FAM168A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.06819931
2axon ensheathment in central nervous system (GO:0032291)5.06819931
3neuron cell-cell adhesion (GO:0007158)4.84260188
4synaptic vesicle maturation (GO:0016188)4.73063672
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.70121126
6sodium ion export (GO:0071436)4.65836517
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.55542450
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.46258012
9vocalization behavior (GO:0071625)4.45689810
10locomotory exploration behavior (GO:0035641)4.37697222
11synaptic vesicle exocytosis (GO:0016079)4.32933932
12dendritic spine morphogenesis (GO:0060997)4.29591549
13glutamate secretion (GO:0014047)4.29010667
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.23964654
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.18196415
16neuronal action potential propagation (GO:0019227)4.09681819
17regulation of synaptic vesicle exocytosis (GO:2000300)4.05665613
18neuron recognition (GO:0008038)3.91137218
19protein localization to synapse (GO:0035418)3.88501494
20presynaptic membrane assembly (GO:0097105)3.85372912
21presynaptic membrane organization (GO:0097090)3.84376584
22regulation of glutamate receptor signaling pathway (GO:1900449)3.83293771
23glutamate receptor signaling pathway (GO:0007215)3.79819865
24cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.78660880
25gamma-aminobutyric acid transport (GO:0015812)3.76524959
26layer formation in cerebral cortex (GO:0021819)3.73563405
27regulation of neuronal synaptic plasticity (GO:0048168)3.69240451
28synaptic transmission, glutamatergic (GO:0035249)3.65681954
29transmission of nerve impulse (GO:0019226)3.65106362
30regulation of ARF protein signal transduction (GO:0032012)3.62492049
31regulation of long-term neuronal synaptic plasticity (GO:0048169)3.61094595
32neuron-neuron synaptic transmission (GO:0007270)3.59024711
33positive regulation of synapse maturation (GO:0090129)3.58576425
34axonal fasciculation (GO:0007413)3.58118338
35L-amino acid import (GO:0043092)3.53491133
36cell communication by electrical coupling (GO:0010644)3.53264719
37exploration behavior (GO:0035640)3.52927143
38regulation of synaptic vesicle transport (GO:1902803)3.50066928
39negative regulation of neurotransmitter transport (GO:0051589)3.49539994
40cytoskeletal anchoring at plasma membrane (GO:0007016)3.44575336
41cerebellar granule cell differentiation (GO:0021707)3.42377334
42dendrite morphogenesis (GO:0048813)3.39352042
43neurotransmitter secretion (GO:0007269)3.39032809
44regulation of synapse structural plasticity (GO:0051823)3.32957682
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.32170347
46potassium ion homeostasis (GO:0055075)3.31421759
47establishment of mitochondrion localization (GO:0051654)3.30668007
48regulation of dendritic spine morphogenesis (GO:0061001)3.27536264
49long-chain fatty acid biosynthetic process (GO:0042759)3.26858648
50long-term memory (GO:0007616)3.26716401
51membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.26070321
52neurotransmitter-gated ion channel clustering (GO:0072578)3.26049280
53adult walking behavior (GO:0007628)3.25367837
54neuronal ion channel clustering (GO:0045161)3.24734132
55regulation of excitatory postsynaptic membrane potential (GO:0060079)3.23319312
56negative regulation of synaptic transmission, GABAergic (GO:0032229)3.22821705
57regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.22309200
58myelination (GO:0042552)3.20667175
59regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.19874260
60synaptic vesicle docking involved in exocytosis (GO:0016081)3.16738614
61axon ensheathment (GO:0008366)3.16205104
62ensheathment of neurons (GO:0007272)3.16205104
63potassium ion import (GO:0010107)3.14743314
64regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.10843953
65positive regulation of membrane potential (GO:0045838)3.09953839
66regulation of postsynaptic membrane potential (GO:0060078)3.07858129
67mating behavior (GO:0007617)3.05363407
68G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05020460
69cellular potassium ion homeostasis (GO:0030007)3.04147284
70positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.03333040
71positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.01423228
72neurotransmitter transport (GO:0006836)3.00809125
73long-term synaptic potentiation (GO:0060291)3.00567174
74regulation of synaptic plasticity (GO:0048167)2.99472822
75postsynaptic membrane organization (GO:0001941)2.99078087
76negative regulation of neurotransmitter secretion (GO:0046929)2.98925853
77central nervous system projection neuron axonogenesis (GO:0021952)2.98710391
78auditory behavior (GO:0031223)2.97668379
79negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.96487098
80membrane hyperpolarization (GO:0060081)2.95378633
81dendritic spine organization (GO:0097061)2.94817944
82glycine transport (GO:0015816)2.90538276
83regulation of synaptic transmission, glutamatergic (GO:0051966)2.89610267
84cellular sodium ion homeostasis (GO:0006883)2.89491544
85regulation of dendritic spine development (GO:0060998)2.88685185
86regulation of neurotransmitter secretion (GO:0046928)2.88245491
87activation of protein kinase A activity (GO:0034199)2.87843233
88cerebral cortex radially oriented cell migration (GO:0021799)2.87472653
89negative regulation of dendrite morphogenesis (GO:0050774)2.87430404
90G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.87090539
91neuromuscular process controlling balance (GO:0050885)2.86631995
92synapse assembly (GO:0007416)2.86067977
93synaptic vesicle endocytosis (GO:0048488)2.85747879
94regulation of vesicle fusion (GO:0031338)2.83288160
95fatty acid elongation (GO:0030497)2.82218388
96positive regulation of synapse assembly (GO:0051965)2.80058758
97cellular response to monoamine stimulus (GO:0071868)2.79791951
98cellular response to catecholamine stimulus (GO:0071870)2.79791951
99positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.78543498
100learning (GO:0007612)2.76197231
101regulation of respiratory system process (GO:0044065)2.76194930
102negative regulation of protein localization to cell surface (GO:2000009)2.75801480
103negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.74089682
104positive regulation of dendritic spine development (GO:0060999)2.74062282
105amino acid import (GO:0043090)2.73997592
106cerebellar Purkinje cell differentiation (GO:0021702)2.73891602
107regulation of neurotransmitter transport (GO:0051588)2.73663860
108synapse organization (GO:0050808)2.73642578
109response to auditory stimulus (GO:0010996)2.72967449
110negative regulation of axonogenesis (GO:0050771)2.72803618
111cell migration in hindbrain (GO:0021535)2.72520374
112positive regulation of synaptic transmission, GABAergic (GO:0032230)2.72132144
113nerve growth factor signaling pathway (GO:0038180)2.71936509
114regulation of synapse maturation (GO:0090128)2.71907370
115regulation of neurotransmitter levels (GO:0001505)2.71662541
116prepulse inhibition (GO:0060134)2.69690094
117negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.68084253
118membrane assembly (GO:0071709)2.66036153
119astrocyte development (GO:0014002)2.63869127
120cell differentiation in hindbrain (GO:0021533)2.55940234
121establishment of nucleus localization (GO:0040023)2.53136996
122cell communication involved in cardiac conduction (GO:0086065)2.51904041
123cerebellar Purkinje cell layer development (GO:0021680)2.51760070
124regulation of NFAT protein import into nucleus (GO:0051532)2.50987703
125regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.48297184
126neuromuscular process (GO:0050905)2.48119816
127axon extension (GO:0048675)2.47846569
128regulation of dendrite morphogenesis (GO:0048814)2.46591763
129suckling behavior (GO:0001967)2.45675664
130myelination in peripheral nervous system (GO:0022011)2.43905001
131peripheral nervous system axon ensheathment (GO:0032292)2.43905001
132positive regulation of dendrite development (GO:1900006)2.42466433
133adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.41933664
134positive regulation of dendritic spine morphogenesis (GO:0061003)2.41717063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.11195146
2GBX2_23144817_ChIP-Seq_PC3_Human3.57832666
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99762971
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98988804
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96854029
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66466986
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66466986
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.54976556
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.48226429
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.47888394
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47602945
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.44239095
13THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.42073584
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.40506669
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.36448701
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.27612993
17* DROSHA_22980978_ChIP-Seq_HELA_Human2.24120962
18REST_21632747_ChIP-Seq_MESCs_Mouse2.22323823
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.20501620
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16461790
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.16093042
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.13916037
23KDM2B_26808549_Chip-Seq_K562_Human2.03254511
24ZFP281_18757296_ChIP-ChIP_E14_Mouse1.97564091
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.94746706
26AR_21572438_ChIP-Seq_LNCaP_Human1.93631951
27TAF15_26573619_Chip-Seq_HEK293_Human1.90633103
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.88588975
29KDM2B_26808549_Chip-Seq_SUP-B15_Human1.84595958
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83975725
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83317298
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.79280824
33ZFP281_27345836_Chip-Seq_ESCs_Mouse1.79225592
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.75095099
35SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.70648603
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69779362
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.69086939
38SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.68998807
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.67263104
40TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.66401731
41ESR2_21235772_ChIP-Seq_MCF-7_Human1.65451614
42CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.63299511
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60033099
44PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56767422
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.55461648
46SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53716637
47RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.53540550
48SMAD4_21799915_ChIP-Seq_A2780_Human1.53269135
49DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.52894380
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.51149793
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.50685809
52EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50468602
53TRIM28_21343339_ChIP-Seq_HEK293_Human1.48632718
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46376301
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.45457706
56KDM2B_26808549_Chip-Seq_DND41_Human1.43281782
57P300_19829295_ChIP-Seq_ESCs_Human1.42311216
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.40852584
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39789793
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.38413267
61CTNNB1_20460455_ChIP-Seq_HCT116_Human1.38099182
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.34572570
63CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32943641
64EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31073494
65BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30740999
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30325931
67* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29063439
68KDM2B_26808549_Chip-Seq_JURKAT_Human1.29032134
69LXR_22292898_ChIP-Seq_THP-1_Human1.27200135
70RING1B_27294783_Chip-Seq_ESCs_Mouse1.26026122
71TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25802456
72* STAT3_23295773_ChIP-Seq_U87_Human1.25561328
73GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24532414
74SOX2_21211035_ChIP-Seq_LN229_Gbm1.23745642
75POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20937579
76* RING1B_27294783_Chip-Seq_NPCs_Mouse1.18877020
77* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18198582
78WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17508995
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15424363
80ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.15127353
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14872644
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.14512154
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14181805
84* ER_23166858_ChIP-Seq_MCF-7_Human1.13569892
85RNF2_27304074_Chip-Seq_NSC_Mouse1.13247270
86TCF7_22412390_ChIP-Seq_EML_Mouse1.12796094
87* AR_25329375_ChIP-Seq_VCAP_Human1.12744708
88ZNF274_21170338_ChIP-Seq_K562_Hela1.10878457
89TCF4_23295773_ChIP-Seq_U87_Human1.10336733
90KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10123599
91FUS_26573619_Chip-Seq_HEK293_Human1.09958651
92TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09052525
93AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08695189
94P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08645466
95AR_19668381_ChIP-Seq_PC3_Human1.08179783
96AHR_22903824_ChIP-Seq_MCF-7_Human1.07883154
97VDR_22108803_ChIP-Seq_LS180_Human1.07471888
98TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07412319
99TP53_20018659_ChIP-ChIP_R1E_Mouse1.06349684
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04553116
101SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04439922
102RUNX2_22187159_ChIP-Seq_PCA_Human1.02764822
103TET1_21490601_ChIP-Seq_MESCs_Mouse1.02155418
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01406780
105P300_27058665_Chip-Seq_ZR-75-30cells_Human1.01057025
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00450562
107ISL1_27105846_Chip-Seq_CPCs_Mouse1.00170598
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99572876
109SMAD_19615063_ChIP-ChIP_OVARY_Human0.99352124
110YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98207439
111* PRDM14_20953172_ChIP-Seq_ESCs_Human0.97992284
112TP53_16413492_ChIP-PET_HCT116_Human0.97971929
113IGF1R_20145208_ChIP-Seq_DFB_Human0.96850939
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96515861
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96515861
116EP300_21415370_ChIP-Seq_HL-1_Mouse0.95612590
117RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95574208
118CLOCK_20551151_ChIP-Seq_293T_Human0.95274934
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94987903
120NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94353942
121ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94198145
122GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94002226
123DNAJC2_21179169_ChIP-ChIP_NT2_Human0.93781102
124STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.92585661
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92006088
126RBPJ_22232070_ChIP-Seq_NCS_Mouse0.91243693
127PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90995377
128RARG_19884340_ChIP-ChIP_MEFs_Mouse0.90806428
129CTCF_27219007_Chip-Seq_Bcells_Human0.90518271
130* SMAD4_21741376_ChIP-Seq_HESCs_Human0.90152763
131KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.90087358
132NANOG_18555785_Chip-Seq_ESCs_Mouse0.89751792
133* TP53_23651856_ChIP-Seq_MEFs_Mouse0.89122292
134STAT6_21828071_ChIP-Seq_BEAS2B_Human0.88761798
135TP53_18474530_ChIP-ChIP_U2OS_Human0.87934903
136TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87584433
137UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.86666712
138CREB1_26743006_Chip-Seq_LNCaP_Human0.86337380
139SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85258131
140SMC4_20622854_ChIP-Seq_HELA_Human0.84475256
141RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.84310237
142* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.82834566
143TBX20_22080862_ChIP-Seq_HEART_Mouse0.79849222
144TBX20_22328084_ChIP-Seq_HEART_Mouse0.79849222
145SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.77354129

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.40311973
2MP0003880_abnormal_central_pattern4.86773173
3MP0004270_analgesia3.80064458
4MP0003635_abnormal_synaptic_transmissio3.70913603
5MP0009745_abnormal_behavioral_response3.04917128
6MP0002064_seizures3.03620018
7MP0002063_abnormal_learning/memory/cond2.97603940
8MP0005423_abnormal_somatic_nervous2.91254249
9MP0009046_muscle_twitch2.90141082
10MP0001486_abnormal_startle_reflex2.75957963
11MP0002272_abnormal_nervous_system2.71488362
12MP0002572_abnormal_emotion/affect_behav2.57855275
13MP0000778_abnormal_nervous_system2.47830770
14MP0001968_abnormal_touch/_nociception2.46703741
15MP0002734_abnormal_mechanical_nocicepti2.45911871
16MP0000920_abnormal_myelination2.27408255
17MP0003705_abnormal_hypodermis_morpholog2.21774950
18MP0003329_amyloid_beta_deposits2.19978174
19MP0002822_catalepsy2.05310375
20MP0001440_abnormal_grooming_behavior2.02362165
21MP0004885_abnormal_endolymph2.01813799
22MP0001529_abnormal_vocalization1.97297343
23MP0002733_abnormal_thermal_nociception1.96329672
24MP0002735_abnormal_chemical_nociception1.93763965
25MP0002067_abnormal_sensory_capabilities1.91394981
26MP0002736_abnormal_nociception_after1.89539101
27MP0001970_abnormal_pain_threshold1.86724021
28MP0004924_abnormal_behavior1.82361826
29MP0005386_behavior/neurological_phenoty1.82361826
30MP0008569_lethality_at_weaning1.79751019
31MP0001501_abnormal_sleep_pattern1.78397264
32MP0002184_abnormal_innervation1.70841011
33MP0001905_abnormal_dopamine_level1.69857444
34MP0000955_abnormal_spinal_cord1.68033506
35MP0002557_abnormal_social/conspecific_i1.67031403
36MP0004742_abnormal_vestibular_system1.64274693
37MP0002882_abnormal_neuron_morphology1.57076722
38MP0003690_abnormal_glial_cell1.57050462
39MP0006276_abnormal_autonomic_nervous1.52133455
40MP0004142_abnormal_muscle_tone1.50796436
41MP0004811_abnormal_neuron_physiology1.50112263
42MP0002066_abnormal_motor_capabilities/c1.49038250
43MP0009780_abnormal_chondrocyte_physiolo1.41204065
44MP0003634_abnormal_glial_cell1.40012238
45MP0001958_emphysema1.35802291
46MP0003633_abnormal_nervous_system1.34212722
47MP0005551_abnormal_eye_electrophysiolog1.32459619
48MP0001984_abnormal_olfaction1.31597275
49MP0005409_darkened_coat_color1.30047982
50MP0002229_neurodegeneration1.29922236
51MP0001485_abnormal_pinna_reflex1.28587961
52MP0003631_nervous_system_phenotype1.28511009
53MP0003787_abnormal_imprinting1.28233538
54MP0005646_abnormal_pituitary_gland1.26482156
55MP0003632_abnormal_nervous_system1.25224776
56MP0002152_abnormal_brain_morphology1.23083289
57MP0004858_abnormal_nervous_system1.20459544
58MP0001502_abnormal_circadian_rhythm1.19166435
59MP0004145_abnormal_muscle_electrophysio1.15565120
60MP0003123_paternal_imprinting1.11959715
61MP0004130_abnormal_muscle_cell1.11272591
62MP0003283_abnormal_digestive_organ1.10689784
63MP0005171_absent_coat_pigmentation1.10509152
64MP0003091_abnormal_cell_migration1.08946171
65MP0005645_abnormal_hypothalamus_physiol1.06787642
66MP0001963_abnormal_hearing_physiology1.06049297
67MP0001348_abnormal_lacrimal_gland1.05843171
68MP0001177_atelectasis1.04327198
69MP0002752_abnormal_somatic_nervous1.02528816
70MP0005623_abnormal_meninges_morphology1.02364044
71MP0003879_abnormal_hair_cell0.99020479
72MP0003122_maternal_imprinting0.96272865
73MP0002249_abnormal_larynx_morphology0.95918170
74MP0002909_abnormal_adrenal_gland0.94593235
75MP0000604_amyloidosis0.94407233
76MP0000534_abnormal_ureter_morphology0.94259644
77MP0008438_abnormal_cutaneous_collagen0.93121101
78MP0005076_abnormal_cell_differentiation0.92224627
79MP0000751_myopathy0.91218079
80MP0001299_abnormal_eye_distance/0.90746231
81MP0000579_abnormal_nail_morphology0.87079062
82MP0001188_hyperpigmentation0.86729206
83MP0004085_abnormal_heartbeat0.85805167
84MP0005394_taste/olfaction_phenotype0.82654791
85MP0005499_abnormal_olfactory_system0.82654791
86MP0002069_abnormal_eating/drinking_beha0.82573665
87MP0000631_abnormal_neuroendocrine_gland0.81443455
88MP0005248_abnormal_Harderian_gland0.81371249
89MP0000013_abnormal_adipose_tissue0.77828891
90MP0003861_abnormal_nervous_system0.77770617
91MP0003137_abnormal_impulse_conducting0.77665070
92MP0008874_decreased_physiological_sensi0.77208466
93MP0006072_abnormal_retinal_apoptosis0.76025055
94MP0001346_abnormal_lacrimal_gland0.75912716
95MP0000462_abnormal_digestive_system0.75859276
96MP0002896_abnormal_bone_mineralization0.75673541
97MP0001849_ear_inflammation0.74227309
98MP0000026_abnormal_inner_ear0.72375694
99MP0003172_abnormal_lysosome_physiology0.71646533
100MP0002089_abnormal_postnatal_growth/wei0.68886214
101MP0002090_abnormal_vision0.68702632
102MP0003075_altered_response_to0.68571052
103MP0000537_abnormal_urethra_morphology0.68357736
104MP0005388_respiratory_system_phenotype0.66642646
105MP0002133_abnormal_respiratory_system0.66642646
106MP0003938_abnormal_ear_development0.66500387
107MP0002081_perinatal_lethality0.65398128
108MP0003183_abnormal_peptide_metabolism0.64988230
109MP0003045_fibrosis0.64845554
110MP0005195_abnormal_posterior_eye0.64039378
111MP0003115_abnormal_respiratory_system0.63478604
112MP0004134_abnormal_chest_morphology0.63095341
113MP0001943_abnormal_respiration0.62825697
114MP0000569_abnormal_digit_pigmentation0.62275627
115MP0005253_abnormal_eye_physiology0.62237239
116MP0004043_abnormal_pH_regulation0.59865120
117MP0003279_aneurysm0.59581519
118MP0000733_abnormal_muscle_development0.59327605
119MP0004215_abnormal_myocardial_fiber0.59100747
120MP0003136_yellow_coat_color0.59021555
121MP0008872_abnormal_physiological_respon0.57203315
122MP0010769_abnormal_survival0.56996449
123MP0010770_preweaning_lethality0.56810687
124MP0002082_postnatal_lethality0.56810687
125MP0000747_muscle_weakness0.56343472
126MP0010768_mortality/aging0.52897598
127MP0002837_dystrophic_cardiac_calcinosis0.52584336
128MP0005535_abnormal_body_temperature0.52430239
129MP0003950_abnormal_plasma_membrane0.50559561

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.88975608
2Myokymia (HP:0002411)5.49703384
3Neurofibrillary tangles (HP:0002185)4.56491401
4Epileptic encephalopathy (HP:0200134)4.50965826
5Focal seizures (HP:0007359)4.50658648
6Supranuclear gaze palsy (HP:0000605)4.07968343
7Obstructive sleep apnea (HP:0002870)4.04551728
8Abnormality of the corticospinal tract (HP:0002492)4.03963257
9Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.98261942
10Degeneration of the lateral corticospinal tracts (HP:0002314)3.98261942
11Cerebral inclusion bodies (HP:0100314)3.87230202
12Progressive cerebellar ataxia (HP:0002073)3.66488074
13Atonic seizures (HP:0010819)3.63689851
14Ankle clonus (HP:0011448)3.57671856
15Action tremor (HP:0002345)3.56510773
16Visual hallucinations (HP:0002367)3.55152702
17Broad-based gait (HP:0002136)3.51499750
18Dysmetria (HP:0001310)3.40937756
19Insidious onset (HP:0003587)3.30417690
20Termporal pattern (HP:0011008)3.30417690
21Spastic gait (HP:0002064)3.23039871
22Intention tremor (HP:0002080)3.11291173
23Hyperventilation (HP:0002883)3.08117526
24Scanning speech (HP:0002168)3.07171948
25Poor eye contact (HP:0000817)3.01682182
26Febrile seizures (HP:0002373)2.96700613
27Absence seizures (HP:0002121)2.92782516
28Dysdiadochokinesis (HP:0002075)2.87962285
29Gaze-evoked nystagmus (HP:0000640)2.87737769
30Generalized tonic-clonic seizures (HP:0002069)2.86105153
31Dialeptic seizures (HP:0011146)2.85356465
32Peripheral hypomyelination (HP:0007182)2.84987626
33Hyperacusis (HP:0010780)2.82130055
34Drooling (HP:0002307)2.79230855
35Excessive salivation (HP:0003781)2.79230855
36Insomnia (HP:0100785)2.75954506
37Truncal ataxia (HP:0002078)2.70147167
38Megalencephaly (HP:0001355)2.69923294
39Urinary urgency (HP:0000012)2.68170956
40Limb dystonia (HP:0002451)2.67409223
41Abnormal social behavior (HP:0012433)2.65357010
42Impaired social interactions (HP:0000735)2.65357010
43Mutism (HP:0002300)2.65257539
44Urinary bladder sphincter dysfunction (HP:0002839)2.64102116
45Abnormal eating behavior (HP:0100738)2.61616360
46Shallow orbits (HP:0000586)2.53986726
47Progressive inability to walk (HP:0002505)2.53269131
48Impaired vibration sensation in the lower limbs (HP:0002166)2.51352450
49Turricephaly (HP:0000262)2.49732781
50Lower limb muscle weakness (HP:0007340)2.44459713
51Anxiety (HP:0000739)2.44349375
52Hemiparesis (HP:0001269)2.40444321
53Thickened helices (HP:0000391)2.39976493
54Pheochromocytoma (HP:0002666)2.39510414
55Depression (HP:0000716)2.38355128
56Akinesia (HP:0002304)2.37751026
57Arterial tortuosity (HP:0005116)2.36408779
58Amblyopia (HP:0000646)2.35887902
59Epileptiform EEG discharges (HP:0011182)2.35548866
60Onion bulb formation (HP:0003383)2.33276142
61EEG with generalized epileptiform discharges (HP:0011198)2.31329513
62Sensory axonal neuropathy (HP:0003390)2.30078943
63Absent speech (HP:0001344)2.26210758
64Hypsarrhythmia (HP:0002521)2.25396341
65Cerebral aneurysm (HP:0004944)2.25283141
66Annular pancreas (HP:0001734)2.23454255
67Vascular tortuosity (HP:0004948)2.23351966
68Generalized myoclonic seizures (HP:0002123)2.23092715
69Protrusio acetabuli (HP:0003179)2.23058570
70Retinal dysplasia (HP:0007973)2.22420889
71Postural instability (HP:0002172)2.21596747
72Abnormality of binocular vision (HP:0011514)2.21366235
73Diplopia (HP:0000651)2.21366235
74Genetic anticipation (HP:0003743)2.17570925
75Bronchomalacia (HP:0002780)2.14683919
76Fetal akinesia sequence (HP:0001989)2.11973016
77Torticollis (HP:0000473)2.11137417
78Blue irides (HP:0000635)2.09740052
79Polyphagia (HP:0002591)2.09407926
80Aplasia involving bones of the upper limbs (HP:0009823)2.08134385
81Aplasia of the phalanges of the hand (HP:0009802)2.08134385
82Aplasia involving bones of the extremities (HP:0009825)2.08134385
83Vertebral arch anomaly (HP:0008438)2.05839901
84Pointed chin (HP:0000307)2.05084519
85Mild short stature (HP:0003502)2.03963268
86Apathy (HP:0000741)2.02451272
87Clonus (HP:0002169)2.00416499
88Morphological abnormality of the pyramidal tract (HP:0002062)2.00268205
89Focal dystonia (HP:0004373)1.98199271
90Stereotypic behavior (HP:0000733)1.97568162
91Neuroendocrine neoplasm (HP:0100634)1.95695535
92Neuronal loss in central nervous system (HP:0002529)1.93413045
93Clumsiness (HP:0002312)1.93166437
94Abnormality of the lower motor neuron (HP:0002366)1.92409239
95Sleep apnea (HP:0010535)1.92406645
96Overgrowth (HP:0001548)1.92089136
97Mitral regurgitation (HP:0001653)1.91067733
98Abnormality of salivation (HP:0100755)1.90791095
99Overriding aorta (HP:0002623)1.89700096
100Lower limb amyotrophy (HP:0007210)1.89294336
101Dysmetric saccades (HP:0000641)1.88799089
102Macroorchidism (HP:0000053)1.88652316
103Lower limb asymmetry (HP:0100559)1.88515023
104Renovascular hypertension (HP:0100817)1.88298082
105Bowel incontinence (HP:0002607)1.87913401
106Difficulty running (HP:0009046)1.87826974
107Neonatal short-limb short stature (HP:0008921)1.86916140
108Rapidly progressive (HP:0003678)1.85897403
109Decreased motor nerve conduction velocity (HP:0003431)1.85433648
110Hyporeflexia of lower limbs (HP:0002600)1.85175629
111Elfin facies (HP:0004428)1.85106130
112Foot dorsiflexor weakness (HP:0009027)1.84949532
113Postural tremor (HP:0002174)1.84888413
114Specific learning disability (HP:0001328)1.83122667
115Spastic tetraparesis (HP:0001285)1.83080994
116Broad face (HP:0000283)1.82896907
117Bowel diverticulosis (HP:0005222)1.82217713
118Widely spaced teeth (HP:0000687)1.80851734
119Gait imbalance (HP:0002141)1.80223994
120Papilledema (HP:0001085)1.79100307
121Arnold-Chiari malformation (HP:0002308)1.78698166
122Agitation (HP:0000713)1.78647160
123Bladder diverticulum (HP:0000015)1.78368531
124Ulnar bowing (HP:0003031)1.77399621
125Increased circulating renin level (HP:0000848)1.76716030
126Amyotrophic lateral sclerosis (HP:0007354)1.76438632
127Diminished motivation (HP:0000745)1.75487710
128Alacrima (HP:0000522)1.73420489
129Gait ataxia (HP:0002066)1.73354279
130Inability to walk (HP:0002540)1.73185284
131Abnormal large intestine physiology (HP:0012700)1.72191960
132Craniofacial dystonia (HP:0012179)1.71880536
133Abnormality of saccadic eye movements (HP:0000570)1.71542309
134Abnormality of the foot musculature (HP:0001436)1.70907715
135Tetraplegia (HP:0002445)1.69360720
136Hammertoe (HP:0001765)1.68821141
137Psychosis (HP:0000709)1.68470460
138Bradykinesia (HP:0002067)1.66947400
139Hemiplegia (HP:0002301)1.66559745
140Increased variability in muscle fiber diameter (HP:0003557)1.64074279
141Hyperparathyroidism (HP:0000843)1.63330410
142Aqueductal stenosis (HP:0002410)1.63182651
143Rigidity (HP:0002063)1.63165992
144Atrophic scars (HP:0001075)1.62845696
145Renal duplication (HP:0000075)1.61431848
146Genu recurvatum (HP:0002816)1.58894443
147Split foot (HP:0001839)1.57754944
148Broad metatarsal (HP:0001783)1.57751657
149Hypercortisolism (HP:0001578)1.57039675
150Precocious puberty (HP:0000826)1.56856312

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.89526988
2EPHA43.69071057
3NTRK33.20696058
4MAP3K92.68472638
5STK392.64280668
6MAP3K42.59040119
7TRIB32.58670919
8RIPK12.55653751
9NTRK22.33723708
10OXSR12.27664367
11PAK62.17694660
12PNCK2.15280179
13CASK2.13574487
14MAP2K72.13296357
15MINK12.10587345
16TNIK1.97710900
17NTRK11.79953061
18CDK191.76339122
19DAPK21.73673171
20UHMK11.66653908
21PDGFRA1.55175767
22PRPF4B1.54062799
23CDK51.50479312
24MAPK131.47582890
25MAP2K41.41745412
26PKN11.39877347
27KSR21.39851452
28PLK21.37231430
29TYRO31.34823653
30BCR1.33899819
31SGK31.32150729
32FGFR21.29584608
33EPHB11.27373518
34CDK121.26626394
35CAMK2B1.25891373
36SGK4941.23264291
37SGK2231.23264291
38WNK11.22065178
39KSR11.17841054
40PHKG11.17666805
41PHKG21.17666805
42CSNK1G21.15615827
43CAMKK11.13486462
44PAK31.13106099
45MAPKAPK51.13054971
46CAMK2A1.09197205
47PRKD31.09013413
48EEF2K1.08558637
49FES1.04407032
50WNK41.02278361
51SIK11.02152227
52CDK141.01953097
53RIPK40.97975298
54GRK50.97691917
55CDK180.96152861
56CDK150.96128522
57ROCK20.95822284
58MAP3K20.93358361
59NEK60.92963329
60PRKCG0.91719835
61CSNK1G30.89609288
62MARK20.89484858
63CAMK2D0.89140752
64PKN20.88398808
65FGFR40.86871758
66MAPK120.86687406
67CAMKK20.84408044
68CDK11A0.83802499
69STK110.83063401
70LATS20.82473073
71CSNK1A1L0.82160912
72FGR0.79584480
73LIMK10.79514088
74PDGFRB0.76507289
75DYRK1A0.76016705
76MAP3K120.75277703
77SIK20.74814484
78PINK10.73199957
79CAMK1G0.72776588
80DYRK20.72265232
81PRKCH0.71637759
82RET0.71515477
83PRKCE0.69430194
84CAMK10.67824118
85CAMK2G0.67667543
86MTOR0.66505739
87MAP3K100.65726208
88FGFR30.64802833
89ICK0.63954260
90ARAF0.63516804
91MOS0.62411424
92CAMK40.62367204
93RPS6KA20.61986123
94SGK10.61001448
95DMPK0.60587855
96CSNK1G10.59997630
97MAP3K60.59582318
98PDPK10.59520302
99PTK2B0.57579210
100BMPR20.56629972
101SMG10.56471692
102CAMK1D0.54709002
103PTK20.54677680
104STK380.54324115
105FYN0.54060208
106TTN0.52946420
107WNK30.52867056
108MAP3K10.51982461
109DAPK10.51361983
110MAP3K130.50875719
111EPHB20.49614108
112ERBB20.47301263
113BRD40.46892945
114PRKG10.46797966
115PRKCZ0.46698173
116PDK10.45801477
117CDC42BPA0.45379024
118MAPK100.45162695
119MAP3K70.45092375
120IRAK20.44898368
121DDR20.44823029
122SGK20.43859344
123RPS6KA30.43305878
124JAK10.42439400
125PRKD10.41862188
126LMTK20.41410051
127RAF10.40203287
128PAK20.40060970
129ALK0.39666872
130FER0.38041749
131ROCK10.37556254

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.26514647
2GABAergic synapse_Homo sapiens_hsa047272.72263970
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.62442047
4Glutamatergic synapse_Homo sapiens_hsa047242.61550929
5Synaptic vesicle cycle_Homo sapiens_hsa047212.61375923
6Circadian entrainment_Homo sapiens_hsa047132.51450621
7Morphine addiction_Homo sapiens_hsa050322.40485582
8Long-term potentiation_Homo sapiens_hsa047202.20699788
9Olfactory transduction_Homo sapiens_hsa047402.12753399
10Dopaminergic synapse_Homo sapiens_hsa047282.09227488
11Amphetamine addiction_Homo sapiens_hsa050312.04883653
12Long-term depression_Homo sapiens_hsa047301.97527496
13Serotonergic synapse_Homo sapiens_hsa047261.92563763
14Salivary secretion_Homo sapiens_hsa049701.92219891
15Cholinergic synapse_Homo sapiens_hsa047251.86371909
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.74175067
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.73806235
18Gastric acid secretion_Homo sapiens_hsa049711.73088100
19Axon guidance_Homo sapiens_hsa043601.68777930
20Cocaine addiction_Homo sapiens_hsa050301.65303604
21Taste transduction_Homo sapiens_hsa047421.61740748
22Renin secretion_Homo sapiens_hsa049241.60324401
23Insulin secretion_Homo sapiens_hsa049111.57722963
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52860083
25Oxytocin signaling pathway_Homo sapiens_hsa049211.49184622
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.48153428
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45143280
28Gap junction_Homo sapiens_hsa045401.39246219
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.32166602
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31011987
31Calcium signaling pathway_Homo sapiens_hsa040201.30319320
32Collecting duct acid secretion_Homo sapiens_hsa049661.28157169
33Thyroid hormone signaling pathway_Homo sapiens_hsa049191.27236100
34GnRH signaling pathway_Homo sapiens_hsa049121.26097472
35Phototransduction_Homo sapiens_hsa047441.18971341
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17044893
37cAMP signaling pathway_Homo sapiens_hsa040241.14478626
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.12189408
39Estrogen signaling pathway_Homo sapiens_hsa049151.09107558
40Steroid biosynthesis_Homo sapiens_hsa001001.08031809
41ErbB signaling pathway_Homo sapiens_hsa040121.07802648
42Non-small cell lung cancer_Homo sapiens_hsa052231.07724803
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06581269
44Melanogenesis_Homo sapiens_hsa049161.04856957
45Chronic myeloid leukemia_Homo sapiens_hsa052201.04818938
46Nitrogen metabolism_Homo sapiens_hsa009101.02222122
47Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.00753183
48Cardiac muscle contraction_Homo sapiens_hsa042601.00683797
49Vascular smooth muscle contraction_Homo sapiens_hsa042700.97832143
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.97285290
51Ether lipid metabolism_Homo sapiens_hsa005650.96480567
52Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.96055124
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93448242
54mTOR signaling pathway_Homo sapiens_hsa041500.93036990
55Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92450441
56Glioma_Homo sapiens_hsa052140.91995803
57Dorso-ventral axis formation_Homo sapiens_hsa043200.91743121
58Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.90729896
59Notch signaling pathway_Homo sapiens_hsa043300.90598685
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89996536
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.89576720
62Renal cell carcinoma_Homo sapiens_hsa052110.89452000
63Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89321880
64Vibrio cholerae infection_Homo sapiens_hsa051100.88981904
65Type II diabetes mellitus_Homo sapiens_hsa049300.87804374
66Bile secretion_Homo sapiens_hsa049760.86611814
67Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.86274573
68Choline metabolism in cancer_Homo sapiens_hsa052310.84173519
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.83635379
70Focal adhesion_Homo sapiens_hsa045100.82463641
71Fatty acid elongation_Homo sapiens_hsa000620.82068239
72Pancreatic secretion_Homo sapiens_hsa049720.81242877
73Insulin signaling pathway_Homo sapiens_hsa049100.80802376
74Colorectal cancer_Homo sapiens_hsa052100.80483788
75Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80002653
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.79493367
77Prolactin signaling pathway_Homo sapiens_hsa049170.79380618
78Longevity regulating pathway - mammal_Homo sapiens_hsa042110.78989686
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77784803
80Pancreatic cancer_Homo sapiens_hsa052120.77726677
81Adherens junction_Homo sapiens_hsa045200.75821021
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.75665147
83Dilated cardiomyopathy_Homo sapiens_hsa054140.74474671
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.73751082
85Ras signaling pathway_Homo sapiens_hsa040140.73641378
86AMPK signaling pathway_Homo sapiens_hsa041520.71079662
87Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70768531
88Butanoate metabolism_Homo sapiens_hsa006500.70613482
89MAPK signaling pathway_Homo sapiens_hsa040100.69736319
90Amoebiasis_Homo sapiens_hsa051460.67994739
91Alzheimers disease_Homo sapiens_hsa050100.67574733
92Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66473381
93Proteoglycans in cancer_Homo sapiens_hsa052050.64962045
94B cell receptor signaling pathway_Homo sapiens_hsa046620.64044177
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63327241
96Glucagon signaling pathway_Homo sapiens_hsa049220.62553825
97Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61331099
98Thyroid hormone synthesis_Homo sapiens_hsa049180.59718947
99Hippo signaling pathway_Homo sapiens_hsa043900.59638449
100Rap1 signaling pathway_Homo sapiens_hsa040150.58531087
101Acute myeloid leukemia_Homo sapiens_hsa052210.57441555
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.57030983
103Wnt signaling pathway_Homo sapiens_hsa043100.56972168
104Endocytosis_Homo sapiens_hsa041440.56695006
105MicroRNAs in cancer_Homo sapiens_hsa052060.56148835
106Tight junction_Homo sapiens_hsa045300.54696661
107Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54515036
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53841282
109Ovarian steroidogenesis_Homo sapiens_hsa049130.53461926
110ECM-receptor interaction_Homo sapiens_hsa045120.53305669
111Oxidative phosphorylation_Homo sapiens_hsa001900.52973019
112Oocyte meiosis_Homo sapiens_hsa041140.52585813
113FoxO signaling pathway_Homo sapiens_hsa040680.51934644
114HIF-1 signaling pathway_Homo sapiens_hsa040660.50354341
115SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49571818
116Platelet activation_Homo sapiens_hsa046110.48469237
117VEGF signaling pathway_Homo sapiens_hsa043700.47953848
118Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46218474
119Alcoholism_Homo sapiens_hsa050340.45351604
120Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43722808
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43517593
122Hedgehog signaling pathway_Homo sapiens_hsa043400.43248455
123Prion diseases_Homo sapiens_hsa050200.43204608
124Inositol phosphate metabolism_Homo sapiens_hsa005620.41043251
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.39935876
126Parkinsons disease_Homo sapiens_hsa050120.38574955
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38137090
128Carbohydrate digestion and absorption_Homo sapiens_hsa049730.34986415
129Sphingolipid metabolism_Homo sapiens_hsa006000.33887613
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33643461
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.32506303
132Glycerophospholipid metabolism_Homo sapiens_hsa005640.32432503
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32033945
134Endometrial cancer_Homo sapiens_hsa052130.30853500
135African trypanosomiasis_Homo sapiens_hsa051430.30486041

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