Rank | Gene Set | Z-score |
---|---|---|
1 | negative regulation of phagocytosis (GO:0050765) | 5.35412101 |
2 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.93602579 |
3 | DNA deamination (GO:0045006) | 4.75929756 |
4 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.35915763 |
5 | nucleobase biosynthetic process (GO:0046112) | 4.30623104 |
6 | folic acid metabolic process (GO:0046655) | 4.22033752 |
7 | maturation of SSU-rRNA (GO:0030490) | 4.21978242 |
8 | regulation of translational termination (GO:0006449) | 4.20903394 |
9 | glycine metabolic process (GO:0006544) | 4.19114004 |
10 | purine nucleobase biosynthetic process (GO:0009113) | 3.95005141 |
11 | COPI coating of Golgi vesicle (GO:0048205) | 3.93279536 |
12 | Golgi transport vesicle coating (GO:0048200) | 3.93279536 |
13 | maturation of 5.8S rRNA (GO:0000460) | 3.91082303 |
14 | viral transcription (GO:0019083) | 3.87928674 |
15 | translational termination (GO:0006415) | 3.81548220 |
16 | ribosomal small subunit assembly (GO:0000028) | 3.81544156 |
17 | peptidyl-histidine modification (GO:0018202) | 3.79540183 |
18 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.76742431 |
19 | formation of translation preinitiation complex (GO:0001731) | 3.72298801 |
20 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.66954661 |
21 | translational elongation (GO:0006414) | 3.62361600 |
22 | pentose-phosphate shunt (GO:0006098) | 3.58088761 |
23 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.57200159 |
24 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.55148423 |
25 | pentose metabolic process (GO:0019321) | 3.53317426 |
26 | serine family amino acid biosynthetic process (GO:0009070) | 3.52304164 |
27 | ribosome biogenesis (GO:0042254) | 3.51639728 |
28 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.47150635 |
29 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.44337711 |
30 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.44337711 |
31 | regulation of activation of Janus kinase activity (GO:0010533) | 3.42736086 |
32 | translational initiation (GO:0006413) | 3.42584035 |
33 | ribosome assembly (GO:0042255) | 3.42032918 |
34 | L-serine metabolic process (GO:0006563) | 3.39051012 |
35 | protein targeting to ER (GO:0045047) | 3.37103613 |
36 | DNA unwinding involved in DNA replication (GO:0006268) | 3.37077653 |
37 | histone arginine methylation (GO:0034969) | 3.34003789 |
38 | cotranslational protein targeting to membrane (GO:0006613) | 3.33205923 |
39 | regulation of translational fidelity (GO:0006450) | 3.31422473 |
40 | maternal placenta development (GO:0001893) | 3.30975660 |
41 | mitochondrial DNA metabolic process (GO:0032042) | 3.26066818 |
42 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.24075805 |
43 | L-phenylalanine metabolic process (GO:0006558) | 3.24075805 |
44 | tetrahydrofolate metabolic process (GO:0046653) | 3.24006617 |
45 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.22475217 |
46 | protein localization to endoplasmic reticulum (GO:0070972) | 3.21527145 |
47 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.20914205 |
48 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.19782701 |
49 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.18509381 |
50 | serine family amino acid metabolic process (GO:0009069) | 3.17755532 |
51 | regulation of mitochondrial translation (GO:0070129) | 3.16506520 |
52 | folic acid-containing compound metabolic process (GO:0006760) | 3.14985232 |
53 | nucleoside salvage (GO:0043174) | 3.14789027 |
54 | rRNA transcription (GO:0009303) | 3.14761124 |
55 | GDP-mannose metabolic process (GO:0019673) | 3.11041928 |
56 | cellular component biogenesis (GO:0044085) | 3.10166366 |
57 | NADPH regeneration (GO:0006740) | 3.07028926 |
58 | negative regulation of mast cell activation (GO:0033004) | 3.06497633 |
59 | regulation of early endosome to late endosome transport (GO:2000641) | 3.05509179 |
60 | ribosomal large subunit biogenesis (GO:0042273) | 3.05456926 |
61 | viral mRNA export from host cell nucleus (GO:0046784) | 3.04756574 |
62 | DNA replication checkpoint (GO:0000076) | 3.03666930 |
63 | viral life cycle (GO:0019058) | 3.02277820 |
64 | cellular protein complex disassembly (GO:0043624) | 3.01076797 |
65 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.00097288 |
66 | mitotic nuclear envelope disassembly (GO:0007077) | 2.98130193 |
67 | mitotic chromosome condensation (GO:0007076) | 2.97291610 |
68 | ribosomal small subunit biogenesis (GO:0042274) | 2.97273762 |
69 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.96473025 |
70 | UMP metabolic process (GO:0046049) | 2.96473025 |
71 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.96473025 |
72 | UMP biosynthetic process (GO:0006222) | 2.96473025 |
73 | DNA strand elongation (GO:0022616) | 2.96196795 |
74 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.95471166 |
75 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.95254059 |
76 | ncRNA 3-end processing (GO:0043628) | 2.94990428 |
77 | oxidative phosphorylation (GO:0006119) | 2.93727288 |
78 | protein targeting to mitochondrion (GO:0006626) | 2.92727070 |
79 | heterochromatin organization (GO:0070828) | 2.92529437 |
80 | tRNA methylation (GO:0030488) | 2.90362513 |
81 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.89262683 |
82 | protein localization to kinetochore (GO:0034501) | 2.88618284 |
83 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.87467519 |
84 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.86375762 |
85 | DNA replication initiation (GO:0006270) | 2.86300334 |
86 | pteridine-containing compound metabolic process (GO:0042558) | 2.84887303 |
87 | protein complex disassembly (GO:0043241) | 2.83325452 |
88 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.83133962 |
89 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 2.83104505 |
90 | serine family amino acid catabolic process (GO:0009071) | 2.82324604 |
91 | negative regulation of RNA splicing (GO:0033119) | 2.82263331 |
92 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.82054875 |
93 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.82054875 |
94 | nuclear envelope disassembly (GO:0051081) | 2.81245576 |
95 | membrane disassembly (GO:0030397) | 2.81245576 |
96 | negative regulation of mRNA processing (GO:0050686) | 2.80502415 |
97 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.80022655 |
98 | rRNA processing (GO:0006364) | 2.79046427 |
99 | nuclear envelope reassembly (GO:0031468) | 2.78914023 |
100 | mitotic nuclear envelope reassembly (GO:0007084) | 2.78914023 |
101 | UTP biosynthetic process (GO:0006228) | 2.78871825 |
102 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.76939065 |
103 | L-phenylalanine catabolic process (GO:0006559) | 2.76939065 |
104 | negative regulation of cell size (GO:0045792) | 2.76338395 |
105 | pinocytosis (GO:0006907) | 2.74190537 |
106 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.71588423 |
107 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.70762973 |
108 | establishment of protein localization to mitochondrion (GO:0072655) | 2.70708805 |
109 | one-carbon metabolic process (GO:0006730) | 2.69299211 |
110 | peptidyl-arginine methylation (GO:0018216) | 2.69166028 |
111 | peptidyl-arginine N-methylation (GO:0035246) | 2.69166028 |
112 | rRNA metabolic process (GO:0016072) | 2.69163486 |
113 | macromolecular complex disassembly (GO:0032984) | 2.69142845 |
114 | IMP biosynthetic process (GO:0006188) | 2.68239620 |
115 | positive regulation of nuclease activity (GO:0032075) | 2.67668808 |
116 | transcription from mitochondrial promoter (GO:0006390) | 2.66779401 |
117 | protein targeting to membrane (GO:0006612) | 2.64494958 |
118 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.63830702 |
119 | translation (GO:0006412) | 2.63488965 |
120 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.63108328 |
121 | ATP synthesis coupled proton transport (GO:0015986) | 2.63108328 |
122 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.62437409 |
123 | negative regulation of ligase activity (GO:0051352) | 2.62437409 |
124 | T cell apoptotic process (GO:0070231) | 2.62131855 |
125 | pyrimidine-containing compound salvage (GO:0008655) | 2.62127220 |
126 | pyrimidine nucleoside salvage (GO:0043097) | 2.62127220 |
127 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.60921852 |
128 | protein complex localization (GO:0031503) | 2.60856700 |
129 | mRNA catabolic process (GO:0006402) | 2.60741149 |
130 | proteasome assembly (GO:0043248) | 2.60213456 |
131 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.59030521 |
132 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.58855301 |
133 | regulation of translational elongation (GO:0006448) | 2.58086667 |
134 | regulation of chromatin binding (GO:0035561) | 2.58047850 |
135 | apoptotic process involved in morphogenesis (GO:0060561) | 2.57651473 |
136 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.57143215 |
137 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.56707615 |
138 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.55883201 |
139 | spliceosomal snRNP assembly (GO:0000387) | 2.54518254 |
140 | pseudouridine synthesis (GO:0001522) | 2.53153915 |
141 | telomere maintenance via recombination (GO:0000722) | 2.52625781 |
142 | modulation by symbiont of host cellular process (GO:0044068) | 2.52128175 |
143 | glucose catabolic process (GO:0006007) | 2.51646564 |
144 | RNA catabolic process (GO:0006401) | 2.51250514 |
145 | folic acid transport (GO:0015884) | 2.50154561 |
146 | regulation of nuclease activity (GO:0032069) | 2.49975254 |
147 | negative regulation of mRNA metabolic process (GO:1903312) | 2.48674453 |
148 | negative regulation of fibrinolysis (GO:0051918) | 2.48167417 |
149 | regulation of protein heterodimerization activity (GO:0043497) | 2.48059836 |
150 | CTP metabolic process (GO:0046036) | 2.47514542 |
151 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.44398809 |
152 | lysine metabolic process (GO:0006553) | 2.43026684 |
153 | lysine catabolic process (GO:0006554) | 2.43026684 |
154 | proline biosynthetic process (GO:0006561) | 2.42420069 |
155 | tRNA aminoacylation for protein translation (GO:0006418) | 2.42215078 |
156 | protein maturation by protein folding (GO:0022417) | 2.42179267 |
157 | protein localization to chromosome, centromeric region (GO:0071459) | 2.41463073 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.30293998 |
2 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.11491645 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.35485814 |
4 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.60620286 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 2.56678519 |
6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.47227198 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.42482931 |
8 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.41098476 |
9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.31022300 |
10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.30953223 |
11 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.16568379 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.15825860 |
13 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.14357333 |
14 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.09472546 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06366073 |
16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.94845367 |
17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.94442753 |
18 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.88396966 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.82375637 |
20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.82034036 |
21 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.78834559 |
22 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.75687193 |
23 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.75432197 |
24 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.75339755 |
25 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.75199846 |
26 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.74111935 |
27 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73139874 |
28 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.70978869 |
29 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.68679073 |
30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.65982322 |
31 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.65103610 |
32 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.63817242 |
33 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.59165595 |
34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.55411849 |
35 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.50462867 |
36 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.48290449 |
37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.47856030 |
38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.47620618 |
39 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.47303658 |
40 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.45082665 |
41 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.41981357 |
42 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.40716847 |
43 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.39814950 |
44 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.39080601 |
45 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.38593713 |
46 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.38292424 |
47 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.38015914 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.37007945 |
49 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36807614 |
50 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.36383806 |
51 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.36378395 |
52 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.36275242 |
53 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.35297150 |
54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34231215 |
55 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.33470386 |
56 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.32799378 |
57 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31625619 |
58 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.30294080 |
59 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.29438330 |
60 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.28894882 |
61 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.27955560 |
62 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.23361194 |
63 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.21489094 |
64 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.19803925 |
65 | MAF_26560356_Chip-Seq_TH1_Human | 1.19491603 |
66 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.18599687 |
67 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.18372215 |
68 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.17364804 |
69 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.17230702 |
70 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.16232696 |
71 | UTX_26944678_Chip-Seq_JUKART_Human | 1.15787448 |
72 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.15486348 |
73 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.15459608 |
74 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15353029 |
75 | ATF3_27146783_Chip-Seq_COLON_Human | 1.13644455 |
76 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.12819682 |
77 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.12285467 |
78 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.11577509 |
79 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.11302844 |
80 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.10745632 |
81 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.10246111 |
82 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.09966915 |
83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09762354 |
84 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.09649322 |
85 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.08599878 |
86 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.08520463 |
87 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08484474 |
88 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.08018905 |
89 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.07647950 |
90 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.07568379 |
91 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.07449470 |
92 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06940481 |
93 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.05970204 |
94 | MAF_26560356_Chip-Seq_TH2_Human | 1.05287983 |
95 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.05234533 |
96 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.04420835 |
97 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.03377519 |
98 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.02836529 |
99 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02747065 |
100 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.02364216 |
101 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02113628 |
102 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.01981866 |
103 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.01924109 |
104 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.01921792 |
105 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.01418344 |
106 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.00999142 |
107 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.00445332 |
108 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.98774732 |
109 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.98692047 |
110 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.98257998 |
111 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98212489 |
112 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.98165663 |
113 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.98042835 |
114 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97935423 |
115 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97673306 |
116 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.97532506 |
117 | P68_20966046_ChIP-Seq_HELA_Human | 0.97348387 |
118 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.97120184 |
119 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.96593071 |
120 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.96521276 |
121 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.96202942 |
122 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.95905289 |
123 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.95840050 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.90711489 |
2 | MP0009840_abnormal_foam_cell | 3.42433079 |
3 | MP0005451_abnormal_body_composition | 3.36180787 |
4 | MP0002139_abnormal_hepatobiliary_system | 3.29555991 |
5 | MP0005360_urolithiasis | 3.28934320 |
6 | MP0004957_abnormal_blastocyst_morpholog | 3.03303748 |
7 | MP0003111_abnormal_nucleus_morphology | 2.93701764 |
8 | MP0003806_abnormal_nucleotide_metabolis | 2.65862155 |
9 | MP0010352_gastrointestinal_tract_polyps | 2.50000145 |
10 | MP0005365_abnormal_bile_salt | 2.47715140 |
11 | MP0005085_abnormal_gallbladder_physiolo | 2.38091818 |
12 | MP0003705_abnormal_hypodermis_morpholog | 2.28799075 |
13 | MP0003077_abnormal_cell_cycle | 2.22321230 |
14 | MP0000015_abnormal_ear_pigmentation | 2.19906519 |
15 | MP0003300_gastrointestinal_ulcer | 2.03554253 |
16 | MP0003646_muscle_fatigue | 2.03237895 |
17 | MP0005058_abnormal_lysosome_morphology | 2.02156308 |
18 | MP0000372_irregular_coat_pigmentation | 2.01913606 |
19 | MP0004185_abnormal_adipocyte_glucose | 2.00484850 |
20 | MP0001730_embryonic_growth_arrest | 1.97592022 |
21 | MP0000678_abnormal_parathyroid_gland | 1.97571778 |
22 | MP0005075_abnormal_melanosome_morpholog | 1.96112500 |
23 | MP0004381_abnormal_hair_follicle | 1.89225121 |
24 | MP0009333_abnormal_splenocyte_physiolog | 1.89190916 |
25 | MP0003191_abnormal_cellular_cholesterol | 1.82324158 |
26 | MP0010094_abnormal_chromosome_stability | 1.78969207 |
27 | MP0003303_peritoneal_inflammation | 1.77352184 |
28 | MP0002396_abnormal_hematopoietic_system | 1.76670410 |
29 | MP0008007_abnormal_cellular_replicative | 1.67727081 |
30 | MP0008260_abnormal_autophagy | 1.64626468 |
31 | MP0004233_abnormal_muscle_weight | 1.63989576 |
32 | MP0009379_abnormal_foot_pigmentation | 1.57789928 |
33 | MP0003786_premature_aging | 1.57159095 |
34 | MP0010307_abnormal_tumor_latency | 1.54923897 |
35 | MP0005220_abnormal_exocrine_pancreas | 1.54605564 |
36 | MP0000609_abnormal_liver_physiology | 1.53402305 |
37 | MP0001661_extended_life_span | 1.50683873 |
38 | MP0003763_abnormal_thymus_physiology | 1.49575568 |
39 | MP0000490_abnormal_crypts_of | 1.49222714 |
40 | MP0005083_abnormal_biliary_tract | 1.49159596 |
41 | MP0000350_abnormal_cell_proliferation | 1.49141353 |
42 | MP0005076_abnormal_cell_differentiation | 1.48782070 |
43 | MP0003252_abnormal_bile_duct | 1.48232076 |
44 | MP0002138_abnormal_hepatobiliary_system | 1.47951481 |
45 | MP0005501_abnormal_skin_physiology | 1.47496827 |
46 | MP0008875_abnormal_xenobiotic_pharmacok | 1.41131743 |
47 | MP0002080_prenatal_lethality | 1.40078408 |
48 | MP0010329_abnormal_lipoprotein_level | 1.39166142 |
49 | MP0000598_abnormal_liver_morphology | 1.37531102 |
50 | MP0000685_abnormal_immune_system | 1.37175020 |
51 | MP0003436_decreased_susceptibility_to | 1.36721036 |
52 | MP0003656_abnormal_erythrocyte_physiolo | 1.36363279 |
53 | MP0002796_impaired_skin_barrier | 1.35498085 |
54 | MP0002163_abnormal_gland_morphology | 1.29524402 |
55 | MP0001697_abnormal_embryo_size | 1.28070189 |
56 | MP0006035_abnormal_mitochondrial_morpho | 1.26276604 |
57 | MP0002019_abnormal_tumor_incidence | 1.24827680 |
58 | MP0002722_abnormal_immune_system | 1.24763288 |
59 | MP0001666_abnormal_nutrient_absorption | 1.24742059 |
60 | MP0001672_abnormal_embryogenesis/_devel | 1.23303159 |
61 | MP0005380_embryogenesis_phenotype | 1.23303159 |
62 | MP0005397_hematopoietic_system_phenotyp | 1.23224918 |
63 | MP0001545_abnormal_hematopoietic_system | 1.23224918 |
64 | MP0005332_abnormal_amino_acid | 1.23034993 |
65 | MP0002088_abnormal_embryonic_growth/wei | 1.22827358 |
66 | MP0003984_embryonic_growth_retardation | 1.22087686 |
67 | MP0009643_abnormal_urine_homeostasis | 1.21997094 |
68 | MP0005408_hypopigmentation | 1.21403572 |
69 | MP0003186_abnormal_redox_activity | 1.19810974 |
70 | MP0002089_abnormal_postnatal_growth/wei | 1.19432545 |
71 | MP0002398_abnormal_bone_marrow | 1.18826615 |
72 | MP0005319_abnormal_enzyme/_coenzyme | 1.18394120 |
73 | MP0003172_abnormal_lysosome_physiology | 1.18331524 |
74 | MP0000689_abnormal_spleen_morphology | 1.16730677 |
75 | MP0009672_abnormal_birth_weight | 1.15506910 |
76 | MP0000313_abnormal_cell_death | 1.15089732 |
77 | MP0000703_abnormal_thymus_morphology | 1.14333554 |
78 | MP0004808_abnormal_hematopoietic_stem | 1.12879147 |
79 | MP0003453_abnormal_keratinocyte_physiol | 1.12842360 |
80 | MP0005023_abnormal_wound_healing | 1.11706923 |
81 | MP0000358_abnormal_cell_content/ | 1.11516064 |
82 | MP0002086_abnormal_extraembryonic_tissu | 1.11202153 |
83 | MP0001853_heart_inflammation | 1.09240022 |
84 | MP0008932_abnormal_embryonic_tissue | 1.08383970 |
85 | MP0005330_cardiomyopathy | 1.07187772 |
86 | MP0000858_altered_metastatic_potential | 1.06975958 |
87 | MP0002249_abnormal_larynx_morphology | 1.06843432 |
88 | MP0001849_ear_inflammation | 1.06339407 |
89 | MP0002075_abnormal_coat/hair_pigmentati | 1.05026904 |
90 | MP0003566_abnormal_cell_adhesion | 1.04465839 |
91 | MP0008058_abnormal_DNA_repair | 1.03996030 |
92 | MP0005666_abnormal_adipose_tissue | 1.03994823 |
93 | MP0003866_abnormal_defecation | 1.01936856 |
94 | MP0009278_abnormal_bone_marrow | 1.01875640 |
95 | MP0005464_abnormal_platelet_physiology | 1.01810806 |
96 | MP0003221_abnormal_cardiomyocyte_apopto | 1.01638062 |
97 | MP0002429_abnormal_blood_cell | 1.01361960 |
98 | MP0001186_pigmentation_phenotype | 1.00426977 |
99 | MP0006036_abnormal_mitochondrial_physio | 0.99909424 |
100 | MP0000371_diluted_coat_color | 0.99458274 |
101 | MP0000343_altered_response_to | 0.98864666 |
102 | MP0000733_abnormal_muscle_development | 0.97133317 |
103 | MP0004858_abnormal_nervous_system | 0.95903728 |
104 | MP0000759_abnormal_skeletal_muscle | 0.95872532 |
105 | MP0001881_abnormal_mammary_gland | 0.95613166 |
106 | MP0003123_paternal_imprinting | 0.95553756 |
107 | MP0009053_abnormal_anal_canal | 0.95132511 |
108 | MP0002132_abnormal_respiratory_system | 0.94631719 |
109 | MP0003119_abnormal_digestive_system | 0.94433519 |
110 | MP0002653_abnormal_ependyma_morphology | 0.93265426 |
111 | MP0005623_abnormal_meninges_morphology | 0.93224457 |
112 | MP0002085_abnormal_embryonic_tissue | 0.91542584 |
113 | MP0001944_abnormal_pancreas_morphology | 0.90351559 |
114 | MP0004197_abnormal_fetal_growth/weight/ | 0.90070730 |
115 | MP0005670_abnormal_white_adipose | 0.89914026 |
116 | MP0000750_abnormal_muscle_regeneration | 0.89582719 |
117 | MP0000716_abnormal_immune_system | 0.88697046 |
118 | MP0000003_abnormal_adipose_tissue | 0.88670343 |
119 | MP0001727_abnormal_embryo_implantation | 0.87666717 |
120 | MP0000477_abnormal_intestine_morphology | 0.87119484 |
121 | MP0005375_adipose_tissue_phenotype | 0.85878266 |
122 | MP0002084_abnormal_developmental_patter | 0.84275168 |
123 | MP0003136_yellow_coat_color | 0.84031650 |
124 | MP0005257_abnormal_intraocular_pressure | 0.83429541 |
125 | MP0002269_muscular_atrophy | 0.82728557 |
126 | MP0005621_abnormal_cell_physiology | 0.82085685 |
127 | MP0000604_amyloidosis | 0.81263489 |
128 | MP0002405_respiratory_system_inflammati | 0.80792572 |
129 | MP0001348_abnormal_lacrimal_gland | 0.80474710 |
130 | MP0001800_abnormal_humoral_immune | 0.79981561 |
131 | MP0000747_muscle_weakness | 0.79915922 |
132 | MP0002092_abnormal_eye_morphology | 0.78818615 |
133 | MP0008469_abnormal_protein_level | 0.78295419 |
134 | MP0006054_spinal_hemorrhage | 0.78118619 |
135 | MP0005384_cellular_phenotype | 0.77022555 |
136 | MP0010155_abnormal_intestine_physiology | 0.75954509 |
137 | MP0004947_skin_inflammation | 0.75013552 |
138 | MP0005636_abnormal_mineral_homeostasis | 0.75012745 |
139 | MP0004087_abnormal_muscle_fiber | 0.74753633 |
140 | MP0010030_abnormal_orbit_morphology | 0.74439943 |
141 | MP0002693_abnormal_pancreas_physiology | 0.73861985 |
142 | MP0008961_abnormal_basal_metabolism | 0.73812344 |
143 | MP0001845_abnormal_inflammatory_respons | 0.73750178 |
144 | MP0002877_abnormal_melanocyte_morpholog | 0.72863414 |
145 | MP0009931_abnormal_skin_appearance | 0.72792767 |
146 | MP0002060_abnormal_skin_morphology | 0.72225831 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Microvesicular hepatic steatosis (HP:0001414) | 4.77720070 |
2 | Testicular atrophy (HP:0000029) | 4.10489349 |
3 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 4.03523895 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.64199024 |
5 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.43017812 |
6 | Progressive muscle weakness (HP:0003323) | 3.10293112 |
7 | Overriding aorta (HP:0002623) | 3.08771582 |
8 | Hypobetalipoproteinemia (HP:0003563) | 3.01378044 |
9 | Microretrognathia (HP:0000308) | 2.93507963 |
10 | Elfin facies (HP:0004428) | 2.92488864 |
11 | Xanthomatosis (HP:0000991) | 2.90508912 |
12 | Renovascular hypertension (HP:0100817) | 2.89923079 |
13 | Deep venous thrombosis (HP:0002625) | 2.88448819 |
14 | Multiple enchondromatosis (HP:0005701) | 2.88260818 |
15 | Gout (HP:0001997) | 2.86670407 |
16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.85104551 |
17 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.82753776 |
18 | Abnormality of glycolysis (HP:0004366) | 2.82116886 |
19 | Progressive external ophthalmoplegia (HP:0000590) | 2.81901366 |
20 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.79506106 |
21 | Hyperglycinemia (HP:0002154) | 2.67130015 |
22 | Thrombocytosis (HP:0001894) | 2.64639675 |
23 | Spastic diplegia (HP:0001264) | 2.64556590 |
24 | Abnormality of the Achilles tendon (HP:0005109) | 2.64450338 |
25 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.63379392 |
26 | Abnormal number of erythroid precursors (HP:0012131) | 2.63242606 |
27 | Renal duplication (HP:0000075) | 2.59180775 |
28 | Generalized amyotrophy (HP:0003700) | 2.56093638 |
29 | Increased serum pyruvate (HP:0003542) | 2.53517301 |
30 | Broad distal phalanx of finger (HP:0009836) | 2.53378426 |
31 | Late onset (HP:0003584) | 2.47863310 |
32 | Achilles tendon contracture (HP:0001771) | 2.47277157 |
33 | Reticulocytopenia (HP:0001896) | 2.47006561 |
34 | Abnormality of the umbilical cord (HP:0010881) | 2.44196313 |
35 | Hand muscle atrophy (HP:0009130) | 2.42931640 |
36 | Aplastic anemia (HP:0001915) | 2.42163974 |
37 | Abnormality of reticulocytes (HP:0004312) | 2.40420253 |
38 | Severe visual impairment (HP:0001141) | 2.40160890 |
39 | Hypoglycemic coma (HP:0001325) | 2.38582617 |
40 | Macrocytic anemia (HP:0001972) | 2.37651116 |
41 | Increased connective tissue (HP:0009025) | 2.36890481 |
42 | Reticulocytosis (HP:0001923) | 2.36715455 |
43 | Acute necrotizing encephalopathy (HP:0006965) | 2.35978967 |
44 | 3-Methylglutaconic aciduria (HP:0003535) | 2.33629840 |
45 | Abnormal neuron morphology (HP:0012757) | 2.33199350 |
46 | Abnormality of the motor neurons (HP:0002450) | 2.33199350 |
47 | Sensory axonal neuropathy (HP:0003390) | 2.32471623 |
48 | Hypergonadotropic hypogonadism (HP:0000815) | 2.30249781 |
49 | Selective tooth agenesis (HP:0001592) | 2.29300247 |
50 | Protrusio acetabuli (HP:0003179) | 2.27609838 |
51 | Abnormality of the lower motor neuron (HP:0002366) | 2.25884328 |
52 | Increased intramyocellular lipid droplets (HP:0012240) | 2.23727001 |
53 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.23309060 |
54 | Hypokinesia (HP:0002375) | 2.22654954 |
55 | Hyperammonemia (HP:0001987) | 2.22111999 |
56 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.21558760 |
57 | Increased muscle lipid content (HP:0009058) | 2.21440236 |
58 | Degeneration of anterior horn cells (HP:0002398) | 2.19932715 |
59 | Abnormality of the anterior horn cell (HP:0006802) | 2.19932715 |
60 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.18414962 |
61 | Single umbilical artery (HP:0001195) | 2.18414962 |
62 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.18414962 |
63 | Intrahepatic cholestasis (HP:0001406) | 2.18393726 |
64 | Rough bone trabeculation (HP:0100670) | 2.17492061 |
65 | Trismus (HP:0000211) | 2.17032442 |
66 | Paralysis (HP:0003470) | 2.16533783 |
67 | Orthostatic hypotension (HP:0001278) | 2.15986023 |
68 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.14672834 |
69 | Angiofibromas (HP:0010615) | 2.14492231 |
70 | Adenoma sebaceum (HP:0009720) | 2.14492231 |
71 | Abnormal gallbladder physiology (HP:0012438) | 2.14354682 |
72 | Cholecystitis (HP:0001082) | 2.14354682 |
73 | Cerebral hypomyelination (HP:0006808) | 2.13986909 |
74 | Exercise intolerance (HP:0003546) | 2.13716820 |
75 | Acute encephalopathy (HP:0006846) | 2.12589747 |
76 | Oral leukoplakia (HP:0002745) | 2.09917047 |
77 | Abnormality of the common coagulation pathway (HP:0010990) | 2.09909463 |
78 | Ketosis (HP:0001946) | 2.09327541 |
79 | Ulnar bowing (HP:0003031) | 2.08826670 |
80 | Breast hypoplasia (HP:0003187) | 2.07705699 |
81 | Global brain atrophy (HP:0002283) | 2.06445867 |
82 | Distal upper limb amyotrophy (HP:0007149) | 2.06219106 |
83 | Upper limb amyotrophy (HP:0009129) | 2.06219106 |
84 | Distal lower limb amyotrophy (HP:0008944) | 2.05984792 |
85 | Pallor (HP:0000980) | 2.05087888 |
86 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.04874133 |
87 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.04874133 |
88 | Personality changes (HP:0000751) | 2.03920780 |
89 | Ankle contracture (HP:0006466) | 2.03467387 |
90 | Abnormality of glycine metabolism (HP:0010895) | 2.02862031 |
91 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.02862031 |
92 | Abnormal cartilage morphology (HP:0002763) | 2.01749850 |
93 | Premature skin wrinkling (HP:0100678) | 2.00619623 |
94 | Dysphonia (HP:0001618) | 2.00461856 |
95 | Nonimmune hydrops fetalis (HP:0001790) | 1.99774020 |
96 | Ependymoma (HP:0002888) | 1.98313429 |
97 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.97809233 |
98 | Megaloblastic anemia (HP:0001889) | 1.97761150 |
99 | Nasal polyposis (HP:0100582) | 1.97400496 |
100 | Increased serum ferritin (HP:0003281) | 1.96869995 |
101 | Carpal bone hypoplasia (HP:0001498) | 1.96668039 |
102 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.95726194 |
103 | Increased CSF lactate (HP:0002490) | 1.94656615 |
104 | Hypertensive crisis (HP:0100735) | 1.92372495 |
105 | Flat cornea (HP:0007720) | 1.91583848 |
106 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.91512077 |
107 | Abnormality of nucleobase metabolism (HP:0010932) | 1.90965402 |
108 | Abnormality of iron homeostasis (HP:0011031) | 1.89900444 |
109 | Distal lower limb muscle weakness (HP:0009053) | 1.89226692 |
110 | Hyperglycinuria (HP:0003108) | 1.88830160 |
111 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.88356786 |
112 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.88356786 |
113 | Micronodular cirrhosis (HP:0001413) | 1.86485912 |
114 | Ileus (HP:0002595) | 1.85077574 |
115 | Amyotrophic lateral sclerosis (HP:0007354) | 1.84697819 |
116 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.83974891 |
117 | Secondary amenorrhea (HP:0000869) | 1.83618766 |
118 | Impaired proprioception (HP:0010831) | 1.83610987 |
119 | Hyperacusis (HP:0010780) | 1.83025737 |
120 | Mitochondrial inheritance (HP:0001427) | 1.82977777 |
121 | Increased serum lactate (HP:0002151) | 1.82069508 |
122 | Progressive hearing impairment (HP:0001730) | 1.81592025 |
123 | Elbow flexion contracture (HP:0002987) | 1.81376435 |
124 | 11 pairs of ribs (HP:0000878) | 1.80580844 |
125 | Septate vagina (HP:0001153) | 1.80340366 |
126 | Delayed CNS myelination (HP:0002188) | 1.79257948 |
127 | Ragged-red muscle fibers (HP:0003200) | 1.79109659 |
128 | Vertebral compression fractures (HP:0002953) | 1.79020211 |
129 | Neoplasm of the pancreas (HP:0002894) | 1.78981880 |
130 | Neonatal onset (HP:0003623) | 1.78944789 |
131 | IgM deficiency (HP:0002850) | 1.77844320 |
132 | Increased nuchal translucency (HP:0010880) | 1.77322599 |
133 | Gastrointestinal dysmotility (HP:0002579) | 1.77162295 |
134 | Pelvic girdle muscle weakness (HP:0003749) | 1.76831675 |
135 | Impaired platelet aggregation (HP:0003540) | 1.76222598 |
136 | Abnormal platelet function (HP:0011869) | 1.76222598 |
137 | Premature ovarian failure (HP:0008209) | 1.75543911 |
138 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.75524563 |
139 | Abnormality of the nasal mucosa (HP:0000433) | 1.74075289 |
140 | Abnormality of the intrinsic pathway (HP:0010989) | 1.73108445 |
141 | Hypolipoproteinemia (HP:0010981) | 1.71622709 |
142 | Birth length less than 3rd percentile (HP:0003561) | 1.71351164 |
143 | Polycythemia (HP:0001901) | 1.71103953 |
144 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.70927392 |
145 | Insulin resistance (HP:0000855) | 1.70412495 |
146 | Irritability (HP:0000737) | 1.70370706 |
147 | Axonal loss (HP:0003447) | 1.69482469 |
148 | Patellar dislocation (HP:0002999) | 1.69358975 |
149 | Cerebral aneurysm (HP:0004944) | 1.69182180 |
150 | Abnormal trabecular bone morphology (HP:0100671) | 1.69121793 |
151 | Increased variability in muscle fiber diameter (HP:0003557) | 1.68699821 |
152 | Entropion (HP:0000621) | 1.68592204 |
153 | Myopathic facies (HP:0002058) | 1.67600208 |
154 | Cleft eyelid (HP:0000625) | 1.67273590 |
155 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.65992396 |
156 | Limb hypertonia (HP:0002509) | 1.65933200 |
157 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.65615433 |
158 | Abnormality of T cell physiology (HP:0011840) | 1.65568612 |
159 | Insomnia (HP:0100785) | 1.62092854 |
160 | Slender long bone (HP:0003100) | 1.61219499 |
161 | Sparse eyelashes (HP:0000653) | 1.61006884 |
162 | Squamous cell carcinoma (HP:0002860) | 1.60825053 |
163 | Ocular albinism (HP:0001107) | 1.60156716 |
164 | Hyperbilirubinemia (HP:0002904) | 1.59946766 |
165 | Prolonged partial thromboplastin time (HP:0003645) | 1.59442621 |
166 | Petechiae (HP:0000967) | 1.59087743 |
167 | Colon cancer (HP:0003003) | 1.58763265 |
168 | Increased density of long bones (HP:0006392) | 1.58613272 |
169 | Cerebral edema (HP:0002181) | 1.58567250 |
170 | Dysautonomia (HP:0002459) | 1.58487357 |
171 | Albinism (HP:0001022) | 1.56522723 |
172 | Respiratory difficulties (HP:0002880) | 1.55887420 |
173 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.55641493 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.32201633 |
2 | SMG1 | 3.36037610 |
3 | ERN1 | 3.19766884 |
4 | TESK2 | 3.07876465 |
5 | PKN2 | 2.99675311 |
6 | TRIB3 | 2.78634992 |
7 | VRK2 | 2.71526864 |
8 | MAP3K10 | 2.58736954 |
9 | IRAK3 | 2.55799195 |
10 | CDK8 | 2.54005838 |
11 | NME2 | 2.48311315 |
12 | SCYL2 | 2.34951565 |
13 | WEE1 | 2.34555280 |
14 | EEF2K | 2.32094998 |
15 | DYRK3 | 2.27597074 |
16 | EIF2AK1 | 2.26864026 |
17 | FLT3 | 2.08599137 |
18 | MAP4K1 | 2.00173276 |
19 | ICK | 1.93190545 |
20 | NEK2 | 1.92432383 |
21 | BCKDK | 1.90129799 |
22 | PASK | 1.84506639 |
23 | TESK1 | 1.83633390 |
24 | RPS6KA4 | 1.81902724 |
25 | EPHA2 | 1.77978370 |
26 | KDR | 1.65532489 |
27 | MAP3K11 | 1.62603929 |
28 | TSSK6 | 1.55581945 |
29 | MAP3K8 | 1.55220300 |
30 | CDC42BPA | 1.53048102 |
31 | GRK6 | 1.49492197 |
32 | PRPF4B | 1.48508707 |
33 | NEK1 | 1.45881340 |
34 | RPS6KB2 | 1.42743721 |
35 | FGFR4 | 1.42193241 |
36 | RIPK1 | 1.34989143 |
37 | PAK4 | 1.34680904 |
38 | LRRK2 | 1.30604995 |
39 | PIM2 | 1.28037010 |
40 | CLK1 | 1.26317281 |
41 | ZAP70 | 1.25837587 |
42 | IRAK4 | 1.17835875 |
43 | CDK4 | 1.14010304 |
44 | TLK1 | 1.13411797 |
45 | STK10 | 1.09722912 |
46 | TTK | 1.03871526 |
47 | AURKA | 1.00536879 |
48 | CDC7 | 0.99098154 |
49 | TYK2 | 0.98659033 |
50 | PTK6 | 0.96019041 |
51 | BRSK2 | 0.94109957 |
52 | MAP2K2 | 0.92866999 |
53 | SIK1 | 0.92009600 |
54 | TBK1 | 0.91819197 |
55 | PLK1 | 0.89765760 |
56 | PBK | 0.88184256 |
57 | EIF2AK3 | 0.86119735 |
58 | BRSK1 | 0.84958821 |
59 | MAP2K3 | 0.84763391 |
60 | ALK | 0.84312164 |
61 | LMTK2 | 0.83059907 |
62 | PLK4 | 0.82633856 |
63 | MAPKAPK3 | 0.81424012 |
64 | CDK7 | 0.79079563 |
65 | MST1R | 0.77634832 |
66 | PRKD2 | 0.77340720 |
67 | AURKB | 0.77217440 |
68 | MELK | 0.70028608 |
69 | BTK | 0.68887240 |
70 | STK4 | 0.68790018 |
71 | PAK1 | 0.67691858 |
72 | VRK1 | 0.67200047 |
73 | JAK3 | 0.66887164 |
74 | MAP3K3 | 0.66848994 |
75 | MST4 | 0.65480737 |
76 | LIMK1 | 0.65146221 |
77 | MTOR | 0.64023103 |
78 | SRPK1 | 0.63398533 |
79 | MAPKAPK2 | 0.62162460 |
80 | ACVR1B | 0.61134522 |
81 | TAOK1 | 0.60849243 |
82 | PIM1 | 0.58084410 |
83 | PAK2 | 0.57656247 |
84 | MUSK | 0.57041704 |
85 | PTK2 | 0.55291380 |
86 | ILK | 0.54846820 |
87 | HIPK2 | 0.54676410 |
88 | BRAF | 0.54454227 |
89 | AKT2 | 0.54377699 |
90 | MAPK11 | 0.54262298 |
91 | PRKCI | 0.52833261 |
92 | PRKG2 | 0.49892311 |
93 | ABL2 | 0.49625666 |
94 | ATR | 0.48483725 |
95 | MAP3K1 | 0.48251191 |
96 | DAPK1 | 0.48142805 |
97 | DAPK3 | 0.47572457 |
98 | KSR2 | 0.47387197 |
99 | DYRK1B | 0.46564130 |
100 | PDPK1 | 0.45271140 |
101 | CHEK1 | 0.44988425 |
102 | TAOK2 | 0.44229643 |
103 | NME1 | 0.44090111 |
104 | TGFBR1 | 0.41379284 |
105 | CSF1R | 0.41002750 |
106 | CDK9 | 0.38442632 |
107 | CDK2 | 0.37936885 |
108 | CHEK2 | 0.37654410 |
109 | RAF1 | 0.37455279 |
110 | STK16 | 0.35757168 |
111 | CSNK2A2 | 0.35261890 |
112 | TTN | 0.35120415 |
113 | CSNK2A1 | 0.34185868 |
114 | PDGFRA | 0.32678125 |
115 | CDK11A | 0.32436426 |
116 | ARAF | 0.31984031 |
117 | RPS6KA1 | 0.31741578 |
118 | SIK2 | 0.31467090 |
119 | IRAK2 | 0.31395637 |
120 | JAK2 | 0.30145457 |
121 | CDK1 | 0.27674672 |
122 | RPS6KA5 | 0.27106147 |
123 | CDK6 | 0.26600775 |
124 | BLK | 0.26474072 |
125 | LATS2 | 0.25769118 |
126 | CDK12 | 0.25442286 |
127 | CSK | 0.25436225 |
128 | CDK15 | 0.25346516 |
129 | RPS6KL1 | 0.24108556 |
130 | RPS6KC1 | 0.24108556 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.18429647 |
2 | Ribosome_Homo sapiens_hsa03010 | 2.96444336 |
3 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.63402332 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.54631618 |
5 | Proteasome_Homo sapiens_hsa03050 | 2.54095166 |
6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.32255428 |
7 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.27939178 |
8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.27138590 |
9 | Spliceosome_Homo sapiens_hsa03040 | 2.15804508 |
10 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.13652765 |
11 | Mismatch repair_Homo sapiens_hsa03430 | 2.12550000 |
12 | RNA transport_Homo sapiens_hsa03013 | 2.09156628 |
13 | Sulfur relay system_Homo sapiens_hsa04122 | 2.08502420 |
14 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.07907601 |
15 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 2.06228675 |
16 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.05350997 |
17 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 2.03560694 |
18 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.02985179 |
19 | RNA polymerase_Homo sapiens_hsa03020 | 1.96851379 |
20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.95064669 |
21 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.90434572 |
22 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.82321149 |
23 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.76833463 |
24 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.75991353 |
25 | Base excision repair_Homo sapiens_hsa03410 | 1.75154154 |
26 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.61327059 |
27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.57828574 |
28 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.52678354 |
29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.48887407 |
30 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.47985951 |
31 | Carbon metabolism_Homo sapiens_hsa01200 | 1.45476955 |
32 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.37360863 |
33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.36871771 |
34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.36674306 |
35 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.33693811 |
36 | Cell cycle_Homo sapiens_hsa04110 | 1.33456941 |
37 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20810056 |
38 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.17706299 |
39 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.15342034 |
40 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.12844193 |
41 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.10742802 |
42 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.07776820 |
43 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.06423447 |
44 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.06392226 |
45 | Protein export_Homo sapiens_hsa03060 | 1.03243903 |
46 | Galactose metabolism_Homo sapiens_hsa00052 | 1.00598895 |
47 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.97282996 |
48 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.96928731 |
49 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.95224675 |
50 | Bladder cancer_Homo sapiens_hsa05219 | 0.95041610 |
51 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.93168369 |
52 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.91214128 |
53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.89619594 |
54 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.85328206 |
55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.83727444 |
56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83720753 |
57 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.83040568 |
58 | Alzheimers disease_Homo sapiens_hsa05010 | 0.82497022 |
59 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.81220221 |
60 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.78407616 |
61 | Homologous recombination_Homo sapiens_hsa03440 | 0.78398425 |
62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.77545424 |
63 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.75535029 |
64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70710843 |
65 | Thyroid cancer_Homo sapiens_hsa05216 | 0.70588510 |
66 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.70123647 |
67 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.68812430 |
68 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67082845 |
69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.66282173 |
70 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.64929515 |
71 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.64163813 |
72 | Legionellosis_Homo sapiens_hsa05134 | 0.63156088 |
73 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.62763921 |
74 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62497196 |
75 | Shigellosis_Homo sapiens_hsa05131 | 0.61348696 |
76 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.60304209 |
77 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.60132076 |
78 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.58348439 |
79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58327175 |
80 | RNA degradation_Homo sapiens_hsa03018 | 0.56779386 |
81 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.56731669 |
82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.55530431 |
83 | HTLV-I infection_Homo sapiens_hsa05166 | 0.54903843 |
84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54900900 |
85 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.54163548 |
86 | Apoptosis_Homo sapiens_hsa04210 | 0.54065201 |
87 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.53739093 |
88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53042660 |
89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52210126 |
90 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.51227415 |
91 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50953877 |
92 | Purine metabolism_Homo sapiens_hsa00230 | 0.50744136 |
93 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49733845 |
94 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.49036612 |
95 | Peroxisome_Homo sapiens_hsa04146 | 0.48702957 |
96 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.47228330 |
97 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.47049333 |
98 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.42192387 |
99 | Bile secretion_Homo sapiens_hsa04976 | 0.40879281 |
100 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.40274642 |
101 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.40173663 |
102 | Prion diseases_Homo sapiens_hsa05020 | 0.39374624 |
103 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.39204194 |
104 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.38925254 |
105 | Other glycan degradation_Homo sapiens_hsa00511 | 0.38885101 |
106 | Basal transcription factors_Homo sapiens_hsa03022 | 0.35146470 |
107 | Histidine metabolism_Homo sapiens_hsa00340 | 0.34677044 |
108 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34103929 |
109 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.33792134 |
110 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.32693606 |
111 | Viral myocarditis_Homo sapiens_hsa05416 | 0.31960834 |
112 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.30403737 |
113 | Metabolic pathways_Homo sapiens_hsa01100 | 0.27713752 |
114 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.26873975 |
115 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.26734972 |
116 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.26519639 |
117 | Lysosome_Homo sapiens_hsa04142 | 0.26447072 |
118 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.26053862 |
119 | Insulin resistance_Homo sapiens_hsa04931 | 0.25443187 |
120 | Melanoma_Homo sapiens_hsa05218 | 0.24965350 |
121 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.23552456 |
122 | Measles_Homo sapiens_hsa05162 | 0.22913171 |
123 | Hepatitis B_Homo sapiens_hsa05161 | 0.22786068 |
124 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.22754887 |
125 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.22550550 |
126 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.20893695 |
127 | Alcoholism_Homo sapiens_hsa05034 | 0.20312598 |
128 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.20034517 |