FAM187B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)9.78166466
2fusion of sperm to egg plasma membrane (GO:0007342)9.19121961
3acrosome reaction (GO:0007340)9.13523414
4cell wall macromolecule catabolic process (GO:0016998)9.07695289
5cell wall macromolecule metabolic process (GO:0044036)9.07695289
6axonemal dynein complex assembly (GO:0070286)9.03093049
7multicellular organism reproduction (GO:0032504)8.34466099
8epithelial cilium movement (GO:0003351)8.33276177
9sperm-egg recognition (GO:0035036)8.18403593
10motile cilium assembly (GO:0044458)8.11507848
11sexual reproduction (GO:0019953)7.70438338
12binding of sperm to zona pellucida (GO:0007339)7.47000974
13acrosome assembly (GO:0001675)7.21488750
14cell-cell recognition (GO:0009988)7.21455540
15spermatid development (GO:0007286)7.20594529
16cilium or flagellum-dependent cell motility (GO:0001539)7.09889552
17cilium movement (GO:0003341)7.06826306
18regulation of cilium movement (GO:0003352)6.99599271
19reproduction (GO:0000003)6.99104147
20plasma membrane fusion (GO:0045026)6.90107405
21rRNA methylation (GO:0031167)6.89220640
22phosphatidylethanolamine biosynthetic process (GO:0006646)6.52991373
23cellular ketone body metabolic process (GO:0046950)6.16657505
24phosphatidylethanolamine metabolic process (GO:0046337)6.03518112
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.99587795
26protein targeting to Golgi (GO:0000042)5.90451254
27rRNA modification (GO:0000154)5.79512164
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.76373318
29single fertilization (GO:0007338)5.73293554
30establishment of protein localization to Golgi (GO:0072600)5.67235425
31microtubule depolymerization (GO:0007019)5.51335380
32retrograde transport, vesicle recycling within Golgi (GO:0000301)5.49510497
33ketone body metabolic process (GO:1902224)5.44429274
34male meiosis (GO:0007140)5.38787021
35piRNA metabolic process (GO:0034587)5.37816913
36sperm capacitation (GO:0048240)5.32840143
37regulation of Rab GTPase activity (GO:0032313)5.25176173
38positive regulation of Rab GTPase activity (GO:0032851)5.25176173
39chromatin silencing (GO:0006342)5.21066748
40spermatogenesis (GO:0007283)4.94269020
41male gamete generation (GO:0048232)4.92198065
42single strand break repair (GO:0000012)4.87020648
43organic cation transport (GO:0015695)4.84365709
44fertilization (GO:0009566)4.72294078
45gamete generation (GO:0007276)4.61300533
46regulation of transcription involved in cell fate commitment (GO:0060850)4.60521227
47nucleus organization (GO:0006997)4.27952322
48DNA methylation involved in gamete generation (GO:0043046)4.23172569
49sequestering of actin monomers (GO:0042989)4.22563522
50calcium ion-dependent exocytosis (GO:0017156)4.21974896
51protein localization to Golgi apparatus (GO:0034067)4.20876455
52synaptonemal complex organization (GO:0070193)4.18771034
53negative regulation of inclusion body assembly (GO:0090084)4.16560596
54coenzyme catabolic process (GO:0009109)4.12879338
55centriole assembly (GO:0098534)4.06661853
56spermatid nucleus differentiation (GO:0007289)4.04307788
57germ cell development (GO:0007281)3.98405982
58GTP biosynthetic process (GO:0006183)3.93742363
59regulation of microtubule-based movement (GO:0060632)3.91521810
60regulation of centriole replication (GO:0046599)3.89757030
61intraciliary transport (GO:0042073)3.86851851
62synaptonemal complex assembly (GO:0007130)3.84875707
63negative regulation of Rho protein signal transduction (GO:0035024)3.78066709
64nucleosome disassembly (GO:0006337)3.76799732
65protein-DNA complex disassembly (GO:0032986)3.76799732
66male meiosis I (GO:0007141)3.70336707
67cellular process involved in reproduction in multicellular organism (GO:0022412)3.69103382
68cilium assembly (GO:0042384)3.62175754
69polyamine biosynthetic process (GO:0006596)3.61363225
70cilium organization (GO:0044782)3.59799741
71ventricular system development (GO:0021591)3.59616596
72response to acidic pH (GO:0010447)3.59481840
73negative regulation of gene expression, epigenetic (GO:0045814)3.59242007
74peptidyl-threonine dephosphorylation (GO:0035970)3.59142241
75multicellular organismal reproductive process (GO:0048609)3.57926860
76axoneme assembly (GO:0035082)3.53851663
77protein localization to cilium (GO:0061512)3.51521916
78glycerol ether metabolic process (GO:0006662)3.50324811
79regulation of inclusion body assembly (GO:0090083)3.48679311
80cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.46121518
81cell recognition (GO:0008037)3.43978787
82multicellular organismal movement (GO:0050879)3.40197439
83musculoskeletal movement (GO:0050881)3.40197439
84cerebral cortex neuron differentiation (GO:0021895)3.38176696
85cilium morphogenesis (GO:0060271)3.35083203
86regulation of interleukin-13 production (GO:0032656)3.35032419
87regulation of T-helper 2 cell differentiation (GO:0045628)3.34514595
88microtubule severing (GO:0051013)3.34066501
89centriole replication (GO:0007099)3.29351843
90cellular response to pH (GO:0071467)3.28091271
91RNA destabilization (GO:0050779)3.27357783
92ether metabolic process (GO:0018904)3.26313583
93homeostasis of number of cells within a tissue (GO:0048873)3.20581503
94histone H3-K9 demethylation (GO:0033169)3.18453557
95mesenchymal cell differentiation involved in renal system development (GO:2001012)3.17246381
96mesenchymal cell differentiation involved in kidney development (GO:0072161)3.17246381
97chromosome organization involved in meiosis (GO:0070192)3.14792986
98protein polyglutamylation (GO:0018095)3.14666582
99cranial nerve morphogenesis (GO:0021602)3.14593535
100UTP biosynthetic process (GO:0006228)3.12653208
101left/right pattern formation (GO:0060972)3.12260079
102DNA conformation change (GO:0071103)3.08612489
103nucleoside diphosphate phosphorylation (GO:0006165)3.07971142
104negative regulation of execution phase of apoptosis (GO:1900118)3.05366393
105cell differentiation involved in metanephros development (GO:0072202)3.03615736
106protein depolymerization (GO:0051261)3.02741289
107membrane protein intracellular domain proteolysis (GO:0031293)3.01847149
108meiotic nuclear division (GO:0007126)3.01834745
109microtubule polymerization or depolymerization (GO:0031109)3.00476555
110keratinocyte development (GO:0003334)2.95423812
111meiosis I (GO:0007127)2.95157975
112NAD biosynthetic process (GO:0009435)2.94171863
113positive regulation of endothelial cell differentiation (GO:0045603)2.90679644
114synapsis (GO:0007129)2.90097186
115negative regulation of histone methylation (GO:0031061)2.89370135
116guanosine-containing compound biosynthetic process (GO:1901070)2.87577215
117cellular component assembly involved in morphogenesis (GO:0010927)2.87576345
118DNA deamination (GO:0045006)2.85716641
119protein K11-linked deubiquitination (GO:0035871)2.82734163
120multicellular organismal development (GO:0007275)2.82297963
121peptidyl-proline hydroxylation (GO:0019511)2.79048679
122regulation of phosphoprotein phosphatase activity (GO:0043666)2.78846156
123positive regulation of skeletal muscle tissue development (GO:0048643)2.76652432
124nucleoside diphosphate catabolic process (GO:0009134)2.76542215
125regulation of somitogenesis (GO:0014807)2.76250973
126negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.74817547
127CTP metabolic process (GO:0046036)2.74408178
128CTP biosynthetic process (GO:0006241)2.74408178
129histone exchange (GO:0043486)2.74290205
130regulation of spindle checkpoint (GO:0090231)2.73267871
131polyol transport (GO:0015791)2.72959705
132seminiferous tubule development (GO:0072520)2.70448293
133GPI anchor biosynthetic process (GO:0006506)2.64412752
134UTP metabolic process (GO:0046051)2.62339476
135female gonad development (GO:0008585)2.61871258
136negative regulation of transcription by competitive promoter binding (GO:0010944)2.61695681
137pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.60668758
138nucleotide transmembrane transport (GO:1901679)2.57139621
139DNA packaging (GO:0006323)2.52336230
140meiotic cell cycle (GO:0051321)2.51134860
141alditol metabolic process (GO:0019400)2.51048425
142regulation of meiosis I (GO:0060631)2.49835555
143lactate metabolic process (GO:0006089)2.47866261
144chromosome condensation (GO:0030261)2.43141659
145left/right axis specification (GO:0070986)2.39179501
146glycerol metabolic process (GO:0006071)2.37686291
147GPI anchor metabolic process (GO:0006505)2.32415834
148DNA ligation (GO:0006266)2.30841583
149pharyngeal system development (GO:0060037)2.30157120
150negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.28133348
151nucleoside diphosphate metabolic process (GO:0009132)2.27412255
152sperm motility (GO:0030317)10.3150239

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.96613226
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.46392678
3MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.67831406
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.23630911
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.87682260
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.75328841
7VDR_22108803_ChIP-Seq_LS180_Human2.74898484
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.56962734
9EZH2_22144423_ChIP-Seq_EOC_Human2.49249157
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.28355451
11ELF1_20517297_ChIP-Seq_JURKAT_Human2.24923568
12IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.13084211
13CBP_20019798_ChIP-Seq_JUKART_Human2.13084211
14VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.12381509
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08029991
16SUZ12_27294783_Chip-Seq_NPCs_Mouse2.06678272
17ERA_21632823_ChIP-Seq_H3396_Human2.04677108
18NFE2_27457419_Chip-Seq_LIVER_Mouse2.03766948
19RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.92830019
20PCGF2_27294783_Chip-Seq_NPCs_Mouse1.92280814
21EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.91742104
22RAC3_21632823_ChIP-Seq_H3396_Human1.89371623
23EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.89171226
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.88909141
25DROSHA_22980978_ChIP-Seq_HELA_Human1.87481338
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.86767426
27CTCF_27219007_Chip-Seq_Bcells_Human1.85092570
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.83887002
29TAL1_26923725_Chip-Seq_HPCs_Mouse1.82997211
30TAF15_26573619_Chip-Seq_HEK293_Human1.80820645
31BCL6_27268052_Chip-Seq_Bcells_Human1.79884503
32WDR5_24793694_ChIP-Seq_LNCAP_Human1.79349517
33KAP1_22055183_ChIP-Seq_ESCs_Mouse1.76754505
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.73450709
35E2F1_20622854_ChIP-Seq_HELA_Human1.72999864
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.70746496
37TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70287088
38TDRD3_21172665_ChIP-Seq_MCF-7_Human1.69070015
39NANOG_18555785_Chip-Seq_ESCs_Mouse1.68991626
40YY1_22570637_ChIP-Seq_MALME-3M_Human1.68525935
41STAT1_17558387_ChIP-Seq_HELA_Human1.67966997
42BCOR_27268052_Chip-Seq_Bcells_Human1.67390707
43SMC4_20622854_ChIP-Seq_HELA_Human1.67000141
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.66588503
45RNF2_27304074_Chip-Seq_NSC_Mouse1.65481820
46RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.64822149
47EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.64724005
48P68_20966046_ChIP-Seq_HELA_Human1.64381680
49PHF8_20622854_ChIP-Seq_HELA_Human1.61887728
50TAF2_19829295_ChIP-Seq_ESCs_Human1.61580776
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.61530247
52IRF1_19129219_ChIP-ChIP_H3396_Human1.61459224
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60100704
54CTCF_20526341_ChIP-Seq_ESCs_Human1.57660789
55SUZ12_18555785_Chip-Seq_ESCs_Mouse1.56654407
56P53_22387025_ChIP-Seq_ESCs_Mouse1.56582767
57STAT3_18555785_Chip-Seq_ESCs_Mouse1.55060526
58AUTS2_25519132_ChIP-Seq_293T-REX_Human1.54374170
59TP63_22573176_ChIP-Seq_HFKS_Human1.53543985
60CRX_20693478_ChIP-Seq_RETINA_Mouse1.53426017
61MYC_19829295_ChIP-Seq_ESCs_Human1.53282832
62OCT4_20526341_ChIP-Seq_ESCs_Human1.52009876
63LXR_22292898_ChIP-Seq_THP-1_Human1.51759490
64P300_18555785_Chip-Seq_ESCs_Mouse1.51307387
65OCT4_18555785_Chip-Seq_ESCs_Mouse1.49798095
66KLF4_18555785_Chip-Seq_ESCs_Mouse1.49620597
67EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.49512608
68NMYC_18555785_Chip-Seq_ESCs_Mouse1.48618471
69KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.46827364
70ARNT_22903824_ChIP-Seq_MCF-7_Human1.46441007
71ESRRB_18555785_Chip-Seq_ESCs_Mouse1.45253701
72P300_27268052_Chip-Seq_Bcells_Human1.45239264
73PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.45075315
74SMAD4_21741376_ChIP-Seq_EPCs_Human1.43874972
75CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43431370
76RUNX1_27457419_Chip-Seq_LIVER_Mouse1.43122396
77AR_25329375_ChIP-Seq_VCAP_Human1.42433842
78CMYC_18555785_Chip-Seq_ESCs_Mouse1.42399357
79NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41816669
80CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.39912059
81KDM2B_26808549_Chip-Seq_REH_Human1.39173124
82GBX2_23144817_ChIP-Seq_PC3_Human1.38468126
83SOX2_18555785_Chip-Seq_ESCs_Mouse1.37654227
84SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36955586
85SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.36791830
86ZFX_18555785_Chip-Seq_ESCs_Mouse1.36203079
87E2F1_18555785_Chip-Seq_ESCs_Mouse1.36165990
88HNFA_21074721_ChIP-Seq_CACO-2_Human1.33422422
89SUZ12_27294783_Chip-Seq_ESCs_Mouse1.32887940
90CBX2_22325352_ChIP-Seq_293T-Rex_Human1.31321888
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31039873
92P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.30995773
93TP53_18474530_ChIP-ChIP_U2OS_Human1.30776478
94GATA3_21878914_ChIP-Seq_MCF-7_Human1.30763094
95SMAD3_21741376_ChIP-Seq_ESCs_Human1.30260025
96PU1_27457419_Chip-Seq_LIVER_Mouse1.30149816
97SMAD1_18555785_Chip-Seq_ESCs_Mouse1.30036644
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.29868446
99* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29205956
100OCT4_21477851_ChIP-Seq_ESCs_Mouse1.28764595
101KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.27789162
102GATA1_26923725_Chip-Seq_HPCs_Mouse1.27339901
103POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27091937
104PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.26617902
105RUNX_20019798_ChIP-Seq_JUKART_Human1.24917054
106GATA3_21867929_ChIP-Seq_TH1_Mouse1.24426819
107CEBPB_22108803_ChIP-Seq_LS180_Human1.24400735
108ETV1_20927104_ChIP-Seq_GIST48_Human1.23768297
109SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22981677
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.22754606
111FUS_26573619_Chip-Seq_HEK293_Human1.21729935
112CTCF_18555785_Chip-Seq_ESCs_Mouse1.20921981
113MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20912976
114ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.20552085
115P53_21459846_ChIP-Seq_SAOS-2_Human1.20453243
116SOX2_22085726_ChIP-Seq_NPCs_Mouse1.18678319
117SMRT_27268052_Chip-Seq_Bcells_Human1.18577308
118GATA3_21867929_ChIP-Seq_CD8_Mouse1.17640378
119SA1_27219007_Chip-Seq_Bcells_Human1.17549468
120NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17289498
121SMAD3_21741376_ChIP-Seq_EPCs_Human1.17047409
122GF1_26923725_Chip-Seq_HPCs_Mouse1.16660838
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15005153
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15005153
125EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13667691
126NFYB_21822215_ChIP-Seq_K562_Human1.13128398
127SMAD4_21741376_ChIP-Seq_HESCs_Human1.12339860
128P300_19829295_ChIP-Seq_ESCs_Human1.11342620
129TBL1_22424771_ChIP-Seq_293T_Human1.10976016
130TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10899408
131EZH2_27294783_Chip-Seq_ESCs_Mouse1.10685159
132CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08363355
133ERG_20517297_ChIP-Seq_VCAP_Human1.08180721
134SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.07808713
135TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07615588
136TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07528513
137KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07226143
138CTBP1_25329375_ChIP-Seq_LNCAP_Human1.06501971
139GATA6_21074721_ChIP-Seq_CACO-2_Human1.05402426
140TP63_19390658_ChIP-ChIP_HaCaT_Human1.03893896
141THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03831586
142BP1_19119308_ChIP-ChIP_Hs578T_Human1.03215495
143ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03179249
144CSB_26484114_Chip-Seq_FIBROBLAST_Human1.03149905
145NANOG_19829295_ChIP-Seq_ESCs_Human1.02401646
146SOX2_19829295_ChIP-Seq_ESCs_Human1.02401646
147RUNX1_26923725_Chip-Seq_HPCs_Mouse1.01609863
148PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.01532414
149OCT1_27270436_Chip-Seq_PROSTATE_Human1.01420242
150SA1_27219007_Chip-Seq_ERYTHROID_Human1.01122758
151PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.00948520
152RUNX2_22187159_ChIP-Seq_PCA_Human1.00571562
153REST_21632747_ChIP-Seq_MESCs_Mouse1.00561392
154DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00314867
155HOXB7_26014856_ChIP-Seq_BT474_Human1.00077048
156CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99691884
157ELF1_17652178_ChIP-ChIP_JURKAT_Human0.98836194
158AR_21572438_ChIP-Seq_LNCaP_Human0.98131959
159JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97397144
160NFYA_21822215_ChIP-Seq_K562_Human0.97380560
161OCT4_19829295_ChIP-Seq_ESCs_Human0.97344785
162KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.97137925
163ER_23166858_ChIP-Seq_MCF-7_Human0.96263511
164FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94145159
165FOXA1_25329375_ChIP-Seq_VCAP_Human0.94145159
166BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.93814233
167GF1B_26923725_Chip-Seq_HPCs_Mouse0.93603248
168* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.93559194
169SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.93402065
170FLI1_21867929_ChIP-Seq_TH2_Mouse0.90843421
171NANOG_20526341_ChIP-Seq_ESCs_Human0.89570922
172PHF8_20622853_ChIP-Seq_HELA_Human0.89321347
173UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89219346
174LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88336006
175RBPJ_21746931_ChIP-Seq_IB4_Human0.87612257

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.76022673
2MP0001348_abnormal_lacrimal_gland3.81668636
3MP0003698_abnormal_male_reproductive3.78648761
4MP0001929_abnormal_gametogenesis3.58950425
5MP0006292_abnormal_olfactory_placode2.93638609
6MP0000566_synostosis2.84634079
7MP0008877_abnormal_DNA_methylation2.48759754
8MP0001986_abnormal_taste_sensitivity2.38158570
9MP0003011_delayed_dark_adaptation2.31463733
10MP0002210_abnormal_sex_determination2.27919416
11MP0004381_abnormal_hair_follicle2.27126606
12MP0010386_abnormal_urinary_bladder2.22526099
13MP0003136_yellow_coat_color2.22067598
14MP0005379_endocrine/exocrine_gland_phen2.08263424
15MP0005377_hearing/vestibular/ear_phenot2.00306773
16MP0003878_abnormal_ear_physiology2.00306773
17MP0002161_abnormal_fertility/fecundity1.95656188
18MP0005670_abnormal_white_adipose1.91201377
19MP0003646_muscle_fatigue1.90440260
20MP0001984_abnormal_olfaction1.84162059
21MP0001145_abnormal_male_reproductive1.83990797
22MP0008058_abnormal_DNA_repair1.78483967
23MP0000653_abnormal_sex_gland1.75577382
24MP0002249_abnormal_larynx_morphology1.70942425
25MP0002234_abnormal_pharynx_morphology1.70118644
26MP0005646_abnormal_pituitary_gland1.64288326
27MP0005423_abnormal_somatic_nervous1.62134849
28MP0009053_abnormal_anal_canal1.61804129
29MP0000678_abnormal_parathyroid_gland1.54169900
30MP0001188_hyperpigmentation1.52840902
31MP0003718_maternal_effect1.51546670
32MP0002160_abnormal_reproductive_system1.46063428
33MP0002282_abnormal_trachea_morphology1.45613822
34MP0004742_abnormal_vestibular_system1.45172037
35MP0005075_abnormal_melanosome_morpholog1.43993688
36MP0004510_myositis1.39295707
37MP0005084_abnormal_gallbladder_morpholo1.37517736
38MP0002638_abnormal_pupillary_reflex1.36968836
39MP0005451_abnormal_body_composition1.36955611
40MP0002693_abnormal_pancreas_physiology1.35650195
41MP0001486_abnormal_startle_reflex1.34678237
42MP0002735_abnormal_chemical_nociception1.33086445
43MP0002822_catalepsy1.31142914
44MP0002277_abnormal_respiratory_mucosa1.30176133
45MP0003941_abnormal_skin_development1.29748390
46MP0008995_early_reproductive_senescence1.29617033
47MP0000534_abnormal_ureter_morphology1.25774298
48MP0002938_white_spotting1.25159458
49MP0000613_abnormal_salivary_gland1.23957057
50MP0002653_abnormal_ependyma_morphology1.23243096
51MP0001905_abnormal_dopamine_level1.22865047
52MP0005645_abnormal_hypothalamus_physiol1.21251342
53MP0001764_abnormal_homeostasis1.21110549
54MP0003195_calcinosis1.21020365
55MP0002138_abnormal_hepatobiliary_system1.20967094
56MP0001968_abnormal_touch/_nociception1.19843532
57MP0008789_abnormal_olfactory_epithelium1.19819081
58MP0006072_abnormal_retinal_apoptosis1.18770334
59MP0005310_abnormal_salivary_gland1.18182789
60MP0005248_abnormal_Harderian_gland1.17008076
61MP0000015_abnormal_ear_pigmentation1.16563180
62MP0005389_reproductive_system_phenotype1.14797140
63MP0004859_abnormal_synaptic_plasticity1.14064815
64MP0002132_abnormal_respiratory_system1.13914449
65MP0003786_premature_aging1.13754374
66MP0002127_abnormal_cardiovascular_syste1.13431238
67MP0005171_absent_coat_pigmentation1.10216329
68MP0005408_hypopigmentation1.06947088
69MP0002876_abnormal_thyroid_physiology1.05875792
70MP0002102_abnormal_ear_morphology1.05331517
71MP0000372_irregular_coat_pigmentation1.04012916
72MP0000026_abnormal_inner_ear1.03337140
73MP0004019_abnormal_vitamin_homeostasis1.01457454
74MP0005253_abnormal_eye_physiology1.00662305
75MP0009697_abnormal_copulation1.00534324
76MP0000013_abnormal_adipose_tissue1.00403598
77MP0005395_other_phenotype0.98409689
78MP0004043_abnormal_pH_regulation0.98265135
79MP0002163_abnormal_gland_morphology0.97343426
80MP0003693_abnormal_embryo_hatching0.94005632
81MP0000681_abnormal_thyroid_gland0.93722568
82MP0004133_heterotaxia0.93545192
83MP0001765_abnormal_ion_homeostasis0.92795440
84MP0005409_darkened_coat_color0.92649393
85MP0003879_abnormal_hair_cell0.91296143
86MP0003183_abnormal_peptide_metabolism0.89313642
87MP0004885_abnormal_endolymph0.88980286
88MP0001944_abnormal_pancreas_morphology0.88562133
89MP0000631_abnormal_neuroendocrine_gland0.87695244
90MP0005551_abnormal_eye_electrophysiolog0.86927276
91MP0000049_abnormal_middle_ear0.85705187
92MP0005636_abnormal_mineral_homeostasis0.85508714
93MP0005394_taste/olfaction_phenotype0.85183311
94MP0005499_abnormal_olfactory_system0.85183311
95MP0001963_abnormal_hearing_physiology0.85132936
96MP0000462_abnormal_digestive_system0.85107513
97MP0000538_abnormal_urinary_bladder0.84163725
98MP0005220_abnormal_exocrine_pancreas0.82934831
99MP0002229_neurodegeneration0.82893437
100MP0005647_abnormal_sex_gland0.82524701
101MP0005174_abnormal_tail_pigmentation0.81578472
102MP0003315_abnormal_perineum_morphology0.81458749
103MP0001664_abnormal_digestion0.81391773
104MP0005666_abnormal_adipose_tissue0.81154558
105MP0009379_abnormal_foot_pigmentation0.80305884
106MP0002095_abnormal_skin_pigmentation0.79605603
107MP0003724_increased_susceptibility_to0.79002103
108MP0000955_abnormal_spinal_cord0.78597392
109MP0001346_abnormal_lacrimal_gland0.77910910
110MP0002733_abnormal_thermal_nociception0.77804197
111MP0008569_lethality_at_weaning0.76920675
112MP0001485_abnormal_pinna_reflex0.76323590
113MP0009115_abnormal_fat_cell0.75994134
114MP0001879_abnormal_lymphatic_vessel0.75792805
115MP0000516_abnormal_urinary_system0.75407888
116MP0005367_renal/urinary_system_phenotyp0.75407888
117MP0001529_abnormal_vocalization0.74456451
118MP0003763_abnormal_thymus_physiology0.73575552
119MP0002098_abnormal_vibrissa_morphology0.72778781
120MP0004085_abnormal_heartbeat0.70359973
121MP0002067_abnormal_sensory_capabilities0.69247501
122MP0001919_abnormal_reproductive_system0.69221800
123MP0004782_abnormal_surfactant_physiolog0.67805816
124MP0005375_adipose_tissue_phenotype0.67184001
125MP0005083_abnormal_biliary_tract0.66778097
126MP0002009_preneoplasia0.65753204
127MP0001324_abnormal_eye_pigmentation0.64267975
128MP0002557_abnormal_social/conspecific_i0.64038861
129MP0006276_abnormal_autonomic_nervous0.63554935
130MP0002928_abnormal_bile_duct0.61841563
131MP0001502_abnormal_circadian_rhythm0.61078464
132MP0000579_abnormal_nail_morphology0.58931602
133MP0000470_abnormal_stomach_morphology0.58908263
134MP0005167_abnormal_blood-brain_barrier0.58725804
135MP0001119_abnormal_female_reproductive0.57696346
136MP0002751_abnormal_autonomic_nervous0.57482991
137MP0004484_altered_response_of0.55352936
138MP0001666_abnormal_nutrient_absorption0.53726281
139MP0003119_abnormal_digestive_system0.53425295
140MP0001970_abnormal_pain_threshold0.52251438
141MP0002572_abnormal_emotion/affect_behav0.51289284
142MP0005535_abnormal_body_temperature0.50590715
143MP0000003_abnormal_adipose_tissue0.48561313
144MP0009745_abnormal_behavioral_response0.47785662
145MP0002272_abnormal_nervous_system0.46943483
146MP0003880_abnormal_central_pattern0.46529530
147MP0005623_abnormal_meninges_morphology0.44384263
148MP0004233_abnormal_muscle_weight0.44382129
149MP0003699_abnormal_female_reproductive0.43211713
150MP0001501_abnormal_sleep_pattern0.43074897
151MP0003077_abnormal_cell_cycle0.43067624
152MP0000249_abnormal_blood_vessel0.42597130
153MP0008961_abnormal_basal_metabolism0.42387967
154MP0002734_abnormal_mechanical_nocicepti0.42254384
155MP0001440_abnormal_grooming_behavior0.41404618
156MP0004036_abnormal_muscle_relaxation0.40417629
157MP0003137_abnormal_impulse_conducting0.40056131
158MP0003936_abnormal_reproductive_system0.36225690
159MP0000467_abnormal_esophagus_morphology0.36172005
160MP0003091_abnormal_cell_migration0.35566759
161MP0003635_abnormal_synaptic_transmissio0.31840283
162MP0003631_nervous_system_phenotype0.31150842

Predicted human phenotypes

RankGene SetZ-score
1Absent/shortened dynein arms (HP:0200106)9.83751585
2Dynein arm defect of respiratory motile cilia (HP:0012255)9.83751585
3Severe visual impairment (HP:0001141)8.92506493
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.74381749
5Abnormal respiratory epithelium morphology (HP:0012253)7.31499974
6Abnormal respiratory motile cilium morphology (HP:0005938)7.31499974
7Abnormal respiratory motile cilium physiology (HP:0012261)7.03791343
8Abnormal ciliary motility (HP:0012262)6.43350755
9Bony spicule pigmentary retinopathy (HP:0007737)5.43728160
10Asymmetric septal hypertrophy (HP:0001670)5.07926498
11Rhinitis (HP:0012384)4.87878238
12Resting tremor (HP:0002322)4.65335133
13Chronic bronchitis (HP:0004469)4.60661129
14Bell-shaped thorax (HP:0001591)4.52847177
15Abnormal rod and cone electroretinograms (HP:0008323)4.46066987
16Hyperkalemia (HP:0002153)4.35569764
17Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.26984892
18Potter facies (HP:0002009)4.16723592
19Facial shape deformation (HP:0011334)4.16723592
20Hypoplastic ischia (HP:0003175)4.15852257
21Abnormality of macular pigmentation (HP:0008002)4.01368482
22Infertility (HP:0000789)3.91199232
23Azoospermia (HP:0000027)3.80842567
24Enlarged epiphyses (HP:0010580)3.72426392
25Abnormality of the ischium (HP:0003174)3.68550675
26Nephronophthisis (HP:0000090)3.62958571
27Aplasia/Hypoplasia of the earlobes (HP:0009906)3.43047098
28Bronchiectasis (HP:0002110)3.32669372
29Unilateral renal agenesis (HP:0000122)3.32273418
30Cone-rod dystrophy (HP:0000548)3.31914479
31Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.29856486
32Medial flaring of the eyebrow (HP:0010747)3.21138506
33Abnormality of the renal medulla (HP:0100957)3.14537257
34True hermaphroditism (HP:0010459)3.05038165
35Hypoplasia of the thymus (HP:0000778)3.04985447
36Double outlet right ventricle (HP:0001719)3.01674881
37Congenital malformation of the right heart (HP:0011723)3.01674881
38Postural instability (HP:0002172)2.98238156
39Pancreatic fibrosis (HP:0100732)2.88689548
40Abnormality of the aortic arch (HP:0012303)2.81031105
41Nasal polyposis (HP:0100582)2.78298205
42Pancreatic cysts (HP:0001737)2.75874297
43Abnormality of renal resorption (HP:0011038)2.75153470
44Generalized aminoaciduria (HP:0002909)2.73181963
45Progressive sensorineural hearing impairment (HP:0000408)2.69763342
46Abnormality of the renal cortex (HP:0011035)2.69167900
47Tubulointerstitial nephritis (HP:0001970)2.61257174
48Bronchitis (HP:0012387)2.58100099
49Abnormality of potassium homeostasis (HP:0011042)2.57145517
50Hypoalphalipoproteinemia (HP:0003233)2.51301263
51Decreased central vision (HP:0007663)2.49482606
52Renal cortical cysts (HP:0000803)2.45392105
53Molar tooth sign on MRI (HP:0002419)2.45133006
54Abnormality of midbrain morphology (HP:0002418)2.45133006
55Abnormal spermatogenesis (HP:0008669)2.44212944
56Abnormality of the parathyroid morphology (HP:0011766)2.40369854
57Progressive cerebellar ataxia (HP:0002073)2.38744342
58Abnormality of the costochondral junction (HP:0000919)2.36332891
59Epiphyseal dysplasia (HP:0002656)2.36195576
60Truncal obesity (HP:0001956)2.35331670
61Nephrogenic diabetes insipidus (HP:0009806)2.33789537
62Recurrent sinusitis (HP:0011108)2.32471179
63Chromosomal breakage induced by crosslinking agents (HP:0003221)2.28689547
64Congenital primary aphakia (HP:0007707)2.23592393
65Flattened epiphyses (HP:0003071)2.23490150
66Aplasia/Hypoplasia of the sacrum (HP:0008517)2.21213393
67Absent epiphyses (HP:0010577)2.20096937
68Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.20096937
69Amelogenesis imperfecta (HP:0000705)2.19715962
70Gait imbalance (HP:0002141)2.19525437
71Portal hypertension (HP:0001409)2.16912323
72Ventricular tachycardia (HP:0004756)2.16686991
73Renal Fanconi syndrome (HP:0001994)2.14765931
74Abnormality of dental color (HP:0011073)2.14183689
75Tetany (HP:0001281)2.10629560
76Insulin-resistant diabetes mellitus (HP:0000831)2.09798905
77Postaxial foot polydactyly (HP:0001830)2.08866568
78Abnormality of the nasal mucosa (HP:0000433)2.08475576
79Abnormality of the pubic bones (HP:0003172)2.08325271
80Widely patent fontanelles and sutures (HP:0004492)2.06550933
81Abnormality of the epiphysis of the femoral head (HP:0010574)2.05833350
82Aplasia/Hypoplasia of the lens (HP:0008063)2.05020095
83Hyponatremia (HP:0002902)2.04893753
84Male infertility (HP:0003251)2.03712669
85Congenital hepatic fibrosis (HP:0002612)2.03173334
86Dyschromatopsia (HP:0007641)2.03123420
87Renovascular hypertension (HP:0100817)2.01892566
88Sensory axonal neuropathy (HP:0003390)2.01604739
89Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.01590759
90Median cleft lip (HP:0000161)1.99702772
91Attenuation of retinal blood vessels (HP:0007843)1.98920102
92Abnormality of the renal collecting system (HP:0004742)1.98805034
93Hyperthyroidism (HP:0000836)1.98646973
94Upper limb muscle weakness (HP:0003484)1.98033580
95Spastic paraparesis (HP:0002313)1.97690630
96Acute necrotizing encephalopathy (HP:0006965)1.97478971
97Abnormality of the hepatic vasculature (HP:0006707)1.97007991
98Conjugated hyperbilirubinemia (HP:0002908)1.95594946
99Male pseudohermaphroditism (HP:0000037)1.94426484
100Abnormal ventriculo-arterial connection (HP:0011563)1.94004935
101Transposition of the great arteries (HP:0001669)1.94004935
102Abnormal connection of the cardiac segments (HP:0011545)1.94004935
103Osteomalacia (HP:0002749)1.92340378
104Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.92300629
105Abnormality of femoral epiphyses (HP:0006499)1.92300629
106Increased hepatocellular lipid droplets (HP:0006565)1.91232411
107Duplicated collecting system (HP:0000081)1.90546176
108Menstrual irregularities (HP:0000858)1.90506754
109Renal tubular dysfunction (HP:0000124)1.89464123
110Tubulointerstitial abnormality (HP:0001969)1.88482399
111Flat capital femoral epiphysis (HP:0003370)1.87158611
112Abnormality of renal excretion (HP:0011036)1.86774761
113Chromsome breakage (HP:0040012)1.85732758
114Peripheral hypomyelination (HP:0007182)1.85514160
115Neoplasm of the heart (HP:0100544)1.85226355
116Tubular atrophy (HP:0000092)1.85049159
117Recurrent otitis media (HP:0000403)1.85010462
118Hypoparathyroidism (HP:0000829)1.85006742
119Hypophosphatemic rickets (HP:0004912)1.84768579
120Vaginal atresia (HP:0000148)1.84382024
121Abnormality of the femoral head (HP:0003368)1.82722337
122Genital tract atresia (HP:0001827)1.82383345
12311 pairs of ribs (HP:0000878)1.82024189
124Myokymia (HP:0002411)1.81265987
125Recurrent corneal erosions (HP:0000495)1.79006239
126Recurrent pneumonia (HP:0006532)1.78930856
127Optic nerve hypoplasia (HP:0000609)1.78750106
128Short ribs (HP:0000773)1.78694854
129Polydipsia (HP:0001959)1.78127314
130Abnormal drinking behavior (HP:0030082)1.78127314
131Cystic liver disease (HP:0006706)1.77508144
132Renal dysplasia (HP:0000110)1.74125089
133Impulsivity (HP:0100710)1.71586272
134Type I transferrin isoform profile (HP:0003642)1.71288834
135Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.70286713
136Chronic hepatic failure (HP:0100626)1.69979705
137Facial cleft (HP:0002006)1.69617969
138Abnormality of the dental pulp (HP:0006479)1.68792741
139Optic disc pallor (HP:0000543)1.68615888
140Mitochondrial inheritance (HP:0001427)1.68000842
141Lipid accumulation in hepatocytes (HP:0006561)1.66878571
142Preaxial hand polydactyly (HP:0001177)1.66281416
143Abnormal urine output (HP:0012590)1.66162557
144Hypothermia (HP:0002045)1.64397995
145Poor coordination (HP:0002370)1.61864629
146Polyuria (HP:0000103)1.61619598
147Nephropathy (HP:0000112)1.61608138
1483-Methylglutaconic aciduria (HP:0003535)1.60609491
149Aplasia/Hypoplasia of the tongue (HP:0010295)1.58370557
150Stage 5 chronic kidney disease (HP:0003774)1.57659975
151Abnormality of calcium-phosphate metabolism (HP:0100530)1.56834194
152Occipital encephalocele (HP:0002085)1.56170999
153Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.54346630
154Abnormal protein N-linked glycosylation (HP:0012347)1.54346630
155Abnormal protein glycosylation (HP:0012346)1.54346630
156Abnormal glycosylation (HP:0012345)1.54346630
157Bile duct proliferation (HP:0001408)1.53421332
158Abnormal biliary tract physiology (HP:0012439)1.53421332
159Oligohydramnios (HP:0001562)1.53056398
160Abnormal mitochondria in muscle tissue (HP:0008316)1.52038522
161Symptomatic seizures (HP:0011145)1.51512370
162Absent eyebrow (HP:0002223)1.51145032
163Sclerocornea (HP:0000647)1.51094091
164Exertional dyspnea (HP:0002875)1.50682125
165Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.50605574
166Aplasia/hypoplasia of the uterus (HP:0008684)1.50281018
167Enlarged kidneys (HP:0000105)1.50169249
168Postaxial hand polydactyly (HP:0001162)1.49904497

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR25.31150111
2PDK44.30750116
3PDK34.30750116
4MAP4K23.88141856
5STK383.74465787
6TESK13.56970820
7STK163.37040680
8PDK23.32443724
9PLK22.91286243
10MAPK152.83837220
11BRD42.58168739
12CAMK1G2.18679437
13WNK42.06528929
14STK392.01670911
15NEK61.98923631
16IRAK31.98911134
17IRAK11.96712110
18PRKD31.91705539
19PLK41.89937290
20MST1R1.89634357
21TNIK1.80857436
22CASK1.77554333
23BMPR1B1.74500045
24MUSK1.72294878
25PDPK11.71687714
26ZAK1.69357140
27INSRR1.67932986
28DYRK31.57383394
29PDK11.55110297
30IRAK21.53952959
31BMPR21.42473327
32PNCK1.37860230
33PASK1.37596440
34IRAK41.37254045
35CDK71.36207368
36ICK1.35315310
37MAP3K91.31845322
38TXK1.30664170
39GRK11.24027902
40CDK121.19586357
41PIK3CG1.19097548
42MST41.19060543
43KSR21.12590691
44MAP2K71.10913989
45MAPKAPK51.09645165
46AKT31.07598485
47MKNK11.04698829
48WNK31.04209474
49STK38L1.03666830
50ADRBK21.01180415
51VRK11.00770351
52CHEK20.98161125
53SRPK10.97573884
54LATS20.97084204
55NUAK10.96561889
56DYRK1B0.96151850
57UHMK10.89782280
58BRAF0.88905128
59BUB10.85398758
60PKN10.84768588
61BCR0.84131796
62TTK0.84077667
63MKNK20.83825538
64NME10.83656141
65CDK30.83557142
66YES10.83501672
67NLK0.81209553
68EIF2AK20.79583911
69MAP2K60.79572743
70EPHA20.77699083
71CAMK1D0.76922398
72SIK20.75302563
73GRK70.75067853
74RPS6KA20.74934718
75PRKG20.73910723
76TLK10.73290495
77MAP3K110.72794745
78TEC0.70211314
79PRKG10.70021533
80PRKAA20.69958774
81FRK0.69228558
82DYRK20.69111453
83RPS6KA10.67768393
84PINK10.67727959
85OXSR10.66242414
86MAP3K80.63957554
87PBK0.62888533
88MAP3K20.62337536
89ERBB30.62039787
90MARK10.59876362
91RPS6KA50.59717038
92ROCK10.58388613
93RIPK40.56801712
94MAPK130.54889954
95EIF2AK30.54424507
96CAMK10.53593611
97MYLK0.51621302
98PTK2B0.50152514
99MAP3K140.49719710
100BRSK20.49498734
101GSK3B0.47597522
102CDK40.45872664
103CAMK2B0.45292857
104CDK20.44703915
105CLK10.44413457
106PRKCE0.43524518
107LATS10.43293839
108SGK4940.42108917
109SGK2230.42108917
110BLK0.41248119
111RPS6KL10.41234681
112RPS6KC10.41234681
113MAP3K120.40673268
114CDK10.40173068
115MAPK10.39962848
116TIE10.39936158
117TESK20.39769996
118CSNK2A10.38680542
119RPS6KA60.38669017
120MTOR0.38260274
121AURKA0.37810537
122MAPK80.36846567
123MAP3K10.36805543
124ARAF0.35766121
125PRKCG0.35162044
126MAP2K20.35075897
127CCNB10.35006491
128CAMK40.34804272
129BTK0.33699080
130PRKACA0.33092791
131PRKCZ0.32918313
132CAMK2A0.32636598
133ATR0.32319476
134TYRO30.31886366
135CHEK10.30429844
136CDK80.30267562
137CDK190.29739850
138IKBKE0.28830364
139CAMK2G0.28807915
140WNK10.28705600
141SGK10.28321875
142MET0.28286362
143HIPK20.27578318
144ATM0.27257443
145PLK10.26467204
146PRKCQ0.25957386
147CSNK2A20.25837479
148TAOK30.24484644
149PRKCB0.24451543
150TNK20.24204068
151AURKB0.24026209
152NTRK30.23681392
153MAPK140.23658789
154MAPK100.22413882
155FER0.20006044
156MAPK110.18247812
157AKT10.17074904
158IKBKB0.16859725
159MARK20.16695139
160MAP3K40.14216799
161BRSK10.11213457
162MINK10.10539302
163PRKACB0.10108421
164PRKAA10.08103041
165MAPK90.06135413
166JAK30.05942825
167ACVR1B0.05311168
168PRKCA0.05075463

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.60672832
2Protein export_Homo sapiens_hsa030603.74403886
3Olfactory transduction_Homo sapiens_hsa047403.59885984
4Maturity onset diabetes of the young_Homo sapiens_hsa049503.46244304
5Linoleic acid metabolism_Homo sapiens_hsa005913.27312088
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.11718449
7Butanoate metabolism_Homo sapiens_hsa006502.87219743
8Basal transcription factors_Homo sapiens_hsa030222.40796608
9Oxidative phosphorylation_Homo sapiens_hsa001902.31672860
10Ether lipid metabolism_Homo sapiens_hsa005652.30067366
11Arachidonic acid metabolism_Homo sapiens_hsa005902.15119374
12Sulfur metabolism_Homo sapiens_hsa009202.11366796
13Fanconi anemia pathway_Homo sapiens_hsa034602.05410742
14Type I diabetes mellitus_Homo sapiens_hsa049402.04029433
15RNA polymerase_Homo sapiens_hsa030201.96126823
16Vitamin B6 metabolism_Homo sapiens_hsa007501.94329845
17Sphingolipid metabolism_Homo sapiens_hsa006001.83417390
18Huntingtons disease_Homo sapiens_hsa050161.74302679
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.70645937
20Dorso-ventral axis formation_Homo sapiens_hsa043201.68349819
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67072471
22Other glycan degradation_Homo sapiens_hsa005111.62470732
23Proteasome_Homo sapiens_hsa030501.62224260
24Fatty acid degradation_Homo sapiens_hsa000711.58249583
25Pyrimidine metabolism_Homo sapiens_hsa002401.56127529
26Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.55191461
27Type II diabetes mellitus_Homo sapiens_hsa049301.52912840
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.52323177
29Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.51983416
30Purine metabolism_Homo sapiens_hsa002301.47859332
31Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.44419228
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43039324
33Viral myocarditis_Homo sapiens_hsa054161.42798268
34Parkinsons disease_Homo sapiens_hsa050121.42458819
35Ribosome_Homo sapiens_hsa030101.41353231
36Fatty acid metabolism_Homo sapiens_hsa012121.40670874
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.40159739
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.33678999
39Arginine and proline metabolism_Homo sapiens_hsa003301.31588258
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.30959377
41Collecting duct acid secretion_Homo sapiens_hsa049661.30838076
42Homologous recombination_Homo sapiens_hsa034401.28473454
43Alzheimers disease_Homo sapiens_hsa050101.27145714
44Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.27105584
45Fatty acid biosynthesis_Homo sapiens_hsa000611.24182066
46Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.24142840
47Endocytosis_Homo sapiens_hsa041441.17029322
48RNA transport_Homo sapiens_hsa030131.17000956
49Non-homologous end-joining_Homo sapiens_hsa034501.16901739
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15028106
51Adipocytokine signaling pathway_Homo sapiens_hsa049201.10370585
52Glutathione metabolism_Homo sapiens_hsa004801.10128402
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.09209349
54Phototransduction_Homo sapiens_hsa047441.08319473
55Chemical carcinogenesis_Homo sapiens_hsa052041.06653355
56Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.06652216
57Glycerophospholipid metabolism_Homo sapiens_hsa005641.06620632
58Fatty acid elongation_Homo sapiens_hsa000621.05343726
59Histidine metabolism_Homo sapiens_hsa003401.04573746
60Pentose and glucuronate interconversions_Homo sapiens_hsa000401.04183620
61Steroid hormone biosynthesis_Homo sapiens_hsa001401.03081079
62Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01503807
63Taste transduction_Homo sapiens_hsa047420.98382259
64Fat digestion and absorption_Homo sapiens_hsa049750.97946067
65Salivary secretion_Homo sapiens_hsa049700.96830097
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95743642
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.95453504
68Steroid biosynthesis_Homo sapiens_hsa001000.92039254
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91743903
70Retinol metabolism_Homo sapiens_hsa008300.91251891
71Regulation of autophagy_Homo sapiens_hsa041400.87931794
72PPAR signaling pathway_Homo sapiens_hsa033200.87468482
73Metabolic pathways_Homo sapiens_hsa011000.87214450
74Vibrio cholerae infection_Homo sapiens_hsa051100.86624101
75Autoimmune thyroid disease_Homo sapiens_hsa053200.86300245
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85845977
77Arginine biosynthesis_Homo sapiens_hsa002200.83800479
78Pyruvate metabolism_Homo sapiens_hsa006200.83752427
79ABC transporters_Homo sapiens_hsa020100.83737835
80Inositol phosphate metabolism_Homo sapiens_hsa005620.82091751
81Calcium signaling pathway_Homo sapiens_hsa040200.80428491
82Peroxisome_Homo sapiens_hsa041460.80283076
83Morphine addiction_Homo sapiens_hsa050320.79696187
84Nucleotide excision repair_Homo sapiens_hsa034200.78907828
85cAMP signaling pathway_Homo sapiens_hsa040240.78758521
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.77238719
87Insulin secretion_Homo sapiens_hsa049110.76816864
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75611174
89Influenza A_Homo sapiens_hsa051640.74338727
90Oocyte meiosis_Homo sapiens_hsa041140.72893020
91Vitamin digestion and absorption_Homo sapiens_hsa049770.72735481
92Estrogen signaling pathway_Homo sapiens_hsa049150.72326343
93Circadian entrainment_Homo sapiens_hsa047130.72202609
94Hedgehog signaling pathway_Homo sapiens_hsa043400.71381917
95RNA degradation_Homo sapiens_hsa030180.70027247
96Glycerolipid metabolism_Homo sapiens_hsa005610.69501171
97Synaptic vesicle cycle_Homo sapiens_hsa047210.69440241
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66365185
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66340347
100Mineral absorption_Homo sapiens_hsa049780.63490501
101Folate biosynthesis_Homo sapiens_hsa007900.62546721
102Graft-versus-host disease_Homo sapiens_hsa053320.61459220
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60762428
104Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60756516
105Phenylalanine metabolism_Homo sapiens_hsa003600.59347070
106Nicotine addiction_Homo sapiens_hsa050330.57981681
107Aldosterone synthesis and secretion_Homo sapiens_hsa049250.54639324
108DNA replication_Homo sapiens_hsa030300.54090210
109Rheumatoid arthritis_Homo sapiens_hsa053230.53705848
110Spliceosome_Homo sapiens_hsa030400.53249040
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53237095
112Mismatch repair_Homo sapiens_hsa034300.53040898
113Pancreatic secretion_Homo sapiens_hsa049720.51185930
114Tyrosine metabolism_Homo sapiens_hsa003500.50109391
115Allograft rejection_Homo sapiens_hsa053300.49581788
116Selenocompound metabolism_Homo sapiens_hsa004500.49024366
117Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.48881968
118Renin secretion_Homo sapiens_hsa049240.48712052
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.48243935
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.47750163
121Base excision repair_Homo sapiens_hsa034100.46540787
122Gastric acid secretion_Homo sapiens_hsa049710.46222017
123Bile secretion_Homo sapiens_hsa049760.45517821
124MAPK signaling pathway_Homo sapiens_hsa040100.43977726
125Tight junction_Homo sapiens_hsa045300.43473284
126Glutamatergic synapse_Homo sapiens_hsa047240.43265970
127Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.43259540
128Acute myeloid leukemia_Homo sapiens_hsa052210.41674501
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41208303
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40081590
131Propanoate metabolism_Homo sapiens_hsa006400.39567452
132Cardiac muscle contraction_Homo sapiens_hsa042600.38703452
133Serotonergic synapse_Homo sapiens_hsa047260.38481305
134VEGF signaling pathway_Homo sapiens_hsa043700.36473749
135Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36005622
136Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.35768141
137N-Glycan biosynthesis_Homo sapiens_hsa005100.35425386
138Antigen processing and presentation_Homo sapiens_hsa046120.34702444
139beta-Alanine metabolism_Homo sapiens_hsa004100.33683397
140Glucagon signaling pathway_Homo sapiens_hsa049220.33660049
141Protein digestion and absorption_Homo sapiens_hsa049740.33655408
142Asthma_Homo sapiens_hsa053100.33392412
143Cholinergic synapse_Homo sapiens_hsa047250.32735964
144Ovarian steroidogenesis_Homo sapiens_hsa049130.31878258
145Amphetamine addiction_Homo sapiens_hsa050310.31352336
146Hematopoietic cell lineage_Homo sapiens_hsa046400.31110027
147Viral carcinogenesis_Homo sapiens_hsa052030.31021570
148Renin-angiotensin system_Homo sapiens_hsa046140.30163534
149Drug metabolism - other enzymes_Homo sapiens_hsa009830.29638696
150cGMP-PKG signaling pathway_Homo sapiens_hsa040220.26123812
151Jak-STAT signaling pathway_Homo sapiens_hsa046300.25852413
152Nitrogen metabolism_Homo sapiens_hsa009100.25775515
153GABAergic synapse_Homo sapiens_hsa047270.25109061
154Oxytocin signaling pathway_Homo sapiens_hsa049210.23787579
155mRNA surveillance pathway_Homo sapiens_hsa030150.22513849
156Legionellosis_Homo sapiens_hsa051340.20032270
157ECM-receptor interaction_Homo sapiens_hsa045120.19019173
158Biosynthesis of amino acids_Homo sapiens_hsa012300.18796852
159Herpes simplex infection_Homo sapiens_hsa051680.18719575
160Prolactin signaling pathway_Homo sapiens_hsa049170.18368136
161Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18260047
162Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.16324062
163Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.14628061
164Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.13902626
165Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.13658614
166Long-term potentiation_Homo sapiens_hsa047200.11960035
167Toxoplasmosis_Homo sapiens_hsa051450.11719372

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