FAM234B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.02139952
2synaptic vesicle maturation (GO:0016188)5.97697386
3locomotory exploration behavior (GO:0035641)5.41939267
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.36862470
5glutamate secretion (GO:0014047)5.30813612
6synaptic vesicle exocytosis (GO:0016079)5.28187947
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.23195709
8vocalization behavior (GO:0071625)5.09385586
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.00762931
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.84563652
11regulation of synaptic vesicle exocytosis (GO:2000300)4.80602486
12DNA double-strand break processing (GO:0000729)4.69011895
13regulation of glutamate receptor signaling pathway (GO:1900449)4.66219159
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.53451933
15regulation of neuronal synaptic plasticity (GO:0048168)4.48607377
16neurotransmitter-gated ion channel clustering (GO:0072578)4.47396089
17neuronal action potential propagation (GO:0019227)4.47156006
18protein localization to synapse (GO:0035418)4.43539648
19neurotransmitter secretion (GO:0007269)4.41882985
20neuron cell-cell adhesion (GO:0007158)4.29261863
21regulation of synaptic vesicle transport (GO:1902803)4.28504005
22regulation of long-term neuronal synaptic plasticity (GO:0048169)4.28453801
23exploration behavior (GO:0035640)4.26050621
24gamma-aminobutyric acid transport (GO:0015812)4.20985262
25regulation of synapse structural plasticity (GO:0051823)4.11581752
26synaptic transmission, glutamatergic (GO:0035249)4.10403031
27cellular potassium ion homeostasis (GO:0030007)4.00794429
28layer formation in cerebral cortex (GO:0021819)3.99009843
29glutamate receptor signaling pathway (GO:0007215)3.96569436
30dendritic spine morphogenesis (GO:0060997)3.94746255
31neuron-neuron synaptic transmission (GO:0007270)3.86332561
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.79080589
33regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.78086531
34neuromuscular process controlling posture (GO:0050884)3.76451780
35proline transport (GO:0015824)3.76430645
36sodium ion export (GO:0071436)3.76232254
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.70907326
38long-term memory (GO:0007616)3.68747421
39neuromuscular process controlling balance (GO:0050885)3.57957943
40neurotransmitter transport (GO:0006836)3.57380020
41C4-dicarboxylate transport (GO:0015740)3.57257205
42positive regulation of membrane potential (GO:0045838)3.57244751
43regulation of synaptic plasticity (GO:0048167)3.53872735
44regulation of postsynaptic membrane potential (GO:0060078)3.52088420
45transmission of nerve impulse (GO:0019226)3.50984851
46synaptic vesicle endocytosis (GO:0048488)3.48139193
47water-soluble vitamin biosynthetic process (GO:0042364)3.47597824
48regulation of dendritic spine morphogenesis (GO:0061001)3.47574919
49negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.47274249
50positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.46010670
51regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.43379283
52cerebellar Purkinje cell differentiation (GO:0021702)3.39119609
53regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.38378907
54auditory behavior (GO:0031223)3.37218243
55regulation of neurotransmitter levels (GO:0001505)3.36798487
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.36347711
57positive regulation of synapse maturation (GO:0090129)3.36019713
58glycine transport (GO:0015816)3.35233723
59long-term synaptic potentiation (GO:0060291)3.34974151
60response to auditory stimulus (GO:0010996)3.34182862
61neuron recognition (GO:0008038)3.32719164
62activation of protein kinase A activity (GO:0034199)3.31454355
63dendrite morphogenesis (GO:0048813)3.26634334
64detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26548069
65regulation of neurotransmitter secretion (GO:0046928)3.23090861
66negative regulation of synaptic transmission, GABAergic (GO:0032229)3.22960864
67positive regulation of synaptic transmission, GABAergic (GO:0032230)3.22072544
68gamma-aminobutyric acid signaling pathway (GO:0007214)3.19285959
69retinal cone cell development (GO:0046549)3.18964153
70L-amino acid import (GO:0043092)3.18822783
71positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.13327659
72response to pheromone (GO:0019236)3.12799291
73neuronal ion channel clustering (GO:0045161)3.11007314
74membrane hyperpolarization (GO:0060081)3.10062003
75positive regulation of neurotransmitter transport (GO:0051590)3.09777617
76positive regulation of neurotransmitter secretion (GO:0001956)3.09763965
77axonal fasciculation (GO:0007413)3.07575651
78neuromuscular process (GO:0050905)3.07106430
79cell communication by electrical coupling (GO:0010644)3.06667014
80cerebellar granule cell differentiation (GO:0021707)3.05592179
81cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.05424541
82regulation of neurotransmitter transport (GO:0051588)3.03458943
83membrane depolarization (GO:0051899)3.00683186
84limb bud formation (GO:0060174)2.99576796
85adult walking behavior (GO:0007628)2.99394195
86positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.99226764
87G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.97922741
88presynaptic membrane assembly (GO:0097105)2.97744910
89postsynaptic membrane organization (GO:0001941)2.97625860
90regulation of vesicle fusion (GO:0031338)2.96293866
91prepulse inhibition (GO:0060134)2.96145157
92regulation of respiratory system process (GO:0044065)2.95219863
93positive regulation of dendritic spine development (GO:0060999)2.95132742
94regulation of synaptic transmission (GO:0050804)2.95002756
95positive regulation of synaptic transmission (GO:0050806)2.94904162
96response to histamine (GO:0034776)2.94476222
97regulation of female receptivity (GO:0045924)2.94117373
98membrane depolarization during action potential (GO:0086010)2.93025731
99regulation of dendritic spine development (GO:0060998)2.92730931
100behavioral fear response (GO:0001662)2.92310017
101behavioral defense response (GO:0002209)2.92310017
102G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.90916123
103learning (GO:0007612)2.90758425
104cerebellar Purkinje cell layer development (GO:0021680)2.90630914
105presynaptic membrane organization (GO:0097090)2.89728611
106dendritic spine organization (GO:0097061)2.87746730
107negative regulation of telomere maintenance (GO:0032205)2.87042936
108cell migration in hindbrain (GO:0021535)2.85518384
109respiratory chain complex IV assembly (GO:0008535)2.83253456
110replication fork processing (GO:0031297)2.81548448
111pyrimidine nucleobase catabolic process (GO:0006208)2.75792461
112keratinocyte development (GO:0003334)2.74998343
113negative regulation of DNA-dependent DNA replication (GO:2000104)2.71249929
114regulation of telomere maintenance (GO:0032204)2.69582449
115protein polyglutamylation (GO:0018095)2.61078617
116glycosphingolipid biosynthetic process (GO:0006688)2.55984327
117nucleobase catabolic process (GO:0046113)2.54940891
118histone H2A acetylation (GO:0043968)2.52536636
119synapsis (GO:0007129)2.50299981
120cullin deneddylation (GO:0010388)2.49863352
121lactate metabolic process (GO:0006089)2.48187214
122piRNA metabolic process (GO:0034587)2.46995872
123prostate gland growth (GO:0060736)2.45437650
124RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.44880008
125DNA catabolic process, exonucleolytic (GO:0000738)2.44236961
126startle response (GO:0001964)2.43694207
127protein complex biogenesis (GO:0070271)2.40286510
128protein localization to cilium (GO:0061512)2.38134782
129regulation of helicase activity (GO:0051095)2.36917699
130regulation of meiosis I (GO:0060631)2.36751921
131positive regulation of meiosis (GO:0045836)2.36574005
132fucose catabolic process (GO:0019317)2.36354202
133L-fucose metabolic process (GO:0042354)2.36354202
134L-fucose catabolic process (GO:0042355)2.36354202
135regulation of telomere maintenance via telomerase (GO:0032210)2.36009983
136axoneme assembly (GO:0035082)2.35903821
137protein K11-linked deubiquitination (GO:0035871)2.35741443
138behavioral response to nicotine (GO:0035095)2.35692873
139auditory receptor cell stereocilium organization (GO:0060088)2.35178242
140positive regulation of protein autophosphorylation (GO:0031954)2.34501717
141kidney morphogenesis (GO:0060993)2.33481435
142atrial cardiac muscle cell action potential (GO:0086014)2.33427572
143peptidyl-cysteine modification (GO:0018198)2.32808263
144negative regulation of transcription regulatory region DNA binding (GO:2000678)2.32323505
145reflex (GO:0060004)2.31596209
146glial cell proliferation (GO:0014009)2.29180419
147cornea development in camera-type eye (GO:0061303)2.27030223
148negative regulation of cytosolic calcium ion concentration (GO:0051481)2.26828316
149protein K6-linked ubiquitination (GO:0085020)2.26306474
150regulation of calcium ion-dependent exocytosis (GO:0017158)2.24940373
151regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.24599571
152regulation of mitotic spindle checkpoint (GO:1903504)2.24599571
153cell fate commitment involved in formation of primary germ layer (GO:0060795)2.24490207
154mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.23885292
155mitochondrial respiratory chain complex I assembly (GO:0032981)2.23885292
156NADH dehydrogenase complex assembly (GO:0010257)2.23885292
157detection of mechanical stimulus involved in sensory perception (GO:0050974)2.23546575
158synapse assembly (GO:0007416)2.21625986
159negative regulation of DNA recombination (GO:0045910)2.21391350
160mitochondrial respiratory chain complex assembly (GO:0033108)2.21370365
161inner ear receptor stereocilium organization (GO:0060122)2.21336913
162regulation of cilium movement (GO:0003352)2.21186429
163somatic diversification of immune receptors via somatic mutation (GO:0002566)2.21179263
164somatic hypermutation of immunoglobulin genes (GO:0016446)2.21179263
165cytochrome complex assembly (GO:0017004)2.20661366
166negative regulation of dendrite development (GO:2000171)2.20392824
167regulation of collateral sprouting (GO:0048670)2.20360056
168recombinational repair (GO:0000725)2.20142791
169double-strand break repair via homologous recombination (GO:0000724)2.19210936
170negative regulation of translation, ncRNA-mediated (GO:0040033)2.19120637
171regulation of translation, ncRNA-mediated (GO:0045974)2.19120637
172negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.19120637

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.49882124
2GBX2_23144817_ChIP-Seq_PC3_Human3.23866277
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10401701
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04190542
5IGF1R_20145208_ChIP-Seq_DFB_Human2.96402479
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.88799882
7REST_21632747_ChIP-Seq_MESCs_Mouse2.84550632
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.84339835
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.67904517
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.67904517
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.63110820
12VDR_22108803_ChIP-Seq_LS180_Human2.61863171
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.61225394
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.60200243
15DROSHA_22980978_ChIP-Seq_HELA_Human2.59483957
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.57888235
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.57882703
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.50181577
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.49196405
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.45475899
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.44366532
22FUS_26573619_Chip-Seq_HEK293_Human2.39189948
23EZH2_27304074_Chip-Seq_ESCs_Mouse2.37704065
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.33632775
25SALL1_21062744_ChIP-ChIP_HESCs_Human2.26838373
26EWS_26573619_Chip-Seq_HEK293_Human2.26294731
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.25994280
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.19231437
29EED_16625203_ChIP-ChIP_MESCs_Mouse2.16594574
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.15587829
31RNF2_27304074_Chip-Seq_ESCs_Mouse2.14781154
32KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.07157064
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.04622945
34CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.03729343
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.02246388
36ERG_21242973_ChIP-ChIP_JURKAT_Human1.98115357
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.98031491
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.94547986
39IKZF1_21737484_ChIP-ChIP_HCT116_Human1.93642551
40AR_21572438_ChIP-Seq_LNCaP_Human1.93051516
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.90616812
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90170444
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.85885926
44ER_23166858_ChIP-Seq_MCF-7_Human1.62484717
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59387717
46EST1_17652178_ChIP-ChIP_JURKAT_Human1.58998434
47CBP_20019798_ChIP-Seq_JUKART_Human1.56193032
48IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56193032
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54189003
50UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.51730205
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50572213
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.49980921
53DNAJC2_21179169_ChIP-ChIP_NT2_Human1.49068225
54BCAT_22108803_ChIP-Seq_LS180_Human1.48662012
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.46508063
56MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44948799
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44848243
58GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.44587011
59RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.43371171
60GABP_17652178_ChIP-ChIP_JURKAT_Human1.43073736
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.42922110
62TAF15_26573619_Chip-Seq_HEK293_Human1.39474412
63SMAD4_21799915_ChIP-Seq_A2780_Human1.38528665
64RING1B_27294783_Chip-Seq_ESCs_Mouse1.37303925
65ZNF274_21170338_ChIP-Seq_K562_Hela1.34912408
66KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34256521
67TCF4_22108803_ChIP-Seq_LS180_Human1.33640218
68PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.32880158
69MYC_18940864_ChIP-ChIP_HL60_Human1.30098521
70ELK1_19687146_ChIP-ChIP_HELA_Human1.29472287
71NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.29114474
72EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25597362
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.24281001
74RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.23802734
75FLI1_21867929_ChIP-Seq_TH2_Mouse1.23273843
76PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.23199891
77WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21434901
78KDM2B_26808549_Chip-Seq_K562_Human1.21119498
79TP53_22573176_ChIP-Seq_HFKS_Human1.21071684
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20492340
81AR_19668381_ChIP-Seq_PC3_Human1.19483527
82TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.17891718
83CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16465262
84SMAD3_21741376_ChIP-Seq_EPCs_Human1.16222345
85RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15908476
86EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.15857273
87ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.15109979
88NR3C1_23031785_ChIP-Seq_PC12_Mouse1.14723351
89RING1B_27294783_Chip-Seq_NPCs_Mouse1.14603611
90ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13826121
91SOX2_19829295_ChIP-Seq_ESCs_Human1.13274277
92NANOG_19829295_ChIP-Seq_ESCs_Human1.13274277
93PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12105580
94P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11964759
95VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10890086
96AR_25329375_ChIP-Seq_VCAP_Human1.10732338
97KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.10377675
98STAT3_23295773_ChIP-Seq_U87_Human1.10172927
99PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09459084
100P300_19829295_ChIP-Seq_ESCs_Human1.08970115
101SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07742462
102TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07525872
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07482769
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07482769
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07115297
106CBX2_27304074_Chip-Seq_ESCs_Mouse1.06926211
107IRF1_19129219_ChIP-ChIP_H3396_Human1.06621627
108FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06454119
109ZFP57_27257070_Chip-Seq_ESCs_Mouse1.06416569
110CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.05186488
111PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04680235
112OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03539308
113PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02966404
114WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01632418
115NANOG_18555785_Chip-Seq_ESCs_Mouse1.01463201
116TET1_21490601_ChIP-Seq_MESCs_Mouse1.01381778
117CTCF_27219007_Chip-Seq_Bcells_Human1.01105348
118PIAS1_25552417_ChIP-Seq_VCAP_Human0.98962572
119HTT_18923047_ChIP-ChIP_STHdh_Human0.97055911
120TCF4_23295773_ChIP-Seq_U87_Human0.96565019
121GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96026402
122E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.95942315
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95314980
124JUN_21703547_ChIP-Seq_K562_Human0.95144648
125YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94994833
126ZNF217_24962896_ChIP-Seq_MCF-7_Human0.94974609
127FOXM1_26456572_ChIP-Seq_MCF-7_Human0.94811253
128TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94054017
129NOTCH1_21737748_ChIP-Seq_TLL_Human0.93547407
130NCOR_22424771_ChIP-Seq_293T_Human0.93138535
131EZH2_27294783_Chip-Seq_NPCs_Mouse0.92798051
132ARNT_22903824_ChIP-Seq_MCF-7_Human0.92414184
133KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.92051414
134TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91591991
135RNF2_27304074_Chip-Seq_NSC_Mouse0.90772410
136RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90765863
137CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.90684264
138SUZ12_27294783_Chip-Seq_NPCs_Mouse0.90650530
139SMAD3_21741376_ChIP-Seq_ESCs_Human0.89314271
140AHR_22903824_ChIP-Seq_MCF-7_Human0.88970173
141SMAD4_21741376_ChIP-Seq_HESCs_Human0.88691363
142OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.87193093
143THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86680736
144BMI1_23680149_ChIP-Seq_NPCS_Mouse0.84508293
145ZFP281_27345836_Chip-Seq_ESCs_Mouse0.82934870
146TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82777122
147RUNX2_22187159_ChIP-Seq_PCA_Human0.82251289
148SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.80676023
149SMAD3_21741376_ChIP-Seq_HESCs_Human0.80645994
150AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.80510767
151TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.80040331
152PRDM14_20953172_ChIP-Seq_ESCs_Human0.79200258
153NR3C1_21868756_ChIP-Seq_MCF10A_Human0.78752497
154RXR_22108803_ChIP-Seq_LS180_Human0.76609206
155SMAD4_21741376_ChIP-Seq_EPCs_Human0.76324191
156KLF4_19829295_ChIP-Seq_ESCs_Human0.74787361
157TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.74029789
158TP53_20018659_ChIP-ChIP_R1E_Mouse0.73604798

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.68108844
2MP0003880_abnormal_central_pattern4.68352701
3MP0003635_abnormal_synaptic_transmissio4.14223928
4MP0004270_analgesia3.73857574
5MP0009745_abnormal_behavioral_response3.41494515
6MP0002063_abnormal_learning/memory/cond3.35374855
7MP0002064_seizures3.29418996
8MP0002822_catalepsy3.16492829
9MP0009046_muscle_twitch3.07574543
10MP0002572_abnormal_emotion/affect_behav2.84984373
11MP0001968_abnormal_touch/_nociception2.81554758
12MP0001486_abnormal_startle_reflex2.68068868
13MP0002272_abnormal_nervous_system2.67433955
14MP0008877_abnormal_DNA_methylation2.63436503
15MP0005423_abnormal_somatic_nervous2.63104829
16MP0002102_abnormal_ear_morphology2.52886684
17MP0002734_abnormal_mechanical_nocicepti2.46656448
18MP0003329_amyloid_beta_deposits2.32250708
19MP0002736_abnormal_nociception_after2.31538452
20MP0001501_abnormal_sleep_pattern2.14096290
21MP0009780_abnormal_chondrocyte_physiolo2.07779527
22MP0008569_lethality_at_weaning2.02395552
23MP0002733_abnormal_thermal_nociception2.02107629
24MP0001440_abnormal_grooming_behavior2.01754620
25MP0002735_abnormal_chemical_nociception1.94955835
26MP0001970_abnormal_pain_threshold1.92307812
27MP0002067_abnormal_sensory_capabilities1.91034142
28MP0003890_abnormal_embryonic-extraembry1.84849192
29MP0000778_abnormal_nervous_system1.83075754
30MP0004885_abnormal_endolymph1.79354545
31MP0005646_abnormal_pituitary_gland1.79312616
32MP0004811_abnormal_neuron_physiology1.77921129
33MP0002909_abnormal_adrenal_gland1.76524981
34MP0003195_calcinosis1.74312625
35MP0002557_abnormal_social/conspecific_i1.73845197
36MP0005386_behavior/neurological_phenoty1.71749806
37MP0004924_abnormal_behavior1.71749806
38MP0000955_abnormal_spinal_cord1.69293254
39MP0002184_abnormal_innervation1.67557895
40MP0004858_abnormal_nervous_system1.65542679
41MP0001529_abnormal_vocalization1.63158873
42MP0003121_genomic_imprinting1.62492796
43MP0003879_abnormal_hair_cell1.58972079
44MP0000427_abnormal_hair_cycle1.57039168
45MP0005253_abnormal_eye_physiology1.55801045
46MP0005645_abnormal_hypothalamus_physiol1.49031933
47MP0002882_abnormal_neuron_morphology1.47073329
48MP0002066_abnormal_motor_capabilities/c1.46083445
49MP0004133_heterotaxia1.45813133
50MP0003633_abnormal_nervous_system1.43944409
51MP0008057_abnormal_DNA_replication1.41905098
52MP0003011_delayed_dark_adaptation1.41532494
53MP0004142_abnormal_muscle_tone1.41480738
54MP0002837_dystrophic_cardiac_calcinosis1.41210017
55MP0001984_abnormal_olfaction1.41043822
56MP0001502_abnormal_circadian_rhythm1.40318351
57MP0008995_early_reproductive_senescence1.37540506
58MP0006292_abnormal_olfactory_placode1.36571105
59MP0003119_abnormal_digestive_system1.36184113
60MP0002751_abnormal_autonomic_nervous1.33087312
61MP0006276_abnormal_autonomic_nervous1.30367269
62MP0000647_abnormal_sebaceous_gland1.26862247
63MP0000372_irregular_coat_pigmentation1.25965893
64MP0003631_nervous_system_phenotype1.24100203
65MP0003690_abnormal_glial_cell1.23843858
66MP0008058_abnormal_DNA_repair1.22871270
67MP0002160_abnormal_reproductive_system1.21072000
68MP0000604_amyloidosis1.20470599
69MP0003787_abnormal_imprinting1.19287218
70MP0000920_abnormal_myelination1.18176800
71MP0001905_abnormal_dopamine_level1.18123375
72MP0002152_abnormal_brain_morphology1.11760219
73MP0008872_abnormal_physiological_respon1.10850054
74MP0009697_abnormal_copulation1.09334442
75MP0002638_abnormal_pupillary_reflex1.09296136
76MP0002229_neurodegeneration1.09278324
77MP0003634_abnormal_glial_cell1.07770076
78MP0010094_abnormal_chromosome_stability1.07761894
79MP0003075_altered_response_to1.05980437
80MP0003283_abnormal_digestive_organ1.05557428
81MP0005187_abnormal_penis_morphology1.04556690
82MP0003122_maternal_imprinting1.01607059
83MP0002069_abnormal_eating/drinking_beha1.01208904
84MP0002938_white_spotting1.01172674
85MP0000516_abnormal_urinary_system0.97455815
86MP0005367_renal/urinary_system_phenotyp0.97455815
87MP0003632_abnormal_nervous_system0.96335219
88MP0001485_abnormal_pinna_reflex0.95854795
89MP0005551_abnormal_eye_electrophysiolog0.95447593
90MP0008874_decreased_physiological_sensi0.94121876
91MP0008789_abnormal_olfactory_epithelium0.93548508
92MP0004215_abnormal_myocardial_fiber0.92506671
93MP0003937_abnormal_limbs/digits/tail_de0.90906277
94MP0002234_abnormal_pharynx_morphology0.89909335
95MP0002233_abnormal_nose_morphology0.89346976
96MP0003693_abnormal_embryo_hatching0.89288333
97MP0003718_maternal_effect0.87857734
98MP0003786_premature_aging0.86366424
99MP0008875_abnormal_xenobiotic_pharmacok0.86071144
100MP0008007_abnormal_cellular_replicative0.85696715
101MP0001963_abnormal_hearing_physiology0.85443906
102MP0005389_reproductive_system_phenotype0.85396421
103MP0002653_abnormal_ependyma_morphology0.85365848
104MP0001929_abnormal_gametogenesis0.84231428
105MP0004742_abnormal_vestibular_system0.83574827
106MP0000383_abnormal_hair_follicle0.81462492
107MP0003698_abnormal_male_reproductive0.81309820
108MP0001177_atelectasis0.80799835
109MP0001293_anophthalmia0.80546902
110MP0005535_abnormal_body_temperature0.79764614
111MP0001986_abnormal_taste_sensitivity0.78125787
112MP0000751_myopathy0.76639767
113MP0002282_abnormal_trachea_morphology0.76580391
114MP0008961_abnormal_basal_metabolism0.76155447
115MP0003567_abnormal_fetal_cardiomyocyte0.75614693
116MP0002752_abnormal_somatic_nervous0.74939599
117MP0000013_abnormal_adipose_tissue0.73411933
118MP0004043_abnormal_pH_regulation0.73112137
119MP0003137_abnormal_impulse_conducting0.70966077
120MP0003172_abnormal_lysosome_physiology0.70962992
121MP0004233_abnormal_muscle_weight0.70821294
122MP0001664_abnormal_digestion0.70713604
123MP0004085_abnormal_heartbeat0.70256947
124MP0000631_abnormal_neuroendocrine_gland0.68913323
125MP0002090_abnormal_vision0.68733687
126MP0005499_abnormal_olfactory_system0.66880702
127MP0005394_taste/olfaction_phenotype0.66880702
128MP0010769_abnormal_survival0.57654679
129MP0001188_hyperpigmentation0.56840551
130MP0000569_abnormal_digit_pigmentation0.56804388
131MP0004145_abnormal_muscle_electrophysio0.56603735
132MP0005171_absent_coat_pigmentation0.56136187
133MP0001943_abnormal_respiration0.55670272
134MP0010770_preweaning_lethality0.55621695
135MP0002082_postnatal_lethality0.55621695
136MP0010768_mortality/aging0.54171625
137MP0005167_abnormal_blood-brain_barrier0.54141246
138MP0003861_abnormal_nervous_system0.54106372
139MP0003956_abnormal_body_size0.53543065
140MP0002876_abnormal_thyroid_physiology0.53436129
141MP0006072_abnormal_retinal_apoptosis0.52573568
142MP0001299_abnormal_eye_distance/0.50842250
143MP0000639_abnormal_adrenal_gland0.49773828
144MP0003656_abnormal_erythrocyte_physiolo0.49129805
145MP0004147_increased_porphyrin_level0.48102974

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.40953521
2Myokymia (HP:0002411)7.32792872
3Focal seizures (HP:0007359)5.49010346
4Visual hallucinations (HP:0002367)5.02772511
5Epileptic encephalopathy (HP:0200134)4.67736630
6Atonic seizures (HP:0010819)4.50688225
7Absence seizures (HP:0002121)4.09289735
8Febrile seizures (HP:0002373)4.07382181
9Action tremor (HP:0002345)3.99192637
10Progressive cerebellar ataxia (HP:0002073)3.88507377
11Supranuclear gaze palsy (HP:0000605)3.84580915
12Ankle clonus (HP:0011448)3.81691843
13Dialeptic seizures (HP:0011146)3.74663740
14Generalized tonic-clonic seizures (HP:0002069)3.73658739
15Dysdiadochokinesis (HP:0002075)3.48717028
16Depression (HP:0000716)3.42096400
17Impaired vibration sensation in the lower limbs (HP:0002166)3.41531834
18Neurofibrillary tangles (HP:0002185)3.40401158
19Dysmetria (HP:0001310)3.39067089
20Pancreatic cysts (HP:0001737)3.34124188
21Poor eye contact (HP:0000817)3.31070105
22Anxiety (HP:0000739)3.16439688
23Gaze-evoked nystagmus (HP:0000640)3.16187011
24Intention tremor (HP:0002080)3.15792233
25Broad-based gait (HP:0002136)3.14020613
26Postural instability (HP:0002172)3.11018395
27Abnormal social behavior (HP:0012433)3.10061744
28Impaired social interactions (HP:0000735)3.10061744
29Cerebral inclusion bodies (HP:0100314)3.06552121
30Torticollis (HP:0000473)3.02468481
31Volvulus (HP:0002580)3.01926048
32Abnormal eating behavior (HP:0100738)3.01615162
33Spastic gait (HP:0002064)3.01594062
34Abnormality of the lower motor neuron (HP:0002366)3.01590798
35Hyperventilation (HP:0002883)3.00721738
36Truncal ataxia (HP:0002078)2.99571697
37Pancreatic fibrosis (HP:0100732)2.98200645
38True hermaphroditism (HP:0010459)2.96019653
39Abnormality of the labia minora (HP:0012880)2.94544046
40Urinary bladder sphincter dysfunction (HP:0002839)2.92683086
41Megalencephaly (HP:0001355)2.88225236
42Scanning speech (HP:0002168)2.86151601
43Focal dystonia (HP:0004373)2.85190579
44Urinary urgency (HP:0000012)2.84627204
45Status epilepticus (HP:0002133)2.68872304
46Pendular nystagmus (HP:0012043)2.65778819
47Mutism (HP:0002300)2.64712278
48Hemiplegia (HP:0002301)2.62751527
49Hemiparesis (HP:0001269)2.61283231
50Craniofacial dystonia (HP:0012179)2.58881786
51Pheochromocytoma (HP:0002666)2.58784639
52Epileptiform EEG discharges (HP:0011182)2.58339772
53Nephronophthisis (HP:0000090)2.57430673
54Amblyopia (HP:0000646)2.57072106
55Abnormality of the corticospinal tract (HP:0002492)2.55930945
56Diplopia (HP:0000651)2.54823297
57Abnormality of binocular vision (HP:0011514)2.54823297
58Papilledema (HP:0001085)2.54076253
59Bradykinesia (HP:0002067)2.53724284
60Impaired smooth pursuit (HP:0007772)2.52419579
61EEG with generalized epileptiform discharges (HP:0011198)2.50447000
62Annular pancreas (HP:0001734)2.49993873
63Abnormality of midbrain morphology (HP:0002418)2.47123759
64Molar tooth sign on MRI (HP:0002419)2.47123759
65Chronic hepatic failure (HP:0100626)2.44572541
66Hypsarrhythmia (HP:0002521)2.43837779
67Termporal pattern (HP:0011008)2.43291261
68Insidious onset (HP:0003587)2.43291261
69Impaired vibratory sensation (HP:0002495)2.42838360
70Aplasia/Hypoplasia of the tongue (HP:0010295)2.42546422
71Medial flaring of the eyebrow (HP:0010747)2.40784428
72Methylmalonic acidemia (HP:0002912)2.40676463
73Optic nerve hypoplasia (HP:0000609)2.40374100
74Colon cancer (HP:0003003)2.37830978
75Clonus (HP:0002169)2.34694754
76Progressive inability to walk (HP:0002505)2.33544317
77Excessive salivation (HP:0003781)2.32661197
78Drooling (HP:0002307)2.32661197
79Insomnia (HP:0100785)2.32300045
80Lower limb muscle weakness (HP:0007340)2.32257244
81Hypothermia (HP:0002045)2.30892171
82Generalized myoclonic seizures (HP:0002123)2.28410794
83Genetic anticipation (HP:0003743)2.27846225
84Ventricular fibrillation (HP:0001663)2.26367334
85Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.25325137
86Abolished electroretinogram (ERG) (HP:0000550)2.24236906
87Intestinal atresia (HP:0011100)2.23781304
88Abnormality of ocular smooth pursuit (HP:0000617)2.23766114
89Genital tract atresia (HP:0001827)2.22165640
90Stereotypic behavior (HP:0000733)2.21412574
91Ependymoma (HP:0002888)2.20210633
92Gait imbalance (HP:0002141)2.18393447
93Dysmetric saccades (HP:0000641)2.17979130
94Vaginal atresia (HP:0000148)2.15544077
95Abnormality of the renal medulla (HP:0100957)2.14662891
96Abnormality of the renal cortex (HP:0011035)2.13935120
97Neuroendocrine neoplasm (HP:0100634)2.13451824
98Polyphagia (HP:0002591)2.11206626
99Delusions (HP:0000746)2.11196031
100Limb dystonia (HP:0002451)2.10313630
101Fetal akinesia sequence (HP:0001989)2.09631709
102Neuronal loss in central nervous system (HP:0002529)2.07909319
103Glioma (HP:0009733)2.07387206
104Agitation (HP:0000713)2.05091370
105Abnormality of the astrocytes (HP:0100707)2.02610163
106Astrocytoma (HP:0009592)2.02610163
107Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.00577386
108Degeneration of the lateral corticospinal tracts (HP:0002314)2.00577386
109Rigidity (HP:0002063)1.98328440
110Septo-optic dysplasia (HP:0100842)1.98162153
111Type II lissencephaly (HP:0007260)1.97572047
112Congenital primary aphakia (HP:0007707)1.96935921
113Aplasia/Hypoplasia of the spleen (HP:0010451)1.96603185
114Akinesia (HP:0002304)1.96157651
115Gait ataxia (HP:0002066)1.95753314
116Asplenia (HP:0001746)1.95450470
117Cystic liver disease (HP:0006706)1.93935379
118Incomplete penetrance (HP:0003829)1.93889415
119Abnormality of saccadic eye movements (HP:0000570)1.93566069
120Lissencephaly (HP:0001339)1.93394328
121Sclerocornea (HP:0000647)1.92851716
122Psychosis (HP:0000709)1.92700005
123Breast carcinoma (HP:0003002)1.92405960
124Progressive macrocephaly (HP:0004481)1.91067236
125Neoplasm of the adrenal cortex (HP:0100641)1.90678581
126Concave nail (HP:0001598)1.88323680
127Specific learning disability (HP:0001328)1.88015830
128Nephrogenic diabetes insipidus (HP:0009806)1.87427193
129Thickened helices (HP:0000391)1.86913059
130Pancreatic islet-cell hyperplasia (HP:0004510)1.85852751
131Acute necrotizing encephalopathy (HP:0006965)1.84535522
132Methylmalonic aciduria (HP:0012120)1.82871261
133Absent speech (HP:0001344)1.82751221
134Aqueductal stenosis (HP:0002410)1.82715665
135Aplasia involving bones of the extremities (HP:0009825)1.80653520
136Aplasia involving bones of the upper limbs (HP:0009823)1.80653520
137Aplasia of the phalanges of the hand (HP:0009802)1.80653520
138Abnormality of the ileum (HP:0001549)1.80412415
139Congenital stationary night blindness (HP:0007642)1.79810903
140Acute encephalopathy (HP:0006846)1.79706895
141Peripheral hypomyelination (HP:0007182)1.78769111
142Clumsiness (HP:0002312)1.77048282
143Renal cortical cysts (HP:0000803)1.76738576
144Anencephaly (HP:0002323)1.76621957
145Turricephaly (HP:0000262)1.76592235
146Dandy-Walker malformation (HP:0001305)1.76012934
147Ectopic kidney (HP:0000086)1.75721281
148Resting tremor (HP:0002322)1.75686790
149Amyotrophic lateral sclerosis (HP:0007354)1.74749249
150Inability to walk (HP:0002540)1.74392543
151Aplasia/Hypoplasia of the uvula (HP:0010293)1.74351556
152Meckel diverticulum (HP:0002245)1.74190790
153Pointed chin (HP:0000307)1.74029568
154Spastic tetraparesis (HP:0001285)1.73719695
155Increased CSF lactate (HP:0002490)1.72978909
156Bifid tongue (HP:0010297)1.72130898
157Abnormality of glycolysis (HP:0004366)1.69650735
158Absent septum pellucidum (HP:0001331)1.67727660
159Abnormality of endocrine pancreas physiology (HP:0012093)1.67275825
160Abnormality of the pancreatic islet cells (HP:0006476)1.67275825
161Gastrointestinal atresia (HP:0002589)1.64937627
162Failure to thrive in infancy (HP:0001531)1.64817147
163Hypoplastic pelvis (HP:0008839)1.64242891
164Preaxial hand polydactyly (HP:0001177)1.61488251
165Mitochondrial inheritance (HP:0001427)1.61317922
166Hyperglycinemia (HP:0002154)1.61299611
167Degeneration of anterior horn cells (HP:0002398)1.61270032
168Abnormality of the anterior horn cell (HP:0006802)1.61270032
169Aplasia/Hypoplasia of the tibia (HP:0005772)1.61124121
170Pachygyria (HP:0001302)1.61118073
171Labial hypoplasia (HP:0000066)1.60911752
172Anophthalmia (HP:0000528)1.60109256
173Abnormality of macular pigmentation (HP:0008002)1.58374335

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.73339203
2NTRK33.92691864
3MAP3K93.55393563
4FRK3.26668934
5TRIM282.97380160
6WNK32.88543522
7MARK12.83014723
8DAPK22.82532022
9MAP3K42.63905385
10MAP4K22.61180564
11BMPR1B2.59468663
12MINK12.47542572
13NTRK22.35506037
14EIF2AK32.33864933
15PAK62.21947460
16MST42.20831359
17PRKD32.13428836
18MAP2K72.12114901
19MUSK2.10333134
20FER2.09147961
21MKNK22.08034222
22NUAK11.94182465
23KSR21.93273735
24CDK191.79189652
25DAPK11.75258278
26CAMKK11.73786944
27NTRK11.68788861
28MAP2K41.66889031
29CDK51.64950522
30UHMK11.61633376
31TYRO31.60318510
32ACVR1B1.59754923
33PLK31.55016302
34ERBB31.54226754
35ZAK1.53379944
36CASK1.52131372
37TNIK1.51761293
38MAP3K121.49326988
39KSR11.49275412
40PRPF4B1.41645595
41OXSR11.34422886
42LMTK21.31718567
43CSNK1G11.28153951
44TLK11.26283012
45ICK1.25988046
46PHKG21.25089346
47PHKG11.25089346
48STK381.23964909
49BRSK21.22298264
50GRK11.21743656
51PINK11.21551849
52PLK41.19203117
53ADRBK21.18476884
54MAP3K131.17625354
55MKNK11.15964021
56SIK21.15221547
57RIPK41.14938485
58MAPK131.14639487
59PRKCG1.13017619
60PLK21.12148983
61ARAF1.09881880
62TSSK61.08917095
63GRK51.08769487
64MAP3K21.07304861
65SGK4941.05317227
66SGK2231.05317227
67CDK181.04999931
68PRKCH1.04876744
69CSNK1A1L1.03497765
70CDK151.03041569
71NEK11.03040249
72CDK140.97398504
73PRKCI0.97142358
74CAMK2A0.96170972
75TAOK10.94684546
76CAMK2B0.93352433
77DYRK20.90293347
78CDK11A0.89962683
79CAMKK20.89293241
80INSRR0.88003565
81BUB10.86874222
82SRPK10.85211186
83STK110.83662329
84VRK10.82921066
85WEE10.80923118
86CAMK10.79550288
87FES0.78891932
88DDR20.78305659
89TTK0.77389174
90CSNK1G20.76608700
91PAK30.74116381
92RET0.73936516
93STK390.73644202
94FGR0.73406824
95MARK20.72363435
96WNK40.71820976
97SGK10.68428500
98SGK20.67483960
99SGK30.67482295
100TGFBR10.67419868
101FGFR20.66510717
102MAP2K60.65854419
103RAF10.65171458
104FGFR10.65079261
105DYRK1A0.62464725
106TNK20.62129410
107NME10.62001352
108PLK10.61324293
109LATS20.61045924
110PDK10.61005659
111STK38L0.60939593
112CDC42BPA0.60783853
113ALK0.60761080
114SIK30.60138841
115PDPK10.60084558
116CAMK2G0.59202732
117PRKCZ0.57884569
118PTK2B0.57761676
119MAP3K60.57035481
120ATR0.53855036
121TAF10.53706710
122MAP3K10.53675027
123RPS6KA30.53056963
124BCR0.53006045
125VRK20.52294452
126MAP3K70.51497257
127STK160.50937706
128WNK10.47788190
129CAMK2D0.47664797
130FYN0.46201642
131NEK60.45851038
132MAPK100.45228375
133PNCK0.44654271
134CSNK1A10.41922645
135BRSK10.41598901
136PRKCE0.40520967
137PKN10.40490932
138CAMK40.40170557
139PRKD20.39757380
140RIPK10.39058169
141AKT30.37458160
142EIF2AK10.36425358
143ATM0.36397323
144DYRK30.35764735
145CSNK1G30.35265855
146MAPKAPK30.34884353
147CCNB10.34714926
148MAP2K10.34642520
149ROCK20.34621167
150CAMK1G0.34283164
151BCKDK0.34134421
152MAP3K50.32683191
153CSNK1E0.32280007
154MAPKAPK50.31596810
155ADRBK10.30538872
156NLK0.29296526
157TAOK20.29195306

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.59994073
2Synaptic vesicle cycle_Homo sapiens_hsa047213.32833526
3GABAergic synapse_Homo sapiens_hsa047272.77149263
4Olfactory transduction_Homo sapiens_hsa047402.72646627
5Protein export_Homo sapiens_hsa030602.64569618
6Glutamatergic synapse_Homo sapiens_hsa047242.56670990
7Circadian entrainment_Homo sapiens_hsa047132.55887436
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50416992
9Nitrogen metabolism_Homo sapiens_hsa009102.50118773
10Morphine addiction_Homo sapiens_hsa050322.43955160
11Long-term potentiation_Homo sapiens_hsa047202.37791347
12Amphetamine addiction_Homo sapiens_hsa050312.30342875
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.19401948
14Salivary secretion_Homo sapiens_hsa049702.11050619
15Insulin secretion_Homo sapiens_hsa049112.03279029
16Dopaminergic synapse_Homo sapiens_hsa047282.02819422
17Fatty acid elongation_Homo sapiens_hsa000621.96891817
18Propanoate metabolism_Homo sapiens_hsa006401.95487614
19Vitamin B6 metabolism_Homo sapiens_hsa007501.90556552
20Proteasome_Homo sapiens_hsa030501.85880837
21Selenocompound metabolism_Homo sapiens_hsa004501.85776877
22Gastric acid secretion_Homo sapiens_hsa049711.83471157
23Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.79303566
24Oxidative phosphorylation_Homo sapiens_hsa001901.75918582
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.71942990
26Cholinergic synapse_Homo sapiens_hsa047251.71857662
27Cocaine addiction_Homo sapiens_hsa050301.69797433
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.69343165
29Non-homologous end-joining_Homo sapiens_hsa034501.68841582
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.68254654
31Steroid biosynthesis_Homo sapiens_hsa001001.57293891
32Long-term depression_Homo sapiens_hsa047301.56611901
33Taste transduction_Homo sapiens_hsa047421.54012359
34Basal transcription factors_Homo sapiens_hsa030221.52623962
35Fanconi anemia pathway_Homo sapiens_hsa034601.52148930
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.51734243
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49171945
38Parkinsons disease_Homo sapiens_hsa050121.48877807
39Renin secretion_Homo sapiens_hsa049241.47185227
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.46757077
41Collecting duct acid secretion_Homo sapiens_hsa049661.43979865
42Homologous recombination_Homo sapiens_hsa034401.43224777
43Serotonergic synapse_Homo sapiens_hsa047261.43046394
44Calcium signaling pathway_Homo sapiens_hsa040201.41033860
45RNA degradation_Homo sapiens_hsa030181.39849101
46Oxytocin signaling pathway_Homo sapiens_hsa049211.39158389
47Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.36399916
48RNA polymerase_Homo sapiens_hsa030201.35396236
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.35124249
50Gap junction_Homo sapiens_hsa045401.31946667
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.30725230
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30216424
53GnRH signaling pathway_Homo sapiens_hsa049121.27636886
54Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.16809700
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16417254
56cAMP signaling pathway_Homo sapiens_hsa040241.15295951
57Axon guidance_Homo sapiens_hsa043601.09974704
58Mismatch repair_Homo sapiens_hsa034301.06473501
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05896557
60Fatty acid biosynthesis_Homo sapiens_hsa000611.04828936
61Pancreatic secretion_Homo sapiens_hsa049721.03924000
62Vibrio cholerae infection_Homo sapiens_hsa051101.02047450
63Peroxisome_Homo sapiens_hsa041461.01807820
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.00483587
65Huntingtons disease_Homo sapiens_hsa050160.99134875
66beta-Alanine metabolism_Homo sapiens_hsa004100.98592424
67ErbB signaling pathway_Homo sapiens_hsa040120.98552095
68Alzheimers disease_Homo sapiens_hsa050100.98403658
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97755700
70Estrogen signaling pathway_Homo sapiens_hsa049150.97076010
71Type II diabetes mellitus_Homo sapiens_hsa049300.96967378
72Arginine biosynthesis_Homo sapiens_hsa002200.95438160
73Tryptophan metabolism_Homo sapiens_hsa003800.95118968
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.95048424
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94482729
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.93879675
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91863088
78Sulfur metabolism_Homo sapiens_hsa009200.91156996
79Ether lipid metabolism_Homo sapiens_hsa005650.89855689
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.89726952
81Bile secretion_Homo sapiens_hsa049760.89271214
82Dorso-ventral axis formation_Homo sapiens_hsa043200.89071698
83Glioma_Homo sapiens_hsa052140.88359615
84Melanogenesis_Homo sapiens_hsa049160.88173251
85Regulation of autophagy_Homo sapiens_hsa041400.85977224
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.85956798
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.85338959
88RNA transport_Homo sapiens_hsa030130.83138088
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79639326
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77321583
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76737148
92Phospholipase D signaling pathway_Homo sapiens_hsa040720.75847303
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.74569635
94Thyroid hormone synthesis_Homo sapiens_hsa049180.74353607
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74081349
96Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74022427
97Oocyte meiosis_Homo sapiens_hsa041140.73727304
98Vascular smooth muscle contraction_Homo sapiens_hsa042700.73534656
99Purine metabolism_Homo sapiens_hsa002300.70416348
100Cardiac muscle contraction_Homo sapiens_hsa042600.70100612
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.68694804
102Linoleic acid metabolism_Homo sapiens_hsa005910.67583336
103Choline metabolism in cancer_Homo sapiens_hsa052310.66149190
104Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65389231
105Caffeine metabolism_Homo sapiens_hsa002320.63915089
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63709367
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63640900
108Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61751253
109Pyruvate metabolism_Homo sapiens_hsa006200.58459075
110Hedgehog signaling pathway_Homo sapiens_hsa043400.58231360
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58131613
112MAPK signaling pathway_Homo sapiens_hsa040100.57778292
113Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56400996
114Metabolic pathways_Homo sapiens_hsa011000.55987614
115Butanoate metabolism_Homo sapiens_hsa006500.55756784
116Glutathione metabolism_Homo sapiens_hsa004800.54532773
117VEGF signaling pathway_Homo sapiens_hsa043700.53460898
118One carbon pool by folate_Homo sapiens_hsa006700.53117926
119Hippo signaling pathway_Homo sapiens_hsa043900.53026512
120Circadian rhythm_Homo sapiens_hsa047100.52946496
121Phototransduction_Homo sapiens_hsa047440.51318931
122Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49844921
123Glucagon signaling pathway_Homo sapiens_hsa049220.49193151
124Endocytosis_Homo sapiens_hsa041440.49087339
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.46624283
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45983333
127Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45167167
128Ras signaling pathway_Homo sapiens_hsa040140.45143187
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.43616450
130Neurotrophin signaling pathway_Homo sapiens_hsa047220.43340244
131Rap1 signaling pathway_Homo sapiens_hsa040150.42430848
132Fatty acid degradation_Homo sapiens_hsa000710.42215760
133Chemical carcinogenesis_Homo sapiens_hsa052040.42118816
134mTOR signaling pathway_Homo sapiens_hsa041500.41894994
1352-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41542297
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41436685
137Base excision repair_Homo sapiens_hsa034100.40578909
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.40317877
139Pyrimidine metabolism_Homo sapiens_hsa002400.39407594
140Retinol metabolism_Homo sapiens_hsa008300.39397869
141Cyanoamino acid metabolism_Homo sapiens_hsa004600.39138656
142Prion diseases_Homo sapiens_hsa050200.38381649
143Nucleotide excision repair_Homo sapiens_hsa034200.37120470
144Wnt signaling pathway_Homo sapiens_hsa043100.37032428
145Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36366755
146Alcoholism_Homo sapiens_hsa050340.36095826
147Dilated cardiomyopathy_Homo sapiens_hsa054140.35341655
148Primary bile acid biosynthesis_Homo sapiens_hsa001200.34942961
149Endometrial cancer_Homo sapiens_hsa052130.34251257
150SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32957496
151Inositol phosphate metabolism_Homo sapiens_hsa005620.32678879
152Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32194503
153Insulin signaling pathway_Homo sapiens_hsa049100.31471783
154Ovarian steroidogenesis_Homo sapiens_hsa049130.30492363
155Non-small cell lung cancer_Homo sapiens_hsa052230.30449013
156Renal cell carcinoma_Homo sapiens_hsa052110.29041630
157Type I diabetes mellitus_Homo sapiens_hsa049400.28146492
158Fatty acid metabolism_Homo sapiens_hsa012120.24361484
159Glycerolipid metabolism_Homo sapiens_hsa005610.23793510

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