoneal_inflammation1.11417450
72MP0003119_abnormal_digestive_system1.09680002
73MP0003195_calcinosis1.09000584
74MP0004043_abnormal_pH_regulation1.08745071
75MP0003111_abnormal_nucleus_morphology1.08390596
76MP0009745_abnormal_behavioral_response1.07487983
77MP0000653_abnormal_sex_gland1.07172203
78MP0001968_abnormal_touch/_nociception1.07028968
79MP0005423_abnormal_somatic_nervous1.06448403
80MP0010094_abnormal_chromosome_stability1.03675877
81MP0003121_genomic_imprinting1.01020500
82MP0001216_abnormal_epidermal_layer1.00669978
83MP0000377_abnormal_hair_follicle1.00288553
84MP0000383_abnormal_hair_follicle0.99468257
85MP0002060_abnormal_skin_morphology0.99229492
86MP0002282_abnormal_trachea_morphology0.97323144
87MP0004019_abnormal_vitamin_homeostasis0.97255679
88MP0002736_abnormal_nociception_after0.94491224
89MP0002638_abnormal_pupillary_reflex0.94437244
90MP0003718_maternal_effect0.94274813
91MP0008058_abnormal_DNA_repair0.94097895
92MP0005332_abnormal_amino_acid0.93673066
93MP0002138_abnormal_hepatobiliary_system0.93548454
94MP0001542_abnormal_bone_strength0.93300480
95MP0004142_abnormal_muscle_tone0.92031654
96MP0003011_delayed_dark_adaptation0.91150760
97MP0004145_abnormal_muscle_electrophysio0.90397341
98MP0005195_abnormal_posterior_eye0.89876209
99MP0005253_abnormal_eye_physiology0.88730142
100MP0003755_abnormal_palate_morphology0.87583074
101MP0000372_irregular_coat_pigmentation0.86512088
102MP0000026_abnormal_inner_ear0.86211447
103MP0003937_abnormal_limbs/digits/tail_de0.86037137
104MP0003453_abnormal_keratinocyte_physiol0.85294446
105MP0002161_abnormal_fertility/fecundity0.85031570
106MP0003567_abnormal_fetal_cardiomyocyte0.84486486
107MP0003942_abnormal_urinary_system0.83740731
108MP0001529_abnormal_vocalization0.83415051
109MP0005257_abnormal_intraocular_pressure0.83052593
110MP0003879_abnormal_hair_cell0.82718342
111MP0000613_abnormal_salivary_gland0.82655837
112MP0005379_endocrine/exocrine_gland_phen0.81646896
113MP0008007_abnormal_cellular_replicative0.80767019
114MP0002557_abnormal_social/conspecific_i0.80219535
115MP0001340_abnormal_eyelid_morphology0.78317028
116MP0001756_abnormal_urination0.78206948
117MP0003077_abnormal_cell_cycle0.77975327
118MP0002938_white_spotting0.77493022
119MP0001502_abnormal_circadian_rhythm0.76239446
120MP0002751_abnormal_autonomic_nervous0.76108430
121MP0001944_abnormal_pancreas_morphology0.75450516
122MP0005645_abnormal_hypothalamus_physiol0.74436152
123MP0000579_abnormal_nail_morphology0.74263600
124MP0000631_abnormal_neuroendocrine_gland0.71684942
125MP0008789_abnormal_olfactory_epithelium0.70536490
126MP0006072_abnormal_retinal_apoptosis0.69248239
127MP0001501_abnormal_sleep_pattern0.69214771
128MP0003385_abnormal_body_wall0.69179577
129MP0000778_abnormal_nervous_system0.69055560
130MP0004742_abnormal_vestibular_system0.67831097
131MP0004133_heterotaxia0.66534458
132MP0000427_abnormal_hair_cycle0.65652631
133MP0005623_abnormal_meninges_morphology0.65297875
134MP0003646_muscle_fatigue0.64750517
135MP0001286_abnormal_eye_development0.64309309
136MP0002234_abnormal_pharynx_morphology0.64206762
137MP0003936_abnormal_reproductive_system0.62573371
138MP0005084_abnormal_gallbladder_morpholo0.59473511
139MP0009697_abnormal_copulation0.58914221
140MP0003828_pulmonary_edema0.58288291
141MP0005397_hematopoietic_system_phenotyp0.57795275
142MP0001545_abnormal_hematopoietic_system0.57795275

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.91011374
2Abnormal respiratory motile cilium physiology (HP:0012261)7.65739010
3Abnormal ciliary motility (HP:0012262)7.62684187
4Dynein arm defect of respiratory motile cilia (HP:0012255)6.10190467
5Absent/shortened dynein arms (HP:0200106)6.10190467
6Abnormal respiratory motile cilium morphology (HP:0005938)5.92601322
7Abnormal respiratory epithelium morphology (HP:0012253)5.92601322
8Rhinitis (HP:0012384)5.26271928
9Abnormal mitochondria in muscle tissue (HP:0008316)4.41160965
10Chronic bronchitis (HP:0004469)4.39130424
11Reticulocytopenia (HP:0001896)4.26521545
12Acute encephalopathy (HP:0006846)4.08822390
133-Methylglutaconic aciduria (HP:0003535)3.79193238
14Increased CSF lactate (HP:0002490)3.70710634
15Aplasia/Hypoplasia of the sacrum (HP:0008517)3.66486186
16Concave nail (HP:0001598)3.61201957
17Abnormal hemoglobin (HP:0011902)3.43767325
18Bronchiectasis (HP:0002110)3.39184556
19Macrocytic anemia (HP:0001972)3.31141210
20True hermaphroditism (HP:0010459)3.15384370
21Nasal polyposis (HP:0100582)3.13247936
22Hepatic necrosis (HP:0002605)2.96452888
23Abnormality of cells of the erythroid lineage (HP:0012130)2.93444549
24Cerebral edema (HP:0002181)2.93014754
25Parakeratosis (HP:0001036)2.81857101
26Infertility (HP:0000789)2.78653079
27Pallor (HP:0000980)2.78609195
28Sparse lateral eyebrow (HP:0005338)2.77361624
29Abnormal number of erythroid precursors (HP:0012131)2.76950398
30Down-sloping shoulders (HP:0200021)2.76630123
31Methylmalonic acidemia (HP:0002912)2.75503006
32Abnormality of renal resorption (HP:0011038)2.70625906
33Methylmalonic aciduria (HP:0012120)2.58829785
34Pendular nystagmus (HP:0012043)2.58353389
35Pancreatic fibrosis (HP:0100732)2.55456911
36Abnormality of the nasal mucosa (HP:0000433)2.50619836
37Abnormality of alanine metabolism (HP:0010916)2.49760307
38Hyperalaninemia (HP:0003348)2.49760307
39Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.49760307
40Supernumerary spleens (HP:0009799)2.49297664
41Pancreatic cysts (HP:0001737)2.46647880
42Rib fusion (HP:0000902)2.45555663
43Congenital, generalized hypertrichosis (HP:0004540)2.42408331
44Increased intramyocellular lipid droplets (HP:0012240)2.39781020
45Increased serum lactate (HP:0002151)2.39140406
46Hypoparathyroidism (HP:0000829)2.38490142
47Abdominal situs inversus (HP:0003363)2.37481154
48Abnormality of abdominal situs (HP:0011620)2.37481154
49Sparse eyelashes (HP:0000653)2.36359096
50Abnormality of urine glucose concentration (HP:0011016)2.35092420
51Glycosuria (HP:0003076)2.35092420
52Abnormal pupillary function (HP:0007686)2.33846187
53Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.30622314
54Anhidrosis (HP:0000970)2.27785019
55Lactic acidosis (HP:0003128)2.26571043
56Triphalangeal thumb (HP:0001199)2.26260866
57Exercise intolerance (HP:0003546)2.24297328
58Respiratory failure (HP:0002878)2.22451964
59Hypothermia (HP:0002045)2.20133146
60Congenital sensorineural hearing impairment (HP:0008527)2.17683548
61Recurrent sinusitis (HP:0011108)2.13755023
62Aplasia/Hypoplasia of the patella (HP:0006498)2.13706788
63Mitochondrial inheritance (HP:0001427)2.13279829
64Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.12948812
65Increased hepatocellular lipid droplets (HP:0006565)2.12930521
66Molar tooth sign on MRI (HP:0002419)2.12700825
67Abnormality of midbrain morphology (HP:0002418)2.12700825
68Congenital stationary night blindness (HP:0007642)2.11994048
69Sex reversal (HP:0012245)2.11906737
70Abnormal sex determination (HP:0012244)2.11906737
71Aplasia/Hypoplasia of the tongue (HP:0010295)2.10839960
72Nephronophthisis (HP:0000090)2.10625777
73Aplasia/hypoplasia of the uterus (HP:0008684)2.10189042
74Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.09563760
75Respiratory difficulties (HP:0002880)2.04740890
76Lethargy (HP:0001254)2.04085562
77Bronchitis (HP:0012387)2.03478270
78Abnormality of the phalanges of the 2nd finger (HP:0009541)2.02784497
79Dry hair (HP:0011359)2.01072342
80Leukodystrophy (HP:0002415)2.01032786
81Obstructive sleep apnea (HP:0002870)1.99345268
82Breast hypoplasia (HP:0003187)1.98691443
83Abnormal number of incisors (HP:0011064)1.97549600
84Seborrheic dermatitis (HP:0001051)1.97282993
8511 pairs of ribs (HP:0000878)1.96625222
86Hypoplasia of the pons (HP:0012110)1.96560299
87Increased muscle lipid content (HP:0009058)1.96468519
88Tubulointerstitial nephritis (HP:0001970)1.96209379
89Optic disc pallor (HP:0000543)1.95313679
90Acute necrotizing encephalopathy (HP:0006965)1.93063240
91Medial flaring of the eyebrow (HP:0010747)1.91966597
92Abnormality of the preputium (HP:0100587)1.90363452
93Upper limb muscle weakness (HP:0003484)1.90298908
94Fragile nails (HP:0001808)1.89769528
95Anophthalmia (HP:0000528)1.89579131
96Stenosis of the external auditory canal (HP:0000402)1.89320522
97Absent thumb (HP:0009777)1.89173754
98Abnormality of the pons (HP:0007361)1.89104271
99Maternal diabetes (HP:0009800)1.88452978
100Colon cancer (HP:0003003)1.87781801
101Short tibia (HP:0005736)1.87190860
102Microglossia (HP:0000171)1.86805911
103Hypochromic anemia (HP:0001931)1.86219353
104Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.86125690
105Hyperglycinemia (HP:0002154)1.85743793
106Abnormal drinking behavior (HP:0030082)1.85738495
107Polydipsia (HP:0001959)1.85738495
108Hypoplastic pelvis (HP:0008839)1.85593854
109Abnormal rod and cone electroretinograms (HP:0008323)1.85295903
110Ridged nail (HP:0001807)1.85267612
111Anencephaly (HP:0002323)1.84615317
112Exertional dyspnea (HP:0002875)1.82090117
113Chronic obstructive pulmonary disease (HP:0006510)1.81969480
114Obstructive lung disease (HP:0006536)1.81969480
115Secondary amenorrhea (HP:0000869)1.81197877
116Hepatocellular necrosis (HP:0001404)1.81145743
117Depressed nasal ridge (HP:0000457)1.80749029
118Abnormality of dental color (HP:0011073)1.79931881
119Aplasia/Hypoplasia of the tibia (HP:0005772)1.79593447
120Patellar aplasia (HP:0006443)1.79552699
121Abnormality of the middle phalanges of the toes (HP:0010183)1.78430817
122Small hand (HP:0200055)1.77849455
123Abnormality of the renal collecting system (HP:0004742)1.76920277
124Ectopic kidney (HP:0000086)1.76451927
125Septo-optic dysplasia (HP:0100842)1.76396940
126Abnormality of the renal medulla (HP:0100957)1.75830002
127Horseshoe kidney (HP:0000085)1.75189281
128Hypotrichosis (HP:0001006)1.74764319
129Optic nerve hypoplasia (HP:0000609)1.73310667
130Median cleft lip (HP:0000161)1.73282970
131Microretrognathia (HP:0000308)1.73140312
132Symphalangism affecting the phalanges of the hand (HP:0009773)1.72652645
133Male pseudohermaphroditism (HP:0000037)1.72578921
134Birth length less than 3rd percentile (HP:0003561)1.71944960
135Myokymia (HP:0002411)1.71890518
136Hypoplasia of the radius (HP:0002984)1.71846976
137Woolly hair (HP:0002224)1.71537399
138Testicular atrophy (HP:0000029)1.71480222
139Fibular aplasia (HP:0002990)1.71370024
140Confusion (HP:0001289)1.71339534
141Abnormality of serum amino acid levels (HP:0003112)1.69664970
142Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.69287972
143Renal Fanconi syndrome (HP:0001994)1.68600034
144Sclerocornea (HP:0000647)1.68349864
145Hyperthyroidism (HP:0000836)1.66898494
146Natal tooth (HP:0000695)1.66815226
147Lip pit (HP:0100267)1.66767475
148Abnormality of the axillary hair (HP:0100134)1.66480495
149Abnormality of secondary sexual hair (HP:0009888)1.66480495
150Abnormality of the septum pellucidum (HP:0007375)1.65984262
151Lipid accumulation in hepatocytes (HP:0006561)1.65077562
152Premature rupture of membranes (HP:0001788)1.65058811
153Progressive macrocephaly (HP:0004481)1.63926882
154Decreased activity of mitochondrial respiratory chain (HP:0008972)1.63595357
155Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.63595357
156Atelectasis (HP:0100750)1.63219366
157Preaxial hand polydactyly (HP:0001177)1.62071716
158Absent rod-and cone-mediated responses on ERG (HP:0007688)1.62029079

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK15.66355372
2EIF2AK14.13731359
3NME23.18019644
4CASK3.16667073
5BUB13.12462317
6WEE13.00818272
7MKNK22.54838687
8PBK2.45540561
9NEK12.31675511
10VRK22.30054205
11MAPK152.19675882
12STK162.18170600
13PNCK2.15936505
14IRAK12.11187674
15SRPK12.02685484
16VRK11.92256388
17MST41.81482969
18TESK11.76274852
19DYRK31.75071311
20MKNK11.74690217
21ADRBK21.72379989
22FRK1.72144676
23WNK31.50786956
24CDK81.48857757
25NUAK11.45556253
26PIM21.44827556
27TESK21.42211543
28TNIK1.41622172
29CDK191.40278578
30FER1.38542386
31FES1.36353050
32AURKA1.33468334
33PHKG21.31926462
34PHKG11.31926462
35NME11.31755516
36IRAK31.31236642
37NEK91.29058907
38EIF2AK21.28066689
39CLK11.27518881
40STK391.24020066
41NLK1.20457288
42PDK31.17267361
43PDK41.17267361
44ABL21.14783642
45RPS6KA51.11653707
46TTK1.10738086
47BLK1.09143437
48MAPKAPK51.06885647
49IRAK21.05305160
50MAP4K21.04162764
51BMPR1B1.03415956
52BCKDK1.02642007
53RPS6KA41.02160405
54CCNB10.99016985
55DYRK1B0.98632836
56PLK20.97672040
57EIF2AK30.96450446
58PLK10.94454017
59PASK0.94106762
60PINK10.93774572
61INSRR0.91924831
62MAP3K110.88189020
63TAF10.80602856
64DYRK20.77217345
65DMPK0.75322129
66TEC0.74836779
67MAP2K70.73703400
68AURKB0.72255125
69IRAK40.71833743
70MAPKAPK30.71611015
71STK240.70707413
72GRK70.69753206
73PLK40.68378339
74EPHB20.68348109
75CDK90.67999073
76MYLK0.67849518
77MINK10.65689578
78CDK30.64853679
79MAP3K120.64731726
80WNK40.63482885
81PDK20.62240892
82BRSK20.61711516
83ZAK0.59614252
84YES10.59325074
85NEK20.57034904
86TSSK60.54856266
87CDK70.54409910
88PLK30.54376251
89TGFBR10.54227762
90MAP2K60.52753463
91STK30.51271397
92TRIM280.51001196
93ATR0.50680777
94CSNK2A10.50651613
95CSNK2A20.48359493
96BRAF0.46981211
97GRK10.45962686
98ILK0.45767186
99TAOK30.45502105
100STK110.45359063
101PRKCI0.44698425
102PRKACA0.44259933
103CHEK20.43431530
104CSNK1E0.43256248
105CSNK1A10.42726653
106DYRK1A0.42410327
107IKBKB0.42074155
108ADRBK10.41684372
109PRPF4B0.41368514
110CAMK2A0.40198925
111MUSK0.40072090
112CSNK1G20.39244987
113BCR0.39239044
114UHMK10.38850483
115CSNK1G10.38459778
116STK40.37848678
117LIMK10.37667853
118GRK50.37617127
119MAPK40.36217921
120MAP2K20.35158823
121TXK0.34914798
122BRSK10.34736051
123CDK140.34541968
124PRKCE0.34363925
125DAPK30.34348332
126BMPR20.34036963
127ACVR1B0.33554975
128HIPK20.33382989
129PRKG10.32783551
130CSNK1G30.32179580
131MST1R0.32169602
132PAK10.31785368
133STK38L0.31718125
134CDC70.30717107
135TIE10.27645960
136OXSR10.25108911
137RPS6KA60.25034012
138CHEK10.24880089
139PRKCA0.24345753
140ATM0.24258915
141ERBB20.23142645
142CAMK10.22414778
143WNK10.21430310
144PRKCG0.20790231

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.63464388
2RNA polymerase_Homo sapiens_hsa030203.05283935
3Protein export_Homo sapiens_hsa030602.95061299
4Oxidative phosphorylation_Homo sapiens_hsa001902.87585866
5DNA replication_Homo sapiens_hsa030302.66262823
6Homologous recombination_Homo sapiens_hsa034402.50034337
7Huntingtons disease_Homo sapiens_hsa050162.37785022
8Fanconi anemia pathway_Homo sapiens_hsa034602.36368581
9Spliceosome_Homo sapiens_hsa030402.28500524
10Pyrimidine metabolism_Homo sapiens_hsa002402.27758998
11Parkinsons disease_Homo sapiens_hsa050122.26688153
12Basal transcription factors_Homo sapiens_hsa030222.19898170
13Mismatch repair_Homo sapiens_hsa034302.18564868
14Nucleotide excision repair_Homo sapiens_hsa034202.10322038
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.99215298
16Sulfur relay system_Homo sapiens_hsa041221.94801242
17Proteasome_Homo sapiens_hsa030501.88851959
18Alzheimers disease_Homo sapiens_hsa050101.68735457
19Sphingolipid metabolism_Homo sapiens_hsa006001.51954076
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.51595247
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.49063810
22Base excision repair_Homo sapiens_hsa034101.41558377
23Arachidonic acid metabolism_Homo sapiens_hsa005901.38282461
24Purine metabolism_Homo sapiens_hsa002301.37418513
25Cell cycle_Homo sapiens_hsa041101.33721138
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.33514774
27RNA transport_Homo sapiens_hsa030131.30858387
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.30057783
29Linoleic acid metabolism_Homo sapiens_hsa005911.22987619
30Phototransduction_Homo sapiens_hsa047441.11042782
31Ether lipid metabolism_Homo sapiens_hsa005651.10968221
32p53 signaling pathway_Homo sapiens_hsa041151.09254201
33Vitamin B6 metabolism_Homo sapiens_hsa007501.06015335
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03414068
35Basal cell carcinoma_Homo sapiens_hsa052171.01343146
36Hedgehog signaling pathway_Homo sapiens_hsa043401.00636809
37Sulfur metabolism_Homo sapiens_hsa009200.99587195
38Cardiac muscle contraction_Homo sapiens_hsa042600.97500362
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.90077998
40Systemic lupus erythematosus_Homo sapiens_hsa053220.88824330
41mRNA surveillance pathway_Homo sapiens_hsa030150.88567343
42One carbon pool by folate_Homo sapiens_hsa006700.87991241
43Folate biosynthesis_Homo sapiens_hsa007900.86666237
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85440329
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85366899
46Alcoholism_Homo sapiens_hsa050340.84598165
47Selenocompound metabolism_Homo sapiens_hsa004500.83324297
48Wnt signaling pathway_Homo sapiens_hsa043100.79129862
49Oocyte meiosis_Homo sapiens_hsa041140.78908339
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.77873234
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.76498675
52Chemical carcinogenesis_Homo sapiens_hsa052040.76229795
53RNA degradation_Homo sapiens_hsa030180.72241070
54Epstein-Barr virus infection_Homo sapiens_hsa051690.72159407
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.71807392
56Serotonergic synapse_Homo sapiens_hsa047260.70940350
57Nitrogen metabolism_Homo sapiens_hsa009100.68803110
58Vitamin digestion and absorption_Homo sapiens_hsa049770.66257473
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65312590
60Tryptophan metabolism_Homo sapiens_hsa003800.64053456
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62637168
62Amphetamine addiction_Homo sapiens_hsa050310.62528077
63Drug metabolism - other enzymes_Homo sapiens_hsa009830.62493390
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61494874
65Pyruvate metabolism_Homo sapiens_hsa006200.61196111
66Glutathione metabolism_Homo sapiens_hsa004800.61145869
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60096030
68Caffeine metabolism_Homo sapiens_hsa002320.59983934
69Hematopoietic cell lineage_Homo sapiens_hsa046400.57650345
70Non-homologous end-joining_Homo sapiens_hsa034500.56292161
71Nicotine addiction_Homo sapiens_hsa050330.55114942
72Pentose and glucuronate interconversions_Homo sapiens_hsa000400.54211090
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53662677
74Peroxisome_Homo sapiens_hsa041460.53361919
75Butanoate metabolism_Homo sapiens_hsa006500.52590464
76Collecting duct acid secretion_Homo sapiens_hsa049660.52249375
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51329021
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51169100
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.49977782
80Morphine addiction_Homo sapiens_hsa050320.49232317
81Retinol metabolism_Homo sapiens_hsa008300.48405924
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.48264827
83Maturity onset diabetes of the young_Homo sapiens_hsa049500.47372426
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.46398123
85Steroid biosynthesis_Homo sapiens_hsa001000.46295615
86Histidine metabolism_Homo sapiens_hsa003400.45613841
87Metabolic pathways_Homo sapiens_hsa011000.45203305
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45152922
89Melanogenesis_Homo sapiens_hsa049160.44931981
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43920317
91Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42782480
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42376276
93Herpes simplex infection_Homo sapiens_hsa051680.41607459
94Regulation of autophagy_Homo sapiens_hsa041400.41414317
95Cocaine addiction_Homo sapiens_hsa050300.41067069
96beta-Alanine metabolism_Homo sapiens_hsa004100.39031252
97Fatty acid elongation_Homo sapiens_hsa000620.37114362
98Bladder cancer_Homo sapiens_hsa052190.36838588
99Fat digestion and absorption_Homo sapiens_hsa049750.36287525
100Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35083419
101Olfactory transduction_Homo sapiens_hsa047400.34869223
102Vibrio cholerae infection_Homo sapiens_hsa051100.33949672
103Dorso-ventral axis formation_Homo sapiens_hsa043200.33753856
104Melanoma_Homo sapiens_hsa052180.33004988
105Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.32653016
106Long-term depression_Homo sapiens_hsa047300.32245757
107Fatty acid degradation_Homo sapiens_hsa000710.31716890
108Glycerolipid metabolism_Homo sapiens_hsa005610.31017766
109Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.30898559
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29937745
111Propanoate metabolism_Homo sapiens_hsa006400.29623444
112Taste transduction_Homo sapiens_hsa047420.29596182
113Thyroid cancer_Homo sapiens_hsa052160.29293518
114Mineral absorption_Homo sapiens_hsa049780.29286984
115Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.28500716
116Insulin secretion_Homo sapiens_hsa049110.28171379
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27770601
118Hippo signaling pathway_Homo sapiens_hsa043900.27752001
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.25582399
120Other glycan degradation_Homo sapiens_hsa005110.25508846
121Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25394519
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.22512582
123Tight junction_Homo sapiens_hsa045300.21212171
124Tyrosine metabolism_Homo sapiens_hsa003500.20230899
125HTLV-I infection_Homo sapiens_hsa051660.19778784
126Autoimmune thyroid disease_Homo sapiens_hsa053200.18517400
127Ras signaling pathway_Homo sapiens_hsa040140.17393928
128TGF-beta signaling pathway_Homo sapiens_hsa043500.16775994
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.15941585
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.15923022
131Pathways in cancer_Homo sapiens_hsa052000.15760864
132Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.15748095
133Steroid hormone biosynthesis_Homo sapiens_hsa001400.15498986

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »