

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 7.02151323 |
| 2 | rRNA modification (GO:0000154) | 5.60133733 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.39851104 |
| 4 | protein neddylation (GO:0045116) | 5.39644688 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.19880142 |
| 6 | rRNA methylation (GO:0031167) | 5.18429574 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.17977056 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 5.17977056 |
| 9 | maturation of 5.8S rRNA (GO:0000460) | 4.75138025 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.53234071 |
| 11 | DNA deamination (GO:0045006) | 4.48447187 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 4.33839624 |
| 13 | termination of RNA polymerase III transcription (GO:0006386) | 4.33567195 |
| 14 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.33567195 |
| 15 | GTP biosynthetic process (GO:0006183) | 4.06870721 |
| 16 | pseudouridine synthesis (GO:0001522) | 3.95929191 |
| 17 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.94463625 |
| 18 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.94463625 |
| 19 | isotype switching (GO:0045190) | 3.94463625 |
| 20 | cullin deneddylation (GO:0010388) | 3.93208757 |
| 21 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.91153405 |
| 22 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.91153405 |
| 23 | respiratory chain complex IV assembly (GO:0008535) | 3.77982855 |
| 24 | protein complex biogenesis (GO:0070271) | 3.72040978 |
| 25 | protein deneddylation (GO:0000338) | 3.71571167 |
| 26 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.71025546 |
| 27 | DNA damage response, detection of DNA damage (GO:0042769) | 3.61896463 |
| 28 | respiratory electron transport chain (GO:0022904) | 3.61710935 |
| 29 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.59227266 |
| 30 | electron transport chain (GO:0022900) | 3.58355464 |
| 31 | protein targeting to mitochondrion (GO:0006626) | 3.55911735 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.55015056 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.55015056 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.55015056 |
| 35 | cytochrome complex assembly (GO:0017004) | 3.52432838 |
| 36 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.51200071 |
| 37 | UTP biosynthetic process (GO:0006228) | 3.51018430 |
| 38 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.50706748 |
| 39 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.50156724 |
| 40 | ribosomal large subunit biogenesis (GO:0042273) | 3.49684280 |
| 41 | CTP biosynthetic process (GO:0006241) | 3.47310032 |
| 42 | CTP metabolic process (GO:0046036) | 3.47310032 |
| 43 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.47265617 |
| 44 | regulation of immunoglobulin secretion (GO:0051023) | 3.46124688 |
| 45 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.37309360 |
| 46 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.37309360 |
| 47 | protein localization to mitochondrion (GO:0070585) | 3.35846091 |
| 48 | ATP biosynthetic process (GO:0006754) | 3.33619866 |
| 49 | establishment of protein localization to mitochondrion (GO:0072655) | 3.31399878 |
| 50 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.26118150 |
| 51 | regulation of mitochondrial translation (GO:0070129) | 3.23727273 |
| 52 | DNA ligation (GO:0006266) | 3.21390718 |
| 53 | tRNA processing (GO:0008033) | 3.21145654 |
| 54 | organelle disassembly (GO:1903008) | 3.20392750 |
| 55 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.19982376 |
| 56 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.18644877 |
| 57 | rRNA processing (GO:0006364) | 3.17650750 |
| 58 | response to pheromone (GO:0019236) | 3.14337025 |
| 59 | UTP metabolic process (GO:0046051) | 3.14304541 |
| 60 | mitochondrial RNA metabolic process (GO:0000959) | 3.13260868 |
| 61 | rRNA metabolic process (GO:0016072) | 3.10411316 |
| 62 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.10281193 |
| 63 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.07150114 |
| 64 | histone mRNA metabolic process (GO:0008334) | 3.03676915 |
| 65 | spliceosomal snRNP assembly (GO:0000387) | 3.03310021 |
| 66 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.02902339 |
| 67 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.00565837 |
| 68 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.00486913 |
| 69 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.99550616 |
| 70 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.99550616 |
| 71 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.99550616 |
| 72 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.97659569 |
| 73 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.97642078 |
| 74 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.97642078 |
| 75 | spliceosomal complex assembly (GO:0000245) | 2.97565558 |
| 76 | somatic diversification of immunoglobulins (GO:0016445) | 2.97527373 |
| 77 | chromatin remodeling at centromere (GO:0031055) | 2.97492155 |
| 78 | intracellular protein transmembrane import (GO:0044743) | 2.96715262 |
| 79 | DNA double-strand break processing (GO:0000729) | 2.95688561 |
| 80 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.86328957 |
| 81 | transcription from mitochondrial promoter (GO:0006390) | 2.86121605 |
| 82 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.85427504 |
| 83 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.85427504 |
| 84 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.85372919 |
| 85 | protein-cofactor linkage (GO:0018065) | 2.83283325 |
| 86 | hydrogen ion transmembrane transport (GO:1902600) | 2.81619081 |
| 87 | tRNA metabolic process (GO:0006399) | 2.81420612 |
| 88 | aldehyde catabolic process (GO:0046185) | 2.80694437 |
| 89 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.78370847 |
| 90 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.78352386 |
| 91 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.77873251 |
| 92 | CENP-A containing nucleosome assembly (GO:0034080) | 2.76917421 |
| 93 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.75242458 |
| 94 | ncRNA processing (GO:0034470) | 2.74856595 |
| 95 | ncRNA metabolic process (GO:0034660) | 2.74754608 |
| 96 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.73488934 |
| 97 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.71435396 |
| 98 | somatic diversification of immune receptors (GO:0002200) | 2.70311671 |
| 99 | cellular component biogenesis (GO:0044085) | 2.70285961 |
| 100 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.70039882 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.92668984 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.46002900 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82780174 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.27228784 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12168797 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.98591748 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.89535847 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.74851140 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.72398143 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.68270325 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.67694937 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.66878971 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.56862775 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.53853454 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.47787729 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.46999649 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22371638 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.17224131 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.15430007 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.13230989 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.10357777 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.08143723 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.01139103 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97222702 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.97128249 |
| 26 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.92826054 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.88408803 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.86830280 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.85618295 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.82233552 |
| 31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.78095150 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.76379252 |
| 33 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.76137604 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.70478489 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.64121847 |
| 36 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.61891540 |
| 37 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.55856417 |
| 38 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.54846614 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.54772619 |
| 40 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.51879763 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50921702 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.50602955 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.46761754 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.45291995 |
| 45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.42997099 |
| 46 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.40942191 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.38871527 |
| 48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38447182 |
| 49 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.34973872 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.33466083 |
| 51 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.33372215 |
| 52 | P300_19829295_ChIP-Seq_ESCs_Human | 1.27781812 |
| 53 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.27767937 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.26913018 |
| 55 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26290151 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26290151 |
| 57 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23281640 |
| 58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.23065112 |
| 59 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.22906001 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.22102958 |
| 61 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20952140 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18953887 |
| 63 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.15241463 |
| 64 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13914486 |
| 65 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.12917917 |
| 66 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.12509323 |
| 67 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.12305978 |
| 68 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11865534 |
| 69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.11751692 |
| 70 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.10451436 |
| 71 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08249975 |
| 72 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.07882508 |
| 73 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.07078760 |
| 74 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.06877126 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.04398605 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04318073 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04318073 |
| 78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03340338 |
| 79 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03340338 |
| 80 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03114979 |
| 81 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.02631263 |
| 82 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.02127589 |
| 83 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02058815 |
| 84 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96901378 |
| 85 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94087338 |
| 86 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.93268287 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93179087 |
| 88 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.93058915 |
| 89 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.90670017 |
| 90 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.89059265 |
| 91 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.88974095 |
| 92 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.87848310 |
| 93 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87459690 |
| 94 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.87159184 |
| 95 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.86463261 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.86142927 |
| 97 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85018916 |
| 98 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.83959193 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.83693041 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.81543950 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 4.21006768 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.25347230 |
| 3 | MP0001986_abnormal_taste_sensitivity | 2.97304478 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 2.45036413 |
| 5 | MP0001968_abnormal_touch/_nociception | 2.41077088 |
| 6 | MP0002736_abnormal_nociception_after | 2.30949015 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.21530700 |
| 8 | MP0003195_calcinosis | 2.17584265 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.11055635 |
| 10 | MP0003880_abnormal_central_pattern | 2.00285934 |
| 11 | MP0008872_abnormal_physiological_respon | 1.94169690 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 1.89289995 |
| 13 | MP0003693_abnormal_embryo_hatching | 1.85058873 |
| 14 | MP0008058_abnormal_DNA_repair | 1.84311600 |
| 15 | MP0008007_abnormal_cellular_replicative | 1.82878509 |
| 16 | MP0005671_abnormal_response_to | 1.81260608 |
| 17 | MP0003787_abnormal_imprinting | 1.78797138 |
| 18 | MP0006036_abnormal_mitochondrial_physio | 1.77316521 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.72461111 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.71113523 |
| 21 | MP0008057_abnormal_DNA_replication | 1.70357970 |
| 22 | MP0000516_abnormal_urinary_system | 1.66238908 |
| 23 | MP0005367_renal/urinary_system_phenotyp | 1.66238908 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.66181461 |
| 25 | MP0002102_abnormal_ear_morphology | 1.63467573 |
| 26 | MP0004957_abnormal_blastocyst_morpholog | 1.63462918 |
| 27 | MP0001529_abnormal_vocalization | 1.60357396 |
| 28 | MP0005423_abnormal_somatic_nervous | 1.57732992 |
| 29 | MP0004147_increased_porphyrin_level | 1.57496707 |
| 30 | MP0004885_abnormal_endolymph | 1.57003061 |
| 31 | MP0003786_premature_aging | 1.55072460 |
| 32 | MP0003718_maternal_effect | 1.54471409 |
| 33 | MP0005083_abnormal_biliary_tract | 1.54287956 |
| 34 | MP0010094_abnormal_chromosome_stability | 1.53909395 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.47736427 |
| 36 | MP0000631_abnormal_neuroendocrine_gland | 1.46201131 |
| 37 | MP0001501_abnormal_sleep_pattern | 1.44879375 |
| 38 | MP0002272_abnormal_nervous_system | 1.44870570 |
| 39 | MP0005253_abnormal_eye_physiology | 1.42628537 |
| 40 | MP0006035_abnormal_mitochondrial_morpho | 1.35508810 |
| 41 | MP0003045_fibrosis | 1.35285925 |
| 42 | MP0009046_muscle_twitch | 1.34575514 |
| 43 | MP0005410_abnormal_fertilization | 1.34038305 |
| 44 | MP0002751_abnormal_autonomic_nervous | 1.32917291 |
| 45 | MP0002163_abnormal_gland_morphology | 1.32912184 |
| 46 | MP0003122_maternal_imprinting | 1.31328234 |
| 47 | MP0003646_muscle_fatigue | 1.26742901 |
| 48 | MP0003567_abnormal_fetal_cardiomyocyte | 1.25886122 |
| 49 | MP0004142_abnormal_muscle_tone | 1.19189795 |
| 50 | MP0000049_abnormal_middle_ear | 1.18578047 |
| 51 | MP0009785_altered_susceptibility_to | 1.14485176 |
| 52 | MP0002638_abnormal_pupillary_reflex | 1.12167201 |
| 53 | MP0001764_abnormal_homeostasis | 1.08993143 |
| 54 | MP0008932_abnormal_embryonic_tissue | 1.07931103 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 1.07024318 |
| 56 | MP0003011_delayed_dark_adaptation | 1.04900172 |
| 57 | MP0003121_genomic_imprinting | 1.04737870 |
| 58 | MP0001835_abnormal_antigen_presentation | 1.04657594 |
| 59 | MP0009745_abnormal_behavioral_response | 1.03814132 |
| 60 | MP0002234_abnormal_pharynx_morphology | 1.03780444 |
| 61 | MP0004215_abnormal_myocardial_fiber | 1.02698739 |
| 62 | MP0002210_abnormal_sex_determination | 0.99937736 |
| 63 | MP0002160_abnormal_reproductive_system | 0.98690422 |
| 64 | MP0002938_white_spotting | 0.98417455 |
| 65 | MP0008789_abnormal_olfactory_epithelium | 0.96928433 |
| 66 | MP0001905_abnormal_dopamine_level | 0.95743937 |
| 67 | MP0005187_abnormal_penis_morphology | 0.94970625 |
| 68 | MP0003119_abnormal_digestive_system | 0.93471816 |
| 69 | MP0005389_reproductive_system_phenotype | 0.90538672 |
| 70 | MP0000653_abnormal_sex_gland | 0.87904012 |
| 71 | MP0003137_abnormal_impulse_conducting | 0.87418145 |
| 72 | MP0001293_anophthalmia | 0.86167601 |
| 73 | MP0001929_abnormal_gametogenesis | 0.84839111 |
| 74 | MP0001119_abnormal_female_reproductive | 0.82962617 |
| 75 | MP0002733_abnormal_thermal_nociception | 0.82458226 |
| 76 | MP0002735_abnormal_chemical_nociception | 0.81636082 |
| 77 | MP0001970_abnormal_pain_threshold | 0.80157344 |
| 78 | MP0001145_abnormal_male_reproductive | 0.79414535 |
| 79 | MP0004133_heterotaxia | 0.76673177 |
| 80 | MP0001485_abnormal_pinna_reflex | 0.76513827 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.72724122 |
| 82 | MP0001486_abnormal_startle_reflex | 0.72015086 |
| 83 | MP0005395_other_phenotype | 0.71236907 |
| 84 | MP0001879_abnormal_lymphatic_vessel | 0.70569454 |
| 85 | MP0002752_abnormal_somatic_nervous | 0.70012148 |
| 86 | MP0000685_abnormal_immune_system | 0.69411040 |
| 87 | MP0003186_abnormal_redox_activity | 0.68470086 |
| 88 | MP0002572_abnormal_emotion/affect_behav | 0.68258170 |
| 89 | MP0003111_abnormal_nucleus_morphology | 0.67652868 |
| 90 | MP0005195_abnormal_posterior_eye | 0.67451036 |
| 91 | MP0002067_abnormal_sensory_capabilities | 0.66956487 |
| 92 | MP0000372_irregular_coat_pigmentation | 0.66271212 |
| 93 | MP0001919_abnormal_reproductive_system | 0.65940683 |
| 94 | MP0010386_abnormal_urinary_bladder | 0.65301948 |
| 95 | MP0001984_abnormal_olfaction | 0.64443352 |
| 96 | MP0003938_abnormal_ear_development | 0.63746244 |
| 97 | MP0003698_abnormal_male_reproductive | 0.63536036 |
| 98 | MP0002229_neurodegeneration | 0.62968823 |
| 99 | MP0005391_vision/eye_phenotype | 0.62492913 |
| 100 | MP0009379_abnormal_foot_pigmentation | 0.61595578 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 5.13126316 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.81289846 |
| 3 | 3-Methylglutaconic aciduria (HP:0003535) | 4.75874714 |
| 4 | Acute encephalopathy (HP:0006846) | 4.34977593 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.11558109 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.97688284 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.96963506 |
| 8 | Increased CSF lactate (HP:0002490) | 3.67777445 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.59477459 |
| 10 | Pancreatic cysts (HP:0001737) | 3.53755533 |
| 11 | Molar tooth sign on MRI (HP:0002419) | 3.53495706 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.53495706 |
| 13 | Cerebral edema (HP:0002181) | 3.32552058 |
| 14 | Hepatic necrosis (HP:0002605) | 3.28008070 |
| 15 | Pancreatic fibrosis (HP:0100732) | 3.11371969 |
| 16 | IgG deficiency (HP:0004315) | 3.07717220 |
| 17 | Hyperglycinemia (HP:0002154) | 2.82805903 |
| 18 | Abnormality of the pons (HP:0007361) | 2.75637013 |
| 19 | Increased IgM level (HP:0003496) | 2.73184791 |
| 20 | Median cleft lip (HP:0000161) | 2.69622910 |
| 21 | Multiple enchondromatosis (HP:0005701) | 2.65835439 |
| 22 | True hermaphroditism (HP:0010459) | 2.65016782 |
| 23 | Increased serum lactate (HP:0002151) | 2.60657052 |
| 24 | Medial flaring of the eyebrow (HP:0010747) | 2.59243115 |
| 25 | Optic disc pallor (HP:0000543) | 2.57138379 |
| 26 | Nephronophthisis (HP:0000090) | 2.54065971 |
| 27 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.52966125 |
| 28 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.52966125 |
| 29 | Abnormality of the anterior horn cell (HP:0006802) | 2.51214242 |
| 30 | Degeneration of anterior horn cells (HP:0002398) | 2.51214242 |
| 31 | Hyperglycinuria (HP:0003108) | 2.47832782 |
| 32 | Methylmalonic acidemia (HP:0002912) | 2.36335559 |
| 33 | Respiratory failure (HP:0002878) | 2.35992390 |
| 34 | Cortical visual impairment (HP:0100704) | 2.33248803 |
| 35 | Abnormality of the renal cortex (HP:0011035) | 2.33147552 |
| 36 | Lactic acidosis (HP:0003128) | 2.32294707 |
| 37 | Congenital, generalized hypertrichosis (HP:0004540) | 2.31939677 |
| 38 | Lipid accumulation in hepatocytes (HP:0006561) | 2.26139864 |
| 39 | Polyuria (HP:0000103) | 2.25587857 |
| 40 | Abnormality of the renal medulla (HP:0100957) | 2.24562369 |
| 41 | Abnormality of the renal collecting system (HP:0004742) | 2.24202237 |
| 42 | Abnormal drinking behavior (HP:0030082) | 2.24093177 |
| 43 | Polydipsia (HP:0001959) | 2.24093177 |
| 44 | Increased hepatocellular lipid droplets (HP:0006565) | 2.23968250 |
| 45 | Lethargy (HP:0001254) | 2.23774406 |
| 46 | Parakeratosis (HP:0001036) | 2.23202082 |
| 47 | Hypochromic microcytic anemia (HP:0004840) | 2.21328906 |
| 48 | Stenosis of the external auditory canal (HP:0000402) | 2.17956705 |
| 49 | Hypoproteinemia (HP:0003075) | 2.15220457 |
| 50 | Leukodystrophy (HP:0002415) | 2.13125720 |
| 51 | Posterior subcapsular cataract (HP:0007787) | 2.12419965 |
| 52 | Meckel diverticulum (HP:0002245) | 2.12184673 |
| 53 | Exercise intolerance (HP:0003546) | 2.11160616 |
| 54 | Broad alveolar ridges (HP:0000187) | 2.10729634 |
| 55 | Abnormality of the ileum (HP:0001549) | 2.08195351 |
| 56 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.08022137 |
| 57 | Abnormality of glycine metabolism (HP:0010895) | 2.07235547 |
| 58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.07235547 |
| 59 | Duplicated collecting system (HP:0000081) | 2.06696916 |
| 60 | Abnormality of the labia minora (HP:0012880) | 2.06244479 |
| 61 | Generalized aminoaciduria (HP:0002909) | 2.05702021 |
| 62 | Microvesicular hepatic steatosis (HP:0001414) | 2.03514641 |
| 63 | Sclerocornea (HP:0000647) | 2.03171081 |
| 64 | Anencephaly (HP:0002323) | 2.02983138 |
| 65 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.01588991 |
| 66 | Abnormality of serum amino acid levels (HP:0003112) | 2.01099006 |
| 67 | Pendular nystagmus (HP:0012043) | 1.99267245 |
| 68 | Methylmalonic aciduria (HP:0012120) | 1.98207319 |
| 69 | Cystic liver disease (HP:0006706) | 1.97661823 |
| 70 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.94648124 |
| 71 | Preaxial hand polydactyly (HP:0001177) | 1.94550429 |
| 72 | Triphalangeal thumb (HP:0001199) | 1.92174213 |
| 73 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.89646004 |
| 74 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.87976266 |
| 75 | Absent thumb (HP:0009777) | 1.85060422 |
| 76 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.83014281 |
| 77 | CNS demyelination (HP:0007305) | 1.79487472 |
| 78 | Abnormality of methionine metabolism (HP:0010901) | 1.77924292 |
| 79 | Renal Fanconi syndrome (HP:0001994) | 1.77885470 |
| 80 | Ectopic kidney (HP:0000086) | 1.76364695 |
| 81 | Hypoplasia of the pons (HP:0012110) | 1.75522962 |
| 82 | Abnormal urine output (HP:0012590) | 1.75059702 |
| 83 | Cerebral hypomyelination (HP:0006808) | 1.74982522 |
| 84 | Large for gestational age (HP:0001520) | 1.74745417 |
| 85 | Opisthotonus (HP:0002179) | 1.74646611 |
| 86 | Failure to thrive in infancy (HP:0001531) | 1.74083513 |
| 87 | Absent septum pellucidum (HP:0001331) | 1.73431931 |
| 88 | Limb dystonia (HP:0002451) | 1.72811279 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.71559556 |
| 90 | Hyperalaninemia (HP:0003348) | 1.71559556 |
| 91 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.71559556 |
| 92 | Severe combined immunodeficiency (HP:0004430) | 1.70929899 |
| 93 | Congenital stationary night blindness (HP:0007642) | 1.70810519 |
| 94 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.70579553 |
| 95 | Dicarboxylic aciduria (HP:0003215) | 1.69710949 |
| 96 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.69710949 |
| 97 | Type 2 muscle fiber atrophy (HP:0003554) | 1.69396216 |
| 98 | Oral leukoplakia (HP:0002745) | 1.69181182 |
| 99 | Abnormality of T cell physiology (HP:0011840) | 1.68691587 |
| 100 | Reticulocytopenia (HP:0001896) | 1.68246914 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 3.28155324 |
| 2 | VRK2 | 3.13437430 |
| 3 | TSSK6 | 3.13102398 |
| 4 | MKNK1 | 2.95886025 |
| 5 | ZAK | 2.94137230 |
| 6 | WNK3 | 2.49294214 |
| 7 | VRK1 | 2.43462467 |
| 8 | TLK1 | 2.39096552 |
| 9 | TXK | 2.33372747 |
| 10 | NME2 | 2.30022757 |
| 11 | SRPK1 | 2.16810859 |
| 12 | OXSR1 | 2.14014895 |
| 13 | STK39 | 2.09265787 |
| 14 | EIF2AK3 | 2.06007185 |
| 15 | MKNK2 | 2.04664938 |
| 16 | MST4 | 2.00546219 |
| 17 | NEK1 | 1.97350072 |
| 18 | EIF2AK1 | 1.95884985 |
| 19 | BCR | 1.88916602 |
| 20 | PLK3 | 1.86622226 |
| 21 | TAF1 | 1.81796165 |
| 22 | MAP4K2 | 1.78232209 |
| 23 | BUB1 | 1.65652432 |
| 24 | ADRBK2 | 1.60391538 |
| 25 | TRIM28 | 1.55410797 |
| 26 | GRK1 | 1.54789866 |
| 27 | PASK | 1.40704884 |
| 28 | MAP2K7 | 1.32691887 |
| 29 | STK16 | 1.31568799 |
| 30 | EIF2AK2 | 1.30860181 |
| 31 | TIE1 | 1.30448083 |
| 32 | WNK4 | 1.29550913 |
| 33 | MAP3K4 | 1.29214614 |
| 34 | MAPK13 | 1.26487447 |
| 35 | FRK | 1.25749820 |
| 36 | CSNK1G3 | 1.18159542 |
| 37 | DYRK2 | 1.18103022 |
| 38 | BMPR1B | 1.14787271 |
| 39 | PLK2 | 1.11311482 |
| 40 | CSNK1A1L | 1.08281851 |
| 41 | WEE1 | 1.04491797 |
| 42 | RPS6KA5 | 1.02321669 |
| 43 | CSNK1G1 | 1.00135292 |
| 44 | PLK4 | 0.94354773 |
| 45 | CSNK1G2 | 0.87957028 |
| 46 | MAPKAPK5 | 0.87420177 |
| 47 | PDK2 | 0.85478198 |
| 48 | INSRR | 0.84899149 |
| 49 | ERBB3 | 0.84887452 |
| 50 | KDR | 0.84722159 |
| 51 | PIM2 | 0.84522638 |
| 52 | PLK1 | 0.79984962 |
| 53 | CDK19 | 0.77476208 |
| 54 | TAOK3 | 0.77321481 |
| 55 | IKBKB | 0.71978476 |
| 56 | CDC7 | 0.71089724 |
| 57 | PHKG2 | 0.69869252 |
| 58 | PHKG1 | 0.69869252 |
| 59 | NME1 | 0.67299566 |
| 60 | TNIK | 0.65413364 |
| 61 | MAP3K12 | 0.63935077 |
| 62 | ALK | 0.62564331 |
| 63 | PRKCG | 0.59378810 |
| 64 | ATR | 0.56770374 |
| 65 | MINK1 | 0.53516753 |
| 66 | CSNK2A1 | 0.51782080 |
| 67 | TNK2 | 0.51725369 |
| 68 | FGFR3 | 0.50596080 |
| 69 | AURKB | 0.49862914 |
| 70 | CSNK1E | 0.46550167 |
| 71 | TEC | 0.46399515 |
| 72 | PRKCQ | 0.46271674 |
| 73 | CSNK2A2 | 0.46114321 |
| 74 | CAMK2A | 0.45866694 |
| 75 | ABL2 | 0.45122187 |
| 76 | CAMKK2 | 0.44135706 |
| 77 | DAPK3 | 0.41410125 |
| 78 | DYRK1A | 0.40538971 |
| 79 | PIM1 | 0.38960145 |
| 80 | PINK1 | 0.37737042 |
| 81 | IKBKE | 0.37579135 |
| 82 | CSNK1A1 | 0.36600219 |
| 83 | ADRBK1 | 0.36560344 |
| 84 | GRK5 | 0.36308942 |
| 85 | CHUK | 0.35386627 |
| 86 | PRKACA | 0.34936818 |
| 87 | ATM | 0.33498803 |
| 88 | CSNK1D | 0.33445884 |
| 89 | PRKACB | 0.32718334 |
| 90 | PKN1 | 0.32508077 |
| 91 | OBSCN | 0.31505292 |
| 92 | PRKG1 | 0.31375133 |
| 93 | NEK6 | 0.31361911 |
| 94 | CAMK1 | 0.30485619 |
| 95 | EPHA3 | 0.29228975 |
| 96 | TGFBR2 | 0.28423209 |
| 97 | BCKDK | 0.28067494 |
| 98 | PRKCA | 0.27914042 |
| 99 | MYLK | 0.25095442 |
| 100 | LYN | 0.24380658 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.01723683 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.91069093 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.11415109 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.09606279 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.96506893 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.50697336 |
| 7 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.39090644 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.33094341 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.17555336 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.17157647 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.11038845 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.07013803 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.94759427 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.92144449 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.88925064 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.87386089 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.75993130 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.75486650 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.73938127 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.71328903 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.71132933 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.67989683 |
| 23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.65293550 |
| 24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.62328064 |
| 25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.60053501 |
| 26 | Asthma_Homo sapiens_hsa05310 | 1.58334712 |
| 27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.52779879 |
| 28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.51085505 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.47133342 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.42532367 |
| 31 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.41900463 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.40044129 |
| 33 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.37980407 |
| 34 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.36248017 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.33211521 |
| 36 | Base excision repair_Homo sapiens_hsa03410 | 1.31879360 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.25532461 |
| 38 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.19182592 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.18833508 |
| 40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.18047280 |
| 41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.14424073 |
| 42 | Allograft rejection_Homo sapiens_hsa05330 | 1.13324463 |
| 43 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.06578432 |
| 44 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.02205100 |
| 45 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.97863508 |
| 46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.92868613 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92397772 |
| 48 | Taste transduction_Homo sapiens_hsa04742 | 0.88937472 |
| 49 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.88198869 |
| 50 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87462532 |
| 51 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86073833 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84356488 |
| 53 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.80587016 |
| 54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.77581495 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71487101 |
| 56 | Retinol metabolism_Homo sapiens_hsa00830 | 0.71250820 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.69721356 |
| 58 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68102464 |
| 59 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66976575 |
| 60 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.66637115 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.64599307 |
| 62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.62988129 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62668331 |
| 64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62287985 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.60157569 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.59598542 |
| 67 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58375508 |
| 68 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56297577 |
| 69 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53894958 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51898432 |
| 71 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.50611536 |
| 72 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50519118 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50448467 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50217031 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49363013 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48858392 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47815686 |
| 78 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.47181580 |
| 79 | Peroxisome_Homo sapiens_hsa04146 | 0.45915640 |
| 80 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44009516 |
| 81 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.43164308 |
| 82 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.43116615 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41579310 |
| 84 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41560982 |
| 85 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.39661800 |
| 86 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.38158757 |
| 87 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35654675 |
| 88 | Cell cycle_Homo sapiens_hsa04110 | 0.32379107 |
| 89 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.31453278 |
| 90 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.31217268 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28625258 |
| 92 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.25699950 |
| 93 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.25343318 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24887237 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24537813 |
| 96 | Morphine addiction_Homo sapiens_hsa05032 | 0.23877364 |
| 97 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.23490497 |
| 98 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.22071231 |
| 99 | Malaria_Homo sapiens_hsa05144 | 0.20710580 |
| 100 | Carbon metabolism_Homo sapiens_hsa01200 | 0.19015280 |

