FAM26E

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1extracellular fibril organization (GO:0043206)5.28686443
2sequestering of extracellular ligand from receptor (GO:0035581)4.91158779
3blood vessel maturation (GO:0001955)4.40460603
4fibril organization (GO:0097435)4.35855150
5collagen fibril organization (GO:0030199)4.34434431
6regulation of integrin-mediated signaling pathway (GO:2001044)4.33839777
7desmosome organization (GO:0002934)4.25041697
8protein heterotrimerization (GO:0070208)4.12130791
9endodermal cell differentiation (GO:0035987)3.96875511
10retina vasculature morphogenesis in camera-type eye (GO:0061299)3.96079438
11vocalization behavior (GO:0071625)3.82008870
12negative regulation of protein localization to cell surface (GO:2000009)3.71393724
13cell migration involved in heart development (GO:0060973)3.59043247
14negative regulation of synaptic transmission, GABAergic (GO:0032229)3.57641583
15extracellular matrix assembly (GO:0085029)3.55487804
16dermatan sulfate biosynthetic process (GO:0030208)3.55096150
17cell adhesion mediated by integrin (GO:0033627)3.51491033
18kidney mesenchyme development (GO:0072074)3.49514637
19vascular endothelial growth factor signaling pathway (GO:0038084)3.40477070
20metanephric mesenchyme development (GO:0072075)3.39966354
21dermatan sulfate metabolic process (GO:0030205)3.38354726
22substrate-dependent cell migration (GO:0006929)3.33206699
23sprouting angiogenesis (GO:0002040)3.32496058
24cellular response to vitamin (GO:0071295)3.31247114
25endothelium development (GO:0003158)3.29554673
26protein localization to cell surface (GO:0034394)3.26603747
27substrate adhesion-dependent cell spreading (GO:0034446)3.22760649
28extracellular regulation of signal transduction (GO:1900115)3.21727323
29extracellular negative regulation of signal transduction (GO:1900116)3.21727323
30negative regulation of complement activation (GO:0045916)3.19627946
31glomerular basement membrane development (GO:0032836)3.19620217
32peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.19340583
33negative regulation of nitric-oxide synthase activity (GO:0051001)3.09754822
34chondrocyte proliferation (GO:0035988)3.07063881
35endocardial cushion development (GO:0003197)3.06997232
36sphingoid metabolic process (GO:0046519)3.05978431
37glutamate secretion (GO:0014047)3.05870233
38bone trabecula formation (GO:0060346)3.04972891
39negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.03414788
40positive regulation of cardiac muscle cell differentiation (GO:2000727)2.99311989
41positive regulation of fibroblast migration (GO:0010763)2.98317261
42pericardium development (GO:0060039)2.97773581
43regulation of long-term neuronal synaptic plasticity (GO:0048169)2.97577123
44neuron projection extension involved in neuron projection guidance (GO:1902284)2.96761250
45axon extension involved in axon guidance (GO:0048846)2.96761250
46positive regulation of vesicle fusion (GO:0031340)2.96480702
47regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.94432571
48synaptic vesicle docking involved in exocytosis (GO:0016081)2.94060039
49positive regulation of synapse assembly (GO:0051965)2.90829183
50ionotropic glutamate receptor signaling pathway (GO:0035235)2.90752282
51protein localization to synapse (GO:0035418)2.89966219
52artery development (GO:0060840)2.87130420
53negative regulation of smooth muscle cell migration (GO:0014912)2.86243168
54glutamate receptor signaling pathway (GO:0007215)2.86167256
55negative chemotaxis (GO:0050919)2.86151702
56cellular response to vitamin D (GO:0071305)2.84138156
57presynaptic membrane assembly (GO:0097105)2.83974893
58cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.79789333
59transferrin transport (GO:0033572)2.79314514
60induction of positive chemotaxis (GO:0050930)2.77946357
61negative regulation of dendrite morphogenesis (GO:0050774)2.77704012
62skin morphogenesis (GO:0043589)2.76606405
63negative regulation of activin receptor signaling pathway (GO:0032926)2.74342949
64multicellular organismal catabolic process (GO:0044243)2.73822330
65ATP hydrolysis coupled proton transport (GO:0015991)2.71944297
66energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.71944297
67neuron cell-cell adhesion (GO:0007158)2.70415144
68trivalent inorganic cation transport (GO:0072512)2.69880917
69ferric iron transport (GO:0015682)2.69880917
70virion attachment to host cell (GO:0019062)2.68192543
71adhesion of symbiont to host cell (GO:0044650)2.68192543
72neural crest cell development (GO:0014032)2.68143328
73multicellular organismal metabolic process (GO:0044236)2.67792971
74cranial suture morphogenesis (GO:0060363)2.67011072
75cell migration involved in sprouting angiogenesis (GO:0002042)2.65529904
76regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.63748363
77synaptic vesicle exocytosis (GO:0016079)2.63335560
78presynaptic membrane organization (GO:0097090)2.63036711
79positive regulation of endothelial cell apoptotic process (GO:2000353)2.62528767
80molting cycle (GO:0042303)2.62393663
81hair cycle (GO:0042633)2.62393663
82negative regulation of platelet activation (GO:0010544)2.61747299
83angiogenesis involved in wound healing (GO:0060055)2.61516667
84extracellular matrix disassembly (GO:0022617)2.61200199
85positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.59264941
86regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.58895751
87negative regulation of stem cell proliferation (GO:2000647)2.58710513
88long-term synaptic potentiation (GO:0060291)2.58630017
89fibroblast migration (GO:0010761)2.57404560
90negative regulation of axon extension involved in axon guidance (GO:0048843)2.56957497
91negative regulation of cartilage development (GO:0061037)2.56519185
92positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.55308956
93endothelial cell proliferation (GO:0001935)2.54653414
94positive regulation of vasculogenesis (GO:2001214)2.54480746
95craniofacial suture morphogenesis (GO:0097094)2.53772453
96gonadal mesoderm development (GO:0007506)2.53753266
97regulation of axon extension involved in axon guidance (GO:0048841)2.52824156
98membrane assembly (GO:0071709)2.52654869
99regulation of gonadotropin secretion (GO:0032276)2.52314349
100cell-matrix adhesion (GO:0007160)2.51734472
101smooth muscle tissue development (GO:0048745)2.51525309
102regulation of sarcomere organization (GO:0060297)2.50987017
103type B pancreatic cell proliferation (GO:0044342)2.50983211
104gamma-aminobutyric acid signaling pathway (GO:0007214)2.50944018
105regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.50420031
106neurotransmitter-gated ion channel clustering (GO:0072578)2.49391651
107neuron-neuron synaptic transmission (GO:0007270)2.48877484
108response to gravity (GO:0009629)2.48783701
109negative regulation of endothelial cell proliferation (GO:0001937)2.48494762
110negative regulation of keratinocyte proliferation (GO:0010839)2.48485165
111behavioral response to cocaine (GO:0048148)2.46638401
112collagen metabolic process (GO:0032963)2.46593457
113cell-substrate adhesion (GO:0031589)2.46511853
114negative regulation of protein activation cascade (GO:2000258)2.46164764
115synaptic transmission, glutamatergic (GO:0035249)2.46072876
116negative regulation of BMP signaling pathway (GO:0030514)2.45552501
117chondrocyte development (GO:0002063)2.45344130
118negative regulation of adherens junction organization (GO:1903392)2.44906239
119negative regulation of focal adhesion assembly (GO:0051895)2.44906239
120negative regulation of cell junction assembly (GO:1901889)2.44906239
121regulation of lipoprotein metabolic process (GO:0050746)2.44575330
122regulation of cardiac muscle cell differentiation (GO:2000725)2.43878591
123positive regulation of blood vessel endothelial cell migration (GO:0043536)2.43499067
124heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.43424690
125regulation of chondrocyte differentiation (GO:0032330)2.43411636
126collagen catabolic process (GO:0030574)2.43133586
127positive regulation of cartilage development (GO:0061036)2.43003647
128tonic smooth muscle contraction (GO:0014820)2.42877604
129regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.42341436
130positive regulation of endothelial cell migration (GO:0010595)2.42325607
131regulation of glutamate secretion (GO:0014048)2.42030069
132mesodermal cell differentiation (GO:0048333)2.41712219
133cell proliferation involved in kidney development (GO:0072111)2.41585754
134cardiac myofibril assembly (GO:0055003)2.41394502
135regulation of fibroblast migration (GO:0010762)2.41189574
136regulation of glutamate receptor signaling pathway (GO:1900449)2.41077644
137positive regulation of Rho protein signal transduction (GO:0035025)2.40880324
138regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.40605382
139regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.40605382
140basement membrane organization (GO:0071711)2.40405406
141regulation of hippo signaling (GO:0035330)2.39385882
142regulation of cartilage development (GO:0061035)2.39349712
143wound healing, spreading of epidermal cells (GO:0035313)2.39054807
144regulation of excitatory postsynaptic membrane potential (GO:0060079)2.38258275
145positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.37615109
146postsynaptic membrane organization (GO:0001941)2.36112904
147regulation of short-term neuronal synaptic plasticity (GO:0048172)2.35718741
148mesenchymal-epithelial cell signaling (GO:0060638)2.35120669
149peptide cross-linking (GO:0018149)2.34130241
150positive regulation of transforming growth factor beta production (GO:0071636)2.33294857
151lymphangiogenesis (GO:0001946)2.32934443
152multicellular organismal macromolecule metabolic process (GO:0044259)2.31614883
153neuron recognition (GO:0008038)2.31284379
154extracellular matrix organization (GO:0030198)2.29067705
155negative regulation of chondrocyte differentiation (GO:0032331)2.28515183
156extracellular structure organization (GO:0043062)2.28066576
157regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.27146165
158regulation of synapse assembly (GO:0051963)2.25958258
159regulation of synaptic vesicle exocytosis (GO:2000300)2.25807702
160protein localization to cilium (GO:0061512)2.25768186
161peptidyl-proline hydroxylation (GO:0019511)2.25266920
162regulation of vesicle fusion (GO:0031338)2.24861420
163positive regulation of muscle hypertrophy (GO:0014742)2.24775624
164positive regulation of cardiac muscle hypertrophy (GO:0010613)2.24775624
165ephrin receptor signaling pathway (GO:0048013)2.23575217

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.74487707
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.64448927
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.90799147
4EZH2_22144423_ChIP-Seq_EOC_Human2.79261825
5SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.68253386
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.64980789
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.64097343
8EED_16625203_ChIP-ChIP_MESCs_Mouse2.57924348
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.56152316
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.46193180
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.46193180
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.37663265
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.36425681
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.35636640
15TP53_18474530_ChIP-ChIP_U2OS_Human2.33449786
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.21673328
17JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19021204
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.16188535
19BRD4_25478319_ChIP-Seq_HGPS_Human2.11033313
20WT1_19549856_ChIP-ChIP_CCG9911_Human2.07524029
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.03792940
22GATA2_21666600_ChIP-Seq_HMVEC_Human2.02210524
23* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.00149595
24* NRF2_20460467_ChIP-Seq_MEFs_Mouse2.00149595
25MTF2_20144788_ChIP-Seq_MESCs_Mouse1.95384893
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.91572812
27CJUN_26792858_Chip-Seq_BT549_Human1.91045164
28PIAS1_25552417_ChIP-Seq_VCAP_Human1.88055097
29RARG_19884340_ChIP-ChIP_MEFs_Mouse1.85669670
30CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85072141
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.81103053
32SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.80061146
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.79356904
34TAF15_26573619_Chip-Seq_HEK293_Human1.73750754
35ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.73340966
36P300_19829295_ChIP-Seq_ESCs_Human1.72134223
37SMAD4_21799915_ChIP-Seq_A2780_Human1.71198738
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.68266049
39CDX2_19796622_ChIP-Seq_MESCs_Mouse1.65547991
40AR_21572438_ChIP-Seq_LNCaP_Human1.64194906
41TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.63965167
42RNF2_27304074_Chip-Seq_ESCs_Mouse1.63743029
43PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.62979028
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61935008
45EP300_21415370_ChIP-Seq_HL-1_Mouse1.61430222
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.61049813
47ZNF217_24962896_ChIP-Seq_MCF-7_Human1.58843278
48FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.58213509
49TP53_16413492_ChIP-PET_HCT116_Human1.56011724
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52989744
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.51983207
52ESR1_21235772_ChIP-Seq_MCF-7_Human1.51818534
53TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.49882297
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.48269879
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.47883324
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47090538
57FUS_26573619_Chip-Seq_HEK293_Human1.46180092
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45899371
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45472037
60BCAT_22108803_ChIP-Seq_LS180_Human1.44407625
61EZH2_27294783_Chip-Seq_NPCs_Mouse1.43623284
62CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.42421720
63EZH2_27294783_Chip-Seq_ESCs_Mouse1.39601939
64STAT3_23295773_ChIP-Seq_U87_Human1.38926829
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36471747
66AHR_22903824_ChIP-Seq_MCF-7_Human1.35104343
67ZNF274_21170338_ChIP-Seq_K562_Hela1.35039701
68PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34498600
69TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.34454312
70JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.34368694
71RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33273600
72VDR_22108803_ChIP-Seq_LS180_Human1.33000353
73IGF1R_20145208_ChIP-Seq_DFB_Human1.32659595
74ARNT_22903824_ChIP-Seq_MCF-7_Human1.31539454
75SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28783590
76TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28006030
77GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27243473
78AR_25329375_ChIP-Seq_VCAP_Human1.25654892
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25319283
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.24328096
81OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23739178
82UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.23588654
83TP53_20018659_ChIP-ChIP_R1E_Mouse1.21972123
84BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21932869
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.21404112
86KDM2B_26808549_Chip-Seq_REH_Human1.18130133
87JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.17965287
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.17081193
89TCF4_23295773_ChIP-Seq_U87_Human1.15686368
90SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.14908838
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12702040
92CDX2_22108803_ChIP-Seq_LS180_Human1.11808350
93AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11532048
94* CRX_20693478_ChIP-Seq_RETINA_Mouse1.10827599
95PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.10390810
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.10189637
97CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10002736
98NFE2_27457419_Chip-Seq_LIVER_Mouse1.09834275
99RXR_22108803_ChIP-Seq_LS180_Human1.08434686
100CBX2_27304074_Chip-Seq_ESCs_Mouse1.08309099
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06809172
102TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.06599007
103PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06096520
104SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.05881964
105* FLI1_21867929_ChIP-Seq_TH2_Mouse1.04283938
106OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04000428
107SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03735703
108ER_23166858_ChIP-Seq_MCF-7_Human1.03541633
109TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03178922
110FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02901199
111CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.02458716
112JUN_21703547_ChIP-Seq_K562_Human1.02287315
113DROSHA_22980978_ChIP-Seq_HELA_Human1.01661620
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00991947
115CBP_20019798_ChIP-Seq_JUKART_Human1.00991947
116SOX2_20726797_ChIP-Seq_SW620_Human1.00982924
117PRDM14_20953172_ChIP-Seq_ESCs_Human1.00793093
118RNF2_27304074_Chip-Seq_NSC_Mouse0.98125741
119* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.97677206
120NANOG_18555785_Chip-Seq_ESCs_Mouse0.95658456
121BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95121860
122RUNX2_22187159_ChIP-Seq_PCA_Human0.94599439
123SOX2_21211035_ChIP-Seq_LN229_Gbm0.94442531
124TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.94188097
125ESR1_20079471_ChIP-ChIP_T-47D_Human0.93851896
126EWS_26573619_Chip-Seq_HEK293_Human0.92474875
127RING1B_27294783_Chip-Seq_ESCs_Mouse0.91150123
128MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.90435550
129TCF4_22108803_ChIP-Seq_LS180_Human0.89516321
130WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.87703612
131EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.87498271
132TP63_23658742_ChIP-Seq_EP156T_Human0.87320172
133NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87099871
134CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.86821235
135E2F1_18555785_Chip-Seq_ESCs_Mouse0.84641933

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen7.05879287
2MP0005275_abnormal_skin_tensile5.48563449
3MP0005503_abnormal_tendon_morphology5.28037071
4MP0001958_emphysema3.30347052
5MP0003279_aneurysm3.05278733
6MP0003880_abnormal_central_pattern2.86568817
7MP0003705_abnormal_hypodermis_morpholog2.83863098
8MP0010386_abnormal_urinary_bladder2.75866395
9MP0002009_preneoplasia2.74387503
10MP0009384_cardiac_valve_regurgitation2.55612231
11MP0003941_abnormal_skin_development2.51469967
12MP0004859_abnormal_synaptic_plasticity2.43830415
13MP0002060_abnormal_skin_morphology2.17273780
14MP0002295_abnormal_pulmonary_circulatio2.08721300
15MP0006054_spinal_hemorrhage2.04819435
16MP0009780_abnormal_chondrocyte_physiolo2.04035717
17MP0002837_dystrophic_cardiac_calcinosis1.96995201
18MP0004084_abnormal_cardiac_muscle1.90713046
19MP0005623_abnormal_meninges_morphology1.87963253
20MP0001542_abnormal_bone_strength1.80352209
21MP0001968_abnormal_touch/_nociception1.80121961
22MP0002736_abnormal_nociception_after1.79042919
23MP0004272_abnormal_basement_membrane1.75222342
24MP0002108_abnormal_muscle_morphology1.72700407
25MP0005508_abnormal_skeleton_morphology1.69550005
26MP0005171_absent_coat_pigmentation1.69253763
27MP0000516_abnormal_urinary_system1.61757204
28MP0005367_renal/urinary_system_phenotyp1.61757204
29MP0003635_abnormal_synaptic_transmissio1.52030838
30MP0000569_abnormal_digit_pigmentation1.46442955
31MP0005595_abnormal_vascular_smooth1.45643473
32MP0003385_abnormal_body_wall1.44458728
33MP0002282_abnormal_trachea_morphology1.39244273
34MP0001243_abnormal_dermal_layer1.37611443
35MP0009046_muscle_twitch1.35870736
36MP0002249_abnormal_larynx_morphology1.35582519
37MP0004883_abnormal_blood_vessel1.32770033
38MP0002063_abnormal_learning/memory/cond1.32548348
39MP0004036_abnormal_muscle_relaxation1.32448083
40MP0009745_abnormal_behavioral_response1.31977316
41MP0003566_abnormal_cell_adhesion1.30391390
42MP0000013_abnormal_adipose_tissue1.29884961
43MP0001879_abnormal_lymphatic_vessel1.27018496
44MP0010368_abnormal_lymphatic_system1.25744451
45MP0003045_fibrosis1.25655456
46MP0002796_impaired_skin_barrier1.25088645
47MP0003828_pulmonary_edema1.24640829
48MP0009053_abnormal_anal_canal1.23523439
49MP0002735_abnormal_chemical_nociception1.21362068
50MP0010771_integument_phenotype1.20199923
51MP0002168_other_aberrant_phenotype1.18302320
52MP0005257_abnormal_intraocular_pressure1.17842770
53MP0008004_abnormal_stomach_pH1.15968555
54MP0001299_abnormal_eye_distance/1.14825931
55MP0008775_abnormal_heart_ventricle1.13580988
56MP0002064_seizures1.10145785
57MP0000534_abnormal_ureter_morphology1.08468525
58MP0002128_abnormal_blood_circulation1.08285934
59MP0004145_abnormal_muscle_electrophysio1.06305634
60MP0002572_abnormal_emotion/affect_behav1.04635446
61MP0002896_abnormal_bone_mineralization1.03760189
62MP0001501_abnormal_sleep_pattern1.00969048
63MP0000749_muscle_degeneration1.00848787
64MP0000751_myopathy0.99486057
65MP0009250_abnormal_appendicular_skeleto0.98896125
66MP0005164_abnormal_response_to0.98301065
67MP0004484_altered_response_of0.98082966
68MP0001177_atelectasis0.96495287
69MP0005023_abnormal_wound_healing0.96045226
70MP0004270_analgesia0.95632378
71MP0005670_abnormal_white_adipose0.94089100
72MP0004215_abnormal_myocardial_fiber0.93981770
73MP0004858_abnormal_nervous_system0.91674787
74MP0000537_abnormal_urethra_morphology0.90656444
75MP0001188_hyperpigmentation0.90572526
76MP0002822_catalepsy0.89095852
77MP0003122_maternal_imprinting0.89069143
78MP0001440_abnormal_grooming_behavior0.88762210
79MP0000759_abnormal_skeletal_muscle0.87342277
80MP0001614_abnormal_blood_vessel0.85555665
81MP0005388_respiratory_system_phenotype0.84879523
82MP0002133_abnormal_respiratory_system0.84879523
83MP0000767_abnormal_smooth_muscle0.84739890
84MP0002272_abnormal_nervous_system0.84529476
85MP0005390_skeleton_phenotype0.83932195
86MP0005165_increased_susceptibility_to0.83714294
87MP0001346_abnormal_lacrimal_gland0.82618377
88MP0006276_abnormal_autonomic_nervous0.82340800
89MP0003091_abnormal_cell_migration0.80622209
90MP0000762_abnormal_tongue_morphology0.78409264
91MP0001661_extended_life_span0.78297799
92MP0000163_abnormal_cartilage_morphology0.77774493
93MP0002127_abnormal_cardiovascular_syste0.77191870
94MP0001984_abnormal_olfaction0.77093390
95MP0009379_abnormal_foot_pigmentation0.76489337
96MP0002734_abnormal_mechanical_nocicepti0.76183906
97MP0000343_altered_response_to0.75914413
98MP0005464_abnormal_platelet_physiology0.75838350
99MP0000538_abnormal_urinary_bladder0.75158712
100MP0002972_abnormal_cardiac_muscle0.75068764
101MP0000733_abnormal_muscle_development0.74139109
102MP0003942_abnormal_urinary_system0.74126225
103MP0004130_abnormal_muscle_cell0.73718596
104MP0005369_muscle_phenotype0.73690519
105MP0000427_abnormal_hair_cycle0.73262073
106MP0000778_abnormal_nervous_system0.71761400
107MP0000249_abnormal_blood_vessel0.71123166
108MP0000750_abnormal_muscle_regeneration0.69609705
109MP0005620_abnormal_muscle_contractility0.69244350
110MP0010352_gastrointestinal_tract_polyps0.68847189
111MP0000647_abnormal_sebaceous_gland0.68114239
112MP0010030_abnormal_orbit_morphology0.67998784
113MP0000428_abnormal_craniofacial_morphol0.67968427
114MP0002184_abnormal_innervation0.67459336
115MP0006138_congestive_heart_failure0.67342906
116MP0003315_abnormal_perineum_morphology0.66505321
117MP0002332_abnormal_exercise_endurance0.65811088
118MP0002733_abnormal_thermal_nociception0.65680988
119MP0003755_abnormal_palate_morphology0.65499813
120MP0000049_abnormal_middle_ear0.65209292
121MP0001544_abnormal_cardiovascular_syste0.64417226
122MP0005385_cardiovascular_system_phenoty0.64417226
123MP0002876_abnormal_thyroid_physiology0.64225805
124MP0002933_joint_inflammation0.63855295
125MP0001970_abnormal_pain_threshold0.62505624
126MP0002925_abnormal_cardiovascular_devel0.62201766
127MP0000579_abnormal_nail_morphology0.62068653
128MP0000230_abnormal_systemic_arterial0.61841851
129MP0004085_abnormal_heartbeat0.61824983
130MP0005451_abnormal_body_composition0.61564316
131MP0003252_abnormal_bile_duct0.61514595
132MP0005501_abnormal_skin_physiology0.60742203
133MP0002163_abnormal_gland_morphology0.60357158
134MP0002115_abnormal_skeleton_extremities0.60185475
135MP0005395_other_phenotype0.59925483
136MP0009697_abnormal_copulation0.59204755
137MP0002067_abnormal_sensory_capabilities0.58609373
138MP0004134_abnormal_chest_morphology0.58494518
139MP0003448_altered_tumor_morphology0.58002303
140MP0003283_abnormal_digestive_organ0.57436714
141MP0003950_abnormal_plasma_membrane0.57431819
142MP0004087_abnormal_muscle_fiber0.56875263
143MP0002102_abnormal_ear_morphology0.56321792
144MP0005084_abnormal_gallbladder_morpholo0.55948130
145MP0005187_abnormal_penis_morphology0.55227294
146MP0002106_abnormal_muscle_physiology0.51997608

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.70667799
2Aortic aneurysm (HP:0004942)5.93423779
3Premature rupture of membranes (HP:0001788)5.85244316
4Vascular tortuosity (HP:0004948)5.50498913
5Bladder diverticulum (HP:0000015)3.89450243
6Aortic dissection (HP:0002647)3.89430629
7Soft skin (HP:0000977)3.84513856
8Focal motor seizures (HP:0011153)3.76056293
9Dilatation of the ascending aorta (HP:0005111)3.70799429
10Abnormality of dentin (HP:0010299)3.67687877
11Wormian bones (HP:0002645)3.59816274
12Atrophic scars (HP:0001075)3.58846410
13Spondylolisthesis (HP:0003302)3.49372539
14Vertebral compression fractures (HP:0002953)3.47693791
15Follicular hyperkeratosis (HP:0007502)3.44425910
16Overgrowth (HP:0001548)3.21887030
17Fragile skin (HP:0001030)3.17537219
18Increased corneal curvature (HP:0100692)3.16964589
19Keratoconus (HP:0000563)3.16964589
20Wrist flexion contracture (HP:0001239)3.09295376
21Aortic regurgitation (HP:0001659)2.94887709
22Broad metatarsal (HP:0001783)2.92221184
23Mitral valve prolapse (HP:0001634)2.91888068
24Arterial tortuosity (HP:0005116)2.91841490
25Ulnar claw (HP:0001178)2.91550764
26Pulmonary artery stenosis (HP:0004415)2.87437290
27Peritonitis (HP:0002586)2.84598232
28Neonatal short-limb short stature (HP:0008921)2.81060097
29Epileptic encephalopathy (HP:0200134)2.74858057
30Redundant skin (HP:0001582)2.70588955
31Focal seizures (HP:0007359)2.69942415
32Increased mean platelet volume (HP:0011877)2.69431031
33Blue sclerae (HP:0000592)2.69052997
34Biconcave vertebral bodies (HP:0004586)2.68212365
35Alopecia of scalp (HP:0002293)2.67370799
36Mitral stenosis (HP:0001718)2.66793642
37Bowel diverticulosis (HP:0005222)2.64818316
38Shallow orbits (HP:0000586)2.64460892
39Spinal rigidity (HP:0003306)2.61575060
40Abnormal delivery (HP:0001787)2.60407051
41Atelectasis (HP:0100750)2.59793058
42Mesomelia (HP:0003027)2.55858424
43Testicular atrophy (HP:0000029)2.55819316
44Ankle contracture (HP:0006466)2.52214289
45Menorrhagia (HP:0000132)2.51040232
46Broad ribs (HP:0000885)2.49321957
47Distal lower limb amyotrophy (HP:0008944)2.48976136
48Hyperextensible skin (HP:0000974)2.48554095
49Absence seizures (HP:0002121)2.47686588
50Atonic seizures (HP:0010819)2.47458272
51Hyperventilation (HP:0002883)2.41601652
52Narrow nasal bridge (HP:0000446)2.41508915
53Cerebral aneurysm (HP:0004944)2.39117370
54Type 1 muscle fiber predominance (HP:0003803)2.36601481
55Ectopia lentis (HP:0001083)2.36173006
56Mitral regurgitation (HP:0001653)2.36163656
57Corneal dystrophy (HP:0001131)2.34792252
58Right ventricular cardiomyopathy (HP:0011663)2.33691706
59Bradycardia (HP:0001662)2.27874134
60Aortic valve stenosis (HP:0001650)2.23767717
61Abnormal platelet volume (HP:0011876)2.23347926
62Genu recurvatum (HP:0002816)2.20132132
63Slender build (HP:0001533)2.18526373
64Spontaneous hematomas (HP:0007420)2.17867557
65Striae distensae (HP:0001065)2.16033245
66Limited hip movement (HP:0008800)2.14010888
67Palpebral edema (HP:0100540)2.13612592
68Premature skin wrinkling (HP:0100678)2.11997913
69Distal lower limb muscle weakness (HP:0009053)2.10321482
70Dialeptic seizures (HP:0011146)2.10098510
71Hip contracture (HP:0003273)2.09627986
72Abnormality of the calf musculature (HP:0001430)2.09008443
73Nemaline bodies (HP:0003798)2.07211088
74Venous insufficiency (HP:0005293)2.07092996
75Nonimmune hydrops fetalis (HP:0001790)2.07011433
76Abnormality of the acetabulum (HP:0003170)2.05550720
77Cardiovascular calcification (HP:0011915)2.05110294
78Calf muscle hypertrophy (HP:0008981)2.03604443
79Increased connective tissue (HP:0009025)2.02558734
80Lower limb amyotrophy (HP:0007210)2.00521573
81Parakeratosis (HP:0001036)2.00248896
82Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.99728685
83Morphological abnormality of the middle ear (HP:0008609)1.97790833
84Increased variability in muscle fiber diameter (HP:0003557)1.96227210
85Aneurysm (HP:0002617)1.92215810
86Generalized tonic-clonic seizures (HP:0002069)1.92171752
87Hypotrichosis (HP:0001006)1.90712300
88Joint laxity (HP:0001388)1.89858578
89Cervical subluxation (HP:0003308)1.89782865
90Muscle hypertrophy of the lower extremities (HP:0008968)1.89030818
91Osteolytic defects of the phalanges of the hand (HP:0009771)1.88783085
92Osteolytic defects of the hand bones (HP:0009699)1.88783085
93Amblyopia (HP:0000646)1.86220628
94Elbow flexion contracture (HP:0002987)1.85920840
95Ovoid vertebral bodies (HP:0003300)1.85808921
96Muscle fiber inclusion bodies (HP:0100299)1.84301862
97Abnormality of skeletal muscle fiber size (HP:0012084)1.81532805
98Coronal craniosynostosis (HP:0004440)1.80571866
99Venous abnormality (HP:0002624)1.80231146
100Conjunctival telangiectasia (HP:0000524)1.79784125
101Spontaneous abortion (HP:0005268)1.79117086
102Steppage gait (HP:0003376)1.78822138
103Natal tooth (HP:0000695)1.78285969
104Bruising susceptibility (HP:0000978)1.76808071
105Abnormality of the anterior chamber (HP:0000593)1.76704616
106Knee flexion contracture (HP:0006380)1.76491478
107Osteopenia (HP:0000938)1.76250160
108Short hallux (HP:0010109)1.76113624
109Joint stiffness (HP:0001387)1.75237766
110Hypoplasia of the iris (HP:0007676)1.74770110
111Camptodactyly of toe (HP:0001836)1.73146907
112Bulbous nose (HP:0000414)1.72043715
113Round ear (HP:0100830)1.71628043
114Abnormality of proline metabolism (HP:0010907)1.71251004
115Hydroxyprolinuria (HP:0003080)1.71251004
116Mild short stature (HP:0003502)1.70727231
117Absent frontal sinuses (HP:0002688)1.70593734
118Upper limb muscle weakness (HP:0003484)1.70326370
119Osteoarthritis (HP:0002758)1.70204956
120Lipoatrophy (HP:0100578)1.69788623
121Metaphyseal dysplasia (HP:0100255)1.68319918
122Portal hypertension (HP:0001409)1.66914138
123Aplasia/Hypoplasia of the lens (HP:0008063)1.66593070
124Buphthalmos (HP:0000557)1.66076845
125Hematochezia (HP:0002573)1.65879314
126Pulmonic stenosis (HP:0001642)1.65767703
127Hypoventilation (HP:0002791)1.65074594
128Facial diplegia (HP:0001349)1.64457520
129Heterochromia iridis (HP:0001100)1.64360060
130Protruding ear (HP:0000411)1.63991566
131Delayed closure of the anterior fontanelle (HP:0001476)1.63929170
132Wide anterior fontanel (HP:0000260)1.63886765
133Delayed gross motor development (HP:0002194)1.62897746
134Coxa vara (HP:0002812)1.62810469
135Erythema (HP:0010783)1.62160876
136Insidious onset (HP:0003587)1.61445863
137Termporal pattern (HP:0011008)1.61445863
138Mildly elevated creatine phosphokinase (HP:0008180)1.61325101
139Infantile muscular hypotonia (HP:0008947)1.61277884
140Progressive cerebellar ataxia (HP:0002073)1.61030965
141Hypoplastic ischia (HP:0003175)1.60876606
142Cerebral inclusion bodies (HP:0100314)1.60199476
143Full cheeks (HP:0000293)1.59897372
144Recurrent corneal erosions (HP:0000495)1.59887835
145Inguinal hernia (HP:0000023)1.57188827

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.11216857
2TIE14.17090047
3MAP3K123.40789749
4RIPK43.37730638
5EPHA43.13853256
6LATS22.98029303
7TGFBR22.93056451
8PLK22.92830392
9FER2.71709036
10NTRK32.67229585
11MYLK2.61289303
12EPHA32.55892681
13BMPR22.44267069
14NEK92.42832819
15BCR2.12328465
16PIM22.03575556
17FRK1.98512904
18ARAF1.95605508
19MUSK1.95372755
20ZAK1.76982151
21ERBB31.68461041
22STK31.68336245
23MAP2K71.59057350
24PTK2B1.58998367
25PDGFRA1.56121806
26STK38L1.54476389
27TGFBR11.53501585
28AKT31.52087270
29MINK11.51313283
30KIT1.50471741
31NUAK11.50124875
32PRPF4B1.48108371
33DAPK11.45107081
34TAOK21.43804095
35MAP3K41.40904526
36PDK21.40755037
37SIK31.40713018
38TNK21.40589632
39PTK21.40212701
40DDR21.37707302
41NTRK11.33856260
42LATS11.32764315
43EPHB21.26661148
44PDK41.26151260
45PDK31.26151260
46TRPM71.25560809
47PIK3CA1.25171562
48DAPK21.18910339
49MAP2K41.14399330
50GRK11.12463288
51FLT31.12302203
52ILK1.09810547
53TEC1.04407261
54PRKG21.02532064
55PAK31.01258395
56PRKCE0.98631357
57GRK50.97400468
58TESK10.97059817
59OBSCN0.93789678
60CDK190.92027770
61PRKCG0.90401713
62KDR0.87969605
63CAMK2A0.86568265
64MAPK70.86546023
65ACVR1B0.85585906
66DAPK30.84902556
67PRKD20.83770185
68MARK10.82193780
69BRAF0.80551083
70MAP2K10.80322451
71LIMK10.80188050
72DMPK0.77094379
73INSRR0.76564846
74ERBB40.76004207
75TTN0.73915783
76KSR10.72223165
77PIK3CG0.71336933
78NEK60.68284603
79RAF10.66479081
80MAP3K130.66143558
81CDK50.64270280
82MELK0.61193433
83SIK20.60505770
84ADRBK10.60376556
85MAP3K90.60202340
86MAP3K70.59937944
87FGFR20.57429754
88ROCK10.57308616
89PRKD10.55438288
90SGK20.54816879
91CDK140.54523507
92MAPK130.53847847
93PAK60.52900810
94PRKAA20.51958161
95NLK0.50467997
96BRSK20.48527765
97CDK180.47936976
98ABL10.47724472
99STK390.47399889
100MAP3K50.46474512
101CAMK2B0.45804344
102BMX0.44639721
103CDC42BPA0.44567226
104YES10.42977634
105PLK30.42696431
106OXSR10.42094921
107FGR0.41465338
108GSK3A0.41411097
109PKN10.41356842
110ROCK20.40528053
111JAK10.39873452
112CDK150.38555762
113DYRK1A0.38128235
114PAK40.38073300
115MAP3K30.37909529
116ADRBK20.37743245
117MAP3K20.37694765
118NME10.37070137
119CDK80.36019571
120INSR0.35767861
121MAP3K60.35289115
122STK380.34971578
123PAK10.34737737
124PAK20.33863865
125ABL20.33360547
126PINK10.32380909
127MAPKAPK30.32206998
128PNCK0.31946107
129PDGFRB0.31437260
130MET0.30982832
131CAMK2G0.30774883
132GRK70.30767657
133EIF2AK30.30733361
134MOS0.30400758
135PRKG10.29011309
136IGF1R0.28896303
137PRKCH0.28063661
138SGK4940.27447159
139SGK2230.27447159
140WNK10.27363108
141STK160.27129932
142CAMK10.26662477
143CDK11A0.25973519
144MAPK120.25733902
145PRKACA0.25133545
146PRKCZ0.25044279
147BMPR1B0.24970180
148MAPKAPK50.22442720
149PRKD30.21240646
150MAP4K20.20797277
151SRC0.19617588

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.91047883
2Collecting duct acid secretion_Homo sapiens_hsa049662.84216445
3Synaptic vesicle cycle_Homo sapiens_hsa047212.35842235
4Vibrio cholerae infection_Homo sapiens_hsa051102.22092257
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.15262863
6Platelet activation_Homo sapiens_hsa046112.08595081
7Long-term potentiation_Homo sapiens_hsa047202.03726547
8Circadian entrainment_Homo sapiens_hsa047132.02369109
9Amphetamine addiction_Homo sapiens_hsa050312.00776493
10Renin secretion_Homo sapiens_hsa049241.79502252
11ECM-receptor interaction_Homo sapiens_hsa045121.78490099
12Olfactory transduction_Homo sapiens_hsa047401.76604701
13Oxidative phosphorylation_Homo sapiens_hsa001901.75092881
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.72046048
15Morphine addiction_Homo sapiens_hsa050321.66889379
16Glutamatergic synapse_Homo sapiens_hsa047241.65726928
17Dilated cardiomyopathy_Homo sapiens_hsa054141.59907515
18Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.58188804
19Rheumatoid arthritis_Homo sapiens_hsa053231.58035527
20Dopaminergic synapse_Homo sapiens_hsa047281.58010129
21Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.56606261
22Salivary secretion_Homo sapiens_hsa049701.55105950
23Long-term depression_Homo sapiens_hsa047301.53297328
24Alzheimers disease_Homo sapiens_hsa050101.51902777
25GABAergic synapse_Homo sapiens_hsa047271.48693250
26Calcium signaling pathway_Homo sapiens_hsa040201.48135259
27Taste transduction_Homo sapiens_hsa047421.47167558
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.46755602
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.42516819
30Serotonergic synapse_Homo sapiens_hsa047261.39784365
31Oxytocin signaling pathway_Homo sapiens_hsa049211.39494919
32Vascular smooth muscle contraction_Homo sapiens_hsa042701.37094619
33Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.33453219
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.30753026
35Focal adhesion_Homo sapiens_hsa045101.30543990
36Gastric acid secretion_Homo sapiens_hsa049711.29725893
37Cardiac muscle contraction_Homo sapiens_hsa042601.27239919
38Small cell lung cancer_Homo sapiens_hsa052221.26652531
39Axon guidance_Homo sapiens_hsa043601.24625324
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.19522944
41Melanoma_Homo sapiens_hsa052181.16999658
42Gap junction_Homo sapiens_hsa045401.15463705
43GnRH signaling pathway_Homo sapiens_hsa049121.14542815
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.14461708
45Glioma_Homo sapiens_hsa052141.12947924
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.12019046
47Melanogenesis_Homo sapiens_hsa049161.11063382
48Dorso-ventral axis formation_Homo sapiens_hsa043201.08614358
49Hedgehog signaling pathway_Homo sapiens_hsa043401.08267535
50Phagosome_Homo sapiens_hsa041451.06735066
51Primary bile acid biosynthesis_Homo sapiens_hsa001201.05581537
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04410030
53African trypanosomiasis_Homo sapiens_hsa051431.01438877
54Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.00130231
55Rap1 signaling pathway_Homo sapiens_hsa040151.00106548
56Cholinergic synapse_Homo sapiens_hsa047250.98182255
57Insulin secretion_Homo sapiens_hsa049110.98143081
58Parkinsons disease_Homo sapiens_hsa050120.95743737
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.95531726
60Aldosterone synthesis and secretion_Homo sapiens_hsa049250.93989553
61Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.93753456
62AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.93194352
63Protein digestion and absorption_Homo sapiens_hsa049740.92666427
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92657941
65Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92357089
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.92293246
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.91409917
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.90412179
69Phototransduction_Homo sapiens_hsa047440.90297061
70cAMP signaling pathway_Homo sapiens_hsa040240.89989766
71Ras signaling pathway_Homo sapiens_hsa040140.89713940
72Cocaine addiction_Homo sapiens_hsa050300.89348867
73Pathways in cancer_Homo sapiens_hsa052000.87854586
74Complement and coagulation cascades_Homo sapiens_hsa046100.85308787
75TGF-beta signaling pathway_Homo sapiens_hsa043500.84751757
76Ovarian steroidogenesis_Homo sapiens_hsa049130.84637662
77Amoebiasis_Homo sapiens_hsa051460.84625039
78ABC transporters_Homo sapiens_hsa020100.82426550
79Sphingolipid metabolism_Homo sapiens_hsa006000.82330946
80ErbB signaling pathway_Homo sapiens_hsa040120.79809510
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.78866671
82Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78805458
83Tryptophan metabolism_Homo sapiens_hsa003800.78680592
84Linoleic acid metabolism_Homo sapiens_hsa005910.77462060
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76643266
86Adherens junction_Homo sapiens_hsa045200.76510484
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76160476
88Nitrogen metabolism_Homo sapiens_hsa009100.76153152
89Glycerolipid metabolism_Homo sapiens_hsa005610.74987591
90Hippo signaling pathway_Homo sapiens_hsa043900.74355982
91Proteoglycans in cancer_Homo sapiens_hsa052050.73920225
92Malaria_Homo sapiens_hsa051440.73694432
93Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72286951
94Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.72103990
95Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70692238
96Circadian rhythm_Homo sapiens_hsa047100.70361691
97Estrogen signaling pathway_Homo sapiens_hsa049150.70209863
98PI3K-Akt signaling pathway_Homo sapiens_hsa041510.70067714
99Basal cell carcinoma_Homo sapiens_hsa052170.69894700
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69394757
101Wnt signaling pathway_Homo sapiens_hsa043100.68727098
102Leukocyte transendothelial migration_Homo sapiens_hsa046700.68723583
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.68102083
104N-Glycan biosynthesis_Homo sapiens_hsa005100.67586683
105Phenylalanine metabolism_Homo sapiens_hsa003600.64369972
106PPAR signaling pathway_Homo sapiens_hsa033200.63489328
107Renin-angiotensin system_Homo sapiens_hsa046140.62883295
108MicroRNAs in cancer_Homo sapiens_hsa052060.62736956
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.62725849
110MAPK signaling pathway_Homo sapiens_hsa040100.62250932
111Tight junction_Homo sapiens_hsa045300.61295854
112Huntingtons disease_Homo sapiens_hsa050160.61212176
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.61017701
114Thyroid hormone synthesis_Homo sapiens_hsa049180.58910186
115Mineral absorption_Homo sapiens_hsa049780.58768108
116Butanoate metabolism_Homo sapiens_hsa006500.57972513
117Bladder cancer_Homo sapiens_hsa052190.57884770
118Chemical carcinogenesis_Homo sapiens_hsa052040.53903718
119Retinol metabolism_Homo sapiens_hsa008300.50254229
120Sulfur metabolism_Homo sapiens_hsa009200.48029726
121Arachidonic acid metabolism_Homo sapiens_hsa005900.47939847
122Fatty acid elongation_Homo sapiens_hsa000620.47794567
123Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46400704
124Glutathione metabolism_Homo sapiens_hsa004800.44627223
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.44324238
126p53 signaling pathway_Homo sapiens_hsa041150.42782742
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42764782
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40678826
129Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.39455970
130Ether lipid metabolism_Homo sapiens_hsa005650.39438738
131Salmonella infection_Homo sapiens_hsa051320.38800261
132Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38216418
133Pancreatic secretion_Homo sapiens_hsa049720.37451794
134SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36416022
135Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36159057
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36016378
137Phospholipase D signaling pathway_Homo sapiens_hsa040720.35974595
138Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35504086
139Endometrial cancer_Homo sapiens_hsa052130.34782245
140Prion diseases_Homo sapiens_hsa050200.34408251
141VEGF signaling pathway_Homo sapiens_hsa043700.33004412

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