FAR2P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-fucose metabolic process (GO:0042354)4.43602708
2L-fucose catabolic process (GO:0042355)4.43602708
3fucose catabolic process (GO:0019317)4.43602708
4nonmotile primary cilium assembly (GO:0035058)4.15031311
5somite development (GO:0061053)4.06288381
6indolalkylamine metabolic process (GO:0006586)3.87424686
7detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.56811511
8indole-containing compound catabolic process (GO:0042436)3.47747263
9indolalkylamine catabolic process (GO:0046218)3.47747263
10tryptophan catabolic process (GO:0006569)3.47747263
11reflex (GO:0060004)3.47402547
12behavioral response to nicotine (GO:0035095)3.43678333
13neural tube formation (GO:0001841)3.34765863
14adaptation of signaling pathway (GO:0023058)3.33403727
15cellular ketone body metabolic process (GO:0046950)3.30161571
16artery development (GO:0060840)3.25502668
17response to pheromone (GO:0019236)3.24853473
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.22398644
19kynurenine metabolic process (GO:0070189)3.22349665
20epithelial cilium movement (GO:0003351)3.13603937
21photoreceptor cell maintenance (GO:0045494)3.12866325
22nephron epithelium morphogenesis (GO:0072088)3.12210838
23nephron tubule morphogenesis (GO:0072078)3.12210838
24cilium or flagellum-dependent cell motility (GO:0001539)3.05985758
25tryptophan metabolic process (GO:0006568)2.99550401
26negative regulation of sodium ion transport (GO:0010766)2.98676026
27spinal cord motor neuron differentiation (GO:0021522)2.97694742
28regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.95373019
29righting reflex (GO:0060013)2.93011952
30ketone body metabolic process (GO:1902224)2.90886542
31monoubiquitinated protein deubiquitination (GO:0035520)2.88075595
32negative regulation of systemic arterial blood pressure (GO:0003085)2.87675311
33regulation of translation, ncRNA-mediated (GO:0045974)2.86332420
34negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.86332420
35negative regulation of translation, ncRNA-mediated (GO:0040033)2.86332420
36regulation of non-canonical Wnt signaling pathway (GO:2000050)2.85899919
37detection of light stimulus involved in visual perception (GO:0050908)2.84811689
38detection of light stimulus involved in sensory perception (GO:0050962)2.84811689
39limb bud formation (GO:0060174)2.84170240
40indole-containing compound metabolic process (GO:0042430)2.83230352
41kidney morphogenesis (GO:0060993)2.82908801
42cellular response to sterol (GO:0036315)2.78599888
43cilium movement (GO:0003341)2.78264448
44synapsis (GO:0007129)2.76460593
45cilium organization (GO:0044782)2.75394343
46G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.75023026
47hindbrain development (GO:0030902)2.72784850
48cilium morphogenesis (GO:0060271)2.71664406
49positive regulation of oligodendrocyte differentiation (GO:0048714)2.70153770
50retinal ganglion cell axon guidance (GO:0031290)2.70048148
51piRNA metabolic process (GO:0034587)2.69392333
52thalamus development (GO:0021794)2.69068507
53serotonin metabolic process (GO:0042428)2.65508882
54cilium assembly (GO:0042384)2.64989650
55DNA methylation involved in gamete generation (GO:0043046)2.61951512
56peptidyl-histidine modification (GO:0018202)2.60654796
57protein polyglutamylation (GO:0018095)2.60598795
58retina homeostasis (GO:0001895)2.60594755
59retinal metabolic process (GO:0042574)2.60272980
60regulation of gene silencing by RNA (GO:0060966)2.60172796
61regulation of posttranscriptional gene silencing (GO:0060147)2.60172796
62regulation of gene silencing by miRNA (GO:0060964)2.60172796
63positive regulation of glycolytic process (GO:0045821)2.57813704
64signal peptide processing (GO:0006465)2.57745096
65centriole replication (GO:0007099)2.55915320
66fucosylation (GO:0036065)2.55780122
67regulation of hippo signaling (GO:0035330)2.55053541
68prostate gland growth (GO:0060736)2.54605022
69short-term memory (GO:0007614)2.53464341
70mannosylation (GO:0097502)2.53324272
71biotin metabolic process (GO:0006768)2.52492844
72regulation of cilium movement (GO:0003352)2.50935489
73detection of temperature stimulus (GO:0016048)2.50650825
74primary amino compound metabolic process (GO:1901160)2.48992632
75regulation of mesoderm development (GO:2000380)2.48285611
76intraciliary transport (GO:0042073)2.47913035
77replication fork processing (GO:0031297)2.46836726
78amine catabolic process (GO:0009310)2.46752793
79cellular biogenic amine catabolic process (GO:0042402)2.46752793
80embryonic pattern specification (GO:0009880)2.45957186
81aromatic amino acid family catabolic process (GO:0009074)2.44825957
82behavioral response to ethanol (GO:0048149)2.44345121
83smoothened signaling pathway (GO:0007224)2.42957890
84pyrimidine nucleobase catabolic process (GO:0006208)2.41716847
85renal tubule morphogenesis (GO:0061333)2.40793668
86benzene-containing compound metabolic process (GO:0042537)2.40443812
87male meiosis (GO:0007140)2.39733117
88regulation of glucokinase activity (GO:0033131)2.39722435
89regulation of hexokinase activity (GO:1903299)2.39722435
90reciprocal meiotic recombination (GO:0007131)2.39712064
91reciprocal DNA recombination (GO:0035825)2.39712064
92dorsal/ventral neural tube patterning (GO:0021904)2.39032734
93transmission of nerve impulse (GO:0019226)2.36028616
94pancreas development (GO:0031016)2.34851775
95photoreceptor cell development (GO:0042461)2.34591361
96protein prenylation (GO:0018342)2.34142878
97prenylation (GO:0097354)2.34142878
98lung lobe morphogenesis (GO:0060463)2.33193882
99negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.31079921
100negative regulation of transcription regulatory region DNA binding (GO:2000678)2.30504848

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.64140326
2ZNF274_21170338_ChIP-Seq_K562_Hela3.45463499
3VDR_22108803_ChIP-Seq_LS180_Human3.13363709
4GBX2_23144817_ChIP-Seq_PC3_Human3.00603121
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.75293599
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.60717753
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.42208176
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.34809547
9IGF1R_20145208_ChIP-Seq_DFB_Human2.30671283
10EWS_26573619_Chip-Seq_HEK293_Human2.29879924
11PIAS1_25552417_ChIP-Seq_VCAP_Human2.29565753
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.22896856
13TAF15_26573619_Chip-Seq_HEK293_Human2.21128921
14CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.20442287
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.19677887
16FUS_26573619_Chip-Seq_HEK293_Human2.19499929
17P300_19829295_ChIP-Seq_ESCs_Human2.15705535
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.08698285
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.03360826
20ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.02865403
21RBPJ_22232070_ChIP-Seq_NCS_Mouse2.02499691
22BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.96136946
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.88379648
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.87643939
25ER_23166858_ChIP-Seq_MCF-7_Human1.86073613
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83342418
27AR_21572438_ChIP-Seq_LNCaP_Human1.80681882
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76126580
29PCGF2_27294783_Chip-Seq_NPCs_Mouse1.67875861
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67384697
31STAT3_23295773_ChIP-Seq_U87_Human1.67149308
32MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.66319708
33SMAD4_21799915_ChIP-Seq_A2780_Human1.65063234
34SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.62901025
35BCAT_22108803_ChIP-Seq_LS180_Human1.59702913
36TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58829078
37POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.58829078
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56147188
39TCF4_23295773_ChIP-Seq_U87_Human1.53704260
40AR_25329375_ChIP-Seq_VCAP_Human1.53085382
41SMAD3_21741376_ChIP-Seq_EPCs_Human1.52421593
42MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51999989
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.50847130
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.50380963
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.47232112
46SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47022906
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.47017052
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.45300947
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44590570
50RNF2_27304074_Chip-Seq_NSC_Mouse1.42603126
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.41658719
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40602591
53CBP_20019798_ChIP-Seq_JUKART_Human1.40602591
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39437113
55RUNX2_22187159_ChIP-Seq_PCA_Human1.35717024
56TCF4_22108803_ChIP-Seq_LS180_Human1.32263427
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30425158
58NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.29374118
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.27365841
60SOX2_19829295_ChIP-Seq_ESCs_Human1.26532055
61NANOG_19829295_ChIP-Seq_ESCs_Human1.26532055
62TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24041693
63EZH2_27294783_Chip-Seq_NPCs_Mouse1.23211767
64TP53_22573176_ChIP-Seq_HFKS_Human1.22449261
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.20880170
66KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19731502
67FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19307924
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18555119
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17901749
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.17390076
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.14779733
72TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.12389046
73PRDM14_20953172_ChIP-Seq_ESCs_Human1.10730611
74EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09183830
75SOX2_21211035_ChIP-Seq_LN229_Gbm1.08210808
76IRF1_19129219_ChIP-ChIP_H3396_Human1.08172333
77CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06823535
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05625389
79TP63_19390658_ChIP-ChIP_HaCaT_Human1.05617114
80CDX2_22108803_ChIP-Seq_LS180_Human1.03972773
81CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03529017
82P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03013990
83RXR_22108803_ChIP-Seq_LS180_Human1.02995440
84MYC_18940864_ChIP-ChIP_HL60_Human1.02785114
85FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02140364
86FOXA1_25329375_ChIP-Seq_VCAP_Human1.02140364
87FOXA1_21572438_ChIP-Seq_LNCaP_Human1.00898851
88AHR_22903824_ChIP-Seq_MCF-7_Human1.00834759
89E2F1_18555785_Chip-Seq_ESCs_Mouse1.00110768
90P53_22387025_ChIP-Seq_ESCs_Mouse0.99988227
91AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.99691617
92REST_21632747_ChIP-Seq_MESCs_Mouse0.99478586
93AR_20517297_ChIP-Seq_VCAP_Human0.98005196
94CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.96459923
95GABP_17652178_ChIP-ChIP_JURKAT_Human0.96309468
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95884557
97STAT3_18555785_Chip-Seq_ESCs_Mouse0.95582190
98CRX_20693478_ChIP-Seq_RETINA_Mouse0.95555534
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.94996891
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94757173

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002736_abnormal_nociception_after2.90742095
2MP0002234_abnormal_pharynx_morphology2.78311391
3MP0000569_abnormal_digit_pigmentation2.69432164
4MP0003195_calcinosis2.53396887
5MP0003011_delayed_dark_adaptation2.46288384
6MP0001968_abnormal_touch/_nociception2.38213159
7MP0002102_abnormal_ear_morphology2.37199798
8MP0004043_abnormal_pH_regulation2.24640701
9MP0005551_abnormal_eye_electrophysiolog2.24365610
10MP0002938_white_spotting2.08583373
11MP0003136_yellow_coat_color2.08252588
12MP0008877_abnormal_DNA_methylation2.08166755
13MP0002735_abnormal_chemical_nociception2.01229642
14MP0006292_abnormal_olfactory_placode1.91320369
15MP0003890_abnormal_embryonic-extraembry1.85185613
16MP0006072_abnormal_retinal_apoptosis1.79036983
17MP0005253_abnormal_eye_physiology1.74789902
18MP0001293_anophthalmia1.68134479
19MP0003122_maternal_imprinting1.66032480
20MP0005167_abnormal_blood-brain_barrier1.55343290
21MP0003283_abnormal_digestive_organ1.55281547
22MP0005646_abnormal_pituitary_gland1.54876600
23MP0008995_early_reproductive_senescence1.53408967
24MP0010030_abnormal_orbit_morphology1.51582981
25MP0000631_abnormal_neuroendocrine_gland1.50854952
26MP0009046_muscle_twitch1.50220981
27MP0000372_irregular_coat_pigmentation1.45218711
28MP0002090_abnormal_vision1.42863534
29MP0003937_abnormal_limbs/digits/tail_de1.42188836
30MP0001501_abnormal_sleep_pattern1.40962366
31MP0008057_abnormal_DNA_replication1.40216988
32MP0001485_abnormal_pinna_reflex1.38148074
33MP0006276_abnormal_autonomic_nervous1.37277598
34MP0000383_abnormal_hair_follicle1.33767691
35MP0003938_abnormal_ear_development1.33284436
36MP0002233_abnormal_nose_morphology1.30537066
37MP0004142_abnormal_muscle_tone1.27957614
38MP0000778_abnormal_nervous_system1.22323303
39MP0001984_abnormal_olfaction1.20257524
40MP0004742_abnormal_vestibular_system1.20120322
41MP0005085_abnormal_gallbladder_physiolo1.20012390
42MP0003119_abnormal_digestive_system1.19613678
43MP0000566_synostosis1.19327082
44MP0002733_abnormal_thermal_nociception1.17651911
45MP0002557_abnormal_social/conspecific_i1.16295676
46MP0001486_abnormal_startle_reflex1.15523625
47MP0003698_abnormal_male_reproductive1.11762707
48MP0005377_hearing/vestibular/ear_phenot1.10929760
49MP0003878_abnormal_ear_physiology1.10929760
50MP0005391_vision/eye_phenotype1.10751390
51MP0008789_abnormal_olfactory_epithelium1.08946728
52MP0002638_abnormal_pupillary_reflex1.06868408
53MP0008872_abnormal_physiological_respon1.06839470
54MP0003880_abnormal_central_pattern1.06301099
55MP0002751_abnormal_autonomic_nervous1.06145992
56MP0003718_maternal_effect1.06093070
57MP0002210_abnormal_sex_determination1.05492769
58MP0001970_abnormal_pain_threshold1.05199942
59MP0009745_abnormal_behavioral_response1.05105232
60MP0005408_hypopigmentation1.04460232
61MP0002160_abnormal_reproductive_system1.04107298
62MP0001286_abnormal_eye_development1.02841165
63MP0003121_genomic_imprinting1.02517567
64MP0002184_abnormal_innervation1.01966553
65MP0002272_abnormal_nervous_system1.01669298
66MP0005195_abnormal_posterior_eye1.01354841
67MP0001929_abnormal_gametogenesis1.01111742
68MP0000026_abnormal_inner_ear1.00640984
69MP0005645_abnormal_hypothalamus_physiol0.99025571
70MP0005174_abnormal_tail_pigmentation0.98675172
71MP0000427_abnormal_hair_cycle0.98674187
72MP0002752_abnormal_somatic_nervous0.97916076
73MP0002572_abnormal_emotion/affect_behav0.97467858
74MP0002067_abnormal_sensory_capabilities0.96576979
75MP0000049_abnormal_middle_ear0.95752193
76MP0003755_abnormal_palate_morphology0.94779098
77MP0004133_heterotaxia0.93390654
78MP0001324_abnormal_eye_pigmentation0.93246565
79MP0005386_behavior/neurological_phenoty0.92517524
80MP0004924_abnormal_behavior0.92517524
81MP0000955_abnormal_spinal_cord0.92076438
82MP0001529_abnormal_vocalization0.91699874
83MP0001986_abnormal_taste_sensitivity0.89894714
84MP0000613_abnormal_salivary_gland0.89853083
85MP0000653_abnormal_sex_gland0.89644528
86MP0001145_abnormal_male_reproductive0.88377014
87MP0005187_abnormal_penis_morphology0.88194011
88MP0003942_abnormal_urinary_system0.87127624
89MP0002734_abnormal_mechanical_nocicepti0.86234243
90MP0002653_abnormal_ependyma_morphology0.84885142
91MP0002837_dystrophic_cardiac_calcinosis0.84823811
92MP0002876_abnormal_thyroid_physiology0.83768765
93MP0003646_muscle_fatigue0.83555690
94MP0002282_abnormal_trachea_morphology0.82711023
95MP0002822_catalepsy0.82153714
96MP0008058_abnormal_DNA_repair0.81711625
97MP0002928_abnormal_bile_duct0.81458227
98MP0005410_abnormal_fertilization0.80599436
99MP0004145_abnormal_muscle_electrophysio0.78411549
100MP0003787_abnormal_imprinting0.78336800

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.29684762
2Pancreatic fibrosis (HP:0100732)4.10111264
3Molar tooth sign on MRI (HP:0002419)3.77033703
4Abnormality of midbrain morphology (HP:0002418)3.77033703
5True hermaphroditism (HP:0010459)3.70910712
6Nephronophthisis (HP:0000090)3.51011035
7Hyperventilation (HP:0002883)3.29615182
8Abnormality of the renal cortex (HP:0011035)3.22194892
9Abnormality of the renal medulla (HP:0100957)3.19555550
10Medial flaring of the eyebrow (HP:0010747)3.09084449
11Cystic liver disease (HP:0006706)3.04232586
12Tubular atrophy (HP:0000092)2.89741453
13Type II lissencephaly (HP:0007260)2.85112229
14Cerebellar dysplasia (HP:0007033)2.73136270
15Hypothermia (HP:0002045)2.71538243
16Bilateral microphthalmos (HP:0007633)2.68541400
17Congenital stationary night blindness (HP:0007642)2.65590944
18Gait imbalance (HP:0002141)2.56855979
19Congenital primary aphakia (HP:0007707)2.54949671
20Chronic hepatic failure (HP:0100626)2.53168126
21Attenuation of retinal blood vessels (HP:0007843)2.53022245
22Hyperglycinuria (HP:0003108)2.48648001
23Sclerocornea (HP:0000647)2.48355699
24Genetic anticipation (HP:0003743)2.45759763
25Hyperglycinemia (HP:0002154)2.44401840
26Genital tract atresia (HP:0001827)2.40082179
27Anencephaly (HP:0002323)2.36615825
28Vaginal atresia (HP:0000148)2.35405367
29Aplasia/Hypoplasia of the tibia (HP:0005772)2.34679680
30Nephrogenic diabetes insipidus (HP:0009806)2.32721580
31Aplasia/Hypoplasia of the tongue (HP:0010295)2.31216913
32Intestinal atresia (HP:0011100)2.29663623
33Decreased circulating renin level (HP:0003351)2.28702421
34Progressive cerebellar ataxia (HP:0002073)2.26093373
35Lissencephaly (HP:0001339)2.24343242
36Abnormal drinking behavior (HP:0030082)2.23191780
37Polydipsia (HP:0001959)2.23191780
38Anophthalmia (HP:0000528)2.23099768
39Gaze-evoked nystagmus (HP:0000640)2.21826029
40Renal cortical cysts (HP:0000803)2.19620729
41Midline defect of the nose (HP:0004122)2.16476714
42Preaxial foot polydactyly (HP:0001841)2.15171062
43Poor coordination (HP:0002370)2.14118574
44Postaxial foot polydactyly (HP:0001830)2.14106568
45Small hand (HP:0200055)2.13129821
46Colon cancer (HP:0003003)2.11741379
47Congenital hepatic fibrosis (HP:0002612)2.09282561
48Large for gestational age (HP:0001520)2.08520389
49Male pseudohermaphroditism (HP:0000037)2.03930901
50Broad-based gait (HP:0002136)2.03751332
51Bifid tongue (HP:0010297)2.03745435
52Bile duct proliferation (HP:0001408)2.02733001
53Abnormal biliary tract physiology (HP:0012439)2.02733001
54Abnormality of the labia minora (HP:0012880)2.02028522
55Hypoplasia of the pons (HP:0012110)2.01027851
56Congenital, generalized hypertrichosis (HP:0004540)1.99497202
57Preaxial hand polydactyly (HP:0001177)1.98819944
58Postaxial hand polydactyly (HP:0001162)1.96411228
59Tented upper lip vermilion (HP:0010804)1.96409135
60Optic nerve hypoplasia (HP:0000609)1.95975913
61Abolished electroretinogram (ERG) (HP:0000550)1.95238058
62Abnormality of serine family amino acid metabolism (HP:0010894)1.95074506
63Abnormality of glycine metabolism (HP:0010895)1.95074506
64Tubulointerstitial abnormality (HP:0001969)1.92061633
65Tubulointerstitial nephritis (HP:0001970)1.91959737
66Furrowed tongue (HP:0000221)1.89913164
67Hypoplastic labia majora (HP:0000059)1.87655165
68Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.86214479
69Protruding tongue (HP:0010808)1.85643767
70Abnormality of the pons (HP:0007361)1.83775833
71Febrile seizures (HP:0002373)1.83773906
72Exotropia (HP:0000577)1.80459366
73Pendular nystagmus (HP:0012043)1.79732122
74Bony spicule pigmentary retinopathy (HP:0007737)1.79322781
75Proximal tubulopathy (HP:0000114)1.77536081
76Absent speech (HP:0001344)1.77443324
77Fair hair (HP:0002286)1.76031169
78Dynein arm defect of respiratory motile cilia (HP:0012255)1.75630093
79Absent/shortened dynein arms (HP:0200106)1.75630093
80Hypoplastic ischia (HP:0003175)1.72083106
81Abnormality of the labia majora (HP:0012881)1.70990914
82Abnormal rod and cone electroretinograms (HP:0008323)1.70987499
83Polyuria (HP:0000103)1.70565197
84Enlarged kidneys (HP:0000105)1.69738610
85Type I transferrin isoform profile (HP:0003642)1.67231706
86Abnormal ciliary motility (HP:0012262)1.66466829
87Highly arched eyebrow (HP:0002553)1.66311796
88Tachypnea (HP:0002789)1.65101611
89Dandy-Walker malformation (HP:0001305)1.63715025
90Hypoplasia of the ulna (HP:0003022)1.63531434
91Multicystic kidney dysplasia (HP:0000003)1.63438365
92Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.63176663
93Aplasia/Hypoplasia of the uvula (HP:0010293)1.63007716
94Tubulointerstitial fibrosis (HP:0005576)1.62477137
95Prominent nasal bridge (HP:0000426)1.60454690
96Anal stenosis (HP:0002025)1.60270047
97Amelogenesis imperfecta (HP:0000705)1.60148504
98Volvulus (HP:0002580)1.59277068
99Abnormality of the vitreous humor (HP:0004327)1.57862621
100Absent eyebrow (HP:0002223)1.57481254

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.55583817
2AKT33.81799122
3MAP4K22.86839896
4CASK2.86789999
5WNK42.58052811
6WNK32.54312726
7BMPR1B2.24356098
8ACVR1B2.15922646
9TRIM282.12537436
10PNCK1.98744222
11STK391.86996641
12NUAK11.80541386
13STK38L1.79874059
14ADRBK21.79492371
15PINK11.72386779
16TAOK31.71869927
17MKNK21.67216400
18LATS11.66644097
19GRK11.60916493
20NTRK31.57614426
21BRSK21.56682233
22MARK11.56326733
23INSRR1.51281174
24MAP3K41.47132561
25ZAK1.43771074
26TAF11.42934468
27MAPK131.30559618
28BCR1.29631257
29SGK21.27424410
30STK31.21801755
31EPHA41.15551014
32NME11.14715713
33MKNK11.14328114
34CAMK1G1.13747332
35EPHB21.10978011
36WEE11.07655136
37OXSR11.06530228
38PAK31.06305503
39PLK41.02864153
40DAPK21.00760529
41FGFR20.98414837
42TGFBR10.95958068
43PRKCG0.90382320
44BRD40.86309921
45TNIK0.83730863
46CAMK1D0.81635317
47SGK4940.80055419
48SGK2230.80055419
49PRKCE0.79949971
50PTK2B0.74446702
51TLK10.72103053
52STK160.68186856
53ERBB20.68135643
54PIK3CG0.65549149
55ADRBK10.64546577
56EIF2AK30.64388918
57OBSCN0.62283691
58TNK20.61480335
59PASK0.60711224
60VRK10.60598851
61PIK3CA0.59690367
62CSNK1A1L0.58042985
63CSNK1G10.56787983
64PRKAA10.56582377
65NEK20.55945544
66ERBB30.55580666
67FGFR10.53415102
68DYRK20.52800581
69CDK30.52512228
70EIF2AK20.51880020
71PRKAA20.51425407
72PLK30.49222478
73CAMK10.48804338
74MAPKAPK30.47601346
75ATM0.47253650
76NTRK20.46974849
77CSNK1E0.46188493
78CDC70.45597332
79CSNK1A10.45553915
80DYRK30.45003657
81PRKACA0.44881573
82STK110.44857190
83WNK10.44254109
84BRSK10.43251417
85PLK20.42848565
86KSR10.42812446
87EIF2AK10.42641629
88STK380.42299302
89CSNK1G20.41644273
90MAP3K70.40116261
91CAMK2A0.39704823
92CHEK20.39691006
93CSNK1D0.39581919
94SGK30.39545811
95PRKACB0.38285929
96ATR0.36808394
97MAPKAPK50.32960818
98FER0.32335594
99SGK10.31835624
100FLT30.31791491

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.79270339
2Butanoate metabolism_Homo sapiens_hsa006502.74449437
3Phototransduction_Homo sapiens_hsa047442.38871812
4Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.31681634
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.22798113
6One carbon pool by folate_Homo sapiens_hsa006702.16427214
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.11906019
8Tryptophan metabolism_Homo sapiens_hsa003802.04836656
9Nicotine addiction_Homo sapiens_hsa050332.03537298
10ABC transporters_Homo sapiens_hsa020101.99912100
11Nitrogen metabolism_Homo sapiens_hsa009101.96925156
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.89973958
13Linoleic acid metabolism_Homo sapiens_hsa005911.88746854
14Homologous recombination_Homo sapiens_hsa034401.86950481
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.81362350
16Basal transcription factors_Homo sapiens_hsa030221.76721444
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.76342197
18Propanoate metabolism_Homo sapiens_hsa006401.73266227
19Taste transduction_Homo sapiens_hsa047421.69438411
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.67602650
21Protein export_Homo sapiens_hsa030601.65381180
22Selenocompound metabolism_Homo sapiens_hsa004501.65161788
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.54265736
24Oxidative phosphorylation_Homo sapiens_hsa001901.53023621
25Olfactory transduction_Homo sapiens_hsa047401.50143945
26Primary bile acid biosynthesis_Homo sapiens_hsa001201.49746802
27beta-Alanine metabolism_Homo sapiens_hsa004101.45038553
28Histidine metabolism_Homo sapiens_hsa003401.43270263
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36201772
30Ether lipid metabolism_Homo sapiens_hsa005651.36055632
31Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.32259289
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29798592
33Retinol metabolism_Homo sapiens_hsa008301.21830255
34Steroid hormone biosynthesis_Homo sapiens_hsa001401.21374597
35Fanconi anemia pathway_Homo sapiens_hsa034601.20141378
36Chemical carcinogenesis_Homo sapiens_hsa052041.17370153
37Vitamin digestion and absorption_Homo sapiens_hsa049771.16512414
38Morphine addiction_Homo sapiens_hsa050321.12365704
39Serotonergic synapse_Homo sapiens_hsa047261.08928088
40Huntingtons disease_Homo sapiens_hsa050161.08643650
41Hedgehog signaling pathway_Homo sapiens_hsa043401.07710202
42Ribosome_Homo sapiens_hsa030101.06405509
43Parkinsons disease_Homo sapiens_hsa050121.05184949
44Basal cell carcinoma_Homo sapiens_hsa052171.04082774
45Glutamatergic synapse_Homo sapiens_hsa047241.03180658
46RNA polymerase_Homo sapiens_hsa030200.98145659
47RNA degradation_Homo sapiens_hsa030180.97904564
48Circadian entrainment_Homo sapiens_hsa047130.97900405
49GABAergic synapse_Homo sapiens_hsa047270.97501945
50Caffeine metabolism_Homo sapiens_hsa002320.97387903
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97307570
52Non-homologous end-joining_Homo sapiens_hsa034500.92902060
53Peroxisome_Homo sapiens_hsa041460.91969057
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.91053661
55Insulin secretion_Homo sapiens_hsa049110.89705781
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89369591
57Lysine degradation_Homo sapiens_hsa003100.88928168
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.88736486
59Mineral absorption_Homo sapiens_hsa049780.87618020
60Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.85509777
61Circadian rhythm_Homo sapiens_hsa047100.85022693
62Fat digestion and absorption_Homo sapiens_hsa049750.83021879
63Steroid biosynthesis_Homo sapiens_hsa001000.81903550
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75172008
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.74108044
66Fatty acid metabolism_Homo sapiens_hsa012120.74073291
67Glycerolipid metabolism_Homo sapiens_hsa005610.72861605
68Ovarian steroidogenesis_Homo sapiens_hsa049130.72301110
69Cardiac muscle contraction_Homo sapiens_hsa042600.71917370
70Sulfur relay system_Homo sapiens_hsa041220.71916696
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.70829982
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68726022
73Fatty acid biosynthesis_Homo sapiens_hsa000610.68512499
74TGF-beta signaling pathway_Homo sapiens_hsa043500.67480001
75Alzheimers disease_Homo sapiens_hsa050100.67115380
76Bile secretion_Homo sapiens_hsa049760.66238747
77Fatty acid degradation_Homo sapiens_hsa000710.64978046
78Metabolic pathways_Homo sapiens_hsa011000.63369123
79Purine metabolism_Homo sapiens_hsa002300.62641698
80Dopaminergic synapse_Homo sapiens_hsa047280.59872964
81Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.59050849
82Cocaine addiction_Homo sapiens_hsa050300.58196538
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57650765
84Arginine and proline metabolism_Homo sapiens_hsa003300.56622796
85Calcium signaling pathway_Homo sapiens_hsa040200.55952819
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53441338
87RNA transport_Homo sapiens_hsa030130.51513731
88Regulation of autophagy_Homo sapiens_hsa041400.51289733
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.50620708
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.49294629
91Salivary secretion_Homo sapiens_hsa049700.48816253
92Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48414772
93Hippo signaling pathway_Homo sapiens_hsa043900.47987140
94Arachidonic acid metabolism_Homo sapiens_hsa005900.42678808
95Amphetamine addiction_Homo sapiens_hsa050310.41528247
96cAMP signaling pathway_Homo sapiens_hsa040240.41420443
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41115227
98Tyrosine metabolism_Homo sapiens_hsa003500.38992755
99Nucleotide excision repair_Homo sapiens_hsa034200.38306596
100Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38014190

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