FAM196B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cell killing (GO:0031342)6.39324602
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.39324602
3positive regulation of gamma-delta T cell activation (GO:0046645)5.81674398
4natural killer cell mediated immunity (GO:0002228)4.79834963
5natural killer cell mediated cytotoxicity (GO:0042267)4.79834963
6detection of molecule of bacterial origin (GO:0032490)4.72499680
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.44268032
8histone H3-K4 trimethylation (GO:0080182)4.22345648
9positive thymic T cell selection (GO:0045059)4.19632018
10B cell homeostasis (GO:0001782)4.18131834
11neutrophil mediated immunity (GO:0002446)4.12209281
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.07069587
13modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.07069587
14positive regulation by organism of defense response of other organism involved in symbiotic interact4.07069587
15modulation by symbiont of host immune response (GO:0052553)4.07069587
16positive regulation by symbiont of host defense response (GO:0052509)4.07069587
17modulation by symbiont of host defense response (GO:0052031)4.07069587
18regulation of gamma-delta T cell activation (GO:0046643)3.98997636
19positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.96374663
20NIK/NF-kappaB signaling (GO:0038061)3.82153626
21regulation of gamma-delta T cell differentiation (GO:0045586)3.81441461
22positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.80967229
23positive regulation of receptor recycling (GO:0001921)3.79981826
24hepatocyte apoptotic process (GO:0097284)3.79033682
25regulation of B cell receptor signaling pathway (GO:0050855)3.78668724
26hypotonic response (GO:0006971)3.74237390
27microglial cell activation (GO:0001774)3.73971436
28positive regulation of B cell differentiation (GO:0045579)3.72436682
29modulation by symbiont of host cellular process (GO:0044068)3.68924410
30germinal center formation (GO:0002467)3.65332732
31B cell receptor signaling pathway (GO:0050853)3.61238283
32protein localization to endosome (GO:0036010)3.57335753
33regulation of interferon-beta biosynthetic process (GO:0045357)3.56872263
34negative regulation of interleukin-1 beta production (GO:0032691)3.55159657
35positive T cell selection (GO:0043368)3.53768322
36cortical actin cytoskeleton organization (GO:0030866)3.42238605
37negative thymic T cell selection (GO:0045060)3.36912639
38negative T cell selection (GO:0043383)3.34284171
39I-kappaB phosphorylation (GO:0007252)3.33896213
40macroautophagy (GO:0016236)3.33161881
41cell adhesion mediated by integrin (GO:0033627)3.32496648
42negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.32363407
43negative regulation of translation, ncRNA-mediated (GO:0040033)3.32363407
44regulation of translation, ncRNA-mediated (GO:0045974)3.32363407
45negative regulation of anoikis (GO:2000811)3.31347649
46G-protein coupled receptor internalization (GO:0002031)3.24898191
47response to muramyl dipeptide (GO:0032495)3.24505681
48regulation of interleukin-12 biosynthetic process (GO:0045075)3.22586421
49regulation of germinal center formation (GO:0002634)3.20226264
50modulation by virus of host process (GO:0019054)3.18162124
51myeloid leukocyte mediated immunity (GO:0002444)3.16326952
52regulation of integrin activation (GO:0033623)3.13482589
53membrane raft organization (GO:0031579)3.13255063
54neutrophil activation involved in immune response (GO:0002283)3.11240114
55macrophage activation (GO:0042116)3.07956305
56regulation of B cell differentiation (GO:0045577)3.06014518
57cortical cytoskeleton organization (GO:0030865)3.05656251
58negative regulation of DNA repair (GO:0045738)3.05469795
59macrophage activation involved in immune response (GO:0002281)3.04872140
60cellular response to ethanol (GO:0071361)3.03109489
61blood vessel maturation (GO:0001955)3.02730437
62substrate-dependent cell migration (GO:0006929)3.02565519
63positive regulation of fibroblast migration (GO:0010763)3.00155086
64B cell proliferation (GO:0042100)3.00124092
65regulation of necroptotic process (GO:0060544)2.99222042
66positive regulation of cellular amide metabolic process (GO:0034250)2.98966467
67cellular extravasation (GO:0045123)2.98496364
68tolerance induction (GO:0002507)2.98036363
69negative regulation of granulocyte differentiation (GO:0030853)2.96183005
70regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.92761468
71sprouting angiogenesis (GO:0002040)2.91922231
72peptidyl-lysine trimethylation (GO:0018023)2.89498204
73dosage compensation (GO:0007549)2.87467462
74negative regulation of osteoblast proliferation (GO:0033689)2.86858706
75endodermal cell differentiation (GO:0035987)2.85052596
76developmental pigmentation (GO:0048066)2.85029802
77T cell mediated immunity (GO:0002456)2.84393430
78mature B cell differentiation (GO:0002335)2.84186892
79thymic T cell selection (GO:0045061)2.84052002
80T cell selection (GO:0045058)2.83888337
81leukocyte mediated cytotoxicity (GO:0001909)2.83574194
82mitotic sister chromatid cohesion (GO:0007064)2.83033301
83phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.82772365
84negative regulation of interleukin-1 production (GO:0032692)2.82647743
85early endosome to late endosome transport (GO:0045022)2.82052914
86negative regulation of fibroblast apoptotic process (GO:2000270)2.81369507
87pericardium development (GO:0060039)2.80587915
88regulation of macrophage cytokine production (GO:0010935)2.80327679
89response to host immune response (GO:0052572)2.80207473
90response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.80207473
91negative regulation of B cell proliferation (GO:0030889)2.78556044
92negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.78282851
93wound healing, spreading of epidermal cells (GO:0035313)2.77896828
94defense response to protozoan (GO:0042832)2.77709237
95regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.77604812
96nuclear pore complex assembly (GO:0051292)2.77026238
97myeloid cell activation involved in immune response (GO:0002275)2.75085916
98histone H3-K36 demethylation (GO:0070544)2.75005480
99lymphocyte homeostasis (GO:0002260)2.73498083
100histone H3-K4 methylation (GO:0051568)2.73448128
101histone-serine phosphorylation (GO:0035404)2.73302890
102positive regulation of macrophage cytokine production (GO:0060907)2.73037212
103neutrophil activation (GO:0042119)2.72285236
104cytoplasmic mRNA processing body assembly (GO:0033962)2.69032126
105detection of external biotic stimulus (GO:0098581)2.68686354
106synaptic vesicle endocytosis (GO:0048488)2.66441064
107heterotypic cell-cell adhesion (GO:0034113)2.65792783
108positive regulation of interleukin-1 beta secretion (GO:0050718)2.65444873
109response to host (GO:0075136)2.64869082
110response to host defenses (GO:0052200)2.64869082
111response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.64869082
112positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.63314100
113regulation of DNA endoreduplication (GO:0032875)2.63093458
114retrograde transport, vesicle recycling within Golgi (GO:0000301)2.59954961
115neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.58711428
116regulation of anoikis (GO:2000209)2.57722677
117vesicle transport along microtubule (GO:0047496)2.57249216
118positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.55586232
119skin morphogenesis (GO:0043589)2.55558131
120positive regulation of blood vessel endothelial cell migration (GO:0043536)2.55182296
121granulocyte activation (GO:0036230)2.54443439
122phospholipid translocation (GO:0045332)2.54023167
123lipid translocation (GO:0034204)2.54023167
124cell-substrate junction assembly (GO:0007044)2.52666234
125mesodermal cell differentiation (GO:0048333)2.52274867
126regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.50992510
127protein targeting to vacuole (GO:0006623)2.50287486
128protein targeting to lysosome (GO:0006622)2.50287486
129establishment of protein localization to vacuole (GO:0072666)2.50287486
130response to magnesium ion (GO:0032026)2.48738689
131positive regulation of insulin receptor signaling pathway (GO:0046628)2.48531138
132histone mRNA catabolic process (GO:0071044)2.47261651
133phospholipid homeostasis (GO:0055091)2.46993067
134negative regulation of interleukin-12 production (GO:0032695)2.46892959
135regulation of B cell proliferation (GO:0030888)2.46280539
136negative regulation of interleukin-17 production (GO:0032700)2.45743610
137import into cell (GO:0098657)2.44915791
138positive regulation of interferon-alpha production (GO:0032727)2.44344236
139negative regulation of monooxygenase activity (GO:0032769)2.44298985
140cytokine secretion (GO:0050663)2.43146159
141regulation of platelet aggregation (GO:0090330)2.42862045
142clathrin coat assembly (GO:0048268)2.42787591
143cerebellar Purkinje cell differentiation (GO:0021702)2.41974111
144regulation of alpha-beta T cell proliferation (GO:0046640)2.41384687
145positive regulation of interleukin-1 secretion (GO:0050716)2.41350958
146monoubiquitinated protein deubiquitination (GO:0035520)2.41335155
147wound healing, spreading of cells (GO:0044319)2.41045637
148regulation of ARF GTPase activity (GO:0032312)2.40564515
149stress fiber assembly (GO:0043149)2.40431277
150negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.38935551
151regulation of protein polyubiquitination (GO:1902914)2.38766150
152regulation of interferon-alpha production (GO:0032647)2.38244671
153positive regulation of granulocyte differentiation (GO:0030854)2.36613258
154positive regulation of Rac GTPase activity (GO:0032855)2.35861046
155NLS-bearing protein import into nucleus (GO:0006607)2.35213969
156peptidyl-serine phosphorylation (GO:0018105)2.34353120
157positive regulation of B cell proliferation (GO:0030890)2.34232853
158pathway-restricted SMAD protein phosphorylation (GO:0060389)2.34178056
159regulation of interleukin-1 beta secretion (GO:0050706)2.33745514
160lymphocyte proliferation (GO:0046651)2.33084263
161protein K48-linked deubiquitination (GO:0071108)2.32953892
162histone lysine methylation (GO:0034968)2.32936147
163T cell homeostasis (GO:0043029)2.32843823
164positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.32596611
165regulation of beta-amyloid formation (GO:1902003)2.32339234
166activated T cell proliferation (GO:0050798)2.32269270
167embryonic process involved in female pregnancy (GO:0060136)2.31908981
168peptidyl-threonine phosphorylation (GO:0018107)2.28887683
169extracellular fibril organization (GO:0043206)2.28810656

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.45387753
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.28693256
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.79595379
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.35311799
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.34607580
6Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.15742746
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.09475322
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.92616566
9E2F7_22180533_ChIP-Seq_HELA_Human2.86848201
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.85460736
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.84046099
12STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.76502695
13VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.53289318
14BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.49350166
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.47269295
16SCL_19346495_ChIP-Seq_HPC-7_Human2.44087456
17* BRD4_25478319_ChIP-Seq_HGPS_Human2.38163677
18FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.31873857
19SPI1_23127762_ChIP-Seq_K562_Human2.30282218
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.29022791
21RUNX_20019798_ChIP-Seq_JUKART_Human2.28368985
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.25577717
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.24821163
24IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.12627278
25SMAD_19615063_ChIP-ChIP_OVARY_Human2.11860745
26IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.04690240
27CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.91354538
28VDR_21846776_ChIP-Seq_THP-1_Human1.82621998
29ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.81914803
30VDR_24763502_ChIP-Seq_THP-1_Human1.77066375
31PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.75628590
32WT1_19549856_ChIP-ChIP_CCG9911_Human1.72458302
33CJUN_26792858_Chip-Seq_BT549_Human1.67250659
34MYB_26560356_Chip-Seq_TH2_Human1.66863627
35GATA1_22025678_ChIP-Seq_K562_Human1.63858848
36SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.61892613
37SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.61892613
38* VDR_24787735_ChIP-Seq_THP-1_Human1.61518203
39PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.56498854
40PU_27001747_Chip-Seq_BMDM_Mouse1.56127258
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55858705
42MYB_26560356_Chip-Seq_TH1_Human1.54237950
43RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52912399
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.51997533
45E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.51124052
46NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.48094882
47TCF7_22412390_ChIP-Seq_EML_Mouse1.45655018
48CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.44311310
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.44115893
50MAF_26560356_Chip-Seq_TH1_Human1.43345536
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.42733850
52JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.41595672
53SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.41460426
54KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.39649756
55CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.39437549
56JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.38772365
57SPI1_23547873_ChIP-Seq_NB4_Human1.35451136
58SALL4_18804426_ChIP-ChIP_XEN_Mouse1.35449571
59NRF2_20460467_ChIP-Seq_MEFs_Mouse1.34008579
60NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.34008579
61SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30892321
62TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.28755565
63RUNX1_22412390_ChIP-Seq_EML_Mouse1.27300307
64STAT4_19710469_ChIP-ChIP_TH1__Mouse1.26962089
65RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.25001550
66TP53_16413492_ChIP-PET_HCT116_Human1.24160658
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.23972443
68EP300_21415370_ChIP-Seq_HL-1_Mouse1.22632685
69GATA1_19941826_ChIP-Seq_K562_Human1.20667375
70RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.20291982
71UTX_26944678_Chip-Seq_JUKART_Human1.19546928
72GATA3_27048872_Chip-Seq_THYMUS_Human1.19081439
73PPAR_26484153_Chip-Seq_NCI-H1993_Human1.17398902
74* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17253398
75KDM2B_26808549_Chip-Seq_DND41_Human1.17056641
76KDM2B_26808549_Chip-Seq_SUP-B15_Human1.16266882
77SOX9_24532713_ChIP-Seq_HFSC_Mouse1.14136085
78GATA2_19941826_ChIP-Seq_K562_Human1.13733286
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12796596
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12796596
81GBX2_23144817_ChIP-Seq_PC3_Human1.12713307
82MYC_22102868_ChIP-Seq_BL_Human1.12308803
83* TP63_23658742_ChIP-Seq_EP156T_Human1.12122561
84DROSHA_22980978_ChIP-Seq_HELA_Human1.11585427
85GATA2_21666600_ChIP-Seq_HMVEC_Human1.11049439
86OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10778653
87EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09921109
88SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.09284664
89GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07900092
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07512217
91KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05049265
92PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.03542497
93E2F4_17652178_ChIP-ChIP_JURKAT_Human1.03522669
94GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02347472
95TP53_18474530_ChIP-ChIP_U2OS_Human1.01796179
96AHR_22903824_ChIP-Seq_MCF-7_Human1.01485837
97IGF1R_20145208_ChIP-Seq_DFB_Human1.00982760
98EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00964121
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.00004393
100GATA1_19941827_ChIP-Seq_MEL_Mouse0.99948873
101PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98108634
102FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.97233690
103RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96082928
104ARNT_22903824_ChIP-Seq_MCF-7_Human0.96073374
105MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.96037788
106CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94847033
107CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93769862
108ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92303578
109GATA3_26560356_Chip-Seq_TH2_Human0.91800690
110TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91436004
111SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.91364599
112ELK3_25401928_ChIP-Seq_HUVEC_Human0.90916699
113STAT3_23295773_ChIP-Seq_U87_Human0.90862220
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.90719135
115PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87750659
116KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.86438527
117GATA1_19941827_ChIP-Seq_MEL86_Mouse0.86424727
118UBF1/2_26484160_Chip-Seq_HMECs_Human0.85684871
119FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85610888
120TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84652232
121PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.84512909
122STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.84481173
123* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.84360767
124NFIB_24661679_ChIP-Seq_LUNG_Mouse0.84230522
125SMRT_27268052_Chip-Seq_Bcells_Human0.83816966
126EZH2_27294783_Chip-Seq_NPCs_Mouse0.83764992
127FOXO3_23340844_ChIP-Seq_DLD1_Human0.83762391
128TCF4_23295773_ChIP-Seq_U87_Human0.83503107
129EWS_26573619_Chip-Seq_HEK293_Human0.82889953
130PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82279070
131ELK4_26923725_Chip-Seq_MESODERM_Mouse0.82226965
132GATA2_22383799_ChIP-Seq_G1ME_Mouse0.82081758
133NANOG_18555785_Chip-Seq_ESCs_Mouse0.81614904
134RARB_27405468_Chip-Seq_BRAIN_Mouse0.81282944
135E2F1_18555785_Chip-Seq_ESCs_Mouse0.81116469
136AR_21572438_ChIP-Seq_LNCaP_Human0.79681426
137TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.76757371
138CMYC_18555785_Chip-Seq_ESCs_Mouse0.76485590
139KDM2B_26808549_Chip-Seq_JURKAT_Human0.75691616

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.99567933
2MP0005174_abnormal_tail_pigmentation3.85293568
3MP0000015_abnormal_ear_pigmentation3.42974264
4MP0003705_abnormal_hypodermis_morpholog3.20725658
5MP0003172_abnormal_lysosome_physiology3.15834914
6MP0009278_abnormal_bone_marrow2.89539030
7MP0002166_altered_tumor_susceptibility2.70192510
8MP0001835_abnormal_antigen_presentation2.60248552
9MP0003183_abnormal_peptide_metabolism2.46830277
10MP0003279_aneurysm2.45516727
11MP0002396_abnormal_hematopoietic_system2.41203228
12MP0003828_pulmonary_edema2.30839303
13MP0005058_abnormal_lysosome_morphology2.29867581
14MP0010368_abnormal_lymphatic_system2.28829040
15MP0001800_abnormal_humoral_immune2.27895609
16MP0003950_abnormal_plasma_membrane2.22850400
17MP0004510_myositis2.21779535
18MP0006054_spinal_hemorrhage2.14541235
19MP0002006_tumorigenesis2.11501141
20MP0002877_abnormal_melanocyte_morpholog2.07302018
21MP0000569_abnormal_digit_pigmentation10.0962815
22MP0005623_abnormal_meninges_morphology1.97233467
23MP0004883_abnormal_blood_vessel1.96962093
24MP0002452_abnormal_antigen_presenting1.92942062
25MP0003787_abnormal_imprinting1.88189645
26MP0004272_abnormal_basement_membrane1.88008013
27MP0003724_increased_susceptibility_to1.87908558
28MP0000371_diluted_coat_color1.87377181
29MP0000685_abnormal_immune_system1.86575431
30MP0003300_gastrointestinal_ulcer1.86409550
31MP0005451_abnormal_body_composition1.84178975
32MP0001790_abnormal_immune_system1.83222747
33MP0005387_immune_system_phenotype1.83222747
34MP0002332_abnormal_exercise_endurance1.83021644
35MP0002723_abnormal_immune_serum1.79856004
36MP0002419_abnormal_innate_immunity1.78860606
37MP0005671_abnormal_response_to1.77798565
38MP0001879_abnormal_lymphatic_vessel1.76892134
39MP0005464_abnormal_platelet_physiology1.74793522
40MP0000767_abnormal_smooth_muscle1.69092714
41MP0001819_abnormal_immune_cell1.67537685
42MP0002420_abnormal_adaptive_immunity1.67494436
43MP0005164_abnormal_response_to1.66633793
44MP0001545_abnormal_hematopoietic_system1.62757839
45MP0005397_hematopoietic_system_phenotyp1.62757839
46MP0005000_abnormal_immune_tolerance1.62411959
47MP0003303_peritoneal_inflammation1.60838915
48MP0003191_abnormal_cellular_cholesterol1.60479404
49MP0005275_abnormal_skin_tensile1.60187879
50MP0002398_abnormal_bone_marrow1.57263535
51MP0005023_abnormal_wound_healing1.54330930
52MP0005075_abnormal_melanosome_morpholog1.49687919
53MP0001873_stomach_inflammation1.48953053
54MP0004947_skin_inflammation1.44899422
55MP0002009_preneoplasia1.44328139
56MP0008057_abnormal_DNA_replication1.41339711
57MP0003221_abnormal_cardiomyocyte_apopto1.39786667
58MP0003763_abnormal_thymus_physiology1.38839875
59MP0005076_abnormal_cell_differentiation1.38689496
60MP0005025_abnormal_response_to1.37568817
61MP0000689_abnormal_spleen_morphology1.37283446
62MP0003436_decreased_susceptibility_to1.36366962
63MP0000703_abnormal_thymus_morphology1.34441403
64MP0000716_abnormal_immune_system1.34210638
65MP0005257_abnormal_intraocular_pressure1.33666479
66MP0009046_muscle_twitch1.28466023
67MP0001915_intracranial_hemorrhage1.27567371
68MP0004808_abnormal_hematopoietic_stem1.27167669
69MP0005503_abnormal_tendon_morphology1.24596354
70MP0002405_respiratory_system_inflammati1.23826904
71MP0002095_abnormal_skin_pigmentation1.20845832
72MP0002722_abnormal_immune_system1.20353394
73MP0005595_abnormal_vascular_smooth1.20240360
74MP0010307_abnormal_tumor_latency1.19221651
75MP0001958_emphysema1.15291346
76MP0004859_abnormal_synaptic_plasticity1.12262433
77MP0003329_amyloid_beta_deposits1.05247707
78MP0002060_abnormal_skin_morphology1.05220929
79MP0004484_altered_response_of1.04640159
80MP0001853_heart_inflammation1.03137524
81MP0002429_abnormal_blood_cell1.02334477
82MP0000249_abnormal_blood_vessel1.00796617
83MP0003448_altered_tumor_morphology1.00662969
84MP0004381_abnormal_hair_follicle0.99851972
85MP0003091_abnormal_cell_migration0.97993359
86MP0000013_abnormal_adipose_tissue0.97901154
87MP0002075_abnormal_coat/hair_pigmentati0.97230249
88MP0005409_darkened_coat_color0.94176715
89MP0000733_abnormal_muscle_development0.91814091
90MP0006082_CNS_inflammation0.91641664
91MP0002133_abnormal_respiratory_system0.91167035
92MP0005388_respiratory_system_phenotype0.91167035
93MP0002928_abnormal_bile_duct0.89834564
94MP0000604_amyloidosis0.88927566
95MP0008877_abnormal_DNA_methylation0.86088062
96MP0000428_abnormal_craniofacial_morphol0.85112184
97MP0010155_abnormal_intestine_physiology0.83909696
98MP0003690_abnormal_glial_cell0.83796391
99MP0001851_eye_inflammation0.83302263
100MP0010094_abnormal_chromosome_stability0.83213740
101MP0004084_abnormal_cardiac_muscle0.82017503
102MP0008961_abnormal_basal_metabolism0.81505556
103MP0001845_abnormal_inflammatory_respons0.81415717
104MP0001533_abnormal_skeleton_physiology0.81012130
105MP0002148_abnormal_hypersensitivity_rea0.80706968
106MP0003045_fibrosis0.80116556
107MP0002295_abnormal_pulmonary_circulatio0.80013333
108MP0001348_abnormal_lacrimal_gland0.79976556
109MP0002168_other_aberrant_phenotype0.78332388
110MP0004233_abnormal_muscle_weight0.76948016
111MP0003866_abnormal_defecation0.73304956
112MP0005621_abnormal_cell_physiology0.72399936
113MP0002128_abnormal_blood_circulation0.71596248
114MP0009785_altered_susceptibility_to0.70584312
115MP0002896_abnormal_bone_mineralization0.69843515
116MP0001243_abnormal_dermal_layer0.68870063
117MP0002998_abnormal_bone_remodeling0.68753500
118MP0008260_abnormal_autophagy0.68256020
119MP0008569_lethality_at_weaning0.68068792
120MP0002925_abnormal_cardiovascular_devel0.67301285
121MP0005165_increased_susceptibility_to0.67252581
122MP0001542_abnormal_bone_strength0.67123581
123MP0001186_pigmentation_phenotype0.66953049
124MP0005423_abnormal_somatic_nervous0.66544653
125MP0004811_abnormal_neuron_physiology0.65775379
126MP0009745_abnormal_behavioral_response0.61723231
127MP0002067_abnormal_sensory_capabilities0.61704489
128MP0003635_abnormal_synaptic_transmissio0.61124151
129MP0002064_seizures0.59097172
130MP0000858_altered_metastatic_potential0.56984806
131MP0010352_gastrointestinal_tract_polyps0.56613406
132MP0005310_abnormal_salivary_gland0.56552273
133MP0003656_abnormal_erythrocyte_physiolo0.54107707
134MP0002933_joint_inflammation0.53176513
135MP0003566_abnormal_cell_adhesion0.53076423
136MP0008058_abnormal_DNA_repair0.52941041
137MP0004742_abnormal_vestibular_system0.52745509
138MP0005384_cellular_phenotype0.52708547
139MP0003634_abnormal_glial_cell0.51819734
140MP0002063_abnormal_learning/memory/cond0.50662665
141MP0005386_behavior/neurological_phenoty0.50278404
142MP0004924_abnormal_behavior0.50278404
143MP0002572_abnormal_emotion/affect_behav0.49515089
144MP0002254_reproductive_system_inflammat0.47117939
145MP0000465_gastrointestinal_hemorrhage0.46427995
146MP0000778_abnormal_nervous_system0.45530842

Predicted human phenotypes

RankGene SetZ-score
1Recurrent bacterial skin infections (HP:0005406)5.06790073
2Recurrent abscess formation (HP:0002722)4.89844594
3Protrusio acetabuli (HP:0003179)4.52011014
4Premature rupture of membranes (HP:0001788)4.01988161
5Arterial tortuosity (HP:0005116)3.95755820
6Vascular tortuosity (HP:0004948)3.91130236
7Abnormality of the fingertips (HP:0001211)3.79607899
8Peritonitis (HP:0002586)3.77830754
9Aortic aneurysm (HP:0004942)3.75183350
10Aortic dissection (HP:0002647)3.62083922
11Stomatitis (HP:0010280)3.54156558
12Recurrent fungal infections (HP:0002841)3.49984434
13Absent frontal sinuses (HP:0002688)3.46680511
14Periodontitis (HP:0000704)3.42386126
15Osteolytic defects of the hand bones (HP:0009699)3.22590690
16Osteolytic defects of the phalanges of the hand (HP:0009771)3.22590690
17Spondylolisthesis (HP:0003302)3.20767981
18Recurrent skin infections (HP:0001581)3.18429284
19Elevated erythrocyte sedimentation rate (HP:0003565)3.18355106
20Gingivitis (HP:0000230)3.09962564
21Prostate neoplasm (HP:0100787)3.09347075
22Recurrent viral infections (HP:0004429)3.08539115
23Conjunctival telangiectasia (HP:0000524)3.06948598
24Mediastinal lymphadenopathy (HP:0100721)3.06329105
25Large earlobe (HP:0009748)2.98557140
26Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.96284428
27Thyroiditis (HP:0100646)2.92105036
28Eczematoid dermatitis (HP:0000976)2.91720970
29Thoracolumbar scoliosis (HP:0002944)2.87705909
30Recurrent cutaneous fungal infections (HP:0011370)2.86491345
31Chronic mucocutaneous candidiasis (HP:0002728)2.86491345
32Volvulus (HP:0002580)2.84965152
33Spontaneous hematomas (HP:0007420)2.77920608
34Subacute progressive viral hepatitis (HP:0006572)2.77394834
35Macroorchidism (HP:0000053)2.74452242
36Abnormality of the vasculature of the conjunctiva (HP:0008054)2.73848373
37Ankle contracture (HP:0006466)2.73843784
38Optic neuritis (HP:0100653)2.72195171
39Retrobulbar optic neuritis (HP:0100654)2.72195171
40Wormian bones (HP:0002645)2.70802041
41Overgrowth (HP:0001548)2.70666514
42Generalized hypopigmentation (HP:0007513)2.64107986
43Colitis (HP:0002583)2.62346887
44Glucose intolerance (HP:0000833)2.62256332
45Febrile seizures (HP:0002373)2.61940657
46Mitral valve prolapse (HP:0001634)2.61804077
47Dilatation of the ascending aorta (HP:0005111)2.61723593
48Frequent falls (HP:0002359)2.60039296
49Heterotopia (HP:0002282)2.54809357
50Submucous cleft hard palate (HP:0000176)2.49885717
51T lymphocytopenia (HP:0005403)2.42777480
52Atrophic scars (HP:0001075)2.41700587
53Leukocytosis (HP:0001974)2.40331766
54Genu recurvatum (HP:0002816)2.40025731
55Narrow palate (HP:0000189)2.38415362
56Premature loss of primary teeth (HP:0006323)2.36124539
57Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.35458246
58Vasculitis (HP:0002633)2.34234476
59Myositis (HP:0100614)2.33969531
60Abnormality of the frontal sinuses (HP:0002687)2.33905691
61Slow saccadic eye movements (HP:0000514)2.30846260
62Hematochezia (HP:0002573)2.30260545
63Cervical subluxation (HP:0003308)2.29970022
64Ocular albinism (HP:0001107)2.26453257
65Eosinophilia (HP:0001880)2.26104706
66Drooling (HP:0002307)2.25912889
67Excessive salivation (HP:0003781)2.25912889
68Cerebral inclusion bodies (HP:0100314)2.25578812
69Follicular hyperkeratosis (HP:0007502)2.25423784
70Abnormality of T cell number (HP:0011839)2.25213292
71Progressive hearing impairment (HP:0001730)2.24892251
72Increased mean platelet volume (HP:0011877)2.21861876
73Distal lower limb amyotrophy (HP:0008944)2.21760845
74Orchitis (HP:0100796)2.21015824
75Spinal rigidity (HP:0003306)2.19739000
76Dislocated radial head (HP:0003083)2.19131831
77Myocardial infarction (HP:0001658)2.18520699
78Urethral obstruction (HP:0000796)2.17230434
79Lower limb amyotrophy (HP:0007210)2.16313998
80Disinhibition (HP:0000734)2.14265122
81Widely spaced teeth (HP:0000687)2.13934809
82Urinary bladder sphincter dysfunction (HP:0002839)2.13823767
83Recurrent gram-negative bacterial infections (HP:0005420)2.13187344
84Lip pit (HP:0100267)2.13123392
85Chromsome breakage (HP:0040012)2.10868024
86Joint laxity (HP:0001388)2.10654162
87Neurodegeneration (HP:0002180)2.10489104
88Progressive sensorineural hearing impairment (HP:0000408)2.10478629
89Thick nail (HP:0001805)2.10437400
90Hypoplasia of the thymus (HP:0000778)2.08917613
91Iris hypopigmentation (HP:0007730)2.08209558
92Increased variability in muscle fiber diameter (HP:0003557)2.07299712
93Delayed closure of the anterior fontanelle (HP:0001476)2.07154012
94Autoimmune thrombocytopenia (HP:0001973)2.06957994
95Inappropriate behavior (HP:0000719)2.06641652
96Genetic anticipation (HP:0003743)2.06284789
97Broad face (HP:0000283)2.05872432
98Aortic regurgitation (HP:0001659)2.05293763
99Abnormal platelet volume (HP:0011876)2.04908889
100Chromosomal breakage induced by crosslinking agents (HP:0003221)2.04275682
101Osteomyelitis (HP:0002754)2.04111844
102Soft skin (HP:0000977)2.03888250
103Gingival bleeding (HP:0000225)2.01539325
104Panhypogammaglobulinemia (HP:0003139)2.01487348
105Inflammation of the large intestine (HP:0002037)2.01016756
106Abnormality of the columella (HP:0009929)1.98790696
107Viral hepatitis (HP:0006562)1.98737220
108Long toe (HP:0010511)1.98337779
109Broad ribs (HP:0000885)1.98101784
110Abnormal hair whorl (HP:0010721)1.97839913
111Pustule (HP:0200039)1.97782329
112Mitral stenosis (HP:0001718)1.97598610
113Abnormality of skeletal muscle fiber size (HP:0012084)1.97398676
114Aneurysm (HP:0002617)1.96666520
115Abnormality of the radial head (HP:0003995)1.96513175
116Mitral regurgitation (HP:0001653)1.95763799
117Agammaglobulinemia (HP:0004432)1.95109883
118Prominent nose (HP:0000448)1.94049567
119Increased connective tissue (HP:0009025)1.93436642
120Supranuclear gaze palsy (HP:0000605)1.93056542
121Abnormality of the prostate (HP:0008775)1.92950660
122Pelvic girdle muscle weakness (HP:0003749)1.92884254
123Orthostatic hypotension (HP:0001278)1.92433343
124IgA deficiency (HP:0002720)1.91426426
125Postural instability (HP:0002172)1.90214193
126Abnormal glucose tolerance (HP:0001952)1.88705472
127Short nail (HP:0001799)1.87543203
128Acute myeloid leukemia (HP:0004808)1.87488556
129Long eyelashes (HP:0000527)1.87128598
130Truncal obesity (HP:0001956)1.87088987
131Vertebral arch anomaly (HP:0008438)1.86547250
132Epistaxis (HP:0000421)1.86487326
133Abnormality of macrophages (HP:0004311)1.85331751
134Papillary thyroid carcinoma (HP:0002895)1.84195126
135Syringomyelia (HP:0003396)1.84155794
136Spinal cord lesions (HP:0100561)1.84155794
137Vertebral compression fractures (HP:0002953)1.84141506
138Increased cerebral lipofuscin (HP:0011813)1.84034962
139Protruding tongue (HP:0010808)1.83210395
140Abnormality of the peritoneum (HP:0002585)1.83107638
141Abnormality of eosinophils (HP:0001879)1.82823224
142Urinary urgency (HP:0000012)1.82630315
143Leukopenia (HP:0001882)1.81661832
144Cellulitis (HP:0100658)1.80583322
145Gastrointestinal inflammation (HP:0004386)1.80185241
146Pulmonary infiltrates (HP:0002113)1.79231655
147Abnormality of the musculature of the pelvis (HP:0001469)1.77146919
148Abnormality of the hip-girdle musculature (HP:0001445)1.77146919
149Meningitis (HP:0001287)1.76995686
150Abnormality of oral frenula (HP:0000190)1.76318465
151Blue sclerae (HP:0000592)1.75174461
152Bladder diverticulum (HP:0000015)1.74977607
153Type 1 muscle fiber predominance (HP:0003803)1.74795356
154Abnormality of B cell number (HP:0010975)1.73829930
155B lymphocytopenia (HP:0010976)1.73829930
156Gastrointestinal infarctions (HP:0005244)1.73768300
157Restrictive lung disease (HP:0002091)1.73589372
158Cerebral aneurysm (HP:0004944)1.73366963
159Shallow orbits (HP:0000586)1.72190767
160Fatigue (HP:0012378)1.72145501
161Impaired smooth pursuit (HP:0007772)1.72068880
162Gaze-evoked nystagmus (HP:0000640)1.71982668
163Aqueductal stenosis (HP:0002410)1.71740025
164Arterial thrombosis (HP:0004420)1.71495488
165Menorrhagia (HP:0000132)1.71279185
166Polycythemia (HP:0001901)1.69854680
167Decreased skull ossification (HP:0004331)1.69583513
168Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.69550858
169Papilledema (HP:0001085)1.69226317
170Mucosal telangiectasiae (HP:0100579)1.68963652
171Scanning speech (HP:0002168)1.68901021
172Resting tremor (HP:0002322)1.67753043

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.57593700
2MAP3K133.27725724
3SIK23.20355462
4CDK122.79782531
5CAMK1G2.75772294
6MAP3K142.68223078
7PTK2B2.66354487
8MAP2K32.65154189
9BLK2.59470898
10TAOK32.42720845
11CAMK1D2.42404638
12MAP4K12.40272050
13TXK2.36598329
14PIK3CG2.36369812
15TYK22.13624992
16PDGFRA2.11800595
17KIT2.09255202
18BMPR21.92053863
19JAK11.87800480
20BRD41.79210771
21IKBKE1.74904711
22TIE11.71296193
23MOS1.66892784
24HCK1.59009543
25JAK31.56176474
26FES1.54633702
27GRK51.47074609
28YES11.45742302
29ITK1.44789497
30AKT31.43836510
31CDK61.43625573
32SYK1.36473419
33IKBKB1.32620578
34IRAK41.32138355
35DAPK21.31187066
36TTN1.27883745
37SGK21.26019739
38FGR1.25496915
39PTK21.25345190
40CSK1.18647345
41SGK31.18630286
42LCK1.15405605
43MAP3K91.14823575
44WNK11.13129446
45CSF1R1.12090593
46EPHB11.09880267
47KSR11.09716814
48ICK1.08730496
49TBK11.07823939
50ROCK21.05864614
51CHUK1.04308815
52SGK11.03475738
53MAP3K101.03394071
54HIPK21.02836645
55ZAP701.01803185
56FGFR31.00559240
57KSR20.99588795
58SCYL20.98296377
59MYLK0.95180475
60MELK0.94812078
61IRAK30.93894329
62RAF10.89469594
63MAP3K30.89067252
64LRRK20.88425071
65MAPK100.87463328
66TRPM70.86970490
67NTRK30.85797862
68PDGFRB0.85588101
69FLT30.85586124
70MAP3K50.84797657
71NTRK10.82723023
72TEC0.82025571
73DAPK10.81117350
74ADRBK10.81018545
75CAMKK20.79600108
76EGFR0.79482018
77PAK60.78493549
78MAP3K40.78278836
79PNCK0.78248476
80MAP3K60.75653052
81RIPK10.75650633
82IRAK20.75344290
83ATR0.75145109
84LATS10.74216034
85MAP3K10.72792551
86JAK20.72329933
87LYN0.71292292
88IRAK10.70225136
89PAK20.69815074
90TGFBR20.69341518
91CDK90.67233714
92RET0.66883696
93UHMK10.66736073
94MAPK70.66112606
95PRKD20.65996611
96SGK2230.64140718
97SGK4940.64140718
98CDK80.64023199
99PIM10.63440471
100TRIB30.63110409
101ERBB20.62543572
102FRK0.62499218
103CAMKK10.61587889
104NEK20.60476240
105CDC70.60368322
106PKN10.60011981
107MTOR0.59884829
108GRK70.59382847
109MAPK120.57863272
110CDC42BPA0.56906840
111PDK10.56640051
112DYRK1A0.56100663
113DDR20.56016331
114PRKCQ0.55352001
115STK100.54696373
116ATM0.52450752
117MATK0.51899741
118PAK30.51353682
119STK380.51231059
120STK40.50773856
121GRK60.50638640
122BTK0.50510341
123MARK30.50148055
124CAMK40.49640943
125MARK20.49621081
126MAP3K70.49187730
127FYN0.48533328
128MAP2K40.47325367
129CDK50.46557016
130NTRK20.45369642
131PLK20.45306555
132NEK90.44569666
133PRKAA20.44550569
134DMPK0.44079622
135MINK10.43589248
136ERBB30.43188555
137ERBB40.43043895
138MARK10.42810518
139MAPK80.42748658
140PKN20.42448415
141CLK10.41758221
142STK110.41742553
143MAP3K20.41133904
144PRKCH0.41085242

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.43628094
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.27800750
3Osteoclast differentiation_Homo sapiens_hsa043802.08250617
4NF-kappa B signaling pathway_Homo sapiens_hsa040641.95850700
5NOD-like receptor signaling pathway_Homo sapiens_hsa046211.88193339
6Type II diabetes mellitus_Homo sapiens_hsa049301.84824796
7T cell receptor signaling pathway_Homo sapiens_hsa046601.83755341
8Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.82539193
9Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.80338450
10Focal adhesion_Homo sapiens_hsa045101.71746923
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.69926876
12Primary immunodeficiency_Homo sapiens_hsa053401.69630278
13Phosphatidylinositol signaling system_Homo sapiens_hsa040701.62222612
14Leishmaniasis_Homo sapiens_hsa051401.59511007
15Measles_Homo sapiens_hsa051621.57928040
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49291204
17Chronic myeloid leukemia_Homo sapiens_hsa052201.49051269
18Dorso-ventral axis formation_Homo sapiens_hsa043201.48821786
19Proteoglycans in cancer_Homo sapiens_hsa052051.45231980
20ECM-receptor interaction_Homo sapiens_hsa045121.43052699
21Intestinal immune network for IgA production_Homo sapiens_hsa046721.39979751
22Non-homologous end-joining_Homo sapiens_hsa034501.34276463
23Chemokine signaling pathway_Homo sapiens_hsa040621.32825311
24Influenza A_Homo sapiens_hsa051641.31698175
25Tuberculosis_Homo sapiens_hsa051521.31252232
26mTOR signaling pathway_Homo sapiens_hsa041501.28891942
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.28880932
28TNF signaling pathway_Homo sapiens_hsa046681.27859424
29Pancreatic cancer_Homo sapiens_hsa052121.23416579
30Inositol phosphate metabolism_Homo sapiens_hsa005621.20860681
31Lysine degradation_Homo sapiens_hsa003101.19780585
32Adherens junction_Homo sapiens_hsa045201.18581701
33Neurotrophin signaling pathway_Homo sapiens_hsa047221.17627449
34GnRH signaling pathway_Homo sapiens_hsa049121.17439444
35Hepatitis B_Homo sapiens_hsa051611.14480130
36Amoebiasis_Homo sapiens_hsa051461.13129527
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.12594035
38Toxoplasmosis_Homo sapiens_hsa051451.08789935
39Prostate cancer_Homo sapiens_hsa052151.07751685
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.07111739
41Caffeine metabolism_Homo sapiens_hsa002321.06661484
42Hematopoietic cell lineage_Homo sapiens_hsa046401.06222093
43Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.04507781
44Apoptosis_Homo sapiens_hsa042101.03427656
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.03300486
46Acute myeloid leukemia_Homo sapiens_hsa052211.00778612
47Prolactin signaling pathway_Homo sapiens_hsa049170.96495012
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96241428
49Olfactory transduction_Homo sapiens_hsa047400.95489006
50Non-small cell lung cancer_Homo sapiens_hsa052230.95367027
51Allograft rejection_Homo sapiens_hsa053300.95345232
52Carbohydrate digestion and absorption_Homo sapiens_hsa049730.94138702
53Colorectal cancer_Homo sapiens_hsa052100.93599893
54Thyroid cancer_Homo sapiens_hsa052160.92969307
55Synaptic vesicle cycle_Homo sapiens_hsa047210.92522072
56Glioma_Homo sapiens_hsa052140.92351995
57Bladder cancer_Homo sapiens_hsa052190.91925953
58Hepatitis C_Homo sapiens_hsa051600.91576452
59Thyroid hormone signaling pathway_Homo sapiens_hsa049190.91302418
60Autoimmune thyroid disease_Homo sapiens_hsa053200.90945177
61MicroRNAs in cancer_Homo sapiens_hsa052060.89712658
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.89425537
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89074933
64Rap1 signaling pathway_Homo sapiens_hsa040150.88330185
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.87738752
66Pathways in cancer_Homo sapiens_hsa052000.86682050
67VEGF signaling pathway_Homo sapiens_hsa043700.86519032
68ErbB signaling pathway_Homo sapiens_hsa040120.86252702
69PI3K-Akt signaling pathway_Homo sapiens_hsa041510.86065308
70Platelet activation_Homo sapiens_hsa046110.85602707
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.85463169
72Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84300372
73Pertussis_Homo sapiens_hsa051330.84106679
74FoxO signaling pathway_Homo sapiens_hsa040680.83732774
75HIF-1 signaling pathway_Homo sapiens_hsa040660.83180972
76Melanoma_Homo sapiens_hsa052180.81921055
77Choline metabolism in cancer_Homo sapiens_hsa052310.81460210
78Shigellosis_Homo sapiens_hsa051310.81375409
79Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.80431861
80MAPK signaling pathway_Homo sapiens_hsa040100.79583211
81Graft-versus-host disease_Homo sapiens_hsa053320.79221111
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.78989291
83Small cell lung cancer_Homo sapiens_hsa052220.78425541
84Herpes simplex infection_Homo sapiens_hsa051680.77983840
85Notch signaling pathway_Homo sapiens_hsa043300.77968979
86Cholinergic synapse_Homo sapiens_hsa047250.77757871
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.77306007
88Gap junction_Homo sapiens_hsa045400.76796686
89Viral myocarditis_Homo sapiens_hsa054160.76305699
90Ras signaling pathway_Homo sapiens_hsa040140.75922226
91Morphine addiction_Homo sapiens_hsa050320.73385624
92Long-term potentiation_Homo sapiens_hsa047200.73062937
93Oxytocin signaling pathway_Homo sapiens_hsa049210.72559567
94p53 signaling pathway_Homo sapiens_hsa041150.72501306
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.72471550
96Insulin signaling pathway_Homo sapiens_hsa049100.72457667
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.72400501
98Salmonella infection_Homo sapiens_hsa051320.71545292
99Rheumatoid arthritis_Homo sapiens_hsa053230.70664999
100African trypanosomiasis_Homo sapiens_hsa051430.70407017
101Phagosome_Homo sapiens_hsa041450.69582301
102Insulin resistance_Homo sapiens_hsa049310.68118598
103Viral carcinogenesis_Homo sapiens_hsa052030.67869920
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67761943
105Legionellosis_Homo sapiens_hsa051340.67564122
106Collecting duct acid secretion_Homo sapiens_hsa049660.67232803
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66142144
108HTLV-I infection_Homo sapiens_hsa051660.65739264
109Estrogen signaling pathway_Homo sapiens_hsa049150.65572533
110Epstein-Barr virus infection_Homo sapiens_hsa051690.64885092
111Aldosterone synthesis and secretion_Homo sapiens_hsa049250.64592111
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63573660
113Nicotine addiction_Homo sapiens_hsa050330.63235340
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.63048256
115Endocytosis_Homo sapiens_hsa041440.62369495
116Renin secretion_Homo sapiens_hsa049240.61757894
117Malaria_Homo sapiens_hsa051440.61541916
118Renal cell carcinoma_Homo sapiens_hsa052110.58602195
119Asthma_Homo sapiens_hsa053100.58221829
120TGF-beta signaling pathway_Homo sapiens_hsa043500.57007591
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.57004429
122Endometrial cancer_Homo sapiens_hsa052130.56917436
123Axon guidance_Homo sapiens_hsa043600.56859528
124Leukocyte transendothelial migration_Homo sapiens_hsa046700.54879596
125Long-term depression_Homo sapiens_hsa047300.54775361
126Gastric acid secretion_Homo sapiens_hsa049710.52374591
127Dilated cardiomyopathy_Homo sapiens_hsa054140.52016025
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50494972
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49283424
130Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.49236817

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »