FAM193A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)4.14517735
2mitotic sister chromatid cohesion (GO:0007064)4.11988304
3histone H3-K4 trimethylation (GO:0080182)4.00305258
4regulation of acrosome reaction (GO:0060046)3.92245450
5nuclear pore complex assembly (GO:0051292)3.69622684
6negative regulation of cAMP-mediated signaling (GO:0043951)3.60798919
7N-terminal protein amino acid acetylation (GO:0006474)3.56311696
8histone H3-K4 methylation (GO:0051568)3.51244211
9phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.42460592
10DNA methylation involved in gamete generation (GO:0043046)3.38437384
11histone H3-K9 methylation (GO:0051567)3.38303684
12histone H3-K9 demethylation (GO:0033169)3.37726795
13negative regulation of translation, ncRNA-mediated (GO:0040033)3.35477449
14regulation of translation, ncRNA-mediated (GO:0045974)3.35477449
15negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.35477449
16paraxial mesoderm development (GO:0048339)3.33609550
17establishment of protein localization to Golgi (GO:0072600)3.32961815
18peptidyl-lysine trimethylation (GO:0018023)3.30408100
19regulation of female gonad development (GO:2000194)3.27138599
20retrograde transport, vesicle recycling within Golgi (GO:0000301)3.20725883
21kinetochore assembly (GO:0051382)3.18072033
22positive regulation of histone deacetylation (GO:0031065)3.16123228
23positive regulation of CREB transcription factor activity (GO:0032793)3.14287913
24DNA alkylation (GO:0006305)3.13978558
25DNA methylation (GO:0006306)3.13978558
26kinetochore organization (GO:0051383)3.13537687
27pore complex assembly (GO:0046931)3.11115612
28pre-miRNA processing (GO:0031054)3.09890009
29regulation of nuclear cell cycle DNA replication (GO:0033262)3.09305967
30nuclear pore organization (GO:0006999)3.08215318
31regulation of histone H3-K4 methylation (GO:0051569)3.07595186
32negative regulation of DNA-dependent DNA replication (GO:2000104)3.06346015
33histone H4-K12 acetylation (GO:0043983)3.06083117
34interkinetic nuclear migration (GO:0022027)3.05034191
35protein targeting to Golgi (GO:0000042)3.04721411
36histone lysine methylation (GO:0034968)2.99933299
37histone H3-K36 demethylation (GO:0070544)2.98323999
38positive regulation of protein deacetylation (GO:0090312)2.97694968
39regulation of meiosis I (GO:0060631)2.95860077
40synaptonemal complex assembly (GO:0007130)2.95615259
41meiotic chromosome segregation (GO:0045132)2.94009589
42male meiosis (GO:0007140)2.93921843
43oocyte development (GO:0048599)2.92065967
44snRNA transcription (GO:0009301)2.90195563
45regulation of histone methylation (GO:0031060)2.89618965
46multicellular organism reproduction (GO:0032504)2.87233584
47nucleus localization (GO:0051647)2.85535412
48microtubule depolymerization (GO:0007019)2.83984404
49sister chromatid cohesion (GO:0007062)2.80554929
50histone H3-K9 modification (GO:0061647)2.78527717
51cytoplasmic mRNA processing body assembly (GO:0033962)2.76979996
52regulation of histone H3-K27 methylation (GO:0061085)2.76734827
53pattern specification involved in kidney development (GO:0061004)2.74276187
54insulin-like growth factor receptor signaling pathway (GO:0048009)2.73614703
55histone H2A acetylation (GO:0043968)2.72808893
56DNA methylation or demethylation (GO:0044728)2.70758629
57gene silencing by RNA (GO:0031047)2.69349492
58DNA double-strand break processing (GO:0000729)2.68444992
59synaptonemal complex organization (GO:0070193)2.65968811
60gene silencing (GO:0016458)2.63415947
61microtubule nucleation (GO:0007020)2.63293750
62centriole replication (GO:0007099)2.63063132
63protein polyglutamylation (GO:0018095)2.62896748
64negative regulation of histone modification (GO:0031057)2.62834228
65regulation of protein deacetylation (GO:0090311)2.61209866
66histone lysine demethylation (GO:0070076)2.59852302
67positive regulation of granulocyte differentiation (GO:0030854)2.59605172
68myelin assembly (GO:0032288)2.57625697
69histone methylation (GO:0016571)2.55435903
70regulation of nucleobase-containing compound transport (GO:0032239)2.54218433
71stress granule assembly (GO:0034063)2.53314849
72positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.52964593
73positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.52964593
74positive regulation of mitotic sister chromatid separation (GO:1901970)2.52964593
75regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.51397457
76positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.51397457
77histone demethylation (GO:0016577)2.51266863
78DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.50808896
79regulation of ARF GTPase activity (GO:0032312)2.49025907
80regulation of mitotic spindle checkpoint (GO:1903504)2.49015274
81regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.49015274
82regulation of Rab GTPase activity (GO:0032313)2.48668248
83positive regulation of Rab GTPase activity (GO:0032851)2.48668248
84centriole assembly (GO:0098534)2.48370855
85establishment of nucleus localization (GO:0040023)2.47815171
86negative regulation of histone methylation (GO:0031061)2.47184552
87regulation of telomere maintenance via telomerase (GO:0032210)2.46776784
88positive regulation of DNA-dependent DNA replication (GO:2000105)2.46383040
89regulation of histone deacetylation (GO:0031063)2.45174420
90monoubiquitinated protein deubiquitination (GO:0035520)2.44055267
91histone H4-K16 acetylation (GO:0043984)2.43293226
92chromosome organization involved in meiosis (GO:0070192)2.43164343
93regulation of centriole replication (GO:0046599)2.42828017
94negative regulation of chromatin modification (GO:1903309)2.42114554
95oogenesis (GO:0048477)2.40840626
96positive regulation of mRNA 3-end processing (GO:0031442)2.40835354
97positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.39159920
98regulation of RNA export from nucleus (GO:0046831)2.39004924
99protein demethylation (GO:0006482)2.38085954
100protein dealkylation (GO:0008214)2.38085954
101replicative senescence (GO:0090399)2.37983567
102female gamete generation (GO:0007292)2.35542587
103negative regulation of fibroblast apoptotic process (GO:2000270)2.35514416
104chromatin silencing (GO:0006342)2.34432232
105regulation of telomere maintenance (GO:0032204)2.34281252
106histone H4-K5 acetylation (GO:0043981)2.33408979
107histone H4-K8 acetylation (GO:0043982)2.33408979
108DNA damage induced protein phosphorylation (GO:0006975)2.32785956
109DNA damage response, signal transduction resulting in transcription (GO:0042772)2.32147453
110positive regulation by host of viral transcription (GO:0043923)2.32134089
111protein localization to microtubule cytoskeleton (GO:0072698)2.31930036
112regulation of gene expression, epigenetic (GO:0040029)2.30664909
113activated T cell proliferation (GO:0050798)2.28259099
114regulation of histone H3-K9 methylation (GO:0051570)2.28010540
115positive regulation of macroautophagy (GO:0016239)2.27120605
116peptidyl-lysine methylation (GO:0018022)2.27057351
117regulation of gene expression by genetic imprinting (GO:0006349)2.26905500
118DNA modification (GO:0006304)2.26588927
119vesicle transport along microtubule (GO:0047496)2.26542428
120epithelial cell fate commitment (GO:0072148)2.26310698
121positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.24809249
122regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.24809249
123negative regulation of gene expression, epigenetic (GO:0045814)2.22564654
124olfactory bulb development (GO:0021772)2.22305326
125peptidyl-threonine phosphorylation (GO:0018107)2.22136494
126peptidyl-lysine dimethylation (GO:0018027)2.21748939
127regulation of ARF protein signal transduction (GO:0032012)2.21575385
128head development (GO:0060322)2.21562961
129regulation of sister chromatid cohesion (GO:0007063)2.21482585
130intracellular estrogen receptor signaling pathway (GO:0030520)2.21452855
131histone H4 acetylation (GO:0043967)2.21074825
132meiotic cell cycle (GO:0051321)2.21022096
133attachment of spindle microtubules to kinetochore (GO:0008608)2.20670924
134protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.20366477
135maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.19843563
136Golgi to endosome transport (GO:0006895)2.19399343
137positive regulation of gene expression, epigenetic (GO:0045815)2.19189677
138regulation of mitotic metaphase/anaphase transition (GO:0030071)2.18921363
139regulation of mRNA 3-end processing (GO:0031440)2.18893975
140regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.18831623
141maintenance of protein location in nucleus (GO:0051457)2.18616683
142positive regulation of meiosis (GO:0045836)2.18551019
143RNA destabilization (GO:0050779)2.18138469
144meiotic nuclear division (GO:0007126)2.18124849
145histone acetylation (GO:0016573)2.18104822
146notochord development (GO:0030903)2.18008254
147tachykinin receptor signaling pathway (GO:0007217)2.17872585
148female gonad development (GO:0008585)2.17510121
149DNA synthesis involved in DNA repair (GO:0000731)2.16867949
150negative regulation of granulocyte differentiation (GO:0030853)2.16793305
151mRNA splice site selection (GO:0006376)2.16101549
152regulation of protein polyubiquitination (GO:1902914)2.14225717
153replication fork processing (GO:0031297)2.14095648
154microtubule anchoring (GO:0034453)2.14007749
155regulation of granulocyte differentiation (GO:0030852)2.13945203
156histone deubiquitination (GO:0016578)2.13595342
157histone H4 deacetylation (GO:0070933)2.13135103
158NLS-bearing protein import into nucleus (GO:0006607)2.12446887
159positive regulation of humoral immune response (GO:0002922)2.11370498
160regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.11302962
161regulation of DNA methylation (GO:0044030)2.11187419
162histone H3 deacetylation (GO:0070932)2.10991260
163positive regulation of gamma-delta T cell activation (GO:0046645)2.07631448
164protein localization to Golgi apparatus (GO:0034067)2.07455735
165acrosome reaction (GO:0007340)2.06821994

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.41835994
2TP63_19390658_ChIP-ChIP_HaCaT_Human4.22738173
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.81462491
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.23750507
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.83978184
6DROSHA_22980978_ChIP-Seq_HELA_Human2.57018316
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.54017018
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.42670242
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.33068024
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.18114322
11EZH2_22144423_ChIP-Seq_EOC_Human2.15479406
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.12331895
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.01813289
14* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.01513898
15GBX2_23144817_ChIP-Seq_PC3_Human1.91360752
16RBPJ_22232070_ChIP-Seq_NCS_Mouse1.90633407
17EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88640826
18KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.86082673
19SCL_19346495_ChIP-Seq_HPC-7_Human1.82521130
20TCF7_22412390_ChIP-Seq_EML_Mouse1.79698491
21BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.79197941
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.79076524
23HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.78138314
24TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75099482
25POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.75099482
26AR_21572438_ChIP-Seq_LNCaP_Human1.74009004
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.73954331
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.65891792
29FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.64590508
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60611975
31FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.60585007
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.60557773
33FUS_26573619_Chip-Seq_HEK293_Human1.60542422
34MYC_22102868_ChIP-Seq_BL_Human1.60541577
35EWS_26573619_Chip-Seq_HEK293_Human1.55789713
36* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.54234644
37KDM2B_26808549_Chip-Seq_DND41_Human1.53547089
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.52341343
39STAT6_21828071_ChIP-Seq_BEAS2B_Human1.51149716
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50971567
41CIITA_25753668_ChIP-Seq_RAJI_Human1.47253761
42CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43800704
43GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.43141928
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42082684
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41808143
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40856874
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.40180635
48TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38704790
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38518307
50TP53_16413492_ChIP-PET_HCT116_Human1.38291124
51VDR_24787735_ChIP-Seq_THP-1_Human1.38179064
52DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.37579914
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37212749
54KDM2B_26808549_Chip-Seq_K562_Human1.37065044
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.36828330
56FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.36081713
57RUNX_20019798_ChIP-Seq_JUKART_Human1.34111382
58GATA1_26923725_Chip-Seq_HPCs_Mouse1.31744172
59RNF2_27304074_Chip-Seq_NSC_Mouse1.28721546
60SPI1_23127762_ChIP-Seq_K562_Human1.28710797
61KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.27966857
62CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.27040386
63* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26601584
64PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.25728783
65* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.25704379
66NANOG_18555785_Chip-Seq_ESCs_Mouse1.24482734
67E2F1_21310950_ChIP-Seq_MCF-7_Human1.23391379
68STAT3_23295773_ChIP-Seq_U87_Human1.22974087
69CTNNB1_20460455_ChIP-Seq_HCT116_Human1.22766527
70* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.22664091
71TCF4_23295773_ChIP-Seq_U87_Human1.21965392
72ZNF274_21170338_ChIP-Seq_K562_Hela1.21563410
73E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.20879757
74ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20799742
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.20170513
76POU5F1_16153702_ChIP-ChIP_HESCs_Human1.19984146
77PKCTHETA_26484144_Chip-Seq_BREAST_Human1.18988300
78RNF2_27304074_Chip-Seq_ESCs_Mouse1.17501937
79CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.17501357
80ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15802216
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15699932
82SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15465997
83GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14903429
84EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.13999745
85* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13885016
86VDR_21846776_ChIP-Seq_THP-1_Human1.13081212
87ISL1_27105846_Chip-Seq_CPCs_Mouse1.12626971
88ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12616939
89IGF1R_20145208_ChIP-Seq_DFB_Human1.11069465
90* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10520355
91SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10511719
92AR_19668381_ChIP-Seq_PC3_Human1.10199687
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.09850833
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.08637735
95NFE2_27457419_Chip-Seq_LIVER_Mouse1.08381195
96JARID2_20064375_ChIP-Seq_MESCs_Mouse1.08245712
97SMAD4_21799915_ChIP-Seq_A2780_Human1.07251093
98EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05083502
99EZH2_27304074_Chip-Seq_ESCs_Mouse1.04168455
100STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.03085959
101REST_21632747_ChIP-Seq_MESCs_Mouse1.02863939
102TBX3_20139965_ChIP-Seq_ESCs_Mouse1.02505819
103NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.02394435
104P300_19829295_ChIP-Seq_ESCs_Human1.02326920
105LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01655972
106TBL1_22424771_ChIP-Seq_293T_Human1.01626160
107YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01365217
108ELK4_26923725_Chip-Seq_MESODERM_Mouse1.00341732
109TBX3_20139965_ChIP-Seq_MESCs_Mouse1.00268630
110RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99961760
111GATA1_19941827_ChIP-Seq_MEL_Mouse0.99613834
112OCT4_19829295_ChIP-Seq_ESCs_Human0.99553046
113FOXA2_19822575_ChIP-Seq_HepG2_Human0.98510573
114P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97694900
115RUNX1_26923725_Chip-Seq_HPCs_Mouse0.97509838
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.97366378
117ZNF217_24962896_ChIP-Seq_MCF-7_Human0.97025022
118BCAT_22108803_ChIP-Seq_LS180_Human0.96362771
119VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95839864
120BMI1_23680149_ChIP-Seq_NPCS_Mouse0.95428341
121GF1B_26923725_Chip-Seq_HPCs_Mouse0.95120001
122SMRT_27268052_Chip-Seq_Bcells_Human0.94139244
123TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93442549
124PCGF2_27294783_Chip-Seq_NPCs_Mouse0.93361570
125EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.92546957
126JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92517891
127SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92514743
128TCF4_18268006_ChIP-ChIP_LS174T_Human0.91975912
129SOX9_26525672_Chip-Seq_HEART_Mouse0.91915328
130TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91638931
131BRD4_25478319_ChIP-Seq_HGPS_Human0.91208813
132RARB_27405468_Chip-Seq_BRAIN_Mouse0.88894417
133ER_23166858_ChIP-Seq_MCF-7_Human0.88678677
134MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88595881
135PRDM14_20953172_ChIP-Seq_ESCs_Human0.88146766
136EZH2_27294783_Chip-Seq_NPCs_Mouse0.87623051
137SMAD3_21741376_ChIP-Seq_EPCs_Human0.87566148
138NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87442554
139P53_22387025_ChIP-Seq_ESCs_Mouse0.87216648
140STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.86977032
141CMYC_18555785_Chip-Seq_ESCs_Mouse0.86664867
142VDR_24763502_ChIP-Seq_THP-1_Human0.85660251
143GATA1_19941826_ChIP-Seq_K562_Human0.85604267
144ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85471907
145SOX2_21211035_ChIP-Seq_LN229_Gbm0.85335244
146GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84704794
147MITF_21258399_ChIP-Seq_MELANOMA_Human0.84252515
148STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.84220990
149GATA2_19941826_ChIP-Seq_K562_Human0.84213971
150TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83945670
151AHR_22903824_ChIP-Seq_MCF-7_Human0.83570749
152NOTCH1_21737748_ChIP-Seq_TLL_Human0.82886137
153FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.82883700
154KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.82676199
155STAT3_18555785_Chip-Seq_ESCs_Mouse0.82578679
156ARNT_22903824_ChIP-Seq_MCF-7_Human0.82309242
157KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.79912422

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.25291205
2MP0008877_abnormal_DNA_methylation3.81779794
3MP0003787_abnormal_imprinting3.30935150
4MP0008057_abnormal_DNA_replication2.98625041
5MP0003121_genomic_imprinting2.75893027
6MP0009278_abnormal_bone_marrow2.52041170
7MP0006292_abnormal_olfactory_placode2.48493948
8MP0003646_muscle_fatigue2.44704753
9MP0000566_synostosis2.44671728
10MP0008058_abnormal_DNA_repair2.22519822
11MP0010094_abnormal_chromosome_stability2.20716728
12MP0003111_abnormal_nucleus_morphology2.19252863
13MP0003172_abnormal_lysosome_physiology2.16475433
14MP0005397_hematopoietic_system_phenotyp2.08963681
15MP0001545_abnormal_hematopoietic_system2.08963681
16MP0004858_abnormal_nervous_system1.97638842
17MP0008007_abnormal_cellular_replicative1.93605099
18MP0009780_abnormal_chondrocyte_physiolo1.79523677
19MP0003077_abnormal_cell_cycle1.79490954
20MP0003122_maternal_imprinting1.74367743
21MP0005310_abnormal_salivary_gland1.69024090
22MP0010030_abnormal_orbit_morphology1.68564547
23MP0003890_abnormal_embryonic-extraembry1.66559292
24MP0001501_abnormal_sleep_pattern1.64277675
25MP0008995_early_reproductive_senescence1.63242387
26MP0003693_abnormal_embryo_hatching1.58613551
27MP0001986_abnormal_taste_sensitivity1.57443329
28MP0002653_abnormal_ependyma_morphology1.55191545
29MP0005409_darkened_coat_color1.50494447
30MP0001502_abnormal_circadian_rhythm1.47784184
31MP0001188_hyperpigmentation1.47215891
32MP0008961_abnormal_basal_metabolism1.46598557
33MP0002063_abnormal_learning/memory/cond1.41064985
34MP0003937_abnormal_limbs/digits/tail_de1.38439063
35MP0000015_abnormal_ear_pigmentation1.37966939
36MP0002102_abnormal_ear_morphology1.34612061
37MP0005257_abnormal_intraocular_pressure1.34270109
38MP0002168_other_aberrant_phenotype1.34194002
39MP0002210_abnormal_sex_determination1.31555245
40MP0003755_abnormal_palate_morphology1.28064633
41MP0005174_abnormal_tail_pigmentation1.27341730
42MP0000049_abnormal_middle_ear1.27323416
43MP0002396_abnormal_hematopoietic_system1.26569248
44MP0002249_abnormal_larynx_morphology1.25910829
45MP0002138_abnormal_hepatobiliary_system1.25741489
46MP0005076_abnormal_cell_differentiation1.25528828
47MP0004381_abnormal_hair_follicle1.25515436
48MP0003879_abnormal_hair_cell1.23212208
49MP0002876_abnormal_thyroid_physiology1.23190658
50MP0002735_abnormal_chemical_nociception1.23173232
51MP0003935_abnormal_craniofacial_develop1.22631461
52MP0000432_abnormal_head_morphology1.22393527
53MP0001929_abnormal_gametogenesis1.22265004
54MP0002938_white_spotting1.21351035
55MP0002116_abnormal_craniofacial_bone1.21250453
56MP0006072_abnormal_retinal_apoptosis1.20878798
57MP0001293_anophthalmia1.19021065
58MP0009046_muscle_twitch1.16202532
59MP0010368_abnormal_lymphatic_system1.14641185
60MP0005386_behavior/neurological_phenoty1.14009795
61MP0004924_abnormal_behavior1.14009795
62MP0000470_abnormal_stomach_morphology1.13699488
63MP0000733_abnormal_muscle_development1.13667368
64MP0009115_abnormal_fat_cell1.13310517
65MP0003763_abnormal_thymus_physiology1.13024281
66MP0009250_abnormal_appendicular_skeleto1.09211110
67MP0009703_decreased_birth_body1.08776626
68MP0003385_abnormal_body_wall1.08359838
69MP0002822_catalepsy1.08246779
70MP0000350_abnormal_cell_proliferation1.06940196
71MP0003698_abnormal_male_reproductive1.05579371
72MP0003786_premature_aging1.04602781
73MP0001286_abnormal_eye_development1.04527989
74MP0003878_abnormal_ear_physiology1.04110508
75MP0005377_hearing/vestibular/ear_phenot1.04110508
76MP0003941_abnormal_skin_development1.03168058
77MP0003942_abnormal_urinary_system1.02498847
78MP0000428_abnormal_craniofacial_morphol1.00954450
79MP0002085_abnormal_embryonic_tissue0.99950391
80MP0005171_absent_coat_pigmentation0.99715681
81MP0002084_abnormal_developmental_patter0.99107285
82MP0001145_abnormal_male_reproductive0.98817478
83MP0000653_abnormal_sex_gland0.97870422
84MP0000778_abnormal_nervous_system0.97091632
85MP0008932_abnormal_embryonic_tissue0.96909339
86MP0003303_peritoneal_inflammation0.95830364
87MP0005551_abnormal_eye_electrophysiolog0.95088881
88MP0005253_abnormal_eye_physiology0.94378596
89MP0002557_abnormal_social/conspecific_i0.94070484
90MP0003861_abnormal_nervous_system0.94014017
91MP0001672_abnormal_embryogenesis/_devel0.93828130
92MP0005380_embryogenesis_phenotype0.93828130
93MP0004859_abnormal_synaptic_plasticity0.93407823
94MP0004134_abnormal_chest_morphology0.92988806
95MP0001800_abnormal_humoral_immune0.92496545
96MP0003115_abnormal_respiratory_system0.91564585
97MP0005248_abnormal_Harderian_gland0.91320563
98MP0004808_abnormal_hematopoietic_stem0.90621102
99MP0002572_abnormal_emotion/affect_behav0.88964140
100MP0005394_taste/olfaction_phenotype0.88853360
101MP0005499_abnormal_olfactory_system0.88853360
102MP0003045_fibrosis0.88670654
103MP0000955_abnormal_spinal_cord0.88606123
104MP0002075_abnormal_coat/hair_pigmentati0.88578700
105MP0008789_abnormal_olfactory_epithelium0.87550592
106MP0002109_abnormal_limb_morphology0.87434470
107MP0003635_abnormal_synaptic_transmissio0.86443798
108MP0002152_abnormal_brain_morphology0.86304302
109MP0003984_embryonic_growth_retardation0.85952095
110MP0000703_abnormal_thymus_morphology0.85251042
111MP0002163_abnormal_gland_morphology0.84151903
112MP0002127_abnormal_cardiovascular_syste0.83888293
113MP0005508_abnormal_skeleton_morphology0.83796016
114MP0002088_abnormal_embryonic_growth/wei0.83347600
115MP0003183_abnormal_peptide_metabolism0.82949527
116MP0005670_abnormal_white_adipose0.82943664
117MP0001119_abnormal_female_reproductive0.82737254
118MP0003943_abnormal_hepatobiliary_system0.82139822
119MP0005391_vision/eye_phenotype0.81917170
120MP0005075_abnormal_melanosome_morpholog0.81699233
121MP0002114_abnormal_axial_skeleton0.81569209
122MP0001186_pigmentation_phenotype0.81457734
123MP0005387_immune_system_phenotype0.80422241
124MP0001790_abnormal_immune_system0.80422241
125MP0005645_abnormal_hypothalamus_physiol0.80181403
126MP0005503_abnormal_tendon_morphology0.79710327
127MP0003123_paternal_imprinting0.79290560
128MP0003091_abnormal_cell_migration0.78865747
129MP0000685_abnormal_immune_system0.78361906
130MP0002233_abnormal_nose_morphology0.78230360
131MP0003436_decreased_susceptibility_to0.77735479
132MP0004197_abnormal_fetal_growth/weight/0.77240208
133MP0001697_abnormal_embryo_size0.76593689
134MP0002882_abnormal_neuron_morphology0.76437723
135MP0001324_abnormal_eye_pigmentation0.75800388
136MP0002398_abnormal_bone_marrow0.75738090
137MP0002177_abnormal_outer_ear0.75683763
138MP0002009_preneoplasia0.75214507
139MP0002932_abnormal_joint_morphology0.75129247
140MP0001486_abnormal_startle_reflex0.73877120
141MP0003631_nervous_system_phenotype0.73759301
142MP0004811_abnormal_neuron_physiology0.73388802
143MP0003632_abnormal_nervous_system0.72472924
144MP0005395_other_phenotype0.72056960
145MP0003567_abnormal_fetal_cardiomyocyte0.71721016
146MP0000383_abnormal_hair_follicle0.71573897
147MP0010307_abnormal_tumor_latency0.71449227
148MP0000371_diluted_coat_color0.71356146
149MP0000681_abnormal_thyroid_gland0.70982987
150MP0002925_abnormal_cardiovascular_devel0.70472535
151MP0001299_abnormal_eye_distance/0.70457391
152MP0003699_abnormal_female_reproductive0.70300146
153MP0001270_distended_abdomen0.69647319
154MP0000516_abnormal_urinary_system0.69477056
155MP0005367_renal/urinary_system_phenotyp0.69477056
156MP0003656_abnormal_erythrocyte_physiolo0.69222692
157MP0003950_abnormal_plasma_membrane0.68043545
158MP0002697_abnormal_eye_size0.67662058
159MP0000631_abnormal_neuroendocrine_gland0.67155395
160MP0002161_abnormal_fertility/fecundity0.66568450

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)3.67106327
2Protruding tongue (HP:0010808)3.64087187
3Chromsome breakage (HP:0040012)3.42628798
4Abnormality of the fingertips (HP:0001211)3.39938213
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.23722512
6Deep palmar crease (HP:0006191)3.09465126
7Hyperkalemia (HP:0002153)3.01202233
8Volvulus (HP:0002580)2.97822914
9Ectopic kidney (HP:0000086)2.91704853
10Abnormality of the nasal septum (HP:0000419)2.87424916
11Long eyelashes (HP:0000527)2.69113089
12Short 4th metacarpal (HP:0010044)2.59770942
13Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.59770942
14Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.59249228
15Hypoplastic iliac wings (HP:0002866)2.56989773
16Midline defect of the nose (HP:0004122)2.56187538
17Supernumerary ribs (HP:0005815)2.52313231
18Prostate neoplasm (HP:0100787)2.47733013
19Urethral obstruction (HP:0000796)2.46483617
20Abnormality of the aortic arch (HP:0012303)2.46067595
21Hyperventilation (HP:0002883)2.44040068
22Gaze-evoked nystagmus (HP:0000640)2.41458671
23Tented upper lip vermilion (HP:0010804)2.38028433
24Hypoplastic ischia (HP:0003175)2.37053323
25Trigonocephaly (HP:0000243)2.34496684
26Abnormality of the incisor (HP:0000676)2.29189145
27Supernumerary bones of the axial skeleton (HP:0009144)2.28422071
28Renovascular hypertension (HP:0100817)2.27679808
29Tapered finger (HP:0001182)2.25803317
30Lip pit (HP:0100267)2.25236430
31Dysmetric saccades (HP:0000641)2.24867168
32Abnormality of the labia minora (HP:0012880)2.21464057
33Abnormality of incisor morphology (HP:0011063)2.21135119
34Papillary thyroid carcinoma (HP:0002895)2.18782153
35Thick eyebrow (HP:0000574)2.18235216
36Stomach cancer (HP:0012126)2.17670634
37Absent frontal sinuses (HP:0002688)2.17268680
38Congenital stationary night blindness (HP:0007642)2.14962207
39Abnormal hair whorl (HP:0010721)2.13091538
40Increased number of teeth (HP:0011069)2.12188251
41Abnormal number of incisors (HP:0011064)2.11777297
42Anal stenosis (HP:0002025)2.11344573
43Abnormality of the parietal bone (HP:0002696)2.08907680
44Hyperacusis (HP:0010780)2.07209651
45Abnormality of the columella (HP:0009929)2.05932405
46Febrile seizures (HP:0002373)2.03069396
47Narrow palate (HP:0000189)2.02354244
48Abnormality of the ischium (HP:0003174)2.00235311
49Oligodactyly (hands) (HP:0001180)1.98438071
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.97325902
51Broad face (HP:0000283)1.97291028
52Cerebral aneurysm (HP:0004944)1.97088451
53Broad alveolar ridges (HP:0000187)1.97084687
54Abnormality of chromosome stability (HP:0003220)1.96865079
55Laryngomalacia (HP:0001601)1.96627944
56Progressive cerebellar ataxia (HP:0002073)1.94736675
57Aplasia/Hypoplasia of the uvula (HP:0010293)1.94539820
58Impulsivity (HP:0100710)1.94337123
59Abnormality of the parathyroid morphology (HP:0011766)1.94223420
60Aplasia/Hypoplasia of the earlobes (HP:0009906)1.92919218
61Hip dysplasia (HP:0001385)1.90492559
62Chin dimple (HP:0010751)1.88776785
63Deep philtrum (HP:0002002)1.85614814
64Patellar aplasia (HP:0006443)1.85510293
65Prominent nose (HP:0000448)1.85099191
66Small hand (HP:0200055)1.83999749
67Tubulointerstitial nephritis (HP:0001970)1.83893461
68Broad-based gait (HP:0002136)1.83299004
69Intestinal atresia (HP:0011100)1.83179050
70Abnormality of the intervertebral disk (HP:0005108)1.82531218
71Heterotopia (HP:0002282)1.81635078
72Chronic hepatic failure (HP:0100626)1.80397455
73Congenital malformation of the right heart (HP:0011723)1.80005878
74Double outlet right ventricle (HP:0001719)1.80005878
75Meckel diverticulum (HP:0002245)1.79665364
76Acute lymphatic leukemia (HP:0006721)1.78853159
77Abnormality of chromosome segregation (HP:0002916)1.78479128
78Neoplasm of the oral cavity (HP:0100649)1.78261740
79Increased nuchal translucency (HP:0010880)1.77980828
80Abnormality of lateral ventricle (HP:0030047)1.77687499
81Medulloblastoma (HP:0002885)1.77477061
82Hypoplasia of the maxilla (HP:0000327)1.76451288
83Nephroblastoma (Wilms tumor) (HP:0002667)1.76289873
84Birth length less than 3rd percentile (HP:0003561)1.75847806
85Sandal gap (HP:0001852)1.75318834
86Neoplasm of the adrenal cortex (HP:0100641)1.75157722
87Truncal obesity (HP:0001956)1.74426985
88Exotropia (HP:0000577)1.73437687
89Spinal cord lesions (HP:0100561)1.72427753
90Syringomyelia (HP:0003396)1.72427753
91Decreased circulating renin level (HP:0003351)1.71997922
92Abnormality of the ileum (HP:0001549)1.71609124
93Acute myeloid leukemia (HP:0004808)1.71009785
94Embryonal renal neoplasm (HP:0011794)1.70958343
95Stereotypic behavior (HP:0000733)1.70058015
96Widely spaced teeth (HP:0000687)1.69913666
97Rib fusion (HP:0000902)1.69809742
98Highly arched eyebrow (HP:0002553)1.68399626
99High anterior hairline (HP:0009890)1.68086133
100Clubbing of toes (HP:0100760)1.67104900
101Aplasia/Hypoplasia of the patella (HP:0006498)1.66916873
102Bony spicule pigmentary retinopathy (HP:0007737)1.66867798
103Autism (HP:0000717)1.66755638
104Drooling (HP:0002307)1.66434601
105Facial hemangioma (HP:0000329)1.65525779
106Microtia (HP:0008551)1.65247029
107Short middle phalanx of the 5th finger (HP:0004220)1.65030906
108Glioma (HP:0009733)1.64731196
109Aplasia cutis congenita (HP:0001057)1.64500324
110Shawl scrotum (HP:0000049)1.63975234
111Low anterior hairline (HP:0000294)1.63583027
112Abnormality of the carotid arteries (HP:0005344)1.63501189
113Skull defect (HP:0001362)1.63241471
114Excessive salivation (HP:0003781)1.62870183
115Precocious puberty (HP:0000826)1.62579740
116Genetic anticipation (HP:0003743)1.62069973
117Oligodactyly (HP:0012165)1.61766328
118Obsessive-compulsive behavior (HP:0000722)1.60959764
119Aqueductal stenosis (HP:0002410)1.60572291
120Postural instability (HP:0002172)1.60356483
121Neoplasm of the tracheobronchial system (HP:0100552)1.59708748
122Lymphangioma (HP:0100764)1.59058077
123Intestinal fistula (HP:0100819)1.58661429
124Diastasis recti (HP:0001540)1.58451451
125Dynein arm defect of respiratory motile cilia (HP:0012255)1.58384105
126Absent/shortened dynein arms (HP:0200106)1.58384105
127Aplasia/Hypoplasia of the sternum (HP:0006714)1.58312212
128Macroglossia (HP:0000158)1.58305860
129Convex nasal ridge (HP:0000444)1.57862659
130Dislocated radial head (HP:0003083)1.57558260
131Depressed nasal tip (HP:0000437)1.56840689
132Spondylolisthesis (HP:0003302)1.56445734
133Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.56108969
134Cubitus valgus (HP:0002967)1.55912162
135Abnormality of the right ventricle (HP:0001707)1.55884982
136Hypochromic microcytic anemia (HP:0004840)1.55350808
137Bell-shaped thorax (HP:0001591)1.55077502
138Broad thumb (HP:0011304)1.55022079
139Tracheomalacia (HP:0002779)1.54685811
140Neonatal hypoglycemia (HP:0001998)1.54545272
141Nephronophthisis (HP:0000090)1.54294500
142Broad finger (HP:0001500)1.54011605
143Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.53859149
144Oligodontia (HP:0000677)1.53590720
145Hypoplastic labia majora (HP:0000059)1.53547671
146Spontaneous hematomas (HP:0007420)1.53406584
147Short philtrum (HP:0000322)1.52963887
148Sparse lateral eyebrow (HP:0005338)1.52131093
149Abnormality of the radial head (HP:0003995)1.51187130
150Uterine leiomyosarcoma (HP:0002891)1.51184549
151Leiomyosarcoma (HP:0100243)1.51184549
152Spinal muscular atrophy (HP:0007269)1.50730820
153Visual hallucinations (HP:0002367)1.50670630
154Abnormality of the 4th metacarpal (HP:0010012)1.50498879
155Macroorchidism (HP:0000053)1.50417311
156Abnormality of abdominal situs (HP:0011620)1.50330688
157Abdominal situs inversus (HP:0003363)1.50330688
158Clumsiness (HP:0002312)1.50156876
159Downturned corners of mouth (HP:0002714)1.49631703
160Abnormality of homocysteine metabolism (HP:0010919)1.47773111
161Homocystinuria (HP:0002156)1.47773111
162Abnormality of midbrain morphology (HP:0002418)1.47736447
163Molar tooth sign on MRI (HP:0002419)1.47736447
164Broad phalanges of the hand (HP:0009768)1.47562213
165Abnormality of the phalanges of the hallux (HP:0010057)1.47532487

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.92908498
2BRD43.31592625
3PLK42.82878807
4LATS12.67472746
5CDC72.45359715
6CAMK1G2.42237179
7TAOK12.29233384
8NUAK12.26062986
9MAP3K92.18508478
10ZAK2.17945416
11FRK2.17422746
12CAMK1D2.11963198
13TRIB32.06837830
14CASK1.99514120
15MKNK21.92378142
16TNK21.87434372
17BMPR21.81859618
18BMPR1B1.81482901
19TTK1.78489986
20PNCK1.78364540
21CDK91.71424467
22CHEK21.71414599
23ATR1.60776993
24MAP3K71.60408705
25MAP3K61.58754152
26ICK1.56300618
27SRPK11.54687707
28STK31.53045183
29DMPK1.51692847
30MELK1.51100210
31STK38L1.42978718
32NEK21.35746687
33IRAK41.34538451
34IRAK31.33495783
35PKN21.30017634
36ATM1.24934488
37CDK31.24899960
38CDK81.23404535
39CHUK1.22472777
40MKNK11.21172172
41MARK11.20496964
42LATS21.17830569
43CAMK41.12112785
44MAPK131.11913795
45SIK31.11799313
46TAOK31.11367194
47HIPK21.09000823
48CHEK11.07452612
49EIF2AK21.06773135
50MAP4K11.06679418
51PLK11.06162798
52TYRO31.05234261
53MTOR1.04037504
54NTRK21.01740078
55CAMK11.01127067
56NTRK30.98733026
57AKT30.98107912
58EEF2K0.96641128
59CDC42BPA0.94987440
60SGK20.94608010
61CDK70.92429763
62CLK10.92326317
63RIPK40.92289990
64EPHA30.91537352
65PLK30.85487245
66SIK20.85399186
67PRPF4B0.81253752
68STK110.80950262
69STK380.80037869
70WNK10.79720456
71IRAK20.79176936
72CDK20.78902300
73CDK10.78498497
74ACVR1B0.77046187
75ERBB30.76680449
76MARK20.76604940
77PRKCH0.76342806
78PRKAA10.76053935
79PRKD20.75576559
80FGFR30.74411793
81SGK2230.73719172
82SGK4940.73719172
83IRAK10.73251184
84PLK20.72412194
85YES10.72249982
86SGK30.71968375
87STK40.71548828
88MAPK140.70018885
89TXK0.69032353
90DYRK1B0.68470727
91SMG10.67887323
92GSK3B0.67166000
93RPS6KA60.65465057
94MAPK100.65376434
95RPS6KL10.64087889
96RPS6KC10.64087889
97NEK60.63772346
98PDK10.62283267
99BTK0.61740508
100FGFR20.61704921
101EPHB20.61466110
102MAP3K140.61423804
103STK240.60937800
104PRKCZ0.60026640
105MAP2K30.58836195
106ERN10.58415720
107PDGFRB0.57981451
108STK100.57467194
109MAP2K70.56349209
110BLK0.55972381
111PRKDC0.55652754
112IKBKB0.55436725
113DYRK20.55384304
114MAP3K100.53725353
115MAP3K10.53406487
116AKT10.51935917
117VRK10.50691192
118MAPK80.50425288
119RPS6KA20.50389463
120MARK30.50134896
121FGFR40.49861007
122PRKD30.49832221
123MAPK10.48880014
124GRK70.47555658
125IKBKE0.46569597
126NLK0.46489141
127PIM10.46240688
128MAPK70.46127605
129RPS6KB10.44935921
130RET0.44218528
131KSR10.44169553
132MAPK120.43522615
133DYRK1A0.43117993
134INSRR0.42816878
135PDPK10.42727843
136AURKB0.41846145
137MAP3K50.41684499
138SYK0.40862850
139KIT0.39734075
140MAP2K20.39485268
141TNIK0.39245849
142SGK10.38602949
143PRKAA20.38355867
144MAP3K130.38093418
145CSF1R0.37907140
146CSNK1A1L0.37817406

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.27111938
2Non-homologous end-joining_Homo sapiens_hsa034502.24129411
3Phototransduction_Homo sapiens_hsa047441.92777866
4Cell cycle_Homo sapiens_hsa041101.89598730
5mRNA surveillance pathway_Homo sapiens_hsa030151.71980362
6Basal transcription factors_Homo sapiens_hsa030221.71609150
7Notch signaling pathway_Homo sapiens_hsa043301.60197722
8Homologous recombination_Homo sapiens_hsa034401.57658107
9RNA degradation_Homo sapiens_hsa030181.43085853
10MicroRNAs in cancer_Homo sapiens_hsa052061.33160850
11RNA transport_Homo sapiens_hsa030131.32343373
12Dorso-ventral axis formation_Homo sapiens_hsa043201.29898333
13Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21670007
14Spliceosome_Homo sapiens_hsa030401.21543413
15Base excision repair_Homo sapiens_hsa034101.21074937
16Mismatch repair_Homo sapiens_hsa034301.19037423
17TGF-beta signaling pathway_Homo sapiens_hsa043501.18982683
18VEGF signaling pathway_Homo sapiens_hsa043701.17400717
19RNA polymerase_Homo sapiens_hsa030201.15365894
20Basal cell carcinoma_Homo sapiens_hsa052171.14978637
21NF-kappa B signaling pathway_Homo sapiens_hsa040641.13914198
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.13060715
23Lysine degradation_Homo sapiens_hsa003101.12184060
24Herpes simplex infection_Homo sapiens_hsa051681.09748522
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09454407
26Adherens junction_Homo sapiens_hsa045201.09311739
27Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.09146608
28Prostate cancer_Homo sapiens_hsa052151.08310817
29Colorectal cancer_Homo sapiens_hsa052101.06293073
30Pancreatic cancer_Homo sapiens_hsa052121.05203799
31Thyroid hormone signaling pathway_Homo sapiens_hsa049191.03838665
32Wnt signaling pathway_Homo sapiens_hsa043101.03327235
33Chronic myeloid leukemia_Homo sapiens_hsa052201.01605031
34p53 signaling pathway_Homo sapiens_hsa041151.00692583
35Hedgehog signaling pathway_Homo sapiens_hsa043400.99462341
36Aldosterone synthesis and secretion_Homo sapiens_hsa049250.98969027
37Long-term depression_Homo sapiens_hsa047300.97978736
38Cholinergic synapse_Homo sapiens_hsa047250.96441610
39Estrogen signaling pathway_Homo sapiens_hsa049150.94046170
40HTLV-I infection_Homo sapiens_hsa051660.93059593
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.92691743
42Hippo signaling pathway_Homo sapiens_hsa043900.92113811
43GnRH signaling pathway_Homo sapiens_hsa049120.91789808
44Epstein-Barr virus infection_Homo sapiens_hsa051690.90455730
45Oxytocin signaling pathway_Homo sapiens_hsa049210.89976782
46Small cell lung cancer_Homo sapiens_hsa052220.89702909
47DNA replication_Homo sapiens_hsa030300.89362572
48Axon guidance_Homo sapiens_hsa043600.89335269
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88109242
50Long-term potentiation_Homo sapiens_hsa047200.87423485
51Circadian rhythm_Homo sapiens_hsa047100.86864239
52Measles_Homo sapiens_hsa051620.85029539
53Oocyte meiosis_Homo sapiens_hsa041140.84937024
54Endometrial cancer_Homo sapiens_hsa052130.84207143
55FoxO signaling pathway_Homo sapiens_hsa040680.83700350
56T cell receptor signaling pathway_Homo sapiens_hsa046600.83604768
57Hepatitis B_Homo sapiens_hsa051610.83252725
58Toll-like receptor signaling pathway_Homo sapiens_hsa046200.83124093
59Insulin secretion_Homo sapiens_hsa049110.81421182
60Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81295479
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.80141416
62B cell receptor signaling pathway_Homo sapiens_hsa046620.79965301
63Pathways in cancer_Homo sapiens_hsa052000.79725587
64Platelet activation_Homo sapiens_hsa046110.78938043
65Choline metabolism in cancer_Homo sapiens_hsa052310.78589428
66TNF signaling pathway_Homo sapiens_hsa046680.78166842
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.77318727
68MAPK signaling pathway_Homo sapiens_hsa040100.76100839
69Glutamatergic synapse_Homo sapiens_hsa047240.75996138
70Acute myeloid leukemia_Homo sapiens_hsa052210.75204406
71Morphine addiction_Homo sapiens_hsa050320.74856291
72Circadian entrainment_Homo sapiens_hsa047130.74675104
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74452764
74Calcium signaling pathway_Homo sapiens_hsa040200.73985477
75Nucleotide excision repair_Homo sapiens_hsa034200.73921424
76ABC transporters_Homo sapiens_hsa020100.73904364
77Influenza A_Homo sapiens_hsa051640.73644706
78Insulin resistance_Homo sapiens_hsa049310.73175494
79Osteoclast differentiation_Homo sapiens_hsa043800.72730953
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.72373006
81Insulin signaling pathway_Homo sapiens_hsa049100.71931197
82ErbB signaling pathway_Homo sapiens_hsa040120.71517140
83Primary immunodeficiency_Homo sapiens_hsa053400.70768638
84Vascular smooth muscle contraction_Homo sapiens_hsa042700.70726720
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.70508289
86Tuberculosis_Homo sapiens_hsa051520.70288418
87Taste transduction_Homo sapiens_hsa047420.69513802
88Prolactin signaling pathway_Homo sapiens_hsa049170.69443299
89Non-small cell lung cancer_Homo sapiens_hsa052230.69008213
90Type II diabetes mellitus_Homo sapiens_hsa049300.68608083
91Hepatitis C_Homo sapiens_hsa051600.68408148
92Glioma_Homo sapiens_hsa052140.68145022
93Viral myocarditis_Homo sapiens_hsa054160.68052321
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.68012120
95Melanogenesis_Homo sapiens_hsa049160.67948832
96mTOR signaling pathway_Homo sapiens_hsa041500.67655590
97Viral carcinogenesis_Homo sapiens_hsa052030.67346921
98Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.66890685
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.66383556
100Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.66148011
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66123685
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.65655990
103Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64652342
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64394276
105Toxoplasmosis_Homo sapiens_hsa051450.64014527
106Renal cell carcinoma_Homo sapiens_hsa052110.63692862
107Melanoma_Homo sapiens_hsa052180.63469405
108AMPK signaling pathway_Homo sapiens_hsa041520.63304341
109Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.62755506
110Chemokine signaling pathway_Homo sapiens_hsa040620.62113764
111Nicotine addiction_Homo sapiens_hsa050330.60909356
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60001380
113Inositol phosphate metabolism_Homo sapiens_hsa005620.59850708
114Glucagon signaling pathway_Homo sapiens_hsa049220.59698808
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.59697499
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59375410
117Salivary secretion_Homo sapiens_hsa049700.57644508
118Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57512782
119Ovarian steroidogenesis_Homo sapiens_hsa049130.57057710
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56080387
121HIF-1 signaling pathway_Homo sapiens_hsa040660.55859137
122Rap1 signaling pathway_Homo sapiens_hsa040150.54862145
123Leishmaniasis_Homo sapiens_hsa051400.54764812
124Ras signaling pathway_Homo sapiens_hsa040140.54583331
125cAMP signaling pathway_Homo sapiens_hsa040240.53397378
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.53184606
127Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52956076
128Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52933465
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.52280586
130Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.52202096
131Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52198220
132Proteoglycans in cancer_Homo sapiens_hsa052050.52098422
133Apoptosis_Homo sapiens_hsa042100.51957056
134cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51914391
135Intestinal immune network for IgA production_Homo sapiens_hsa046720.50704816
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49169870

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