FAM63B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)4.36318978
2cellular potassium ion homeostasis (GO:0030007)3.90617512
3behavioral response to nicotine (GO:0035095)3.90475134
4synaptic vesicle maturation (GO:0016188)3.83497904
5locomotory exploration behavior (GO:0035641)3.72900306
6regulation of short-term neuronal synaptic plasticity (GO:0048172)3.59063804
7presynaptic membrane organization (GO:0097090)3.58689531
8nucleobase catabolic process (GO:0046113)3.57781778
9presynaptic membrane assembly (GO:0097105)3.56112717
10neuronal action potential propagation (GO:0019227)3.46341915
11synaptic vesicle exocytosis (GO:0016079)3.45438742
12postsynaptic membrane organization (GO:0001941)3.43194873
13cerebral cortex radially oriented cell migration (GO:0021799)3.37615821
14regulation of synaptic vesicle exocytosis (GO:2000300)3.36388932
15potassium ion import (GO:0010107)3.35162066
16sodium ion export (GO:0071436)3.34364563
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.31888063
18cerebellar Purkinje cell differentiation (GO:0021702)3.31435187
19auditory behavior (GO:0031223)3.23848512
20positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.20919444
21vocalization behavior (GO:0071625)3.17416145
22gamma-aminobutyric acid transport (GO:0015812)3.10295905
23nonmotile primary cilium assembly (GO:0035058)3.08096565
24cerebellar granule cell differentiation (GO:0021707)3.06700439
25layer formation in cerebral cortex (GO:0021819)3.04755058
26ionotropic glutamate receptor signaling pathway (GO:0035235)3.03311782
27positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.03254810
28neurofilament cytoskeleton organization (GO:0060052)3.02307820
29neuron cell-cell adhesion (GO:0007158)3.01244246
30glutamate secretion (GO:0014047)2.98256271
31hindbrain development (GO:0030902)2.97117595
32glutamate receptor signaling pathway (GO:0007215)2.92039584
33regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.91912695
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.91778233
35neurotransmitter secretion (GO:0007269)2.87654434
36regulation of synaptic vesicle transport (GO:1902803)2.86887414
37L-amino acid import (GO:0043092)2.86339650
38regulation of ARF protein signal transduction (GO:0032012)2.85943264
39negative regulation of synaptic transmission, GABAergic (GO:0032229)2.84231295
40retinal ganglion cell axon guidance (GO:0031290)2.83912703
41dendrite morphogenesis (GO:0048813)2.82496710
42gamma-aminobutyric acid signaling pathway (GO:0007214)2.79738157
43cornea development in camera-type eye (GO:0061303)2.79360233
44positive regulation of dendritic spine morphogenesis (GO:0061003)2.79008861
45long-term memory (GO:0007616)2.78900548
46substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.76151472
47substrate-independent telencephalic tangential migration (GO:0021826)2.76151472
48mechanosensory behavior (GO:0007638)2.76070071
49negative regulation of neurotransmitter transport (GO:0051589)2.73986370
50proline transport (GO:0015824)2.73109010
51regulation of cilium movement (GO:0003352)2.68363014
52negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.67981267
53parturition (GO:0007567)2.67873861
54regulation of glutamate receptor signaling pathway (GO:1900449)2.67481936
55potassium ion homeostasis (GO:0055075)2.66972818
56exploration behavior (GO:0035640)2.66630672
57regulation of synapse structural plasticity (GO:0051823)2.66051921
58protein targeting to Golgi (GO:0000042)2.65529451
59cell proliferation in forebrain (GO:0021846)2.64557875
60regulation of voltage-gated calcium channel activity (GO:1901385)2.64145448
61nerve growth factor signaling pathway (GO:0038180)2.64104009
62regulation of meiosis I (GO:0060631)2.64063242
63mating behavior (GO:0007617)2.62511115
64positive regulation of synapse assembly (GO:0051965)2.62489768
65negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.61655426
66negative regulation of translation, ncRNA-mediated (GO:0040033)2.61655426
67regulation of translation, ncRNA-mediated (GO:0045974)2.61655426
68behavioral response to ethanol (GO:0048149)2.60987660
69cell differentiation in hindbrain (GO:0021533)2.57377290
70G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.57161472
71spinal cord development (GO:0021510)2.56149601
72activation of protein kinase A activity (GO:0034199)2.55651818
73regulation of microtubule-based movement (GO:0060632)2.55556068
74relaxation of cardiac muscle (GO:0055119)2.53847838
75regulation of beta-amyloid formation (GO:1902003)2.52802486
76epithelial cilium movement (GO:0003351)2.51039699
77protein localization to cilium (GO:0061512)2.50655072
78negative regulation of cytosolic calcium ion concentration (GO:0051481)2.50543938
79glycine transport (GO:0015816)2.50184911
80neurotransmitter transport (GO:0006836)2.49768481
81regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.49360278
82artery development (GO:0060840)2.49327069
83negative regulation of neurotransmitter secretion (GO:0046929)2.48816670
84retrograde transport, vesicle recycling within Golgi (GO:0000301)2.48722698
85cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.48282741
86regulation of excitatory postsynaptic membrane potential (GO:0060079)2.47871775
87epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.46461166
88clathrin coat assembly (GO:0048268)2.46245075
89transmission of nerve impulse (GO:0019226)2.46221422
90central nervous system projection neuron axonogenesis (GO:0021952)2.46216477
91neuron-neuron synaptic transmission (GO:0007270)2.45701531
92otic vesicle formation (GO:0030916)2.44697746
93establishment of protein localization to Golgi (GO:0072600)2.44390088
94cilium morphogenesis (GO:0060271)2.44246250
95startle response (GO:0001964)2.43990424
96regulation of long-term neuronal synaptic plasticity (GO:0048169)2.43893591
97long-term synaptic potentiation (GO:0060291)2.43792726
98regulation of gene silencing by RNA (GO:0060966)2.43631695
99regulation of posttranscriptional gene silencing (GO:0060147)2.43631695
100regulation of gene silencing by miRNA (GO:0060964)2.43631695
101dendritic spine morphogenesis (GO:0060997)2.42379145
102synaptic transmission, glutamatergic (GO:0035249)2.41919437
103limb development (GO:0060173)2.41774410
104appendage development (GO:0048736)2.41774410
105regulation of telomere maintenance (GO:0032204)2.41655127
106protein localization to synapse (GO:0035418)2.40877831
107intraciliary transport (GO:0042073)2.40507773
108axon ensheathment in central nervous system (GO:0032291)2.39419332
109central nervous system myelination (GO:0022010)2.39419332
110regulation of neurotransmitter secretion (GO:0046928)2.39381275
111protein polyglutamylation (GO:0018095)2.38882182
112regulation of vesicle fusion (GO:0031338)2.36943412
113neuron recognition (GO:0008038)2.36603178
114vesicle transport along microtubule (GO:0047496)2.36112541
115positive regulation of meiosis (GO:0045836)2.35406719
116regulation of postsynaptic membrane potential (GO:0060078)2.34040333
117adult walking behavior (GO:0007628)2.33846107
118receptor recycling (GO:0001881)2.33469717
119detection of calcium ion (GO:0005513)2.33310940
120detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.33047364
121amino acid import (GO:0043090)2.32320452
122multicellular organismal signaling (GO:0035637)2.31832455
123prepulse inhibition (GO:0060134)2.31681791
124protein localization to endosome (GO:0036010)2.31312716
125positive regulation of potassium ion transmembrane transport (GO:1901381)2.31195766
126synapse organization (GO:0050808)2.31191001
127establishment of mitochondrion localization (GO:0051654)2.30801729
128kidney morphogenesis (GO:0060993)2.30233620
129reflex (GO:0060004)2.30163098
130regulation of cell communication by electrical coupling (GO:0010649)2.29762963
131negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.28902158
132negative regulation of cell killing (GO:0031342)2.28902158
133inner ear receptor stereocilium organization (GO:0060122)2.28825328
134establishment of nucleus localization (GO:0040023)2.28441275
135regulation of non-canonical Wnt signaling pathway (GO:2000050)2.28084666
136axon cargo transport (GO:0008088)2.27953573
137regulation of neuronal synaptic plasticity (GO:0048168)2.27869409
138sex differentiation (GO:0007548)2.27632389
139regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.27450230
140neurotransmitter-gated ion channel clustering (GO:0072578)2.27268110
141cell migration in hindbrain (GO:0021535)2.26855483
142regulation of membrane repolarization (GO:0060306)2.25828652
143synapse assembly (GO:0007416)2.25256043
144dorsal/ventral axis specification (GO:0009950)2.25106439
145short-term memory (GO:0007614)2.25019258
146positive regulation of meiotic cell cycle (GO:0051446)2.24306303
147membrane depolarization during action potential (GO:0086010)2.23970192
148neuron migration (GO:0001764)2.23848575
149regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.23653546
150regulation of neurotransmitter levels (GO:0001505)2.23540019
151long term synaptic depression (GO:0060292)2.23057595
152positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.21116907
153retina layer formation (GO:0010842)2.20968612
154retinal cone cell development (GO:0046549)2.20895423
155positive regulation of potassium ion transport (GO:0043268)2.20880954
156membrane depolarization (GO:0051899)2.20005501
157regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.19225624
158regulation of clathrin-mediated endocytosis (GO:2000369)2.18162373
159regulation of neurotransmitter transport (GO:0051588)2.17952048
160cellular sodium ion homeostasis (GO:0006883)2.15600993
161positive regulation of membrane potential (GO:0045838)2.15083281
162synaptic vesicle endocytosis (GO:0048488)2.15061766
163regulation of synaptic transmission, glutamatergic (GO:0051966)2.14865961
164regulation of amyloid precursor protein catabolic process (GO:1902991)2.14481026
165regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.14322520
166axonal fasciculation (GO:0007413)2.13858402
167regulation of synaptic transmission, GABAergic (GO:0032228)2.13301775
168response to pheromone (GO:0019236)2.13109345

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.53179464
2GBX2_23144817_ChIP-Seq_PC3_Human2.67257447
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47824901
4VDR_22108803_ChIP-Seq_LS180_Human2.39179519
5ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.39040715
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.30292538
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.22151121
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.21795246
9NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.15456668
10SALL1_21062744_ChIP-ChIP_HESCs_Human2.13573573
11EWS_26573619_Chip-Seq_HEK293_Human2.06920792
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.04655360
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.03445486
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.03445486
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.03180888
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.01382005
17FUS_26573619_Chip-Seq_HEK293_Human1.99806341
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.95645055
19AR_21572438_ChIP-Seq_LNCaP_Human1.94478628
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.93451282
21DROSHA_22980978_ChIP-Seq_HELA_Human1.92793862
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.90149411
23RBPJ_22232070_ChIP-Seq_NCS_Mouse1.86372137
24SMAD_19615063_ChIP-ChIP_OVARY_Human1.85799028
25JARID2_20075857_ChIP-Seq_MESCs_Mouse1.79651605
26RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72280123
27BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70022691
28TAF15_26573619_Chip-Seq_HEK293_Human1.69469890
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.67913500
30RNF2_27304074_Chip-Seq_NSC_Mouse1.66491358
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.64947511
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.63063311
33ZNF217_24962896_ChIP-Seq_MCF-7_Human1.62633561
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.61643648
35SUZ12_27294783_Chip-Seq_ESCs_Mouse1.61290614
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61104941
37CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59337630
38* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.58839414
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.58073361
40SMAD4_21799915_ChIP-Seq_A2780_Human1.51413203
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.50706060
42REST_21632747_ChIP-Seq_MESCs_Mouse1.50124892
43FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.46366722
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44890410
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40563079
46IKZF1_21737484_ChIP-ChIP_HCT116_Human1.39827410
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39594819
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.38194237
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37971972
50IRF1_19129219_ChIP-ChIP_H3396_Human1.37379186
51RARB_27405468_Chip-Seq_BRAIN_Mouse1.36828752
52STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.36180454
53FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.35521084
54* P300_19829295_ChIP-Seq_ESCs_Human1.35488587
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35171047
56CBP_20019798_ChIP-Seq_JUKART_Human1.35171047
57TP53_16413492_ChIP-PET_HCT116_Human1.34416650
58ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33976906
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.33844178
60AHR_22903824_ChIP-Seq_MCF-7_Human1.32923434
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.32785480
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.31871722
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31357526
64MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30702609
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29586285
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.28472050
67ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28072518
68AR_25329375_ChIP-Seq_VCAP_Human1.24267838
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23442701
70CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23349038
71GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22698406
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.22042278
73CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21355136
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20823291
75BCAT_22108803_ChIP-Seq_LS180_Human1.20465680
76TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.19948131
77STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19512057
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19075159
79STAT3_23295773_ChIP-Seq_U87_Human1.18694679
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.17973882
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17903460
82RXR_22108803_ChIP-Seq_LS180_Human1.17167836
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.16560690
84TP53_18474530_ChIP-ChIP_U2OS_Human1.16532336
85BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.16014351
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.15740638
87RUNX_20019798_ChIP-Seq_JUKART_Human1.13299315
88JUN_21703547_ChIP-Seq_K562_Human1.13086342
89IGF1R_20145208_ChIP-Seq_DFB_Human1.12675833
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.12664548
91NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12554106
92NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12554106
93WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12266810
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.11831591
95SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11829046
96BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.11531129
97SMAD3_21741376_ChIP-Seq_ESCs_Human1.11354899
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10859273
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.10065323
100EP300_21415370_ChIP-Seq_HL-1_Mouse1.09937467
101LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08780113
102HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08286297
103TCF4_22108803_ChIP-Seq_LS180_Human1.07358808
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07202464
105ER_23166858_ChIP-Seq_MCF-7_Human1.05505995
106REST_18959480_ChIP-ChIP_MESCs_Mouse1.05331077
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05330006
108GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05078939
109* SMAD4_21741376_ChIP-Seq_EPCs_Human1.04581365
110TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.04202437
111TCF4_23295773_ChIP-Seq_U87_Human1.02675070
112P53_22387025_ChIP-Seq_ESCs_Mouse1.02263543
113PRDM14_20953172_ChIP-Seq_ESCs_Human1.00104982
114TRIM28_21343339_ChIP-Seq_HEK293_Human0.99239548
115AR_19668381_ChIP-Seq_PC3_Human0.99084988
116PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98357822
117ESR1_20079471_ChIP-ChIP_T-47D_Human0.98213769
118Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.98099139
119TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97339888
120ZNF274_21170338_ChIP-Seq_K562_Hela0.95903648
121RUNX2_22187159_ChIP-Seq_PCA_Human0.95588178
122YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93114062
123KDM2B_26808549_Chip-Seq_K562_Human0.92697828
124SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91811030
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.90619153
126GATA2_21666600_ChIP-Seq_HMVEC_Human0.90152067
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89671593
128TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89428940
129VDR_24787735_ChIP-Seq_THP-1_Human0.89421697
130TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88791134
131CBX2_27304074_Chip-Seq_ESCs_Mouse0.87968212
132NANOG_18555785_Chip-Seq_ESCs_Mouse0.87758011
133RING1B_27294783_Chip-Seq_ESCs_Mouse0.87730604
134SMAD4_21741376_ChIP-Seq_HESCs_Human0.87025447
135TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86113014
136POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.86113014
137P53_22127205_ChIP-Seq_FIBROBLAST_Human0.86084630

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.01558408
2MP0009046_muscle_twitch3.06431942
3MP0003635_abnormal_synaptic_transmissio3.02377603
4MP0004270_analgesia2.80811768
5MP0003880_abnormal_central_pattern2.74836447
6MP0002064_seizures2.55995068
7MP0009745_abnormal_behavioral_response2.46908394
8MP0006292_abnormal_olfactory_placode2.45789802
9MP0008569_lethality_at_weaning2.30554693
10MP0008877_abnormal_DNA_methylation2.26785491
11MP0003121_genomic_imprinting2.26640751
12MP0001968_abnormal_touch/_nociception2.26553400
13MP0003890_abnormal_embryonic-extraembry2.26445537
14MP0002063_abnormal_learning/memory/cond2.23795378
15MP0002272_abnormal_nervous_system2.22890799
16MP0002734_abnormal_mechanical_nocicepti2.21107677
17MP0005423_abnormal_somatic_nervous2.20792381
18MP0009780_abnormal_chondrocyte_physiolo2.16955037
19MP0002102_abnormal_ear_morphology2.12659975
20MP0003122_maternal_imprinting2.06100294
21MP0001486_abnormal_startle_reflex2.03636190
22MP0002572_abnormal_emotion/affect_behav2.03000810
23MP0005171_absent_coat_pigmentation2.01038892
24MP0000920_abnormal_myelination1.96408836
25MP0003690_abnormal_glial_cell1.92821035
26MP0001984_abnormal_olfaction1.90814286
27MP0002067_abnormal_sensory_capabilities1.90398235
28MP0004133_heterotaxia1.80440708
29MP0001501_abnormal_sleep_pattern1.78851213
30MP0002735_abnormal_chemical_nociception1.78479038
31MP0000569_abnormal_digit_pigmentation1.72178810
32MP0000372_irregular_coat_pigmentation1.71180324
33MP0004885_abnormal_endolymph1.69269156
34MP0002938_white_spotting1.63163221
35MP0002733_abnormal_thermal_nociception1.62837878
36MP0001970_abnormal_pain_threshold1.62757578
37MP0001440_abnormal_grooming_behavior1.62452854
38MP0002736_abnormal_nociception_after1.62306504
39MP0003633_abnormal_nervous_system1.58769810
40MP0002909_abnormal_adrenal_gland1.56828102
41MP0001986_abnormal_taste_sensitivity1.53310084
42MP0002184_abnormal_innervation1.50046836
43MP0004510_myositis1.49994684
44MP0005386_behavior/neurological_phenoty1.47718014
45MP0004924_abnormal_behavior1.47718014
46MP0003329_amyloid_beta_deposits1.46393411
47MP0004742_abnormal_vestibular_system1.42321938
48MP0005645_abnormal_hypothalamus_physiol1.41537225
49MP0001529_abnormal_vocalization1.39237959
50MP0000631_abnormal_neuroendocrine_gland1.35016880
51MP0000013_abnormal_adipose_tissue1.33857420
52MP0002557_abnormal_social/conspecific_i1.33812683
53MP0004484_altered_response_of1.32829183
54MP0005551_abnormal_eye_electrophysiolog1.32448977
55MP0000778_abnormal_nervous_system1.31841182
56MP0002090_abnormal_vision1.30928184
57MP0003937_abnormal_limbs/digits/tail_de1.29469337
58MP0003634_abnormal_glial_cell1.28704328
59MP0003300_gastrointestinal_ulcer1.26337311
60MP0003631_nervous_system_phenotype1.26276235
61MP0005409_darkened_coat_color1.25917430
62MP0001485_abnormal_pinna_reflex1.23902582
63MP0005499_abnormal_olfactory_system1.23298912
64MP0005394_taste/olfaction_phenotype1.23298912
65MP0003646_muscle_fatigue1.22443705
66MP0005187_abnormal_penis_morphology1.21345666
67MP0003045_fibrosis1.18650990
68MP0002752_abnormal_somatic_nervous1.17591583
69MP0004130_abnormal_muscle_cell1.17114224
70MP0003123_paternal_imprinting1.15793332
71MP0004215_abnormal_myocardial_fiber1.15591191
72MP0004147_increased_porphyrin_level1.14608969
73MP0002229_neurodegeneration1.14428921
74MP0003183_abnormal_peptide_metabolism1.14256605
75MP0003136_yellow_coat_color1.13172623
76MP0000427_abnormal_hair_cycle1.11687347
77MP0003119_abnormal_digestive_system1.11511064
78MP0004811_abnormal_neuron_physiology1.11052562
79MP0008789_abnormal_olfactory_epithelium1.10739735
80MP0002160_abnormal_reproductive_system1.10231364
81MP0002066_abnormal_motor_capabilities/c1.10072334
82MP0001293_anophthalmia1.09986000
83MP0004145_abnormal_muscle_electrophysio1.09424589
84MP0006072_abnormal_retinal_apoptosis1.08525852
85MP0002882_abnormal_neuron_morphology1.06804545
86MP0004858_abnormal_nervous_system1.06657329
87MP0010234_abnormal_vibrissa_follicle1.06395212
88MP0003567_abnormal_fetal_cardiomyocyte1.06048003
89MP0004043_abnormal_pH_regulation1.04961126
90MP0000955_abnormal_spinal_cord1.02731887
91MP0003303_peritoneal_inflammation1.02065254
92MP0008775_abnormal_heart_ventricle1.01268519
93MP0001502_abnormal_circadian_rhythm1.01098125
94MP0005253_abnormal_eye_physiology1.00455056
95MP0000604_amyloidosis0.99417236
96MP0002877_abnormal_melanocyte_morpholog0.99008905
97MP0002837_dystrophic_cardiac_calcinosis0.98597981
98MP0005535_abnormal_body_temperature0.98535496
99MP0001299_abnormal_eye_distance/0.98215909
100MP0005167_abnormal_blood-brain_barrier0.97819596
101MP0005195_abnormal_posterior_eye0.97715652
102MP0000566_synostosis0.97442317
103MP0003861_abnormal_nervous_system0.97334893
104MP0000647_abnormal_sebaceous_gland0.96925639
105MP0006276_abnormal_autonomic_nervous0.96753301
106MP0003632_abnormal_nervous_system0.96031674
107MP0002233_abnormal_nose_morphology0.95001809
108MP0001188_hyperpigmentation0.94242979
109MP0004142_abnormal_muscle_tone0.93870325
110MP0000049_abnormal_middle_ear0.93555827
111MP0010386_abnormal_urinary_bladder0.91660283
112MP0001879_abnormal_lymphatic_vessel0.91456873
113MP0000026_abnormal_inner_ear0.91112173
114MP0002638_abnormal_pupillary_reflex0.89377875
115MP0008874_decreased_physiological_sensi0.87899991
116MP0003172_abnormal_lysosome_physiology0.86930861
117MP0005058_abnormal_lysosome_morphology0.84891953
118MP0003075_altered_response_to0.84634662
119MP0002653_abnormal_ependyma_morphology0.84245051
120MP0004085_abnormal_heartbeat0.83663667
121MP0001286_abnormal_eye_development0.81986216
122MP0003942_abnormal_urinary_system0.81763841
123MP0000015_abnormal_ear_pigmentation0.81652569
124MP0003755_abnormal_palate_morphology0.81600881
125MP0003938_abnormal_ear_development0.80536723
126MP0003283_abnormal_digestive_organ0.80157792
127MP0008872_abnormal_physiological_respon0.78844042
128MP0004036_abnormal_muscle_relaxation0.78814740
129MP0002009_preneoplasia0.78216580
130MP0002998_abnormal_bone_remodeling0.76653067
131MP0000751_myopathy0.76275610
132MP0005646_abnormal_pituitary_gland0.76197400
133MP0003879_abnormal_hair_cell0.75626247
134MP0001177_atelectasis0.75104331
135MP0003385_abnormal_body_wall0.74072788
136MP0002972_abnormal_cardiac_muscle0.72225186
137MP0002822_catalepsy0.69925325
138MP0001905_abnormal_dopamine_level0.69188613
139MP0001851_eye_inflammation0.69134076
140MP0008961_abnormal_basal_metabolism0.68456980
141MP0003787_abnormal_imprinting0.68222396
142MP0001963_abnormal_hearing_physiology0.66226123
143MP0002152_abnormal_brain_morphology0.64146870
144MP0001958_emphysema0.63899656

Predicted human phenotypes

RankGene SetZ-score
1Action tremor (HP:0002345)4.64317366
2Focal motor seizures (HP:0011153)4.39993017
3Progressive cerebellar ataxia (HP:0002073)4.17445323
4Atonic seizures (HP:0010819)3.98476959
5Focal seizures (HP:0007359)3.97902093
6Visual hallucinations (HP:0002367)3.82274043
7Febrile seizures (HP:0002373)3.81006251
8Molar tooth sign on MRI (HP:0002419)3.74429086
9Abnormality of midbrain morphology (HP:0002418)3.74429086
10Supranuclear gaze palsy (HP:0000605)3.65246231
11Nephronophthisis (HP:0000090)3.50463366
12Myokymia (HP:0002411)3.37176946
13Abnormality of binocular vision (HP:0011514)3.33783489
14Diplopia (HP:0000651)3.33783489
15Truncal ataxia (HP:0002078)3.33405311
16Epileptic encephalopathy (HP:0200134)3.26026283
17Pancreatic fibrosis (HP:0100732)3.22596921
18Absence seizures (HP:0002121)3.18704170
19Intention tremor (HP:0002080)3.12487060
20Neurofibrillary tangles (HP:0002185)3.10203828
21Pancreatic cysts (HP:0001737)3.09991355
22Gaze-evoked nystagmus (HP:0000640)3.08863393
23Medial flaring of the eyebrow (HP:0010747)3.05491007
24Gait imbalance (HP:0002141)3.05159220
25Broad-based gait (HP:0002136)3.00942149
26True hermaphroditism (HP:0010459)2.96348882
27Abnormality of the renal medulla (HP:0100957)2.94035374
28Dialeptic seizures (HP:0011146)2.88256638
29Abnormality of the labia minora (HP:0012880)2.86605324
30Papilledema (HP:0001085)2.86173982
31Generalized tonic-clonic seizures (HP:0002069)2.85025354
32Dysdiadochokinesis (HP:0002075)2.83918553
33Blue irides (HP:0000635)2.83793396
34Tubular atrophy (HP:0000092)2.76740545
35Dysmetria (HP:0001310)2.76198525
36Agitation (HP:0000713)2.70887997
37Genetic anticipation (HP:0003743)2.70158883
38Congenital primary aphakia (HP:0007707)2.68179604
39Scanning speech (HP:0002168)2.67561656
40Cerebral inclusion bodies (HP:0100314)2.64449911
41Vaginal atresia (HP:0000148)2.63275176
42Genital tract atresia (HP:0001827)2.62058280
43Hyperventilation (HP:0002883)2.61845421
44Mutism (HP:0002300)2.59287984
45Volvulus (HP:0002580)2.57517212
46Progressive inability to walk (HP:0002505)2.52945884
47Termporal pattern (HP:0011008)2.51799947
48Insidious onset (HP:0003587)2.51799947
49Postural instability (HP:0002172)2.50708008
50Anxiety (HP:0000739)2.49841280
51Dysmetric saccades (HP:0000641)2.48887438
52Nephrogenic diabetes insipidus (HP:0009806)2.48849323
53Excessive salivation (HP:0003781)2.46962189
54Drooling (HP:0002307)2.46962189
55Ankle clonus (HP:0011448)2.45167799
56Megalencephaly (HP:0001355)2.44157268
57Depression (HP:0000716)2.43927102
58Postural tremor (HP:0002174)2.42358373
59Hemiplegia (HP:0002301)2.39502714
60Hemiparesis (HP:0001269)2.32404144
61Protruding tongue (HP:0010808)2.31834041
62Pheochromocytoma (HP:0002666)2.31020736
63Lissencephaly (HP:0001339)2.30004022
64Abnormality of the corticospinal tract (HP:0002492)2.28505515
65Abnormality of the renal cortex (HP:0011035)2.28256409
66Polyphagia (HP:0002591)2.26918359
67Impaired smooth pursuit (HP:0007772)2.24960255
68Macroorchidism (HP:0000053)2.24435397
69Neuronal loss in central nervous system (HP:0002529)2.22892315
70Poor coordination (HP:0002370)2.19123725
71Aqueductal stenosis (HP:0002410)2.17798031
72Congenital stationary night blindness (HP:0007642)2.14469649
73Increased cerebral lipofuscin (HP:0011813)2.11203617
74Urinary bladder sphincter dysfunction (HP:0002839)2.10692404
75Optic nerve hypoplasia (HP:0000609)2.09420670
76Impaired social interactions (HP:0000735)2.08629142
77Abnormal social behavior (HP:0012433)2.08629142
78Type II lissencephaly (HP:0007260)2.07583803
79Onion bulb formation (HP:0003383)2.07541060
80Lower limb asymmetry (HP:0100559)2.06906325
81Chronic hepatic failure (HP:0100626)2.06445814
82Abnormal eating behavior (HP:0100738)2.05045637
83Poor eye contact (HP:0000817)2.04699383
84Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.02576265
85Arterial tortuosity (HP:0005116)2.02398578
86Abnormality of saccadic eye movements (HP:0000570)2.02025178
87Specific learning disability (HP:0001328)2.01921548
88Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.00722553
89Inability to walk (HP:0002540)2.00721427
90Psychosis (HP:0000709)1.99596923
91Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.98949007
92Degeneration of the lateral corticospinal tracts (HP:0002314)1.98949007
93Abnormality of salivation (HP:0100755)1.97072107
94Pachygyria (HP:0001302)1.96721431
95Clumsiness (HP:0002312)1.96072449
96Anencephaly (HP:0002323)1.95329502
97Polydipsia (HP:0001959)1.94931532
98Abnormal drinking behavior (HP:0030082)1.94931532
99Cystic liver disease (HP:0006706)1.94460378
100Labial hypoplasia (HP:0000066)1.94192318
101Aplasia/Hypoplasia of the tongue (HP:0010295)1.94081862
102Abnormality of ocular smooth pursuit (HP:0000617)1.93703484
103Thickened helices (HP:0000391)1.93703441
104Inappropriate behavior (HP:0000719)1.93121194
105Metabolic alkalosis (HP:0200114)1.91945227
106Hepatoblastoma (HP:0002884)1.91807773
107Widely spaced teeth (HP:0000687)1.90126246
108Exotropia (HP:0000577)1.88741225
109Renal cortical cysts (HP:0000803)1.88090736
110Vascular tortuosity (HP:0004948)1.87678144
111Scrotal hypoplasia (HP:0000046)1.86480115
112Cerebral hemorrhage (HP:0001342)1.86380100
113Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.85914770
114Aplasia of the phalanges of the hand (HP:0009802)1.85689736
115Aplasia involving bones of the extremities (HP:0009825)1.85689736
116Aplasia involving bones of the upper limbs (HP:0009823)1.85689736
117Stereotypic behavior (HP:0000733)1.84967817
118Bifid tongue (HP:0010297)1.84715708
119Increased corneal curvature (HP:0100692)1.84202219
120Keratoconus (HP:0000563)1.84202219
121Aplasia/Hypoplasia of the tibia (HP:0005772)1.83730356
122Hypokalemic alkalosis (HP:0001949)1.83578910
123Narrow forehead (HP:0000341)1.82820475
124Spastic gait (HP:0002064)1.82480162
125Colon cancer (HP:0003003)1.82421037
126Postaxial hand polydactyly (HP:0001162)1.82293611
127Neuroendocrine neoplasm (HP:0100634)1.81948590
128Limb dystonia (HP:0002451)1.81940566
129Hematochezia (HP:0002573)1.81824829
130Epileptiform EEG discharges (HP:0011182)1.81162599
131Oligodactyly (hands) (HP:0001180)1.79232887
132Abnormal respiratory motile cilium morphology (HP:0005938)1.78468774
133Abnormal respiratory epithelium morphology (HP:0012253)1.78468774
134Hypsarrhythmia (HP:0002521)1.78157258
135Gait ataxia (HP:0002066)1.77964016
136Sclerocornea (HP:0000647)1.77846389
137Anophthalmia (HP:0000528)1.76603935
138Retinal dysplasia (HP:0007973)1.76033884
139Absent speech (HP:0001344)1.75817773
140Morphological abnormality of the pyramidal tract (HP:0002062)1.74848332
141EEG with generalized epileptiform discharges (HP:0011198)1.74649593
142Postaxial foot polydactyly (HP:0001830)1.74291770
143Small hand (HP:0200055)1.73746158
144Increased neuronal autofluorescent lipopigment (HP:0002074)1.73631675
145Hypoplastic female external genitalia (HP:0012815)1.72453314
146Growth hormone deficiency (HP:0000824)1.70906052
147Peripheral hypomyelination (HP:0007182)1.70892180
148Short foot (HP:0001773)1.69375613
149Increased CSF protein (HP:0002922)1.69193081
150Hypoplasia of the iris (HP:0007676)1.68737081
151Rigidity (HP:0002063)1.67744523
152Broad foot (HP:0001769)1.67619728
153Urinary urgency (HP:0000012)1.66656847
154Status epilepticus (HP:0002133)1.66561231
155Impaired vibration sensation in the lower limbs (HP:0002166)1.66227668
156Cutaneous finger syndactyly (HP:0010554)1.66059481
157Rapidly progressive (HP:0003678)1.65732435
158Micropenis (HP:0000054)1.65444858
159Akinesia (HP:0002304)1.64242480
160Lower limb muscle weakness (HP:0007340)1.63891096
161Septo-optic dysplasia (HP:0100842)1.63430713
162Slow saccadic eye movements (HP:0000514)1.63239722
163Spastic tetraplegia (HP:0002510)1.63153675
164Aplasia/Hypoplasia of the lens (HP:0008063)1.62862533
165Abnormality of macular pigmentation (HP:0008002)1.61859521
166Intestinal atresia (HP:0011100)1.61666066
167Polyuria (HP:0000103)1.61283164
168Abnormal pancreas size (HP:0012094)1.58554469
169Hypoplasia of the fovea (HP:0007750)1.57909936
170Aplasia/Hypoplasia of the fovea (HP:0008060)1.57909936
171Fair hair (HP:0002286)1.57831767
172Prominent nasal bridge (HP:0000426)1.57509297
173Abnormality of the fovea (HP:0000493)1.56153759

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK32.72166218
2RIPK42.54681219
3NTRK32.52640535
4MAP3K92.16583547
5MAP3K42.09428438
6RIPK12.04827029
7NTRK21.90698195
8WNK11.87632439
9MARK11.82968718
10CAMKK21.81908069
11DYRK21.81874101
12CAMK1G1.80796060
13MAP4K21.80675980
14MAP3K21.77487021
15LATS11.73019948
16PINK11.69451228
17FGFR21.67016801
18NUAK11.64433114
19ACVR1B1.57375671
20STK391.57024721
21NTRK11.55061668
22GRK51.54700750
23SGK4941.53046120
24SGK2231.53046120
25MAP2K71.48950378
26SGK21.48337395
27PRKCH1.44187555
28MINK11.43544732
29OXSR11.38876616
30BCR1.36864040
31FRK1.34259872
32ADRBK21.33553611
33MAP2K41.33083632
34SGK31.32932225
35CAMKK11.31565474
36SIK21.31123699
37PHKG21.28288444
38PHKG11.28288444
39PAK61.27521452
40STK38L1.25834665
41RET1.24422164
42GRK11.21687529
43DAPK21.21097714
44MAPKAPK51.15647513
45HIPK21.14566252
46CDK51.13945648
47EPHB11.12884031
48CAMK1D1.08265842
49AKT31.07282597
50NEK21.07247341
51TLK11.07018946
52MKNK21.04544326
53TRIM281.04397267
54FGFR31.03695296
55INSRR0.99515614
56CASK0.98169112
57STK110.96678276
58FES0.96285854
59KSR20.95947834
60WNK40.95316210
61MAP3K120.92975511
62JAK10.92656587
63PKN10.92594291
64PLK20.91227163
65TNIK0.88302347
66STK30.86979669
67PRKCE0.86198046
68PDK10.85851084
69MST1R0.84928604
70PRPF4B0.83756523
71ADRBK10.83026019
72WEE10.82764770
73MAP3K130.82107974
74MAPK130.80983553
75EPHB20.79742624
76NEK10.79711658
77SGK10.79672078
78MAPK120.78586721
79PLK40.78128729
80MARK20.77846686
81PDPK10.77600664
82TRIB30.76964580
83UHMK10.76797616
84ZAK0.76387989
85CAMK2A0.76112913
86TGFBR10.75627043
87CAMK2D0.75386914
88BMPR20.74561271
89TIE10.74311989
90CSNK1G20.74139210
91GRK70.72630267
92CAMK2B0.72552861
93PNCK0.72154546
94FYN0.71688669
95TGFBR20.71253680
96DYRK30.69611654
97PRKD10.69481589
98ITK0.69369546
99FGR0.69045660
100EPHA40.68965823
101CAMK10.68506517
102PAK30.67682881
103LMTK20.64305892
104PRKCQ0.63854218
105ROCK20.62396066
106CSNK1G10.61035936
107TYRO30.60531072
108DYRK1A0.59922556
109TNK20.59275280
110DMPK0.58874561
111PRKCG0.58804057
112SCYL20.57714041
113BRSK20.57580984
114SYK0.56685004
115OBSCN0.56538828
116CDK190.56307894
117PDGFRB0.55992028
118CSNK1E0.53999887
119JAK20.53744766
120CSNK1A1L0.53089658
121BMPR1B0.52491851
122PLK30.51985067
123MAP3K70.50771716
124MAP3K10.50383094
125PRKACA0.50330970
126STK380.49828486
127CDK90.48084279
128PIK3CA0.46851420
129PTK2B0.46710623
130KSR10.45946758
131PRKG10.45907192
132ERBB30.45766739
133CDC70.45532805
134EPHA30.45475268
135CSNK1D0.45186732
136CAMK40.44774140
137LATS20.43882642
138FER0.43204720
139CDK30.42923957
140STK160.41928798
141CSNK1G30.40550727
142MAP3K50.37626471
143MAP2K60.37325230
144PLK10.37075681
145DYRK1B0.36634659
146ERBB20.35379976

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.18566569
2Synaptic vesicle cycle_Homo sapiens_hsa047212.02612427
3GABAergic synapse_Homo sapiens_hsa047271.97561481
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.96873506
5Glutamatergic synapse_Homo sapiens_hsa047241.96599564
6Olfactory transduction_Homo sapiens_hsa047401.92633808
7Morphine addiction_Homo sapiens_hsa050321.90375369
8Circadian entrainment_Homo sapiens_hsa047131.86084107
9Long-term potentiation_Homo sapiens_hsa047201.84246996
10Salivary secretion_Homo sapiens_hsa049701.82274466
11Gastric acid secretion_Homo sapiens_hsa049711.66786018
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.65939376
13Long-term depression_Homo sapiens_hsa047301.61659740
14Oxidative phosphorylation_Homo sapiens_hsa001901.61361049
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60015354
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.54210475
17Renin secretion_Homo sapiens_hsa049241.53550526
18Taste transduction_Homo sapiens_hsa047421.52606340
19Basal transcription factors_Homo sapiens_hsa030221.51253623
20Dopaminergic synapse_Homo sapiens_hsa047281.50477292
21Insulin secretion_Homo sapiens_hsa049111.50095609
22Cholinergic synapse_Homo sapiens_hsa047251.46710372
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.46708974
24Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.45531104
25Amphetamine addiction_Homo sapiens_hsa050311.37810751
26Ether lipid metabolism_Homo sapiens_hsa005651.36739734
27Linoleic acid metabolism_Homo sapiens_hsa005911.35976139
28Steroid biosynthesis_Homo sapiens_hsa001001.33918580
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.33870486
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32935595
31Serotonergic synapse_Homo sapiens_hsa047261.32408209
32Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.32311839
33Parkinsons disease_Homo sapiens_hsa050121.31833453
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.29652889
35Dorso-ventral axis formation_Homo sapiens_hsa043201.27997627
36Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.26519847
37Hippo signaling pathway_Homo sapiens_hsa043901.23889965
38Type II diabetes mellitus_Homo sapiens_hsa049301.23228701
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.23111973
40Basal cell carcinoma_Homo sapiens_hsa052171.22547878
41Collecting duct acid secretion_Homo sapiens_hsa049661.21908140
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.21774681
43Oxytocin signaling pathway_Homo sapiens_hsa049211.20334311
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.17326144
45GnRH signaling pathway_Homo sapiens_hsa049121.15538326
46Hedgehog signaling pathway_Homo sapiens_hsa043401.15358216
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.14742952
48Butanoate metabolism_Homo sapiens_hsa006501.13760309
49Calcium signaling pathway_Homo sapiens_hsa040201.13144695
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.12655990
51Phototransduction_Homo sapiens_hsa047441.11633555
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.08381024
53cAMP signaling pathway_Homo sapiens_hsa040241.06986297
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06938289
55Pancreatic secretion_Homo sapiens_hsa049721.05202388
56Propanoate metabolism_Homo sapiens_hsa006401.04315661
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04077788
58Protein export_Homo sapiens_hsa030601.03985311
59Cocaine addiction_Homo sapiens_hsa050301.02844054
60Estrogen signaling pathway_Homo sapiens_hsa049151.02080390
61cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00817026
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.99923769
63Nitrogen metabolism_Homo sapiens_hsa009100.99421951
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.98307636
65Fanconi anemia pathway_Homo sapiens_hsa034600.97845217
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97034773
67Alzheimers disease_Homo sapiens_hsa050100.97017029
68Ovarian steroidogenesis_Homo sapiens_hsa049130.96491399
69Glioma_Homo sapiens_hsa052140.95902748
70Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.94860030
71Huntingtons disease_Homo sapiens_hsa050160.93351367
72Selenocompound metabolism_Homo sapiens_hsa004500.93234544
73RNA degradation_Homo sapiens_hsa030180.90513122
74Gap junction_Homo sapiens_hsa045400.90280727
75Vascular smooth muscle contraction_Homo sapiens_hsa042700.87817228
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87162130
77Wnt signaling pathway_Homo sapiens_hsa043100.85921296
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85567328
79Thyroid hormone synthesis_Homo sapiens_hsa049180.83808518
80ErbB signaling pathway_Homo sapiens_hsa040120.82981649
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.81887424
82Chemokine signaling pathway_Homo sapiens_hsa040620.81371779
83Axon guidance_Homo sapiens_hsa043600.80594493
84Renal cell carcinoma_Homo sapiens_hsa052110.80130595
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79304487
86Dilated cardiomyopathy_Homo sapiens_hsa054140.78165975
87Regulation of autophagy_Homo sapiens_hsa041400.76082101
88Choline metabolism in cancer_Homo sapiens_hsa052310.75264055
89Inositol phosphate metabolism_Homo sapiens_hsa005620.75140999
90Circadian rhythm_Homo sapiens_hsa047100.75031788
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74505869
92B cell receptor signaling pathway_Homo sapiens_hsa046620.74490489
93Melanogenesis_Homo sapiens_hsa049160.73284796
94Platelet activation_Homo sapiens_hsa046110.72131339
95Endocytosis_Homo sapiens_hsa041440.71752985
96Osteoclast differentiation_Homo sapiens_hsa043800.71407761
97Rheumatoid arthritis_Homo sapiens_hsa053230.70986341
98Vibrio cholerae infection_Homo sapiens_hsa051100.70517019
99MAPK signaling pathway_Homo sapiens_hsa040100.69942154
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.69913285
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.69361922
102TGF-beta signaling pathway_Homo sapiens_hsa043500.68731775
103Oocyte meiosis_Homo sapiens_hsa041140.65304291
104ECM-receptor interaction_Homo sapiens_hsa045120.65188057
105Cardiac muscle contraction_Homo sapiens_hsa042600.64930186
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.64875428
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.64741966
108Ras signaling pathway_Homo sapiens_hsa040140.64308517
109Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63818634
110VEGF signaling pathway_Homo sapiens_hsa043700.63118054
111Tight junction_Homo sapiens_hsa045300.62515181
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62394152
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62255690
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62096761
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61754601
116Lysosome_Homo sapiens_hsa041420.58995235
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58480695
118Rap1 signaling pathway_Homo sapiens_hsa040150.57943324
119Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55426586
120Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53515305
121Tuberculosis_Homo sapiens_hsa051520.52487507
122Sphingolipid metabolism_Homo sapiens_hsa006000.51343083
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51325584
124Melanoma_Homo sapiens_hsa052180.50918316
125African trypanosomiasis_Homo sapiens_hsa051430.50657954
126Alcoholism_Homo sapiens_hsa050340.50614293
127Fatty acid biosynthesis_Homo sapiens_hsa000610.49774952
128Peroxisome_Homo sapiens_hsa041460.49680647
129Tryptophan metabolism_Homo sapiens_hsa003800.49290705
130AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49183560
131Caffeine metabolism_Homo sapiens_hsa002320.49137947
132Phagosome_Homo sapiens_hsa041450.48414035
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47647355
134Pancreatic cancer_Homo sapiens_hsa052120.47257915
135Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47115038
136ABC transporters_Homo sapiens_hsa020100.47076631
137Mineral absorption_Homo sapiens_hsa049780.47002735
138Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46942805
139Homologous recombination_Homo sapiens_hsa034400.46660236
140Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46004421
141Non-small cell lung cancer_Homo sapiens_hsa052230.45931569
142Endometrial cancer_Homo sapiens_hsa052130.45017381
143mTOR signaling pathway_Homo sapiens_hsa041500.44304511
144Prolactin signaling pathway_Homo sapiens_hsa049170.44236489
145T cell receptor signaling pathway_Homo sapiens_hsa046600.43778666
146Adipocytokine signaling pathway_Homo sapiens_hsa049200.43673437
147Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43523325
148beta-Alanine metabolism_Homo sapiens_hsa004100.41733348
149RNA polymerase_Homo sapiens_hsa030200.41730664

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »