FAM213A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1alpha-linolenic acid metabolic process (GO:0036109)5.07279585
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.40975091
3L-phenylalanine catabolic process (GO:0006559)4.40975091
4cysteine metabolic process (GO:0006534)4.40377830
5triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.33734704
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.22253530
7L-phenylalanine metabolic process (GO:0006558)4.22253530
8short-chain fatty acid metabolic process (GO:0046459)4.15168187
9fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.99359634
10lysine metabolic process (GO:0006553)3.90983510
11lysine catabolic process (GO:0006554)3.90983510
12fatty acid beta-oxidation (GO:0006635)3.89646471
13sulfur amino acid catabolic process (GO:0000098)3.83606450
14glutamate metabolic process (GO:0006536)3.78984802
15positive regulation of fatty acid beta-oxidation (GO:0032000)3.74061285
16lipid oxidation (GO:0034440)3.70640780
17fatty acid oxidation (GO:0019395)3.68963934
18positive regulation of fatty acid oxidation (GO:0046321)3.68018874
19valine metabolic process (GO:0006573)3.68017821
20biotin metabolic process (GO:0006768)3.65079813
21aromatic amino acid family catabolic process (GO:0009074)3.56585522
22low-density lipoprotein particle clearance (GO:0034383)3.55540527
23regulation of triglyceride catabolic process (GO:0010896)3.53172250
24fatty acid catabolic process (GO:0009062)3.52922565
25amino-acid betaine metabolic process (GO:0006577)3.51903865
26succinate metabolic process (GO:0006105)3.50676486
27fatty acid homeostasis (GO:0055089)3.43807019
28acetyl-CoA metabolic process (GO:0006084)3.37633281
29branched-chain amino acid catabolic process (GO:0009083)3.35183267
30triglyceride catabolic process (GO:0019433)3.35083329
31monocarboxylic acid catabolic process (GO:0072329)3.35048326
32neutral lipid catabolic process (GO:0046461)3.34835166
33acylglycerol catabolic process (GO:0046464)3.34835166
34acyl-CoA biosynthetic process (GO:0071616)3.33729479
35thioester biosynthetic process (GO:0035384)3.33729479
36aspartate family amino acid catabolic process (GO:0009068)3.32741894
37very long-chain fatty acid metabolic process (GO:0000038)3.31173675
38dicarboxylic acid catabolic process (GO:0043649)3.29949061
39branched-chain amino acid metabolic process (GO:0009081)3.27756617
40glyoxylate metabolic process (GO:0046487)3.24121817
41fatty-acyl-CoA biosynthetic process (GO:0046949)3.24119821
42cellular modified amino acid catabolic process (GO:0042219)3.23604654
43carnitine metabolic process (GO:0009437)3.23143089
44bile acid biosynthetic process (GO:0006699)3.22341365
45regulation of sequestering of triglyceride (GO:0010889)3.22047798
46cellular ketone body metabolic process (GO:0046950)3.21388104
47reverse cholesterol transport (GO:0043691)3.21372633
48positive regulation of lipid catabolic process (GO:0050996)3.20655173
49cellular amino acid catabolic process (GO:0009063)3.17899023
50regulation of cholesterol homeostasis (GO:2000188)3.17234049
51pyrimidine nucleobase catabolic process (GO:0006208)3.16820629
52regulation of fatty acid beta-oxidation (GO:0031998)3.14795910
53tricarboxylic acid metabolic process (GO:0072350)3.13003943
54triglyceride biosynthetic process (GO:0019432)3.11589351
55purine nucleotide transport (GO:0015865)3.11485170
56long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.10604921
57regulation of fatty acid oxidation (GO:0046320)3.09531798
58ethanol oxidation (GO:0006069)3.09199383
59regulation of cholesterol biosynthetic process (GO:0045540)3.08749568
60alpha-amino acid catabolic process (GO:1901606)3.08177934
612-oxoglutarate metabolic process (GO:0006103)3.08135517
62regulation of cholesterol esterification (GO:0010872)3.08042168
63regulation of bile acid biosynthetic process (GO:0070857)3.08003798
64neutral lipid biosynthetic process (GO:0046460)3.07794823
65acylglycerol biosynthetic process (GO:0046463)3.07794823
66presynaptic membrane assembly (GO:0097105)3.05997461
67fructose metabolic process (GO:0006000)3.03662556
68carboxylic acid catabolic process (GO:0046395)3.03588466
69organic acid catabolic process (GO:0016054)3.03588466
70high-density lipoprotein particle remodeling (GO:0034375)3.03030779
71hormone catabolic process (GO:0042447)3.01958399
72protein-lipid complex remodeling (GO:0034368)3.01845928
73macromolecular complex remodeling (GO:0034367)3.01845928
74plasma lipoprotein particle remodeling (GO:0034369)3.01845928
75very-low-density lipoprotein particle assembly (GO:0034379)3.00647762
76dicarboxylic acid biosynthetic process (GO:0043650)3.00184358
77tryptophan catabolic process (GO:0006569)2.99787536
78indole-containing compound catabolic process (GO:0042436)2.99787536
79indolalkylamine catabolic process (GO:0046218)2.99787536
80fatty-acyl-CoA metabolic process (GO:0035337)2.99074882
81flavonoid metabolic process (GO:0009812)2.99062758
82regulation of cholesterol metabolic process (GO:0090181)2.97062500
83adenine nucleotide transport (GO:0051503)2.95891967
84presynaptic membrane organization (GO:0097090)2.94147780
85linoleic acid metabolic process (GO:0043651)2.93431555
86positive regulation of fatty acid metabolic process (GO:0045923)2.92447374
87triglyceride metabolic process (GO:0006641)2.91762102
88triglyceride homeostasis (GO:0070328)2.90056865
89acylglycerol homeostasis (GO:0055090)2.90056865
90L-amino acid import (GO:0043092)2.88198940
91fatty acid transmembrane transport (GO:1902001)2.88080266
92acyl-CoA metabolic process (GO:0006637)2.86676886
93thioester metabolic process (GO:0035383)2.86676886
94alanine transport (GO:0032328)2.86279608
95lipid particle organization (GO:0034389)2.86273209
96postsynaptic membrane organization (GO:0001941)2.85810407
97neurotransmitter-gated ion channel clustering (GO:0072578)2.83853414
98plasma lipoprotein particle clearance (GO:0034381)2.83740932
99tryptophan metabolic process (GO:0006568)2.83238674
100positive regulation of triglyceride metabolic process (GO:0090208)2.82475104
101phospholipid homeostasis (GO:0055091)2.81472285
102C4-dicarboxylate transport (GO:0015740)2.80948233
103homocysteine metabolic process (GO:0050667)2.80928407
104low-density lipoprotein particle remodeling (GO:0034374)2.80604615
105response to methylmercury (GO:0051597)2.80221382
106response to dietary excess (GO:0002021)2.80070599
107glycerolipid catabolic process (GO:0046503)2.79749164
108diacylglycerol metabolic process (GO:0046339)2.79177474
109kynurenine metabolic process (GO:0070189)2.79161466
110serine family amino acid catabolic process (GO:0009071)2.79010737
111nucleobase catabolic process (GO:0046113)2.78530365
112complement activation, alternative pathway (GO:0006957)2.78497764
113coenzyme catabolic process (GO:0009109)2.77185573
114axonal fasciculation (GO:0007413)2.73005759
115CDP-diacylglycerol biosynthetic process (GO:0016024)2.69440008
116membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.66060275
117dendritic spine morphogenesis (GO:0060997)2.63027998
118central nervous system myelination (GO:0022010)2.59502341
119axon ensheathment in central nervous system (GO:0032291)2.59502341
120brown fat cell differentiation (GO:0050873)2.59451350
121regulation of glycogen (starch) synthase activity (GO:2000465)2.57952933
122neuron recognition (GO:0008038)2.54398209
123vocalization behavior (GO:0071625)2.53303415
124negative regulation of cytosolic calcium ion concentration (GO:0051481)2.46520615
125cholesterol biosynthetic process (GO:0006695)2.45505739
126glycerol metabolic process (GO:0006071)2.44005890
127long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.43116850
128retinol metabolic process (GO:0042572)2.42815568
129CDP-diacylglycerol metabolic process (GO:0046341)2.41359602
130L-serine transport (GO:0015825)2.40287301
131response to phenylpropanoid (GO:0080184)2.38759010
132auditory behavior (GO:0031223)2.35095595
133embryonic retina morphogenesis in camera-type eye (GO:0060059)2.34489374
134sterol biosynthetic process (GO:0016126)2.33284640
135positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.32692802
136synaptic vesicle maturation (GO:0016188)2.32111322
137white fat cell differentiation (GO:0050872)2.31895648
138primary alcohol metabolic process (GO:0034308)2.30868623
139transmission of nerve impulse (GO:0019226)2.29370001
140negative regulation of lipase activity (GO:0060192)2.27215071
141neuron cell-cell adhesion (GO:0007158)2.25913560
142neurotransmitter catabolic process (GO:0042135)2.25462956
143detection of calcium ion (GO:0005513)2.24038996
144response to nitrosative stress (GO:0051409)2.22107268
145peroxisome fission (GO:0016559)2.21452316
146positive regulation of glycolytic process (GO:0045821)2.20712835
147neuronal action potential propagation (GO:0019227)2.17726308
148neuronal ion channel clustering (GO:0045161)2.17099422
149behavioral response to nicotine (GO:0035095)2.16937482
150regulation of synapse structural plasticity (GO:0051823)2.16494094
151short-term memory (GO:0007614)2.14696951
152cGMP-mediated signaling (GO:0019934)2.12588627
153regulation of cAMP-dependent protein kinase activity (GO:2000479)2.12579730
154alditol metabolic process (GO:0019400)2.12180357
155water-soluble vitamin biosynthetic process (GO:0042364)2.10614023
156synaptic vesicle docking involved in exocytosis (GO:0016081)2.09751466
157fatty acid elongation (GO:0030497)2.06936326
158glutamate secretion (GO:0014047)2.06717258
159regulation of short-term neuronal synaptic plasticity (GO:0048172)2.04293539
160cellular potassium ion homeostasis (GO:0030007)2.03757203
161response to auditory stimulus (GO:0010996)2.03235901
162cochlea development (GO:0090102)2.02778225
163retinal ganglion cell axon guidance (GO:0031290)2.02449263
164nonmotile primary cilium assembly (GO:0035058)2.01066360

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.63772216
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.63286863
3RXR_22158963_ChIP-Seq_LIVER_Mouse4.08784989
4LXR_22158963_ChIP-Seq_LIVER_Mouse3.42414804
5PPARA_22158963_ChIP-Seq_LIVER_Mouse3.31101605
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.84031187
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.73036327
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.66197177
9TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27912620
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.26828174
11NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.18709712
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.03020524
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86815311
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.84337883
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.81524545
16CBX2_27304074_Chip-Seq_ESCs_Mouse1.80937807
17EZH2_22144423_ChIP-Seq_EOC_Human1.80543979
18IGF1R_20145208_ChIP-Seq_DFB_Human1.80368922
19GBX2_23144817_ChIP-Seq_PC3_Human1.79390497
20CLOCK_20551151_ChIP-Seq_293T_Human1.66685671
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.62810514
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.61830836
23MTF2_20144788_ChIP-Seq_MESCs_Mouse1.61697240
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.60906482
25ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.59880707
26ERG_21242973_ChIP-ChIP_JURKAT_Human1.58871484
27PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.58353839
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56228315
29SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.55673772
30EZH2_18974828_ChIP-Seq_MESCs_Mouse1.55318195
31RNF2_18974828_ChIP-Seq_MESCs_Mouse1.55318195
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.53762274
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.47727808
34PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.47530454
35JARID2_20064375_ChIP-Seq_MESCs_Mouse1.46736024
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.46256985
37SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.45245823
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.44735164
39SMAD3_21741376_ChIP-Seq_EPCs_Human1.44378320
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.43179611
41GATA1_22025678_ChIP-Seq_K562_Human1.41958737
42DROSHA_22980978_ChIP-Seq_HELA_Human1.40392701
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39392022
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39371226
45RNF2_27304074_Chip-Seq_NSC_Mouse1.36086302
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.32885455
47AR_21572438_ChIP-Seq_LNCaP_Human1.32625536
48VDR_22108803_ChIP-Seq_LS180_Human1.31070429
49ESR1_20079471_ChIP-ChIP_T-47D_Human1.30442394
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.30134861
51FOXA2_19822575_ChIP-Seq_HepG2_Human1.29219020
52ZNF274_21170338_ChIP-Seq_K562_Hela1.28247535
53FUS_26573619_Chip-Seq_HEK293_Human1.27935905
54BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25497188
55BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23120066
56TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.22922680
57TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22332236
58MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21892945
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.20342175
60EZH2_27294783_Chip-Seq_ESCs_Mouse1.19783996
61SUZ12_27294783_Chip-Seq_ESCs_Mouse1.15540500
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14737545
63KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14198287
64MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.13451128
65BCAT_22108803_ChIP-Seq_LS180_Human1.13392335
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.12272706
67REST_21632747_ChIP-Seq_MESCs_Mouse1.11450744
68ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10368262
69STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09540561
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08876417
71ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07930909
72GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.07401926
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07241198
74RXR_22108803_ChIP-Seq_LS180_Human1.06228482
75AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.06164036
76RNF2_27304074_Chip-Seq_ESCs_Mouse1.04420870
77UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03900140
78EZH2_27304074_Chip-Seq_ESCs_Mouse1.03334837
79SMAD4_21799915_ChIP-Seq_A2780_Human1.01842277
80NANOG_18555785_Chip-Seq_ESCs_Mouse1.01174304
81RARB_27405468_Chip-Seq_BRAIN_Mouse1.00724045
82FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00499811
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00002521
84TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00002521
85CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99835257
86TRIM28_21343339_ChIP-Seq_HEK293_Human0.99709548
87AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99192568
88TCF4_22108803_ChIP-Seq_LS180_Human0.99179359
89RUNX2_22187159_ChIP-Seq_PCA_Human0.98349657
90MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98317148
91TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.97945862
92PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97611554
93NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96603522
94LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96348184
95SMAD3_21741376_ChIP-Seq_HESCs_Human0.95927172
96REST_18959480_ChIP-ChIP_MESCs_Mouse0.95850542
97TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95827623
98THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95783966
99NR3C1_23031785_ChIP-Seq_PC12_Mouse0.94555869
100TCF4_23295773_ChIP-Seq_U87_Human0.94159422
101GATA1_19941826_ChIP-Seq_K562_Human0.94010199
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93342168
103P300_19829295_ChIP-Seq_ESCs_Human0.93148057
104NRF2_20460467_ChIP-Seq_MEFs_Mouse0.93138519
105NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.93138519
106CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92641507
107RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.92073123
108PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.91915032
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90251760
110YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90007104
111MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89876063
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88785602
113RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88671003
114* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.88542277
115AR_25329375_ChIP-Seq_VCAP_Human0.87909910
116KLF5_20875108_ChIP-Seq_MESCs_Mouse0.87411933
117SOX2_21211035_ChIP-Seq_LN229_Gbm0.87290425
118CBP_20019798_ChIP-Seq_JUKART_Human0.87133599
119SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86976051
120HNF4A_19822575_ChIP-Seq_HepG2_Human0.83080740
121RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82500242
122PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.82353904
123IKZF1_21737484_ChIP-ChIP_HCT116_Human0.81842753
124HTT_18923047_ChIP-ChIP_STHdh_Human0.80778489
125EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.80737462
126STAT3_23295773_ChIP-Seq_U87_Human0.78877193
127SMAD4_21741376_ChIP-Seq_HESCs_Human0.78870141
128SOX2_27498859_Chip-Seq_STOMACH_Mouse0.78773133
129AR_19668381_ChIP-Seq_PC3_Human0.78659615
130GATA2_19941826_ChIP-Seq_K562_Human0.77685758
131TAF15_26573619_Chip-Seq_HEK293_Human0.76239874
132SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76053642
133OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.75967387
134AUTS2_25519132_ChIP-Seq_293T-REX_Human0.75804554
135EP300_21415370_ChIP-Seq_HL-1_Mouse0.75451705
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.74531928
137TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.74172340
138HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.73985399
139SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.72959480
140TOP2B_26459242_ChIP-Seq_MCF-7_Human0.72441443
141RING1B_27294783_Chip-Seq_ESCs_Mouse0.71844878
142ARNT_22903824_ChIP-Seq_MCF-7_Human0.71331187

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.52072517
2MP0005360_urolithiasis4.74169309
3MP0005365_abnormal_bile_salt4.10915720
4MP0005085_abnormal_gallbladder_physiolo3.51329798
5MP0010329_abnormal_lipoprotein_level3.34704794
6MP0008875_abnormal_xenobiotic_pharmacok3.23317004
7MP0005670_abnormal_white_adipose2.87829526
8MP0005332_abnormal_amino_acid2.84559171
9MP0004130_abnormal_muscle_cell2.54800758
10MP0003880_abnormal_central_pattern2.48612277
11MP0003122_maternal_imprinting2.38743206
12MP0005666_abnormal_adipose_tissue2.22127527
13MP0002118_abnormal_lipid_homeostasis2.16573750
14MP0004019_abnormal_vitamin_homeostasis2.04274555
15MP0003252_abnormal_bile_duct2.02077222
16MP0003690_abnormal_glial_cell1.98487672
17MP0003136_yellow_coat_color1.97169648
18MP0003195_calcinosis1.91906610
19MP0004043_abnormal_pH_regulation1.87271161
20MP0004859_abnormal_synaptic_plasticity1.81295545
21MP0003806_abnormal_nucleotide_metabolis1.81026986
22MP0004147_increased_porphyrin_level1.79625850
23MP0002971_abnormal_brown_adipose1.74267277
24MP0009780_abnormal_chondrocyte_physiolo1.74069508
25MP0000778_abnormal_nervous_system1.72748095
26MP0002876_abnormal_thyroid_physiology1.71088949
27MP0003329_amyloid_beta_deposits1.69154097
28MP0004185_abnormal_adipocyte_glucose1.67959977
29MP0005535_abnormal_body_temperature1.67610388
30MP0003656_abnormal_erythrocyte_physiolo1.66653635
31MP0001666_abnormal_nutrient_absorption1.65996359
32MP0005584_abnormal_enzyme/coenzyme_acti1.60412377
33MP0004885_abnormal_endolymph1.59856169
34MP0000566_synostosis1.57342181
35MP0003011_delayed_dark_adaptation1.55265759
36MP0003186_abnormal_redox_activity1.53508540
37MP0006276_abnormal_autonomic_nervous1.52192414
38MP0009840_abnormal_foam_cell1.51174319
39MP0003283_abnormal_digestive_organ1.49243341
40MP0005423_abnormal_somatic_nervous1.49005620
41MP0005375_adipose_tissue_phenotype1.44501107
42MP0005083_abnormal_biliary_tract1.41797537
43MP0005646_abnormal_pituitary_gland1.41266356
44MP0003191_abnormal_cellular_cholesterol1.38822290
45MP0001501_abnormal_sleep_pattern1.38232917
46MP0000013_abnormal_adipose_tissue1.36043592
47MP0002909_abnormal_adrenal_gland1.35909442
48MP0000609_abnormal_liver_physiology1.35074781
49MP0002938_white_spotting1.30458521
50MP0009643_abnormal_urine_homeostasis1.29018355
51MP0002254_reproductive_system_inflammat1.23144342
52MP0001529_abnormal_vocalization1.22843396
53MP0003787_abnormal_imprinting1.19739183
54MP0002078_abnormal_glucose_homeostasis1.16201720
55MP0005334_abnormal_fat_pad1.15969074
56MP0003121_genomic_imprinting1.15968985
57MP0003635_abnormal_synaptic_transmissio1.15589829
58MP0005386_behavior/neurological_phenoty1.14787621
59MP0004924_abnormal_behavior1.14787621
60MP0001486_abnormal_startle_reflex1.14160446
61MP0005377_hearing/vestibular/ear_phenot1.13782838
62MP0003878_abnormal_ear_physiology1.13782838
63MP0006036_abnormal_mitochondrial_physio1.13765020
64MP0001485_abnormal_pinna_reflex1.13064431
65MP0004270_analgesia1.12469396
66MP0005319_abnormal_enzyme/_coenzyme1.12179284
67MP0003633_abnormal_nervous_system1.10410001
68MP0001764_abnormal_homeostasis1.10100735
69MP0000604_amyloidosis1.09436422
70MP0009745_abnormal_behavioral_response1.08782540
71MP0004858_abnormal_nervous_system1.07614115
72MP0002090_abnormal_vision1.05025497
73MP0003868_abnormal_feces_composition1.04908709
74MP0004133_heterotaxia1.04474362
75MP0002064_seizures1.04310769
76MP0005448_abnormal_energy_balance1.03929624
77MP0005636_abnormal_mineral_homeostasis1.03853351
78MP0005647_abnormal_sex_gland1.01942384
79MP0002063_abnormal_learning/memory/cond0.99705284
80MP0009115_abnormal_fat_cell0.99660141
81MP0009046_muscle_twitch0.99575875
82MP0002837_dystrophic_cardiac_calcinosis0.99389933
83MP0005253_abnormal_eye_physiology0.99052343
84MP0001756_abnormal_urination0.98410463
85MP0005167_abnormal_blood-brain_barrier0.98311592
86MP0004215_abnormal_myocardial_fiber0.96811254
87MP0002736_abnormal_nociception_after0.96457521
88MP0000955_abnormal_spinal_cord0.96389846
89MP0003890_abnormal_embryonic-extraembry0.95660863
90MP0008569_lethality_at_weaning0.95407114
91MP0002735_abnormal_chemical_nociception0.95229802
92MP0001984_abnormal_olfaction0.95157460
93MP0000003_abnormal_adipose_tissue0.94744202
94MP0001905_abnormal_dopamine_level0.92688836
95MP0010030_abnormal_orbit_morphology0.92313035
96MP0003123_paternal_imprinting0.91038085
97MP0001970_abnormal_pain_threshold0.90752392
98MP0008872_abnormal_physiological_respon0.90488881
99MP0002734_abnormal_mechanical_nocicepti0.90484846
100MP0001968_abnormal_touch/_nociception0.89855402
101MP0002572_abnormal_emotion/affect_behav0.88960337
102MP0003879_abnormal_hair_cell0.86797957
103MP0002272_abnormal_nervous_system0.86662495
104MP0003119_abnormal_digestive_system0.85343182
105MP0003953_abnormal_hormone_level0.85254361
106MP0002638_abnormal_pupillary_reflex0.85017232
107MP0003631_nervous_system_phenotype0.84942363
108MP0002184_abnormal_innervation0.84500492
109MP0006292_abnormal_olfactory_placode0.84347326
110MP0002882_abnormal_neuron_morphology0.84119373
111MP0001765_abnormal_ion_homeostasis0.83988651
112MP0006072_abnormal_retinal_apoptosis0.83898599
113MP0000026_abnormal_inner_ear0.83880070
114MP0001177_atelectasis0.83475699
115MP0005645_abnormal_hypothalamus_physiol0.82833039
116MP0002733_abnormal_thermal_nociception0.82617306
117MP0004272_abnormal_basement_membrane0.81893676
118MP0001944_abnormal_pancreas_morphology0.81437850
119MP0002102_abnormal_ear_morphology0.80935965
120MP0000631_abnormal_neuroendocrine_gland0.80891566
121MP0001502_abnormal_circadian_rhythm0.79370254
122MP0001661_extended_life_span0.78218928
123MP0002970_abnormal_white_adipose0.77918053
124MP0005084_abnormal_gallbladder_morpholo0.77528549
125MP0002822_catalepsy0.77522714
126MP0001440_abnormal_grooming_behavior0.76299799
127MP0002069_abnormal_eating/drinking_beha0.75722678
128MP0002152_abnormal_brain_morphology0.74647329
129MP0000647_abnormal_sebaceous_gland0.73830206
130MP0001293_anophthalmia0.72998548
131MP0005551_abnormal_eye_electrophysiolog0.72994424
132MP0003075_altered_response_to0.72106986
133MP0002067_abnormal_sensory_capabilities0.71998129
134MP0003646_muscle_fatigue0.70774319
135MP0005452_abnormal_adipose_tissue0.68175290
136MP0000230_abnormal_systemic_arterial0.66905312
137MP0002138_abnormal_hepatobiliary_system0.65048517
138MP0005595_abnormal_vascular_smooth0.64825400
139MP0009697_abnormal_copulation0.63758957
140MP0003959_abnormal_lean_body0.63679557
141MP0002557_abnormal_social/conspecific_i0.61756505
142MP0003638_abnormal_response/metabolism_0.61315952

Predicted human phenotypes

RankGene SetZ-score
1Hyperglycinuria (HP:0003108)5.10542546
2Abnormality of glycine metabolism (HP:0010895)4.70280517
3Abnormality of serine family amino acid metabolism (HP:0010894)4.70280517
4Hypoglycemic coma (HP:0001325)4.27684755
5Abnormality of aromatic amino acid family metabolism (HP:0004338)4.09506700
6Hyperammonemia (HP:0001987)4.06240274
7Xanthomatosis (HP:0000991)4.05626660
8Ketosis (HP:0001946)4.05343767
9Ketoacidosis (HP:0001993)4.02719112
10Hyperlipoproteinemia (HP:0010980)3.96548636
11Hyperglycinemia (HP:0002154)3.87808647
12Intrahepatic cholestasis (HP:0001406)3.76217973
13Deep venous thrombosis (HP:0002625)3.39099830
14Abnormality of glutamine family amino acid metabolism (HP:0010902)3.23497071
15Abnormality of fatty-acid metabolism (HP:0004359)3.22206303
16Epidermoid cyst (HP:0200040)3.18611481
17Hypoalphalipoproteinemia (HP:0003233)3.09628108
18Hypobetalipoproteinemia (HP:0003563)3.04986302
19Hemorrhage of the eye (HP:0011885)3.00395819
20Complement deficiency (HP:0004431)2.97567299
21Hypolipoproteinemia (HP:0010981)2.95890306
22Hypoglycemic seizures (HP:0002173)2.90283016
23Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.87590826
24Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.84640457
25Delayed CNS myelination (HP:0002188)2.80307547
26Gout (HP:0001997)2.78491337
27Dicarboxylic aciduria (HP:0003215)2.76013489
28Abnormality of dicarboxylic acid metabolism (HP:0010995)2.76013489
29Conjugated hyperbilirubinemia (HP:0002908)2.75031911
30Hyperventilation (HP:0002883)2.73030687
31Limb dystonia (HP:0002451)2.72547534
32Metabolic acidosis (HP:0001942)2.71666199
33Oligomenorrhea (HP:0000876)2.65695068
34Hydroxyprolinuria (HP:0003080)2.62986164
35Abnormality of proline metabolism (HP:0010907)2.62986164
36Abnormality of monocarboxylic acid metabolism (HP:0010996)2.60733686
37Focal seizures (HP:0007359)2.60270990
38Abnormality of purine metabolism (HP:0004352)2.59170128
39Hemiparesis (HP:0001269)2.55570088
40Prolonged partial thromboplastin time (HP:0003645)2.52988838
41Increased serum pyruvate (HP:0003542)2.49515659
42Hyperbilirubinemia (HP:0002904)2.47226955
43Hyperinsulinemic hypoglycemia (HP:0000825)2.45861133
44Acanthocytosis (HP:0001927)2.43028807
45Sensorimotor neuropathy (HP:0007141)2.42387309
46Poikilocytosis (HP:0004447)2.42065335
47Generalized aminoaciduria (HP:0002909)2.42055442
48Lethargy (HP:0001254)2.40192661
49Hypertriglyceridemia (HP:0002155)2.38402656
50Abnormality of aspartate family amino acid metabolism (HP:0010899)2.37420421
51Status epilepticus (HP:0002133)2.35122460
52Cholelithiasis (HP:0001081)2.34170425
53Abnormal gallbladder morphology (HP:0012437)2.33417433
54Hypercholesterolemia (HP:0003124)2.31445335
55Gait imbalance (HP:0002141)2.31322636
56Myoglobinuria (HP:0002913)2.28394774
57Facial shape deformation (HP:0011334)2.28361687
58Potter facies (HP:0002009)2.28361687
59Abnormality of glycolysis (HP:0004366)2.26309072
60Vaginal atresia (HP:0000148)2.24623619
61Abnormality of serum amino acid levels (HP:0003112)2.22202124
62Genital tract atresia (HP:0001827)2.22125826
63Abnormality of sulfur amino acid metabolism (HP:0004339)2.21328676
64Enlarged kidneys (HP:0000105)2.19325550
65Medial flaring of the eyebrow (HP:0010747)2.18664939
66Abnormal eating behavior (HP:0100738)2.17808530
67Vomiting (HP:0002013)2.17564032
68True hermaphroditism (HP:0010459)2.17432204
69Megalencephaly (HP:0001355)2.15226330
70Neurofibrillary tangles (HP:0002185)2.15196968
71Increased purine levels (HP:0004368)2.13436468
72Hyperuricemia (HP:0002149)2.13436468
73Late onset (HP:0003584)2.11959348
74Confusion (HP:0001289)2.11259679
75Hypokalemic alkalosis (HP:0001949)2.10983780
76Abnormal gallbladder physiology (HP:0012438)2.10960934
77Cholecystitis (HP:0001082)2.10960934
78Proximal tubulopathy (HP:0000114)2.09792827
79Symptomatic seizures (HP:0011145)2.08920815
80Acanthosis nigricans (HP:0000956)2.08466688
81Methylmalonic aciduria (HP:0012120)2.08408517
82Fat malabsorption (HP:0002630)2.07992970
83Increased circulating renin level (HP:0000848)2.06783632
84Metabolic alkalosis (HP:0200114)2.05703212
85Cerebral edema (HP:0002181)2.05605553
86Renal tubular acidosis (HP:0001947)2.02937135
87Congenital primary aphakia (HP:0007707)2.01208777
88Pheochromocytoma (HP:0002666)2.00044508
89Focal motor seizures (HP:0011153)2.00018398
90Anxiety (HP:0000739)1.99034837
91Prominent supraorbital ridges (HP:0000336)1.97761258
92Increased muscle lipid content (HP:0009058)1.95208646
93Hepatoblastoma (HP:0002884)1.93414937
94Generalized tonic-clonic seizures (HP:0002069)1.92944224
95Intention tremor (HP:0002080)1.92134079
96Vascular calcification (HP:0004934)1.92055286
97Clumsiness (HP:0002312)1.91934313
98Alkalosis (HP:0001948)1.90489249
99Enlarged penis (HP:0000040)1.90155523
100Cerebral inclusion bodies (HP:0100314)1.88793727
101Nausea (HP:0002018)1.87808616
102Irritability (HP:0000737)1.87362145
103Renal hypoplasia (HP:0000089)1.87326812
104Abnormality of nucleobase metabolism (HP:0010932)1.85987641
105Intestinal atresia (HP:0011100)1.85875185
106Dysdiadochokinesis (HP:0002075)1.85487370
107Abnormality of the labia minora (HP:0012880)1.83892900
108Large for gestational age (HP:0001520)1.83500789
109Methylmalonic acidemia (HP:0002912)1.82810809
110Polyphagia (HP:0002591)1.82326493
111Febrile seizures (HP:0002373)1.81117071
112Abnormality of the lower motor neuron (HP:0002366)1.80866776
113Myokymia (HP:0002411)1.80428127
114Retinal atrophy (HP:0001105)1.80398077
115Skin nodule (HP:0200036)1.80063905
116Bile duct proliferation (HP:0001408)1.79699870
117Abnormal biliary tract physiology (HP:0012439)1.79699870
118Nephrogenic diabetes insipidus (HP:0009806)1.79597905
119Abnormal urine output (HP:0012590)1.79433012
120Action tremor (HP:0002345)1.78990479
121Drooling (HP:0002307)1.78787931
122Nephronophthisis (HP:0000090)1.78046543
123Pancreatitis (HP:0001733)1.77478169
124Abnormality of the gallbladder (HP:0005264)1.77427545
125Hypochromic microcytic anemia (HP:0004840)1.77189449
126Insulin-resistant diabetes mellitus (HP:0000831)1.75457834
127Abnormality of alanine metabolism (HP:0010916)1.73233717
128Hyperalaninemia (HP:0003348)1.73233717
129Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.73233717
130Pancreatic fibrosis (HP:0100732)1.73211607
131Septo-optic dysplasia (HP:0100842)1.72269041
132Abnormality of midbrain morphology (HP:0002418)1.71312766
133Molar tooth sign on MRI (HP:0002419)1.71312766
134Poor suck (HP:0002033)1.70341864
135Epileptiform EEG discharges (HP:0011182)1.67747731
136Anophthalmia (HP:0000528)1.66953546
137Amblyopia (HP:0000646)1.62483619
138Dialeptic seizures (HP:0011146)1.62482839
139Acute encephalopathy (HP:0006846)1.62058219
140Abnormality of the vitreous humor (HP:0004327)1.61863392
141Hypsarrhythmia (HP:0002521)1.60043409
142Progressive macrocephaly (HP:0004481)1.59564469
143Abnormality of urine glucose concentration (HP:0011016)1.59458690
144Glycosuria (HP:0003076)1.59458690
145Pancreatic cysts (HP:0001737)1.59402790
146Epileptic encephalopathy (HP:0200134)1.59119775
147EEG with generalized epileptiform discharges (HP:0011198)1.58767355
148Atonic seizures (HP:0010819)1.58205767
149Acute necrotizing encephalopathy (HP:0006965)1.57243124
150Bicornuate uterus (HP:0000813)1.57211253
151Abnormal sex determination (HP:0012244)1.55296841
152Sex reversal (HP:0012245)1.55296841
153Pachygyria (HP:0001302)1.54915703
154Progressive cerebellar ataxia (HP:0002073)1.54887559
155Occipital encephalocele (HP:0002085)1.53422090
156Abnormality of vitamin metabolism (HP:0100508)1.52858451
157Hypothermia (HP:0002045)1.51253433
158Hepatic necrosis (HP:0002605)1.51201345
159Broad-based gait (HP:0002136)1.50398444
160Specific learning disability (HP:0001328)1.49999141
161Sclerocornea (HP:0000647)1.49035349
162Renal cortical cysts (HP:0000803)1.48783587
163Coronal craniosynostosis (HP:0004440)1.48574131
164Bronchomalacia (HP:0002780)1.48421245
165Broad foot (HP:0001769)1.48133751
166Spastic tetraplegia (HP:0002510)1.47777717
167Pigmentary retinal degeneration (HP:0001146)1.47744018
168Absence seizures (HP:0002121)1.46947455
169Poor coordination (HP:0002370)1.45163781

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.37136989
2BCKDK3.53346154
3CAMK1D3.10301495
4CAMK1G2.77468070
5SIK12.69850069
6LMTK22.67953622
7EPHB22.45729527
8EPHA42.34288447
9SGK2232.24917920
10SGK4942.24917920
11SGK22.21854682
12PINK12.09237500
13PDK32.04148107
14PDK42.04148107
15PNCK2.01534840
16SGK32.00641076
17PRKD31.99389941
18MAP4K21.80860238
19NTRK21.76312056
20INSRR1.74413988
21WNK31.73618063
22NTRK31.70386735
23BMPR1B1.67645722
24PHKG11.65925178
25PHKG21.65925178
26CASK1.62656350
27WNK41.59372268
28MAP2K41.47625382
29MST1R1.43013319
30MAP3K41.42917262
31DAPK21.42053361
32OXSR11.35550628
33LATS11.35164835
34MAPK131.32725721
35PRKAA21.22886063
36DYRK21.16561897
37PAK61.15491221
38LATS21.14205907
39UHMK11.12600285
40NTRK11.07736991
41TYRO31.06613031
42STK38L1.06145064
43PDPK11.06100356
44FRK1.05759825
45MAP2K71.04885498
46CAMKK11.02650882
47MAP3K91.01993404
48PRKAA11.01527049
49MAPK151.01400351
50MINK11.00460178
51MAP3K20.90650945
52STK390.89585764
53FGFR20.88034764
54PDK20.86844430
55CDK50.86540639
56PDK10.85771541
57ACVR1B0.84716990
58BCR0.84716951
59RIPK10.78962109
60MUSK0.77941044
61TSSK60.77580844
62PRKACG0.77380171
63CAMKK20.75779606
64SGK10.74648613
65LIMK10.74484519
66CAMK2D0.74243646
67EPHA30.73892271
68STK380.73641825
69ERN10.73362380
70LRRK20.72361195
71MAP2K10.72227579
72CAMK10.71961146
73TRIM280.71852528
74CSNK1G30.71723507
75PTK2B0.71153073
76PRKCG0.70424910
77GRK50.69143163
78MARK10.67486680
79KSR20.66767154
80ABL20.65463277
81TIE10.64702396
82MKNK20.64630556
83GRK60.64459737
84TGFBR10.64420086
85WNK10.61948851
86ADRBK20.61029876
87FGFR40.60626068
88RET0.60462440
89CDK90.60132217
90PLK20.59096661
91FER0.58697866
92CAMK2G0.57632893
93PRKCH0.56449089
94RPS6KB10.55906536
95PRKCZ0.55725109
96PIK3CA0.55540093
97CSNK1A1L0.54575677
98MAPK110.53840916
99PRKCQ0.53785348
100TNK20.53671176
101NLK0.53630884
102MAP3K70.53530506
103ERBB40.52875764
104MAPK120.52725315
105MET0.51753239
106DYRK1A0.51536558
107ERBB20.51447014
108CSNK1G20.51285932
109CSNK1E0.50292034
110CAMK2A0.50228847
111ERBB30.50119791
112PRKCE0.50028211
113ROCK20.49879829
114RPS6KA30.49588212
115FGFR10.49229680
116TESK10.49043846
117STK110.48881193
118GRK10.48758073
119PKN10.48482310
120TNIK0.48227902
121PTK20.47944156
122PRKG20.47897094
123PLK30.47285125
124CDK180.46639288
125CSNK1A10.46189367
126MAP3K120.46019380
127CDK150.45845654
128PTK60.45425742
129PRKACB0.45365679
130CAMK2B0.44849866
131ROCK10.44701274
132PRKG10.44242558
133PRKACA0.43929124
134ARAF0.42781752
135PAK30.42066963
136MST40.41806849
137PRKCA0.40766390
138PKN20.40393918
139CSNK1G10.40087530
140PRKD10.38887525
141EPHB10.38171733
142CDK60.38153912
143JAK20.37014978

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009106.16146740
2Propanoate metabolism_Homo sapiens_hsa006402.84899031
3Fatty acid degradation_Homo sapiens_hsa000712.65297177
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.60824585
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.57056534
6Fatty acid metabolism_Homo sapiens_hsa012122.53218881
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.46208725
8Butanoate metabolism_Homo sapiens_hsa006502.43035810
9Primary bile acid biosynthesis_Homo sapiens_hsa001202.36920591
10PPAR signaling pathway_Homo sapiens_hsa033202.36241723
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.35855728
12Fatty acid biosynthesis_Homo sapiens_hsa000612.22603492
13Arginine biosynthesis_Homo sapiens_hsa002202.13779485
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.91131427
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88701971
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.86906587
17Pyruvate metabolism_Homo sapiens_hsa006201.85615546
18Peroxisome_Homo sapiens_hsa041461.82007948
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.76250180
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74834617
21Tryptophan metabolism_Homo sapiens_hsa003801.69780617
22beta-Alanine metabolism_Homo sapiens_hsa004101.62501978
23Fatty acid elongation_Homo sapiens_hsa000621.57334115
24Sulfur metabolism_Homo sapiens_hsa009201.52498768
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.45124594
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.42200888
27Bile secretion_Homo sapiens_hsa049761.39338947
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.36595428
29Caffeine metabolism_Homo sapiens_hsa002321.34747131
30Carbon metabolism_Homo sapiens_hsa012001.32760822
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.31247973
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.28891699
33Glycerolipid metabolism_Homo sapiens_hsa005611.19251043
34Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.16008780
35Chemical carcinogenesis_Homo sapiens_hsa052041.13696290
36Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.11530674
37Histidine metabolism_Homo sapiens_hsa003401.10825105
38Complement and coagulation cascades_Homo sapiens_hsa046101.04304773
39Fat digestion and absorption_Homo sapiens_hsa049751.02166731
40Starch and sucrose metabolism_Homo sapiens_hsa005000.95304540
41Parkinsons disease_Homo sapiens_hsa050120.94125658
42Vitamin B6 metabolism_Homo sapiens_hsa007500.93908930
43Retinol metabolism_Homo sapiens_hsa008300.93554935
44Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91964402
45Cardiac muscle contraction_Homo sapiens_hsa042600.90324324
46Biosynthesis of amino acids_Homo sapiens_hsa012300.89236587
47Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.88184198
48Phenylalanine metabolism_Homo sapiens_hsa003600.87361386
49Linoleic acid metabolism_Homo sapiens_hsa005910.84498215
50Protein export_Homo sapiens_hsa030600.83981300
51Dopaminergic synapse_Homo sapiens_hsa047280.83434528
52Tyrosine metabolism_Homo sapiens_hsa003500.83136044
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82873047
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.81514480
55Amphetamine addiction_Homo sapiens_hsa050310.79567301
56Alzheimers disease_Homo sapiens_hsa050100.78116323
57Cocaine addiction_Homo sapiens_hsa050300.77983832
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.77939007
59Phototransduction_Homo sapiens_hsa047440.76666186
60ABC transporters_Homo sapiens_hsa020100.75196289
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.73830262
62Ovarian steroidogenesis_Homo sapiens_hsa049130.72831633
63GABAergic synapse_Homo sapiens_hsa047270.71319954
64Vitamin digestion and absorption_Homo sapiens_hsa049770.71299347
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.69920817
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69782713
67Adipocytokine signaling pathway_Homo sapiens_hsa049200.67362653
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65804965
69Steroid biosynthesis_Homo sapiens_hsa001000.64278894
70Basal cell carcinoma_Homo sapiens_hsa052170.63966810
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.61193135
72Huntingtons disease_Homo sapiens_hsa050160.58567372
73Serotonergic synapse_Homo sapiens_hsa047260.58139625
74Axon guidance_Homo sapiens_hsa043600.57854070
75Glutathione metabolism_Homo sapiens_hsa004800.57192617
76Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55611187
77Arginine and proline metabolism_Homo sapiens_hsa003300.55590863
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54712030
79Sulfur relay system_Homo sapiens_hsa041220.53888212
80Folate biosynthesis_Homo sapiens_hsa007900.53424637
81Synaptic vesicle cycle_Homo sapiens_hsa047210.51779385
82Nicotine addiction_Homo sapiens_hsa050330.50861281
83Salivary secretion_Homo sapiens_hsa049700.50600477
84Glucagon signaling pathway_Homo sapiens_hsa049220.50492590
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50397667
86Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50326947
87Ether lipid metabolism_Homo sapiens_hsa005650.49474322
88Taste transduction_Homo sapiens_hsa047420.48942459
89Gastric acid secretion_Homo sapiens_hsa049710.48700916
90Hedgehog signaling pathway_Homo sapiens_hsa043400.47253856
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.47243849
92Selenocompound metabolism_Homo sapiens_hsa004500.46993027
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46222904
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.44436621
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.44417869
96Glutamatergic synapse_Homo sapiens_hsa047240.43814440
97Hippo signaling pathway_Homo sapiens_hsa043900.43004041
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42853321
99AMPK signaling pathway_Homo sapiens_hsa041520.41806663
100Fructose and mannose metabolism_Homo sapiens_hsa000510.41124106
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.40459390
102Mineral absorption_Homo sapiens_hsa049780.40417317
103Melanogenesis_Homo sapiens_hsa049160.40349451
104Insulin secretion_Homo sapiens_hsa049110.39304188
105Pentose phosphate pathway_Homo sapiens_hsa000300.37254836
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.37179533
107Metabolic pathways_Homo sapiens_hsa011000.36882508
108Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.35973177
109Renin secretion_Homo sapiens_hsa049240.35905111
110Insulin resistance_Homo sapiens_hsa049310.34421546
111Lysine degradation_Homo sapiens_hsa003100.33817427
112Collecting duct acid secretion_Homo sapiens_hsa049660.32864260
113Circadian entrainment_Homo sapiens_hsa047130.32051795
114Thyroid hormone synthesis_Homo sapiens_hsa049180.30428913
115Circadian rhythm_Homo sapiens_hsa047100.30420755
116Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.28821318
117Morphine addiction_Homo sapiens_hsa050320.28510997
118Staphylococcus aureus infection_Homo sapiens_hsa051500.26995284
119Insulin signaling pathway_Homo sapiens_hsa049100.22568182
120Galactose metabolism_Homo sapiens_hsa000520.22044545
121alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.21897538
122Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19847849
123Olfactory transduction_Homo sapiens_hsa047400.19391718
124cAMP signaling pathway_Homo sapiens_hsa040240.18434127
125Oxidative phosphorylation_Homo sapiens_hsa001900.16863042
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.14908270

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