FAM43A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lymph vessel development (GO:0001945)7.42254671
2vascular endothelial growth factor signaling pathway (GO:0038084)6.01711843
3wound healing, spreading of epidermal cells (GO:0035313)5.08861883
4cellular response to vascular endothelial growth factor stimulus (GO:0035924)5.06917969
5regulation of integrin activation (GO:0033623)4.67375344
6morphogenesis of an endothelium (GO:0003159)4.60497783
7endothelial tube morphogenesis (GO:0061154)4.60497783
8endothelial cell chemotaxis (GO:0035767)4.13399516
9lymphangiogenesis (GO:0001946)4.09056258
10positive regulation of endothelial cell differentiation (GO:0045603)4.02172554
11basement membrane organization (GO:0071711)4.00526986
12vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.96541968
13angiogenesis involved in wound healing (GO:0060055)3.95390256
14response to laminar fluid shear stress (GO:0034616)3.88155616
15cell migration involved in heart development (GO:0060973)3.83520946
16endothelium development (GO:0003158)3.83382109
17retina vasculature morphogenesis in camera-type eye (GO:0061299)3.73106165
18positive regulation of blood vessel endothelial cell migration (GO:0043536)3.73093608
19blood vessel maturation (GO:0001955)3.69430686
20wound healing, spreading of cells (GO:0044319)3.68030327
21negative regulation of cell junction assembly (GO:1901889)3.65183289
22negative regulation of adherens junction organization (GO:1903392)3.65183289
23negative regulation of focal adhesion assembly (GO:0051895)3.65183289
24regulation of apoptotic cell clearance (GO:2000425)3.63484994
25establishment of endothelial barrier (GO:0061028)3.57863844
26regulation of blood vessel endothelial cell migration (GO:0043535)3.52486428
27negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.50946961
28glomerular filtration (GO:0003094)3.43332131
29apoptotic cell clearance (GO:0043277)3.42327467
30regulation of cell migration involved in sprouting angiogenesis (GO:0090049)3.41366906
31response to fluid shear stress (GO:0034405)3.38700389
32mRNA transcription (GO:0009299)3.35254585
33negative regulation of stress fiber assembly (GO:0051497)3.34973442
34positive regulation of Rap GTPase activity (GO:0032854)3.32876028
35patterning of blood vessels (GO:0001569)3.32063612
36blood vessel endothelial cell migration (GO:0043534)3.29475848
37positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.27289687
38renal filtration (GO:0097205)3.27018398
39positive regulation of odontogenesis (GO:0042482)3.26407205
40mRNA transcription from RNA polymerase II promoter (GO:0042789)3.23600286
41positive regulation of interleukin-8 secretion (GO:2000484)3.21366407
42cellular extravasation (GO:0045123)3.19513612
43cellular response to fluid shear stress (GO:0071498)3.15721304
44artery development (GO:0060840)3.15109943
45regulation of glomerular filtration (GO:0003093)3.11469235
46endothelial cell morphogenesis (GO:0001886)3.10418658
47positive regulation of vasculogenesis (GO:2001214)3.08153513
48negative regulation of blood vessel endothelial cell migration (GO:0043537)3.03726538
49positive regulation of endothelial cell migration (GO:0010595)3.03643681
50negative regulation of endothelial cell migration (GO:0010596)3.01748818
51protein localization to endosome (GO:0036010)3.01664709
52antigen processing and presentation of endogenous antigen (GO:0019883)2.99606117
53positive regulation of histone deacetylation (GO:0031065)2.99119916
54negative regulation of fatty acid transport (GO:2000192)2.97647482
55hyaluronan catabolic process (GO:0030214)2.96346808
56protein heterotrimerization (GO:0070208)2.94083387
57embryonic process involved in female pregnancy (GO:0060136)2.93328728
58negative regulation of chondrocyte differentiation (GO:0032331)2.89543600
59positive regulation of fibroblast migration (GO:0010763)2.87028461
60positive regulation of endothelial cell apoptotic process (GO:2000353)2.86740980
61vasculogenesis (GO:0001570)2.85202288
62cell migration involved in sprouting angiogenesis (GO:0002042)2.83999997
63cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.83047555
64antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.82173385
65antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.82173385
66negative regulation of vascular permeability (GO:0043116)2.81445449
67heart trabecula formation (GO:0060347)2.80849926
68regulation of dendritic cell antigen processing and presentation (GO:0002604)2.78775677
69regulation of endothelial cell migration (GO:0010594)2.77931627
70B cell receptor signaling pathway (GO:0050853)2.77330855
71endocardial cushion development (GO:0003197)2.76761097
72negative regulation of erythrocyte differentiation (GO:0045647)2.76613811
73endothelial cell proliferation (GO:0001935)2.74394115
74endothelial cell migration (GO:0043542)2.73373696
75leukocyte tethering or rolling (GO:0050901)2.71305577
76sprouting angiogenesis (GO:0002040)2.70667360
77regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)2.70337562
78apoptotic process involved in morphogenesis (GO:0060561)2.67725085
79positive regulation of cartilage development (GO:0061036)2.66663662
80renal system development (GO:0072001)2.66601976
81regulation of endothelial cell differentiation (GO:0045601)2.65896588
82positive regulation of cell adhesion mediated by integrin (GO:0033630)2.64031628
83trabecula morphogenesis (GO:0061383)2.63667166
84negative regulation of nitric-oxide synthase activity (GO:0051001)2.63238894
85surfactant homeostasis (GO:0043129)2.62836643
86positive regulation of receptor recycling (GO:0001921)2.62448195
87regulation of SMAD protein import into nucleus (GO:0060390)2.61241730
88coronary vasculature morphogenesis (GO:0060977)2.60432534
89endothelial cell differentiation (GO:0045446)2.60397608
90positive regulation of urine volume (GO:0035810)2.59723162
91positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)2.59558301
92regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.59127200
93chondrocyte proliferation (GO:0035988)2.58369630
94angiogenesis (GO:0001525)2.57645331
95negative regulation of platelet activation (GO:0010544)2.57248537
96regulation of Rap GTPase activity (GO:0032317)2.57137121
97regulation of endothelial cell chemotaxis (GO:2001026)2.57059151
98maternal placenta development (GO:0001893)2.55205133
99venous blood vessel morphogenesis (GO:0048845)2.55033869
100neuron remodeling (GO:0016322)2.54657286
101negative regulation of granulocyte differentiation (GO:0030853)2.54582072
102replacement ossification (GO:0036075)2.54062957
103endochondral ossification (GO:0001958)2.54062957
104plasma membrane repair (GO:0001778)2.53600084
105negative regulation of endothelial cell proliferation (GO:0001937)2.52233863
106definitive hemopoiesis (GO:0060216)2.50785218
107cell proliferation involved in metanephros development (GO:0072203)2.49672634
108positive regulation of chondrocyte differentiation (GO:0032332)2.49518226
109negative regulation of heart growth (GO:0061117)2.49372160
110negative regulation of cardiac muscle tissue growth (GO:0055022)2.49372160
111substrate-dependent cell migration (GO:0006929)2.47499343
112positive regulation of epithelial cell migration (GO:0010634)2.47406911
113cell-substrate junction assembly (GO:0007044)2.47272400
114platelet-derived growth factor receptor signaling pathway (GO:0048008)2.47171392
115interleukin-6-mediated signaling pathway (GO:0070102)2.46883630
116atrioventricular valve morphogenesis (GO:0003181)2.46327596
117positive regulation of lamellipodium assembly (GO:0010592)2.45980811
118skin morphogenesis (GO:0043589)2.45967816
119endothelial cell development (GO:0001885)2.45473294
120regulation of p38MAPK cascade (GO:1900744)2.45073212
121muscle organ morphogenesis (GO:0048644)2.44358140
122regulation of interferon-beta biosynthetic process (GO:0045357)2.44357713
123endodermal cell differentiation (GO:0035987)2.43693448
124regulation of vasculogenesis (GO:2001212)2.43221709
125transcytosis (GO:0045056)2.42589817
126negative regulation of interleukin-8 production (GO:0032717)2.42399856
127negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.42229440
128negative regulation of cell-matrix adhesion (GO:0001953)2.41251601
129positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.40907381
130negative regulation of DNA biosynthetic process (GO:2000279)2.40513152
131embryonic placenta development (GO:0001892)2.40370104
132negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.40333229
133regulation of macrophage chemotaxis (GO:0010758)2.40025507
134germ cell migration (GO:0008354)2.39115468
135regulation of cartilage development (GO:0061035)2.38615526
136ovulation from ovarian follicle (GO:0001542)2.38002079
137cellular response to zinc ion (GO:0071294)2.37967291
138blood vessel remodeling (GO:0001974)2.37506914
139glomerular visceral epithelial cell development (GO:0072015)2.37105475
140negative regulation of cell-substrate adhesion (GO:0010812)2.36585530
141trabecula formation (GO:0060343)2.36575132
142positive regulation of SMAD protein import into nucleus (GO:0060391)2.36363080
143Notch signaling involved in heart development (GO:0061314)2.36247215
144semaphorin-plexin signaling pathway (GO:0071526)2.35953635
145positive regulation of astrocyte differentiation (GO:0048711)2.35879308
146anatomical structure maturation (GO:0071695)2.35755954
147radial glial cell differentiation (GO:0060019)2.35705273
148adherens junction assembly (GO:0034333)2.35070196
149negative regulation of epithelial cell migration (GO:0010633)2.35067927
150regulation of chondrocyte differentiation (GO:0032330)2.34847709
151embryonic heart tube development (GO:0035050)2.34686124
152negative regulation of cell fate specification (GO:0009996)2.34590612
153stress fiber assembly (GO:0043149)2.34423918
154positive regulation of lipid kinase activity (GO:0090218)2.34043224
155detection of other organism (GO:0098543)2.33660255
156negative regulation of cartilage development (GO:0061037)2.32746359
157negative regulation of angiogenesis (GO:0016525)2.31884188
158positive regulation of collagen biosynthetic process (GO:0032967)2.29217050
159response to magnesium ion (GO:0032026)2.29000490

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.15156754
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.13729016
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.24407685
4ELK3_25401928_ChIP-Seq_HUVEC_Human2.89408961
5* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.68410509
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.68126167
7MYC_22102868_ChIP-Seq_BL_Human2.59125551
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.56559434
9RARG_19884340_ChIP-ChIP_MEFs_Mouse2.49569426
10* VDR_21846776_ChIP-Seq_THP-1_Human2.47872592
11KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.47699701
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.47699701
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.47699701
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.44756043
15PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.39493366
16CLOCK_20551151_ChIP-Seq_293T_Human2.31799104
17STAT6_21828071_ChIP-Seq_BEAS2B_Human2.19312165
18TCF7_22412390_ChIP-Seq_EML_Mouse2.14435362
19SCL_19346495_ChIP-Seq_HPC-7_Human2.08962430
20GATA2_21666600_ChIP-Seq_HMVEC_Human2.07471358
21KDM2B_26808549_Chip-Seq_DND41_Human2.02459901
22NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.94648367
23LXR_22292898_ChIP-Seq_THP-1_Human1.89765000
24TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.89206854
25HIF1A_21447827_ChIP-Seq_MCF-7_Human1.88811369
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.88301328
27STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.87805324
28ZNF263_19887448_ChIP-Seq_K562_Human1.87355587
29KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.85917945
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.84074071
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.81020455
32RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.80728823
33PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.74207378
34ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.67160751
35* VDR_24763502_ChIP-Seq_THP-1_Human1.64294211
36EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.63317653
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.62052816
38POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.62023311
39FOXO3_23340844_ChIP-Seq_DLD1_Human1.61639450
40* MAF_26560356_Chip-Seq_TH1_Human1.60723695
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.57854949
42IRF8_22096565_ChIP-ChIP_GC-B_Human1.56209358
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.55386045
44RUNX_20019798_ChIP-Seq_JUKART_Human1.53818166
45TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.53658239
46KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52158227
47TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51805273
48RACK7_27058665_Chip-Seq_MCF-7_Human1.51162166
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.49696398
50GATA1_19941826_ChIP-Seq_K562_Human1.49601133
51ESR1_21235772_ChIP-Seq_MCF-7_Human1.48805479
52THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.47761278
53KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47223604
54* TBX20_22328084_ChIP-Seq_HEART_Mouse1.46421718
55* TBX20_22080862_ChIP-Seq_HEART_Mouse1.46421718
56* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.44602429
57MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.44228828
58SPI1_23127762_ChIP-Seq_K562_Human1.43584780
59KDM2B_26808549_Chip-Seq_JURKAT_Human1.42563898
60* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.39639412
61CDX2_20551321_ChIP-Seq_CACO-2_Human1.37907472
62UTX_26944678_Chip-Seq_JUKART_Human1.34117924
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.33761493
64* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.32837793
65MYB_21317192_ChIP-Seq_ERMYB_Mouse1.32794073
66* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.31084532
67* KDM2B_26808549_Chip-Seq_K562_Human1.29997001
68NCOR1_26117541_ChIP-Seq_K562_Human1.28524368
69TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.28218444
70WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.27749146
71BRD4_27068464_Chip-Seq_AML-cells_Mouse1.27337426
72ZFP281_18757296_ChIP-ChIP_E14_Mouse1.27249046
73IRF8_27001747_Chip-Seq_BMDM_Mouse1.26927295
74NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.24952989
75VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.24211957
76STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22063407
77SOX9_24532713_ChIP-Seq_HFSC_Mouse1.21887369
78IRF8_21731497_ChIP-ChIP_J774_Mouse1.21402596
79TCF3_18692474_ChIP-Seq_MEFs_Mouse1.21136697
80* UBF1/2_26484160_Chip-Seq_HMECs_Human1.20563120
81ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20092292
82P300_27058665_Chip-Seq_ZR-75-30cells_Human1.19386032
83* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.19200841
84* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.14577427
85KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.13780048
86CTCF_27219007_Chip-Seq_ERYTHROID_Human1.13330574
87PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11352994
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10506239
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09587606
90TP53_22127205_ChIP-Seq_IMR90_Human1.09443779
91BRD4_25478319_ChIP-Seq_HGPS_Human1.08350195
92ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07378009
93RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.07070441
94EZH2_18974828_ChIP-Seq_MESCs_Mouse1.06924492
95RNF2_18974828_ChIP-Seq_MESCs_Mouse1.06924492
96SMC1_22415368_ChIP-Seq_MEFs_Mouse1.06417883
97SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.05583234
98SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.05356066
99WT1_19549856_ChIP-ChIP_CCG9911_Human1.04722728
100* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04171122
101RUNX1_27514584_Chip-Seq_MCF-7_Human1.03265607
102FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.03162136
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02889270
104NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02668919
105FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.02267292
106Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.01824138
107* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.01742849
108TP53_20018659_ChIP-ChIP_R1E_Mouse1.01047601
109SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.00790461
110* ATF3_27146783_Chip-Seq_COLON_Human1.00715783
111SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.00384526
112SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.00384526
113RUNX1_22412390_ChIP-Seq_EML_Mouse1.00238460
114P63_26484246_Chip-Seq_KERATINOCYTES_Human0.99860528
115SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.98597676
116SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97904855
117EP300_21415370_ChIP-Seq_HL-1_Mouse0.97767699
118TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97719699
119UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96691773
120SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.94366986
121CJUN_26792858_Chip-Seq_BT549_Human0.94135908
122JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92502816
123EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.92441714
124GATA1_19941827_ChIP-Seq_MEL_Mouse0.86144361
125* TP53_23651856_ChIP-Seq_MEFs_Mouse0.85938717

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010368_abnormal_lymphatic_system4.44406959
2MP0001879_abnormal_lymphatic_vessel4.37787079
3MP0008438_abnormal_cutaneous_collagen3.20839809
4MP0004272_abnormal_basement_membrane3.10958828
5MP0006054_spinal_hemorrhage3.08026227
6MP0005167_abnormal_blood-brain_barrier3.05958398
7MP0003705_abnormal_hypodermis_morpholog2.71400815
8MP0009278_abnormal_bone_marrow2.60901739
9MP0003279_aneurysm2.51628513
10MP0003724_increased_susceptibility_to2.41574242
11MP0003300_gastrointestinal_ulcer2.20102008
12MP0003303_peritoneal_inflammation2.19365731
13MP0002138_abnormal_hepatobiliary_system2.15633253
14MP0003828_pulmonary_edema2.07439396
15MP0003566_abnormal_cell_adhesion2.02043868
16MP0005275_abnormal_skin_tensile1.92402283
17MP0005257_abnormal_intraocular_pressure1.92233503
18MP0004084_abnormal_cardiac_muscle1.89315043
19MP0000767_abnormal_smooth_muscle1.85915764
20MP0000013_abnormal_adipose_tissue1.76933263
21MP0005409_darkened_coat_color1.69396365
22MP0004233_abnormal_muscle_weight1.61807090
23MP0005595_abnormal_vascular_smooth1.58791127
24MP0001790_abnormal_immune_system1.51848456
25MP0005387_immune_system_phenotype1.51848456
26MP0003191_abnormal_cellular_cholesterol1.49052370
27MP0005023_abnormal_wound_healing1.48999742
28MP0002933_joint_inflammation1.48579847
29MP0005076_abnormal_cell_differentiation1.48578821
30MP0000249_abnormal_blood_vessel1.47110387
31MP0010030_abnormal_orbit_morphology1.46727963
32MP0004808_abnormal_hematopoietic_stem1.46444706
33MP0005623_abnormal_meninges_morphology1.45188792
34MP0001958_emphysema1.42083625
35MP0003045_fibrosis1.42073300
36MP0000685_abnormal_immune_system1.42065939
37MP0000343_altered_response_to1.41938424
38MP0003091_abnormal_cell_migration1.40944043
39MP0010352_gastrointestinal_tract_polyps1.40681050
40MP0010630_abnormal_cardiac_muscle1.38675965
41MP0000465_gastrointestinal_hemorrhage1.37104857
42MP0002925_abnormal_cardiovascular_devel1.34332461
43MP0001851_eye_inflammation1.33734566
44MP0008004_abnormal_stomach_pH1.33516265
45MP0001800_abnormal_humoral_immune1.33087994
46MP0000750_abnormal_muscle_regeneration1.32958841
47MP0003941_abnormal_skin_development1.31462974
48MP0001348_abnormal_lacrimal_gland1.28274090
49MP0000733_abnormal_muscle_development1.27572373
50MP0002128_abnormal_blood_circulation1.25611763
51MP0001849_ear_inflammation1.23323631
52MP0002060_abnormal_skin_morphology1.22925825
53MP0000003_abnormal_adipose_tissue1.21620686
54MP0002796_impaired_skin_barrier1.16957502
55MP0001614_abnormal_blood_vessel1.16632173
56MP0001873_stomach_inflammation1.16623959
57MP0004215_abnormal_myocardial_fiber1.12179458
58MP0005503_abnormal_tendon_morphology1.10943185
59MP0002452_abnormal_antigen_presenting1.10932789
60MP0002396_abnormal_hematopoietic_system1.09230862
61MP0004036_abnormal_muscle_relaxation1.08412256
62MP0000751_myopathy1.08124620
63MP0001915_intracranial_hemorrhage1.05843130
64MP0004858_abnormal_nervous_system1.04677027
65MP0002295_abnormal_pulmonary_circulatio1.02393357
66MP0005330_cardiomyopathy1.01385703
67MP0009840_abnormal_foam_cell1.01346485
68MP0002166_altered_tumor_susceptibility1.00858609
69MP0005501_abnormal_skin_physiology1.00437332
70MP0004947_skin_inflammation1.00417322
71MP0005508_abnormal_skeleton_morphology1.00374262
72MP0005000_abnormal_immune_tolerance1.00298036
73MP0004484_altered_response_of1.00219298
74MP0001533_abnormal_skeleton_physiology0.99169562
75MP0002998_abnormal_bone_remodeling0.96032066
76MP0003763_abnormal_thymus_physiology0.95487271
77MP0005165_increased_susceptibility_to0.94007341
78MP0001835_abnormal_antigen_presentation0.93191430
79MP0001784_abnormal_fluid_regulation0.93149313
80MP0009333_abnormal_splenocyte_physiolog0.93098147
81MP0002332_abnormal_exercise_endurance0.92737192
82MP0004087_abnormal_muscle_fiber0.92471564
83MP0005385_cardiovascular_system_phenoty0.92376373
84MP0001544_abnormal_cardiovascular_syste0.92376373
85MP0005375_adipose_tissue_phenotype0.91842965
86MP0002127_abnormal_cardiovascular_syste0.91833863
87MP0003453_abnormal_keratinocyte_physiol0.91785615
88MP0006138_congestive_heart_failure0.91494985
89MP0000266_abnormal_heart_morphology0.91484787
90MP0004145_abnormal_muscle_electrophysio0.90382347
91MP0009384_cardiac_valve_regurgitation0.90334742
92MP0005670_abnormal_white_adipose0.89570525
93MP0002877_abnormal_melanocyte_morpholog0.89503351
94MP0003950_abnormal_plasma_membrane0.88438789
95MP0010155_abnormal_intestine_physiology0.88200040
96MP0005164_abnormal_response_to0.88110329
97MP0001545_abnormal_hematopoietic_system0.87894175
98MP0005397_hematopoietic_system_phenotyp0.87894175
99MP0004185_abnormal_adipocyte_glucose0.86665028
100MP0003436_decreased_susceptibility_to0.86108294
101MP0002108_abnormal_muscle_morphology0.85697366
102MP0003075_altered_response_to0.85673916
103MP0004510_myositis0.85085067
104MP0002837_dystrophic_cardiac_calcinosis0.84190728
105MP0003448_altered_tumor_morphology0.83335760
106MP0005390_skeleton_phenotype0.82797405
107MP0002420_abnormal_adaptive_immunity0.81389979
108MP0002405_respiratory_system_inflammati0.81161091
109MP0004883_abnormal_blood_vessel0.80485229
110MP0005025_abnormal_response_to0.79609217
111MP0008775_abnormal_heart_ventricle0.78907114
112MP0002896_abnormal_bone_mineralization0.78798117
113MP0001819_abnormal_immune_cell0.78372957
114MP0002932_abnormal_joint_morphology0.77812665
115MP0000858_altered_metastatic_potential0.77118177
116MP0002419_abnormal_innate_immunity0.76028285
117MP0000689_abnormal_spleen_morphology0.75769138
118MP0002148_abnormal_hypersensitivity_rea0.75330228
119MP0004130_abnormal_muscle_cell0.75222617
120MP0000467_abnormal_esophagus_morphology0.74641658
121MP0009931_abnormal_skin_appearance0.73522230
122MP0002723_abnormal_immune_serum0.72881281
123MP0001243_abnormal_dermal_layer0.72534977
124MP0001542_abnormal_bone_strength0.72068881
125MP0002086_abnormal_extraembryonic_tissu0.71858984
126MP0005197_abnormal_uvea_morphology0.71836943
127MP0010234_abnormal_vibrissa_follicle0.71047616
128MP0009250_abnormal_appendicular_skeleto0.69440759
129MP0009785_altered_susceptibility_to0.67155041
130MP0005166_decreased_susceptibility_to0.66025138
131MP0002092_abnormal_eye_morphology0.62857413
132MP0002133_abnormal_respiratory_system0.61513832

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.03713773
2Cerebral aneurysm (HP:0004944)4.80426054
3Broad metatarsal (HP:0001783)4.48205889
4Nonimmune hydrops fetalis (HP:0001790)3.81455153
5Shallow orbits (HP:0000586)3.70249482
6Premature rupture of membranes (HP:0001788)3.50991917
7Cellulitis (HP:0100658)3.39749993
8Cervical subluxation (HP:0003308)3.34600040
9Spontaneous hematomas (HP:0007420)3.32047786
10Peritonitis (HP:0002586)3.13514842
11Conjunctival telangiectasia (HP:0000524)3.12669399
12Abnormality of the nasal mucosa (HP:0000433)3.08030990
13Hematochezia (HP:0002573)3.06977465
14Aortic aneurysm (HP:0004942)2.95510000
15Increased connective tissue (HP:0009025)2.93361497
16Ankle contracture (HP:0006466)2.93264197
17Ventricular tachycardia (HP:0004756)2.89855090
18Lymphangioma (HP:0100764)2.87400889
19Polycythemia (HP:0001901)2.85128021
20Wrist flexion contracture (HP:0001239)2.85064067
21Colitis (HP:0002583)2.82934046
22Aortic dissection (HP:0002647)2.81629072
23Agammaglobulinemia (HP:0004432)2.76932572
24Overgrowth (HP:0001548)2.69753765
25Abnormality of the vasculature of the conjunctiva (HP:0008054)2.64101666
26Ulnar bowing (HP:0003031)2.60474539
27Vascular tortuosity (HP:0004948)2.58579563
28Aneurysm (HP:0002617)2.58179508
29Abnormality of the peritoneum (HP:0002585)2.53630674
30Emphysema (HP:0002097)2.49981758
31Increased variability in muscle fiber diameter (HP:0003557)2.49818987
32Verrucae (HP:0200043)2.46976705
33Papilloma (HP:0012740)2.46976705
34Atrophic scars (HP:0001075)2.44874498
35Mitral valve prolapse (HP:0001634)2.44515407
36Arterial tortuosity (HP:0005116)2.43854694
37Increased IgE level (HP:0003212)2.40324843
38Muscle fiber splitting (HP:0003555)2.38327022
39Aortic valve stenosis (HP:0001650)2.37487436
40Spondylolisthesis (HP:0003302)2.36227834
41Hypoplastic ischia (HP:0003175)2.36102171
42Distal lower limb muscle weakness (HP:0009053)2.33063912
43Spinal rigidity (HP:0003306)2.29729648
44Skull defect (HP:0001362)2.29012255
45Trismus (HP:0000211)2.28563841
46Abnormality of skeletal muscle fiber size (HP:0012084)2.28298602
47Gastrointestinal stroma tumor (HP:0100723)2.27966278
48Asymmetric septal hypertrophy (HP:0001670)2.25613884
49Cerebral hemorrhage (HP:0001342)2.18614240
50Tetraparesis (HP:0002273)2.18181232
51Bowed forearm bones (HP:0003956)2.18044151
52Bowing of the arm (HP:0006488)2.18044151
53Flexion contracture of toe (HP:0005830)2.16579042
54Joint contractures involving the joints of the feet (HP:0100492)2.16579042
55Gastrointestinal inflammation (HP:0004386)2.16412268
56Bladder diverticulum (HP:0000015)2.15061122
57Soft skin (HP:0000977)2.14611895
58Broad face (HP:0000283)2.14131741
59Hyporeflexia of lower limbs (HP:0002600)2.11139164
60Blue sclerae (HP:0000592)2.09946492
61Fragile skin (HP:0001030)2.07739853
62Inflammation of the large intestine (HP:0002037)2.06827779
63Joint laxity (HP:0001388)2.06033203
64Venous insufficiency (HP:0005293)2.05626486
65Absent hand (HP:0004050)2.04514616
66Coxa vara (HP:0002812)2.04051645
67Visceral angiomatosis (HP:0100761)2.03000380
68Abnormal vertebral ossification (HP:0100569)2.01864853
69Venous abnormality (HP:0002624)2.01116744
70Thin bony cortex (HP:0002753)1.99129927
71Pulmonary hypertension (HP:0002092)1.98713830
72Abnormality of the ischium (HP:0003174)1.98605761
73Mucosal telangiectasiae (HP:0100579)1.96579215
74Hemangiomatosis (HP:0007461)1.95707301
75Follicular hyperkeratosis (HP:0007502)1.95479974
76Short nail (HP:0001799)1.95274442
77Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.94635140
78Adactyly (HP:0009776)1.93123319
79Stroke (HP:0001297)1.92980526
80Vertebral clefting (HP:0008428)1.92871674
81Portal hypertension (HP:0001409)1.91924997
82Mitral regurgitation (HP:0001653)1.91271473
83Neonatal death (HP:0003811)1.91007242
84Dysostosis multiplex (HP:0000943)1.89275948
85Systemic lupus erythematosus (HP:0002725)1.88446520
86Esophageal varix (HP:0002040)1.87953371
87Elbow flexion contracture (HP:0002987)1.86961777
88Hip contracture (HP:0003273)1.86745688
89Vertebral compression fractures (HP:0002953)1.86591090
90Abnormality of dentin (HP:0010299)1.85401018
91Hemorrhage of the eye (HP:0011885)1.85001267
92Joint stiffness (HP:0001387)1.83960169
93Impaired platelet aggregation (HP:0003540)1.83480689
94Abnormal platelet function (HP:0011869)1.83480689
95Dilatation of the ascending aorta (HP:0005111)1.83248047
96Genu recurvatum (HP:0002816)1.82633463
97Type 1 muscle fiber predominance (HP:0003803)1.82084478
98Short hallux (HP:0010109)1.82056713
99Distal lower limb amyotrophy (HP:0008944)1.81545881
100Hydroureter (HP:0000072)1.79086857
101Recurrent bronchitis (HP:0002837)1.78878242
102Porencephaly (HP:0002132)1.77984979
103Mesangial abnormality (HP:0001966)1.77471940
104Reduced subcutaneous adipose tissue (HP:0003758)1.77411263
105Abnormality of the tricuspid valve (HP:0001702)1.77171944
106Menorrhagia (HP:0000132)1.76414013
107Slender build (HP:0001533)1.76081077
108Radial bowing (HP:0002986)1.76048613
109Difficulty climbing stairs (HP:0003551)1.75852798
110Mildly elevated creatine phosphokinase (HP:0008180)1.75796235
111Mitral stenosis (HP:0001718)1.75705327
112Striae distensae (HP:0001065)1.75521886
113Nasal polyposis (HP:0100582)1.75360085
114Camptodactyly of toe (HP:0001836)1.75093459
115Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.74726990
116Vertebral hypoplasia (HP:0008417)1.74726990
117Aortic regurgitation (HP:0001659)1.74292621
118Distal upper limb amyotrophy (HP:0007149)1.73709994
119Upper limb amyotrophy (HP:0009129)1.73709994
120Abnormality of the hepatic vasculature (HP:0006707)1.73460804
121Sudden death (HP:0001699)1.73019873
122Disproportionate tall stature (HP:0001519)1.72524872
123Hypotrichosis (HP:0001006)1.72258639
124Persistence of primary teeth (HP:0006335)1.72129955
125Aplasia/Hypoplasia of the hallux (HP:0008362)1.72015381
126Abnormality of the acetabulum (HP:0003170)1.71005372
127Wormian bones (HP:0002645)1.69845086
128Difficulty running (HP:0009046)1.69759541
129Abnormality of nail color (HP:0100643)1.69710629
130Right ventricular cardiomyopathy (HP:0011663)1.69141479
131Short clavicles (HP:0000894)1.68573217
132Mucopolysacchariduria (HP:0008155)1.68166520
133Urinary glycosaminoglycan excretion (HP:0003541)1.68166520
134Abnormal delayed hypersensitivity skin test (HP:0002963)1.67921141
135Ankyloglossia (HP:0010296)1.67658095
136Epistaxis (HP:0000421)1.67556450
137Interstitial pulmonary disease (HP:0006530)1.67038591
138Bicuspid aortic valve (HP:0001647)1.66754451
139Short 4th metacarpal (HP:0010044)1.66658626
140Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.66658626
141Abnormality of the sella turcica (HP:0002679)1.65412520
142Platyspondyly (HP:0000926)1.65274484
143Exercise-induced muscle cramps (HP:0003710)1.65072457
144Hand muscle atrophy (HP:0009130)1.62015755
145Ectopia lentis (HP:0001083)1.62012868
146Restrictive lung disease (HP:0002091)1.60607181
147Tibial bowing (HP:0002982)1.60414430

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE15.27098800
2KDR5.07142964
3ERN14.00717226
4TGFBR23.12472827
5MAP3K102.94447757
6TRIB32.79471427
7PKN22.30366605
8MAP4K12.28272661
9RIPK12.24440944
10BLK2.21768058
11EPHB12.21498145
12EEF2K2.00661070
13TTN1.91657387
14LRRK21.80091108
15PRPF4B1.64248133
16IRAK31.63751192
17PTK61.59824527
18DDR21.57519461
19BMX1.48228856
20MAPKAPK31.45378007
21TGFBR11.43743432
22CSK1.42732213
23STK101.42719350
24MAPK151.41349241
25EPHA21.40872316
26NEK91.33307369
27SIK11.33149623
28NTRK11.23804766
29GRK61.22769137
30CDK121.20180130
31GRK11.17968005
32SMG11.15867452
33PRKD21.09786580
34MATK1.09100836
35PDGFRA1.08376754
36CSF1R1.06649910
37MYLK1.05075849
38LATS21.03703453
39EPHA31.03326343
40PRKD31.02951288
41MAP2K30.97967268
42FLT30.97177537
43MET0.96298223
44TEC0.95205109
45ICK0.94197135
46JAK10.92844583
47ITK0.91335464
48EPHB20.90769202
49RPS6KA20.90041172
50PTK2B0.88861010
51PAK40.88615459
52IRAK40.86459283
53CAMK1D0.85699799
54PRKD10.84570665
55MAPK120.84061655
56PRKG20.82913908
57MOS0.82233718
58FES0.81501058
59PAK20.79601020
60DMPK0.78826349
61PDPK10.77119147
62MAP3K10.76515805
63DYRK1B0.74954817
64BTK0.74544819
65PIM10.74073081
66TBK10.73370447
67FER0.72357618
68JAK30.70274403
69MST1R0.70035137
70SIK20.68855989
71FGR0.68629549
72MAP3K110.68029916
73MAP2K10.67788187
74MAP3K130.67740026
75MAP3K30.67152254
76PTK20.66917821
77RPS6KB20.66699825
78CDK90.66589594
79CDC42BPA0.65665564
80HIPK20.63501661
81WNK10.63429664
82MAP3K70.62804888
83FGFR40.62084605
84HCK0.61143173
85PIK3CG0.60820285
86ZAP700.60631023
87TRPM70.60623663
88CAMK1G0.59704545
89CHUK0.58629132
90KIT0.57391891
91MAPK70.57189624
92MTOR0.55551440
93CLK10.54916448
94NLK0.54882358
95FGFR30.54102341
96MARK20.53744513
97TYRO30.53218991
98GSK3A0.52966136
99PRKCH0.52865357
100MAP3K60.50832269
101MAP3K140.50149734
102IKBKB0.49891687
103TAOK20.48015965
104JAK20.47583257
105CAMK40.46761751
106TYK20.45828048
107PDGFRB0.45603348
108ILK0.44977631
109LCK0.43869480
110MAPKAPK20.43395382
111TAOK10.43179878
112INSR0.42420175
113RPS6KA60.42085819
114PRKAA20.41754836
115PIM20.41718617
116DAPK30.41632264
117TESK10.41573099
118MAPK40.40516472
119MAP2K20.40295953
120CDK60.39380783
121EGFR0.37446358
122RPS6KA40.37321768
123ALK0.37297643
124IKBKE0.36710188
125STK380.36629948
126RPS6KC10.36039285
127RPS6KL10.36039285
128PDK10.34337643
129ABL20.33737875
130GRK50.33094715
131LYN0.32811754
132ROCK20.31578924
133ROCK10.28307492

Predicted pathways (KEGG)

RankGene SetZ-score
1Malaria_Homo sapiens_hsa051442.72505358
2B cell receptor signaling pathway_Homo sapiens_hsa046622.52600161
3AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.28753161
4Leukocyte transendothelial migration_Homo sapiens_hsa046702.20043265
5ECM-receptor interaction_Homo sapiens_hsa045122.15646150
6Focal adhesion_Homo sapiens_hsa045102.13424853
7Adherens junction_Homo sapiens_hsa045202.08746170
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.96928842
9Staphylococcus aureus infection_Homo sapiens_hsa051501.90032777
10Other glycan degradation_Homo sapiens_hsa005111.75631067
11Platelet activation_Homo sapiens_hsa046111.72435055
12Notch signaling pathway_Homo sapiens_hsa043301.70526015
13Primary immunodeficiency_Homo sapiens_hsa053401.69483767
14Osteoclast differentiation_Homo sapiens_hsa043801.62479670
15Small cell lung cancer_Homo sapiens_hsa052221.62018916
16Proteoglycans in cancer_Homo sapiens_hsa052051.60842326
17Leishmaniasis_Homo sapiens_hsa051401.52534859
18Hematopoietic cell lineage_Homo sapiens_hsa046401.50929880
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.49729968
20Amoebiasis_Homo sapiens_hsa051461.46791629
21Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.45107943
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.43236559
23African trypanosomiasis_Homo sapiens_hsa051431.42985227
24Chronic myeloid leukemia_Homo sapiens_hsa052201.41192390
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.40027197
26Toxoplasmosis_Homo sapiens_hsa051451.36692068
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.32894409
28Dilated cardiomyopathy_Homo sapiens_hsa054141.29367832
29Rap1 signaling pathway_Homo sapiens_hsa040151.26244398
30VEGF signaling pathway_Homo sapiens_hsa043701.23678416
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.21903131
32PI3K-Akt signaling pathway_Homo sapiens_hsa041511.21668297
33Pertussis_Homo sapiens_hsa051331.21193035
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.17050507
35Influenza A_Homo sapiens_hsa051641.16622058
36Complement and coagulation cascades_Homo sapiens_hsa046101.15248087
37TNF signaling pathway_Homo sapiens_hsa046681.14391665
38Pathways in cancer_Homo sapiens_hsa052001.14355782
39Viral myocarditis_Homo sapiens_hsa054161.12623868
40Insulin resistance_Homo sapiens_hsa049311.10131122
41Acute myeloid leukemia_Homo sapiens_hsa052211.08452885
42Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.07327062
43RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.06193280
44MicroRNAs in cancer_Homo sapiens_hsa052061.06049837
45HIF-1 signaling pathway_Homo sapiens_hsa040661.02968782
46Regulation of actin cytoskeleton_Homo sapiens_hsa048101.02719612
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99220473
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99015438
49Adipocytokine signaling pathway_Homo sapiens_hsa049200.98781697
50Shigellosis_Homo sapiens_hsa051310.98717111
51Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.98389369
52Chemokine signaling pathway_Homo sapiens_hsa040620.97967766
53GnRH signaling pathway_Homo sapiens_hsa049120.96298230
54Pancreatic cancer_Homo sapiens_hsa052120.96198907
55Jak-STAT signaling pathway_Homo sapiens_hsa046300.94238635
56HTLV-I infection_Homo sapiens_hsa051660.92981613
57Renal cell carcinoma_Homo sapiens_hsa052110.92764533
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91692607
59Allograft rejection_Homo sapiens_hsa053300.91183942
60Salmonella infection_Homo sapiens_hsa051320.90795951
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.90763291
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87791390
63Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87005021
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.86553747
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.85198885
66Basal cell carcinoma_Homo sapiens_hsa052170.84759627
67Bladder cancer_Homo sapiens_hsa052190.84597680
68Choline metabolism in cancer_Homo sapiens_hsa052310.83771636
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82897918
70Glioma_Homo sapiens_hsa052140.82511242
71Prolactin signaling pathway_Homo sapiens_hsa049170.82149821
72Ribosome_Homo sapiens_hsa030100.81438038
73Legionellosis_Homo sapiens_hsa051340.81413772
74Protein digestion and absorption_Homo sapiens_hsa049740.81264231
75TGF-beta signaling pathway_Homo sapiens_hsa043500.81249974
76Graft-versus-host disease_Homo sapiens_hsa053320.81090352
77Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77505293
78Caffeine metabolism_Homo sapiens_hsa002320.76605450
79Dorso-ventral axis formation_Homo sapiens_hsa043200.75222448
80Tuberculosis_Homo sapiens_hsa051520.75166386
81Colorectal cancer_Homo sapiens_hsa052100.74626120
82Viral carcinogenesis_Homo sapiens_hsa052030.74477457
83Endocytosis_Homo sapiens_hsa041440.72097059
84ErbB signaling pathway_Homo sapiens_hsa040120.71028685
85Axon guidance_Homo sapiens_hsa043600.70391691
86Ras signaling pathway_Homo sapiens_hsa040140.70359916
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.70116681
88Apoptosis_Homo sapiens_hsa042100.69779263
89Tight junction_Homo sapiens_hsa045300.69639858
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.68704052
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.68458591
92Endometrial cancer_Homo sapiens_hsa052130.67364450
93Autoimmune thyroid disease_Homo sapiens_hsa053200.65860184
94Non-small cell lung cancer_Homo sapiens_hsa052230.64954919
95Measles_Homo sapiens_hsa051620.64673543
96Estrogen signaling pathway_Homo sapiens_hsa049150.64539094
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63360673
98Herpes simplex infection_Homo sapiens_hsa051680.63176228
99Hippo signaling pathway_Homo sapiens_hsa043900.62404323
100Prostate cancer_Homo sapiens_hsa052150.62314880
101T cell receptor signaling pathway_Homo sapiens_hsa046600.61923380
102Hepatitis B_Homo sapiens_hsa051610.61728820
103Ovarian steroidogenesis_Homo sapiens_hsa049130.61600735
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.61520187
105Antigen processing and presentation_Homo sapiens_hsa046120.61375987
106MAPK signaling pathway_Homo sapiens_hsa040100.61015073
107Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60960258
108Lysosome_Homo sapiens_hsa041420.60924863
109Melanoma_Homo sapiens_hsa052180.60578925
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60508962
111FoxO signaling pathway_Homo sapiens_hsa040680.59293575
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.58633688
113Phagosome_Homo sapiens_hsa041450.57663946
114mTOR signaling pathway_Homo sapiens_hsa041500.57312790
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.54817509
116Hedgehog signaling pathway_Homo sapiens_hsa043400.54779848
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54779298
118Wnt signaling pathway_Homo sapiens_hsa043100.54774636
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.54432781
120Toll-like receptor signaling pathway_Homo sapiens_hsa046200.54227311
121Thyroid cancer_Homo sapiens_hsa052160.52973429
122Lysine degradation_Homo sapiens_hsa003100.52477506
123Hepatitis C_Homo sapiens_hsa051600.51915012
124Prion diseases_Homo sapiens_hsa050200.50817166

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