FAM207A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of phagocytosis (GO:0050765)5.35412101
2folic acid-containing compound biosynthetic process (GO:0009396)4.93602579
3DNA deamination (GO:0045006)4.75929756
4negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.35915763
5nucleobase biosynthetic process (GO:0046112)4.30623104
6folic acid metabolic process (GO:0046655)4.22033752
7maturation of SSU-rRNA (GO:0030490)4.21978242
8regulation of translational termination (GO:0006449)4.20903394
9glycine metabolic process (GO:0006544)4.19114004
10purine nucleobase biosynthetic process (GO:0009113)3.95005141
11Golgi transport vesicle coating (GO:0048200)3.93279536
12COPI coating of Golgi vesicle (GO:0048205)3.93279536
13maturation of 5.8S rRNA (GO:0000460)3.91082303
14viral transcription (GO:0019083)3.87928674
15translational termination (GO:0006415)3.81548220
16ribosomal small subunit assembly (GO:0000028)3.81544156
17peptidyl-histidine modification (GO:0018202)3.79540183
18deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.76742431
19formation of translation preinitiation complex (GO:0001731)3.72298801
20pteridine-containing compound biosynthetic process (GO:0042559)3.66954661
21translational elongation (GO:0006414)3.62361600
22pentose-phosphate shunt (GO:0006098)3.58088761
23regulation of mammary gland epithelial cell proliferation (GO:0033599)3.57200159
24nucleobase-containing small molecule interconversion (GO:0015949)3.55148423
25pentose metabolic process (GO:0019321)3.53317426
26serine family amino acid biosynthetic process (GO:0009070)3.52304164
27ribosome biogenesis (GO:0042254)3.51639728
28SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.47150635
29antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.44337711
30antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.44337711
31regulation of activation of Janus kinase activity (GO:0010533)3.42736086
32translational initiation (GO:0006413)3.42584035
33ribosome assembly (GO:0042255)3.42032918
34L-serine metabolic process (GO:0006563)3.39051012
35protein targeting to ER (GO:0045047)3.37103613
36DNA unwinding involved in DNA replication (GO:0006268)3.37077653
37histone arginine methylation (GO:0034969)3.34003789
38cotranslational protein targeting to membrane (GO:0006613)3.33205923
39regulation of translational fidelity (GO:0006450)3.31422473
40maternal placenta development (GO:0001893)3.30975660
41mitochondrial DNA metabolic process (GO:0032042)3.26066818
42erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.24075805
43L-phenylalanine metabolic process (GO:0006558)3.24075805
44tetrahydrofolate metabolic process (GO:0046653)3.24006617
45DNA strand elongation involved in DNA replication (GO:0006271)3.22475217
46protein localization to endoplasmic reticulum (GO:0070972)3.21527145
47nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.20914205
48ribonucleoprotein complex biogenesis (GO:0022613)3.19782701
49establishment of protein localization to endoplasmic reticulum (GO:0072599)3.18509381
50serine family amino acid metabolic process (GO:0009069)3.17755532
51regulation of mitochondrial translation (GO:0070129)3.16506520
52folic acid-containing compound metabolic process (GO:0006760)3.14985232
53nucleoside salvage (GO:0043174)3.14789027
54rRNA transcription (GO:0009303)3.14761124
55GDP-mannose metabolic process (GO:0019673)3.11041928
56cellular component biogenesis (GO:0044085)3.10166366
57NADPH regeneration (GO:0006740)3.07028926
58negative regulation of mast cell activation (GO:0033004)3.06497633
59regulation of early endosome to late endosome transport (GO:2000641)3.05509179
60ribosomal large subunit biogenesis (GO:0042273)3.05456926
61viral mRNA export from host cell nucleus (GO:0046784)3.04756574
62DNA replication checkpoint (GO:0000076)3.03666930
63viral life cycle (GO:0019058)3.02277820
64cellular protein complex disassembly (GO:0043624)3.01076797
65pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.00097288
66mitotic nuclear envelope disassembly (GO:0007077)2.98130193
67mitotic chromosome condensation (GO:0007076)2.97291610
68ribosomal small subunit biogenesis (GO:0042274)2.97273762
69UMP metabolic process (GO:0046049)2.96473025
70pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.96473025
71UMP biosynthetic process (GO:0006222)2.96473025
72pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.96473025
73DNA strand elongation (GO:0022616)2.96196795
74pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.95471166
75negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.95254059
76ncRNA 3-end processing (GO:0043628)2.94990428
77oxidative phosphorylation (GO:0006119)2.93727288
78protein targeting to mitochondrion (GO:0006626)2.92727070
79heterochromatin organization (GO:0070828)2.92529437
80tRNA methylation (GO:0030488)2.90362513
81pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.89262683
82protein localization to kinetochore (GO:0034501)2.88618284
83pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.87467519
84mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.86375762
85DNA replication initiation (GO:0006270)2.86300334
86pteridine-containing compound metabolic process (GO:0042558)2.84887303
87protein complex disassembly (GO:0043241)2.83325452
88pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.83133962
89pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.83104505
90serine family amino acid catabolic process (GO:0009071)2.82324604
91negative regulation of RNA splicing (GO:0033119)2.82263331
92DNA replication-dependent nucleosome assembly (GO:0006335)2.82054875
93DNA replication-dependent nucleosome organization (GO:0034723)2.82054875
94nuclear envelope disassembly (GO:0051081)2.81245576
95membrane disassembly (GO:0030397)2.81245576
96negative regulation of mRNA processing (GO:0050686)2.80502415
97telomere maintenance via semi-conservative replication (GO:0032201)2.80022655
98rRNA processing (GO:0006364)2.79046427
99mitotic nuclear envelope reassembly (GO:0007084)2.78914023
100nuclear envelope reassembly (GO:0031468)2.78914023
101UTP biosynthetic process (GO:0006228)2.78871825
102L-phenylalanine catabolic process (GO:0006559)2.76939065
103erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.76939065
104negative regulation of cell size (GO:0045792)2.76338395
105pinocytosis (GO:0006907)2.74190537
106antigen processing and presentation of endogenous antigen (GO:0019883)2.71588423
107nuclear-transcribed mRNA catabolic process (GO:0000956)2.70762973
108establishment of protein localization to mitochondrion (GO:0072655)2.70708805
109one-carbon metabolic process (GO:0006730)2.69299211
110peptidyl-arginine N-methylation (GO:0035246)2.69166028
111peptidyl-arginine methylation (GO:0018216)2.69166028
112rRNA metabolic process (GO:0016072)2.69163486
113macromolecular complex disassembly (GO:0032984)2.69142845
114IMP biosynthetic process (GO:0006188)2.68239620
115positive regulation of nuclease activity (GO:0032075)2.67668808
116transcription from mitochondrial promoter (GO:0006390)2.66779401
117protein targeting to membrane (GO:0006612)2.64494958
118activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.63830702
119translation (GO:0006412)2.63488965
120energy coupled proton transport, down electrochemical gradient (GO:0015985)2.63108328
121ATP synthesis coupled proton transport (GO:0015986)2.63108328
122negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.62437409
123negative regulation of ligase activity (GO:0051352)2.62437409
124T cell apoptotic process (GO:0070231)2.62131855
125pyrimidine-containing compound salvage (GO:0008655)2.62127220
126pyrimidine nucleoside salvage (GO:0043097)2.62127220
127guanosine-containing compound biosynthetic process (GO:1901070)2.60921852
128protein complex localization (GO:0031503)2.60856700
129mRNA catabolic process (GO:0006402)2.60741149
130proteasome assembly (GO:0043248)2.60213456
131negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.59030521
132pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.58855301
133regulation of translational elongation (GO:0006448)2.58086667
134regulation of chromatin binding (GO:0035561)2.58047850
135apoptotic process involved in morphogenesis (GO:0060561)2.57651473
136pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.57143215
137peptidyl-arginine omega-N-methylation (GO:0035247)2.56707615
138negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.55883201
139spliceosomal snRNP assembly (GO:0000387)2.54518254
140pseudouridine synthesis (GO:0001522)2.53153915
141telomere maintenance via recombination (GO:0000722)2.52625781
142modulation by symbiont of host cellular process (GO:0044068)2.52128175
143glucose catabolic process (GO:0006007)2.51646564
144RNA catabolic process (GO:0006401)2.51250514
145folic acid transport (GO:0015884)2.50154561
146regulation of nuclease activity (GO:0032069)2.49975254
147negative regulation of mRNA metabolic process (GO:1903312)2.48674453
148negative regulation of fibrinolysis (GO:0051918)2.48167417
149regulation of protein heterodimerization activity (GO:0043497)2.48059836
150CTP metabolic process (GO:0046036)2.47514542
151anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.44398809
152lysine metabolic process (GO:0006553)2.43026684
153lysine catabolic process (GO:0006554)2.43026684
154proline biosynthetic process (GO:0006561)2.42420069
155tRNA aminoacylation for protein translation (GO:0006418)2.42215078
156protein maturation by protein folding (GO:0022417)2.42179267
157protein localization to chromosome, centromeric region (GO:0071459)2.41463073

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.30293998
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.11491645
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.35485814
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.60620286
5MYC_22102868_ChIP-Seq_BL_Human2.56678519
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.47227198
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42482931
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.41098476
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.31022300
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.30953223
11XRN2_22483619_ChIP-Seq_HELA_Human2.16568379
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.15825860
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.14357333
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.09472546
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.06366073
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.94845367
17EST1_17652178_ChIP-ChIP_JURKAT_Human1.94442753
18VDR_21846776_ChIP-Seq_THP-1_Human1.88396966
19NELFA_20434984_ChIP-Seq_ESCs_Mouse1.82375637
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.82034036
21* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.78834559
22E2F4_17652178_ChIP-ChIP_JURKAT_Human1.75687193
23GABP_19822575_ChIP-Seq_HepG2_Human1.75432197
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.75339755
25PPARA_22158963_ChIP-Seq_LIVER_Mouse1.75199846
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74111935
27TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.73139874
28ESR1_15608294_ChIP-ChIP_MCF-7_Human1.70978869
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68679073
30E2F1_18555785_ChIP-Seq_MESCs_Mouse1.65982322
31VDR_23849224_ChIP-Seq_CD4+_Human1.65103610
32RXR_22158963_ChIP-Seq_LIVER_Mouse1.63817242
33ZFX_18555785_ChIP-Seq_MESCs_Mouse1.59165595
34DCP1A_22483619_ChIP-Seq_HELA_Human1.55411849
35CIITA_25753668_ChIP-Seq_RAJI_Human1.50462867
36DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.48290449
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.47856030
38FOXP3_21729870_ChIP-Seq_TREG_Human1.47620618
39ZNF263_19887448_ChIP-Seq_K562_Human1.47303658
40TET1_21451524_ChIP-Seq_MESCs_Mouse1.45082665
41STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41981357
42KDM5A_27292631_Chip-Seq_BREAST_Human1.40716847
43TP63_17297297_ChIP-ChIP_HaCaT_Human1.39814950
44TTF2_22483619_ChIP-Seq_HELA_Human1.39080601
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38593713
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38292424
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.38015914
48THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37007945
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.36807614
50TFEB_21752829_ChIP-Seq_HELA_Human1.36383806
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.36378395
52CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.36275242
53KLF4_18555785_ChIP-Seq_MESCs_Mouse1.35297150
54FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34231215
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33470386
56TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32799378
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31625619
58ELK3_25401928_ChIP-Seq_HUVEC_Human1.30294080
59NANOG_18555785_ChIP-Seq_MESCs_Mouse1.29438330
60LXR_22292898_ChIP-Seq_THP-1_Human1.28894882
61CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.27955560
62NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.23361194
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.21489094
64KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19803925
65MAF_26560356_Chip-Seq_TH1_Human1.19491603
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.18599687
67RARG_19884340_ChIP-ChIP_MEFs_Mouse1.18372215
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.17364804
69SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.17230702
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.16232696
71UTX_26944678_Chip-Seq_JUKART_Human1.15787448
72CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.15486348
73AR_21909140_ChIP-Seq_LNCAP_Human1.15459608
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15353029
75ATF3_27146783_Chip-Seq_COLON_Human1.13644455
76E2F1_21310950_ChIP-Seq_MCF-7_Human1.12819682
77PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12285467
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11577509
79CTCF_18555785_ChIP-Seq_MESCs_Mouse1.11302844
80KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10745632
81SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.10246111
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09966915
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.09762354
84TCF7_22412390_ChIP-Seq_EML_Mouse1.09649322
85CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08599878
86MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.08520463
87CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08484474
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.08018905
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07647950
90ELF1_20517297_ChIP-Seq_JURKAT_Human1.07568379
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.07449470
92RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.06940481
93CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.05970204
94MAF_26560356_Chip-Seq_TH2_Human1.05287983
95KDM2B_26808549_Chip-Seq_SUP-B15_Human1.05234533
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.04420835
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.03377519
98THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.02836529
99TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02747065
100KDM2B_26808549_Chip-Seq_DND41_Human1.02364216
101MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02113628
102SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01981866
103BCOR_27268052_Chip-Seq_Bcells_Human1.01924109
104GATA1_22383799_ChIP-Seq_G1ME_Mouse1.01921792
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.01418344
106RACK7_27058665_Chip-Seq_MCF-7_Human1.00999142
107FOXP1_21924763_ChIP-Seq_HESCs_Human1.00445332
108ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.98774732
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98692047
110CTCF_27219007_Chip-Seq_ERYTHROID_Human0.98257998
111BCL6_27268052_Chip-Seq_Bcells_Human0.98212489
112ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.98165663
113SRF_21415370_ChIP-Seq_HL-1_Mouse0.98042835
114E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97935423
115NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97673306
116PU.1_20513432_ChIP-Seq_Bcells_Mouse0.97532506
117P68_20966046_ChIP-Seq_HELA_Human0.97348387
118KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97120184
119VDR_24763502_ChIP-Seq_THP-1_Human0.96593071
120CLOCK_20551151_ChIP-Seq_293T_Human0.96521276
121FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.96202942
122NCOR1_26117541_ChIP-Seq_K562_Human0.95905289
123SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.95840050

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.90711489
2MP0009840_abnormal_foam_cell3.42433079
3MP0005451_abnormal_body_composition3.36180787
4MP0002139_abnormal_hepatobiliary_system3.29555991
5MP0005360_urolithiasis3.28934320
6MP0004957_abnormal_blastocyst_morpholog3.03303748
7MP0003111_abnormal_nucleus_morphology2.93701764
8MP0003806_abnormal_nucleotide_metabolis2.65862155
9MP0010352_gastrointestinal_tract_polyps2.50000145
10MP0005365_abnormal_bile_salt2.47715140
11MP0005085_abnormal_gallbladder_physiolo2.38091818
12MP0003705_abnormal_hypodermis_morpholog2.28799075
13MP0003077_abnormal_cell_cycle2.22321230
14MP0000015_abnormal_ear_pigmentation2.19906519
15MP0003300_gastrointestinal_ulcer2.03554253
16MP0003646_muscle_fatigue2.03237895
17MP0005058_abnormal_lysosome_morphology2.02156308
18MP0000372_irregular_coat_pigmentation2.01913606
19MP0004185_abnormal_adipocyte_glucose2.00484850
20MP0001730_embryonic_growth_arrest1.97592022
21MP0000678_abnormal_parathyroid_gland1.97571778
22MP0005075_abnormal_melanosome_morpholog1.96112500
23MP0004381_abnormal_hair_follicle1.89225121
24MP0009333_abnormal_splenocyte_physiolog1.89190916
25MP0003191_abnormal_cellular_cholesterol1.82324158
26MP0010094_abnormal_chromosome_stability1.78969207
27MP0003303_peritoneal_inflammation1.77352184
28MP0002396_abnormal_hematopoietic_system1.76670410
29MP0008007_abnormal_cellular_replicative1.67727081
30MP0008260_abnormal_autophagy1.64626468
31MP0004233_abnormal_muscle_weight1.63989576
32MP0009379_abnormal_foot_pigmentation1.57789928
33MP0003786_premature_aging1.57159095
34MP0010307_abnormal_tumor_latency1.54923897
35MP0005220_abnormal_exocrine_pancreas1.54605564
36MP0000609_abnormal_liver_physiology1.53402305
37MP0001661_extended_life_span1.50683873
38MP0003763_abnormal_thymus_physiology1.49575568
39MP0000490_abnormal_crypts_of1.49222714
40MP0005083_abnormal_biliary_tract1.49159596
41MP0000350_abnormal_cell_proliferation1.49141353
42MP0005076_abnormal_cell_differentiation1.48782070
43MP0003252_abnormal_bile_duct1.48232076
44MP0002138_abnormal_hepatobiliary_system1.47951481
45MP0005501_abnormal_skin_physiology1.47496827
46MP0008875_abnormal_xenobiotic_pharmacok1.41131743
47MP0002080_prenatal_lethality1.40078408
48MP0010329_abnormal_lipoprotein_level1.39166142
49MP0000598_abnormal_liver_morphology1.37531102
50MP0000685_abnormal_immune_system1.37175020
51MP0003436_decreased_susceptibility_to1.36721036
52MP0003656_abnormal_erythrocyte_physiolo1.36363279
53MP0002796_impaired_skin_barrier1.35498085
54MP0002163_abnormal_gland_morphology1.29524402
55MP0001697_abnormal_embryo_size1.28070189
56MP0006035_abnormal_mitochondrial_morpho1.26276604
57MP0002019_abnormal_tumor_incidence1.24827680
58MP0002722_abnormal_immune_system1.24763288
59MP0001666_abnormal_nutrient_absorption1.24742059
60MP0001672_abnormal_embryogenesis/_devel1.23303159
61MP0005380_embryogenesis_phenotype1.23303159
62MP0005397_hematopoietic_system_phenotyp1.23224918
63MP0001545_abnormal_hematopoietic_system1.23224918
64MP0005332_abnormal_amino_acid1.23034993
65MP0002088_abnormal_embryonic_growth/wei1.22827358
66MP0003984_embryonic_growth_retardation1.22087686
67MP0009643_abnormal_urine_homeostasis1.21997094
68MP0005408_hypopigmentation1.21403572
69MP0003186_abnormal_redox_activity1.19810974
70MP0002089_abnormal_postnatal_growth/wei1.19432545
71MP0002398_abnormal_bone_marrow1.18826615
72MP0005319_abnormal_enzyme/_coenzyme1.18394120
73MP0003172_abnormal_lysosome_physiology1.18331524
74MP0000689_abnormal_spleen_morphology1.16730677
75MP0009672_abnormal_birth_weight1.15506910
76MP0000313_abnormal_cell_death1.15089732
77MP0000703_abnormal_thymus_morphology1.14333554
78MP0004808_abnormal_hematopoietic_stem1.12879147
79MP0003453_abnormal_keratinocyte_physiol1.12842360
80MP0005023_abnormal_wound_healing1.11706923
81MP0000358_abnormal_cell_content/1.11516064
82MP0002086_abnormal_extraembryonic_tissu1.11202153
83MP0001853_heart_inflammation1.09240022
84MP0008932_abnormal_embryonic_tissue1.08383970
85MP0005330_cardiomyopathy1.07187772
86MP0000858_altered_metastatic_potential1.06975958
87MP0002249_abnormal_larynx_morphology1.06843432
88MP0001849_ear_inflammation1.06339407
89MP0002075_abnormal_coat/hair_pigmentati1.05026904
90MP0003566_abnormal_cell_adhesion1.04465839
91MP0008058_abnormal_DNA_repair1.03996030
92MP0005666_abnormal_adipose_tissue1.03994823
93MP0003866_abnormal_defecation1.01936856
94MP0009278_abnormal_bone_marrow1.01875640
95MP0005464_abnormal_platelet_physiology1.01810806
96MP0003221_abnormal_cardiomyocyte_apopto1.01638062
97MP0002429_abnormal_blood_cell1.01361960
98MP0001186_pigmentation_phenotype1.00426977
99MP0006036_abnormal_mitochondrial_physio0.99909424
100MP0000371_diluted_coat_color0.99458274
101MP0000343_altered_response_to0.98864666
102MP0000733_abnormal_muscle_development0.97133317
103MP0004858_abnormal_nervous_system0.95903728
104MP0000759_abnormal_skeletal_muscle0.95872532
105MP0001881_abnormal_mammary_gland0.95613166
106MP0003123_paternal_imprinting0.95553756
107MP0009053_abnormal_anal_canal0.95132511
108MP0002132_abnormal_respiratory_system0.94631719
109MP0003119_abnormal_digestive_system0.94433519
110MP0002653_abnormal_ependyma_morphology0.93265426
111MP0005623_abnormal_meninges_morphology0.93224457
112MP0002085_abnormal_embryonic_tissue0.91542584
113MP0001944_abnormal_pancreas_morphology0.90351559
114MP0004197_abnormal_fetal_growth/weight/0.90070730
115MP0005670_abnormal_white_adipose0.89914026
116MP0000750_abnormal_muscle_regeneration0.89582719
117MP0000716_abnormal_immune_system0.88697046
118MP0000003_abnormal_adipose_tissue0.88670343
119MP0001727_abnormal_embryo_implantation0.87666717
120MP0000477_abnormal_intestine_morphology0.87119484
121MP0005375_adipose_tissue_phenotype0.85878266
122MP0002084_abnormal_developmental_patter0.84275168
123MP0003136_yellow_coat_color0.84031650
124MP0005257_abnormal_intraocular_pressure0.83429541
125MP0002269_muscular_atrophy0.82728557
126MP0005621_abnormal_cell_physiology0.82085685
127MP0000604_amyloidosis0.81263489
128MP0002405_respiratory_system_inflammati0.80792572
129MP0001348_abnormal_lacrimal_gland0.80474710
130MP0001800_abnormal_humoral_immune0.79981561
131MP0000747_muscle_weakness0.79915922
132MP0002092_abnormal_eye_morphology0.78818615
133MP0008469_abnormal_protein_level0.78295419
134MP0006054_spinal_hemorrhage0.78118619
135MP0005384_cellular_phenotype0.77022555
136MP0010155_abnormal_intestine_physiology0.75954509
137MP0004947_skin_inflammation0.75013552
138MP0005636_abnormal_mineral_homeostasis0.75012745
139MP0004087_abnormal_muscle_fiber0.74753633
140MP0010030_abnormal_orbit_morphology0.74439943
141MP0002693_abnormal_pancreas_physiology0.73861985
142MP0008961_abnormal_basal_metabolism0.73812344
143MP0001845_abnormal_inflammatory_respons0.73750178
144MP0002877_abnormal_melanocyte_morpholog0.72863414
145MP0009931_abnormal_skin_appearance0.72792767
146MP0002060_abnormal_skin_morphology0.72225831

Predicted human phenotypes

RankGene SetZ-score
1Microvesicular hepatic steatosis (HP:0001414)4.77720070
2Testicular atrophy (HP:0000029)4.10489349
3Abnormality of aromatic amino acid family metabolism (HP:0004338)4.03523895
4Abnormality of monocarboxylic acid metabolism (HP:0010996)3.64199024
5Aplasia/Hypoplasia of the sacrum (HP:0008517)3.43017812
6Progressive muscle weakness (HP:0003323)3.10293112
7Overriding aorta (HP:0002623)3.08771582
8Hypobetalipoproteinemia (HP:0003563)3.01378044
9Microretrognathia (HP:0000308)2.93507963
10Elfin facies (HP:0004428)2.92488864
11Xanthomatosis (HP:0000991)2.90508912
12Renovascular hypertension (HP:0100817)2.89923079
13Deep venous thrombosis (HP:0002625)2.88448819
14Multiple enchondromatosis (HP:0005701)2.88260818
15Gout (HP:0001997)2.86670407
16Abnormality of cells of the erythroid lineage (HP:0012130)2.85104551
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.82753776
18Abnormality of glycolysis (HP:0004366)2.82116886
19Progressive external ophthalmoplegia (HP:0000590)2.81901366
20Abnormality of pyrimidine metabolism (HP:0004353)2.79506106
21Hyperglycinemia (HP:0002154)2.67130015
22Thrombocytosis (HP:0001894)2.64639675
23Spastic diplegia (HP:0001264)2.64556590
24Abnormality of the Achilles tendon (HP:0005109)2.64450338
25Abnormal mitochondria in muscle tissue (HP:0008316)2.63379392
26Abnormal number of erythroid precursors (HP:0012131)2.63242606
27Renal duplication (HP:0000075)2.59180775
28Generalized amyotrophy (HP:0003700)2.56093638
29Increased serum pyruvate (HP:0003542)2.53517301
30Broad distal phalanx of finger (HP:0009836)2.53378426
31Late onset (HP:0003584)2.47863310
32Achilles tendon contracture (HP:0001771)2.47277157
33Reticulocytopenia (HP:0001896)2.47006561
34Abnormality of the umbilical cord (HP:0010881)2.44196313
35Hand muscle atrophy (HP:0009130)2.42931640
36Aplastic anemia (HP:0001915)2.42163974
37Abnormality of reticulocytes (HP:0004312)2.40420253
38Severe visual impairment (HP:0001141)2.40160890
39Hypoglycemic coma (HP:0001325)2.38582617
40Macrocytic anemia (HP:0001972)2.37651116
41Increased connective tissue (HP:0009025)2.36890481
42Reticulocytosis (HP:0001923)2.36715455
43Acute necrotizing encephalopathy (HP:0006965)2.35978967
443-Methylglutaconic aciduria (HP:0003535)2.33629840
45Abnormal neuron morphology (HP:0012757)2.33199350
46Abnormality of the motor neurons (HP:0002450)2.33199350
47Sensory axonal neuropathy (HP:0003390)2.32471623
48Hypergonadotropic hypogonadism (HP:0000815)2.30249781
49Selective tooth agenesis (HP:0001592)2.29300247
50Protrusio acetabuli (HP:0003179)2.27609838
51Abnormality of the lower motor neuron (HP:0002366)2.25884328
52Increased intramyocellular lipid droplets (HP:0012240)2.23727001
53Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.23309060
54Hypokinesia (HP:0002375)2.22654954
55Hyperammonemia (HP:0001987)2.22111999
56Atrophy/Degeneration involving motor neurons (HP:0007373)2.21558760
57Increased muscle lipid content (HP:0009058)2.21440236
58Degeneration of anterior horn cells (HP:0002398)2.19932715
59Abnormality of the anterior horn cell (HP:0006802)2.19932715
60Abnormal umbilical cord blood vessels (HP:0011403)2.18414962
61Single umbilical artery (HP:0001195)2.18414962
62Abnormality of the fetal cardiovascular system (HP:0010948)2.18414962
63Intrahepatic cholestasis (HP:0001406)2.18393726
64Rough bone trabeculation (HP:0100670)2.17492061
65Trismus (HP:0000211)2.17032442
66Paralysis (HP:0003470)2.16533783
67Orthostatic hypotension (HP:0001278)2.15986023
68Abnormality of transition element cation homeostasis (HP:0011030)2.14672834
69Angiofibromas (HP:0010615)2.14492231
70Adenoma sebaceum (HP:0009720)2.14492231
71Abnormal gallbladder physiology (HP:0012438)2.14354682
72Cholecystitis (HP:0001082)2.14354682
73Cerebral hypomyelination (HP:0006808)2.13986909
74Exercise intolerance (HP:0003546)2.13716820
75Acute encephalopathy (HP:0006846)2.12589747
76Oral leukoplakia (HP:0002745)2.09917047
77Abnormality of the common coagulation pathway (HP:0010990)2.09909463
78Ketosis (HP:0001946)2.09327541
79Ulnar bowing (HP:0003031)2.08826670
80Breast hypoplasia (HP:0003187)2.07705699
81Global brain atrophy (HP:0002283)2.06445867
82Distal upper limb amyotrophy (HP:0007149)2.06219106
83Upper limb amyotrophy (HP:0009129)2.06219106
84Distal lower limb amyotrophy (HP:0008944)2.05984792
85Pallor (HP:0000980)2.05087888
86Decreased activity of mitochondrial respiratory chain (HP:0008972)2.04874133
87Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.04874133
88Personality changes (HP:0000751)2.03920780
89Ankle contracture (HP:0006466)2.03467387
90Abnormality of glycine metabolism (HP:0010895)2.02862031
91Abnormality of serine family amino acid metabolism (HP:0010894)2.02862031
92Abnormal cartilage morphology (HP:0002763)2.01749850
93Premature skin wrinkling (HP:0100678)2.00619623
94Dysphonia (HP:0001618)2.00461856
95Nonimmune hydrops fetalis (HP:0001790)1.99774020
96Ependymoma (HP:0002888)1.98313429
97Abnormality of the distal phalanges of the toes (HP:0010182)1.97809233
98Megaloblastic anemia (HP:0001889)1.97761150
99Nasal polyposis (HP:0100582)1.97400496
100Increased serum ferritin (HP:0003281)1.96869995
101Carpal bone hypoplasia (HP:0001498)1.96668039
102Chromosomal breakage induced by crosslinking agents (HP:0003221)1.95726194
103Increased CSF lactate (HP:0002490)1.94656615
104Hypertensive crisis (HP:0100735)1.92372495
105Flat cornea (HP:0007720)1.91583848
106Abnormality of glutamine family amino acid metabolism (HP:0010902)1.91512077
107Abnormality of nucleobase metabolism (HP:0010932)1.90965402
108Abnormality of iron homeostasis (HP:0011031)1.89900444
109Distal lower limb muscle weakness (HP:0009053)1.89226692
110Hyperglycinuria (HP:0003108)1.88830160
111Abnormality of the pancreatic islet cells (HP:0006476)1.88356786
112Abnormality of endocrine pancreas physiology (HP:0012093)1.88356786
113Micronodular cirrhosis (HP:0001413)1.86485912
114Ileus (HP:0002595)1.85077574
115Amyotrophic lateral sclerosis (HP:0007354)1.84697819
116Centrally nucleated skeletal muscle fibers (HP:0003687)1.83974891
117Secondary amenorrhea (HP:0000869)1.83618766
118Impaired proprioception (HP:0010831)1.83610987
119Hyperacusis (HP:0010780)1.83025737
120Mitochondrial inheritance (HP:0001427)1.82977777
121Increased serum lactate (HP:0002151)1.82069508
122Progressive hearing impairment (HP:0001730)1.81592025
123Elbow flexion contracture (HP:0002987)1.81376435
12411 pairs of ribs (HP:0000878)1.80580844
125Septate vagina (HP:0001153)1.80340366
126Delayed CNS myelination (HP:0002188)1.79257948
127Ragged-red muscle fibers (HP:0003200)1.79109659
128Vertebral compression fractures (HP:0002953)1.79020211
129Neoplasm of the pancreas (HP:0002894)1.78981880
130Neonatal onset (HP:0003623)1.78944789
131IgM deficiency (HP:0002850)1.77844320
132Increased nuchal translucency (HP:0010880)1.77322599
133Gastrointestinal dysmotility (HP:0002579)1.77162295
134Pelvic girdle muscle weakness (HP:0003749)1.76831675
135Impaired platelet aggregation (HP:0003540)1.76222598
136Abnormal platelet function (HP:0011869)1.76222598
137Premature ovarian failure (HP:0008209)1.75543911
138Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.75524563
139Abnormality of the nasal mucosa (HP:0000433)1.74075289
140Abnormality of the intrinsic pathway (HP:0010989)1.73108445
141Hypolipoproteinemia (HP:0010981)1.71622709
142Birth length less than 3rd percentile (HP:0003561)1.71351164
143Polycythemia (HP:0001901)1.71103953
144Abnormality of sulfur amino acid metabolism (HP:0004339)1.70927392
145Insulin resistance (HP:0000855)1.70412495
146Irritability (HP:0000737)1.70370706
147Axonal loss (HP:0003447)1.69482469
148Patellar dislocation (HP:0002999)1.69358975
149Cerebral aneurysm (HP:0004944)1.69182180
150Abnormal trabecular bone morphology (HP:0100671)1.69121793
151Increased variability in muscle fiber diameter (HP:0003557)1.68699821
152Entropion (HP:0000621)1.68592204
153Myopathic facies (HP:0002058)1.67600208
154Cleft eyelid (HP:0000625)1.67273590
155Abnormalities of placenta or umbilical cord (HP:0001194)1.65992396
156Limb hypertonia (HP:0002509)1.65933200
157Abnormality of skeletal muscle fiber size (HP:0012084)1.65615433
158Abnormality of T cell physiology (HP:0011840)1.65568612
159Insomnia (HP:0100785)1.62092854
160Slender long bone (HP:0003100)1.61219499
161Sparse eyelashes (HP:0000653)1.61006884
162Squamous cell carcinoma (HP:0002860)1.60825053
163Ocular albinism (HP:0001107)1.60156716
164Hyperbilirubinemia (HP:0002904)1.59946766
165Prolonged partial thromboplastin time (HP:0003645)1.59442621
166Petechiae (HP:0000967)1.59087743
167Colon cancer (HP:0003003)1.58763265
168Increased density of long bones (HP:0006392)1.58613272
169Cerebral edema (HP:0002181)1.58567250
170Dysautonomia (HP:0002459)1.58487357
171Albinism (HP:0001022)1.56522723
172Respiratory difficulties (HP:0002880)1.55887420
173Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.55641493

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.32201633
2SMG13.36037610
3ERN13.19766884
4TESK23.07876465
5PKN22.99675311
6TRIB32.78634992
7VRK22.71526864
8MAP3K102.58736954
9IRAK32.55799195
10CDK82.54005838
11NME22.48311315
12SCYL22.34951565
13WEE12.34555280
14EEF2K2.32094998
15DYRK32.27597074
16EIF2AK12.26864026
17FLT32.08599137
18MAP4K12.00173276
19ICK1.93190545
20NEK21.92432383
21BCKDK1.90129799
22PASK1.84506639
23TESK11.83633390
24RPS6KA41.81902724
25EPHA21.77978370
26KDR1.65532489
27MAP3K111.62603929
28TSSK61.55581945
29MAP3K81.55220300
30CDC42BPA1.53048102
31GRK61.49492197
32PRPF4B1.48508707
33NEK11.45881340
34RPS6KB21.42743721
35FGFR41.42193241
36RIPK11.34989143
37PAK41.34680904
38LRRK21.30604995
39PIM21.28037010
40CLK11.26317281
41ZAP701.25837587
42IRAK41.17835875
43CDK41.14010304
44TLK11.13411797
45STK101.09722912
46TTK1.03871526
47AURKA1.00536879
48CDC70.99098154
49TYK20.98659033
50PTK60.96019041
51BRSK20.94109957
52MAP2K20.92866999
53SIK10.92009600
54TBK10.91819197
55PLK10.89765760
56PBK0.88184256
57EIF2AK30.86119735
58BRSK10.84958821
59MAP2K30.84763391
60ALK0.84312164
61LMTK20.83059907
62PLK40.82633856
63MAPKAPK30.81424012
64CDK70.79079563
65MST1R0.77634832
66PRKD20.77340720
67AURKB0.77217440
68MELK0.70028608
69BTK0.68887240
70STK40.68790018
71PAK10.67691858
72VRK10.67200047
73JAK30.66887164
74MAP3K30.66848994
75MST40.65480737
76LIMK10.65146221
77MTOR0.64023103
78SRPK10.63398533
79MAPKAPK20.62162460
80ACVR1B0.61134522
81TAOK10.60849243
82PIM10.58084410
83PAK20.57656247
84MUSK0.57041704
85PTK20.55291380
86ILK0.54846820
87HIPK20.54676410
88BRAF0.54454227
89AKT20.54377699
90MAPK110.54262298
91PRKCI0.52833261
92PRKG20.49892311
93ABL20.49625666
94ATR0.48483725
95MAP3K10.48251191
96DAPK10.48142805
97DAPK30.47572457
98KSR20.47387197
99DYRK1B0.46564130
100PDPK10.45271140
101CHEK10.44988425
102TAOK20.44229643
103NME10.44090111
104TGFBR10.41379284
105CSF1R0.41002750
106CDK90.38442632
107CDK20.37936885
108CHEK20.37654410
109RAF10.37455279
110STK160.35757168
111CSNK2A20.35261890
112TTN0.35120415
113CSNK2A10.34185868
114PDGFRA0.32678125
115CDK11A0.32436426
116ARAF0.31984031
117RPS6KA10.31741578
118SIK20.31467090
119IRAK20.31395637
120JAK20.30145457
121CDK10.27674672
122RPS6KA50.27106147
123CDK60.26600775
124BLK0.26474072
125LATS20.25769118
126CDK120.25442286
127CSK0.25436225
128CDK150.25346516
129RPS6KC10.24108556
130RPS6KL10.24108556

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.18429647
2Ribosome_Homo sapiens_hsa030102.96444336
3One carbon pool by folate_Homo sapiens_hsa006702.63402332
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.54631618
5Proteasome_Homo sapiens_hsa030502.54095166
6Selenocompound metabolism_Homo sapiens_hsa004502.32255428
7Folate biosynthesis_Homo sapiens_hsa007902.27939178
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.27138590
9Spliceosome_Homo sapiens_hsa030402.15804508
10Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.13652765
11Mismatch repair_Homo sapiens_hsa034302.12550000
12RNA transport_Homo sapiens_hsa030132.09156628
13Sulfur relay system_Homo sapiens_hsa041222.08502420
14Primary bile acid biosynthesis_Homo sapiens_hsa001202.07907601
15Drug metabolism - other enzymes_Homo sapiens_hsa009832.06228675
16Pentose phosphate pathway_Homo sapiens_hsa000302.05350997
17Biosynthesis of amino acids_Homo sapiens_hsa012302.03560694
18Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.02985179
19RNA polymerase_Homo sapiens_hsa030201.96851379
20Pyrimidine metabolism_Homo sapiens_hsa002401.95064669
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.90434572
22Cyanoamino acid metabolism_Homo sapiens_hsa004601.82321149
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.76833463
24Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.75991353
25Base excision repair_Homo sapiens_hsa034101.75154154
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.61327059
27Parkinsons disease_Homo sapiens_hsa050121.57828574
28Oxidative phosphorylation_Homo sapiens_hsa001901.52678354
29Nucleotide excision repair_Homo sapiens_hsa034201.48887407
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.47985951
31Carbon metabolism_Homo sapiens_hsa012001.45476955
32Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.37360863
33Nitrogen metabolism_Homo sapiens_hsa009101.36871771
34Vitamin B6 metabolism_Homo sapiens_hsa007501.36674306
35Arginine biosynthesis_Homo sapiens_hsa002201.33693811
36Cell cycle_Homo sapiens_hsa041101.33456941
37Huntingtons disease_Homo sapiens_hsa050161.20810056
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.17706299
39Fructose and mannose metabolism_Homo sapiens_hsa000511.15342034
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.12844193
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.10742802
42p53 signaling pathway_Homo sapiens_hsa041151.07776820
43Antigen processing and presentation_Homo sapiens_hsa046121.06423447
44Tryptophan metabolism_Homo sapiens_hsa003801.06392226
45Protein export_Homo sapiens_hsa030601.03243903
46Galactose metabolism_Homo sapiens_hsa000521.00598895
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.97282996
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96928731
49Pentose and glucuronate interconversions_Homo sapiens_hsa000400.95224675
50Bladder cancer_Homo sapiens_hsa052190.95041610
51Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.93168369
52mRNA surveillance pathway_Homo sapiens_hsa030150.91214128
53Caffeine metabolism_Homo sapiens_hsa002320.89619594
54RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.85328206
55Fanconi anemia pathway_Homo sapiens_hsa034600.83727444
56Epstein-Barr virus infection_Homo sapiens_hsa051690.83720753
57Systemic lupus erythematosus_Homo sapiens_hsa053220.83040568
58Alzheimers disease_Homo sapiens_hsa050100.82497022
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81220221
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.78407616
61Homologous recombination_Homo sapiens_hsa034400.78398425
62Pyruvate metabolism_Homo sapiens_hsa006200.77545424
63Viral carcinogenesis_Homo sapiens_hsa052030.75535029
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70710843
65Thyroid cancer_Homo sapiens_hsa052160.70588510
66Non-homologous end-joining_Homo sapiens_hsa034500.70123647
67Pancreatic cancer_Homo sapiens_hsa052120.68812430
68N-Glycan biosynthesis_Homo sapiens_hsa005100.67082845
69Phenylalanine metabolism_Homo sapiens_hsa003600.66282173
70Primary immunodeficiency_Homo sapiens_hsa053400.64929515
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64163813
72Legionellosis_Homo sapiens_hsa051340.63156088
73Fat digestion and absorption_Homo sapiens_hsa049750.62763921
74Fatty acid elongation_Homo sapiens_hsa000620.62497196
75Shigellosis_Homo sapiens_hsa051310.61348696
76Chronic myeloid leukemia_Homo sapiens_hsa052200.60304209
77Small cell lung cancer_Homo sapiens_hsa052220.60132076
78B cell receptor signaling pathway_Homo sapiens_hsa046620.58348439
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58327175
80RNA degradation_Homo sapiens_hsa030180.56779386
81Complement and coagulation cascades_Homo sapiens_hsa046100.56731669
82Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.55530431
83HTLV-I infection_Homo sapiens_hsa051660.54903843
84Glutathione metabolism_Homo sapiens_hsa004800.54900900
85Arginine and proline metabolism_Homo sapiens_hsa003300.54163548
86Apoptosis_Homo sapiens_hsa042100.54065201
87Vibrio cholerae infection_Homo sapiens_hsa051100.53739093
88Fatty acid degradation_Homo sapiens_hsa000710.53042660
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52210126
90Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.51227415
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.50953877
92Purine metabolism_Homo sapiens_hsa002300.50744136
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.49733845
94Acute myeloid leukemia_Homo sapiens_hsa052210.49036612
95Peroxisome_Homo sapiens_hsa041460.48702957
96Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47228330
97Herpes simplex infection_Homo sapiens_hsa051680.47049333
98Butanoate metabolism_Homo sapiens_hsa006500.42192387
99Bile secretion_Homo sapiens_hsa049760.40879281
100Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40274642
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40173663
102Prion diseases_Homo sapiens_hsa050200.39374624
103beta-Alanine metabolism_Homo sapiens_hsa004100.39204194
104Notch signaling pathway_Homo sapiens_hsa043300.38925254
105Other glycan degradation_Homo sapiens_hsa005110.38885101
106Basal transcription factors_Homo sapiens_hsa030220.35146470
107Histidine metabolism_Homo sapiens_hsa003400.34677044
108Sulfur metabolism_Homo sapiens_hsa009200.34103929
109Tyrosine metabolism_Homo sapiens_hsa003500.33792134
110VEGF signaling pathway_Homo sapiens_hsa043700.32693606
111Viral myocarditis_Homo sapiens_hsa054160.31960834
112mTOR signaling pathway_Homo sapiens_hsa041500.30403737
113Metabolic pathways_Homo sapiens_hsa011000.27713752
114Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26873975
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26734972
116MicroRNAs in cancer_Homo sapiens_hsa052060.26519639
117Lysosome_Homo sapiens_hsa041420.26447072
118Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26053862
119Insulin resistance_Homo sapiens_hsa049310.25443187
120Melanoma_Homo sapiens_hsa052180.24965350
121Non-small cell lung cancer_Homo sapiens_hsa052230.23552456
122Measles_Homo sapiens_hsa051620.22913171
123Hepatitis B_Homo sapiens_hsa051610.22786068
124Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.22754887
125Glycosaminoglycan degradation_Homo sapiens_hsa005310.22550550
126Starch and sucrose metabolism_Homo sapiens_hsa005000.20893695
127Alcoholism_Homo sapiens_hsa050340.20312598
128AMPK signaling pathway_Homo sapiens_hsa041520.20034517

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