

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.64472869 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.64472869 |
| 3 | purine deoxyribonucleotide catabolic process (GO:0009155) | 6.60376602 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.54142271 |
| 5 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 6.02309915 |
| 6 | deoxyribonucleotide catabolic process (GO:0009264) | 5.37825349 |
| 7 | deoxyribose phosphate catabolic process (GO:0046386) | 5.16792668 |
| 8 | respiratory electron transport chain (GO:0022904) | 5.15471982 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 5.12902799 |
| 10 | electron transport chain (GO:0022900) | 5.01739368 |
| 11 | actin nucleation (GO:0045010) | 4.99047275 |
| 12 | proteasome assembly (GO:0043248) | 4.85278220 |
| 13 | ribosomal small subunit biogenesis (GO:0042274) | 4.76546963 |
| 14 | DNA deamination (GO:0045006) | 4.67569544 |
| 15 | maturation of SSU-rRNA (GO:0030490) | 4.64085325 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.61748430 |
| 17 | autophagic vacuole fusion (GO:0000046) | 4.38702583 |
| 18 | purine nucleotide salvage (GO:0032261) | 4.25662837 |
| 19 | viral transcription (GO:0019083) | 4.08131244 |
| 20 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.99620266 |
| 21 | NADH dehydrogenase complex assembly (GO:0010257) | 3.99620266 |
| 22 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.99620266 |
| 23 | translational termination (GO:0006415) | 3.92962160 |
| 24 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.89917502 |
| 25 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.84287158 |
| 26 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.78707068 |
| 27 | sequestering of actin monomers (GO:0042989) | 3.69585869 |
| 28 | cotranslational protein targeting to membrane (GO:0006613) | 3.69120454 |
| 29 | ATP biosynthetic process (GO:0006754) | 3.62299824 |
| 30 | protein targeting to ER (GO:0045047) | 3.62041122 |
| 31 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.60567344 |
| 32 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.58642454 |
| 33 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.55456739 |
| 34 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.47337234 |
| 35 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.46645923 |
| 36 | protein localization to endoplasmic reticulum (GO:0070972) | 3.45082324 |
| 37 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.44581656 |
| 38 | protein complex biogenesis (GO:0070271) | 3.41169120 |
| 39 | reactive oxygen species biosynthetic process (GO:1903409) | 3.39803428 |
| 40 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.38325626 |
| 41 | regulation of RIG-I signaling pathway (GO:0039535) | 3.37981165 |
| 42 | translational elongation (GO:0006414) | 3.36055487 |
| 43 | hydrogen ion transmembrane transport (GO:1902600) | 3.32641576 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.32073870 |
| 45 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.25572662 |
| 46 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.24262705 |
| 47 | deoxyribose phosphate metabolic process (GO:0019692) | 3.24234717 |
| 48 | positive regulation of lamellipodium assembly (GO:0010592) | 3.24047839 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.22730890 |
| 50 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.20515344 |
| 51 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.20287682 |
| 52 | chaperone-mediated protein transport (GO:0072321) | 3.19845046 |
| 53 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.19158762 |
| 54 | oxidative phosphorylation (GO:0006119) | 3.18838538 |
| 55 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.18597987 |
| 56 | organelle membrane fusion (GO:0090174) | 3.16622454 |
| 57 | nucleoside diphosphate catabolic process (GO:0009134) | 3.15987945 |
| 58 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.15571322 |
| 59 | response to interferon-beta (GO:0035456) | 3.13742140 |
| 60 | energy homeostasis (GO:0097009) | 3.10523589 |
| 61 | positive regulation of growth hormone secretion (GO:0060124) | 3.10343251 |
| 62 | aerobic respiration (GO:0009060) | 3.08612384 |
| 63 | cytidine deamination (GO:0009972) | 3.03866061 |
| 64 | cytidine metabolic process (GO:0046087) | 3.03866061 |
| 65 | cytidine catabolic process (GO:0006216) | 3.03866061 |
| 66 | negative regulation of telomere maintenance (GO:0032205) | 3.02649599 |
| 67 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.01738715 |
| 68 | secretory granule organization (GO:0033363) | 3.00247435 |
| 69 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.98786786 |
| 70 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.98786786 |
| 71 | pseudouridine synthesis (GO:0001522) | 2.97808246 |
| 72 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.97443807 |
| 73 | cellular protein complex disassembly (GO:0043624) | 2.96860995 |
| 74 | translational initiation (GO:0006413) | 2.96105133 |
| 75 | viral life cycle (GO:0019058) | 2.95970307 |
| 76 | positive regulation of heart rate (GO:0010460) | 2.95693919 |
| 77 | proton transport (GO:0015992) | 2.95196247 |
| 78 | negative regulation of phagocytosis (GO:0050765) | 2.92852635 |
| 79 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.92757284 |
| 80 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.92757284 |
| 81 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.92457682 |
| 82 | regulation of protein heterodimerization activity (GO:0043497) | 2.91888193 |
| 83 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 2.90619020 |
| 84 | platelet dense granule organization (GO:0060155) | 2.89878663 |
| 85 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.89637727 |
| 86 | translation (GO:0006412) | 2.89476458 |
| 87 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.89409527 |
| 88 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.89409527 |
| 89 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.89409527 |
| 90 | negative regulation of DNA biosynthetic process (GO:2000279) | 2.89202148 |
| 91 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.89096198 |
| 92 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.88545785 |
| 93 | hydrogen transport (GO:0006818) | 2.88177087 |
| 94 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.86873016 |
| 95 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.86642994 |
| 96 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.84323662 |
| 97 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.83554982 |
| 98 | negative regulation of ligase activity (GO:0051352) | 2.82393239 |
| 99 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.82393239 |
| 100 | deoxyribonucleotide metabolic process (GO:0009262) | 2.81966451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 5.26632223 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.67489141 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.12894544 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.94062515 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.92131781 |
| 6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.42294920 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.35397336 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.27899253 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.27869912 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.20433789 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.93022929 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.88192326 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.76226888 |
| 14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.47433260 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.42378612 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.41932782 |
| 17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.40525838 |
| 18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.38875141 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.30396887 |
| 20 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.29793840 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.28888004 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.27029771 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.17689532 |
| 24 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.16304792 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.12817124 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.08810266 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.05071621 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.97964619 |
| 29 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.87378652 |
| 30 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.85183187 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.84692768 |
| 32 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.84678359 |
| 33 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81721762 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.74815281 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.73251364 |
| 36 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.72460788 |
| 37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.69549121 |
| 38 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.69477314 |
| 39 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.68144535 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.64733854 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.60919551 |
| 42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.60456929 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.58908837 |
| 44 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.57264604 |
| 45 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.56793427 |
| 46 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.55032879 |
| 47 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.49911719 |
| 48 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.48998927 |
| 49 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.47760729 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.38330249 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37696591 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.36350756 |
| 53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.36207878 |
| 54 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33978230 |
| 55 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.29955032 |
| 56 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.22495689 |
| 57 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19811098 |
| 58 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.19055444 |
| 59 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.13843445 |
| 60 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.13659250 |
| 61 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.13569554 |
| 62 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.10035701 |
| 63 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09991388 |
| 64 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.08741241 |
| 65 | MYB_26560356_Chip-Seq_TH2_Human | 1.08711603 |
| 66 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.08530972 |
| 67 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.08349808 |
| 68 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.07049199 |
| 69 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.04995893 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.04961644 |
| 71 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.04205027 |
| 72 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.01758682 |
| 73 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.01061426 |
| 74 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.99809208 |
| 75 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98467415 |
| 76 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.97721085 |
| 77 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.94013773 |
| 78 | GATA3_26560356_Chip-Seq_TH2_Human | 0.93257009 |
| 79 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.92523435 |
| 80 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.91278456 |
| 81 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.90194248 |
| 82 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90081729 |
| 83 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90045882 |
| 84 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.88889328 |
| 85 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.87714420 |
| 86 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.85317629 |
| 87 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.84740943 |
| 88 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.84306630 |
| 89 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.84277473 |
| 90 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.83655132 |
| 91 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.83404716 |
| 92 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.83291453 |
| 93 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.81622428 |
| 94 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.81490870 |
| 95 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.81050961 |
| 96 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.79652451 |
| 97 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.79388038 |
| 98 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.77481350 |
| 99 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.77240066 |
| 100 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.75821140 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.61532191 |
| 2 | MP0005671_abnormal_response_to | 3.51769648 |
| 3 | MP0005670_abnormal_white_adipose | 3.17583104 |
| 4 | MP0009785_altered_susceptibility_to | 2.99067112 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.69665107 |
| 6 | MP0000015_abnormal_ear_pigmentation | 2.54824421 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.52436935 |
| 8 | MP0006036_abnormal_mitochondrial_physio | 2.41734719 |
| 9 | MP0008058_abnormal_DNA_repair | 2.33127367 |
| 10 | MP0003186_abnormal_redox_activity | 2.27859014 |
| 11 | MP0009764_decreased_sensitivity_to | 2.18146484 |
| 12 | MP0002095_abnormal_skin_pigmentation | 2.17081298 |
| 13 | MP0009697_abnormal_copulation | 2.05827112 |
| 14 | MP0001835_abnormal_antigen_presentation | 1.97895904 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 1.94640215 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 1.91422507 |
| 17 | MP0006292_abnormal_olfactory_placode | 1.83653663 |
| 18 | MP0002090_abnormal_vision | 1.78645381 |
| 19 | MP0002102_abnormal_ear_morphology | 1.73788039 |
| 20 | MP0005025_abnormal_response_to | 1.73365867 |
| 21 | MP0003315_abnormal_perineum_morphology | 1.66732380 |
| 22 | MP0003724_increased_susceptibility_to | 1.63404697 |
| 23 | MP0005319_abnormal_enzyme/_coenzyme | 1.63319656 |
| 24 | MP0001764_abnormal_homeostasis | 1.62607461 |
| 25 | MP0003786_premature_aging | 1.61538467 |
| 26 | MP0002132_abnormal_respiratory_system | 1.60601010 |
| 27 | MP0010094_abnormal_chromosome_stability | 1.56663644 |
| 28 | MP0005464_abnormal_platelet_physiology | 1.54883344 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.49777551 |
| 30 | MP0005000_abnormal_immune_tolerance | 1.49736983 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.44894049 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 1.44786885 |
| 33 | MP0004957_abnormal_blastocyst_morpholog | 1.42715253 |
| 34 | MP0008872_abnormal_physiological_respon | 1.38109948 |
| 35 | MP0005330_cardiomyopathy | 1.36665362 |
| 36 | MP0002148_abnormal_hypersensitivity_rea | 1.34384698 |
| 37 | MP0001800_abnormal_humoral_immune | 1.33810606 |
| 38 | MP0002420_abnormal_adaptive_immunity | 1.33461614 |
| 39 | MP0003718_maternal_effect | 1.31855428 |
| 40 | MP0005332_abnormal_amino_acid | 1.30742477 |
| 41 | MP0002723_abnormal_immune_serum | 1.30460209 |
| 42 | MP0002405_respiratory_system_inflammati | 1.27301194 |
| 43 | MP0001819_abnormal_immune_cell | 1.26587491 |
| 44 | MP0003252_abnormal_bile_duct | 1.26390421 |
| 45 | MP0003075_altered_response_to | 1.24161496 |
| 46 | MP0005266_abnormal_metabolism | 1.23135129 |
| 47 | MP0000685_abnormal_immune_system | 1.20075590 |
| 48 | MP0003646_muscle_fatigue | 1.19579168 |
| 49 | MP0002452_abnormal_antigen_presenting | 1.19526317 |
| 50 | MP0002166_altered_tumor_susceptibility | 1.19417646 |
| 51 | MP0002736_abnormal_nociception_after | 1.18882060 |
| 52 | MP0008469_abnormal_protein_level | 1.18415056 |
| 53 | MP0005376_homeostasis/metabolism_phenot | 1.16394116 |
| 54 | MP0005646_abnormal_pituitary_gland | 1.15388656 |
| 55 | MP0003787_abnormal_imprinting | 1.14395524 |
| 56 | MP0008873_increased_physiological_sensi | 1.11815699 |
| 57 | MP0002876_abnormal_thyroid_physiology | 1.10556355 |
| 58 | MP0001881_abnormal_mammary_gland | 1.08414386 |
| 59 | MP0002419_abnormal_innate_immunity | 1.04812807 |
| 60 | MP0003567_abnormal_fetal_cardiomyocyte | 1.00279063 |
| 61 | MP0001502_abnormal_circadian_rhythm | 0.99850189 |
| 62 | MP0004043_abnormal_pH_regulation | 0.99821914 |
| 63 | MP0005253_abnormal_eye_physiology | 0.99331725 |
| 64 | MP0001845_abnormal_inflammatory_respons | 0.98052175 |
| 65 | MP0000716_abnormal_immune_system | 0.96104586 |
| 66 | MP0004019_abnormal_vitamin_homeostasis | 0.94852206 |
| 67 | MP0002019_abnormal_tumor_incidence | 0.92124284 |
| 68 | MP0003763_abnormal_thymus_physiology | 0.92111679 |
| 69 | MP0006082_CNS_inflammation | 0.91747106 |
| 70 | MP0008932_abnormal_embryonic_tissue | 0.90246580 |
| 71 | MP0002398_abnormal_bone_marrow | 0.90141292 |
| 72 | MP0003959_abnormal_lean_body | 0.89243717 |
| 73 | MP0001661_extended_life_span | 0.88962081 |
| 74 | MP0001905_abnormal_dopamine_level | 0.87616007 |
| 75 | MP0005636_abnormal_mineral_homeostasis | 0.87424140 |
| 76 | MP0003806_abnormal_nucleotide_metabolis | 0.86192341 |
| 77 | MP0000313_abnormal_cell_death | 0.85491014 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.83775944 |
| 79 | MP0000689_abnormal_spleen_morphology | 0.83433373 |
| 80 | MP0001853_heart_inflammation | 0.80824074 |
| 81 | MP0002177_abnormal_outer_ear | 0.80796727 |
| 82 | MP0002429_abnormal_blood_cell | 0.80777877 |
| 83 | MP0003077_abnormal_cell_cycle | 0.80592883 |
| 84 | MP0001119_abnormal_female_reproductive | 0.79943477 |
| 85 | MP0009278_abnormal_bone_marrow | 0.79429523 |
| 86 | MP0002933_joint_inflammation | 0.78584485 |
| 87 | MP0005174_abnormal_tail_pigmentation | 0.77025032 |
| 88 | MP0002136_abnormal_kidney_physiology | 0.75891364 |
| 89 | MP0000230_abnormal_systemic_arterial | 0.74772211 |
| 90 | MP0001293_anophthalmia | 0.74193596 |
| 91 | MP0002722_abnormal_immune_system | 0.73870724 |
| 92 | MP0002006_tumorigenesis | 0.73832337 |
| 93 | MP0001756_abnormal_urination | 0.72593466 |
| 94 | MP0009763_increased_sensitivity_to | 0.71930528 |
| 95 | MP0001790_abnormal_immune_system | 0.71295012 |
| 96 | MP0005387_immune_system_phenotype | 0.71295012 |
| 97 | MP0000343_altered_response_to | 0.69766004 |
| 98 | MP0005075_abnormal_melanosome_morpholog | 0.69629655 |
| 99 | MP0001765_abnormal_ion_homeostasis | 0.65670473 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.65273213 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Lipid accumulation in hepatocytes (HP:0006561) | 5.33550267 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 5.17439128 |
| 3 | Increased intramyocellular lipid droplets (HP:0012240) | 4.73430979 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.72084167 |
| 5 | Increased muscle lipid content (HP:0009058) | 4.71726154 |
| 6 | Renal Fanconi syndrome (HP:0001994) | 4.56568224 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 4.45101246 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.30913296 |
| 9 | Increased CSF lactate (HP:0002490) | 4.09889768 |
| 10 | Hepatocellular necrosis (HP:0001404) | 4.01680843 |
| 11 | Aplastic anemia (HP:0001915) | 3.94268712 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.91556602 |
| 13 | Hepatic necrosis (HP:0002605) | 3.76235573 |
| 14 | Sensory axonal neuropathy (HP:0003390) | 3.68087031 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.61510944 |
| 16 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.57858268 |
| 17 | Exertional dyspnea (HP:0002875) | 3.50310966 |
| 18 | Acute encephalopathy (HP:0006846) | 3.40349318 |
| 19 | Reticulocytopenia (HP:0001896) | 3.32578454 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 3.28346905 |
| 21 | Respiratory difficulties (HP:0002880) | 3.18410894 |
| 22 | Obstructive lung disease (HP:0006536) | 3.12560416 |
| 23 | Chronic obstructive pulmonary disease (HP:0006510) | 3.12560416 |
| 24 | Cerebral edema (HP:0002181) | 3.10572672 |
| 25 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.06662752 |
| 26 | Abnormality of the tricuspid valve (HP:0001702) | 3.00586292 |
| 27 | Abnormality of renal resorption (HP:0011038) | 2.98503153 |
| 28 | Increased serum lactate (HP:0002151) | 2.97787010 |
| 29 | Abnormality of B cell number (HP:0010975) | 2.94400533 |
| 30 | B lymphocytopenia (HP:0010976) | 2.90325925 |
| 31 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.89002217 |
| 32 | Lactic acidosis (HP:0003128) | 2.86614305 |
| 33 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.73924292 |
| 34 | Thrombocytosis (HP:0001894) | 2.71370063 |
| 35 | Macrocytic anemia (HP:0001972) | 2.67332649 |
| 36 | Hyperphosphaturia (HP:0003109) | 2.62579148 |
| 37 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.58012481 |
| 38 | Stenosis of the external auditory canal (HP:0000402) | 2.55595742 |
| 39 | Exercise intolerance (HP:0003546) | 2.54291662 |
| 40 | Generalized aminoaciduria (HP:0002909) | 2.53696158 |
| 41 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.49710914 |
| 42 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49430195 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.46695666 |
| 44 | Respiratory failure (HP:0002878) | 2.44725267 |
| 45 | Spastic paraparesis (HP:0002313) | 2.44147132 |
| 46 | Short middle phalanx of the 5th finger (HP:0004220) | 2.41100790 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.40934290 |
| 48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.40934290 |
| 49 | Acute hepatic failure (HP:0006554) | 2.37946824 |
| 50 | Partial duplication of thumb phalanx (HP:0009944) | 2.37104935 |
| 51 | Glycosuria (HP:0003076) | 2.34369463 |
| 52 | Abnormality of urine glucose concentration (HP:0011016) | 2.34369463 |
| 53 | Autoimmune hemolytic anemia (HP:0001890) | 2.33332817 |
| 54 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.33164916 |
| 55 | Leukodystrophy (HP:0002415) | 2.30600634 |
| 56 | 11 pairs of ribs (HP:0000878) | 2.30475750 |
| 57 | Hypoplasia of the radius (HP:0002984) | 2.27120559 |
| 58 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.26395961 |
| 59 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.20523056 |
| 60 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.17650217 |
| 61 | Short 1st metacarpal (HP:0010034) | 2.17650217 |
| 62 | Birth length less than 3rd percentile (HP:0003561) | 2.17609438 |
| 63 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.15937694 |
| 64 | Dicarboxylic aciduria (HP:0003215) | 2.15937694 |
| 65 | Pancytopenia (HP:0001876) | 2.13658012 |
| 66 | Mesangial abnormality (HP:0001966) | 2.08479032 |
| 67 | Partial duplication of the phalanx of hand (HP:0009999) | 2.07910655 |
| 68 | Hyperthyroidism (HP:0000836) | 2.07507334 |
| 69 | Pallor (HP:0000980) | 2.07443495 |
| 70 | Cellular immunodeficiency (HP:0005374) | 2.07124899 |
| 71 | Renal cortical cysts (HP:0000803) | 2.05978198 |
| 72 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.04457225 |
| 73 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.03566539 |
| 74 | Hypoplastic left heart (HP:0004383) | 2.01108422 |
| 75 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.97687905 |
| 76 | Symptomatic seizures (HP:0011145) | 1.96740081 |
| 77 | Constricted visual fields (HP:0001133) | 1.95568902 |
| 78 | Autoimmune thrombocytopenia (HP:0001973) | 1.95441705 |
| 79 | Severe combined immunodeficiency (HP:0004430) | 1.94888383 |
| 80 | Abnormality of the 1st metacarpal (HP:0010009) | 1.91860571 |
| 81 | Absent thumb (HP:0009777) | 1.91369789 |
| 82 | Spontaneous hematomas (HP:0007420) | 1.88368402 |
| 83 | Myotonia (HP:0002486) | 1.87830532 |
| 84 | Abnormal number of erythroid precursors (HP:0012131) | 1.87639203 |
| 85 | Synostosis of carpal bones (HP:0005048) | 1.87037865 |
| 86 | Oral leukoplakia (HP:0002745) | 1.86151487 |
| 87 | Abnormal urine phosphate concentration (HP:0012599) | 1.84830895 |
| 88 | Cleft eyelid (HP:0000625) | 1.83498695 |
| 89 | Congenital, generalized hypertrichosis (HP:0004540) | 1.81533883 |
| 90 | Testicular atrophy (HP:0000029) | 1.79629637 |
| 91 | Unilateral renal agenesis (HP:0000122) | 1.79273621 |
| 92 | Optic disc pallor (HP:0000543) | 1.79187998 |
| 93 | Prostate neoplasm (HP:0100787) | 1.78689464 |
| 94 | Recurrent abscess formation (HP:0002722) | 1.76875364 |
| 95 | Tetany (HP:0001281) | 1.76609224 |
| 96 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.74980375 |
| 97 | Colon cancer (HP:0003003) | 1.74239962 |
| 98 | Increased cerebral lipofuscin (HP:0011813) | 1.71815893 |
| 99 | Missing ribs (HP:0000921) | 1.69781766 |
| 100 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.69411082 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCYL2 | 4.98190650 |
| 2 | BCKDK | 4.27172665 |
| 3 | TESK2 | 4.08236403 |
| 4 | KDR | 3.69430875 |
| 5 | CDC7 | 3.34653134 |
| 6 | MAP3K12 | 3.03949193 |
| 7 | DAPK1 | 2.70316005 |
| 8 | NUAK1 | 2.63846980 |
| 9 | TESK1 | 2.61618835 |
| 10 | BMPR2 | 2.48780120 |
| 11 | NME2 | 2.37205285 |
| 12 | VRK2 | 2.32679999 |
| 13 | RPS6KA4 | 2.22015915 |
| 14 | CDK19 | 2.15447570 |
| 15 | MAPKAPK3 | 2.05381187 |
| 16 | LIMK1 | 2.03896475 |
| 17 | WNK4 | 1.96433043 |
| 18 | MYLK | 1.96023318 |
| 19 | TAOK3 | 1.94581443 |
| 20 | PBK | 1.40855135 |
| 21 | MAP3K6 | 1.37914413 |
| 22 | GRK6 | 1.32415374 |
| 23 | ILK | 1.15378307 |
| 24 | CSNK1G3 | 1.13370532 |
| 25 | MAP2K7 | 1.11193293 |
| 26 | OXSR1 | 1.00008918 |
| 27 | STK16 | 0.97549542 |
| 28 | VRK1 | 0.94012768 |
| 29 | AURKA | 0.88747764 |
| 30 | ATR | 0.86923522 |
| 31 | PDK2 | 0.86156938 |
| 32 | MAP4K2 | 0.83355836 |
| 33 | GRK1 | 0.83309782 |
| 34 | RPS6KA5 | 0.80110072 |
| 35 | TXK | 0.79119885 |
| 36 | STK39 | 0.78806398 |
| 37 | DAPK3 | 0.76142992 |
| 38 | CAMK1 | 0.75799343 |
| 39 | TRPM7 | 0.75537489 |
| 40 | ERN1 | 0.75474732 |
| 41 | CSNK1A1L | 0.72581931 |
| 42 | BMX | 0.71877337 |
| 43 | KIT | 0.68503792 |
| 44 | MAP4K1 | 0.67783784 |
| 45 | CLK1 | 0.67572471 |
| 46 | PAK1 | 0.66372123 |
| 47 | DMPK | 0.65742652 |
| 48 | CSNK1G1 | 0.65349816 |
| 49 | CSNK1G2 | 0.64895201 |
| 50 | PNCK | 0.64038726 |
| 51 | ADRBK2 | 0.60622058 |
| 52 | CAMKK2 | 0.60253363 |
| 53 | TBK1 | 0.60001110 |
| 54 | ABL2 | 0.59137109 |
| 55 | DYRK2 | 0.59079324 |
| 56 | CDK3 | 0.57565613 |
| 57 | FLT3 | 0.57071957 |
| 58 | RAF1 | 0.55452933 |
| 59 | MAPKAPK5 | 0.55367769 |
| 60 | CDK7 | 0.54993780 |
| 61 | ARAF | 0.54702048 |
| 62 | CAMK1G | 0.54254235 |
| 63 | CSNK2A1 | 0.53778368 |
| 64 | PIK3CA | 0.53063464 |
| 65 | IKBKE | 0.51698171 |
| 66 | MOS | 0.50897132 |
| 67 | ZAK | 0.50782379 |
| 68 | CSNK2A2 | 0.48517642 |
| 69 | MINK1 | 0.47797696 |
| 70 | SYK | 0.47268325 |
| 71 | CSF1R | 0.47143079 |
| 72 | TEC | 0.47111669 |
| 73 | EIF2AK3 | 0.46111501 |
| 74 | ITK | 0.45843358 |
| 75 | PLK1 | 0.45016608 |
| 76 | STK4 | 0.43265072 |
| 77 | INSRR | 0.41932211 |
| 78 | MKNK1 | 0.41488071 |
| 79 | CDK9 | 0.41056621 |
| 80 | CAMK2G | 0.41047204 |
| 81 | TAOK2 | 0.39456056 |
| 82 | MAP3K4 | 0.38818808 |
| 83 | LYN | 0.37780207 |
| 84 | IKBKB | 0.37360321 |
| 85 | MAP3K5 | 0.37174235 |
| 86 | GRK5 | 0.36875835 |
| 87 | MAPK13 | 0.35221948 |
| 88 | ROCK1 | 0.35157532 |
| 89 | CDK11A | 0.34561561 |
| 90 | MKNK2 | 0.32187886 |
| 91 | CDK8 | 0.31906853 |
| 92 | WNK3 | 0.31101834 |
| 93 | ZAP70 | 0.30959648 |
| 94 | PRKCQ | 0.30097333 |
| 95 | BUB1 | 0.29789678 |
| 96 | MAPKAPK2 | 0.29285501 |
| 97 | BTK | 0.28748841 |
| 98 | MAP3K11 | 0.28705565 |
| 99 | AURKB | 0.28561767 |
| 100 | CDK14 | 0.28489274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.84227578 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.21843321 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.18982908 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.92178648 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.07935925 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.81374795 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.69069405 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.60747224 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.49132121 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.14975668 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.04444556 |
| 12 | Protein export_Homo sapiens_hsa03060 | 1.98706027 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.96271623 |
| 14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.74052171 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.71885789 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.68901392 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.68535966 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.63546854 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.60235390 |
| 20 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.53903815 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.50972065 |
| 22 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.48898249 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.48800985 |
| 24 | RNA polymerase_Homo sapiens_hsa03020 | 1.44883075 |
| 25 | Sulfur relay system_Homo sapiens_hsa04122 | 1.39598988 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.37894911 |
| 27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.34553143 |
| 28 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.29402289 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.26818046 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25421842 |
| 31 | Base excision repair_Homo sapiens_hsa03410 | 1.22985654 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.19812910 |
| 33 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.19535838 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.17033643 |
| 35 | Allograft rejection_Homo sapiens_hsa05330 | 1.11059682 |
| 36 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.10521101 |
| 37 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.09159883 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.02681392 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.00638018 |
| 40 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.00487988 |
| 41 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.00484209 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.93036403 |
| 43 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.91656624 |
| 44 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.89559060 |
| 45 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.88166530 |
| 46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84100161 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.81981413 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.81157519 |
| 49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81150405 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80043405 |
| 51 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.78771723 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.77799503 |
| 53 | Salmonella infection_Homo sapiens_hsa05132 | 0.73508753 |
| 54 | RNA transport_Homo sapiens_hsa03013 | 0.73219744 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.72746430 |
| 56 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.72516036 |
| 57 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71971121 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.71962928 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70669897 |
| 60 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.70485656 |
| 61 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.67095741 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.66270862 |
| 63 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.65995412 |
| 64 | Viral myocarditis_Homo sapiens_hsa05416 | 0.63675476 |
| 65 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.63331940 |
| 66 | Basal transcription factors_Homo sapiens_hsa03022 | 0.63210569 |
| 67 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.62671142 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60291728 |
| 69 | Pertussis_Homo sapiens_hsa05133 | 0.57968723 |
| 70 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.55735448 |
| 71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52389907 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49110575 |
| 73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.48759723 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47877146 |
| 75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46419186 |
| 76 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.44869490 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44810087 |
| 78 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.42550380 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41414757 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.40813129 |
| 81 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.38731684 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38693132 |
| 83 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37011186 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.35881293 |
| 85 | Shigellosis_Homo sapiens_hsa05131 | 0.34318348 |
| 86 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34087721 |
| 87 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33388725 |
| 88 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.32687810 |
| 89 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.32635243 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32271126 |
| 91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.31840675 |
| 92 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30601661 |
| 93 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.29248198 |
| 94 | Leishmaniasis_Homo sapiens_hsa05140 | 0.26579212 |
| 95 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.26404493 |
| 96 | Carbon metabolism_Homo sapiens_hsa01200 | 0.23402574 |
| 97 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.21525237 |
| 98 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.20940643 |
| 99 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.20392823 |
| 100 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.20238697 |

