FAM81B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of cilium movement (GO:0003352)9.77189690
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.84952750
3motile cilium assembly (GO:0044458)8.51973251
4sensory perception of chemical stimulus (GO:0007606)8.42989662
5axoneme assembly (GO:0035082)8.23147742
6sperm motility (GO:0030317)8.05507534
7fusion of sperm to egg plasma membrane (GO:0007342)7.87093214
8sperm-egg recognition (GO:0035036)6.82294186
9multicellular organism reproduction (GO:0032504)6.81325199
10acrosome reaction (GO:0007340)6.76609781
11cell wall macromolecule catabolic process (GO:0016998)6.74222291
12cell wall macromolecule metabolic process (GO:0044036)6.74222291
13intraciliary transport (GO:0042073)6.50873071
14protein insertion into membrane (GO:0051205)6.46106177
15protein polyglutamylation (GO:0018095)6.45654875
16acrosome assembly (GO:0001675)6.37655097
17single fertilization (GO:0007338)6.35629657
18binding of sperm to zona pellucida (GO:0007339)6.35602121
19microtubule severing (GO:0051013)6.32214264
20protein localization to cilium (GO:0061512)6.23107271
21cell-cell recognition (GO:0009988)6.18066660
22ventricular system development (GO:0021591)6.09567498
23GTP biosynthetic process (GO:0006183)6.08203893
24negative regulation of inclusion body assembly (GO:0090084)5.98144279
25nucleoside diphosphate phosphorylation (GO:0006165)5.95225761
26spermatid development (GO:0007286)5.92979153
27plasma membrane fusion (GO:0045026)5.90446644
28reproduction (GO:0000003)5.79706373
29primary alcohol catabolic process (GO:0034310)5.72514710
30regulation of microtubule-based movement (GO:0060632)5.67546606
31cilium morphogenesis (GO:0060271)5.63163474
32UTP biosynthetic process (GO:0006228)5.35863501
33fertilization (GO:0009566)5.26652490
34vitamin transmembrane transport (GO:0035461)5.21319967
35UTP metabolic process (GO:0046051)4.89979538
36ethanol metabolic process (GO:0006067)4.89750348
37cilium organization (GO:0044782)4.82530955
38regulation of female gonad development (GO:2000194)4.82255366
39diterpenoid biosynthetic process (GO:0016102)4.77583420
40cilium assembly (GO:0042384)4.72633017
41spermatid nucleus differentiation (GO:0007289)4.64331140
42regulation of inclusion body assembly (GO:0090083)4.59005274
43microtubule bundle formation (GO:0001578)4.56413538
44left/right axis specification (GO:0070986)4.55633335
45guanosine-containing compound biosynthetic process (GO:1901070)4.50013727
46brain morphogenesis (GO:0048854)4.45574090
47one-carbon compound transport (GO:0019755)4.45068796
48male meiosis (GO:0007140)4.40621288
49response to xenobiotic stimulus (GO:0009410)4.34963488
50tolerance induction (GO:0002507)4.33686616
51spermatogenesis (GO:0007283)4.32656245
52male gamete generation (GO:0048232)4.30377503
53microtubule polymerization or depolymerization (GO:0031109)4.22250295
54pyrimidine-containing compound transmembrane transport (GO:0072531)4.19854122
55sperm capacitation (GO:0048240)4.11220585
56piRNA metabolic process (GO:0034587)4.10743401
57CTP metabolic process (GO:0046036)4.04198633
58CTP biosynthetic process (GO:0006241)4.04198633
59cellular component assembly involved in morphogenesis (GO:0010927)4.02699137
60gamete generation (GO:0007276)4.02302055
61regulation of interleukin-13 production (GO:0032656)3.91543126
62regulation of interleukin-5 production (GO:0032674)3.84080114
63lung epithelium development (GO:0060428)3.83899677
64peptidyl-threonine dephosphorylation (GO:0035970)3.82174355
65glomerular epithelial cell development (GO:0072310)3.81968250
66microtubule-based movement (GO:0007018)3.78524833
67ethanol oxidation (GO:0006069)3.75977341
68negative regulation of T cell differentiation in thymus (GO:0033085)3.73125164
69calcium ion-dependent exocytosis (GO:0017156)3.72330542
70detection of calcium ion (GO:0005513)3.70245007
71synaptonemal complex organization (GO:0070193)3.65853506
72pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.64749363
73regulation of germinal center formation (GO:0002634)3.54665957
74negative regulation of B cell mediated immunity (GO:0002713)3.50555116
75negative regulation of immunoglobulin mediated immune response (GO:0002890)3.50555116
76establishment of apical/basal cell polarity (GO:0035089)3.50108259
77negative regulation of humoral immune response (GO:0002921)3.42875513
78cAMP biosynthetic process (GO:0006171)3.42607570
79pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.41031024
80lateral ventricle development (GO:0021670)3.36099982
81cytoplasmic microtubule organization (GO:0031122)3.35977437
82left/right pattern formation (GO:0060972)3.32011073
83positive regulation of tolerance induction (GO:0002645)3.31368091
84multicellular organismal reproductive process (GO:0048609)3.28020213
85cell recognition (GO:0008037)3.27958240
86regulation of protein kinase A signaling (GO:0010738)3.25063169
87determination of left/right symmetry (GO:0007368)3.22928486
88auditory receptor cell differentiation (GO:0042491)3.22427380
89retinoic acid metabolic process (GO:0042573)3.22414022
90nucleotide phosphorylation (GO:0046939)3.22123961
91adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.21749064
92negative regulation of cell killing (GO:0031342)3.21065309
93negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.21065309
94male meiosis I (GO:0007141)3.20009898
95germ cell development (GO:0007281)3.18880719
96cellular process involved in reproduction in multicellular organism (GO:0022412)3.17319933
97negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.16203566
98glycerol ether metabolic process (GO:0006662)3.14990354
99activation of protein kinase A activity (GO:0034199)3.14712405
100synaptonemal complex assembly (GO:0007130)3.14667803
101glutathione derivative metabolic process (GO:1901685)3.13960038
102glutathione derivative biosynthetic process (GO:1901687)3.13960038
103terpenoid biosynthetic process (GO:0016114)3.12411534
104innate immune response in mucosa (GO:0002227)3.12023700
105cell projection assembly (GO:0030031)3.10797054
106pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.10026133
107determination of bilateral symmetry (GO:0009855)3.08672215
108establishment of monopolar cell polarity (GO:0061162)3.07962024
109establishment or maintenance of monopolar cell polarity (GO:0061339)3.07962024
110peptidyl-glutamic acid modification (GO:0018200)3.04005374
111specification of symmetry (GO:0009799)3.02283606
112retinol metabolic process (GO:0042572)2.98638208
113regulation of chromatin binding (GO:0035561)2.98440824
114natural killer cell mediated cytotoxicity (GO:0042267)2.95552448
115natural killer cell mediated immunity (GO:0002228)2.95552448
116pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.93887959
117organic cation transport (GO:0015695)2.91333410
118ether metabolic process (GO:0018904)2.89607290
119microtubule-based process (GO:0007017)2.87450161
120retinal rod cell development (GO:0046548)2.85928082
121exogenous drug catabolic process (GO:0042738)2.84467150
122primary alcohol metabolic process (GO:0034308)2.82498630
123response to caffeine (GO:0031000)2.81439668
124establishment of tissue polarity (GO:0007164)2.80894220
125establishment of planar polarity (GO:0001736)2.80894220
126oligosaccharide catabolic process (GO:0009313)2.80608471
127smoothened signaling pathway (GO:0007224)2.80233285
128phosphorelay signal transduction system (GO:0000160)2.77648919
129organelle assembly (GO:0070925)2.77200760
130nucleoside diphosphate metabolic process (GO:0009132)2.77134916
131lipoxygenase pathway (GO:0019372)2.75876240
132antibacterial humoral response (GO:0019731)2.75188785
133centriole replication (GO:0007099)2.72385282
134cerebral cortex neuron differentiation (GO:0021895)2.71410853
135centriole assembly (GO:0098534)2.70733417
136lactate metabolic process (GO:0006089)2.70661734
137microtubule depolymerization (GO:0007019)2.69498575
138O-glycan processing (GO:0016266)2.66664724
139phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.58662265
140photoreceptor cell maintenance (GO:0045494)2.55185929
141retinal cone cell development (GO:0046549)2.51249627
142pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.51221360
143CDP-diacylglycerol biosynthetic process (GO:0016024)2.49996208
144glutathione metabolic process (GO:0006749)2.47165778
145hydrogen peroxide catabolic process (GO:0042744)2.46348664
146multicellular organismal water homeostasis (GO:0050891)2.46171057
147positive regulation of smoothened signaling pathway (GO:0045880)2.46116943
148excretion (GO:0007588)2.44166973
149hydrogen peroxide biosynthetic process (GO:0050665)2.43691017
150aldehyde catabolic process (GO:0046185)2.41882389
151regulation of autophagic vacuole assembly (GO:2000785)2.40563329
152carnitine metabolic process (GO:0009437)2.39954772
153regulation of tolerance induction (GO:0002643)2.39329173
154gas transport (GO:0015669)2.39073608
155phosphatidylcholine biosynthetic process (GO:0006656)2.37037198
156nonmotile primary cilium assembly (GO:0035058)2.35166972
157lateral sprouting from an epithelium (GO:0060601)2.34490889
158regulation of vacuole organization (GO:0044088)2.29889703
159heart looping (GO:0001947)2.28958748
160sensory perception of smell (GO:0007608)14.6011468
161axonemal dynein complex assembly (GO:0070286)12.0445857
162cilium movement (GO:0003341)11.4768703
163epithelial cilium movement (GO:0003351)10.7285125
164cilium or flagellum-dependent cell motility (GO:0001539)10.5717663

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.05391652
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.91887994
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.81113242
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.75565860
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.26803313
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.80348924
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.76709611
8FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.72922803
9GATA1_26923725_Chip-Seq_HPCs_Mouse2.47438008
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.11537134
11VDR_22108803_ChIP-Seq_LS180_Human2.08919459
12TAF15_26573619_Chip-Seq_HEK293_Human2.05342631
13POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.87168489
14TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.87168489
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.85424012
16RNF2_27304074_Chip-Seq_NSC_Mouse1.82954270
17ESR1_20079471_ChIP-ChIP_T-47D_Human1.82088415
18SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.76499688
19ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75769153
20FOXM1_26456572_ChIP-Seq_MCF-7_Human1.71389054
21GBX2_23144817_ChIP-Seq_PC3_Human1.70936664
22* PIAS1_25552417_ChIP-Seq_VCAP_Human1.70802289
23GATA1_19941826_ChIP-Seq_K562_Human1.69808055
24STAT1_20625510_ChIP-Seq_HELA_Human1.69330665
25MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.68780282
26DROSHA_22980978_ChIP-Seq_HELA_Human1.65268467
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.61916485
28KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.61698247
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59474077
30STAT6_21828071_ChIP-Seq_BEAS2B_Human1.56751995
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.56636195
32CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54454430
33TP63_23658742_ChIP-Seq_EP156T_Human1.53946850
34EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.52158749
35TAL1_26923725_Chip-Seq_HPCs_Mouse1.51774986
36FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.49318257
37ZNF217_24962896_ChIP-Seq_MCF-7_Human1.48947607
38KAP1_22055183_ChIP-Seq_ESCs_Mouse1.48791003
39SMRT_27268052_Chip-Seq_Bcells_Human1.47690719
40AHR_22903824_ChIP-Seq_MCF-7_Human1.45380693
41SMAD4_21799915_ChIP-Seq_A2780_Human1.43392409
42PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.42686578
43EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.41240777
44TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.40332508
45REST_21632747_ChIP-Seq_MESCs_Mouse1.40201329
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.38616358
47ETV1_20927104_ChIP-Seq_GIST48_Human1.37740638
48SMAD4_21741376_ChIP-Seq_EPCs_Human1.36521164
49GATA2_19941826_ChIP-Seq_K562_Human1.36085555
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35211026
51HNFA_21074721_ChIP-Seq_CACO-2_Human1.34821981
52P53_22387025_ChIP-Seq_ESCs_Mouse1.33835881
53PHF8_20622853_ChIP-Seq_HELA_Human1.33309394
54CTNNB1_20460455_ChIP-Seq_HCT116_Human1.33288373
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32741406
56GF1_26923725_Chip-Seq_HPCs_Mouse1.32682103
57CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.32202723
58NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31454703
59SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.31146411
60CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.31117738
61SOX2_22085726_ChIP-Seq_NPCs_Mouse1.29904110
62SOX2_27498859_Chip-Seq_STOMACH_Mouse1.29412521
63TDRD3_21172665_ChIP-Seq_MCF-7_Human1.28610770
64P300_19829295_ChIP-Seq_ESCs_Human1.27670639
65PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.27570187
66RBPJ_21746931_ChIP-Seq_IB4_Human1.26697835
67* ARNT_22903824_ChIP-Seq_MCF-7_Human1.26151553
68TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25885726
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25321685
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.25200109
71GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24767163
72AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.24560698
73ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.23862421
74TP53_18474530_ChIP-ChIP_U2OS_Human1.23043414
75ZNF263_19887448_ChIP-Seq_K562_Human1.22910062
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.21075523
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.20803753
78LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20758432
79NFYA_21822215_ChIP-Seq_K562_Human1.20757169
80ELK4_26923725_Chip-Seq_MESODERM_Mouse1.20259438
81TBL1_22424771_ChIP-Seq_293T_Human1.20224353
82EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.20052347
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.19216173
84SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.18957357
85CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.18636788
86* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18252052
87TP63_22573176_ChIP-Seq_HFKS_Human1.18194266
88CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17930561
89LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17716083
90NFYB_21822215_ChIP-Seq_K562_Human1.16805003
91CMYC_18555785_Chip-Seq_ESCs_Mouse1.16710956
92SOX9_24532713_ChIP-Seq_HFSC_Mouse1.15872019
93CBX2_22325352_ChIP-Seq_293T-Rex_Human1.15115564
94PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14863819
95GATA4_25053715_ChIP-Seq_YYC3_Human1.14506478
96TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14099708
97STAT1_17558387_ChIP-Seq_HELA_Human1.14028336
98CEBPB_22108803_ChIP-Seq_LS180_Human1.13742809
99STAT3_23295773_ChIP-Seq_U87_Human1.13716736
100SOX2_18555785_Chip-Seq_ESCs_Mouse1.13653323
101GATA3_21867929_ChIP-Seq_TH1_Mouse1.12974769
102BCAT_22108803_ChIP-Seq_LS180_Human1.12522804
103CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11369752
104SMC4_20622854_ChIP-Seq_HELA_Human1.11148721
105RUNX1_27514584_Chip-Seq_MCF-7_Human1.11042966
106SUZ12_27294783_Chip-Seq_ESCs_Mouse1.10523088
107AUTS2_25519132_ChIP-Seq_293T-REX_Human1.10128580
108RAD21_21589869_ChIP-Seq_MESCs_Mouse1.09990804
109SOX2_20726797_ChIP-Seq_SW620_Human1.09549763
110ELF1_20517297_ChIP-Seq_JURKAT_Human1.09420056
111SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09224741
112TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.08586474
113SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08331652
114* FOXA1_25552417_ChIP-Seq_VCAP_Human1.08119082
115TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08106152
116GATA6_21074721_ChIP-Seq_CACO-2_Human1.07481035
117ER_23166858_ChIP-Seq_MCF-7_Human1.05773474
118YY1_22570637_ChIP-Seq_MALME-3M_Human1.05175993
119GATA3_21867929_ChIP-Seq_CD8_Mouse1.05062433
120OCT4_18555785_Chip-Seq_ESCs_Mouse1.04961598
121* WDR5_24793694_ChIP-Seq_LNCAP_Human1.03761537
122KDM2B_26808549_Chip-Seq_REH_Human1.03599050
123E2F1_18555785_Chip-Seq_ESCs_Mouse1.03340136
124P53_21459846_ChIP-Seq_SAOS-2_Human1.03239424
125ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03069379
126CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02832440
127MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.01914413
128EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01884398
129* KLF5_25053715_ChIP-Seq_YYC3_Human1.00651457
130SMAD3_21741376_ChIP-Seq_ESCs_Human1.00384733
131GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.99680169
132POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99163532
133STAT3_18555785_Chip-Seq_ESCs_Mouse0.98586356
134AR_20517297_ChIP-Seq_VCAP_Human0.98550986
135FOXO3_23340844_ChIP-Seq_DLD1_Human0.97463019
136P63_26484246_Chip-Seq_KERATINOCYTES_Human0.96830929
137LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96646323
138CBP_20019798_ChIP-Seq_JUKART_Human0.96415005
139IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96415005
140NANOG_20526341_ChIP-Seq_ESCs_Human0.96222508
141RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.96218514
142* TCF4_22108803_ChIP-Seq_LS180_Human0.95934910
143ZFX_18555785_Chip-Seq_ESCs_Mouse0.95932034
144EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95871057
145PU1_27457419_Chip-Seq_LIVER_Mouse0.95704853
146TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.95381491
147ESR2_21235772_ChIP-Seq_MCF-7_Human0.95150141
148RUNX1_27457419_Chip-Seq_LIVER_Mouse0.95135376
149* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94920900
150* FOXA1_25329375_ChIP-Seq_VCAP_Human0.94920900
151FLI1_21867929_ChIP-Seq_TH2_Mouse0.92954923
152P300_27268052_Chip-Seq_Bcells_Human0.92909799
153FOXH1_21741376_ChIP-Seq_EPCs_Human0.92800184
154TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.92737226
155NMYC_18555785_Chip-Seq_ESCs_Mouse0.92572208
156SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92571081
157GF1B_26923725_Chip-Seq_HPCs_Mouse0.92534066
158ZNF274_21170338_ChIP-Seq_K562_Hela0.92397761
159* TCF4_23295773_ChIP-Seq_U87_Human0.92212196
160BMI1_23680149_ChIP-Seq_NPCS_Mouse0.91505535
161CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91391906
162GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.91303951
163P300_18555785_Chip-Seq_ESCs_Mouse0.91154888
164PRDM14_20953172_ChIP-Seq_ESCs_Human0.91003627
165AR_25329375_ChIP-Seq_VCAP_Human0.90978329
166PPAR_26484153_Chip-Seq_NCI-H1993_Human0.90977353
167CTCF_20526341_ChIP-Seq_ESCs_Human0.90621004
168STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90504782
169FUS_26573619_Chip-Seq_HEK293_Human0.89357053
170RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89284768
171ERG_20517297_ChIP-Seq_VCAP_Human0.89256774

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.53045518
2MP0009780_abnormal_chondrocyte_physiolo3.49507266
3MP0005464_abnormal_platelet_physiology3.18627865
4MP0003698_abnormal_male_reproductive3.15637418
5MP0004043_abnormal_pH_regulation3.12276232
6MP0000566_synostosis2.71303010
7MP0001929_abnormal_gametogenesis2.66148598
8MP0002653_abnormal_ependyma_morphology2.59493074
9MP0008789_abnormal_olfactory_epithelium2.49991377
10MP0002277_abnormal_respiratory_mucosa2.42655905
11MP0005083_abnormal_biliary_tract2.41593107
12MP0000383_abnormal_hair_follicle2.36334106
13MP0003136_yellow_coat_color2.32561740
14MP0005394_taste/olfaction_phenotype2.26032982
15MP0005499_abnormal_olfactory_system2.26032982
16MP0002160_abnormal_reproductive_system2.09165152
17MP0004019_abnormal_vitamin_homeostasis2.00467244
18MP0001984_abnormal_olfaction13.7774015
19MP0003656_abnormal_erythrocyte_physiolo1.96020872
20MP0002210_abnormal_sex_determination1.95121157
21MP0010678_abnormal_skin_adnexa1.89518740
22MP0000465_gastrointestinal_hemorrhage1.89272737
23MP0002161_abnormal_fertility/fecundity1.79885659
24MP0005623_abnormal_meninges_morphology1.73345813
25MP0002184_abnormal_innervation1.70843292
26MP0003806_abnormal_nucleotide_metabolis1.60401259
27MP0002928_abnormal_bile_duct1.57856413
28MP0001145_abnormal_male_reproductive1.52733780
29MP0006082_CNS_inflammation1.50357144
30MP0005377_hearing/vestibular/ear_phenot1.46370121
31MP0003878_abnormal_ear_physiology1.46370121
32MP0008877_abnormal_DNA_methylation1.43875289
33MP0000653_abnormal_sex_gland1.43642840
34MP0002168_other_aberrant_phenotype1.40529274
35MP0005248_abnormal_Harderian_gland1.38028586
36MP0001485_abnormal_pinna_reflex1.35248114
37MP0005395_other_phenotype1.33072242
38MP0005646_abnormal_pituitary_gland1.31627394
39MP0008004_abnormal_stomach_pH1.30675204
40MP0000372_irregular_coat_pigmentation1.29902373
41MP0005645_abnormal_hypothalamus_physiol1.28120762
42MP0003879_abnormal_hair_cell1.25969683
43MP0003718_maternal_effect1.21095621
44MP0005636_abnormal_mineral_homeostasis1.20891394
45MP0003880_abnormal_central_pattern1.18766468
46MP0010155_abnormal_intestine_physiology1.17091451
47MP0010030_abnormal_orbit_morphology1.16593673
48MP0002557_abnormal_social/conspecific_i1.14321664
49MP0008995_early_reproductive_senescence1.14111328
50MP0001486_abnormal_startle_reflex1.12617670
51MP0005084_abnormal_gallbladder_morpholo1.09443929
52MP0005165_increased_susceptibility_to1.09131247
53MP0005551_abnormal_eye_electrophysiolog1.08674007
54MP0002752_abnormal_somatic_nervous1.08342125
55MP0002638_abnormal_pupillary_reflex1.08067206
56MP0002822_catalepsy1.05729530
57MP0001879_abnormal_lymphatic_vessel1.03550175
58MP0001293_anophthalmia1.02138519
59MP0000678_abnormal_parathyroid_gland1.00934033
60MP0005389_reproductive_system_phenotype1.00195313
61MP0002735_abnormal_chemical_nociception0.99246387
62MP0009765_abnormal_xenobiotic_induced0.98374017
63MP0005253_abnormal_eye_physiology0.97964629
64MP0008872_abnormal_physiological_respon0.97538206
65MP0003646_muscle_fatigue0.95364610
66MP0002876_abnormal_thyroid_physiology0.93476222
67MP0003693_abnormal_embryo_hatching0.91014742
68MP0009046_muscle_twitch0.88617156
69MP0003252_abnormal_bile_duct0.87845400
70MP0003303_peritoneal_inflammation0.87358412
71MP0001542_abnormal_bone_strength0.86932788
72MP0001346_abnormal_lacrimal_gland0.86643015
73MP0002102_abnormal_ear_morphology0.86469993
74MP0004133_heterotaxia0.84319370
75MP0002734_abnormal_mechanical_nocicepti0.83935688
76MP0002938_white_spotting0.83221038
77MP0008875_abnormal_xenobiotic_pharmacok0.82905171
78MP0002272_abnormal_nervous_system0.82210777
79MP0009643_abnormal_urine_homeostasis0.78160584
80MP0009763_increased_sensitivity_to0.78092700
81MP0005365_abnormal_bile_salt0.77870430
82MP0005085_abnormal_gallbladder_physiolo0.77792587
83MP0001970_abnormal_pain_threshold0.77369975
84MP0002882_abnormal_neuron_morphology0.77139615
85MP0005164_abnormal_response_to0.76843109
86MP0002295_abnormal_pulmonary_circulatio0.76146475
87MP0006036_abnormal_mitochondrial_physio0.75920606
88MP0002152_abnormal_brain_morphology0.75030616
89MP0005408_hypopigmentation0.74743287
90MP0001765_abnormal_ion_homeostasis0.74516832
91MP0005220_abnormal_exocrine_pancreas0.74363658
92MP0003634_abnormal_glial_cell0.73383435
93MP0004883_abnormal_blood_vessel0.73359013
94MP0002136_abnormal_kidney_physiology0.73151387
95MP0002092_abnormal_eye_morphology0.71413723
96MP0002249_abnormal_larynx_morphology0.70764626
97MP0002909_abnormal_adrenal_gland0.70666204
98MP0000778_abnormal_nervous_system0.70520515
99MP0004811_abnormal_neuron_physiology0.68302608
100MP0001663_abnormal_digestive_system0.66911218
101MP0005367_renal/urinary_system_phenotyp0.66695101
102MP0000516_abnormal_urinary_system0.66695101
103MP0003635_abnormal_synaptic_transmissio0.66140151
104MP0001270_distended_abdomen0.65794617
105MP0005187_abnormal_penis_morphology0.63999876
106MP0005310_abnormal_salivary_gland0.63474510
107MP0004215_abnormal_myocardial_fiber0.61708795
108MP0000681_abnormal_thyroid_gland0.61230466
109MP0002233_abnormal_nose_morphology0.60790488
110MP0002282_abnormal_trachea_morphology0.60463415
111MP0009379_abnormal_foot_pigmentation0.60169860
112MP0002063_abnormal_learning/memory/cond0.58622437
113MP0000343_altered_response_to0.58510669
114MP0003638_abnormal_response/metabolism_0.58102530
115MP0001851_eye_inflammation0.57699538
116MP0005195_abnormal_posterior_eye0.56196730
117MP0006054_spinal_hemorrhage0.56122027
118MP0000230_abnormal_systemic_arterial0.55911853
119MP0003942_abnormal_urinary_system0.55911574
120MP0004085_abnormal_heartbeat0.55875114
121MP0001849_ear_inflammation0.54745415
122MP0010329_abnormal_lipoprotein_level0.54503544
123MP0000249_abnormal_blood_vessel0.53279313
124MP0002572_abnormal_emotion/affect_behav0.52814827
125MP0004742_abnormal_vestibular_system0.51386791
126MP0003866_abnormal_defecation0.50633016
127MP0003861_abnormal_nervous_system0.50509075
128MP0002132_abnormal_respiratory_system0.49989949
129MP0004145_abnormal_muscle_electrophysio0.49823783
130MP0005423_abnormal_somatic_nervous0.49498029
131MP0001756_abnormal_urination0.49485313
132MP0004084_abnormal_cardiac_muscle0.48003946
133MP0005409_darkened_coat_color0.47794569
134MP0002877_abnormal_melanocyte_morpholog0.47260461
135MP0003943_abnormal_hepatobiliary_system0.47109225
136MP0001666_abnormal_nutrient_absorption0.46622088
137MP0005670_abnormal_white_adipose0.46182287
138MP0002229_neurodegeneration0.46154710
139MP0005391_vision/eye_phenotype0.45439860
140MP0004858_abnormal_nervous_system0.45295665
141MP0003828_pulmonary_edema0.45179049
142MP0001324_abnormal_eye_pigmentation0.44916188
143MP0003453_abnormal_keratinocyte_physiol0.44582699
144MP0002064_seizures0.43912060
145MP0005584_abnormal_enzyme/coenzyme_acti0.43790280
146MP0002405_respiratory_system_inflammati0.43576423
147MP0001119_abnormal_female_reproductive0.43388081
148MP0003633_abnormal_nervous_system0.38649607
149MP0001501_abnormal_sleep_pattern0.38570353
150MP0003075_altered_response_to0.36999768
151MP0003699_abnormal_female_reproductive0.36753401
152MP0005647_abnormal_sex_gland0.36395178
153MP0000026_abnormal_inner_ear0.36190937
154MP0000049_abnormal_middle_ear0.35530507
155MP0001963_abnormal_hearing_physiology0.34214156
156MP0003941_abnormal_skin_development0.33835766
157MP0005174_abnormal_tail_pigmentation0.32062067
158MP0001664_abnormal_digestion0.31901128
159MP0000534_abnormal_ureter_morphology0.31375020
160MP0000538_abnormal_urinary_bladder0.30881037
161MP0001299_abnormal_eye_distance/0.30583586
162MP0005166_decreased_susceptibility_to0.30481731

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)8.98603371
2Dynein arm defect of respiratory motile cilia (HP:0012255)8.92014776
3Absent/shortened dynein arms (HP:0200106)8.92014776
4Abnormal respiratory epithelium morphology (HP:0012253)8.66681937
5Abnormal respiratory motile cilium morphology (HP:0005938)8.66681937
6Rhinitis (HP:0012384)8.30696398
7Chronic bronchitis (HP:0004469)7.15090466
8Nasal polyposis (HP:0100582)5.33489358
9Retinal dysplasia (HP:0007973)5.17435405
10Bronchiectasis (HP:0002110)5.05224521
11Molar tooth sign on MRI (HP:0002419)4.71326282
12Abnormality of midbrain morphology (HP:0002418)4.71326282
13Abnormality of the nasal mucosa (HP:0000433)4.36861978
14Bifid tongue (HP:0010297)4.35772744
15Infertility (HP:0000789)3.91478221
16Pancreatic fibrosis (HP:0100732)3.68114001
17Bronchitis (HP:0012387)3.67789297
18True hermaphroditism (HP:0010459)3.59385419
19Medial flaring of the eyebrow (HP:0010747)3.54111929
20Nephronophthisis (HP:0000090)3.46059723
21Supernumerary spleens (HP:0009799)3.24397416
22Recurrent sinusitis (HP:0011108)3.20092365
23Male infertility (HP:0003251)3.13081911
24Gait imbalance (HP:0002141)3.12749820
25Congenital primary aphakia (HP:0007707)3.10298156
26Chronic hepatic failure (HP:0100626)3.06541096
27Occipital encephalocele (HP:0002085)3.02238424
28Bile duct proliferation (HP:0001408)2.96943113
29Abnormal biliary tract physiology (HP:0012439)2.96943113
30Nephrogenic diabetes insipidus (HP:0009806)2.94716394
31Chronic otitis media (HP:0000389)2.94512952
32Abnormality of macular pigmentation (HP:0008002)2.94413210
33Recurrent otitis media (HP:0000403)2.78906746
34Tubulointerstitial nephritis (HP:0001970)2.78007542
35Central scotoma (HP:0000603)2.76776266
36Abolished electroretinogram (ERG) (HP:0000550)2.76699029
37Hyperactive renin-angiotensin system (HP:0000841)2.74606901
38Postaxial hand polydactyly (HP:0001162)2.73569071
39Genital tract atresia (HP:0001827)2.66242784
40Pancreatic cysts (HP:0001737)2.60813814
41Vaginal atresia (HP:0000148)2.59425993
42Abnormality of the renal medulla (HP:0100957)2.59287354
43Cystic liver disease (HP:0006706)2.59052107
44Oculomotor apraxia (HP:0000657)2.56640537
45Chronic sinusitis (HP:0011109)2.52076903
46Abnormality of dentin (HP:0010299)2.50876124
47Bony spicule pigmentary retinopathy (HP:0007737)2.49792401
48Limb dystonia (HP:0002451)2.46813149
49Congenital hepatic fibrosis (HP:0002612)2.37429754
50Postaxial foot polydactyly (HP:0001830)2.35753454
51Median cleft lip (HP:0000161)2.34635810
52Constricted visual fields (HP:0001133)2.31989997
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.23280504
54Poor coordination (HP:0002370)2.22859249
55Aplasia/Hypoplasia of the lens (HP:0008063)2.19925351
56Facial cleft (HP:0002006)2.16512568
57Abnormality of the dental root (HP:0006486)2.13846959
58Taurodontia (HP:0000679)2.13846959
59Abnormality of permanent molar morphology (HP:0011071)2.13846959
60Dyschromatopsia (HP:0007641)2.13202145
61Short nail (HP:0001799)2.06094502
62Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.3911863
63Abnormal respiratory motile cilium physiology (HP:0012261)10.2424308
64Abnormality of molar morphology (HP:0011070)1.99162250
65Abnormality of molar (HP:0011077)1.99162250
66Bell-shaped thorax (HP:0001591)1.97995505
67Tubular atrophy (HP:0000092)1.94766094
68Abnormality of the dental pulp (HP:0006479)1.90561609
69Dysphonia (HP:0001618)1.85517268
70Palpitations (HP:0001962)1.84335403
71Syncope (HP:0001279)1.84298139
72Stage 5 chronic kidney disease (HP:0003774)1.74907402
73Termporal pattern (HP:0011008)1.70962595
74Insidious onset (HP:0003587)1.70962595
75Male pseudohermaphroditism (HP:0000037)1.70540881
76Decreased circulating renin level (HP:0003351)1.68807853
77Furrowed tongue (HP:0000221)1.68501788
78Purpura (HP:0000979)1.66414223
79Tubulointerstitial abnormality (HP:0001969)1.66285306
80Renal salt wasting (HP:0000127)1.65684216
81Renal hypoplasia (HP:0000089)1.65095879
82Sclerocornea (HP:0000647)1.63305933
83Narrow forehead (HP:0000341)1.61850800
84Retinitis pigmentosa (HP:0000510)1.58437181
85Decreased central vision (HP:0007663)1.58408414
86Anencephaly (HP:0002323)1.57731346
87Prolonged bleeding time (HP:0003010)1.53973093
88Hyperkalemia (HP:0002153)1.52514031
89Atonic seizures (HP:0010819)1.51998360
90Absent frontal sinuses (HP:0002688)1.51522569
91Asplenia (HP:0001746)1.50936919
92Aplasia/Hypoplasia of the spleen (HP:0010451)1.47799928
93Absent eyebrow (HP:0002223)1.46787732
94Cone-rod dystrophy (HP:0000548)1.46373794
95Preaxial hand polydactyly (HP:0001177)1.45906230
96Hyperaldosteronism (HP:0000859)1.44317799
97Absent rod-and cone-mediated responses on ERG (HP:0007688)1.43678529
98Aganglionic megacolon (HP:0002251)1.42402353
99Vacuolated lymphocytes (HP:0001922)1.39166471
100Torticollis (HP:0000473)1.38570589
101Specific learning disability (HP:0001328)1.37141379
102Scotoma (HP:0000575)1.37003242
103Recurrent bronchitis (HP:0002837)1.36255183
104Omphalocele (HP:0001539)1.35614367
105Polydipsia (HP:0001959)1.35228526
106Abnormal drinking behavior (HP:0030082)1.35228526
107Anosmia (HP:0000458)1.33931786
108Menorrhagia (HP:0000132)1.33199655
109Ventricular fibrillation (HP:0001663)1.28742396
110Abnormality of renin-angiotensin system (HP:0000847)1.27113043
111Short thorax (HP:0010306)1.26836987
112Prominent nasal bridge (HP:0000426)1.26021668
113Abnormality of chloride homeostasis (HP:0011422)1.25043172
114Nephropathy (HP:0000112)1.23979531
115Hypodontia (HP:0000668)1.23948294
116Hypokalemic alkalosis (HP:0001949)1.23825282
117Atelectasis (HP:0100750)1.23739471
118Abnormal spermatogenesis (HP:0008669)1.22825690
119Fibular hypoplasia (HP:0003038)1.22326767
120Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.20107473
121Abnormal rod and cone electroretinograms (HP:0008323)1.18746034
122Abnormality of the renal cortex (HP:0011035)1.18513344
123Hyponatremia (HP:0002902)1.12853024
124Petechiae (HP:0000967)1.07262115
125Tubulointerstitial fibrosis (HP:0005576)1.05889086
126Increased mean platelet volume (HP:0011877)1.03464681
127Glucose intolerance (HP:0000833)1.01519398
128Portal hypertension (HP:0001409)0.99889361
129Abnormality of the frontal sinuses (HP:0002687)0.98454512

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.19634880
2PDK35.11456052
3PDK45.11456052
4PRKD33.63890248
5PNCK3.42911214
6EPHA23.23239445
7PDK23.14354717
8TESK13.11050155
9ICK3.08154987
10EEF2K2.62583263
11STK242.14466448
12RIPK42.10501275
13PHKG22.05873227
14PHKG12.05873227
15ERBB32.05179699
16PAK31.97035331
17STK391.89933077
18MAP3K21.72209044
19MAPKAPK31.68924189
20CAMK2B1.63730414
21CAMK2D1.60102283
22PTK2B1.48958149
23NME11.43867778
24MYLK1.42894613
25MAP2K21.36233124
26CAMK2G1.33182596
27WNK41.31504781
28BCR1.29861019
29CSNK1G11.27790221
30MUSK1.26722720
31MAP3K31.26184386
32CAMKK21.25551023
33MAPKAPK51.25341736
34MAP3K121.24069643
35STK381.23053953
36DYRK31.22465605
37CAMK1G1.20214051
38CSNK1A1L1.14903175
39TLK11.12288302
40BMX1.11619432
41DAPK21.10605230
42NLK1.08264323
43NEK61.07073552
44CSNK1G31.04502173
45LRRK21.03486294
46PRKCG1.03087400
47STK38L0.99926977
48EPHA30.96530131
49DYRK1B0.94273073
50BRSK20.93680233
51MARK20.90788803
52ERBB20.90716635
53CAMKK10.89546904
54CDK30.88868560
55NUAK10.87459954
56TEC0.85981866
57CSNK1G20.84585760
58FRK0.80821817
59IRAK10.80239533
60MST40.78940410
61RPS6KA20.78616061
62GRK60.78615242
63DYRK1A0.73597978
64BTK0.72338287
65FER0.72179083
66MAP3K70.69977624
67EPHB10.69299768
68STK160.68754128
69PLK40.68476817
70CAMK2A0.67274966
71PRKCI0.67164211
72EIF2AK10.66987166
73GRK10.62717257
74LATS10.62396719
75INSRR0.62107011
76MAP4K20.60772838
77PLK20.60331827
78MAP3K40.60215141
79WNK10.59660316
80STK100.59462479
81MST1R0.56721980
82SRPK10.56210165
83TRIB30.55660028
84STK30.55422759
85PDK10.55172887
86TYRO30.54572671
87ACVR1B0.54335018
88ZAP700.52190531
89ITK0.52141926
90TRPM70.51564475
91PRKAA20.49801792
92AURKA0.49686728
93STK110.48162251
94CSK0.48038754
95SMG10.47481219
96ROCK10.46716599
97NEK20.44516347
98PIK3CG0.42482339
99ADRBK20.42190952
100PRKCD0.41991409
101PIM20.41059557
102NTRK20.40446931
103SGK2230.39358072
104SGK4940.39358072
105MAPK70.38077544
106ARAF0.37198493
107PRKG10.36814314
108PRKCZ0.36804858
109ADRBK10.35866968
110LMTK20.35778744
111CAMK1D0.35480586
112HIPK20.34999641
113CDK120.34613812
114TBK10.33977346
115PKN10.33423615
116RIPK10.33081462
117CDK90.32712541
118TTK0.32527186
119TAOK10.32455970
120GSK3A0.31601357
121PRKCQ0.31077429
122PRKD20.30901467
123RET0.30820260
124PRKCA0.29183463
125MAPK130.28437579
126SGK10.27816361
127PRKAA10.26400875
128ROCK20.26319733
129SGK20.26231846
130BMPR1B0.25583767
131MET0.25097979
132CCNB10.24974320
133PDPK10.24582326
134PRKACA0.24478361
135MAP2K10.24204919
136MAPKAPK20.23881949
137FYN0.23790273
138EGFR0.23588764
139PAK10.23265114
140AKT30.23251984
141PRKACG0.22657421
142MAP3K50.22430296
143CHEK20.22422834
144CSNK1D0.22130979
145MAP2K70.22029818
146CDC70.22014338
147CSF1R0.21848322
148BRAF0.21315790
149GRK50.19774325
150ILK0.19531544
151MARK10.18857782
152CAMK10.18855714
153DAPK10.18711404
154PINK10.17867787
155BMPR20.16360781
156MAPK100.15821793
157INSR0.15517212

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003603.95302577
2Tyrosine metabolism_Homo sapiens_hsa003503.38357566
3Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.77756369
4Phototransduction_Homo sapiens_hsa047442.27771308
5Fatty acid biosynthesis_Homo sapiens_hsa000612.19603296
6Olfactory transduction_Homo sapiens_hsa0474010.6587718
7Insulin secretion_Homo sapiens_hsa049111.88550587
8Caffeine metabolism_Homo sapiens_hsa002321.87637969
9Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.85027937
10Ovarian steroidogenesis_Homo sapiens_hsa049131.81530215
11Taste transduction_Homo sapiens_hsa047421.75370940
12Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.75214532
13Propanoate metabolism_Homo sapiens_hsa006401.71957495
14Gastric acid secretion_Homo sapiens_hsa049711.67126400
15cAMP signaling pathway_Homo sapiens_hsa040241.61792322
16Steroid hormone biosynthesis_Homo sapiens_hsa001401.56738123
17Pyruvate metabolism_Homo sapiens_hsa006201.54173872
18Bile secretion_Homo sapiens_hsa049761.52017446
19Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.49110521
20Sphingolipid metabolism_Homo sapiens_hsa006001.45565281
21Salivary secretion_Homo sapiens_hsa049701.44200807
22Other glycan degradation_Homo sapiens_hsa005111.43357296
23Glucagon signaling pathway_Homo sapiens_hsa049221.42707631
24Circadian entrainment_Homo sapiens_hsa047131.40621705
25Morphine addiction_Homo sapiens_hsa050321.36681620
26Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.33435329
27Histidine metabolism_Homo sapiens_hsa003401.31169236
28Collecting duct acid secretion_Homo sapiens_hsa049661.30189028
29Thyroid hormone synthesis_Homo sapiens_hsa049181.29556948
30cGMP-PKG signaling pathway_Homo sapiens_hsa040221.27962260
31Amphetamine addiction_Homo sapiens_hsa050311.27406276
32Purine metabolism_Homo sapiens_hsa002301.26257448
33Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.25879439
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.24266057
35Tight junction_Homo sapiens_hsa045301.21651038
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.20805770
37Nitrogen metabolism_Homo sapiens_hsa009101.20453128
38Huntingtons disease_Homo sapiens_hsa050161.18495231
39Platelet activation_Homo sapiens_hsa046111.15009261
40Glutamatergic synapse_Homo sapiens_hsa047241.13648330
41Estrogen signaling pathway_Homo sapiens_hsa049151.07638242
42Calcium signaling pathway_Homo sapiens_hsa040201.06388594
43Peroxisome_Homo sapiens_hsa041461.01590527
44Renin secretion_Homo sapiens_hsa049241.01204499
45Oocyte meiosis_Homo sapiens_hsa041140.99953025
46SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99801530
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.98696682
48Circadian rhythm_Homo sapiens_hsa047100.98008494
49Hematopoietic cell lineage_Homo sapiens_hsa046400.96189737
50Carbohydrate digestion and absorption_Homo sapiens_hsa049730.95963333
51Serotonergic synapse_Homo sapiens_hsa047260.94728806
52Vitamin B6 metabolism_Homo sapiens_hsa007500.92669178
53Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91378275
54Dopaminergic synapse_Homo sapiens_hsa047280.90918090
55PPAR signaling pathway_Homo sapiens_hsa033200.88784752
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.87231802
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.86339404
58Starch and sucrose metabolism_Homo sapiens_hsa005000.86029813
59Arachidonic acid metabolism_Homo sapiens_hsa005900.83929733
60Pancreatic secretion_Homo sapiens_hsa049720.79722258
61Vibrio cholerae infection_Homo sapiens_hsa051100.79718563
62GABAergic synapse_Homo sapiens_hsa047270.79008050
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75765063
64Leukocyte transendothelial migration_Homo sapiens_hsa046700.75679787
65Linoleic acid metabolism_Homo sapiens_hsa005910.74986102
66Cardiac muscle contraction_Homo sapiens_hsa042600.73677031
67Cholinergic synapse_Homo sapiens_hsa047250.72699338
68Alcoholism_Homo sapiens_hsa050340.72276335
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72230404
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.72031188
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70752662
72Mineral absorption_Homo sapiens_hsa049780.70552719
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69165672
74Notch signaling pathway_Homo sapiens_hsa043300.69009926
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68059728
76Systemic lupus erythematosus_Homo sapiens_hsa053220.67404213
77Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.66925339
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.66701563
79GnRH signaling pathway_Homo sapiens_hsa049120.66455635
80ABC transporters_Homo sapiens_hsa020100.65616848
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64895601
82Choline metabolism in cancer_Homo sapiens_hsa052310.62145984
83Basal transcription factors_Homo sapiens_hsa030220.62140149
84ECM-receptor interaction_Homo sapiens_hsa045120.61609268
85Dorso-ventral axis formation_Homo sapiens_hsa043200.59326436
86Oxytocin signaling pathway_Homo sapiens_hsa049210.56832365
87Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55141385
88Long-term potentiation_Homo sapiens_hsa047200.54603683
89Gap junction_Homo sapiens_hsa045400.53611086
90Adherens junction_Homo sapiens_hsa045200.52419578
91Melanogenesis_Homo sapiens_hsa049160.51772247
92Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.48635751
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.48537957
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48414885
95Nicotine addiction_Homo sapiens_hsa050330.45251004
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44832594
97Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44628752
98Ether lipid metabolism_Homo sapiens_hsa005650.44301213
99Arginine and proline metabolism_Homo sapiens_hsa003300.42520264
100Endocytosis_Homo sapiens_hsa041440.42140352
101Chemical carcinogenesis_Homo sapiens_hsa052040.38817462
102Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36860478
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36515805
104Complement and coagulation cascades_Homo sapiens_hsa046100.35327413
105Dilated cardiomyopathy_Homo sapiens_hsa054140.34996996
106Fatty acid degradation_Homo sapiens_hsa000710.34617023
107Parkinsons disease_Homo sapiens_hsa050120.34366852
108Regulation of autophagy_Homo sapiens_hsa041400.34193742
109Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34025278
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.33983923
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33361780
112Sulfur relay system_Homo sapiens_hsa041220.33338828
113Hedgehog signaling pathway_Homo sapiens_hsa043400.32551635
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.32175453
115Alzheimers disease_Homo sapiens_hsa050100.30666449
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.30380948
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30113646
118Cocaine addiction_Homo sapiens_hsa050300.30083508
119Amoebiasis_Homo sapiens_hsa051460.29937858
120Metabolic pathways_Homo sapiens_hsa011000.29814809
121Phagosome_Homo sapiens_hsa041450.29562061
122Synaptic vesicle cycle_Homo sapiens_hsa047210.29107824
123beta-Alanine metabolism_Homo sapiens_hsa004100.28681721
124Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.28241966
125Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27922344
126Glycerolipid metabolism_Homo sapiens_hsa005610.26773536
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.25870583
128Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.25675922
129Hepatitis C_Homo sapiens_hsa051600.23449531
130Retinol metabolism_Homo sapiens_hsa008300.22974647
131Carbon metabolism_Homo sapiens_hsa012000.22704843
132AMPK signaling pathway_Homo sapiens_hsa041520.21688960
133Primary bile acid biosynthesis_Homo sapiens_hsa001200.21611561
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21092947
135Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20986109
136Butanoate metabolism_Homo sapiens_hsa006500.20190916
137Non-homologous end-joining_Homo sapiens_hsa034500.20106326
138Inositol phosphate metabolism_Homo sapiens_hsa005620.20059915
139Chemokine signaling pathway_Homo sapiens_hsa040620.19823648
140Rap1 signaling pathway_Homo sapiens_hsa040150.18586058
141Pentose phosphate pathway_Homo sapiens_hsa000300.16416760
142Glutathione metabolism_Homo sapiens_hsa004800.15728743
143Jak-STAT signaling pathway_Homo sapiens_hsa046300.15639288

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