FAM217A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.94094151
2cell-cell recognition (GO:0009988)9.84103167
3binding of sperm to zona pellucida (GO:0007339)9.71241160
4motile cilium assembly (GO:0044458)9.41221719
5negative regulation of cytosolic calcium ion concentration (GO:0051481)9.32170817
6regulation of cilium movement (GO:0003352)9.04162423
7cilium movement (GO:0003341)8.80005593
8negative regulation of cAMP-mediated signaling (GO:0043951)8.64136727
9spermatid development (GO:0007286)8.51860677
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.51698200
11single fertilization (GO:0007338)8.00835915
12synapsis (GO:0007129)7.38033643
13piRNA metabolic process (GO:0034587)7.35001306
14male meiosis (GO:0007140)7.22139996
15DNA synthesis involved in DNA repair (GO:0000731)6.63013160
16sperm capacitation (GO:0048240)6.62168978
17opioid receptor signaling pathway (GO:0038003)6.60712468
18fertilization (GO:0009566)6.56267435
19synaptonemal complex organization (GO:0070193)6.38597240
20negative regulation of calcium ion-dependent exocytosis (GO:0045955)6.29543028
21ether lipid metabolic process (GO:0046485)6.24879841
22synaptonemal complex assembly (GO:0007130)6.22318785
23behavioral response to ethanol (GO:0048149)6.17026842
24microtubule depolymerization (GO:0007019)5.87705113
25regulation of acrosome reaction (GO:0060046)5.79698473
26protein localization to cilium (GO:0061512)5.74648326
27spermatid nucleus differentiation (GO:0007289)5.72374369
28spermatogenesis (GO:0007283)5.70473522
29male gamete generation (GO:0048232)5.68323722
30adult feeding behavior (GO:0008343)5.66236220
31negative regulation of inclusion body assembly (GO:0090084)5.44984148
32regulation of translational termination (GO:0006449)5.43288747
33adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.33968616
34protein targeting to Golgi (GO:0000042)5.32382499
35establishment of protein localization to Golgi (GO:0072600)5.32268485
36gamete generation (GO:0007276)5.30007709
37microtubule severing (GO:0051013)5.25844056
38regulation of microtubule-based movement (GO:0060632)5.25410018
39organic cation transport (GO:0015695)5.23968908
40calcium ion-dependent exocytosis (GO:0017156)5.22185207
41ventricular system development (GO:0021591)5.04802812
42cellular process involved in reproduction in multicellular organism (GO:0022412)4.90146273
43cell recognition (GO:0008037)4.87183072
44retrograde transport, vesicle recycling within Golgi (GO:0000301)4.81923610
45germ cell development (GO:0007281)4.80729630
46rRNA methylation (GO:0031167)4.80440538
47DNA methylation involved in gamete generation (GO:0043046)4.78012970
48sensory perception of smell (GO:0007608)4.76179896
49sphingosine metabolic process (GO:0006670)4.75041682
50sister chromatid cohesion (GO:0007062)4.74984441
51regulation of protein glycosylation (GO:0060049)4.74253570
52protein polyglutamylation (GO:0018095)4.70124696
53regulation of inclusion body assembly (GO:0090083)4.62898457
54male meiosis I (GO:0007141)4.59767457
55positive regulation of cAMP-mediated signaling (GO:0043950)4.57611071
56intraciliary transport (GO:0042073)4.54770251
57glomerular visceral epithelial cell development (GO:0072015)4.49366008
58chromosome organization involved in meiosis (GO:0070192)4.29429148
59axoneme assembly (GO:0035082)4.29012302
60diol metabolic process (GO:0034311)4.27793090
61DNA replication-dependent nucleosome organization (GO:0034723)4.22394086
62DNA replication-dependent nucleosome assembly (GO:0006335)4.22394086
63multicellular organismal reproductive process (GO:0048609)4.20927506
64glycerol ether metabolic process (GO:0006662)4.19247219
65phosphatidylethanolamine biosynthetic process (GO:0006646)4.18815530
66meiotic nuclear division (GO:0007126)4.15133893
67cilium morphogenesis (GO:0060271)4.12648122
68glomerular epithelial cell development (GO:0072310)4.02290154
69centriole assembly (GO:0098534)4.00402668
70sphingoid metabolic process (GO:0046519)3.98869550
71centriole replication (GO:0007099)3.95361656
72protein localization to Golgi apparatus (GO:0034067)3.93064614
73phosphatidylethanolamine metabolic process (GO:0046337)3.92710220
74rRNA modification (GO:0000154)3.90042552
75resolution of meiotic recombination intermediates (GO:0000712)3.87910544
76ether metabolic process (GO:0018904)3.85968238
77negative regulation of nitric oxide biosynthetic process (GO:0045019)3.83286791
78notochord development (GO:0030903)3.80580757
79mRNA cleavage (GO:0006379)3.76068262
80monoubiquitinated protein deubiquitination (GO:0035520)3.75438149
81meiotic cell cycle (GO:0051321)3.73011232
82regulation of chromatin binding (GO:0035561)3.69080994
83cilium organization (GO:0044782)3.67878231
84response to pheromone (GO:0019236)3.67676897
85cilium assembly (GO:0042384)3.65557135
86meiosis I (GO:0007127)3.63575877
87ncRNA catabolic process (GO:0034661)3.61128764
88single strand break repair (GO:0000012)3.60621276
89protein insertion into membrane (GO:0051205)3.59057942
90thrombin receptor signaling pathway (GO:0070493)3.53319927
91left/right pattern formation (GO:0060972)3.45784821
92sexual reproduction (GO:0019953)3.42397797
93regulation of cAMP-mediated signaling (GO:0043949)3.39966835
94protein K11-linked deubiquitination (GO:0035871)3.39492950
95chromosome condensation (GO:0030261)3.38130386
96multicellular organismal development (GO:0007275)3.33394996
97reciprocal DNA recombination (GO:0035825)3.31470328
98reciprocal meiotic recombination (GO:0007131)3.31470328
99cellular component assembly involved in morphogenesis (GO:0010927)3.30314148
100coenzyme catabolic process (GO:0009109)3.29421657
101cellular response to ammonium ion (GO:0071242)3.24580371
102seminiferous tubule development (GO:0072520)3.22972973
103regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.20691043
104microtubule-based movement (GO:0007018)3.18942136
105polyol catabolic process (GO:0046174)3.18328448
106sensory perception of chemical stimulus (GO:0007606)3.14975884
107DNA packaging (GO:0006323)3.14697105
108meiotic chromosome segregation (GO:0045132)3.13386730
109cellular ketone body metabolic process (GO:0046950)3.12780789
110microtubule polymerization or depolymerization (GO:0031109)3.06966501
111nucleoside diphosphate phosphorylation (GO:0006165)3.00754657
112chaperone-mediated protein complex assembly (GO:0051131)3.00578028
113genitalia morphogenesis (GO:0035112)3.00402944
114sequestering of actin monomers (GO:0042989)2.96806161
115lactate metabolic process (GO:0006089)2.92428744
116alditol metabolic process (GO:0019400)2.86306556
117peptidyl-threonine dephosphorylation (GO:0035970)2.82125295
118regulation of meiosis I (GO:0060631)2.74491269
119gene silencing by RNA (GO:0031047)2.72428914
120peptidyl-glutamic acid modification (GO:0018200)2.72309935
121meiotic cell cycle process (GO:1903046)2.66494592
122nucleus organization (GO:0006997)2.66224784
123glycerol metabolic process (GO:0006071)2.63946343
124GTP biosynthetic process (GO:0006183)2.60408224
125regulation of spindle checkpoint (GO:0090231)2.50441505
126regulation of female gonad development (GO:2000194)2.48629029
127glycolytic process (GO:0006096)2.47868773
128regulation of centriole replication (GO:0046599)2.47281745
129microtubule bundle formation (GO:0001578)2.46181139
130carnitine transport (GO:0015879)2.43994538
131amino-acid betaine transport (GO:0015838)2.43994538
132protein refolding (GO:0042026)2.43965955
133left/right axis specification (GO:0070986)2.43735949
134fusion of sperm to egg plasma membrane (GO:0007342)14.1315073
135cell wall macromolecule catabolic process (GO:0016998)13.9405519
136cell wall macromolecule metabolic process (GO:0044036)13.9405519
137multicellular organism reproduction (GO:0032504)11.8029310
138sperm motility (GO:0030317)11.6014346
139cilium or flagellum-dependent cell motility (GO:0001539)11.3346655
140sperm-egg recognition (GO:0035036)10.9686380
141plasma membrane fusion (GO:0045026)10.7909879
142axonemal dynein complex assembly (GO:0070286)10.5773189
143acrosome assembly (GO:0001675)10.5594668
144acrosome reaction (GO:0007340)10.4007679
145epithelial cilium movement (GO:0003351)10.3153377

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.10535759
2EZH2_22144423_ChIP-Seq_EOC_Human4.67975177
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.54140390
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.11932570
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.93005723
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.86921517
7MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.39483837
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.36914003
9FUS_26573619_Chip-Seq_HEK293_Human2.26640733
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.26142263
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.24894564
12KAP1_22055183_ChIP-Seq_ESCs_Mouse2.08175208
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.07971392
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.06896960
15VDR_22108803_ChIP-Seq_LS180_Human2.04573931
16CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.95450785
17POU3F2_20337985_ChIP-ChIP_501MEL_Human1.90963169
18CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88565190
19KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.87267340
20ER_23166858_ChIP-Seq_MCF-7_Human1.86592073
21GATA1_26923725_Chip-Seq_HPCs_Mouse1.83305554
22EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.82494393
23STAT3_23295773_ChIP-Seq_U87_Human1.79786447
24STAT1_17558387_ChIP-Seq_HELA_Human1.78268859
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.78164258
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.74912280
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74617809
28TAF15_26573619_Chip-Seq_HEK293_Human1.73917843
29MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.73675936
30TAL1_26923725_Chip-Seq_HPCs_Mouse1.73647814
31NANOG_19829295_ChIP-Seq_ESCs_Human1.72978589
32SOX2_19829295_ChIP-Seq_ESCs_Human1.72978589
33KDM2B_26808549_Chip-Seq_REH_Human1.72622770
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70165389
35TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.67476324
36RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.65315226
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.64198205
38ELK4_26923725_Chip-Seq_MESODERM_Mouse1.63272722
39RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62891920
40WDR5_24793694_ChIP-Seq_LNCAP_Human1.62535499
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59646651
42VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.59215901
43AR_25329375_ChIP-Seq_VCAP_Human1.59159606
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.58965213
45P300_19829295_ChIP-Seq_ESCs_Human1.58552159
46ZNF274_21170338_ChIP-Seq_K562_Hela1.56928584
47SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.56040986
48TCF4_23295773_ChIP-Seq_U87_Human1.55342303
49RXR_22108803_ChIP-Seq_LS180_Human1.53630865
50TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.50941325
51GATA3_21867929_ChIP-Seq_CD8_Mouse1.50462830
52PCGF2_27294783_Chip-Seq_NPCs_Mouse1.47281199
53GATA3_21878914_ChIP-Seq_MCF-7_Human1.47167035
54SOX2_22085726_ChIP-Seq_NPCs_Mouse1.46528956
55GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.43839064
56GATA3_21867929_ChIP-Seq_TH1_Mouse1.43364504
57ERA_21632823_ChIP-Seq_H3396_Human1.43354105
58RAC3_21632823_ChIP-Seq_H3396_Human1.42620123
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.41615037
60SMAD3_21741376_ChIP-Seq_EPCs_Human1.41200726
61EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.41037590
62ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40619677
63RNF2_27304074_Chip-Seq_NSC_Mouse1.39815128
64BCAT_22108803_ChIP-Seq_LS180_Human1.39283250
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38157030
66TP63_19390658_ChIP-ChIP_HaCaT_Human1.36782313
67TP53_22573176_ChIP-Seq_HFKS_Human1.36765154
68PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.36724354
69PKCTHETA_26484144_Chip-Seq_BREAST_Human1.34923094
70GBX2_23144817_ChIP-Seq_PC3_Human1.34791190
71TDRD3_21172665_ChIP-Seq_MCF-7_Human1.34415033
72TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34192246
73POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34192246
74CDX2_22108803_ChIP-Seq_LS180_Human1.32736207
75RUNX1_26923725_Chip-Seq_HPCs_Mouse1.31720651
76GF1_26923725_Chip-Seq_HPCs_Mouse1.31515026
77RUNX2_22187159_ChIP-Seq_PCA_Human1.31188689
78IGF1R_20145208_ChIP-Seq_DFB_Human1.30697571
79CEBPB_22108803_ChIP-Seq_LS180_Human1.30118174
80FLI1_21867929_ChIP-Seq_TH2_Mouse1.29830645
81PRDM14_20953172_ChIP-Seq_ESCs_Human1.27727701
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27463531
83P53_22387025_ChIP-Seq_ESCs_Mouse1.27274082
84NANOG_18555785_Chip-Seq_ESCs_Mouse1.27142555
85MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26946814
86CBP_20019798_ChIP-Seq_JUKART_Human1.26813869
87IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26813869
88SMAD4_21799915_ChIP-Seq_A2780_Human1.26176081
89SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.25813438
90PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.25056269
91EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.24803619
92OCT4_20526341_ChIP-Seq_ESCs_Human1.24605848
93FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24124649
94CRX_20693478_ChIP-Seq_RETINA_Mouse1.23629006
95CMYC_18555785_Chip-Seq_ESCs_Mouse1.23365751
96TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22981549
97REST_21632747_ChIP-Seq_MESCs_Mouse1.22407364
98OCT4_18555785_Chip-Seq_ESCs_Mouse1.21764649
99TAF2_19829295_ChIP-Seq_ESCs_Human1.21546581
100CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21218005
101MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20598693
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19814862
103TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.19387289
104CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18916144
105LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.18043566
106PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.17352238
107P53_21459846_ChIP-Seq_SAOS-2_Human1.16549088
108FOXA1_21572438_ChIP-Seq_LNCaP_Human1.15258589
109AR_21572438_ChIP-Seq_LNCaP_Human1.14139705
110SUZ12_18555785_Chip-Seq_ESCs_Mouse1.13805294
111KLF4_18555785_Chip-Seq_ESCs_Mouse1.13641024
112EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.13579670
113TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.13318520
114FOXH1_21741376_ChIP-Seq_EPCs_Human1.13200586
115RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.13100978
116EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12897132
117MYC_19829295_ChIP-Seq_ESCs_Human1.12651025
118SOX2_18555785_Chip-Seq_ESCs_Mouse1.11431951
119P300_18555785_Chip-Seq_ESCs_Mouse1.11307902
120EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10389143
121FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09028232
122NFYB_21822215_ChIP-Seq_K562_Human1.08717422
123RBPJ_21746931_ChIP-Seq_IB4_Human1.08612642
124DROSHA_22980978_ChIP-Seq_HELA_Human1.08269091
125EZH2_27294783_Chip-Seq_NPCs_Mouse1.07690590
126FOXA1_25329375_ChIP-Seq_VCAP_Human1.07114766
127FOXA1_27270436_Chip-Seq_PROSTATE_Human1.07114766
128SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.07108025
129CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07067056
130STAT3_18555785_Chip-Seq_ESCs_Mouse1.06798124
131GF1B_26923725_Chip-Seq_HPCs_Mouse1.06595253
132CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06539856
133ESRRB_18555785_Chip-Seq_ESCs_Mouse1.06292714
134TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05251990
135TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05183196
136SMAD4_21741376_ChIP-Seq_EPCs_Human1.04658658
137GATA3_26560356_Chip-Seq_TH1_Human1.04225842
138TCF4_22108803_ChIP-Seq_LS180_Human1.03851179
139TP53_18474530_ChIP-ChIP_U2OS_Human1.02764248
140HOXB7_26014856_ChIP-Seq_BT474_Human1.02701905
141CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02577503
142RUNX1_27457419_Chip-Seq_LIVER_Mouse1.02569011
143HTT_18923047_ChIP-ChIP_STHdh_Human1.02180348
144CTCF_18555785_Chip-Seq_ESCs_Mouse1.01879529
145SPI1_26923725_Chip-Seq_HPCs_Mouse1.01632504
146OCT1_27270436_Chip-Seq_PROSTATE_Human1.01356482
147PU1_27457419_Chip-Seq_LIVER_Mouse0.99937656
148PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.99760037
149NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99673086
150ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99649977
151AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99524887
152ERG_20517297_ChIP-Seq_VCAP_Human0.99384040
153E2F1_18555785_Chip-Seq_ESCs_Mouse0.98730439
154OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97339614
155STAT3_18555785_ChIP-Seq_MESCs_Mouse0.97189970
156SOX9_26525672_Chip-Seq_HEART_Mouse0.95868699
157NANOG_20526341_ChIP-Seq_ESCs_Human0.95670433
158NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.95340544
159ESET_19884257_ChIP-Seq_ESCs_Mouse0.95312339
160SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94745561
161NMYC_18555785_Chip-Seq_ESCs_Mouse0.94210191
162NFIB_24661679_ChIP-Seq_LUNG_Mouse0.93618942
163ZFX_18555785_Chip-Seq_ESCs_Mouse0.93306869
164RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.92991179
165ETV1_20927104_ChIP-Seq_GIST48_Human0.91412290
166SMAD1_18555785_Chip-Seq_ESCs_Mouse0.90506592
167KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.90346573

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction6.06788881
2MP0003698_abnormal_male_reproductive5.44430700
3MP0001929_abnormal_gametogenesis5.05276012
4MP0009278_abnormal_bone_marrow4.49512858
5MP0008877_abnormal_DNA_methylation4.34570315
6MP0002876_abnormal_thyroid_physiology3.62345072
7MP0009780_abnormal_chondrocyte_physiolo3.53320837
8MP0002210_abnormal_sex_determination3.52132993
9MP0001968_abnormal_touch/_nociception3.27294562
10MP0000678_abnormal_parathyroid_gland3.26381239
11MP0002653_abnormal_ependyma_morphology3.20201459
12MP0002161_abnormal_fertility/fecundity3.09083114
13MP0001145_abnormal_male_reproductive2.89998906
14MP0000653_abnormal_sex_gland2.64686566
15MP0005360_urolithiasis2.64184630
16MP0002160_abnormal_reproductive_system2.34224246
17MP0001501_abnormal_sleep_pattern2.13943227
18MP0005397_hematopoietic_system_phenotyp2.07836693
19MP0001545_abnormal_hematopoietic_system2.07836693
20MP0005503_abnormal_tendon_morphology2.05514649
21MP0005670_abnormal_white_adipose2.02926481
22MP0003950_abnormal_plasma_membrane2.01577346
23MP0005410_abnormal_fertilization13.8750855
24MP0002102_abnormal_ear_morphology1.96417482
25MP0008789_abnormal_olfactory_epithelium1.95924225
26MP0009764_decreased_sensitivity_to1.78546426
27MP0003880_abnormal_central_pattern1.78490894
28MP0000681_abnormal_thyroid_gland1.77708686
29MP0005310_abnormal_salivary_gland1.75940830
30MP0005623_abnormal_meninges_morphology1.74309899
31MP0005394_taste/olfaction_phenotype1.70214478
32MP0005499_abnormal_olfactory_system1.70214478
33MP0003646_muscle_fatigue1.54587535
34MP0002249_abnormal_larynx_morphology1.50809073
35MP0003878_abnormal_ear_physiology1.45535408
36MP0005377_hearing/vestibular/ear_phenot1.45535408
37MP0008058_abnormal_DNA_repair1.41850220
38MP0001986_abnormal_taste_sensitivity1.41387734
39MP0001664_abnormal_digestion1.40698508
40MP0004233_abnormal_muscle_weight1.38185444
41MP0000015_abnormal_ear_pigmentation1.36461160
42MP0003941_abnormal_skin_development1.30496716
43MP0005389_reproductive_system_phenotype1.30200094
44MP0002928_abnormal_bile_duct1.29620483
45MP0005645_abnormal_hypothalamus_physiol1.28857400
46MP0002282_abnormal_trachea_morphology1.16809641
47MP0003045_fibrosis1.14729287
48MP0004782_abnormal_surfactant_physiolog1.10531502
49MP0009333_abnormal_splenocyte_physiolog1.07848355
50MP0002272_abnormal_nervous_system1.04988941
51MP0003183_abnormal_peptide_metabolism1.03482332
52MP0005395_other_phenotype0.99681733
53MP0009745_abnormal_behavioral_response0.97836639
54MP0005423_abnormal_somatic_nervous0.96823142
55MP0002733_abnormal_thermal_nociception0.96445278
56MP0001765_abnormal_ion_homeostasis0.96282260
57MP0003959_abnormal_lean_body0.93024504
58MP0001293_anophthalmia0.92261544
59MP0009046_muscle_twitch0.90602453
60MP0001119_abnormal_female_reproductive0.89473805
61MP0005647_abnormal_sex_gland0.88247513
62MP0003195_calcinosis0.87801741
63MP0001485_abnormal_pinna_reflex0.85428320
64MP0010094_abnormal_chromosome_stability0.83169630
65MP0000230_abnormal_systemic_arterial0.79751158
66MP0003638_abnormal_response/metabolism_0.79451738
67MP0005551_abnormal_eye_electrophysiolog0.79063056
68MP0005083_abnormal_biliary_tract0.78193567
69MP0005167_abnormal_blood-brain_barrier0.76474005
70MP0008995_early_reproductive_senescence0.75497113
71MP0009765_abnormal_xenobiotic_induced0.74952971
72MP0004084_abnormal_cardiac_muscle0.73467014
73MP0003699_abnormal_female_reproductive0.72957809
74MP0003567_abnormal_fetal_cardiomyocyte0.69643025
75MP0002132_abnormal_respiratory_system0.69123558
76MP0008775_abnormal_heart_ventricle0.68452863
77MP0005666_abnormal_adipose_tissue0.68239065
78MP0002752_abnormal_somatic_nervous0.67809426
79MP0005174_abnormal_tail_pigmentation0.66770437
80MP0002067_abnormal_sensory_capabilities0.65444172
81MP0002168_other_aberrant_phenotype0.64594940
82MP0005084_abnormal_gallbladder_morpholo0.63760419
83MP0003631_nervous_system_phenotype0.63751766
84MP0001348_abnormal_lacrimal_gland0.62153640
85MP0002184_abnormal_innervation0.61888355
86MP0004036_abnormal_muscle_relaxation0.60668004
87MP0003718_maternal_effect0.59083540
88MP0002234_abnormal_pharynx_morphology0.59017455
89MP0001970_abnormal_pain_threshold0.58727896
90MP0002557_abnormal_social/conspecific_i0.57361647
91MP0004742_abnormal_vestibular_system0.57235094
92MP0003693_abnormal_embryo_hatching0.57040680
93MP0002095_abnormal_skin_pigmentation0.55402008
94MP0005332_abnormal_amino_acid0.55333472
95MP0001881_abnormal_mammary_gland0.55220368
96MP0002233_abnormal_nose_morphology0.54032286
97MP0003077_abnormal_cell_cycle0.53934592
98MP0002693_abnormal_pancreas_physiology0.53740584
99MP0005334_abnormal_fat_pad0.53598177
100MP0005636_abnormal_mineral_homeostasis0.53464238
101MP0000372_irregular_coat_pigmentation0.53048418
102MP0010307_abnormal_tumor_latency0.52555415
103MP0003787_abnormal_imprinting0.47440749
104MP0009643_abnormal_urine_homeostasis0.47413767
105MP0002152_abnormal_brain_morphology0.47208966
106MP0003861_abnormal_nervous_system0.46643611
107MP0000569_abnormal_digit_pigmentation0.46175506
108MP0003806_abnormal_nucleotide_metabolis0.46030874
109MP0000358_abnormal_cell_content/0.43346115
110MP0003252_abnormal_bile_duct0.42919921
111MP0001324_abnormal_eye_pigmentation0.42639827
112MP0001963_abnormal_hearing_physiology0.39435504
113MP0005646_abnormal_pituitary_gland0.38147501
114MP0002882_abnormal_neuron_morphology0.37158465
115MP0000026_abnormal_inner_ear0.34647921
116MP0009115_abnormal_fat_cell0.34499704
117MP0005195_abnormal_posterior_eye0.34351974
118MP0003942_abnormal_urinary_system0.34222129
119MP0004811_abnormal_neuron_physiology0.33732852
120MP0002971_abnormal_brown_adipose0.33727325
121MP0001270_distended_abdomen0.33551620
122MP0009697_abnormal_copulation0.33475806
123MP0005391_vision/eye_phenotype0.33197971
124MP0003879_abnormal_hair_cell0.33021272
125MP0006036_abnormal_mitochondrial_physio0.32759103
126MP0001764_abnormal_homeostasis0.31782588
127MP0002229_neurodegeneration0.30727636
128MP0001486_abnormal_startle_reflex0.30554713
129MP0002092_abnormal_eye_morphology0.30354770
130MP0006035_abnormal_mitochondrial_morpho0.27835663
131MP0000427_abnormal_hair_cycle0.27626893
132MP0005253_abnormal_eye_physiology0.27373447
133MP0001919_abnormal_reproductive_system0.27089514
134MP0008875_abnormal_xenobiotic_pharmacok0.26706125
135MP0009250_abnormal_appendicular_skeleto0.26016596
136MP0003115_abnormal_respiratory_system0.25498572
137MP0004019_abnormal_vitamin_homeostasis0.25454105
138MP0004133_heterotaxia0.25228511
139MP0008057_abnormal_DNA_replication0.24021263
140MP0002734_abnormal_mechanical_nocicepti0.23782572
141MP0002009_preneoplasia0.23457046
142MP0002084_abnormal_developmental_patter0.22457089
143MP0005187_abnormal_penis_morphology0.22162150
144MP0003633_abnormal_nervous_system0.21672929
145MP0002109_abnormal_limb_morphology0.20784547
146MP0002405_respiratory_system_inflammati0.19304103
147MP0000778_abnormal_nervous_system0.19121449
148MP0003936_abnormal_reproductive_system0.19090987
149MP0003943_abnormal_hepatobiliary_system0.18912053
150MP0000534_abnormal_ureter_morphology0.18232749
151MP0005365_abnormal_bile_salt0.18171898
152MP0002169_no_abnormal_phenotype0.18146231
153MP0003786_premature_aging0.18097180
154MP0002873_normal_phenotype0.17912652

Predicted human phenotypes

RankGene SetZ-score
1Thyroid-stimulating hormone excess (HP:0002925)9.67607018
2Abnormal respiratory motile cilium physiology (HP:0012261)9.41455277
3Abnormal respiratory motile cilium morphology (HP:0005938)9.37929069
4Abnormal respiratory epithelium morphology (HP:0012253)9.37929069
5Abnormal ciliary motility (HP:0012262)7.94766646
6Rhinitis (HP:0012384)7.80620126
7Volvulus (HP:0002580)7.62451615
8Chronic bronchitis (HP:0004469)7.02913606
9Nasal polyposis (HP:0100582)5.58139281
10Infertility (HP:0000789)5.43730455
11Intestinal atresia (HP:0011100)5.07352815
12Pancreatic islet-cell hyperplasia (HP:0004510)4.67778366
13Bronchiectasis (HP:0002110)4.65329537
14Abnormality of the nasal mucosa (HP:0000433)4.56356814
15Nephronophthisis (HP:0000090)4.33026179
16Attenuation of retinal blood vessels (HP:0007843)4.28848616
17Abnormality of the aortic arch (HP:0012303)4.28299500
18Bronchitis (HP:0012387)4.12642854
19Severe visual impairment (HP:0001141)3.91309100
20Large for gestational age (HP:0001520)3.85991147
21Medial flaring of the eyebrow (HP:0010747)3.80083742
22Thickened helices (HP:0000391)3.75083465
23Bony spicule pigmentary retinopathy (HP:0007737)3.71421251
24Cone-rod dystrophy (HP:0000548)3.63717253
25Molar tooth sign on MRI (HP:0002419)3.62311670
26Abnormality of midbrain morphology (HP:0002418)3.62311670
27Male infertility (HP:0003251)3.54447085
28Mesangial abnormality (HP:0001966)3.54316408
29Gaze-evoked nystagmus (HP:0000640)3.53548152
30Broad alveolar ridges (HP:0000187)3.52460767
31Recurrent sinusitis (HP:0011108)3.43324667
32Abnormality of the renal medulla (HP:0100957)3.42924054
33Abnormality of the ileum (HP:0001549)3.20632529
34Congenital primary aphakia (HP:0007707)3.19112075
35Gait imbalance (HP:0002141)3.17523295
36Truncal obesity (HP:0001956)3.11385997
37Tubulointerstitial nephritis (HP:0001970)3.10905016
38Recurrent otitis media (HP:0000403)3.09821267
39Abnormality of endocrine pancreas physiology (HP:0012093)3.05857727
40Abnormality of the pancreatic islet cells (HP:0006476)3.05857727
41Oligodontia (HP:0000677)2.95405955
42Chromosomal breakage induced by crosslinking agents (HP:0003221)2.93836851
43Chromsome breakage (HP:0040012)2.90358271
44Nephrogenic diabetes insipidus (HP:0009806)2.89526859
45Poor head control (HP:0002421)2.88307217
46Gastrointestinal atresia (HP:0002589)2.78342005
47Congenital stationary night blindness (HP:0007642)2.73250663
48Type II lissencephaly (HP:0007260)2.71168805
49Abnormal spermatogenesis (HP:0008669)2.70297183
50Cerebellar dysplasia (HP:0007033)2.69827101
51Optic nerve hypoplasia (HP:0000609)2.69772627
52Amelogenesis imperfecta (HP:0000705)2.68989036
53Horizontal nystagmus (HP:0000666)2.67832929
54Nephroblastoma (Wilms tumor) (HP:0002667)2.62131934
55Congenital ichthyosiform erythroderma (HP:0007431)2.53703068
56Embryonal renal neoplasm (HP:0011794)2.52079069
57Agitation (HP:0000713)2.50381384
58Scotoma (HP:0000575)2.47114452
59Poor coordination (HP:0002370)2.45676345
60Retinal dysplasia (HP:0007973)2.44974277
61Pendular nystagmus (HP:0012043)2.43938454
62Focal motor seizures (HP:0011153)2.41847302
63Chronic sinusitis (HP:0011109)2.41496362
64Vaginal atresia (HP:0000148)2.40958856
65Genital tract atresia (HP:0001827)2.36699028
66Pili torti (HP:0003777)2.36203274
67Abnormal rod and cone electroretinograms (HP:0008323)2.34826488
68Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.34384399
69Abnormality of dental color (HP:0011073)2.32603900
70Menstrual irregularities (HP:0000858)2.32289255
71Tubulointerstitial abnormality (HP:0001969)2.29434123
72Tubular atrophy (HP:0000092)2.28317158
73Oligodactyly (hands) (HP:0001180)2.28266628
74Tented upper lip vermilion (HP:0010804)2.26341563
75Postaxial hand polydactyly (HP:0001162)2.25309123
76Aplasia/Hypoplasia of the lens (HP:0008063)2.24829937
77Pancreatic fibrosis (HP:0100732)2.19534497
78Hypoproteinemia (HP:0003075)2.19215254
79Recurrent bronchitis (HP:0002837)2.19129019
80Postaxial foot polydactyly (HP:0001830)2.18758752
81Hyperpituitarism (HP:0010514)2.16767071
82Impulsivity (HP:0100710)2.16754129
83Polyuria (HP:0000103)2.15094510
84Hyperkalemia (HP:0002153)2.13053714
85Non-midline cleft lip (HP:0100335)2.12112400
86Facial hemangioma (HP:0000329)2.08468385
87Chronic hepatic failure (HP:0100626)2.03297043
88Abnormality of the dental root (HP:0006486)2.02666913
89Taurodontia (HP:0000679)2.02666913
90Abnormality of permanent molar morphology (HP:0011071)2.02666913
91True hermaphroditism (HP:0010459)2.02017427
92Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8409906
93Absent/shortened dynein arms (HP:0200106)11.9508221
94Dynein arm defect of respiratory motile cilia (HP:0012255)11.9508221
95Azoospermia (HP:0000027)1.99884206
96Supernumerary spleens (HP:0009799)1.99725661
97Poikiloderma (HP:0001029)1.99682133
98Congenital hepatic fibrosis (HP:0002612)1.97868069
99Abnormality of dentin (HP:0010299)1.97035921
100Photophobia (HP:0000613)1.96269490
101Aplasia/Hypoplasia of the earlobes (HP:0009906)1.95168516
102Stage 5 chronic kidney disease (HP:0003774)1.94602755
103Bile duct proliferation (HP:0001408)1.94582312
104Abnormal biliary tract physiology (HP:0012439)1.94582312
105Hypophosphatemic rickets (HP:0004912)1.94164396
106Abnormality of molar (HP:0011077)1.89796206
107Abnormality of molar morphology (HP:0011070)1.89796206
108Facial cleft (HP:0002006)1.89322314
109Macular degeneration (HP:0000608)1.88722725
110Gonadotropin excess (HP:0000837)1.87469970
111Bifid tongue (HP:0010297)1.87004651
112Ectropion (HP:0000656)1.86385659
113Cystic liver disease (HP:0006706)1.86238408
114Aplasia/Hypoplasia of the tongue (HP:0010295)1.86227219
115Abnormality of the dental pulp (HP:0006479)1.85063399
116Large eyes (HP:0001090)1.84399459
117Oculomotor apraxia (HP:0000657)1.83368943
118Obsessive-compulsive behavior (HP:0000722)1.81845275
119Decreased electroretinogram (ERG) amplitude (HP:0000654)1.81289582
120Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.80801810
121Abnormal albumin level (HP:0012116)1.80629146
122Hypoalbuminemia (HP:0003073)1.80629146
123Fair hair (HP:0002286)1.78560288
124Poor speech (HP:0002465)1.78189832
125Abnormality of macular pigmentation (HP:0008002)1.77631535
126Postural instability (HP:0002172)1.76002322
127Duodenal stenosis (HP:0100867)1.74854047
128Small intestinal stenosis (HP:0012848)1.74854047
129Pancreatic cysts (HP:0001737)1.74161314
130Median cleft lip (HP:0000161)1.73306749
131Central scotoma (HP:0000603)1.73094027
132Abnormal drinking behavior (HP:0030082)1.73020553
133Polydipsia (HP:0001959)1.73020553
134Aplasia/Hypoplasia of the brainstem (HP:0007362)1.72862814
135Hypoplasia of the brainstem (HP:0002365)1.72862814
136Lissencephaly (HP:0001339)1.72286589
137Abnormality of the renal cortex (HP:0011035)1.69834069
138Abnormality of renal excretion (HP:0011036)1.69800079
139Heterotopia (HP:0002282)1.65536246
140Occipital encephalocele (HP:0002085)1.65052150
141Papillary thyroid carcinoma (HP:0002895)1.63866182
142Microglossia (HP:0000171)1.60940287
143Dyschromatopsia (HP:0007641)1.60621029
144Tubulointerstitial fibrosis (HP:0005576)1.54022702
145Tongue fasciculations (HP:0001308)1.49512346
146Broad foot (HP:0001769)1.46844499
147Decreased central vision (HP:0007663)1.43837760
148Abnormal gallbladder physiology (HP:0012438)1.41641851
149Cholecystitis (HP:0001082)1.41641851
150Anosmia (HP:0000458)1.41206247
151Decreased testicular size (HP:0008734)1.40193570
152Short ribs (HP:0000773)1.37918608
153Bell-shaped thorax (HP:0001591)1.36332532
154Renal dysplasia (HP:0000110)1.35294931
155Muscle fibrillation (HP:0010546)1.34823632
156Retinitis pigmentosa (HP:0000510)1.33851360
157Renovascular hypertension (HP:0100817)1.33415902
158Abnormal urine output (HP:0012590)1.33358531
159Type 2 muscle fiber atrophy (HP:0003554)1.32739606
160Constricted visual fields (HP:0001133)1.32734949
161Absent eyebrow (HP:0002223)1.32521174
162Short nail (HP:0001799)1.31699491
163Short thorax (HP:0010306)1.29272768
164Polycystic ovaries (HP:0000147)1.28850455
165Hypoplasia of the capital femoral epiphysis (HP:0003090)1.28224839
166Spastic tetraparesis (HP:0001285)1.27583184
167Astigmatism (HP:0000483)1.27545272
168Aganglionic megacolon (HP:0002251)1.27231062
169Retrobulbar optic neuritis (HP:0100654)1.24645815
170Optic neuritis (HP:0100653)1.24645815

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.49142193
2PDK48.49142193
3ADRBK27.46843034
4PDK25.45649848
5FRK4.62077253
6TESK14.09272267
7PRKD33.87916389
8ICK3.36044197
9ERN12.62187444
10MAPK152.10778855
11INSRR2.06106280
12WNK41.95049844
13PHKG21.93778401
14PHKG11.93778401
15BRD41.90356459
16STK391.90031854
17ADRBK11.83703504
18PTK2B1.70659798
19PNCK1.68579619
20PIK3CG1.63965568
21IRAK31.60345386
22TRIM281.54994085
23NEK21.48998181
24PLK41.48457528
25ACVR1B1.46011080
26BMPR1B1.42477352
27STK381.37479746
28EEF2K1.37191484
29MAP4K21.24344915
30DYRK1B1.22564625
31MAPK111.14839669
32DYRK31.12717083
33OXSR11.09805862
34STK38L1.07885469
35DDR21.04511853
36LMTK21.02042784
37PRKCE1.01852121
38IRAK10.94620235
39BRSK10.92522409
40CDK120.90644434
41CHEK20.88193045
42PDK10.87410589
43CAMK1G0.85367797
44MAPKAPK30.82300570
45MUSK0.81974090
46ZAK0.79930660
47TTK0.77157756
48CAMK10.76255878
49NEK90.73823145
50GRK10.72930324
51NEK60.72771550
52TGFBR10.72226646
53TYRO30.68606272
54EIF2AK30.67269361
55MAP2K60.67019904
56SGK10.64712125
57NUAK10.63413040
58STK30.63001489
59MKNK20.61197053
60CDC70.59696730
61CCNB10.59671400
62BRAF0.58899165
63RIPK10.58788741
64MAP3K60.58545442
65CAMK40.57802970
66MET0.56337163
67MAPK10.53421286
68PRKCI0.52051031
69WNK10.51351536
70WEE10.48335870
71ERBB30.48242334
72ARAF0.48013413
73SIK20.46675022
74LATS10.45257233
75CDK10.45076527
76AKT30.44438404
77PINK10.42752040
78MAPKAPK50.42469373
79MAP2K20.42003380
80NTRK20.41900411
81CDK30.41560725
82CHEK10.41551339
83MKNK10.39481892
84PASK0.39203754
85CDK20.38964775
86MAP2K70.37105310
87GRK70.35229192
88PDPK10.34339326
89DYRK1A0.34094821
90MST1R0.33613531
91ATM0.32379606
92MAP3K130.31404701
93MARK20.30832486
94PRKCB0.30588823
95CSNK1E0.30315893
96PAK10.29666064
97PRKAA10.29629976
98MAP3K40.29299911
99SIK30.28629341
100PRKCG0.28044554
101ATR0.27327420
102TRPM70.27252050
103ERBB20.27160058
104YES10.26443612
105PLK10.25684524
106MAPK140.25576518
107AKT10.25463733
108CDK90.25109725
109BMPR20.24918139
110TLK10.24795035
111STK240.24547597
112MAPK130.24109836
113CDK190.23193180
114CAMK2D0.23166488
115RPS6KA30.23164484
116PRKACB0.22739822
117MELK0.21867862
118CDK70.20870094
119TEC0.19474274
120MAP3K100.18992749
121IRAK20.17593480
122PKN10.17123908
123CAMK2G0.17059944
124WNK30.15995365
125RPS6KB10.15714579
126NLK0.14950411
127PRKG10.14287538
128TRIB30.13364329
129CAMK1D0.13270473
130MTOR0.13014399
131PRKCZ0.12604969
132SRPK10.11826008
133TESK20.11608417
134CAMK2B0.10764650
135CAMK2A0.10423240
136PRKCQ0.09634648
137STK110.09542736
138BRSK20.08551636
139PRKG20.08034848
140GRK50.07569279
141CDK60.07330158
142CSNK2A10.07202542
143CSNK1D0.05686397
144MAP3K20.05681585
145ILK0.05617577
146MARK30.05491533
147PRKAA20.05104934
148MAP3K50.04890630
149GSK3B0.04854683
150PAK30.04432512
151CAMKK10.04316553
152CDK40.04223518
153PLK20.03977314
154RPS6KA20.03816483
155AURKA0.03796924

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047405.68959964
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.56291888
3Fatty acid biosynthesis_Homo sapiens_hsa000613.49300084
4Pyruvate metabolism_Homo sapiens_hsa006203.43609618
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.38939451
6Basal transcription factors_Homo sapiens_hsa030223.16010847
7Vitamin B6 metabolism_Homo sapiens_hsa007502.95918511
8Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.93995622
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.90169166
10Propanoate metabolism_Homo sapiens_hsa006402.79157380
11Glucagon signaling pathway_Homo sapiens_hsa049222.60264791
12Butanoate metabolism_Homo sapiens_hsa006502.16215032
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.13957811
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.13851812
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.07737600
16Linoleic acid metabolism_Homo sapiens_hsa005912.00891841
17Oocyte meiosis_Homo sapiens_hsa041141.96399732
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.94006667
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.90887186
20Homologous recombination_Homo sapiens_hsa034401.84871662
21Glycosaminoglycan degradation_Homo sapiens_hsa005311.82250770
22Fanconi anemia pathway_Homo sapiens_hsa034601.81653057
23Selenocompound metabolism_Homo sapiens_hsa004501.70597722
24Carbohydrate digestion and absorption_Homo sapiens_hsa049731.66982613
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.62534657
26Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.55871982
27Cyanoamino acid metabolism_Homo sapiens_hsa004601.44828963
28PPAR signaling pathway_Homo sapiens_hsa033201.44472716
29Dorso-ventral axis formation_Homo sapiens_hsa043201.44447441
30Glycerolipid metabolism_Homo sapiens_hsa005611.43809126
31Huntingtons disease_Homo sapiens_hsa050161.42474480
32Taste transduction_Homo sapiens_hsa047421.41501334
33Sulfur relay system_Homo sapiens_hsa041221.40731719
34Pentose phosphate pathway_Homo sapiens_hsa000301.40676526
35Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.38687126
36Purine metabolism_Homo sapiens_hsa002301.38126779
37Mineral absorption_Homo sapiens_hsa049781.33096740
38Amphetamine addiction_Homo sapiens_hsa050311.31306736
39Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.30408157
40Ether lipid metabolism_Homo sapiens_hsa005651.22980490
41Insulin secretion_Homo sapiens_hsa049111.19694697
42Glycerophospholipid metabolism_Homo sapiens_hsa005641.15907962
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.10967261
44Renin secretion_Homo sapiens_hsa049241.09280211
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08217735
46Phototransduction_Homo sapiens_hsa047441.04557178
47Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.03287561
48Retinol metabolism_Homo sapiens_hsa008301.00112762
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97773198
50mRNA surveillance pathway_Homo sapiens_hsa030150.97420987
51Carbon metabolism_Homo sapiens_hsa012000.96521452
52Collecting duct acid secretion_Homo sapiens_hsa049660.95701062
53Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.95096826
54Cardiac muscle contraction_Homo sapiens_hsa042600.94091122
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91956988
56Tryptophan metabolism_Homo sapiens_hsa003800.88177575
57Ovarian steroidogenesis_Homo sapiens_hsa049130.87675594
58Arachidonic acid metabolism_Homo sapiens_hsa005900.87010726
59Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.86067540
60cAMP signaling pathway_Homo sapiens_hsa040240.86044450
61Circadian entrainment_Homo sapiens_hsa047130.82986604
62Thyroid hormone synthesis_Homo sapiens_hsa049180.82928364
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82825202
64Calcium signaling pathway_Homo sapiens_hsa040200.82752305
65Bile secretion_Homo sapiens_hsa049760.82387142
66Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81710880
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.80931644
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80665527
69Fatty acid degradation_Homo sapiens_hsa000710.80587183
70RNA transport_Homo sapiens_hsa030130.80364347
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.79388067
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78643576
73Nitrogen metabolism_Homo sapiens_hsa009100.78600330
74Fructose and mannose metabolism_Homo sapiens_hsa000510.75150222
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74060997
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73372735
77Estrogen signaling pathway_Homo sapiens_hsa049150.72439996
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72398264
79N-Glycan biosynthesis_Homo sapiens_hsa005100.72106051
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.70313848
81Circadian rhythm_Homo sapiens_hsa047100.69132378
82Gastric acid secretion_Homo sapiens_hsa049710.68834770
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68018542
84Inositol phosphate metabolism_Homo sapiens_hsa005620.66600039
85Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65187420
86ABC transporters_Homo sapiens_hsa020100.63882563
87Complement and coagulation cascades_Homo sapiens_hsa046100.62419653
88Glutathione metabolism_Homo sapiens_hsa004800.60540594
89Serotonergic synapse_Homo sapiens_hsa047260.58272678
90Salivary secretion_Homo sapiens_hsa049700.58073951
91Systemic lupus erythematosus_Homo sapiens_hsa053220.57272869
92Chemical carcinogenesis_Homo sapiens_hsa052040.56242769
93Synaptic vesicle cycle_Homo sapiens_hsa047210.54896838
94Lysine degradation_Homo sapiens_hsa003100.54163482
95Sphingolipid metabolism_Homo sapiens_hsa006000.53600314
96beta-Alanine metabolism_Homo sapiens_hsa004100.52363633
97Alcoholism_Homo sapiens_hsa050340.52094692
98Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50120280
99Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48873236
100Fatty acid metabolism_Homo sapiens_hsa012120.48816113
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47890736
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47344703
103RNA polymerase_Homo sapiens_hsa030200.46502391
104Glutamatergic synapse_Homo sapiens_hsa047240.44954041
105Dopaminergic synapse_Homo sapiens_hsa047280.43704923
106Long-term potentiation_Homo sapiens_hsa047200.42852606
107Nucleotide excision repair_Homo sapiens_hsa034200.41441098
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.40821319
109Metabolic pathways_Homo sapiens_hsa011000.40786524
110Biosynthesis of amino acids_Homo sapiens_hsa012300.40440190
111Morphine addiction_Homo sapiens_hsa050320.39615371
112Starch and sucrose metabolism_Homo sapiens_hsa005000.39476671
113Nicotine addiction_Homo sapiens_hsa050330.39169218
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38622544
115Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38385834
116Pancreatic secretion_Homo sapiens_hsa049720.38263085
117Cell cycle_Homo sapiens_hsa041100.37626578
118Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36325964
119Non-homologous end-joining_Homo sapiens_hsa034500.35673442
120RNA degradation_Homo sapiens_hsa030180.35149233
121Legionellosis_Homo sapiens_hsa051340.34272040
122Arginine biosynthesis_Homo sapiens_hsa002200.33480660
123Fat digestion and absorption_Homo sapiens_hsa049750.33176310
124Arginine and proline metabolism_Homo sapiens_hsa003300.31747521
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.31652934
126Other glycan degradation_Homo sapiens_hsa005110.30942906
127Histidine metabolism_Homo sapiens_hsa003400.30540747
128Hedgehog signaling pathway_Homo sapiens_hsa043400.30115802
129Type II diabetes mellitus_Homo sapiens_hsa049300.29773262
130Protein digestion and absorption_Homo sapiens_hsa049740.29147777
131Vascular smooth muscle contraction_Homo sapiens_hsa042700.28982570
132Sphingolipid signaling pathway_Homo sapiens_hsa040710.27892953
133MAPK signaling pathway_Homo sapiens_hsa040100.27826480
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.27758416
135Renin-angiotensin system_Homo sapiens_hsa046140.26026200
136Graft-versus-host disease_Homo sapiens_hsa053320.25850960
137Peroxisome_Homo sapiens_hsa041460.24649450
138MicroRNAs in cancer_Homo sapiens_hsa052060.24472265
139Base excision repair_Homo sapiens_hsa034100.24382845
140Type I diabetes mellitus_Homo sapiens_hsa049400.24014604
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23776386
142AMPK signaling pathway_Homo sapiens_hsa041520.23563283
143Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.21860542

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »