FAM217B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.81747397
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.75764684
3synaptic vesicle exocytosis (GO:0016079)5.58941330
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.57815705
5neuronal action potential propagation (GO:0019227)5.36092612
6vocalization behavior (GO:0071625)5.30979326
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.23111222
8regulation of synaptic vesicle exocytosis (GO:2000300)5.17706911
9glutamate secretion (GO:0014047)5.13617077
10locomotory exploration behavior (GO:0035641)5.07103771
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.99228085
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.92924413
13regulation of glutamate receptor signaling pathway (GO:1900449)4.87374530
14protein localization to synapse (GO:0035418)4.87067492
15neuron cell-cell adhesion (GO:0007158)4.71948337
16regulation of synaptic vesicle transport (GO:1902803)4.68530301
17pyrimidine nucleobase catabolic process (GO:0006208)4.59595618
18ionotropic glutamate receptor signaling pathway (GO:0035235)4.54362198
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.46770570
20regulation of long-term neuronal synaptic plasticity (GO:0048169)4.33698911
21exploration behavior (GO:0035640)4.25501855
22neurotransmitter secretion (GO:0007269)4.24235547
23regulation of neuronal synaptic plasticity (GO:0048168)4.16908736
24dendritic spine morphogenesis (GO:0060997)4.16383458
25glutamate receptor signaling pathway (GO:0007215)4.11654623
26neurotransmitter-gated ion channel clustering (GO:0072578)4.00880232
27regulation of synapse structural plasticity (GO:0051823)3.98609597
28synaptic transmission, glutamatergic (GO:0035249)3.92600537
29layer formation in cerebral cortex (GO:0021819)3.89560920
30long-term memory (GO:0007616)3.88568178
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.87999014
32positive regulation of membrane potential (GO:0045838)3.86585777
33neuron-neuron synaptic transmission (GO:0007270)3.83695932
34postsynaptic membrane organization (GO:0001941)3.81722040
35regulation of excitatory postsynaptic membrane potential (GO:0060079)3.80173934
36proline transport (GO:0015824)3.76140686
37DNA double-strand break processing (GO:0000729)3.71804870
38cerebral cortex radially oriented cell migration (GO:0021799)3.65733972
39regulation of postsynaptic membrane potential (GO:0060078)3.64468642
40positive regulation of neurotransmitter secretion (GO:0001956)3.63135522
41nucleobase catabolic process (GO:0046113)3.62800790
42presynaptic membrane assembly (GO:0097105)3.62756858
43G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.59043080
44positive regulation of neurotransmitter transport (GO:0051590)3.53934562
45gamma-aminobutyric acid transport (GO:0015812)3.49905284
46activation of protein kinase A activity (GO:0034199)3.49071526
47neurotransmitter transport (GO:0006836)3.47633615
48negative regulation of synaptic transmission, GABAergic (GO:0032229)3.45604450
49positive regulation of synapse maturation (GO:0090129)3.43576855
50regulation of neurotransmitter secretion (GO:0046928)3.42665343
51positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.42555518
52regulation of dendritic spine morphogenesis (GO:0061001)3.42337492
53regulation of synaptic plasticity (GO:0048167)3.42320007
54neuron recognition (GO:0008038)3.37621656
55gamma-aminobutyric acid signaling pathway (GO:0007214)3.36339407
56regulation of vesicle fusion (GO:0031338)3.35976829
57cellular potassium ion homeostasis (GO:0030007)3.32562092
58positive regulation of synaptic transmission, GABAergic (GO:0032230)3.29297845
59long-term synaptic potentiation (GO:0060291)3.28100778
60positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.24652743
61presynaptic membrane organization (GO:0097090)3.24014181
62synaptic vesicle endocytosis (GO:0048488)3.22970383
63regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.22712025
64regulation of neurotransmitter levels (GO:0001505)3.22348958
65regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.21893949
66response to histamine (GO:0034776)3.19677906
67cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.19278875
68regulation of synaptic transmission, glutamatergic (GO:0051966)3.18068103
69regulation of neurotransmitter transport (GO:0051588)3.17413642
70regulation of voltage-gated calcium channel activity (GO:1901385)3.16437388
71membrane depolarization (GO:0051899)3.15853824
72neuromuscular process controlling posture (GO:0050884)3.14028747
73regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.12602077
74regulation of dendritic spine development (GO:0060998)3.11649522
75positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.09000515
76auditory behavior (GO:0031223)3.07818771
77membrane depolarization during action potential (GO:0086010)3.05481273
78dendritic spine organization (GO:0097061)3.05192170
79learning (GO:0007612)3.03252776
80positive regulation of dendritic spine development (GO:0060999)3.01959394
81detection of calcium ion (GO:0005513)3.01381807
82glycosphingolipid biosynthetic process (GO:0006688)3.00808267
83regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.99910830
84cerebellar Purkinje cell differentiation (GO:0021702)2.98326506
85response to auditory stimulus (GO:0010996)2.98315771
86regulation of protein kinase A signaling (GO:0010738)2.98312509
87axonal fasciculation (GO:0007413)2.95662053
88mechanosensory behavior (GO:0007638)2.95202716
89neuromuscular process controlling balance (GO:0050885)2.94181650
90positive regulation of synaptic transmission (GO:0050806)2.92505902
91negative regulation of dendrite morphogenesis (GO:0050774)2.90970814
92cell communication by electrical coupling (GO:0010644)2.90662043
93regulation of synaptic transmission (GO:0050804)2.87183463
94synaptic transmission (GO:0007268)2.87063075
95behavioral response to cocaine (GO:0048148)2.85894630
96DNA damage response, detection of DNA damage (GO:0042769)2.85363996
97synapse assembly (GO:0007416)2.85209209
98membrane hyperpolarization (GO:0060081)2.84690015
99regulation of respiratory system process (GO:0044065)2.84435089
100C4-dicarboxylate transport (GO:0015740)2.84144968
101G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.83673550
102neuronal ion channel clustering (GO:0045161)2.83555514
103behavioral fear response (GO:0001662)2.83296978
104behavioral defense response (GO:0002209)2.83296978
105positive regulation of dendritic spine morphogenesis (GO:0061003)2.82925317
106negative regulation of DNA-dependent DNA replication (GO:2000104)2.81977993
107establishment of synaptic vesicle localization (GO:0097480)2.80979493
108synaptic vesicle transport (GO:0048489)2.80979493
109regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.79535885
110transmission of nerve impulse (GO:0019226)2.77302720
111positive regulation of potassium ion transmembrane transport (GO:1901381)2.74055587
112negative regulation of neurotransmitter transport (GO:0051589)2.69712971
113negative regulation of DNA recombination (GO:0045910)2.69221593
114cell migration in hindbrain (GO:0021535)2.67086715
115neurotransmitter uptake (GO:0001504)2.65355491
116limb bud formation (GO:0060174)2.63648182
117establishment of mitochondrion localization (GO:0051654)2.61142564
118behavioral response to nicotine (GO:0035095)2.55252176
119serotonin metabolic process (GO:0042428)2.55245484
120microtubule depolymerization (GO:0007019)2.54814721
121L-fucose catabolic process (GO:0042355)2.51347642
122fucose catabolic process (GO:0019317)2.51347642
123L-fucose metabolic process (GO:0042354)2.51347642
124histone H4-K12 acetylation (GO:0043983)2.49490194
125central nervous system projection neuron axonogenesis (GO:0021952)2.48525723
126fear response (GO:0042596)2.48312358
127negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.47902213
128protein polyglutamylation (GO:0018095)2.44905110
129neuromuscular synaptic transmission (GO:0007274)2.44812084
130regulation of collateral sprouting (GO:0048670)2.44287461
131fatty acid elongation (GO:0030497)2.41910061
132regulation of DNA endoreduplication (GO:0032875)2.41487652
133hippocampus development (GO:0021766)2.40521807
134negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.38146230
135negative regulation of translation, ncRNA-mediated (GO:0040033)2.38146230
136regulation of translation, ncRNA-mediated (GO:0045974)2.38146230
137somatic hypermutation of immunoglobulin genes (GO:0016446)2.37571569
138somatic diversification of immune receptors via somatic mutation (GO:0002566)2.37571569
139RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.37537545
140neuronal action potential (GO:0019228)2.34595107
141atrial cardiac muscle cell action potential (GO:0086014)2.34221726
142histone H2A acetylation (GO:0043968)2.32449054
143olfactory bulb development (GO:0021772)2.31434764
144regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29167589
145regulation of telomere maintenance (GO:0032204)2.28727213
146synapse organization (GO:0050808)2.28706607

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.56697241
2GBX2_23144817_ChIP-Seq_PC3_Human3.71694475
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.25564180
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.25132689
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.07378081
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.80941651
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.80941651
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.77163260
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.72081698
10REST_21632747_ChIP-Seq_MESCs_Mouse2.71252575
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.67029201
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.61744050
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.56889437
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.54620454
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.54610165
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.54587630
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.52586554
18DROSHA_22980978_ChIP-Seq_HELA_Human2.36249146
19IKZF1_21737484_ChIP-ChIP_HCT116_Human2.31972553
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27236765
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.25288781
22TAF15_26573619_Chip-Seq_HEK293_Human2.24989619
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.21209448
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.20407014
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.17091812
26EWS_26573619_Chip-Seq_HEK293_Human2.02138297
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.99388321
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.98031954
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.97281942
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.91297720
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.90845536
32KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.88102981
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82033377
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.81250405
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78638388
36SMAD_19615063_ChIP-ChIP_OVARY_Human1.74898747
37SMAD4_21799915_ChIP-Seq_A2780_Human1.72031187
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.68908699
39NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.62845866
40EST1_17652178_ChIP-ChIP_JURKAT_Human1.61381924
41IGF1R_20145208_ChIP-Seq_DFB_Human1.60674372
42MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60603285
43AR_21572438_ChIP-Seq_LNCaP_Human1.59434665
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.56992918
45P300_19829295_ChIP-Seq_ESCs_Human1.50129090
46SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49934250
47GABP_17652178_ChIP-ChIP_JURKAT_Human1.47930111
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47295786
49ZNF274_21170338_ChIP-Seq_K562_Hela1.46635016
50PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46488769
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.44901023
52CBP_20019798_ChIP-Seq_JUKART_Human1.37515924
53IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37515924
54ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.37392013
55NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36608230
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36018593
57ERG_21242973_ChIP-ChIP_JURKAT_Human1.33815560
58EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31983567
59GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.31931745
60AR_25329375_ChIP-Seq_VCAP_Human1.31600013
61PCGF2_27294783_Chip-Seq_ESCs_Mouse1.31035901
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.29126709
63ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.28387861
64E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27912104
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.27870754
66POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27034160
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27034160
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26803094
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26641713
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.26064322
71CBX2_27304074_Chip-Seq_ESCs_Mouse1.26050309
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26011860
73RING1B_27294783_Chip-Seq_ESCs_Mouse1.25888311
74E2F4_17652178_ChIP-ChIP_JURKAT_Human1.24248821
75ELK1_19687146_ChIP-ChIP_HELA_Human1.22718851
76TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.22661101
77FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.21026686
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.20252843
79KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.19292333
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.18957900
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18419288
82P53_22387025_ChIP-Seq_ESCs_Mouse1.18089550
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17203469
84TP53_22573176_ChIP-Seq_HFKS_Human1.15590285
85RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.14267540
86MYC_18940864_ChIP-ChIP_HL60_Human1.14252508
87RNF2_27304074_Chip-Seq_NSC_Mouse1.14195780
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13381388
89VDR_23849224_ChIP-Seq_CD4+_Human1.12861812
90SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12621814
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11067737
92YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.10807450
93POU3F2_20337985_ChIP-ChIP_501MEL_Human1.10790508
94STAT3_23295773_ChIP-Seq_U87_Human1.10391187
95TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10163368
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09679579
97P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09230890
98EZH2_27294783_Chip-Seq_NPCs_Mouse1.08887145
99FLI1_21867929_ChIP-Seq_TH2_Mouse1.08330227
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08313506
101FUS_26573619_Chip-Seq_HEK293_Human1.07579940
102PIAS1_25552417_ChIP-Seq_VCAP_Human1.06739859
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06275204
104WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06028260
105AR_19668381_ChIP-Seq_PC3_Human1.05773709
106SOX9_26525672_Chip-Seq_HEART_Mouse1.04960199
107CMYC_18555785_Chip-Seq_ESCs_Mouse1.03761545
108NFE2_27457419_Chip-Seq_LIVER_Mouse1.03734848
109SUZ12_18555785_Chip-Seq_ESCs_Mouse1.03633737
110DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03506102
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03444005
112E2F1_18555785_Chip-Seq_ESCs_Mouse1.03408424
113IRF1_19129219_ChIP-ChIP_H3396_Human1.02950637
114TCF4_23295773_ChIP-Seq_U87_Human1.02214299
115TCF4_22108803_ChIP-Seq_LS180_Human1.01952987
116TP53_16413492_ChIP-PET_HCT116_Human1.01531925
117RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01066569
118PRDM14_20953172_ChIP-Seq_ESCs_Human0.99979468
119BCAT_22108803_ChIP-Seq_LS180_Human0.99376676
120RUNX2_22187159_ChIP-Seq_PCA_Human0.99192618
121YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98250154
122RING1B_27294783_Chip-Seq_NPCs_Mouse0.98195404
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98072310
124WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97557043
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97382180
126TAL1_26923725_Chip-Seq_HPCs_Mouse0.96671873
127P300_18555785_Chip-Seq_ESCs_Mouse0.96073237
128AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94577987
129UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93710609
130ARNT_22903824_ChIP-Seq_MCF-7_Human0.92196880
131RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.91731399
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.91349343
133JUN_21703547_ChIP-Seq_K562_Human0.91121663
134EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.90177525
135KDM2B_26808549_Chip-Seq_K562_Human0.90132506
136ER_23166858_ChIP-Seq_MCF-7_Human0.89263126
137CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87913532
138ZNF217_24962896_ChIP-Seq_MCF-7_Human0.87324865
139TP53_18474530_ChIP-ChIP_U2OS_Human0.86972377
140TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.86268231
141AHR_22903824_ChIP-Seq_MCF-7_Human0.85918303
142NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85860805
143VDR_22108803_ChIP-Seq_LS180_Human0.85174225
144TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.85097087
145CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.84987381
146SMAD3_21741376_ChIP-Seq_HESCs_Human0.83849340
147NANOG_18555785_Chip-Seq_ESCs_Mouse0.81813977
148GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81509686

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.13935671
2MP0003880_abnormal_central_pattern5.59893137
3MP0003635_abnormal_synaptic_transmissio4.10365484
4MP0004270_analgesia3.34126643
5MP0001968_abnormal_touch/_nociception3.32699286
6MP0009745_abnormal_behavioral_response3.30886837
7MP0002063_abnormal_learning/memory/cond3.13091411
8MP0002064_seizures3.11625063
9MP0009046_muscle_twitch3.06997340
10MP0008877_abnormal_DNA_methylation2.77708635
11MP0002572_abnormal_emotion/affect_behav2.68434751
12MP0002272_abnormal_nervous_system2.59041504
13MP0005423_abnormal_somatic_nervous2.54625348
14MP0002736_abnormal_nociception_after2.53687166
15MP0001486_abnormal_startle_reflex2.48797499
16MP0002734_abnormal_mechanical_nocicepti2.46529904
17MP0001501_abnormal_sleep_pattern2.44561474
18MP0002735_abnormal_chemical_nociception2.20294314
19MP0002822_catalepsy2.09085448
20MP0002733_abnormal_thermal_nociception2.05522817
21MP0002067_abnormal_sensory_capabilities2.04054030
22MP0001970_abnormal_pain_threshold2.00408486
23MP0001188_hyperpigmentation1.89393383
24MP0003879_abnormal_hair_cell1.89375273
25MP0008569_lethality_at_weaning1.85293200
26MP0006276_abnormal_autonomic_nervous1.80825744
27MP0001440_abnormal_grooming_behavior1.76621658
28MP0005646_abnormal_pituitary_gland1.73944820
29MP0002102_abnormal_ear_morphology1.73584901
30MP0004811_abnormal_neuron_physiology1.70725283
31MP0003121_genomic_imprinting1.70630112
32MP0002184_abnormal_innervation1.70416084
33MP0002909_abnormal_adrenal_gland1.68759693
34MP0002557_abnormal_social/conspecific_i1.65320499
35MP0005386_behavior/neurological_phenoty1.61916215
36MP0004924_abnormal_behavior1.61916215
37MP0009780_abnormal_chondrocyte_physiolo1.61226555
38MP0000751_myopathy1.60718320
39MP0002837_dystrophic_cardiac_calcinosis1.58553362
40MP0004858_abnormal_nervous_system1.50896008
41MP0008058_abnormal_DNA_repair1.49709221
42MP0000778_abnormal_nervous_system1.45911812
43MP0001905_abnormal_dopamine_level1.38612787
44MP0000955_abnormal_spinal_cord1.38076620
45MP0001984_abnormal_olfaction1.34975696
46MP0003329_amyloid_beta_deposits1.34435924
47MP0003633_abnormal_nervous_system1.34425997
48MP0002066_abnormal_motor_capabilities/c1.29126857
49MP0004142_abnormal_muscle_tone1.27372408
50MP0002234_abnormal_pharynx_morphology1.24001450
51MP0005409_darkened_coat_color1.23091446
52MP0002882_abnormal_neuron_morphology1.22766423
53MP0008789_abnormal_olfactory_epithelium1.17631996
54MP0010094_abnormal_chromosome_stability1.17061423
55MP0001529_abnormal_vocalization1.16373533
56MP0001502_abnormal_circadian_rhythm1.15545195
57MP0003122_maternal_imprinting1.14819772
58MP0001485_abnormal_pinna_reflex1.14030829
59MP0004215_abnormal_myocardial_fiber1.12735864
60MP0004145_abnormal_muscle_electrophysio1.12688451
61MP0008057_abnormal_DNA_replication1.12144084
62MP0000013_abnormal_adipose_tissue1.11764639
63MP0005394_taste/olfaction_phenotype1.11126223
64MP0005499_abnormal_olfactory_system1.11126223
65MP0005645_abnormal_hypothalamus_physiol1.08450305
66MP0005253_abnormal_eye_physiology1.06973949
67MP0004484_altered_response_of1.06065757
68MP0005535_abnormal_body_temperature1.05447965
69MP0005075_abnormal_melanosome_morpholog1.04492145
70MP0000372_irregular_coat_pigmentation1.02902613
71MP0002751_abnormal_autonomic_nervous1.01591216
72MP0003631_nervous_system_phenotype1.00107161
73MP0004085_abnormal_heartbeat1.00003975
74MP0010386_abnormal_urinary_bladder0.99113030
75MP0003646_muscle_fatigue0.97494395
76MP0004510_myositis0.95170818
77MP0003075_altered_response_to0.94414715
78MP0004742_abnormal_vestibular_system0.93941610
79MP0008874_decreased_physiological_sensi0.93308265
80MP0003787_abnormal_imprinting0.92867910
81MP0002638_abnormal_pupillary_reflex0.91613641
82MP0008872_abnormal_physiological_respon0.91474181
83MP0002152_abnormal_brain_morphology0.90965601
84MP0002938_white_spotting0.88348853
85MP0003123_paternal_imprinting0.87445032
86MP0002229_neurodegeneration0.86129901
87MP0001346_abnormal_lacrimal_gland0.85497462
88MP0005167_abnormal_blood-brain_barrier0.85250066
89MP0004043_abnormal_pH_regulation0.84554069
90MP0003861_abnormal_nervous_system0.84496202
91MP0004133_heterotaxia0.83099518
92MP0003938_abnormal_ear_development0.82470042
93MP0006292_abnormal_olfactory_placode0.81105779
94MP0004885_abnormal_endolymph0.79456465
95MP0004147_increased_porphyrin_level0.78028997
96MP0001963_abnormal_hearing_physiology0.77439912
97MP0003698_abnormal_male_reproductive0.75935872
98MP0005551_abnormal_eye_electrophysiolog0.75815486
99MP0003567_abnormal_fetal_cardiomyocyte0.75728756
100MP0000631_abnormal_neuroendocrine_gland0.75463699
101MP0005187_abnormal_penis_morphology0.73975169
102MP0003119_abnormal_digestive_system0.72803762
103MP0002069_abnormal_eating/drinking_beha0.72715570
104MP0002009_preneoplasia0.71604226
105MP0001664_abnormal_digestion0.71491786
106MP0006035_abnormal_mitochondrial_morpho0.69696052
107MP0001986_abnormal_taste_sensitivity0.69565005
108MP0003634_abnormal_glial_cell0.69031143
109MP0003172_abnormal_lysosome_physiology0.68953644
110MP0002876_abnormal_thyroid_physiology0.68866328
111MP0001177_atelectasis0.68708681
112MP0001293_anophthalmia0.68451721
113MP0002653_abnormal_ependyma_morphology0.67804368
114MP0005084_abnormal_gallbladder_morpholo0.67786440
115MP0002233_abnormal_nose_morphology0.67582832
116MP0000516_abnormal_urinary_system0.66755382
117MP0005367_renal/urinary_system_phenotyp0.66755382
118MP0002090_abnormal_vision0.66421086
119MP0000569_abnormal_digit_pigmentation0.66355416
120MP0000015_abnormal_ear_pigmentation0.66041594
121MP0006036_abnormal_mitochondrial_physio0.65884412
122MP0000749_muscle_degeneration0.65542673
123MP0003303_peritoneal_inflammation0.65527086
124MP0003137_abnormal_impulse_conducting0.64936547
125MP0000427_abnormal_hair_cycle0.64582024
126MP0002752_abnormal_somatic_nervous0.62503620
127MP0004233_abnormal_muscle_weight0.60928946
128MP0000920_abnormal_myelination0.60743004
129MP0004130_abnormal_muscle_cell0.60631921
130MP0005174_abnormal_tail_pigmentation0.59476381
131MP0006072_abnormal_retinal_apoptosis0.59414394
132MP0004036_abnormal_muscle_relaxation0.58405207
133MP0005623_abnormal_meninges_morphology0.57461530
134MP0003690_abnormal_glial_cell0.56253352
135MP0002972_abnormal_cardiac_muscle0.53979925
136MP0009379_abnormal_foot_pigmentation0.52063841
137MP0000747_muscle_weakness0.51787005

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.22500698
2Myokymia (HP:0002411)5.96735688
3Visual hallucinations (HP:0002367)5.92379435
4Focal seizures (HP:0007359)5.71697976
5Epileptic encephalopathy (HP:0200134)4.90281987
6Atonic seizures (HP:0010819)4.83660711
7Febrile seizures (HP:0002373)4.61839874
8Absence seizures (HP:0002121)4.33423123
9Generalized tonic-clonic seizures (HP:0002069)3.94857016
10Progressive cerebellar ataxia (HP:0002073)3.92793011
11Dialeptic seizures (HP:0011146)3.92030149
12Broad-based gait (HP:0002136)3.73765008
13Progressive inability to walk (HP:0002505)3.62502228
14Mutism (HP:0002300)3.57360195
15Abnormality of the labia minora (HP:0012880)3.57275706
16Poor eye contact (HP:0000817)3.50050277
17Gaze-evoked nystagmus (HP:0000640)3.47096289
18Hyperventilation (HP:0002883)3.46401445
19Action tremor (HP:0002345)3.44228571
20Papilledema (HP:0001085)3.42131607
21Depression (HP:0000716)3.33094827
22Anxiety (HP:0000739)3.25645002
23Amblyopia (HP:0000646)3.12754188
24Truncal ataxia (HP:0002078)3.09190466
25Supranuclear gaze palsy (HP:0000605)3.06063169
26Impaired social interactions (HP:0000735)2.98251591
27Abnormal social behavior (HP:0012433)2.98251591
28Limb dystonia (HP:0002451)2.92611708
29Dysdiadochokinesis (HP:0002075)2.92585234
30Inability to walk (HP:0002540)2.85595573
31Agitation (HP:0000713)2.83338629
32Ankle clonus (HP:0011448)2.81271737
33Abnormal eating behavior (HP:0100738)2.71671273
34Stereotypic behavior (HP:0000733)2.70570526
35Urinary bladder sphincter dysfunction (HP:0002839)2.66404396
36Drooling (HP:0002307)2.66317228
37Excessive salivation (HP:0003781)2.66317228
38Postural instability (HP:0002172)2.65552822
39Impaired vibration sensation in the lower limbs (HP:0002166)2.64665052
40Dysmetria (HP:0001310)2.61410733
41Pheochromocytoma (HP:0002666)2.56054368
42Genetic anticipation (HP:0003743)2.54445789
43Impaired smooth pursuit (HP:0007772)2.52010316
44Lissencephaly (HP:0001339)2.46235922
45Gait imbalance (HP:0002141)2.45600795
46Bradykinesia (HP:0002067)2.44439129
47Hypothermia (HP:0002045)2.40009163
48Ventricular fibrillation (HP:0001663)2.38829677
49Medial flaring of the eyebrow (HP:0010747)2.38116276
50Absent speech (HP:0001344)2.34999650
51Hemiparesis (HP:0001269)2.34767311
52Neuroendocrine neoplasm (HP:0100634)2.34128940
53Diplopia (HP:0000651)2.31291605
54Abnormality of binocular vision (HP:0011514)2.31291605
55Torticollis (HP:0000473)2.30519903
56Inappropriate behavior (HP:0000719)2.30124499
57Urinary urgency (HP:0000012)2.24964773
58Scanning speech (HP:0002168)2.24280954
59Volvulus (HP:0002580)2.22517539
60Hemiplegia (HP:0002301)2.20600451
61Failure to thrive in infancy (HP:0001531)2.18436009
62Nephrogenic diabetes insipidus (HP:0009806)2.17872663
63Focal dystonia (HP:0004373)2.17684135
64Congenital primary aphakia (HP:0007707)2.15405296
65True hermaphroditism (HP:0010459)2.13402128
66Generalized myoclonic seizures (HP:0002123)2.12350780
67Status epilepticus (HP:0002133)2.12244678
68Abnormality of the metopic suture (HP:0005556)2.10659094
69Epileptiform EEG discharges (HP:0011182)2.10192492
70Abnormality of ocular smooth pursuit (HP:0000617)2.10184484
71Psychosis (HP:0000709)2.09845654
72Pancreatic cysts (HP:0001737)2.07768158
73Obstructive sleep apnea (HP:0002870)2.06172923
74Progressive microcephaly (HP:0000253)2.05806603
75Abnormality of the corticospinal tract (HP:0002492)2.05806456
76Rapidly progressive (HP:0003678)2.05566328
77Hypoventilation (HP:0002791)2.04194434
78Glioma (HP:0009733)2.03877906
79Methylmalonic acidemia (HP:0002912)2.03053374
80Polyphagia (HP:0002591)2.02243149
81Muscular hypotonia of the trunk (HP:0008936)2.02204682
82Pachygyria (HP:0001302)2.01354864
83Abnormal EKG (HP:0003115)2.01279923
84Pancreatic fibrosis (HP:0100732)2.00832581
85Genital tract atresia (HP:0001827)2.00713728
86Aplasia/Hypoplasia of the sternum (HP:0006714)2.00041224
87Medulloblastoma (HP:0002885)1.99060118
88Cerebral hypomyelination (HP:0006808)1.98879153
89Molar tooth sign on MRI (HP:0002419)1.97490762
90Abnormality of midbrain morphology (HP:0002418)1.97490762
91EEG with generalized epileptiform discharges (HP:0011198)1.97209991
92Neoplasm of the adrenal cortex (HP:0100641)1.95895009
93Nephronophthisis (HP:0000090)1.95574093
94Fetal akinesia sequence (HP:0001989)1.94810517
95Colon cancer (HP:0003003)1.94555591
96Nonprogressive disorder (HP:0003680)1.94086684
97Annular pancreas (HP:0001734)1.93924890
98Craniofacial dystonia (HP:0012179)1.92813661
99Vaginal atresia (HP:0000148)1.92037365
100Spinal canal stenosis (HP:0003416)1.90991375
101Protruding tongue (HP:0010808)1.88254078
102Lower limb asymmetry (HP:0100559)1.88162330
103Spastic gait (HP:0002064)1.87500043
104Neuronal loss in central nervous system (HP:0002529)1.87326348
105Hyperthyroidism (HP:0000836)1.86951456
106Dysmetric saccades (HP:0000641)1.86512909
107Gait ataxia (HP:0002066)1.85848677
108Morphological abnormality of the pyramidal tract (HP:0002062)1.85299367
109Dyskinesia (HP:0100660)1.84956469
110Neoplasm of the oral cavity (HP:0100649)1.84519101
111Exercise-induced muscle cramps (HP:0003710)1.84138100
112Abnormality of the astrocytes (HP:0100707)1.83839605
113Astrocytoma (HP:0009592)1.83839605
114Apathy (HP:0000741)1.83407298
115Neoplasm of the peripheral nervous system (HP:0100007)1.83322850
116Abnormality of alanine metabolism (HP:0010916)1.82500590
117Hyperalaninemia (HP:0003348)1.82500590
118Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82500590
119Ependymoma (HP:0002888)1.81987910
120Hypsarrhythmia (HP:0002521)1.80940570
121Lower limb amyotrophy (HP:0007210)1.80521418
122Megalencephaly (HP:0001355)1.79734562
123Insidious onset (HP:0003587)1.79704349
124Termporal pattern (HP:0011008)1.79704349
125Abnormality of salivation (HP:0100755)1.79242894
126Lower limb muscle weakness (HP:0007340)1.78230077
127Intention tremor (HP:0002080)1.77601894
128Amyotrophic lateral sclerosis (HP:0007354)1.77406101
129Bradycardia (HP:0001662)1.75924305
130Degeneration of the lateral corticospinal tracts (HP:0002314)1.75537720
131Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.75537720
132Primary atrial arrhythmia (HP:0001692)1.75476951
133Absent/shortened dynein arms (HP:0200106)1.74872284
134Dynein arm defect of respiratory motile cilia (HP:0012255)1.74872284
135Impaired vibratory sensation (HP:0002495)1.74526277
136Blue irides (HP:0000635)1.74423091
137Poor suck (HP:0002033)1.74113681
138Type II lissencephaly (HP:0007260)1.73509915
139Diminished motivation (HP:0000745)1.72845738
140Gastroesophageal reflux (HP:0002020)1.72362778
141Incomplete penetrance (HP:0003829)1.72271061
142Retinal dysplasia (HP:0007973)1.72075184
143Specific learning disability (HP:0001328)1.72035187
144Prominent metopic ridge (HP:0005487)1.69679484
145Cortical dysplasia (HP:0002539)1.69593980
146CNS hypomyelination (HP:0003429)1.68946695
147Hyperglycinemia (HP:0002154)1.68541371
148Poor coordination (HP:0002370)1.68298031
149Aplasia/Hypoplasia of the uvula (HP:0010293)1.67871168
150Neoplasm of the adrenal gland (HP:0100631)1.66531835
151Postaxial hand polydactyly (HP:0001162)1.66035722
152Hepatoblastoma (HP:0002884)1.63501343
153Abnormality of chromosome stability (HP:0003220)1.63359402
154Stomach cancer (HP:0012126)1.61932872
155Muscle hypertrophy of the lower extremities (HP:0008968)1.60700073
156Meckel diverticulum (HP:0002245)1.57954965
157Postaxial foot polydactyly (HP:0001830)1.56559249
158Abnormality of the ileum (HP:0001549)1.55556970

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.23557349
2EPHA44.00011654
3MAP3K93.60542876
4MAP3K123.19078284
5RIPK43.18869366
6TRIM283.17508579
7MAP2K72.91849602
8MAP4K22.85896950
9MAP3K42.80611718
10CASK2.78514476
11MINK12.74555431
12TNIK2.42887068
13WNK32.27103118
14DAPK22.18066999
15MARK12.12625965
16BCR2.10874528
17MAP2K42.09092195
18CDK191.98579032
19NTRK11.98396663
20FRK1.95620569
21KSR21.95255858
22FES1.86664540
23TSSK61.82670241
24CAMKK11.80414686
25NTRK21.72215633
26CAMKK21.70077514
27GRK51.65309055
28BMPR1B1.61597839
29DAPK11.60526164
30PAK61.57196755
31ARAF1.56593653
32KSR11.55853032
33PRKD31.52235372
34ERBB31.51964111
35MUSK1.49030227
36PLK21.47724419
37SIK21.38031386
38CDK51.37884139
39SRPK11.35682327
40CAMK11.29491614
41CSNK1G31.28586821
42PRPF4B1.28352909
43MKNK21.27554324
44WEE11.25627159
45NUAK11.20816259
46MAP3K131.16907572
47MAPK131.14359037
48DYRK21.12876543
49CSNK1G11.11848523
50MAP3K21.09876287
51OBSCN1.05969521
52AKT31.03383744
53ZAK1.03096300
54TAF11.03075752
55CSNK1A1L1.02396447
56PLK31.02355474
57CCNB11.00595929
58PTK2B1.00216730
59RAF10.98510962
60CAMK2A0.97882156
61STK380.97453280
62PRKCG0.96617231
63BUB10.96537610
64PHKG20.96369010
65PHKG10.96369010
66STK110.89229197
67RET0.86826547
68BMPR20.85732728
69UHMK10.81477445
70MAP3K10.80682298
71RPS6KA40.79565327
72PNCK0.79218032
73CDC70.78421740
74LMTK20.76861148
75PDK10.76718527
76MKNK10.76149452
77FGFR20.76099931
78CDK30.74427281
79MAP3K60.71529956
80PAK30.68433013
81CDK140.67915465
82BRD40.67708441
83SGK20.67645190
84FGR0.67264176
85PLK40.66790036
86CDK180.66471853
87DYRK30.66339903
88PRKCH0.65987175
89PDPK10.65512944
90CSNK1G20.64166475
91TNK20.63079405
92PLK10.62216863
93CDK150.61742297
94SGK4940.60674662
95SGK2230.60674662
96SCYL20.60445540
97PINK10.59370068
98SIK30.59006799
99CAMK40.56688684
100GRK70.56612422
101IRAK10.56397404
102VRK10.56358413
103CAMK2B0.56012186
104TAOK10.55926710
105SGK10.55380121
106ACVR1B0.54591203
107CDK11A0.54345876
108EPHA30.53274928
109ATR0.53127990
110TYRO30.50970689
111EIF2AK30.50103567
112NEK10.49606624
113CSNK1D0.49504469
114EIF2AK20.49473511
115MAP3K70.48682514
116EIF2AK10.48680779
117BRSK20.48372464
118CAMK2D0.48034430
119YES10.47904208
120DAPK30.47874295
121DYRK1A0.47793797
122SGK30.47469175
123MARK20.47314633
124CSNK1E0.46800190
125DMPK0.46541155
126MAPKAPK50.45247156
127CAMK2G0.44520379
128BRAF0.44219203
129BRSK10.42312832
130PRKCE0.42007864
131TAOK30.41688635
132FYN0.40987856
133CSNK1A10.40954550
134MYLK0.38023261
135OXSR10.36429839
136MAP3K50.36367583
137MAP2K60.35906660
138MAPK120.35679150
139RPS6KA30.35632186
140ALK0.35356578
141LATS20.34636699
142RPS6KA20.33840049
143RIPK10.32734486
144PRKCZ0.32473833
145ADRBK10.32405090
146MAP2K10.31282693
147TAOK20.30050682
148SYK0.29418472

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.50951281
2Synaptic vesicle cycle_Homo sapiens_hsa047213.28162118
3Olfactory transduction_Homo sapiens_hsa047402.69832770
4Circadian entrainment_Homo sapiens_hsa047132.63707273
5Long-term potentiation_Homo sapiens_hsa047202.61658325
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.61519649
7GABAergic synapse_Homo sapiens_hsa047272.45486164
8Morphine addiction_Homo sapiens_hsa050322.42480118
9Glutamatergic synapse_Homo sapiens_hsa047242.40313513
10Amphetamine addiction_Homo sapiens_hsa050312.36149187
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.34470514
12Dopaminergic synapse_Homo sapiens_hsa047282.14550042
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.13212164
14Salivary secretion_Homo sapiens_hsa049702.07480802
15Non-homologous end-joining_Homo sapiens_hsa034502.03406040
16Regulation of autophagy_Homo sapiens_hsa041401.86695554
17Cholinergic synapse_Homo sapiens_hsa047251.85796830
18Insulin secretion_Homo sapiens_hsa049111.85515060
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.83730875
20Gastric acid secretion_Homo sapiens_hsa049711.83684929
21Protein export_Homo sapiens_hsa030601.81869039
22Basal transcription factors_Homo sapiens_hsa030221.81059307
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78180212
24Renin secretion_Homo sapiens_hsa049241.75387325
25Serotonergic synapse_Homo sapiens_hsa047261.70467470
26Long-term depression_Homo sapiens_hsa047301.68198523
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68014635
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.66944726
29Taste transduction_Homo sapiens_hsa047421.66231462
30Oxytocin signaling pathway_Homo sapiens_hsa049211.65680960
31Calcium signaling pathway_Homo sapiens_hsa040201.65463431
32RNA degradation_Homo sapiens_hsa030181.63675052
33Propanoate metabolism_Homo sapiens_hsa006401.63265632
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.54647115
35Collecting duct acid secretion_Homo sapiens_hsa049661.51815039
36Cocaine addiction_Homo sapiens_hsa050301.51510763
37Butanoate metabolism_Homo sapiens_hsa006501.50011869
38GnRH signaling pathway_Homo sapiens_hsa049121.48903749
39Fanconi anemia pathway_Homo sapiens_hsa034601.43576867
40Cardiac muscle contraction_Homo sapiens_hsa042601.38151588
41Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.37801685
42Mismatch repair_Homo sapiens_hsa034301.34190563
43Gap junction_Homo sapiens_hsa045401.30975893
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.30000408
45cAMP signaling pathway_Homo sapiens_hsa040241.29074885
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.28063165
47Homologous recombination_Homo sapiens_hsa034401.23756430
48RNA polymerase_Homo sapiens_hsa030201.19640960
49Glioma_Homo sapiens_hsa052141.14169669
50Estrogen signaling pathway_Homo sapiens_hsa049151.13116408
51Steroid biosynthesis_Homo sapiens_hsa001001.12349101
52Vibrio cholerae infection_Homo sapiens_hsa051101.09710260
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.09244947
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08834349
55Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07732487
56cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06416773
57Spliceosome_Homo sapiens_hsa030401.04889049
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.04047445
59Type II diabetes mellitus_Homo sapiens_hsa049301.03103373
60ErbB signaling pathway_Homo sapiens_hsa040121.02750623
61Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.02637345
62mRNA surveillance pathway_Homo sapiens_hsa030151.01191968
63Proteasome_Homo sapiens_hsa030501.00590019
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98827047
65Melanogenesis_Homo sapiens_hsa049160.97518145
66Alzheimers disease_Homo sapiens_hsa050100.94921261
67Oxidative phosphorylation_Homo sapiens_hsa001900.93204751
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.92136663
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92116060
70Fatty acid elongation_Homo sapiens_hsa000620.91550460
71RNA transport_Homo sapiens_hsa030130.90301877
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89341425
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88549873
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.84978523
75Parkinsons disease_Homo sapiens_hsa050120.84859271
76Dorso-ventral axis formation_Homo sapiens_hsa043200.83009987
77Oocyte meiosis_Homo sapiens_hsa041140.82625517
78Dilated cardiomyopathy_Homo sapiens_hsa054140.82253958
79Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80936053
80Phototransduction_Homo sapiens_hsa047440.80575883
81Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.80548465
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.79999825
83Axon guidance_Homo sapiens_hsa043600.79265375
84Nucleotide excision repair_Homo sapiens_hsa034200.77613311
85Pancreatic secretion_Homo sapiens_hsa049720.75722289
86beta-Alanine metabolism_Homo sapiens_hsa004100.74328202
87MAPK signaling pathway_Homo sapiens_hsa040100.72533583
88DNA replication_Homo sapiens_hsa030300.71965822
89Selenocompound metabolism_Homo sapiens_hsa004500.70659418
90Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70369620
91Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69314382
92Base excision repair_Homo sapiens_hsa034100.68329017
93VEGF signaling pathway_Homo sapiens_hsa043700.67347838
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63601093
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63068435
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61980883
97Choline metabolism in cancer_Homo sapiens_hsa052310.61772917
98Purine metabolism_Homo sapiens_hsa002300.61177035
99Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60692552
100Thyroid hormone synthesis_Homo sapiens_hsa049180.60034517
101Glucagon signaling pathway_Homo sapiens_hsa049220.58866434
102Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.58562437
103Ras signaling pathway_Homo sapiens_hsa040140.58331993
104Cell cycle_Homo sapiens_hsa041100.57841558
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.57204020
106Type I diabetes mellitus_Homo sapiens_hsa049400.56092878
107Rap1 signaling pathway_Homo sapiens_hsa040150.54853690
108Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.54836224
109Ether lipid metabolism_Homo sapiens_hsa005650.54812946
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54476475
111Vitamin B6 metabolism_Homo sapiens_hsa007500.54302018
112Inositol phosphate metabolism_Homo sapiens_hsa005620.53845276
113Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52167788
114African trypanosomiasis_Homo sapiens_hsa051430.51924644
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.51158166
116Nitrogen metabolism_Homo sapiens_hsa009100.50697084
117Non-small cell lung cancer_Homo sapiens_hsa052230.50392189
118Huntingtons disease_Homo sapiens_hsa050160.50363640
119Chemokine signaling pathway_Homo sapiens_hsa040620.50343369
120Alcoholism_Homo sapiens_hsa050340.49076416
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47367425
122Insulin signaling pathway_Homo sapiens_hsa049100.46937740
123SNARE interactions in vesicular transport_Homo sapiens_hsa041300.46827841
124Platelet activation_Homo sapiens_hsa046110.45908537
125Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.45319603
126Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.44602778
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44148299
128Endocytosis_Homo sapiens_hsa041440.43512057
129Circadian rhythm_Homo sapiens_hsa047100.42127977
130Rheumatoid arthritis_Homo sapiens_hsa053230.40975810
131Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40827429
132Peroxisome_Homo sapiens_hsa041460.40736057
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.40558324
134Pyrimidine metabolism_Homo sapiens_hsa002400.40429076
135mTOR signaling pathway_Homo sapiens_hsa041500.40226966
136Renal cell carcinoma_Homo sapiens_hsa052110.39564572
1372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.37567457
138Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37146879
139Fatty acid metabolism_Homo sapiens_hsa012120.36316440
140Prolactin signaling pathway_Homo sapiens_hsa049170.34997534
141Wnt signaling pathway_Homo sapiens_hsa043100.33875914
142Endometrial cancer_Homo sapiens_hsa052130.33159351
143B cell receptor signaling pathway_Homo sapiens_hsa046620.32253647
144Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.26220279
145AMPK signaling pathway_Homo sapiens_hsa041520.25921996

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