FAM53B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)7.01538853
2regulation of gamma-delta T cell differentiation (GO:0045586)5.79348244
3positive regulation of B cell differentiation (GO:0045579)5.68546687
4B cell receptor signaling pathway (GO:0050853)5.44617608
5regulation of gamma-delta T cell activation (GO:0046643)5.17058895
6positive regulation of histone deacetylation (GO:0031065)5.03068270
7natural killer cell differentiation (GO:0001779)5.01239995
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.88249168
9antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.88249168
10V(D)J recombination (GO:0033151)4.86927176
11negative regulation of erythrocyte differentiation (GO:0045647)4.72649535
12positive regulation by host of viral transcription (GO:0043923)4.61440351
13serine transport (GO:0032329)4.56131279
14L-serine transport (GO:0015825)4.47461940
15adaptation of signaling pathway (GO:0023058)4.44890959
16cellular hyperosmotic response (GO:0071474)4.43471038
17detection of other organism (GO:0098543)4.27384613
18regulation of histone H3-K9 methylation (GO:0051570)4.26768952
19Peyers patch development (GO:0048541)4.25349718
20mucosal-associated lymphoid tissue development (GO:0048537)4.25349718
21detection of bacterium (GO:0016045)4.24102731
22regulation of B cell differentiation (GO:0045577)4.22231185
23positive regulation by symbiont of host defense response (GO:0052509)4.17134109
24modulation by symbiont of host defense response (GO:0052031)4.17134109
25modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.17134109
26modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.17134109
27positive regulation by organism of defense response of other organism involved in symbiotic interact4.17134109
28modulation by symbiont of host immune response (GO:0052553)4.17134109
29antigen processing and presentation of endogenous antigen (GO:0019883)4.13568168
30protein-DNA complex disassembly (GO:0032986)4.10104215
31nucleosome disassembly (GO:0006337)4.10104215
32negative regulation of cell killing (GO:0031342)3.89801269
33negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.89801269
34negative regulation of phagocytosis (GO:0050765)3.85891072
35positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.80593214
36tolerance induction (GO:0002507)3.79550259
37positive regulation of protein deacetylation (GO:0090312)3.75208122
38macrophage activation involved in immune response (GO:0002281)3.73152310
39negative regulation of histone methylation (GO:0031061)3.70424798
40positive thymic T cell selection (GO:0045059)3.63159091
41negative regulation of lymphocyte mediated immunity (GO:0002707)3.61876925
42T cell homeostasis (GO:0043029)3.60097199
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.52619828
44T cell migration (GO:0072678)3.46074183
45detection of external biotic stimulus (GO:0098581)3.39122676
46negative regulation of granulocyte differentiation (GO:0030853)3.38885173
47positive regulation of gene expression, epigenetic (GO:0045815)3.38141105
48hepatocyte apoptotic process (GO:0097284)3.38104885
49germinal center formation (GO:0002467)3.34016855
50tachykinin receptor signaling pathway (GO:0007217)3.33504443
51negative regulation of leukocyte mediated immunity (GO:0002704)3.33327860
52regulation of superoxide anion generation (GO:0032928)3.32239318
53T cell selection (GO:0045058)3.31544713
54antigen processing and presentation via MHC class Ib (GO:0002475)3.30745528
55response to muramyl dipeptide (GO:0032495)3.30490429
56negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.29147813
57pentose-phosphate shunt (GO:0006098)3.27738746
58leukocyte aggregation (GO:0070486)3.27420503
59negative thymic T cell selection (GO:0045060)3.27347274
60antigen receptor-mediated signaling pathway (GO:0050851)3.26383205
61negative T cell selection (GO:0043383)3.23178439
62regulation of interferon-beta biosynthetic process (GO:0045357)3.20434305
63lymphocyte homeostasis (GO:0002260)3.17763000
64melanin biosynthetic process (GO:0042438)3.15783249
65regulation of interleukin-12 biosynthetic process (GO:0045075)3.12555540
66regulation of T-helper 2 cell differentiation (GO:0045628)3.09786871
67negative regulation of T cell mediated immunity (GO:0002710)3.06668658
68response to peptidoglycan (GO:0032494)3.06496996
69cellular extravasation (GO:0045123)3.05522616
70negative regulation of gene expression, epigenetic (GO:0045814)3.05235029
71negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.04202045
72negative regulation of bone resorption (GO:0045779)3.04112001
73chromatin silencing (GO:0006342)3.03816690
74regulation of mast cell degranulation (GO:0043304)3.03589428
75cellular response to zinc ion (GO:0071294)3.03537298
76DNA unwinding involved in DNA replication (GO:0006268)3.03067468
77regulation of leukocyte degranulation (GO:0043300)3.02362806
78detection of biotic stimulus (GO:0009595)3.02178639
79thymic T cell selection (GO:0045061)3.02038057
80immunoglobulin mediated immune response (GO:0016064)3.00515148
81regulation of granulocyte differentiation (GO:0030852)3.00114581
82regulation of B cell receptor signaling pathway (GO:0050855)2.99965735
83regulation of myeloid leukocyte mediated immunity (GO:0002886)2.96573705
84positive regulation of Rap GTPase activity (GO:0032854)2.94867935
85lens fiber cell development (GO:0070307)2.94787877
86embryonic hemopoiesis (GO:0035162)2.94164949
87positive regulation of lamellipodium assembly (GO:0010592)2.93857645
88histone H3-K36 demethylation (GO:0070544)2.92935820
89regulation of T cell tolerance induction (GO:0002664)2.88365496
90regulation of ARF protein signal transduction (GO:0032012)2.87757773
91regulation of extracellular matrix disassembly (GO:0010715)2.87256012
92melanin metabolic process (GO:0006582)2.86552276
93production of molecular mediator involved in inflammatory response (GO:0002532)2.86071472
94regulation of tolerance induction (GO:0002643)2.83981718
95natural killer cell activation (GO:0030101)2.82435005
96respiratory burst (GO:0045730)2.80176215
97germ cell migration (GO:0008354)2.79871419
98positive regulation of granulocyte differentiation (GO:0030854)2.78696841
99neutrophil activation (GO:0042119)2.78679739
100leukocyte homeostasis (GO:0001776)2.77541823
101cellular response to interleukin-15 (GO:0071350)2.76184290
102positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.75656950
103response to interleukin-15 (GO:0070672)2.75374798
104positive T cell selection (GO:0043368)2.75215831
105cellular response to osmotic stress (GO:0071470)2.74275667
106regulation of dendritic cell antigen processing and presentation (GO:0002604)2.74209864
107regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.73803732
108detection of molecule of bacterial origin (GO:0032490)2.73703017
109negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.72500151
110negative regulation of T-helper cell differentiation (GO:0045623)2.72500151
111regulation of necroptotic process (GO:0060544)2.72101162
112cortical actin cytoskeleton organization (GO:0030866)2.70801669
113myeloid cell activation involved in immune response (GO:0002275)2.70788269
114regulation of mast cell activation involved in immune response (GO:0033006)2.70332723
115negative regulation of toll-like receptor signaling pathway (GO:0034122)2.70272503
116T cell receptor signaling pathway (GO:0050852)2.70270128
1173-UTR-mediated mRNA stabilization (GO:0070935)2.70159379
118response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.69642705
119response to host immune response (GO:0052572)2.69642705
120activated T cell proliferation (GO:0050798)2.69452016
121regulation of Rap GTPase activity (GO:0032317)2.69287588
122NADPH regeneration (GO:0006740)2.68657001
123positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.68562441
124negative regulation of type 2 immune response (GO:0002829)2.66411345
125T cell costimulation (GO:0031295)2.65170623
126defense response to protozoan (GO:0042832)2.65114558
127regulation of alpha-beta T cell proliferation (GO:0046640)2.63909492
128negative regulation of interleukin-12 production (GO:0032695)2.63891342
129regulation of histone deacetylation (GO:0031063)2.63374528
130negative regulation of stress fiber assembly (GO:0051497)2.63083831
131regulation of antigen processing and presentation (GO:0002577)2.62776926
132B cell homeostasis (GO:0001782)2.61894348
133response to host (GO:0075136)2.61595647
134response to host defenses (GO:0052200)2.61595647
135response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.61595647
136erythrocyte differentiation (GO:0030218)2.61248653
137immune response-activating cell surface receptor signaling pathway (GO:0002429)2.60066518
138histone H3-K9 demethylation (GO:0033169)2.59998492
139response to type I interferon (GO:0034340)2.59540214
140type I interferon signaling pathway (GO:0060337)2.58965288
141cellular response to type I interferon (GO:0071357)2.58965288
142myeloid dendritic cell activation (GO:0001773)2.58537103
143lymphocyte costimulation (GO:0031294)2.57811360
144chromatin assembly (GO:0031497)2.56242778
145activation of JUN kinase activity (GO:0007257)2.55907220
146protein localization to endosome (GO:0036010)2.55262051
147establishment of endothelial barrier (GO:0061028)2.55022759
148vesicle targeting (GO:0006903)2.53458497
149JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.53228890
150positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.52636246
151neutrophil activation involved in immune response (GO:0002283)2.52177673
152mannose metabolic process (GO:0006013)2.49358584
153granulocyte activation (GO:0036230)2.49018955
154NIK/NF-kappaB signaling (GO:0038061)2.47818868
155positive regulation of erythrocyte differentiation (GO:0045648)2.47054583
156erythrocyte maturation (GO:0043249)2.47019479
157regulation of erythrocyte differentiation (GO:0045646)2.46705014
158positive regulation of interleukin-2 production (GO:0032743)2.46403902
159response to laminar fluid shear stress (GO:0034616)2.46379373
160positive regulation of lamellipodium organization (GO:1902745)2.46377756
161myeloid dendritic cell differentiation (GO:0043011)2.45868517

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.18751921
2MYC_22102868_ChIP-Seq_BL_Human4.36640900
3VDR_21846776_ChIP-Seq_THP-1_Human3.82521128
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.65470755
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.49955434
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.35643490
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.22843526
8SCL_19346495_ChIP-Seq_HPC-7_Human3.04931851
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.95080548
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.85330921
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.75872625
12RUNX_20019798_ChIP-Seq_JUKART_Human2.73126429
13TCF7_22412390_ChIP-Seq_EML_Mouse2.67328788
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.63793721
15E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.52633421
16MAF_26560356_Chip-Seq_TH1_Human2.51950032
17* UTX_26944678_Chip-Seq_JUKART_Human2.49570918
18* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.46950568
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.44537415
20KDM2B_26808549_Chip-Seq_DND41_Human2.44068291
21* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.40383901
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.37506997
23VDR_24763502_ChIP-Seq_THP-1_Human2.33408400
24FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.27323118
25MYB_26560356_Chip-Seq_TH2_Human2.23493261
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.19357891
27IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.13377373
28* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.12862384
29GATA1_22025678_ChIP-Seq_K562_Human2.12786336
30MYB_26560356_Chip-Seq_TH1_Human2.08150129
31BRD4_27068464_Chip-Seq_AML-cells_Mouse2.00698019
32* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.99866610
33SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89740208
34ELK3_25401928_ChIP-Seq_HUVEC_Human1.85054149
35SPI1_23127762_ChIP-Seq_K562_Human1.82840721
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.75847643
37GATA1_19941827_ChIP-Seq_MEL_Mouse1.74566386
38NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.74401554
39IRF8_27001747_Chip-Seq_BMDM_Mouse1.72689127
40MYB_21317192_ChIP-Seq_ERMYB_Mouse1.70823962
41RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.69002660
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67641569
43GATA1_19941826_ChIP-Seq_K562_Human1.67182844
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64027618
45STAT4_19710469_ChIP-ChIP_TH1__Mouse1.63039768
46IRF8_21731497_ChIP-ChIP_J774_Mouse1.62182755
47MAF_26560356_Chip-Seq_TH2_Human1.61025140
48CIITA_25753668_ChIP-Seq_RAJI_Human1.60930503
49NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.58660671
50* KDM2B_26808549_Chip-Seq_JURKAT_Human1.55092093
51GATA1_22383799_ChIP-Seq_G1ME_Mouse1.54074476
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48238381
53STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.48227184
54E2F4_17652178_ChIP-ChIP_JURKAT_Human1.46733294
55EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.45863101
56PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.45280270
57ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43396910
58LXR_22292898_ChIP-Seq_THP-1_Human1.43214533
59* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.42632263
60* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41438147
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.37943975
62SPI1_23547873_ChIP-Seq_NB4_Human1.34038594
63* GATA3_27048872_Chip-Seq_THYMUS_Human1.33414369
64TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.31300093
65* SA1_27219007_Chip-Seq_ERYTHROID_Human1.29629166
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.29310226
67* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.27752831
68IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.26690248
69PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26458344
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.24277857
71SMC4_20622854_ChIP-Seq_HELA_Human1.24171361
72* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22935311
73STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.21120728
74NCOR1_26117541_ChIP-Seq_K562_Human1.18462582
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16639439
76CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14786355
77ZFP281_18757296_ChIP-ChIP_E14_Mouse1.14073852
78RARG_19884340_ChIP-ChIP_MEFs_Mouse1.13749881
79LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.12535851
80FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12497077
81DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11610981
82CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09451854
83* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07629568
84GATA2_19941826_ChIP-Seq_K562_Human1.07096198
85RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.06954321
86CREB1_26743006_Chip-Seq_LNCaP_Human1.06661294
87* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04156811
88RUNX1_27514584_Chip-Seq_MCF-7_Human1.03927077
89ESR2_21235772_ChIP-Seq_MCF-7_Human1.03110899
90SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02954669
91ELF1_20517297_ChIP-Seq_JURKAT_Human1.02734543
92MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.02306312
93CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01388921
94PU_27001747_Chip-Seq_BMDM_Mouse0.99972865
95DROSHA_22980978_ChIP-Seq_HELA_Human0.99739501
96* KDM2B_26808549_Chip-Seq_K562_Human0.99117292
97* VDR_24787735_ChIP-Seq_THP-1_Human0.97610042
98TP63_17297297_ChIP-ChIP_HaCaT_Human0.96601687
99ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95899861
100TET1_21451524_ChIP-Seq_MESCs_Mouse0.95114175
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.94695922
102E2F1_21310950_ChIP-Seq_MCF-7_Human0.93794939
103RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.93790757
104SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.91681744
105BCOR_27268052_Chip-Seq_Bcells_Human0.89405798
106* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88083451
107FOXO3_23340844_ChIP-Seq_DLD1_Human0.87200343
108* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.87120615
109* RACK7_27058665_Chip-Seq_MCF-7_Human0.87061447
110P68_20966046_ChIP-Seq_HELA_Human0.87004149
111ETS1_22383799_ChIP-Seq_G1ME_Mouse0.86918748
112KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.86177561
113* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85765984
114* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84323054
115VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.84301969
116* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.84158130
117SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.84129781
118PU.1_20513432_ChIP-Seq_Bcells_Mouse0.84106249
119* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.83965827
120BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.83068282
121BCL6_27268052_Chip-Seq_Bcells_Human0.81869669
122GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.81581063
123* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.81255596
124CTCF_21964334_ChIP-Seq_BJAB-B_Human0.79243138
125SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.78848398
126* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.77986901

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000685_abnormal_immune_system3.52173832
2MP0002396_abnormal_hematopoietic_system2.98529879
3MP0003724_increased_susceptibility_to2.90882067
4MP0001800_abnormal_humoral_immune2.90532439
5MP0002166_altered_tumor_susceptibility2.77241814
6MP0009278_abnormal_bone_marrow2.62228065
7MP0005387_immune_system_phenotype2.58126474
8MP0001790_abnormal_immune_system2.58126474
9MP0003300_gastrointestinal_ulcer2.57007728
10MP0002398_abnormal_bone_marrow2.56058300
11MP0005451_abnormal_body_composition2.51115939
12MP0004808_abnormal_hematopoietic_stem2.36974234
13MP0008260_abnormal_autophagy2.36615314
14MP0001835_abnormal_antigen_presentation2.35791527
15MP0002452_abnormal_antigen_presenting2.34378502
16MP0003763_abnormal_thymus_physiology2.32235506
17MP0005671_abnormal_response_to2.26378900
18MP0003303_peritoneal_inflammation2.25853371
19MP0003172_abnormal_lysosome_physiology2.22313854
20MP0002420_abnormal_adaptive_immunity2.20530237
21MP0000689_abnormal_spleen_morphology2.19640552
22MP0001819_abnormal_immune_cell2.17013813
23MP0000703_abnormal_thymus_morphology2.15844709
24MP0002722_abnormal_immune_system2.13717881
25MP0003436_decreased_susceptibility_to2.12814523
26MP0000716_abnormal_immune_system2.10226394
27MP0002723_abnormal_immune_serum2.08562129
28MP0003656_abnormal_erythrocyte_physiolo2.02558416
29MP0006054_spinal_hemorrhage1.99900154
30MP0005397_hematopoietic_system_phenotyp1.92382869
31MP0001545_abnormal_hematopoietic_system1.92382869
32MP0003183_abnormal_peptide_metabolism1.85704095
33MP0002429_abnormal_blood_cell1.82808593
34MP0005000_abnormal_immune_tolerance1.81095237
35MP0009785_altered_susceptibility_to1.77971282
36MP0002006_tumorigenesis1.76143808
37MP0003191_abnormal_cellular_cholesterol1.70194341
38MP0005409_darkened_coat_color1.66631973
39MP0004947_skin_inflammation1.65004166
40MP0005025_abnormal_response_to1.63099626
41MP0001873_stomach_inflammation1.62878990
42MP0002405_respiratory_system_inflammati1.60584218
43MP0000465_gastrointestinal_hemorrhage1.56340331
44MP0003828_pulmonary_edema1.54108642
45MP0005464_abnormal_platelet_physiology1.53911650
46MP0010155_abnormal_intestine_physiology1.49774228
47MP0002095_abnormal_skin_pigmentation1.49440348
48MP0000372_irregular_coat_pigmentation1.47479677
49MP0010094_abnormal_chromosome_stability1.46517680
50MP0005076_abnormal_cell_differentiation1.45302938
51MP0008961_abnormal_basal_metabolism1.44608599
52MP0002419_abnormal_innate_immunity1.40381589
53MP0009840_abnormal_foam_cell1.40125943
54MP0002019_abnormal_tumor_incidence1.35735506
55MP0002148_abnormal_hypersensitivity_rea1.32197112
56MP0004185_abnormal_adipocyte_glucose1.31987246
57MP0003705_abnormal_hypodermis_morpholog1.30656919
58MP0003690_abnormal_glial_cell1.29995629
59MP0003866_abnormal_defecation1.29246232
60MP0000490_abnormal_crypts_of1.27914363
61MP0009333_abnormal_splenocyte_physiolog1.27294392
62MP0010352_gastrointestinal_tract_polyps1.24984423
63MP0004381_abnormal_hair_follicle1.24760382
64MP0002933_joint_inflammation1.20335613
65MP0002998_abnormal_bone_remodeling1.18358343
66MP0002132_abnormal_respiratory_system1.18227586
67MP0005670_abnormal_white_adipose1.15771235
68MP0000858_altered_metastatic_potential1.14232476
69MP0005666_abnormal_adipose_tissue1.12782340
70MP0010307_abnormal_tumor_latency1.12345067
71MP0000371_diluted_coat_color1.08175716
72MP0004130_abnormal_muscle_cell1.07634553
73MP0005171_absent_coat_pigmentation1.06937641
74MP0003111_abnormal_nucleus_morphology1.05482384
75MP0005174_abnormal_tail_pigmentation1.04470744
76MP0001845_abnormal_inflammatory_respons1.03994062
77MP0003045_fibrosis1.03508107
78MP0000015_abnormal_ear_pigmentation1.01778163
79MP0003453_abnormal_keratinocyte_physiol1.01537949
80MP0003077_abnormal_cell_cycle0.99933402
81MP0004147_increased_porphyrin_level0.99720435
82MP0005375_adipose_tissue_phenotype0.97121567
83MP0002877_abnormal_melanocyte_morpholog0.93446392
84MP0006082_CNS_inflammation0.92704933
85MP0005166_decreased_susceptibility_to0.92317398
86MP0008469_abnormal_protein_level0.91691252
87MP0001879_abnormal_lymphatic_vessel0.91252453
88MP0002009_preneoplasia0.89991523
89MP0003011_delayed_dark_adaptation0.89687744
90MP0003566_abnormal_cell_adhesion0.88052480
91MP0004510_myositis0.87589973
92MP0003329_amyloid_beta_deposits0.86243978
93MP0005075_abnormal_melanosome_morpholog0.85926469
94MP0004883_abnormal_blood_vessel0.84807841
95MP0000604_amyloidosis0.84606501
96MP0002970_abnormal_white_adipose0.82797480
97MP0001851_eye_inflammation0.81810271
98MP0005310_abnormal_salivary_gland0.80820330
99MP0001663_abnormal_digestive_system0.79984929
100MP0000003_abnormal_adipose_tissue0.79601049
101MP0001533_abnormal_skeleton_physiology0.79120588
102MP0004858_abnormal_nervous_system0.78877944
103MP0002075_abnormal_coat/hair_pigmentati0.78546760
104MP0010630_abnormal_cardiac_muscle0.77626259
105MP0000733_abnormal_muscle_development0.77374390
106MP0003646_muscle_fatigue0.75194430
107MP0009931_abnormal_skin_appearance0.74810598
108MP0008770_decreased_survivor_rate0.74283528
109MP0005058_abnormal_lysosome_morphology0.73905084
110MP0000350_abnormal_cell_proliferation0.72440515
111MP0001853_heart_inflammation0.71981630
112MP0005551_abnormal_eye_electrophysiolog0.71689889
113MP0003091_abnormal_cell_migration0.71566844
114MP0005501_abnormal_skin_physiology0.71285653
115MP0003950_abnormal_plasma_membrane0.70783704
116MP0001986_abnormal_taste_sensitivity0.70644187
117MP0001915_intracranial_hemorrhage0.70576168
118MP0001324_abnormal_eye_pigmentation0.70147605
119MP0003075_altered_response_to0.69914574
120MP0000249_abnormal_blood_vessel0.69580640
121MP0008874_decreased_physiological_sensi0.69485576
122MP0004233_abnormal_muscle_weight0.69375213
123MP0001849_ear_inflammation0.69278223
124MP0009115_abnormal_fat_cell0.67439330
125MP0010234_abnormal_vibrissa_follicle0.64674634
126MP0004264_abnormal_extraembryonic_tissu0.61675288
127MP0002971_abnormal_brown_adipose0.61235902
128MP0000747_muscle_weakness0.59936471
129MP0008004_abnormal_stomach_pH0.59878969
130MP0008569_lethality_at_weaning0.56000038

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)6.59465550
2Verrucae (HP:0200043)6.35210809
3Papilloma (HP:0012740)6.35210809
4Cellulitis (HP:0100658)6.07153101
5Eczematoid dermatitis (HP:0000976)5.65703138
6Thyroiditis (HP:0100646)5.06976691
7B lymphocytopenia (HP:0010976)4.99558745
8Abnormality of B cell number (HP:0010975)4.99558745
9Panhypogammaglobulinemia (HP:0003139)4.67359517
10Recurrent viral infections (HP:0004429)4.54686416
11Severe combined immunodeficiency (HP:0004430)4.23465134
12T lymphocytopenia (HP:0005403)4.19054050
13Recurrent bronchitis (HP:0002837)4.10429821
14Combined immunodeficiency (HP:0005387)4.04189239
15Abnormality of T cell number (HP:0011839)3.88472221
16Meningitis (HP:0001287)3.76648678
17Hypoplasia of the thymus (HP:0000778)3.69945466
18Colitis (HP:0002583)3.69254269
19Abnormality of the fingertips (HP:0001211)3.63299672
20Recurrent fungal infections (HP:0002841)3.63249530
21Inflammation of the large intestine (HP:0002037)3.62036164
22Gastrointestinal inflammation (HP:0004386)3.61772454
23Abnormality of macrophages (HP:0004311)3.59431450
24Chronic otitis media (HP:0000389)3.58998370
25Osteomyelitis (HP:0002754)3.56870073
26Myositis (HP:0100614)3.43135601
27Mediastinal lymphadenopathy (HP:0100721)3.38662105
28Abnormality of the intervertebral disk (HP:0005108)3.38536363
29Vertebral arch anomaly (HP:0008438)3.26744317
30Sepsis (HP:0100806)3.25334010
31Recurrent gram-negative bacterial infections (HP:0005420)3.24918099
32Gastrointestinal infarctions (HP:0005244)3.21448658
33Spontaneous hematomas (HP:0007420)3.13086346
34Small epiphyses (HP:0010585)3.07992035
35Gingivitis (HP:0000230)3.01622512
36Obstructive lung disease (HP:0006536)3.00050296
37Chronic obstructive pulmonary disease (HP:0006510)3.00050296
38Orchitis (HP:0100796)2.96111043
39Bony spicule pigmentary retinopathy (HP:0007737)2.95322129
40Chronic sinusitis (HP:0011109)2.94823429
41Hyperacusis (HP:0010780)2.86212056
42Elevated erythrocyte sedimentation rate (HP:0003565)2.85219944
43Abnormality of T cells (HP:0002843)2.85151128
44Eosinophilia (HP:0001880)2.78592021
45Abnormal delayed hypersensitivity skin test (HP:0002963)2.74797590
46IgM deficiency (HP:0002850)2.74360303
47Absent rod-and cone-mediated responses on ERG (HP:0007688)2.70999460
48Obstructive sleep apnea (HP:0002870)2.69754529
49Autoimmune thrombocytopenia (HP:0001973)2.66367607
50Retrobulbar optic neuritis (HP:0100654)2.65002939
51Optic neuritis (HP:0100653)2.65002939
52Ulnar bowing (HP:0003031)2.63156505
53Fatigue (HP:0012378)2.58022161
54Long eyelashes (HP:0000527)2.57999176
55Abnormality of the nasal mucosa (HP:0000433)2.57966498
56Nasal polyposis (HP:0100582)2.53815995
57Recurrent sinusitis (HP:0011108)2.52694909
58Encephalitis (HP:0002383)2.52579474
59Viral hepatitis (HP:0006562)2.47506965
60Recurrent otitis media (HP:0000403)2.45267122
61Lymphopenia (HP:0001888)2.39975861
62Abnormality of eosinophils (HP:0001879)2.39030682
63Slow saccadic eye movements (HP:0000514)2.37064653
64Difficulty running (HP:0009046)2.35157045
65Stomatitis (HP:0010280)2.34914084
66Abnormality of cells of the lymphoid lineage (HP:0012140)2.33379784
67Urticaria (HP:0001025)2.32332605
68Cutis marmorata (HP:0000965)2.31924335
69Pustule (HP:0200039)2.30028726
70Hypoproteinemia (HP:0003075)2.29263559
71Centrally nucleated skeletal muscle fibers (HP:0003687)2.29048152
72IgG deficiency (HP:0004315)2.28797866
73Skin rash (HP:0000988)2.26353459
74Granulocytopenia (HP:0001913)2.24310269
75Bronchitis (HP:0012387)2.24118100
76Increased IgE level (HP:0003212)2.23769951
77Hypochromic anemia (HP:0001931)2.23701025
78Hypoplasia of the capital femoral epiphysis (HP:0003090)2.22142630
79Interstitial pulmonary disease (HP:0006530)2.21087564
80Hematochezia (HP:0002573)2.20145729
81Congenital stationary night blindness (HP:0007642)2.18268463
82Exercise-induced myalgia (HP:0003738)2.17980462
83Mitral stenosis (HP:0001718)2.16906123
84Poikilocytosis (HP:0004447)2.16465516
85Restrictive lung disease (HP:0002091)2.13528247
86Polycythemia (HP:0001901)2.12411965
87Keratoconjunctivitis sicca (HP:0001097)2.11419609
88Chronic mucocutaneous candidiasis (HP:0002728)2.11269764
89Recurrent cutaneous fungal infections (HP:0011370)2.11269764
90Recurrent pneumonia (HP:0006532)2.09584483
91Flattened epiphyses (HP:0003071)2.09482337
92Papilledema (HP:0001085)2.08497932
93Abnormal rod and cone electroretinograms (HP:0008323)2.07371875
94Gastrointestinal stroma tumor (HP:0100723)2.05215009
95Epistaxis (HP:0000421)2.05193210
96Acute lymphatic leukemia (HP:0006721)2.04764202
97Cutaneous melanoma (HP:0012056)2.03188192
98Leukocytosis (HP:0001974)2.00930240
99Pulmonary infiltrates (HP:0002113)2.00610251
100Subacute progressive viral hepatitis (HP:0006572)1.99847894
101Pigmentary retinal degeneration (HP:0001146)1.94459363
102Ocular albinism (HP:0001107)1.93630443
103Skin ulcer (HP:0200042)1.93554464
104Prolonged bleeding time (HP:0003010)1.92651218
105Increased variability in muscle fiber diameter (HP:0003557)1.92433714
106Broad face (HP:0000283)1.90872207
107Macroorchidism (HP:0000053)1.89600317
108Abnormality of skeletal muscle fiber size (HP:0012084)1.88938980
109Hypochromic microcytic anemia (HP:0004840)1.88494949
110Limited elbow extension (HP:0001377)1.86119660
111Recurrent abscess formation (HP:0002722)1.85823591
112Metaphyseal cupping (HP:0003021)1.85541536
113Hemoptysis (HP:0002105)1.85224767
114Pulmonary embolism (HP:0002204)1.85098412
115Arterial thrombosis (HP:0004420)1.84035433
116Insomnia (HP:0100785)1.83840372
117Recurrent lower respiratory tract infections (HP:0002783)1.83839702
118Segmental peripheral demyelination/remyelination (HP:0003481)1.82787847
119Malnutrition (HP:0004395)1.81918463
120Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.81260232
121Increased density of long bones (HP:0006392)1.80992032
122Keratoconjunctivitis (HP:0001096)1.80876152
123Increased connective tissue (HP:0009025)1.80266764
124Germ cell neoplasia (HP:0100728)1.80090549
125Toxemia of pregnancy (HP:0100603)1.78981881
126Abnormality of the peritoneum (HP:0002585)1.77436616
127Gingival bleeding (HP:0000225)1.77071782
128Hyporeflexia of lower limbs (HP:0002600)1.77041828
129Abnormality of T cell physiology (HP:0011840)1.75932941
130Basal cell carcinoma (HP:0002671)1.75493470
131Aplasia/Hypoplasia of the thymus (HP:0010515)1.74252895
132Thrombocytosis (HP:0001894)1.73890682
133Emphysema (HP:0002097)1.73311771
134Polygenic inheritance (HP:0010982)1.73183998
135Asymmetric septal hypertrophy (HP:0001670)1.72449983
136Microcytic anemia (HP:0001935)1.71690615
137Distal lower limb muscle weakness (HP:0009053)1.69887311
138Increased cerebral lipofuscin (HP:0011813)1.69672626
139Purpura (HP:0000979)1.69579401
140Ankle clonus (HP:0011448)1.68437209
141Cerebral aneurysm (HP:0004944)1.68243429
142Chest pain (HP:0100749)1.67365034
143Muscle fiber splitting (HP:0003555)1.67178039
144Volvulus (HP:0002580)1.65945039
145Recurrent bacterial skin infections (HP:0005406)1.65404686
146Albinism (HP:0001022)1.65307852
147Lymphoma (HP:0002665)1.63391130
148Recurrent skin infections (HP:0001581)1.61085645
149Abnormality of the thymus (HP:0000777)1.60158399
150Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.60078215
151Absent epiphyses (HP:0010577)1.60078215
152Vasculitis (HP:0002633)1.58671223

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K107.72168537
2PRPF4B4.13400821
3EEF2K3.99733944
4MAP4K13.16992984
5TRIB32.95015557
6ERN12.86080830
7GRK62.66225844
8PKN22.49340229
9CDK122.27864401
10SMG12.11194001
11STK102.09076928
12STK41.88438881
13SIK21.86441805
14IRAK41.78670743
15NEK21.58012664
16TYK21.53926116
17CLK11.50109631
18CDK41.49184263
19BTK1.46820136
20TLK11.44573536
21SYK1.38698415
22MAP3K31.36135349
23CAMK1D1.34439095
24LRRK21.33957320
25KSR21.33558489
26MAP3K111.31758591
27ZAP701.31120505
28MAP3K71.30794300
29CSF1R1.24861905
30MAP3K11.20065489
31SIK31.14627254
32CDK91.13337640
33SIK11.13021287
34MARK31.12840585
35JAK31.10253509
36MAPK121.10107303
37MAPK111.09904969
38JAK11.09807980
39ITK1.06197877
40PIM11.05432887
41CAMK1G1.05368073
42HCK1.04840289
43RPS6KB21.02941342
44EPHB11.01898323
45MAP3K141.01826184
46HIPK21.01662239
47BLK1.01530401
48MST1R0.99527027
49BMX0.99516854
50TGFBR20.99308915
51PDPK10.98043514
52CAMKK10.97843992
53MARK20.97348032
54CDC42BPA0.96878317
55FGFR30.94676445
56FES0.93903807
57TBK10.93687370
58FGFR40.92670880
59PTK60.90831311
60LCK0.86618275
61TAOK20.86343741
62FGFR20.85558368
63CDK60.85123951
64ICK0.83324940
65DYRK1B0.80204840
66CSK0.80178468
67IRAK20.78784644
68SCYL20.77704331
69TXK0.77148524
70FGR0.76477600
71RPS6KL10.74985928
72RPS6KC10.74985928
73MAPK40.73734512
74TESK20.73444890
75NLK0.72701296
76MAP3K20.72661621
77TNK20.72501197
78RIPK10.71697143
79MAP2K20.70726444
80IKBKE0.69955564
81RIPK40.69886124
82MELK0.69465882
83PRKD10.68986556
84MAP3K60.68425233
85MAP2K30.68406619
86LYN0.66681866
87TRPM70.66630388
88MAP3K80.66151018
89RPS6KA20.65483197
90MAPKAPK30.64713148
91TTN0.63646801
92BRD40.63106539
93PRKD20.62969957
94MAPK70.62308199
95PRKD30.60813506
96FLT30.59373840
97JAK20.59197242
98PRKCH0.57890432
99RPS6KA60.57104071
100WNK10.56466095
101PRKAA20.54950629
102STK110.54785494
103SGK30.54567956
104YES10.51108205
105SGK20.48894520
106RPS6KA40.47987254
107CDC70.46800846
108CAMK40.46599400
109IRAK10.45410415
110PDK10.44644325
111MTOR0.43768675
112UHMK10.43215139
113BMPR20.42534077
114PIK3CG0.42438919
115DMPK0.41979903
116KDR0.40078481
117MAPKAPK20.40008081
118PKN10.39579896
119IKBKB0.38262911
120TYRO30.37145707
121TEC0.37073821
122RPS6KA50.36914905
123RET0.36220441
124PRKAA10.35409938
125KIT0.35061871
126PDGFRB0.34774369
127CSNK1D0.33885059
128PRKCQ0.33646685
129TAOK10.33583519
130FYN0.32736451
131CHUK0.30108106
132DYRK30.30059555
133MAP3K130.27264058

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.86275864
2B cell receptor signaling pathway_Homo sapiens_hsa046623.68162409
3Systemic lupus erythematosus_Homo sapiens_hsa053222.56233003
4Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.46037431
5Chronic myeloid leukemia_Homo sapiens_hsa052202.10379465
6Osteoclast differentiation_Homo sapiens_hsa043801.98635654
7Non-homologous end-joining_Homo sapiens_hsa034501.98527947
8Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.90580449
9Phototransduction_Homo sapiens_hsa047441.86269017
10Graft-versus-host disease_Homo sapiens_hsa053321.82112658
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.80785957
12Allograft rejection_Homo sapiens_hsa053301.77562014
13Autoimmune thyroid disease_Homo sapiens_hsa053201.77468047
14Non-small cell lung cancer_Homo sapiens_hsa052231.76980164
15Staphylococcus aureus infection_Homo sapiens_hsa051501.72237379
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.69664721
17T cell receptor signaling pathway_Homo sapiens_hsa046601.61626738
18Measles_Homo sapiens_hsa051621.58427008
19Other glycan degradation_Homo sapiens_hsa005111.53232419
20Pancreatic cancer_Homo sapiens_hsa052121.51984671
21Viral carcinogenesis_Homo sapiens_hsa052031.51649142
22Acute myeloid leukemia_Homo sapiens_hsa052211.46813496
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.44958840
24Transcriptional misregulation in cancer_Homo sapiens_hsa052021.44515393
25Leishmaniasis_Homo sapiens_hsa051401.41625710
26Intestinal immune network for IgA production_Homo sapiens_hsa046721.40717567
27Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.38244876
28Lysine degradation_Homo sapiens_hsa003101.36285953
29Chemokine signaling pathway_Homo sapiens_hsa040621.33897256
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.33427894
31Phosphatidylinositol signaling system_Homo sapiens_hsa040701.29508018
32Platelet activation_Homo sapiens_hsa046111.23872310
33Alcoholism_Homo sapiens_hsa050341.23506596
34Small cell lung cancer_Homo sapiens_hsa052221.23485029
35Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.22335404
36Base excision repair_Homo sapiens_hsa034101.21327854
37Insulin resistance_Homo sapiens_hsa049311.19077386
38Hematopoietic cell lineage_Homo sapiens_hsa046401.16407297
39VEGF signaling pathway_Homo sapiens_hsa043701.16062107
40Antigen processing and presentation_Homo sapiens_hsa046121.15141629
41Type I diabetes mellitus_Homo sapiens_hsa049401.13458520
42Toxoplasmosis_Homo sapiens_hsa051451.13235753
43Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.12235846
44Olfactory transduction_Homo sapiens_hsa047401.08568048
45Jak-STAT signaling pathway_Homo sapiens_hsa046301.07539224
46Hepatitis B_Homo sapiens_hsa051611.07493494
47Apoptosis_Homo sapiens_hsa042101.06766511
48GnRH signaling pathway_Homo sapiens_hsa049121.05919674
49HTLV-I infection_Homo sapiens_hsa051661.05724102
50Inositol phosphate metabolism_Homo sapiens_hsa005621.05470930
51mTOR signaling pathway_Homo sapiens_hsa041501.04802707
52Herpes simplex infection_Homo sapiens_hsa051681.02782789
53Glioma_Homo sapiens_hsa052141.02609087
54Neurotrophin signaling pathway_Homo sapiens_hsa047221.00369193
55Viral myocarditis_Homo sapiens_hsa054160.97816405
56Carbohydrate digestion and absorption_Homo sapiens_hsa049730.96892563
57Asthma_Homo sapiens_hsa053100.96541193
58Long-term potentiation_Homo sapiens_hsa047200.96277469
59Pentose phosphate pathway_Homo sapiens_hsa000300.95783154
60Adipocytokine signaling pathway_Homo sapiens_hsa049200.95736509
61ErbB signaling pathway_Homo sapiens_hsa040120.90838817
62Sphingolipid signaling pathway_Homo sapiens_hsa040710.90408783
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.86802011
64FoxO signaling pathway_Homo sapiens_hsa040680.86678579
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86037375
66Phospholipase D signaling pathway_Homo sapiens_hsa040720.84611697
67MicroRNAs in cancer_Homo sapiens_hsa052060.84230128
68Renal cell carcinoma_Homo sapiens_hsa052110.83696844
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82948567
70AMPK signaling pathway_Homo sapiens_hsa041520.82921342
71Shigellosis_Homo sapiens_hsa051310.82843847
72Colorectal cancer_Homo sapiens_hsa052100.82647282
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81742606
74DNA replication_Homo sapiens_hsa030300.80234082
75Toll-like receptor signaling pathway_Homo sapiens_hsa046200.78203693
76Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.78097418
77Endocytosis_Homo sapiens_hsa041440.75897686
78Tuberculosis_Homo sapiens_hsa051520.75543187
79Notch signaling pathway_Homo sapiens_hsa043300.74375315
80Estrogen signaling pathway_Homo sapiens_hsa049150.74135442
81Thyroid cancer_Homo sapiens_hsa052160.73941952
82Phagosome_Homo sapiens_hsa041450.73898811
83Influenza A_Homo sapiens_hsa051640.73679149
84Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70838404
85Dorso-ventral axis formation_Homo sapiens_hsa043200.69811501
86Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69508585
87Type II diabetes mellitus_Homo sapiens_hsa049300.67721669
88Malaria_Homo sapiens_hsa051440.66960143
89HIF-1 signaling pathway_Homo sapiens_hsa040660.66679637
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65325658
91Glycerolipid metabolism_Homo sapiens_hsa005610.65304979
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.64801069
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63600458
94Cell cycle_Homo sapiens_hsa041100.63302360
95Choline metabolism in cancer_Homo sapiens_hsa052310.62490505
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61334158
97ABC transporters_Homo sapiens_hsa020100.61122914
98Insulin signaling pathway_Homo sapiens_hsa049100.59636262
99Pertussis_Homo sapiens_hsa051330.58354992
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.57277457
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57059547
102Prostate cancer_Homo sapiens_hsa052150.55381281
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54782941
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54720235
105Epstein-Barr virus infection_Homo sapiens_hsa051690.54469465
106p53 signaling pathway_Homo sapiens_hsa041150.53888207
107Fatty acid biosynthesis_Homo sapiens_hsa000610.53381817
108cGMP-PKG signaling pathway_Homo sapiens_hsa040220.52802876
109Rap1 signaling pathway_Homo sapiens_hsa040150.51982134
110Hepatitis C_Homo sapiens_hsa051600.51643254
111Proteoglycans in cancer_Homo sapiens_hsa052050.51159675
112MAPK signaling pathway_Homo sapiens_hsa040100.50383763
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50217130
114Amoebiasis_Homo sapiens_hsa051460.49959272
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49929842
116Prolactin signaling pathway_Homo sapiens_hsa049170.49339804
117Endometrial cancer_Homo sapiens_hsa052130.48926623
118Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47986441
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46450393
120Pathways in cancer_Homo sapiens_hsa052000.45391772
121TNF signaling pathway_Homo sapiens_hsa046680.45103338
122Mismatch repair_Homo sapiens_hsa034300.42932198
123NOD-like receptor signaling pathway_Homo sapiens_hsa046210.39761252
124Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39566247
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38810054

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