FAM204A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cytosolic calcium ion concentration (GO:0051481)5.10216469
2behavioral response to ethanol (GO:0048149)4.37451942
3protein complex biogenesis (GO:0070271)3.83982928
4negative regulation of cAMP-mediated signaling (GO:0043951)3.83938532
5behavioral response to nicotine (GO:0035095)3.75875987
6adult feeding behavior (GO:0008343)3.74603390
7water-soluble vitamin biosynthetic process (GO:0042364)3.70971420
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.68222022
9ether lipid metabolic process (GO:0046485)3.66662861
10DNA ligation (GO:0006266)3.60423778
11mitochondrial respiratory chain complex assembly (GO:0033108)3.59480283
12mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.55510479
13epithelial cilium movement (GO:0003351)3.54499660
14maturation of 5.8S rRNA (GO:0000460)3.51218197
15mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49477536
16mitochondrial respiratory chain complex I assembly (GO:0032981)3.49477536
17NADH dehydrogenase complex assembly (GO:0010257)3.49477536
18mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.42094076
19piRNA metabolic process (GO:0034587)3.37797251
20replication fork processing (GO:0031297)3.36214951
21transcription elongation from RNA polymerase III promoter (GO:0006385)3.31509105
22termination of RNA polymerase III transcription (GO:0006386)3.31509105
23neural tube formation (GO:0001841)3.31082600
24ATP synthesis coupled proton transport (GO:0015986)3.27512458
25energy coupled proton transport, down electrochemical gradient (GO:0015985)3.27512458
26platelet dense granule organization (GO:0060155)3.26032304
27RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.18379376
28proteasome assembly (GO:0043248)3.18342487
29negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.17129334
30detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.13035450
31opioid receptor signaling pathway (GO:0038003)3.12311235
32regulation of double-strand break repair via homologous recombination (GO:0010569)3.08772180
33response to pheromone (GO:0019236)3.08245555
34respiratory chain complex IV assembly (GO:0008535)3.07247697
35kinetochore organization (GO:0051383)3.07016867
36cellular ketone body metabolic process (GO:0046950)3.05680943
37mitotic sister chromatid cohesion (GO:0007064)3.04209439
387-methylguanosine mRNA capping (GO:0006370)3.02916867
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.02063313
40dopamine transport (GO:0015872)3.01801723
41regulation of cilium movement (GO:0003352)2.99599982
42RNA capping (GO:0036260)2.98364593
437-methylguanosine RNA capping (GO:0009452)2.98364593
44axoneme assembly (GO:0035082)2.96030413
45central nervous system myelination (GO:0022010)2.95268380
46axon ensheathment in central nervous system (GO:0032291)2.95268380
47indolalkylamine metabolic process (GO:0006586)2.94712713
48adaptation of signaling pathway (GO:0023058)2.94234865
49negative regulation of DNA-dependent DNA replication (GO:2000104)2.93530001
50nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.92788079
51cytochrome complex assembly (GO:0017004)2.91389747
52CENP-A containing nucleosome assembly (GO:0034080)2.85102127
53DNA double-strand break processing (GO:0000729)2.84174472
54exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.83518753
55indole-containing compound catabolic process (GO:0042436)2.81528907
56indolalkylamine catabolic process (GO:0046218)2.81528907
57tryptophan catabolic process (GO:0006569)2.81528907
58kinetochore assembly (GO:0051382)2.80008311
59electron transport chain (GO:0022900)2.79965241
60respiratory electron transport chain (GO:0022904)2.79375030
61protein neddylation (GO:0045116)2.79056812
62transcription elongation from RNA polymerase II promoter (GO:0006368)2.78363125
63chromatin remodeling at centromere (GO:0031055)2.77743090
64ketone body metabolic process (GO:1902224)2.77309132
65detection of light stimulus involved in sensory perception (GO:0050962)2.75199978
66detection of light stimulus involved in visual perception (GO:0050908)2.75199978
67positive regulation of cAMP-mediated signaling (GO:0043950)2.75155918
68resolution of meiotic recombination intermediates (GO:0000712)2.73078996
69regulation of acrosome reaction (GO:0060046)2.72940895
70GTP biosynthetic process (GO:0006183)2.72907017
71regulation of DNA endoreduplication (GO:0032875)2.71929791
72mannosylation (GO:0097502)2.71797038
73regulation of protein glycosylation (GO:0060049)2.71492187
74regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.71322854
75establishment of integrated proviral latency (GO:0075713)2.71036471
76neuronal action potential (GO:0019228)2.71017749
77protein prenylation (GO:0018342)2.70823263
78prenylation (GO:0097354)2.70823263
79recombinational repair (GO:0000725)2.70556233
80ncRNA catabolic process (GO:0034661)2.69537235
81intra-S DNA damage checkpoint (GO:0031573)2.68626847
82double-strand break repair via homologous recombination (GO:0000724)2.68248875
83GPI anchor metabolic process (GO:0006505)2.67465698
84cilium movement (GO:0003341)2.66989247
85attachment of spindle microtubules to kinetochore (GO:0008608)2.66418916
86protein-cofactor linkage (GO:0018065)2.65689320
87anterograde synaptic vesicle transport (GO:0048490)2.65645072
88nonmotile primary cilium assembly (GO:0035058)2.64889995
89tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.62957704
90RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.62957704
91DNA methylation involved in gamete generation (GO:0043046)2.62634013
92photoreceptor cell maintenance (GO:0045494)2.61641149
93transcription-coupled nucleotide-excision repair (GO:0006283)2.61139796
94negative regulation of execution phase of apoptosis (GO:1900118)2.60318716
95positive regulation of oligodendrocyte differentiation (GO:0048714)2.60245635
96ribonucleoprotein complex disassembly (GO:0032988)2.60239061
97histone mRNA metabolic process (GO:0008334)2.58998558
98protein localization to cilium (GO:0061512)2.58362930
99cilium organization (GO:0044782)2.58222333
100DNA-templated transcription, elongation (GO:0006354)2.57197538
101glycerol ether metabolic process (GO:0006662)2.56615221
102maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.55349705
103sulfation (GO:0051923)2.55296325
104cilium assembly (GO:0042384)2.53281151
105protein K11-linked deubiquitination (GO:0035871)2.53031167
106intraciliary transport (GO:0042073)2.51785656
107cornea development in camera-type eye (GO:0061303)2.51475132
108DNA damage response, detection of DNA damage (GO:0042769)2.49602039
109regulation of hexokinase activity (GO:1903299)2.49388716
110regulation of glucokinase activity (GO:0033131)2.49388716
111adenosine metabolic process (GO:0046085)2.48896458
112establishment of viral latency (GO:0019043)2.47512016
113ether metabolic process (GO:0018904)2.47300013
114viral mRNA export from host cell nucleus (GO:0046784)2.46465402
115centriole replication (GO:0007099)2.45341258
116C-terminal protein lipidation (GO:0006501)2.44671500
117transmission of nerve impulse (GO:0019226)2.43493910
118retinal cone cell development (GO:0046549)2.43356499
119C-terminal protein amino acid modification (GO:0018410)2.43258630
120organelle disassembly (GO:1903008)2.43050125
121positive regulation of viral transcription (GO:0050434)2.42413763
122tryptophan metabolic process (GO:0006568)2.41462640
123guanosine-containing compound biosynthetic process (GO:1901070)2.40864651
124DNA replication-independent nucleosome assembly (GO:0006336)2.40746199
125DNA replication-independent nucleosome organization (GO:0034724)2.40746199
126L-fucose catabolic process (GO:0042355)2.40683384
127fucose catabolic process (GO:0019317)2.40683384
128L-fucose metabolic process (GO:0042354)2.40683384
129kynurenine metabolic process (GO:0070189)2.40414807
130ribosomal small subunit biogenesis (GO:0042274)2.38921193
131protein K11-linked ubiquitination (GO:0070979)2.36501864
132signal peptide processing (GO:0006465)2.33690226
133termination of RNA polymerase I transcription (GO:0006363)2.33210168
134histone exchange (GO:0043486)2.31834368
135otic vesicle formation (GO:0030916)2.31186735
136regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.30230115
137negative regulation of myoblast differentiation (GO:0045662)2.29894864
138UTP biosynthetic process (GO:0006228)2.28722732
139transcription elongation from RNA polymerase I promoter (GO:0006362)2.27897161
140CTP biosynthetic process (GO:0006241)2.27323537
141CTP metabolic process (GO:0046036)2.27323537
142viral protein processing (GO:0019082)2.27283236
143peptidyl-histidine modification (GO:0018202)2.27231390
144preassembly of GPI anchor in ER membrane (GO:0016254)2.26022094
145nucleotide-excision repair (GO:0006289)2.23904855
146nucleotide-excision repair, DNA gap filling (GO:0006297)2.23032468
147DNA topological change (GO:0006265)2.22277142
148spermatid nucleus differentiation (GO:0007289)2.21694156
149regulation of mitochondrial translation (GO:0070129)2.21499942
150regulation of meiosis I (GO:0060631)2.19915885
151V(D)J recombination (GO:0033151)2.19875067
152transcription from RNA polymerase I promoter (GO:0006360)2.19521939
153spindle checkpoint (GO:0031577)2.19099702
154cotranslational protein targeting to membrane (GO:0006613)2.18248961
155sister chromatid cohesion (GO:0007062)2.17494133
156negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.17147599
157meiotic chromosome segregation (GO:0045132)2.17096117
158DNA-templated transcription, termination (GO:0006353)2.17089491
159photoreceptor cell differentiation (GO:0046530)2.16810850
160eye photoreceptor cell differentiation (GO:0001754)2.16810850
161protein K63-linked deubiquitination (GO:0070536)2.16722204
162neuron fate determination (GO:0048664)2.16630422
163establishment of chromosome localization (GO:0051303)2.15866335
164deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.15093669
165SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.14552270
166mitotic metaphase plate congression (GO:0007080)2.13252499
167protein targeting to ER (GO:0045047)2.12596044
168limb bud formation (GO:0060174)2.12147016
169positive regulation of meiosis (GO:0045836)2.11655872
170cilium morphogenesis (GO:0060271)2.11371765
171activated T cell proliferation (GO:0050798)2.10856832
172somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.10547601
173somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.10547601
174isotype switching (GO:0045190)2.10547601
175positive regulation of glial cell differentiation (GO:0045687)2.10379910
176DNA deamination (GO:0045006)2.10102524
177metaphase plate congression (GO:0051310)2.09721422
178centriole assembly (GO:0098534)2.08465274
179negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.08127654
180mitotic spindle checkpoint (GO:0071174)2.07664449
181negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.06814041
182lymphoid progenitor cell differentiation (GO:0002320)2.06218805
183cullin deneddylation (GO:0010388)2.04282233
184transcription from RNA polymerase III promoter (GO:0006383)2.04230300
185protein localization to endoplasmic reticulum (GO:0070972)2.04076629
186positive regulation of cell cycle checkpoint (GO:1901978)2.03169710
187positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.03052741
188transcription initiation from RNA polymerase I promoter (GO:0006361)2.02339707
189regulation of female gonad development (GO:2000194)2.02233833

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human3.66310935
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.55977878
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.37275229
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.20702782
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.00500280
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.76835476
7ZNF274_21170338_ChIP-Seq_K562_Hela2.76248957
8GBX2_23144817_ChIP-Seq_PC3_Human2.57811615
9CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.54070845
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42964546
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.37153445
12ELK1_19687146_ChIP-ChIP_HELA_Human2.34755465
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.34488826
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.25674486
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.24115167
16VDR_23849224_ChIP-Seq_CD4+_Human2.22773088
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.21855510
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16718676
19BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.15519248
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.07999784
21POU3F2_20337985_ChIP-ChIP_501MEL_Human1.99700868
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.98914484
23MYC_18555785_ChIP-Seq_MESCs_Mouse1.97148400
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.96033083
25IGF1R_20145208_ChIP-Seq_DFB_Human1.92378766
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92049186
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91940504
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.91284176
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.91079951
30FUS_26573619_Chip-Seq_HEK293_Human1.90458913
31POU5F1_16153702_ChIP-ChIP_HESCs_Human1.89943480
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.89160797
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80326969
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.76439538
35PCGF2_27294783_Chip-Seq_ESCs_Mouse1.74400241
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73401176
37DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.72002354
38ETS1_20019798_ChIP-Seq_JURKAT_Human1.69989582
39CREB1_15753290_ChIP-ChIP_HEK293T_Human1.69772597
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.68979898
41RNF2_27304074_Chip-Seq_NSC_Mouse1.68347387
42AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.67080492
43EZH2_22144423_ChIP-Seq_EOC_Human1.64308228
44FOXP3_21729870_ChIP-Seq_TREG_Human1.63379908
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.63327960
46CBP_20019798_ChIP-Seq_JUKART_Human1.63327960
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63259350
48DCP1A_22483619_ChIP-Seq_HELA_Human1.61554689
49EWS_26573619_Chip-Seq_HEK293_Human1.60857131
50PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59597612
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.59331591
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.58891594
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56921232
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.56658988
55FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.54848868
56EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.54520213
57POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.53411579
58TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.53411579
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.51705320
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49809321
61NANOG_19829295_ChIP-Seq_ESCs_Human1.48154525
62SOX2_19829295_ChIP-Seq_ESCs_Human1.48154525
63SALL1_21062744_ChIP-ChIP_HESCs_Human1.48015683
64TTF2_22483619_ChIP-Seq_HELA_Human1.47269769
65MYC_19030024_ChIP-ChIP_MESCs_Mouse1.47206251
66SMAD4_21799915_ChIP-Seq_A2780_Human1.47017135
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47006357
68MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.46964847
69HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.46546912
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.46003339
71AR_25329375_ChIP-Seq_VCAP_Human1.42839416
72FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.42575853
73PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41099078
74TP53_22573176_ChIP-Seq_HFKS_Human1.40962500
75PIAS1_25552417_ChIP-Seq_VCAP_Human1.40425923
76ER_23166858_ChIP-Seq_MCF-7_Human1.40368961
77STAT3_23295773_ChIP-Seq_U87_Human1.40266865
78BCAT_22108803_ChIP-Seq_LS180_Human1.37896205
79SMAD3_21741376_ChIP-Seq_EPCs_Human1.37060730
80PCGF2_27294783_Chip-Seq_NPCs_Mouse1.35482020
81VDR_22108803_ChIP-Seq_LS180_Human1.35452048
82PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35020425
83BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32457452
84SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31222087
85TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30716868
86CBX2_27304074_Chip-Seq_ESCs_Mouse1.30287544
87E2F1_21310950_ChIP-Seq_MCF-7_Human1.29760246
88HTT_18923047_ChIP-ChIP_STHdh_Human1.28959968
89TCF4_23295773_ChIP-Seq_U87_Human1.28878618
90KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.28519274
91XRN2_22483619_ChIP-Seq_HELA_Human1.27328182
92TAF15_26573619_Chip-Seq_HEK293_Human1.25521831
93TCF4_22108803_ChIP-Seq_LS180_Human1.24234673
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.21415671
95ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21228992
96FLI1_21867929_ChIP-Seq_TH2_Mouse1.20624912
97MYC_18940864_ChIP-ChIP_HL60_Human1.19741394
98WT1_19549856_ChIP-ChIP_CCG9911_Human1.19297273
99MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.18325680
100CRX_20693478_ChIP-Seq_RETINA_Mouse1.18324701
101GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17589665
102CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.17009657
103OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16732505
104IRF1_19129219_ChIP-ChIP_H3396_Human1.16488016
105NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15463739
106KLF5_20875108_ChIP-Seq_MESCs_Mouse1.15134933
107ELK1_22589737_ChIP-Seq_MCF10A_Human1.15067539
108SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13415723
109E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13336957
110FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12252715
111FOXA1_25329375_ChIP-Seq_VCAP_Human1.12252715
112MYC_18358816_ChIP-ChIP_MESCs_Mouse1.12054515
113SUZ12_27294783_Chip-Seq_NPCs_Mouse1.10647207
114SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10575454
115NOTCH1_21737748_ChIP-Seq_TLL_Human1.10439005
116CDX2_22108803_ChIP-Seq_LS180_Human1.09587038
117SRF_21415370_ChIP-Seq_HL-1_Mouse1.09360699
118GABP_19822575_ChIP-Seq_HepG2_Human1.09189256
119FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07796200
120NFE2_27457419_Chip-Seq_LIVER_Mouse1.07650060
121RUNX2_22187159_ChIP-Seq_PCA_Human1.07551832
122RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07397575
123PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.06577484
124YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06051933
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05848272
126REST_19997604_ChIP-ChIP_NEURONS_Mouse1.05399242
127NANOG_18555785_Chip-Seq_ESCs_Mouse1.05007053
128EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04983358
129SMAD4_21741376_ChIP-Seq_EPCs_Human1.04873505
130AR_21909140_ChIP-Seq_LNCAP_Human1.04125772
131STAT3_18555785_Chip-Seq_ESCs_Mouse1.03521288
132MYCN_18555785_ChIP-Seq_MESCs_Mouse1.03008752
133P300_18555785_Chip-Seq_ESCs_Mouse1.02427744
134SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.00459425
135TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99799901
136OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99402632
137EZH2_27294783_Chip-Seq_NPCs_Mouse0.99016978
138ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.96861721
139CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.96044387
140MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93887075
141SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93617680
142P53_22387025_ChIP-Seq_ESCs_Mouse0.93582961
143CMYC_18555785_Chip-Seq_ESCs_Mouse0.93548818
144E2F1_18555785_Chip-Seq_ESCs_Mouse0.92950416
145SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.92303012
146FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91976375
147BP1_19119308_ChIP-ChIP_Hs578T_Human0.91942598
148MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91890718
149NMYC_18555785_Chip-Seq_ESCs_Mouse0.90078971
150P300_19829295_ChIP-Seq_ESCs_Human0.89725055

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.40067522
2MP0008057_abnormal_DNA_replication3.29554113
3MP0006292_abnormal_olfactory_placode2.93226172
4MP0008877_abnormal_DNA_methylation2.76896636
5MP0001188_hyperpigmentation2.71761667
6MP0001968_abnormal_touch/_nociception2.62301199
7MP0002638_abnormal_pupillary_reflex2.47894311
8MP0008058_abnormal_DNA_repair2.44637587
9MP0005551_abnormal_eye_electrophysiolog2.41543581
10MP0002876_abnormal_thyroid_physiology2.29801458
11MP0001529_abnormal_vocalization2.24749280
12MP0002837_dystrophic_cardiac_calcinosis2.23466029
13MP0009379_abnormal_foot_pigmentation2.14622035
14MP0010094_abnormal_chromosome_stability2.10929510
15MP0002938_white_spotting2.10070304
16MP0003693_abnormal_embryo_hatching2.07103542
17MP0003136_yellow_coat_color1.98771122
18MP0002102_abnormal_ear_morphology1.98656056
19MP0008789_abnormal_olfactory_epithelium1.96949908
20MP0003195_calcinosis1.94431623
21MP0009046_muscle_twitch1.93059291
22MP0002877_abnormal_melanocyte_morpholog1.87081282
23MP0005645_abnormal_hypothalamus_physiol1.85220494
24MP0005084_abnormal_gallbladder_morpholo1.85207709
25MP0006072_abnormal_retinal_apoptosis1.82227671
26MP0001346_abnormal_lacrimal_gland1.81860056
27MP0008007_abnormal_cellular_replicative1.80721049
28MP0003077_abnormal_cell_cycle1.80503050
29MP0004957_abnormal_blastocyst_morpholog1.78070673
30MP0009780_abnormal_chondrocyte_physiolo1.76921523
31MP0002163_abnormal_gland_morphology1.74426717
32MP0000015_abnormal_ear_pigmentation1.73837559
33MP0003646_muscle_fatigue1.71213117
34MP0005171_absent_coat_pigmentation1.64530151
35MP0002009_preneoplasia1.64186984
36MP0003718_maternal_effect1.62675743
37MP0000427_abnormal_hair_cycle1.61786245
38MP0008932_abnormal_embryonic_tissue1.59652964
39MP0009745_abnormal_behavioral_response1.57722471
40MP0002272_abnormal_nervous_system1.56875387
41MP0003763_abnormal_thymus_physiology1.55350804
42MP0002928_abnormal_bile_duct1.54109597
43MP0004142_abnormal_muscle_tone1.54050581
44MP0000631_abnormal_neuroendocrine_gland1.51720942
45MP0005408_hypopigmentation1.49513946
46MP0001485_abnormal_pinna_reflex1.49290010
47MP0003786_premature_aging1.47296282
48MP0001486_abnormal_startle_reflex1.45453804
49MP0004134_abnormal_chest_morphology1.45245609
50MP0001986_abnormal_taste_sensitivity1.44738173
51MP0001905_abnormal_dopamine_level1.42772378
52MP0005379_endocrine/exocrine_gland_phen1.42492782
53MP0001501_abnormal_sleep_pattern1.41715714
54MP0002736_abnormal_nociception_after1.41678307
55MP0000566_synostosis1.41078179
56MP0002751_abnormal_autonomic_nervous1.38760596
57MP0003787_abnormal_imprinting1.38750602
58MP0003880_abnormal_central_pattern1.38512603
59MP0008872_abnormal_physiological_respon1.36625850
60MP0001984_abnormal_olfaction1.36214350
61MP0009697_abnormal_copulation1.33882997
62MP0002177_abnormal_outer_ear1.33212631
63MP0002210_abnormal_sex_determination1.32364847
64MP0003121_genomic_imprinting1.31353054
65MP0002160_abnormal_reproductive_system1.30531031
66MP0009250_abnormal_appendicular_skeleto1.30209444
67MP0006035_abnormal_mitochondrial_morpho1.30024069
68MP0003937_abnormal_limbs/digits/tail_de1.28617394
69MP0005646_abnormal_pituitary_gland1.25031349
70MP0005499_abnormal_olfactory_system1.24308956
71MP0005394_taste/olfaction_phenotype1.24308956
72MP0000049_abnormal_middle_ear1.23207397
73MP0005075_abnormal_melanosome_morpholog1.22641709
74MP0005389_reproductive_system_phenotype1.22356672
75MP0004742_abnormal_vestibular_system1.22018590
76MP0003111_abnormal_nucleus_morphology1.21343428
77MP0004215_abnormal_myocardial_fiber1.17503202
78MP0002733_abnormal_thermal_nociception1.15661454
79MP0005195_abnormal_posterior_eye1.13925204
80MP0005671_abnormal_response_to1.12432366
81MP0006036_abnormal_mitochondrial_physio1.12107332
82MP0005367_renal/urinary_system_phenotyp1.11767658
83MP0000516_abnormal_urinary_system1.11767658
84MP0004381_abnormal_hair_follicle1.11709954
85MP0002653_abnormal_ependyma_morphology1.11356397
86MP0000778_abnormal_nervous_system1.09671715
87MP0001929_abnormal_gametogenesis1.08672092
88MP0001286_abnormal_eye_development1.07923235
89MP0006276_abnormal_autonomic_nervous1.07332482
90MP0005409_darkened_coat_color1.07260243
91MP0003011_delayed_dark_adaptation1.06980561
92MP0002234_abnormal_pharynx_morphology1.06271308
93MP0003806_abnormal_nucleotide_metabolis1.05865531
94MP0002557_abnormal_social/conspecific_i1.05065115
95MP0001970_abnormal_pain_threshold1.04105857
96MP0001324_abnormal_eye_pigmentation1.03303440
97MP0002572_abnormal_emotion/affect_behav1.01958205
98MP0005174_abnormal_tail_pigmentation0.99712285
99MP0002095_abnormal_skin_pigmentation0.99549518
100MP0000613_abnormal_salivary_gland0.99448340
101MP0003315_abnormal_perineum_morphology0.99311085
102MP0002067_abnormal_sensory_capabilities0.98535043
103MP0001145_abnormal_male_reproductive0.96544859
104MP0001919_abnormal_reproductive_system0.95771322
105MP0004145_abnormal_muscle_electrophysio0.95531898
106MP0000372_irregular_coat_pigmentation0.95469112
107MP0000026_abnormal_inner_ear0.95396263
108MP0000653_abnormal_sex_gland0.95061091
109MP0010386_abnormal_urinary_bladder0.94853729
110MP0003567_abnormal_fetal_cardiomyocyte0.94333804
111MP0003890_abnormal_embryonic-extraembry0.93517603
112MP0009764_decreased_sensitivity_to0.93480809
113MP0003950_abnormal_plasma_membrane0.93129775
114MP0010030_abnormal_orbit_morphology0.93005027
115MP0001293_anophthalmia0.92840041
116MP0003755_abnormal_palate_morphology0.90657279
117MP0003943_abnormal_hepatobiliary_system0.90399284
118MP0002735_abnormal_chemical_nociception0.90213353
119MP0005248_abnormal_Harderian_gland0.90194861
120MP0002396_abnormal_hematopoietic_system0.90035764
121MP0004885_abnormal_endolymph0.87542741
122MP0004924_abnormal_behavior0.86630199
123MP0005386_behavior/neurological_phenoty0.86630199
124MP0000762_abnormal_tongue_morphology0.85682879
125MP0005257_abnormal_intraocular_pressure0.84709875
126MP0002116_abnormal_craniofacial_bone0.84707766
127MP0008995_early_reproductive_senescence0.83738185
128MP0005391_vision/eye_phenotype0.83489813
129MP0002064_seizures0.81744597
130MP0003633_abnormal_nervous_system0.80830332
131MP0000350_abnormal_cell_proliferation0.80479760
132MP0008775_abnormal_heart_ventricle0.80241160
133MP0000383_abnormal_hair_follicle0.79262581
134MP0001764_abnormal_homeostasis0.77321582
135MP0003861_abnormal_nervous_system0.76483270
136MP0001186_pigmentation_phenotype0.75765013
137MP0001119_abnormal_female_reproductive0.75181654
138MP0001963_abnormal_hearing_physiology0.73515931
139MP0002752_abnormal_somatic_nervous0.72854412
140MP0002282_abnormal_trachea_morphology0.71861965
141MP0002277_abnormal_respiratory_mucosa0.71186052
142MP0000013_abnormal_adipose_tissue0.71033666
143MP0005253_abnormal_eye_physiology0.70981081
144MP0001730_embryonic_growth_arrest0.70619288
145MP0009333_abnormal_splenocyte_physiolog0.68513791
146MP0004147_increased_porphyrin_level0.68391270
147MP0000313_abnormal_cell_death0.65060919
148MP0003698_abnormal_male_reproductive0.64959454
149MP0000920_abnormal_myelination0.64857461
150MP0003123_paternal_imprinting0.64136433
151MP0002114_abnormal_axial_skeleton0.62645182
152MP0003938_abnormal_ear_development0.62052409
153MP0002019_abnormal_tumor_incidence0.61742433
154MP0000703_abnormal_thymus_morphology0.61662902
155MP0002085_abnormal_embryonic_tissue0.60372047

Predicted human phenotypes

RankGene SetZ-score
1Thyroid-stimulating hormone excess (HP:0002925)3.78352294
2Intestinal atresia (HP:0011100)3.40433057
3Medial flaring of the eyebrow (HP:0010747)3.03044371
4Congenital stationary night blindness (HP:0007642)2.95802582
5Increased CSF lactate (HP:0002490)2.93605961
6Adrenal hypoplasia (HP:0000835)2.86455422
7Gait imbalance (HP:0002141)2.84162814
8True hermaphroditism (HP:0010459)2.83108301
9Abnormality of the renal medulla (HP:0100957)2.82324821
10Abnormality of the renal cortex (HP:0011035)2.81088386
11Large for gestational age (HP:0001520)2.78525697
12Congenital primary aphakia (HP:0007707)2.76859355
13Methylmalonic acidemia (HP:0002912)2.70980291
14Volvulus (HP:0002580)2.70271027
15Acute encephalopathy (HP:0006846)2.68662410
16Lipid accumulation in hepatocytes (HP:0006561)2.61556023
17Molar tooth sign on MRI (HP:0002419)2.60851846
18Abnormality of midbrain morphology (HP:0002418)2.60851846
19Chronic hepatic failure (HP:0100626)2.58448547
20Nephrogenic diabetes insipidus (HP:0009806)2.56754857
21Abolished electroretinogram (ERG) (HP:0000550)2.56300585
22Hyperventilation (HP:0002883)2.52808291
23Pancreatic fibrosis (HP:0100732)2.50881219
24Gaze-evoked nystagmus (HP:0000640)2.49177847
25Focal motor seizures (HP:0011153)2.48843790
26Pancreatic cysts (HP:0001737)2.47528424
27Abnormal rod and cone electroretinograms (HP:0008323)2.47353191
28Methylmalonic aciduria (HP:0012120)2.46743508
29Optic nerve hypoplasia (HP:0000609)2.44833311
30Renal cortical cysts (HP:0000803)2.44079649
31Renal Fanconi syndrome (HP:0001994)2.38441148
32Tubular atrophy (HP:0000092)2.38031609
33Vaginal atresia (HP:0000148)2.36874684
34Hypoplasia of the fovea (HP:0007750)2.32921042
35Aplasia/Hypoplasia of the fovea (HP:0008060)2.32921042
36Severe combined immunodeficiency (HP:0004430)2.31741099
37Small epiphyses (HP:0010585)2.31164628
38Genital tract atresia (HP:0001827)2.31114637
39Congenital, generalized hypertrichosis (HP:0004540)2.30396876
40Abnormality of the ileum (HP:0001549)2.28691194
41Type II lissencephaly (HP:0007260)2.25980513
42Hepatocellular necrosis (HP:0001404)2.25262712
43Polydipsia (HP:0001959)2.24221200
44Abnormal drinking behavior (HP:0030082)2.24221200
45Attenuation of retinal blood vessels (HP:0007843)2.22137804
46Pendular nystagmus (HP:0012043)2.22097597
47Abnormality of the fovea (HP:0000493)2.20659367
48Cystic liver disease (HP:0006706)2.19693661
49Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.18560176
50Pancreatic islet-cell hyperplasia (HP:0004510)2.17994506
51Abnormality of macular pigmentation (HP:0008002)2.17500135
52Median cleft lip (HP:0000161)2.14104136
53Absent rod-and cone-mediated responses on ERG (HP:0007688)2.13210045
54Hepatic necrosis (HP:0002605)2.13002123
55Abnormal hair whorl (HP:0010721)2.12508157
56Male pseudohermaphroditism (HP:0000037)2.10785536
57Acute necrotizing encephalopathy (HP:0006965)2.09981680
58Oligodactyly (hands) (HP:0001180)2.08113825
59Reticulocytopenia (HP:0001896)2.07681918
60Abnormality of incisor morphology (HP:0011063)2.07509739
61Gastrointestinal atresia (HP:0002589)2.07339044
62Optic nerve coloboma (HP:0000588)2.06462567
63Retinal dysplasia (HP:0007973)2.06342569
64Facial hemangioma (HP:0000329)2.05886750
65Irregular epiphyses (HP:0010582)2.05438948
66Preaxial hand polydactyly (HP:0001177)2.05435000
67Agitation (HP:0000713)2.04934524
683-Methylglutaconic aciduria (HP:0003535)2.04860230
69Sclerocornea (HP:0000647)2.02558579
70Aplasia/Hypoplasia of the lens (HP:0008063)2.02318926
71Febrile seizures (HP:0002373)2.01999174
72Broad-based gait (HP:0002136)1.98098622
73Abnormal biliary tract physiology (HP:0012439)1.97853103
74Bile duct proliferation (HP:0001408)1.97853103
75Ectopic kidney (HP:0000086)1.95616270
76Abnormality of the columella (HP:0009929)1.95450440
77Furrowed tongue (HP:0000221)1.95424960
78Aplasia/Hypoplasia of the uvula (HP:0010293)1.95132288
79Aplasia/Hypoplasia of the tibia (HP:0005772)1.95116922
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.94936288
81Abnormality of alanine metabolism (HP:0010916)1.94936288
82Hyperalaninemia (HP:0003348)1.94936288
83Lissencephaly (HP:0001339)1.93189933
84Aplasia/Hypoplasia of the tongue (HP:0010295)1.93047557
85Optic disc pallor (HP:0000543)1.92140618
86Anencephaly (HP:0002323)1.91595774
87Carpal bone hypoplasia (HP:0001498)1.91518697
88Sex reversal (HP:0012245)1.90883020
89Abnormal sex determination (HP:0012244)1.90883020
90Increased serum lactate (HP:0002151)1.90078777
91Decreased central vision (HP:0007663)1.89937706
92Type 2 muscle fiber atrophy (HP:0003554)1.88957672
93Cupped ear (HP:0000378)1.88324904
9411 pairs of ribs (HP:0000878)1.87493812
95Bifid tongue (HP:0010297)1.87414391
96Abnormality of the labia minora (HP:0012880)1.85447104
97Exertional dyspnea (HP:0002875)1.84656853
98Congenital hepatic fibrosis (HP:0002612)1.84121338
99Abnormality of renal resorption (HP:0011038)1.83525838
100Fair hair (HP:0002286)1.82561484
101Patellar aplasia (HP:0006443)1.82119698
102Cerebral edema (HP:0002181)1.81441388
103Patchy hypopigmentation of hair (HP:0011365)1.81426443
104White forelock (HP:0002211)1.81368275
105Muscle fiber atrophy (HP:0100295)1.79530162
106Hypothermia (HP:0002045)1.79120953
107Chorioretinal atrophy (HP:0000533)1.78500243
108Chromsome breakage (HP:0040012)1.78492414
109Type I transferrin isoform profile (HP:0003642)1.77635345
110Abnormal respiratory motile cilium morphology (HP:0005938)1.77058504
111Abnormal respiratory epithelium morphology (HP:0012253)1.77058504
112Poor coordination (HP:0002370)1.76127996
113Barrel-shaped chest (HP:0001552)1.75658986
114Aplasia/hypoplasia of the uterus (HP:0008684)1.74646319
115Nephronophthisis (HP:0000090)1.74306445
116Cerebellar dysplasia (HP:0007033)1.74288248
117Polyuria (HP:0000103)1.74168919
118Congenital sensorineural hearing impairment (HP:0008527)1.74001114
119Abnormality of chromosome stability (HP:0003220)1.73595325
120Abnormal pancreas size (HP:0012094)1.71282881
121Flat capital femoral epiphysis (HP:0003370)1.71129760
122Aplasia/Hypoplasia of the patella (HP:0006498)1.71100194
123Dialeptic seizures (HP:0011146)1.70467432
124Increased corneal curvature (HP:0100692)1.70286397
125Keratoconus (HP:0000563)1.70286397
126Submucous cleft hard palate (HP:0000176)1.68281076
127Alacrima (HP:0000522)1.67779237
128Aganglionic megacolon (HP:0002251)1.67678892
129Capillary hemangiomas (HP:0005306)1.67648386
130Increased intramyocellular lipid droplets (HP:0012240)1.67374644
131Abnormality of the pons (HP:0007361)1.67318515
132IgG deficiency (HP:0004315)1.67306806
133Progressive macrocephaly (HP:0004481)1.67096058
134Decreased lacrimation (HP:0000633)1.66987622
135Focal seizures (HP:0007359)1.66601861
136Renal hypoplasia (HP:0000089)1.65547582
137Combined immunodeficiency (HP:0005387)1.62784642
138Thyroiditis (HP:0100646)1.62687301
139Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.62562929
140Broad foot (HP:0001769)1.62383533
141Mitochondrial inheritance (HP:0001427)1.61784104
142Hypoplastic iliac wings (HP:0002866)1.61594995
143Postaxial foot polydactyly (HP:0001830)1.60942923
144Abnormality of the septum pellucidum (HP:0007375)1.60061354
145Absent septum pellucidum (HP:0001331)1.58957630
146Increased hepatocellular lipid droplets (HP:0006565)1.58578533
147Abnormality of the phalanges of the 5th finger (HP:0004213)1.58182306
148Colon cancer (HP:0003003)1.57948890
149Prominent nasal bridge (HP:0000426)1.56908665
150Multicystic kidney dysplasia (HP:0000003)1.56864425
151Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.56762044
152Abnormal lung lobation (HP:0002101)1.56740795
153Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.56625229
154Microglossia (HP:0000171)1.55212950
155Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.54805185
156Nasolacrimal duct obstruction (HP:0000579)1.54607604
157Abnormal mitochondria in muscle tissue (HP:0008316)1.54503605
158Aplasia/Hypoplasia of the sternum (HP:0006714)1.54143122
159Abnormality of abdominal situs (HP:0011620)1.53841871
160Abdominal situs inversus (HP:0003363)1.53841871
161Entropion (HP:0000621)1.53529704
162Epiphyseal dysplasia (HP:0002656)1.53110816
163Postaxial hand polydactyly (HP:0001162)1.52829699
164Abnormality of DNA repair (HP:0003254)1.52695294
165Nephroblastoma (Wilms tumor) (HP:0002667)1.52401287
166Chromosomal breakage induced by crosslinking agents (HP:0003221)1.51204024
167Atresia of the external auditory canal (HP:0000413)1.50554180
168Embryonal renal neoplasm (HP:0011794)1.50304152
169Facial cleft (HP:0002006)1.49880850
170Glossoptosis (HP:0000162)1.49808954

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ADRBK23.91838404
2VRK12.91084346
3BUB12.77563001
4SRPK12.76934318
5BCR2.68736745
6PBK2.66209718
7MAP4K22.34758747
8CDK82.29618339
9PINK12.27522907
10STK162.19530197
11CDC72.06965785
12NLK2.00011887
13DYRK21.99790095
14PNCK1.96117560
15TXK1.94616337
16PLK21.89734144
17MAP3K41.85758672
18TLK11.80025603
19GRK11.76668807
20MAPK151.72267731
21DYRK31.67053413
22BMPR1B1.66020859
23MKNK11.64925665
24PASK1.60949965
25MST41.60265479
26TNIK1.59458938
27BRSK21.56207529
28TESK21.53326732
29CSNK1G31.53034594
30STK391.50806356
31STK38L1.50784480
32MAPK131.49096955
33ACVR1B1.45057257
34PLK31.44893017
35MKNK21.44707090
36TRIM281.43369336
37CSNK1G11.43198304
38EIF2AK31.42381704
39CLK11.38668893
40LIMK11.38051899
41HIPK21.35999975
42ERBB31.32922034
43YES11.31396885
44MARK31.30647593
45TAOK31.28757084
46PLK41.27506736
47ADRBK11.27080448
48MELK1.24585385
49PRKCE1.20647227
50INSRR1.15909560
51PRKCG1.15399198
52NEK61.10173182
53TGFBR11.09433872
54CHEK21.08760902
55ZAK1.08032147
56CSNK1A1L1.07961559
57UHMK11.07803787
58WNK41.04984997
59MAP3K61.04418440
60MUSK1.03766460
61CDK31.02797950
62CSNK1G21.02576110
63AURKB1.02211025
64MAP3K121.00227465
65CDK90.96862073
66SIK30.96773120
67PAK30.95409091
68RPS6KA50.95304474
69NME10.93560087
70EIF2AK10.93249250
71AURKA0.86602473
72MAP3K20.84747972
73CASK0.84640332
74ATR0.81458518
75NUAK10.81279156
76OXSR10.79514085
77OBSCN0.76845573
78WEE10.76785285
79CCNB10.75855375
80PLK10.75232681
81BMPR20.74648401
82NME20.74407896
83RPS6KA40.72568840
84MAP2K70.70112078
85PIM20.69179376
86EPHA40.68609139
87CAMK2A0.67829744
88VRK20.65534152
89MAP3K30.65325984
90WNK30.64691443
91ATM0.62652290
92IRAK40.61340621
93EIF2AK20.61086822
94TEC0.60867020
95STK30.59037202
96PTK2B0.58743631
97MAP3K140.58236632
98CHEK10.56533148
99CDK190.55911662
100BCKDK0.55543719
101ITK0.55452597
102MAPKAPK50.54749965
103FGFR20.53822800
104CSNK2A10.53210486
105TRPM70.52088574
106IRAK10.51911272
107CDK70.51027817
108PRKCI0.50386662
109STK100.50132899
110BRAF0.48833592
111PHKG20.48332028
112PHKG10.48332028
113TIE10.48103341
114PIM10.47629644
115CDK140.46353746
116PKN10.46187447
117GRK50.45760900
118TAF10.45612367
119BRSK10.45433190
120NEK10.44789221
121PRKG10.43824580
122FLT30.43369439
123PRKD20.42122555
124FRK0.40663048
125CDK10.40268798
126PRKACA0.40057342
127DYRK1A0.39950207
128PRKCQ0.39709763
129CSNK2A20.39544285
130CHUK0.39360230
131MARK10.39182607
132LYN0.38929780
133CSNK1A10.38099686
134CDK20.36760154
135PIK3CG0.36671537
136MOS0.35879083
137CAMK10.35572661
138GRK70.35482637
139CSNK1E0.35231006
140KIT0.35050539
141IRAK20.34959686

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030203.22662316
2Protein export_Homo sapiens_hsa030602.92790804
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.78028518
4Basal transcription factors_Homo sapiens_hsa030222.61058801
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.48153460
6Non-homologous end-joining_Homo sapiens_hsa034502.40940145
7Spliceosome_Homo sapiens_hsa030402.30731238
8Proteasome_Homo sapiens_hsa030502.20748052
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.10873012
10Ribosome_Homo sapiens_hsa030102.07708062
11Cell cycle_Homo sapiens_hsa041102.02987350
12DNA replication_Homo sapiens_hsa030302.00988623
13Butanoate metabolism_Homo sapiens_hsa006501.98939527
14RNA degradation_Homo sapiens_hsa030181.97796851
15Homologous recombination_Homo sapiens_hsa034401.97760228
16Mismatch repair_Homo sapiens_hsa034301.94013679
17Nucleotide excision repair_Homo sapiens_hsa034201.91497292
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.74774303
19RNA transport_Homo sapiens_hsa030131.68399919
20Cardiac muscle contraction_Homo sapiens_hsa042601.67755072
21Base excision repair_Homo sapiens_hsa034101.67205535
22Graft-versus-host disease_Homo sapiens_hsa053321.64681704
23Nicotine addiction_Homo sapiens_hsa050331.58425766
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.58161335
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.54734173
26Pyrimidine metabolism_Homo sapiens_hsa002401.52239997
27Olfactory transduction_Homo sapiens_hsa047401.52177783
28Propanoate metabolism_Homo sapiens_hsa006401.51811548
29Fanconi anemia pathway_Homo sapiens_hsa034601.50242865
30Nitrogen metabolism_Homo sapiens_hsa009101.44432631
31mRNA surveillance pathway_Homo sapiens_hsa030151.43830240
32Parkinsons disease_Homo sapiens_hsa050121.38957495
33Oxidative phosphorylation_Homo sapiens_hsa001901.36974224
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.34738139
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.28581450
36Primary immunodeficiency_Homo sapiens_hsa053401.26144159
37Huntingtons disease_Homo sapiens_hsa050161.21248546
38Tryptophan metabolism_Homo sapiens_hsa003801.18181466
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.18079370
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.17031535
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.15514998
42p53 signaling pathway_Homo sapiens_hsa041151.15401230
43Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.15079757
44Dorso-ventral axis formation_Homo sapiens_hsa043201.14349565
45Morphine addiction_Homo sapiens_hsa050321.13673556
46Collecting duct acid secretion_Homo sapiens_hsa049661.12410778
47Taste transduction_Homo sapiens_hsa047421.11642278
48Epstein-Barr virus infection_Homo sapiens_hsa051691.07443923
49Sphingolipid metabolism_Homo sapiens_hsa006001.03400145
50Maturity onset diabetes of the young_Homo sapiens_hsa049501.03282317
51Selenocompound metabolism_Homo sapiens_hsa004501.02821191
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01610472
53Autoimmune thyroid disease_Homo sapiens_hsa053201.00608254
54Peroxisome_Homo sapiens_hsa041460.98595030
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.96598286
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.95692670
57Ether lipid metabolism_Homo sapiens_hsa005650.93184844
58Antigen processing and presentation_Homo sapiens_hsa046120.93144663
59Purine metabolism_Homo sapiens_hsa002300.91605092
60Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.90547481
61Alzheimers disease_Homo sapiens_hsa050100.90452412
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89221889
63Chemical carcinogenesis_Homo sapiens_hsa052040.89158586
64Caffeine metabolism_Homo sapiens_hsa002320.86799956
65Alcoholism_Homo sapiens_hsa050340.85846386
66T cell receptor signaling pathway_Homo sapiens_hsa046600.85828163
67One carbon pool by folate_Homo sapiens_hsa006700.85687355
68TGF-beta signaling pathway_Homo sapiens_hsa043500.83587280
69Circadian entrainment_Homo sapiens_hsa047130.82663649
70Colorectal cancer_Homo sapiens_hsa052100.82248835
71Oocyte meiosis_Homo sapiens_hsa041140.82221908
72Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80795674
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80634226
74Allograft rejection_Homo sapiens_hsa053300.79866677
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79566823
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78798398
77Viral carcinogenesis_Homo sapiens_hsa052030.78612460
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.78527189
79Primary bile acid biosynthesis_Homo sapiens_hsa001200.76519344
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75107631
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73262798
82Herpes simplex infection_Homo sapiens_hsa051680.73252709
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.72591867
84Sulfur metabolism_Homo sapiens_hsa009200.71966387
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.71370115
86Hepatitis B_Homo sapiens_hsa051610.71330939
87Glutamatergic synapse_Homo sapiens_hsa047240.71183577
88Retinol metabolism_Homo sapiens_hsa008300.70703974
89HTLV-I infection_Homo sapiens_hsa051660.70274370
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69137416
91GABAergic synapse_Homo sapiens_hsa047270.68969820
92Metabolic pathways_Homo sapiens_hsa011000.68937942
93Systemic lupus erythematosus_Homo sapiens_hsa053220.68541057
94Arachidonic acid metabolism_Homo sapiens_hsa005900.65658987
95Axon guidance_Homo sapiens_hsa043600.65267187
96Asthma_Homo sapiens_hsa053100.65190277
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.65175470
98Thyroid cancer_Homo sapiens_hsa052160.64946097
99N-Glycan biosynthesis_Homo sapiens_hsa005100.64898463
100Hematopoietic cell lineage_Homo sapiens_hsa046400.64091705
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64088817
102Type I diabetes mellitus_Homo sapiens_hsa049400.63752736
103Phototransduction_Homo sapiens_hsa047440.63086498
104MicroRNAs in cancer_Homo sapiens_hsa052060.62938631
105Wnt signaling pathway_Homo sapiens_hsa043100.62531714
106Shigellosis_Homo sapiens_hsa051310.62051562
107Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61185211
108Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.59533903
109Hippo signaling pathway_Homo sapiens_hsa043900.57945545
110Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57433917
111Measles_Homo sapiens_hsa051620.56313794
112Glycerolipid metabolism_Homo sapiens_hsa005610.53635945
113Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52004542
114Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51706607
115Pancreatic cancer_Homo sapiens_hsa052120.51435724
116ABC transporters_Homo sapiens_hsa020100.50138609
117Prostate cancer_Homo sapiens_hsa052150.50031150
118Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49691303
119Dopaminergic synapse_Homo sapiens_hsa047280.47292577
120Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46658079
121Rheumatoid arthritis_Homo sapiens_hsa053230.46655208
122Insulin secretion_Homo sapiens_hsa049110.46424698
123Renal cell carcinoma_Homo sapiens_hsa052110.46287922
124Notch signaling pathway_Homo sapiens_hsa043300.45988360
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44851984
126Pathways in cancer_Homo sapiens_hsa052000.44593812
127Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44571037
128Salivary secretion_Homo sapiens_hsa049700.43382261
129Serotonergic synapse_Homo sapiens_hsa047260.42027460
130Basal cell carcinoma_Homo sapiens_hsa052170.41985331
131Calcium signaling pathway_Homo sapiens_hsa040200.41808455
132Regulation of autophagy_Homo sapiens_hsa041400.40212140
133Ras signaling pathway_Homo sapiens_hsa040140.39756653
134NOD-like receptor signaling pathway_Homo sapiens_hsa046210.39713431
135Adherens junction_Homo sapiens_hsa045200.39009925
136Circadian rhythm_Homo sapiens_hsa047100.38721432
137Vitamin B6 metabolism_Homo sapiens_hsa007500.38506676
138Steroid biosynthesis_Homo sapiens_hsa001000.37491649
139Small cell lung cancer_Homo sapiens_hsa052220.37329743
140Vibrio cholerae infection_Homo sapiens_hsa051100.36620721
141Linoleic acid metabolism_Homo sapiens_hsa005910.36474266
142Cysteine and methionine metabolism_Homo sapiens_hsa002700.35792511
143Glutathione metabolism_Homo sapiens_hsa004800.35703266
144Amphetamine addiction_Homo sapiens_hsa050310.35526199
145PI3K-Akt signaling pathway_Homo sapiens_hsa041510.35485421
146Apoptosis_Homo sapiens_hsa042100.35421036
147Malaria_Homo sapiens_hsa051440.35083717
148Ovarian steroidogenesis_Homo sapiens_hsa049130.35029122
149Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.34569979
150Jak-STAT signaling pathway_Homo sapiens_hsa046300.34357206
151Mineral absorption_Homo sapiens_hsa049780.33586556
152Folate biosynthesis_Homo sapiens_hsa007900.33386053
153Hedgehog signaling pathway_Homo sapiens_hsa043400.31775281
154Viral myocarditis_Homo sapiens_hsa054160.31425543
155Renin secretion_Homo sapiens_hsa049240.28777747
156Fatty acid elongation_Homo sapiens_hsa000620.27955157
157Fatty acid degradation_Homo sapiens_hsa000710.27791213

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