Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.07737162 |
2 | DNA double-strand break processing (GO:0000729) | 5.04110324 |
3 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.67984017 |
4 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.66689305 |
5 | synapsis (GO:0007129) | 4.55325834 |
6 | DNA strand elongation (GO:0022616) | 4.44788345 |
7 | formation of translation preinitiation complex (GO:0001731) | 4.27158512 |
8 | telomere maintenance via recombination (GO:0000722) | 4.27041409 |
9 | DNA replication initiation (GO:0006270) | 4.25132415 |
10 | tRNA methylation (GO:0030488) | 4.22283684 |
11 | DNA replication checkpoint (GO:0000076) | 4.21570514 |
12 | maturation of SSU-rRNA (GO:0030490) | 4.06504629 |
13 | DNA ligation (GO:0006266) | 4.04446419 |
14 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.03875481 |
15 | mitotic recombination (GO:0006312) | 3.95251095 |
16 | CENP-A containing nucleosome assembly (GO:0034080) | 3.94939013 |
17 | replication fork processing (GO:0031297) | 3.91857044 |
18 | DNA deamination (GO:0045006) | 3.86990800 |
19 | chromatin remodeling at centromere (GO:0031055) | 3.85681409 |
20 | spliceosomal snRNP assembly (GO:0000387) | 3.83072571 |
21 | mitotic metaphase plate congression (GO:0007080) | 3.81361480 |
22 | proteasome assembly (GO:0043248) | 3.80521646 |
23 | viral transcription (GO:0019083) | 3.78139494 |
24 | ribosomal small subunit biogenesis (GO:0042274) | 3.77491955 |
25 | nucleobase biosynthetic process (GO:0046112) | 3.75852004 |
26 | telomere maintenance via telomere lengthening (GO:0010833) | 3.74452141 |
27 | translational termination (GO:0006415) | 3.74347682 |
28 | regulation of DNA endoreduplication (GO:0032875) | 3.70046886 |
29 | kinetochore organization (GO:0051383) | 3.57802726 |
30 | resolution of meiotic recombination intermediates (GO:0000712) | 3.57411464 |
31 | purine nucleobase biosynthetic process (GO:0009113) | 3.49259148 |
32 | IMP metabolic process (GO:0046040) | 3.48793032 |
33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.47718976 |
34 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.46820119 |
35 | ribosomal large subunit biogenesis (GO:0042273) | 3.46475637 |
36 | DNA unwinding involved in DNA replication (GO:0006268) | 3.44245718 |
37 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.43254937 |
38 | DNA replication-independent nucleosome organization (GO:0034724) | 3.42984563 |
39 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.42984563 |
40 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.42972672 |
41 | cotranslational protein targeting to membrane (GO:0006613) | 3.39955357 |
42 | translational elongation (GO:0006414) | 3.39611502 |
43 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.38189681 |
44 | protein targeting to ER (GO:0045047) | 3.36099852 |
45 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.35957078 |
46 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.35957078 |
47 | metaphase plate congression (GO:0051310) | 3.34980637 |
48 | centriole replication (GO:0007099) | 3.34788925 |
49 | spindle checkpoint (GO:0031577) | 3.34029122 |
50 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.33322233 |
51 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.32329216 |
52 | regulation of centriole replication (GO:0046599) | 3.31911318 |
53 | histone H2A acetylation (GO:0043968) | 3.31860482 |
54 | ribosome biogenesis (GO:0042254) | 3.31191810 |
55 | mitotic sister chromatid cohesion (GO:0007064) | 3.29639256 |
56 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.28897469 |
57 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.27880400 |
58 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.27880400 |
59 | negative regulation of sister chromatid segregation (GO:0033046) | 3.27880400 |
60 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.27880400 |
61 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.27880400 |
62 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.27341162 |
63 | sister chromatid segregation (GO:0000819) | 3.27186293 |
64 | protein localization to endoplasmic reticulum (GO:0070972) | 3.26595189 |
65 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.25777671 |
66 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.25543134 |
67 | translational initiation (GO:0006413) | 3.25216326 |
68 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.24852523 |
69 | mitotic spindle checkpoint (GO:0071174) | 3.24787621 |
70 | kinetochore assembly (GO:0051382) | 3.23917141 |
71 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.23344529 |
72 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.23344529 |
73 | negative regulation of DNA recombination (GO:0045910) | 3.23054278 |
74 | negative regulation of chromosome segregation (GO:0051985) | 3.21938924 |
75 | mitotic sister chromatid segregation (GO:0000070) | 3.21703223 |
76 | IMP biosynthetic process (GO:0006188) | 3.21663570 |
77 | rRNA processing (GO:0006364) | 3.20909198 |
78 | non-recombinational repair (GO:0000726) | 3.19635589 |
79 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.19635589 |
80 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.19255446 |
81 | postreplication repair (GO:0006301) | 3.19189785 |
82 | mitotic G2/M transition checkpoint (GO:0044818) | 3.18999216 |
83 | protein localization to kinetochore (GO:0034501) | 3.18591384 |
84 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.18540868 |
85 | histone exchange (GO:0043486) | 3.18438612 |
86 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.16916745 |
87 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.15323395 |
88 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.13479668 |
89 | rRNA metabolic process (GO:0016072) | 3.13393647 |
90 | DNA damage response, detection of DNA damage (GO:0042769) | 3.12521273 |
91 | establishment of chromosome localization (GO:0051303) | 3.12251022 |
92 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.12086819 |
93 | termination of RNA polymerase III transcription (GO:0006386) | 3.12086819 |
94 | viral mRNA export from host cell nucleus (GO:0046784) | 3.09912522 |
95 | mitotic spindle assembly checkpoint (GO:0007094) | 3.09581229 |
96 | recombinational repair (GO:0000725) | 3.08163961 |
97 | spindle assembly checkpoint (GO:0071173) | 3.07095354 |
98 | translation (GO:0006412) | 3.06566839 |
99 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.06047444 |
100 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.06047444 |
101 | double-strand break repair via homologous recombination (GO:0000724) | 3.05713402 |
102 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.05584776 |
103 | mitotic nuclear envelope disassembly (GO:0007077) | 3.04923207 |
104 | rRNA modification (GO:0000154) | 3.04229581 |
105 | transcription from RNA polymerase I promoter (GO:0006360) | 3.02262090 |
106 | histone-serine phosphorylation (GO:0035404) | 3.02128736 |
107 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.01305569 |
108 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.00552186 |
109 | respiratory chain complex IV assembly (GO:0008535) | 3.00162029 |
110 | cellular protein complex disassembly (GO:0043624) | 2.99118717 |
111 | protein localization to chromosome, centromeric region (GO:0071459) | 2.98537647 |
112 | cell cycle G1/S phase transition (GO:0044843) | 2.98214597 |
113 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.98214597 |
114 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.98043897 |
115 | negative regulation of ligase activity (GO:0051352) | 2.98043897 |
116 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.97213499 |
117 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.97213499 |
118 | regulation of sister chromatid segregation (GO:0033045) | 2.97213499 |
119 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.96334638 |
120 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.96233823 |
121 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.96233823 |
122 | regulation of helicase activity (GO:0051095) | 2.96125418 |
123 | reciprocal meiotic recombination (GO:0007131) | 2.95965511 |
124 | reciprocal DNA recombination (GO:0035825) | 2.95965511 |
125 | 7-methylguanosine mRNA capping (GO:0006370) | 2.95379837 |
126 | meiotic chromosome segregation (GO:0045132) | 2.94637671 |
127 | 7-methylguanosine RNA capping (GO:0009452) | 2.93511194 |
128 | RNA capping (GO:0036260) | 2.93511194 |
129 | pseudouridine synthesis (GO:0001522) | 2.93461698 |
130 | histone mRNA metabolic process (GO:0008334) | 2.92906789 |
131 | intra-S DNA damage checkpoint (GO:0031573) | 2.92454542 |
132 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.92419372 |
133 | cullin deneddylation (GO:0010388) | 2.92218038 |
134 | establishment of integrated proviral latency (GO:0075713) | 2.91818224 |
135 | viral life cycle (GO:0019058) | 2.90760196 |
136 | spliceosomal complex assembly (GO:0000245) | 2.90276184 |
137 | telomere organization (GO:0032200) | 2.90262091 |
138 | telomere maintenance (GO:0000723) | 2.90081877 |
139 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.87908019 |
140 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.87908019 |
141 | protein K6-linked ubiquitination (GO:0085020) | 2.86731564 |
142 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.86708203 |
143 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.86708203 |
144 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.86708203 |
145 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.86611737 |
146 | ATP-dependent chromatin remodeling (GO:0043044) | 2.86596065 |
147 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.85183801 |
148 | N-terminal protein amino acid acetylation (GO:0006474) | 2.85092005 |
149 | maturation of 5.8S rRNA (GO:0000460) | 2.83894549 |
150 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.83492186 |
151 | chromosome organization involved in meiosis (GO:0070192) | 2.80813551 |
152 | termination of RNA polymerase I transcription (GO:0006363) | 2.80493090 |
153 | cellular component biogenesis (GO:0044085) | 2.80390020 |
154 | DNA topological change (GO:0006265) | 2.79362427 |
155 | regulation of chromosome segregation (GO:0051983) | 2.78377982 |
156 | protein deneddylation (GO:0000338) | 2.76961232 |
157 | translesion synthesis (GO:0019985) | 2.75685497 |
158 | regulation of mitochondrial translation (GO:0070129) | 2.75222021 |
159 | cytochrome complex assembly (GO:0017004) | 2.75050678 |
160 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.74585358 |
161 | ATP synthesis coupled proton transport (GO:0015986) | 2.74585358 |
162 | regulation of meiosis I (GO:0060631) | 2.74146019 |
163 | response to X-ray (GO:0010165) | 2.74059312 |
164 | protein complex biogenesis (GO:0070271) | 2.73672200 |
165 | DNA strand renaturation (GO:0000733) | 2.73484566 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.68464079 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.17454816 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.02129744 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.67423158 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.55215937 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.39248417 |
7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.24187196 |
8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.15319009 |
9 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.13546286 |
10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.12108696 |
11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.11365228 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.00415555 |
13 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.98441949 |
14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.91766549 |
15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.87861698 |
16 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.84358105 |
17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.75655641 |
18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.73865343 |
19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.70507533 |
20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.61711818 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.60748270 |
22 | * FUS_26573619_Chip-Seq_HEK293_Human | 2.31475791 |
23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.30214050 |
24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.28505353 |
25 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.27119973 |
26 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.24550824 |
27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.24237568 |
28 | * EWS_26573619_Chip-Seq_HEK293_Human | 2.21739169 |
29 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.16644789 |
30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.13710342 |
31 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 2.11308714 |
32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.10021189 |
33 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.08419112 |
34 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03781627 |
35 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.99898486 |
36 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.99260215 |
37 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.97919601 |
38 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.97829138 |
39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.95861910 |
40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.95228320 |
41 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.92830806 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.91416950 |
43 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.90404435 |
44 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.87210930 |
45 | VDR_22108803_ChIP-Seq_LS180_Human | 1.80542792 |
46 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.77381275 |
47 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.72765953 |
48 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.72507996 |
49 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71888486 |
50 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.70404557 |
51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.66669824 |
52 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.65300490 |
53 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65209673 |
54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.64811584 |
55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.62687453 |
56 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.59789629 |
57 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.59253085 |
58 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.58085417 |
59 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.57381211 |
60 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.55615212 |
61 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.55286499 |
62 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.55263068 |
63 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.54272657 |
64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53204875 |
65 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.53161060 |
66 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.49531770 |
67 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.49038516 |
68 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.47402624 |
69 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.46162838 |
70 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43822086 |
71 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.42129937 |
72 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.40539237 |
73 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.40263746 |
74 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.39006724 |
75 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.38808798 |
76 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.38698142 |
77 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.35237155 |
78 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.32887056 |
79 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.32849555 |
80 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31891023 |
81 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29193891 |
82 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.28293868 |
83 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27760097 |
84 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25945130 |
85 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.24929049 |
86 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.23187161 |
87 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.22610283 |
88 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.19907193 |
89 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.19312703 |
90 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.17641260 |
91 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16893051 |
92 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.12575812 |
93 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.12551132 |
94 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.12068671 |
95 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.11634915 |
96 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.09879448 |
97 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08999661 |
98 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08934014 |
99 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.08345241 |
100 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.08008258 |
101 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.07470791 |
102 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06007208 |
103 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.03207618 |
104 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.02890131 |
105 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.02853995 |
106 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01813254 |
107 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.99100175 |
108 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.98528907 |
109 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.98206832 |
110 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97343001 |
111 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.97279574 |
112 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.97272891 |
113 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.95990793 |
114 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.95492047 |
115 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.93291869 |
116 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.92709649 |
117 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92612497 |
118 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92307186 |
119 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.91735604 |
120 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.91639720 |
121 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91232749 |
122 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.90647817 |
123 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.88663255 |
124 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.88494433 |
125 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.88494433 |
126 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.87855322 |
127 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87763121 |
128 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87301057 |
129 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86651673 |
130 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.86651673 |
131 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.86034399 |
132 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.85873059 |
133 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.84722404 |
134 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.84367754 |
135 | MYC_22102868_ChIP-Seq_BL_Human | 0.76468907 |
136 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.76339327 |
137 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.76061722 |
138 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.75416158 |
139 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.73436905 |
140 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.72453833 |
141 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.72271519 |
142 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.71492090 |
143 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.69444358 |
144 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.68902387 |
145 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.68592403 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.12388557 |
2 | MP0006292_abnormal_olfactory_placode | 4.36159314 |
3 | MP0010094_abnormal_chromosome_stability | 4.10824121 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.94304049 |
5 | MP0003077_abnormal_cell_cycle | 3.41173338 |
6 | MP0003111_abnormal_nucleus_morphology | 3.38002203 |
7 | MP0008058_abnormal_DNA_repair | 3.36168321 |
8 | MP0008057_abnormal_DNA_replication | 3.33085437 |
9 | MP0003123_paternal_imprinting | 3.06062171 |
10 | MP0009697_abnormal_copulation | 2.98567174 |
11 | MP0008007_abnormal_cellular_replicative | 2.87539830 |
12 | MP0002396_abnormal_hematopoietic_system | 2.26512714 |
13 | MP0008932_abnormal_embryonic_tissue | 2.23106457 |
14 | MP0009379_abnormal_foot_pigmentation | 2.22769504 |
15 | MP0001529_abnormal_vocalization | 2.13743871 |
16 | MP0004510_myositis | 2.09369798 |
17 | MP0005075_abnormal_melanosome_morpholog | 2.00235363 |
18 | MP0002102_abnormal_ear_morphology | 1.98997017 |
19 | MP0006072_abnormal_retinal_apoptosis | 1.92706081 |
20 | MP0001835_abnormal_antigen_presentation | 1.92184104 |
21 | MP0008995_early_reproductive_senescence | 1.91852970 |
22 | MP0003806_abnormal_nucleotide_metabolis | 1.88576001 |
23 | MP0003763_abnormal_thymus_physiology | 1.80659985 |
24 | MP0003718_maternal_effect | 1.79200159 |
25 | MP0003136_yellow_coat_color | 1.78880148 |
26 | MP0003890_abnormal_embryonic-extraembry | 1.74727273 |
27 | MP0008877_abnormal_DNA_methylation | 1.74124811 |
28 | MP0003786_premature_aging | 1.73161379 |
29 | MP0001730_embryonic_growth_arrest | 1.67582807 |
30 | MP0003122_maternal_imprinting | 1.66242420 |
31 | MP0000490_abnormal_crypts_of | 1.64746519 |
32 | MP0000350_abnormal_cell_proliferation | 1.60869366 |
33 | MP0003880_abnormal_central_pattern | 1.58959549 |
34 | MP0000372_irregular_coat_pigmentation | 1.56030059 |
35 | MP0003937_abnormal_limbs/digits/tail_de | 1.56024668 |
36 | MP0005174_abnormal_tail_pigmentation | 1.55034455 |
37 | MP0001293_anophthalmia | 1.52365552 |
38 | MP0003941_abnormal_skin_development | 1.46847636 |
39 | MP0004808_abnormal_hematopoietic_stem | 1.45709133 |
40 | MP0003787_abnormal_imprinting | 1.44609539 |
41 | MP0003186_abnormal_redox_activity | 1.44567515 |
42 | MP0004147_increased_porphyrin_level | 1.43202887 |
43 | MP0001984_abnormal_olfaction | 1.42551297 |
44 | MP0003656_abnormal_erythrocyte_physiolo | 1.40236896 |
45 | MP0005671_abnormal_response_to | 1.39347106 |
46 | MP0002398_abnormal_bone_marrow | 1.37493567 |
47 | MP0006054_spinal_hemorrhage | 1.37099256 |
48 | MP0002736_abnormal_nociception_after | 1.35664712 |
49 | MP0009333_abnormal_splenocyte_physiolog | 1.31883535 |
50 | MP0000313_abnormal_cell_death | 1.30843416 |
51 | MP0002132_abnormal_respiratory_system | 1.30325513 |
52 | MP0000631_abnormal_neuroendocrine_gland | 1.30280155 |
53 | MP0005253_abnormal_eye_physiology | 1.28801202 |
54 | MP0003119_abnormal_digestive_system | 1.28256365 |
55 | MP0001545_abnormal_hematopoietic_system | 1.26786632 |
56 | MP0005397_hematopoietic_system_phenotyp | 1.26786632 |
57 | MP0002019_abnormal_tumor_incidence | 1.24991596 |
58 | MP0002160_abnormal_reproductive_system | 1.24067174 |
59 | MP0002234_abnormal_pharynx_morphology | 1.23150620 |
60 | MP0002233_abnormal_nose_morphology | 1.23091341 |
61 | MP0000689_abnormal_spleen_morphology | 1.21667118 |
62 | MP0002751_abnormal_autonomic_nervous | 1.21007540 |
63 | MP0005646_abnormal_pituitary_gland | 1.20926734 |
64 | MP0010030_abnormal_orbit_morphology | 1.17701992 |
65 | MP0002722_abnormal_immune_system | 1.17008287 |
66 | MP0003121_genomic_imprinting | 1.16788243 |
67 | MP0006036_abnormal_mitochondrial_physio | 1.16422378 |
68 | MP0003195_calcinosis | 1.15635270 |
69 | MP0005551_abnormal_eye_electrophysiolog | 1.14434046 |
70 | * MP0001697_abnormal_embryo_size | 1.12806686 |
71 | MP0000703_abnormal_thymus_morphology | 1.11042344 |
72 | * MP0002210_abnormal_sex_determination | 1.10961865 |
73 | MP0000015_abnormal_ear_pigmentation | 1.10723995 |
74 | MP0001286_abnormal_eye_development | 1.10322959 |
75 | MP0004381_abnormal_hair_follicle | 1.08836591 |
76 | MP0002095_abnormal_skin_pigmentation | 1.07408181 |
77 | MP0002429_abnormal_blood_cell | 1.06547823 |
78 | MP0005367_renal/urinary_system_phenotyp | 1.06346530 |
79 | MP0000516_abnormal_urinary_system | 1.06346530 |
80 | MP0003567_abnormal_fetal_cardiomyocyte | 1.06332555 |
81 | * MP0002080_prenatal_lethality | 1.06161489 |
82 | MP0001764_abnormal_homeostasis | 1.05656255 |
83 | MP0006276_abnormal_autonomic_nervous | 1.05364239 |
84 | * MP0005389_reproductive_system_phenotype | 1.02711471 |
85 | MP0001800_abnormal_humoral_immune | 1.02542832 |
86 | MP0000647_abnormal_sebaceous_gland | 1.02297705 |
87 | MP0005380_embryogenesis_phenotype | 1.01798598 |
88 | MP0001672_abnormal_embryogenesis/_devel | 1.01798598 |
89 | MP0009785_altered_susceptibility_to | 1.01319777 |
90 | * MP0003698_abnormal_male_reproductive | 0.99100949 |
91 | MP0000716_abnormal_immune_system | 0.96821271 |
92 | MP0002090_abnormal_vision | 0.96570598 |
93 | MP0002638_abnormal_pupillary_reflex | 0.96299002 |
94 | * MP0001919_abnormal_reproductive_system | 0.95596898 |
95 | MP0000049_abnormal_middle_ear | 0.94277841 |
96 | MP0005391_vision/eye_phenotype | 0.93767053 |
97 | MP0001853_heart_inflammation | 0.93687897 |
98 | MP0002084_abnormal_developmental_patter | 0.93401688 |
99 | MP0005408_hypopigmentation | 0.92559515 |
100 | * MP0001145_abnormal_male_reproductive | 0.91091594 |
101 | MP0003315_abnormal_perineum_morphology | 0.90779388 |
102 | MP0001485_abnormal_pinna_reflex | 0.90382343 |
103 | MP0005248_abnormal_Harderian_gland | 0.90370357 |
104 | MP0000778_abnormal_nervous_system | 0.90307511 |
105 | MP0010307_abnormal_tumor_latency | 0.89064732 |
106 | MP0009703_decreased_birth_body | 0.89056307 |
107 | MP0002420_abnormal_adaptive_immunity | 0.88126484 |
108 | MP0008789_abnormal_olfactory_epithelium | 0.88120905 |
109 | MP0001819_abnormal_immune_cell | 0.87462783 |
110 | MP0002697_abnormal_eye_size | 0.85854610 |
111 | MP0002938_white_spotting | 0.84555374 |
112 | MP0005187_abnormal_penis_morphology | 0.84519485 |
113 | MP0001177_atelectasis | 0.84419793 |
114 | MP0004215_abnormal_myocardial_fiber | 0.83635536 |
115 | MP0002452_abnormal_antigen_presenting | 0.83618707 |
116 | MP0001324_abnormal_eye_pigmentation | 0.83572563 |
117 | MP0009046_muscle_twitch | 0.83269011 |
118 | MP0000858_altered_metastatic_potential | 0.83042134 |
119 | * MP0001929_abnormal_gametogenesis | 0.82389313 |
120 | MP0002111_abnormal_tail_morphology | 0.81523823 |
121 | MP0001188_hyperpigmentation | 0.80693524 |
122 | MP0000569_abnormal_digit_pigmentation | 0.79794608 |
123 | MP0003984_embryonic_growth_retardation | 0.79593213 |
124 | * MP0000653_abnormal_sex_gland | 0.79354611 |
125 | MP0002166_altered_tumor_susceptibility | 0.79285102 |
126 | MP0000427_abnormal_hair_cycle | 0.79275329 |
127 | MP0002723_abnormal_immune_serum | 0.79092710 |
128 | MP0002085_abnormal_embryonic_tissue | 0.78296098 |
129 | MP0005171_absent_coat_pigmentation | 0.77931959 |
130 | MP0002088_abnormal_embryonic_growth/wei | 0.76260054 |
131 | MP0003943_abnormal_hepatobiliary_system | 0.75888617 |
132 | MP0002086_abnormal_extraembryonic_tissu | 0.75636849 |
133 | MP0001968_abnormal_touch/_nociception | 0.75065900 |
134 | MP0003755_abnormal_palate_morphology | 0.74635522 |
135 | MP0004133_heterotaxia | 0.74534263 |
136 | MP0005084_abnormal_gallbladder_morpholo | 0.73771046 |
137 | MP0003861_abnormal_nervous_system | 0.73081092 |
138 | MP0000566_synostosis | 0.72003936 |
139 | MP0005025_abnormal_response_to | 0.69973807 |
140 | * MP0001119_abnormal_female_reproductive | 0.69243807 |
141 | MP0000678_abnormal_parathyroid_gland | 0.68807069 |
142 | MP0003724_increased_susceptibility_to | 0.67494256 |
143 | MP0002148_abnormal_hypersensitivity_rea | 0.66277706 |
144 | MP0005499_abnormal_olfactory_system | 0.65548861 |
145 | MP0005394_taste/olfaction_phenotype | 0.65548861 |
146 | MP0006035_abnormal_mitochondrial_morpho | 0.65471406 |
147 | MP0002006_tumorigenesis | 0.65064034 |
148 | MP0002405_respiratory_system_inflammati | 0.65049649 |
149 | MP0005000_abnormal_immune_tolerance | 0.64793570 |
150 | MP0002075_abnormal_coat/hair_pigmentati | 0.63218615 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.76383358 |
2 | Reticulocytopenia (HP:0001896) | 4.18577423 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 4.10310834 |
4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.05461858 |
5 | Breast hypoplasia (HP:0003187) | 3.81636188 |
6 | Degeneration of anterior horn cells (HP:0002398) | 3.61537708 |
7 | Abnormality of the anterior horn cell (HP:0006802) | 3.61537708 |
8 | Volvulus (HP:0002580) | 3.57964864 |
9 | Abnormality of the labia minora (HP:0012880) | 3.54358197 |
10 | 11 pairs of ribs (HP:0000878) | 3.36696533 |
11 | Aplastic anemia (HP:0001915) | 3.35236464 |
12 | Oral leukoplakia (HP:0002745) | 3.26964251 |
13 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.17361495 |
14 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.14936401 |
15 | Chromsome breakage (HP:0040012) | 3.11093010 |
16 | Acute encephalopathy (HP:0006846) | 3.02717736 |
17 | * Abnormality of the preputium (HP:0100587) | 3.00844796 |
18 | Microretrognathia (HP:0000308) | 2.96177207 |
19 | Abnormal lung lobation (HP:0002101) | 2.87392667 |
20 | * Meckel diverticulum (HP:0002245) | 2.84077695 |
21 | Macrocytic anemia (HP:0001972) | 2.83092760 |
22 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.81058551 |
23 | Progressive macrocephaly (HP:0004481) | 2.78687338 |
24 | * Abnormality of the ileum (HP:0001549) | 2.74200831 |
25 | Absent thumb (HP:0009777) | 2.74049172 |
26 | Type I transferrin isoform profile (HP:0003642) | 2.73760290 |
27 | * Abnormality of chromosome stability (HP:0003220) | 2.72764774 |
28 | Microvesicular hepatic steatosis (HP:0001414) | 2.70750289 |
29 | Pallor (HP:0000980) | 2.70031699 |
30 | * Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.67492206 |
31 | * Myelodysplasia (HP:0002863) | 2.63078154 |
32 | Selective tooth agenesis (HP:0001592) | 2.62977596 |
33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.61269298 |
34 | Rough bone trabeculation (HP:0100670) | 2.59181364 |
35 | * Small intestinal stenosis (HP:0012848) | 2.59021638 |
36 | * Duodenal stenosis (HP:0100867) | 2.59021638 |
37 | Intestinal atresia (HP:0011100) | 2.56675436 |
38 | Patellar aplasia (HP:0006443) | 2.50263578 |
39 | Lipid accumulation in hepatocytes (HP:0006561) | 2.48699017 |
40 | Hyperglycinemia (HP:0002154) | 2.45171892 |
41 | Colon cancer (HP:0003003) | 2.44670886 |
42 | Medulloblastoma (HP:0002885) | 2.44447117 |
43 | Agnosia (HP:0010524) | 2.43129633 |
44 | Abnormal number of incisors (HP:0011064) | 2.40228168 |
45 | Hepatocellular necrosis (HP:0001404) | 2.39498079 |
46 | Premature graying of hair (HP:0002216) | 2.39479489 |
47 | Medial flaring of the eyebrow (HP:0010747) | 2.36216986 |
48 | Supernumerary spleens (HP:0009799) | 2.34410900 |
49 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.33271608 |
50 | Hepatic necrosis (HP:0002605) | 2.33149805 |
51 | Cerebral edema (HP:0002181) | 2.32648899 |
52 | Embryonal renal neoplasm (HP:0011794) | 2.32511303 |
53 | Increased serum lactate (HP:0002151) | 2.30658038 |
54 | Mitochondrial inheritance (HP:0001427) | 2.29998655 |
55 | Oligodactyly (hands) (HP:0001180) | 2.29388528 |
56 | Hypoplasia of the pons (HP:0012110) | 2.29270936 |
57 | IgM deficiency (HP:0002850) | 2.27305467 |
58 | Cerebral hypomyelination (HP:0006808) | 2.25600988 |
59 | Cleft eyelid (HP:0000625) | 2.25148034 |
60 | Bifid tongue (HP:0010297) | 2.24678489 |
61 | Molar tooth sign on MRI (HP:0002419) | 2.22933067 |
62 | Abnormality of midbrain morphology (HP:0002418) | 2.22933067 |
63 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.21545621 |
64 | Acute necrotizing encephalopathy (HP:0006965) | 2.20913799 |
65 | * Bone marrow hypocellularity (HP:0005528) | 2.20248353 |
66 | Increased CSF lactate (HP:0002490) | 2.18733710 |
67 | Congenital primary aphakia (HP:0007707) | 2.16841546 |
68 | Gonadotropin excess (HP:0000837) | 2.14637323 |
69 | * Abnormality of the duodenum (HP:0002246) | 2.14114724 |
70 | Nephronophthisis (HP:0000090) | 2.13752531 |
71 | Pancytopenia (HP:0001876) | 2.12865937 |
72 | Horseshoe kidney (HP:0000085) | 2.11771167 |
73 | Gait imbalance (HP:0002141) | 2.10746978 |
74 | * Sloping forehead (HP:0000340) | 2.08488461 |
75 | Septo-optic dysplasia (HP:0100842) | 2.08297930 |
76 | True hermaphroditism (HP:0010459) | 2.07878274 |
77 | * Clubbing of toes (HP:0100760) | 2.05624829 |
78 | Exertional dyspnea (HP:0002875) | 2.04609545 |
79 | Abnormal biliary tract physiology (HP:0012439) | 2.03167665 |
80 | Bile duct proliferation (HP:0001408) | 2.03167665 |
81 | Ependymoma (HP:0002888) | 2.02559821 |
82 | Nephrogenic diabetes insipidus (HP:0009806) | 2.02091236 |
83 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.01422598 |
84 | Rhabdomyosarcoma (HP:0002859) | 2.01375500 |
85 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.01371311 |
86 | Carpal bone hypoplasia (HP:0001498) | 2.01303435 |
87 | Optic nerve coloboma (HP:0000588) | 2.00498193 |
88 | Abnormality of the pons (HP:0007361) | 2.00143422 |
89 | Sparse eyelashes (HP:0000653) | 1.99852824 |
90 | Genital tract atresia (HP:0001827) | 1.99049067 |
91 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.98851913 |
92 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.98851913 |
93 | Abnormal trabecular bone morphology (HP:0100671) | 1.98652723 |
94 | Abnormality of serum amino acid levels (HP:0003112) | 1.98326057 |
95 | Facial cleft (HP:0002006) | 1.97571815 |
96 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.96598309 |
97 | Cellular immunodeficiency (HP:0005374) | 1.96545330 |
98 | Lymphoma (HP:0002665) | 1.95350832 |
99 | Vaginal atresia (HP:0000148) | 1.93523651 |
100 | Methylmalonic acidemia (HP:0002912) | 1.93255509 |
101 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.93057107 |
102 | * Triphalangeal thumb (HP:0001199) | 1.92879371 |
103 | Preaxial hand polydactyly (HP:0001177) | 1.90854023 |
104 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.90693902 |
105 | Aplasia involving forearm bones (HP:0009822) | 1.89798576 |
106 | Absent forearm bone (HP:0003953) | 1.89798576 |
107 | Renal Fanconi syndrome (HP:0001994) | 1.89448660 |
108 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.87810084 |
109 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.87810084 |
110 | Glioma (HP:0009733) | 1.87152259 |
111 | Abnormality of methionine metabolism (HP:0010901) | 1.86771826 |
112 | Type 2 muscle fiber atrophy (HP:0003554) | 1.86523742 |
113 | Limb-girdle muscle atrophy (HP:0003797) | 1.86105793 |
114 | Increased hepatocellular lipid droplets (HP:0006565) | 1.85155347 |
115 | Muscle fiber atrophy (HP:0100295) | 1.84180307 |
116 | Petechiae (HP:0000967) | 1.83994486 |
117 | Abnormality of reticulocytes (HP:0004312) | 1.81317533 |
118 | Pancreatic cysts (HP:0001737) | 1.80291779 |
119 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.79599436 |
120 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.79521971 |
121 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.79521971 |
122 | Abnormal protein glycosylation (HP:0012346) | 1.79521971 |
123 | Abnormal glycosylation (HP:0012345) | 1.79521971 |
124 | Ectopic kidney (HP:0000086) | 1.79139074 |
125 | Pancreatic fibrosis (HP:0100732) | 1.78508093 |
126 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.78366364 |
127 | Gastrointestinal atresia (HP:0002589) | 1.77869968 |
128 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.77091702 |
129 | Hyperglycinuria (HP:0003108) | 1.77030721 |
130 | Missing ribs (HP:0000921) | 1.76869695 |
131 | Abnormality of glycine metabolism (HP:0010895) | 1.76564433 |
132 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.76564433 |
133 | Increased serum pyruvate (HP:0003542) | 1.75632917 |
134 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.75246155 |
135 | Absent radius (HP:0003974) | 1.74886338 |
136 | Exercise intolerance (HP:0003546) | 1.74670586 |
137 | Median cleft lip (HP:0000161) | 1.74495509 |
138 | Increased nuchal translucency (HP:0010880) | 1.73754913 |
139 | * Astigmatism (HP:0000483) | 1.72213305 |
140 | Reduced antithrombin III activity (HP:0001976) | 1.71825000 |
141 | Duplicated collecting system (HP:0000081) | 1.71092529 |
142 | Hypoplasia of the radius (HP:0002984) | 1.70524446 |
143 | Abnormality of the astrocytes (HP:0100707) | 1.70319285 |
144 | Astrocytoma (HP:0009592) | 1.70319285 |
145 | Neoplasm of the colon (HP:0100273) | 1.70208853 |
146 | Abnormal spermatogenesis (HP:0008669) | 1.69372678 |
147 | Thrombocytosis (HP:0001894) | 1.69132661 |
148 | Abnormality of the renal medulla (HP:0100957) | 1.68646983 |
149 | Asplenia (HP:0001746) | 1.68373114 |
150 | Dandy-Walker malformation (HP:0001305) | 1.68271695 |
151 | Male pseudohermaphroditism (HP:0000037) | 1.68160891 |
152 | Optic nerve hypoplasia (HP:0000609) | 1.67625481 |
153 | Sclerocornea (HP:0000647) | 1.67580834 |
154 | Lactic acidosis (HP:0003128) | 1.66709877 |
155 | Respiratory failure (HP:0002878) | 1.66692854 |
156 | Postaxial foot polydactyly (HP:0001830) | 1.65890016 |
157 | Congenital, generalized hypertrichosis (HP:0004540) | 1.65519588 |
158 | Anencephaly (HP:0002323) | 1.65309930 |
159 | Oligodactyly (HP:0012165) | 1.64674342 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STK16 | 5.18256727 |
2 | BUB1 | 4.57922582 |
3 | WEE1 | 3.58980566 |
4 | BRSK2 | 3.42199374 |
5 | EIF2AK1 | 2.96598953 |
6 | CDC7 | 2.90477435 |
7 | VRK1 | 2.63885231 |
8 | NUAK1 | 2.57585141 |
9 | WNK3 | 2.51118789 |
10 | SRPK1 | 2.42501972 |
11 | TRIM28 | 2.26884716 |
12 | ACVR1B | 2.04834975 |
13 | TLK1 | 2.04616992 |
14 | TSSK6 | 2.02594277 |
15 | BMPR1B | 2.01988409 |
16 | NME2 | 1.97129864 |
17 | VRK2 | 1.94160560 |
18 | MST4 | 1.93803702 |
19 | CDK7 | 1.93468854 |
20 | TNIK | 1.91173348 |
21 | PNCK | 1.89356790 |
22 | EIF2AK3 | 1.85585314 |
23 | PLK4 | 1.79031282 |
24 | BRSK1 | 1.70108202 |
25 | TXK | 1.69107745 |
26 | MKNK1 | 1.65082563 |
27 | PLK1 | 1.63258404 |
28 | MAP4K2 | 1.60137731 |
29 | RPS6KA4 | 1.59982094 |
30 | DYRK3 | 1.57235525 |
31 | PASK | 1.50877330 |
32 | MAP4K1 | 1.50750490 |
33 | TTK | 1.50598328 |
34 | PLK2 | 1.50219893 |
35 | CAMKK2 | 1.47227812 |
36 | ATR | 1.44931337 |
37 | FRK | 1.40996766 |
38 | CCNB1 | 1.40882249 |
39 | PLK3 | 1.38586279 |
40 | PBK | 1.37853364 |
41 | NEK2 | 1.37169795 |
42 | MKNK2 | 1.36683023 |
43 | BCR | 1.34335694 |
44 | AURKB | 1.34012330 |
45 | PIM2 | 1.31421097 |
46 | CASK | 1.31152887 |
47 | PDK2 | 1.22341917 |
48 | TESK2 | 1.16826461 |
49 | NEK1 | 1.15121036 |
50 | CSNK1G1 | 1.11058567 |
51 | ADRBK2 | 1.10957529 |
52 | MAPK13 | 1.03502296 |
53 | ZAK | 1.00180707 |
54 | BCKDK | 0.99787215 |
55 | AURKA | 0.99699101 |
56 | TAF1 | 0.98792550 |
57 | EPHA4 | 0.93811370 |
58 | STK3 | 0.90452121 |
59 | CSNK1G3 | 0.90174055 |
60 | STK4 | 0.89929007 |
61 | CHEK2 | 0.89374576 |
62 | RPS6KB2 | 0.89280861 |
63 | TGFBR1 | 0.89168070 |
64 | FLT3 | 0.88390444 |
65 | STK38L | 0.88163995 |
66 | TEC | 0.86813474 |
67 | MAP3K8 | 0.85701278 |
68 | BRAF | 0.84909922 |
69 | OXSR1 | 0.84817387 |
70 | PIM1 | 0.84666863 |
71 | CDK3 | 0.83860470 |
72 | MAP3K4 | 0.83836548 |
73 | EIF2AK2 | 0.82526078 |
74 | CSNK1G2 | 0.82179032 |
75 | CDK4 | 0.81598385 |
76 | KDR | 0.81167327 |
77 | RPS6KA5 | 0.78391933 |
78 | CSNK2A1 | 0.75300753 |
79 | BTK | 0.75160676 |
80 | CDK8 | 0.69234030 |
81 | IKBKB | 0.67925355 |
82 | CHEK1 | 0.66918013 |
83 | CSNK1A1L | 0.66679789 |
84 | NME1 | 0.66404856 |
85 | FGFR2 | 0.65606530 |
86 | INSRR | 0.64648649 |
87 | MINK1 | 0.64628187 |
88 | CSNK2A2 | 0.62187663 |
89 | DAPK1 | 0.62083875 |
90 | STK39 | 0.61814328 |
91 | FGFR1 | 0.61405946 |
92 | YES1 | 0.60924654 |
93 | NLK | 0.60106452 |
94 | CLK1 | 0.59883017 |
95 | MAP2K3 | 0.59546068 |
96 | LATS1 | 0.57990035 |
97 | ERBB4 | 0.57217094 |
98 | BRD4 | 0.56554342 |
99 | ATM | 0.55844243 |
100 | PAK4 | 0.54875025 |
101 | ERBB3 | 0.53987687 |
102 | IRAK4 | 0.53334672 |
103 | CSF1R | 0.53021421 |
104 | ZAP70 | 0.50176876 |
105 | NEK9 | 0.49864050 |
106 | PRKCG | 0.47006968 |
107 | CDK2 | 0.46618311 |
108 | ARAF | 0.46344577 |
109 | RPS6KA6 | 0.46028828 |
110 | PRKCE | 0.44707660 |
111 | CDK19 | 0.44507453 |
112 | STK10 | 0.44354807 |
113 | TAOK2 | 0.43091545 |
114 | STK24 | 0.42419053 |
115 | CSNK1E | 0.41464655 |
116 | PRKDC | 0.40953327 |
117 | MUSK | 0.40610573 |
118 | KIT | 0.40392087 |
119 | DYRK1B | 0.40276478 |
120 | CDK6 | 0.39288738 |
121 | RPS6KC1 | 0.39011188 |
122 | RPS6KL1 | 0.39011188 |
123 | PKN1 | 0.38957564 |
124 | MAP2K7 | 0.37827860 |
125 | UHMK1 | 0.37595539 |
126 | CHUK | 0.37006899 |
127 | CDK1 | 0.35527193 |
128 | IKBKE | 0.34903982 |
129 | MAP3K14 | 0.34899890 |
130 | CSNK1A1 | 0.34450394 |
131 | LYN | 0.34358085 |
132 | SYK | 0.34083796 |
133 | PINK1 | 0.32559047 |
134 | DYRK2 | 0.32321740 |
135 | MARK1 | 0.31867947 |
136 | CDK12 | 0.31709071 |
137 | MARK3 | 0.31638984 |
138 | IRAK3 | 0.31111608 |
139 | MAPKAPK5 | 0.30981961 |
140 | SIK3 | 0.30760189 |
141 | GRK1 | 0.30399978 |
142 | CDK9 | 0.30255705 |
143 | PAK1 | 0.29926436 |
144 | CSNK1D | 0.28689738 |
145 | MAP3K12 | 0.27649096 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.94601834 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.28941001 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.97410619 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.58454689 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.37976311 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 3.27451294 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.19940412 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.11895488 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.88563774 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.82680826 |
11 | RNA transport_Homo sapiens_hsa03013 | 2.69847000 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.69841459 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.45750014 |
14 | Cell cycle_Homo sapiens_hsa04110 | 2.21189259 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.19489581 |
16 | * Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.18347177 |
17 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.15425592 |
18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.13246932 |
19 | RNA degradation_Homo sapiens_hsa03018 | 2.10858039 |
20 | Protein export_Homo sapiens_hsa03060 | 1.92808993 |
21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.82235240 |
22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.71481009 |
23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.66130801 |
24 | Purine metabolism_Homo sapiens_hsa00230 | 1.60887553 |
25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.60855842 |
26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.54331944 |
27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.48428580 |
28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.45993358 |
29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.44306790 |
30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.30759649 |
31 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.30240568 |
32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29227029 |
33 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.29004853 |
34 | Parkinsons disease_Homo sapiens_hsa05012 | 1.25977464 |
35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.23063559 |
36 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.17547816 |
37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17173383 |
38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.12831994 |
39 | Huntingtons disease_Homo sapiens_hsa05016 | 1.08494658 |
40 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.06959485 |
41 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.06427786 |
42 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.04660771 |
43 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.04494757 |
44 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.02086910 |
45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.94399893 |
46 | Phototransduction_Homo sapiens_hsa04744 | 0.92090711 |
47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.89738683 |
48 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.87256288 |
49 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.77926868 |
50 | Peroxisome_Homo sapiens_hsa04146 | 0.77431836 |
51 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.75554095 |
52 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.71650979 |
53 | * Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.71214969 |
54 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.70945122 |
55 | Allograft rejection_Homo sapiens_hsa05330 | 0.69578840 |
56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.69523694 |
57 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65566683 |
58 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.63139926 |
59 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.62789411 |
60 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.62234868 |
61 | Legionellosis_Homo sapiens_hsa05134 | 0.60413840 |
62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.59700785 |
63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58921216 |
64 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.57528021 |
65 | Alzheimers disease_Homo sapiens_hsa05010 | 0.56808284 |
66 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.55974847 |
67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.55652527 |
68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.54826613 |
69 | Nicotine addiction_Homo sapiens_hsa05033 | 0.53546864 |
70 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.52967818 |
71 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.52915118 |
72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52845198 |
73 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52655705 |
74 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.52557069 |
75 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.51523258 |
76 | Measles_Homo sapiens_hsa05162 | 0.51177962 |
77 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.50573325 |
78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.49504593 |
79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49473627 |
80 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.47723553 |
81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47338726 |
82 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46496014 |
83 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.45788774 |
84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.44231497 |
85 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43396436 |
86 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.42894749 |
87 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42764944 |
88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.42738839 |
89 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.42026740 |
90 | Metabolic pathways_Homo sapiens_hsa01100 | 0.41700558 |
91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.41284922 |
92 | Asthma_Homo sapiens_hsa05310 | 0.41217270 |
93 | HTLV-I infection_Homo sapiens_hsa05166 | 0.40147920 |
94 | Sulfur relay system_Homo sapiens_hsa04122 | 0.39154186 |
95 | Thyroid cancer_Homo sapiens_hsa05216 | 0.38863686 |
96 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.37870710 |
97 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.37439471 |
98 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.36345866 |
99 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.36201264 |
100 | Alcoholism_Homo sapiens_hsa05034 | 0.36050666 |
101 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.34610025 |
102 | Viral myocarditis_Homo sapiens_hsa05416 | 0.34143038 |
103 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.33829020 |
104 | Taste transduction_Homo sapiens_hsa04742 | 0.33499251 |
105 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.32715014 |
106 | Carbon metabolism_Homo sapiens_hsa01200 | 0.32307618 |
107 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31264503 |
108 | Olfactory transduction_Homo sapiens_hsa04740 | 0.30969235 |
109 | Galactose metabolism_Homo sapiens_hsa00052 | 0.30886252 |
110 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.30028542 |
111 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29656106 |
112 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.29298571 |
113 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.28577032 |
114 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.28548922 |
115 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27833692 |
116 | Lysine degradation_Homo sapiens_hsa00310 | 0.27288558 |
117 | Shigellosis_Homo sapiens_hsa05131 | 0.25870677 |
118 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.25707433 |
119 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25356350 |
120 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.25027481 |
121 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.24985628 |
122 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.23298317 |
123 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.22738768 |
124 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.22399582 |
125 | Apoptosis_Homo sapiens_hsa04210 | 0.21243051 |
126 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.20624665 |
127 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.18601147 |
128 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.18199263 |
129 | Hepatitis B_Homo sapiens_hsa05161 | 0.18142790 |
130 | Circadian rhythm_Homo sapiens_hsa04710 | 0.17373110 |
131 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.16613828 |
132 | Influenza A_Homo sapiens_hsa05164 | 0.16573222 |
133 | Retinol metabolism_Homo sapiens_hsa00830 | 0.14188132 |
134 | Other glycan degradation_Homo sapiens_hsa00511 | 0.13002396 |
135 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.12965373 |
136 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.12405006 |
137 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.11782261 |
138 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.10770851 |
139 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.09356849 |
140 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.09001932 |
141 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.08874832 |
142 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.07655350 |
143 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.07225408 |